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Abstract: Previous studies have shown that it is very difficult to distinguish human-induced changes from those caused by natural forcing. In this paper we try to quantify the influence of land use and water management on flows of the Upper Narew River in north-east Poland. Apart from climatic and land use changes, the Upper Narew catchment was changed by the construction of a storage reservoir at Siemianówka, near Bondary, on the upstream reach of the river. We apply four different approaches to analysing the changes in flow regime and catchment response for the periods before and after reservoir construction. First we estimate the cumulative distribution functions for low and high flow events. The second approach is a time series analysis of flow variation over the whole length of available data and the derivation of cumulative distribution functions for the flows and 0.25–0.75 quantiles followed by a statistical analysis of the number of events below and above the thresholds and their duration. The third approach consists of the application of the Wittenberg baseflow separation method and tests for changes in baseflow indices. In the fourth approach an analysis of changes in flow regime is performed by studying the changes in transfer function-based flow model parameters. Long-term changes in land use are assessed using previous studies of the catchment and the analysis of Corine land cover data and government yearbooks. The results show that different methods explain different aspects of changes in the catchment and flow regime due to climatic changes and changes in land use and water management practices. The analysis of cumulative distribution functions gave evidence of the influence of Siemianówka reservoir on low flows which was also confirmed by the low flow analysis using the Wittenberg approach. The STF analysis of flows indicates the existence of changes in flow regime that can be attributed to the roughness changes in the channel. [Copyright &y& Elsevier]