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Reuse and recycling of non-hazardous construction and demolition waste and industrial byproducts in the construction industry is vital to promote environmentally sound waste management. In particular, the effective utilization of sludge and waste clay bricks is greatly required in developing countries. This paper studied compaction characteristics and the California bearing ratio (CBR) of water treatment sludge (WTS) blended with clay brick aggregates for the road subgrade application. Raw and waste clay bricks from Vietnam were used for preparing clay brick (CB) and recycled clay brick (RCB) aggregates of three different particle sizes, Coarse 10- 30 mm, Graded 2-30 mm, and Fine 2-10 mm. In addition, fine residues of clay bricks with a size of < 2 mm were tested. WTS sieved under 2.0 mm blended with CB/RCB aggregates with different mixing proportions (f) were used for compaction and CBR tests in the laboratory. Results showed that the measured maximum dry densities (MDD) were dependent solely on mixing proportion f and increased linearly with f irrespective of blended fractions of CB/RCB aggregates. Unlike MDD, the measured CBR was dependent on both f and blended fractions. Especially, the WTS blended with coarse and graded fractions with a range of 60 ≤ f ≤ 80% showed a significant improvement in CBR (>100%). Due to its limited particle breakage and high CBR, the WTS blended with graded CB/RCB aggregates was preferable for the road subgrade application. [ABSTRACT FROM AUTHOR]