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169 results on '"Bennink, Roel J."'

1. Adjuvant holmium-166 radioembolization after radiofrequency ablation in early-stage hepatocellular carcinoma patients: a dose-finding study (HORA EST HCC trial)

Author

Hendriks, Pim, Rietbergen, Daphne D. D., van Erkel, Arian R., Coenraad, Minneke J., Arntz, Mark J., Bennink, Roel J., Braat, Andries E., Crobach, Stijn, van Delden, Otto M., Dibbets-Schneider, Petra, van der Hulle, Tom, Klümpen, Heinz-Josef, van der Meer, Rutger W., Nijsen, J. Frank W., van Rijswijk, Catharina S. P., Roosen, Joey, Ruijter, Bastian N., Smit, Frits, Stam, Mette K., Takkenberg, R. Bart, Tushuizen, Maarten E., van Velden, Floris H. P., de Geus-Oei, Lioe-Fee, and Burgmans, Mark C.

Published
2024
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2. Extrahepatic perfusion and incomplete hepatic perfusion after hepatic arterial infusion pump implantation: incidence and clinical implications

Author

Filipe, Wills F., Buisman, Florian Buismanz, Koerkamp, Bas Groot, Grunhagen, Dirk J., Homs, Marjolein Y.V., Verhoef, Cornelis, Moelker, Adriaan, Graven, Laura, Franssen, Stijn, Gobardhan, Paul D., Loosveld, Olaf J.L., Pool, Stefan, Mieog, J. Sven D., Speetjens, Frank M., Rietbergen, Daphne D.D., Burgmans, Mark C., Doornesbosch, Pascal G., Patijn, Gijs A., de Groot, Jan Willem B., Meier, Mark A.J., Oostdijk, Ad H.J., Boluis, Karen, Grootscholten, Cecile, klompenhouwer, Elizabeth G., Kok, Niels F.M., kuhlmann, Koert, F.D., Krul, Myrtle F., Versleijen, Michelle W.J., Bruijnen, Rutger C.G., Hagendoorn, Jroen, Lam, Marnix G.E.H., Roodhart, Jeanine M.L., Bennink, Roel J., van Delden, Otto M., Swijnenburg, Rutger-Jan, Buffart, Tineke E., Borel Rinkes, Inne H.M., Cercek, Andrea, Kemeny, Nancy E., Peter Kingham, T., D’Angelica, Michael, van Bommel, Christian P.H., van Doorn, Leni, Ayez, Ninos, Vermaas, Maarten, Nieuwenhuijse, Vincent B., Buisman, Florian E., Grünhagen, Dirk J., Bolhuis, Karen, Doornebosch, Pascal G., Hagendoorn, Jeroen, Harmsen, Paul, Klompenhouwer, Elizabeth G., Outmani, Loubna, Swijnenburg, Rutger Jan, Kuhlmann, Koert F.D., and Groot Koerkamp, Bas

Published
2024
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3. Dose finding study for unilobar radioembolization using holmium-166 microspheres to improve resectability in patients with HCC: the RALLY protocol

Author

Andel, Daan, Lam, Marnix G. E. H., de Bruijne, Joep, Smits, Maarten L. J., Braat, Arthur J. A. T., Moelker, Adriaan, Vegt, Erik, Ruiter, Simeon J. S., Noordzij, Walter, Grazi, Gianluca, Vallati, Giulio E., Bennink, Roel J., van Delden, Otto M., Kranenburg, Onno W., Ijzermans, Jan N. M., Nijkamp, Maarten W., Erdmann, Joris I., Sciuto, Rosa, Hagendoorn, Jeroen, and Borel Rinkes, Inne H. M.

