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A recent study conducted at Wuhan University in China has developed a new method for detecting cancer biomarkers. The researchers constructed a DNA walker nanomachine aptasensor using gold nanoparticles, which allows for the simultaneous detection of dual cancer biomarkers. The aptasensor was successful in detecting carcinoembryonic antigen (CEA) and mucin-1 (MUC-1) in a specific range, and has the potential for early disease diagnosis. This research was supported by the National Natural Science Foundation of China (NSFC) and has been peer-reviewed. [Extracted from the article]

A report from Huazhong Agricultural University in Wuhan, China discusses the synthesis of gold nanoparticles (AuNPs) capped with a macrocyclic compound called b-cyclodextrin (b-CD) and their potential application in colorimetric assays for ascorbic acid and Salmonella. The researchers found that the b-CD@AuNPs exhibited peroxidase-like activities and could be used as catalysts for color changes in the presence of specific substrates. They developed a colorimetric assay for ascorbic acid with a low limit of detection and a one-step assay for Salmonella with high sensitivity and specificity. The study suggests that b-CD@AuNPs could be used as a sensing platform in the food industry. [Extracted from the article]

Researchers from Wuhan University in China have developed a new method for enhanced cancer photothermal therapy using gold nanoparticles. The researchers utilized a bioorthogonal "click and release" reaction to trigger the aggregation of gold nanoparticles, which were combined with a released chemotherapeutic drug. The resulting nanoaggregates exhibited highly photothermal activity and were able to sensitize cancer cells to photothermal therapy. This research has the potential to improve the therapeutic outcome of cancer treatment. [Extracted from the article]

A recent study conducted by investigators from Wuhan Polytechnic University in China has explored the use of gold nanoparticles for the photothermal treatment of bacterial infections. Traditional photothermal therapy (PTT) can cause damage to surrounding normal tissues, limiting its effectiveness. The researchers developed an acid-responsive PTT system using gold nanoparticles that can precisely kill bacteria without harming normal tissues. This strategy shows promise for combating bacterial infections. The study has been peer-reviewed and published in ACS Infectious Diseases. [Extracted from the article]

A recent study conducted at Wuhan University in China has explored the potential of sonodynamic therapy (SDT) in cancer treatment. SDT has shown promise in its ability to penetrate tissues with minimal damage to healthy cells, but its effectiveness is limited by the complex immunological environment and resistance of tumors to treatment. The researchers proposed a tumor-targeted nanomachine that uses ultrasound to generate mechanical damage to lysosomes in cancer cells. This approach resulted in cell death and reprogramming of tumor-associated macrophages to an antitumor phenotype. The study suggests a new direction for cancer treatment by combining mechanical destruction with immunotherapy. [Extracted from the article]

Wuhan, People's Republic of China, Asia, Emerging Technologies, Enterobacteriaceae, Foodborne Diseases and Conditions, Gammaproteobacteria, Gold Nanoparticles, Gram-Negative Bacteria, Gram-Negative Facultatively Anaerobic Rods, Nanoparticles, Nanotechnology, Proteobacteria, Salmonella Keywords: Wuhan; People's Republic of China; Asia; Emerging Technologies; Enterobacteriaceae; Foodborne Diseases and Conditions; Gammaproteobacteria; Gold Nanoparticles; Gram-Negative Bacteria; Gram-Negative Facultatively Anaerobic Rods; Nanoparticles; Nanotechnology; Proteobacteria; Salmonella EN Wuhan People's Republic of China Asia Emerging Technologies Enterobacteriaceae Foodborne Diseases and Conditions Gammaproteobacteria Gold Nanoparticles Gram-Negative Bacteria Gram-Negative Facultatively Anaerobic Rods Nanoparticles Nanotechnology Proteobacteria Salmonella 62 62 1 07/10/23 20230713 NES 230713 2023 JUL 13 (NewsRx) -- By a News Reporter-Staff News Editor at Food Weekly News -- New research on Gram-Negative Bacteria - Salmonella is the subject of a report. [Extracted from the article]

Keywords: Wuhan; People's Republic of China; Asia; Drugs and Therapies; Emerging Technologies; Gold Nanoparticles; Nanoparticles; Nanotechnology EN Wuhan People's Republic of China Asia Drugs and Therapies Emerging Technologies Gold Nanoparticles Nanoparticles Nanotechnology 593 593 1 05/29/23 20230602 NES 230602 2023 JUN 2 (NewsRx) -- By a News Reporter-Staff News Editor at Drug Week -- Researchers detail new data in Nanotechnology - Gold Nanoparticles. Wuhan, People's Republic of China, Asia, Drugs and Therapies, Emerging Technologies, Nanoparticles, Nanotechnology, Gold Nanoparticles. [Extracted from the article]

Keywords: Wuhan; People's Republic of China; Asia; Antidiabetic Agents; Biguanides; Drugs and Therapies; Emerging Technologies; Gold Nanoparticles; Health and Medicine; Hypoglycemic Agents; Metformin; Metformin Therapy; Nanoconjugates; Nanoparticles; Nanotechnology; Non-Sulfonylureas; Pharmaceuticals; Therapy EN Wuhan People's Republic of China Asia Antidiabetic Agents Biguanides Drugs and Therapies Emerging Technologies Gold Nanoparticles Health and Medicine Hypoglycemic Agents Metformin Metformin Therapy Nanoconjugates Nanoparticles Nanotechnology Non-Sulfonylureas Pharmaceuticals Therapy 500 500 1 05/02/23 20230505 NES 230505 2023 MAY 5 (NewsRx) -- By a News Reporter-Staff News Editor at Drug Week -- A new study on Nanotechnology - Gold Nanoparticles is now available. According to the news editors, the research concluded: "Together with good targeting ability of tumor microenvironments and good biocompatibility, this work provides a potential drug candidate for the mild chemo-photothermal synergistic therapy for tumors.". [Extracted from the article]