1. Diagnostics in Ebola Virus Disease in Resource-Rich and Resource-Limited Settings.
- Author
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Shorten, Robert J, Brown, Colin S, Jacobs, Michael, Rattenbury, Simon, Simpson, Andrew J., and Mepham, Stephen
- Subjects
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EBOLA virus disease , *EBOLA virus disease prevention , *PANDEMICS , *DISEASE progression , *PUBLIC health , *DIAGNOSIS - Abstract
The Ebola virus disease (EVD) outbreak in West Africa was unprecedented in scale and location. Limited access to both diagnostic and supportive pathology assays in both resource-rich and resource-limited settings had a detrimental effect on the identification and isolation of cases as well as individual patient management. Limited access to such assays in resource-rich settings resulted in delays in differentiating EVD from other illnesses in returning travellers, in turn utilising valuable resources until a diagnosis could be made. This had a much greater impact in West Africa, where it contributed to the initial failure to contain the outbreak. This review explores diagnostic assays of use in EVD in both resource-rich and resource-limited settings, including their respective limitations, and some novel assays and approaches that may be of use in future outbreaks. [ABSTRACT FROM AUTHOR]
- Published
- 2016
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