Published
2023
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4. De impact van de nucleaire geneeskunde

Author

Zonneveld, Abigail J. E., Kaldeway, Peter, Smit Duijzentkunst, Daan A., Kwekkeboom, Dik J., Bennink, Roel J., Maas, Mario, editor, Nusman, Charlotte, editor, Smithuis, Frank, editor, and Bennink, Roel, editor

Published
2023
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5. Interventieradiologie

Author

van Delden, Otto M., Schreuder, Sanne M., Bennink, Roel J., Lam, Marnix G. E. H., Maas, Mario, editor, Nusman, Charlotte, editor, Smithuis, Frank, editor, and Bennink, Roel, editor

Published
2023
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9. Study Protocol: Adjuvant Holmium-166 Radioembolization After Radiofrequency Ablation in Early-Stage Hepatocellular Carcinoma Patients—A Dose-Finding Study (HORA EST HCC Trial)

Author

Hendriks, Pim, Rietbergen, Daphne D. D., van Erkel, Arian R., Coenraad, Minneke J., Arntz, Mark J., Bennink, Roel J., Braat, Andries E., Crobach, A. Stijn L. P., van Delden, Otto M., van der Hulle, Tom, Klümpen, Heinz-Josef, van der Meer, Rutger W., Nijsen, J. Frank W., van Rijswijk, Carla S. P., Roosen, Joey, Ruijter, Bastian N., Smit, Frits, Stam, Mette K., Takkenberg, R. Bart, Tushuizen, Maarten E., van Velden, Floris H. P., de Geus-Oei, Lioe-Fee, and Burgmans, Mark C.

Published
2022
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11. Extrahepatic perfusion and incomplete hepatic perfusion after hepatic arterial infusion pump implantation:incidence and clinical implications

Author

Filipe, Wills F, Buisman, Florian E, Franssen, Stijn, Krul, Myrtle F, Grünhagen, Dirk J, Bennink, Roel J, Bolhuis, Karen, Bruijnen, Rutger C G, Buffart, Tineke E, Burgmans, Mark C, van Delden, Otto M, Doornebosch, Pascal G, Gobardhan, Paul D, Graven, Laura, de Groot, Jan Willem B, Grootscholten, Cecile, Hagendoorn, Jeroen, Harmsen, Paul, Homs, Marjolein Y V, Klompenhouwer, Elizabeth G, Kok, Niels F M, Lam, Marnix G E H, Loosveld, Olaf J L, Meier, Mark A J, Mieog, J Sven D, Oostdijk, Ad H J, Outmani, Loubna, Patijn, Gijs A, Pool, Stefan, Rietbergen, Daphne D D, Roodhart, Jeanine M L, Speetjens, Frank M, Swijnenburg, Rutger Jan, Versleijen, Michelle W J, Verhoef, Cornelis, Kuhlmann, Koert F D, Moelker, Adriaan, Groot Koerkamp, Bas, Filipe, Wills F, Buisman, Florian E, Franssen, Stijn, Krul, Myrtle F, Grünhagen, Dirk J, Bennink, Roel J, Bolhuis, Karen, Bruijnen, Rutger C G, Buffart, Tineke E, Burgmans, Mark C, van Delden, Otto M, Doornebosch, Pascal G, Gobardhan, Paul D, Graven, Laura, de Groot, Jan Willem B, Grootscholten, Cecile, Hagendoorn, Jeroen, Harmsen, Paul, Homs, Marjolein Y V, Klompenhouwer, Elizabeth G, Kok, Niels F M, Lam, Marnix G E H, Loosveld, Olaf J L, Meier, Mark A J, Mieog, J Sven D, Oostdijk, Ad H J, Outmani, Loubna, Patijn, Gijs A, Pool, Stefan, Rietbergen, Daphne D D, Roodhart, Jeanine M L, Speetjens, Frank M, Swijnenburg, Rutger Jan, Versleijen, Michelle W J, Verhoef, Cornelis, Kuhlmann, Koert F D, Moelker, Adriaan, and Groot Koerkamp, Bas

Abstract

INTRODUCTION: This study investigates the incidence of extrahepatic perfusion and incomplete hepatic perfusion at intraoperative methylene blue testing and on postoperative nuclear imaging in patients undergoing hepatic arterial infusion pump (HAIP) chemotherapy.METHODS:The first 150 consecutive patients who underwent pump implantation in the Netherlands were included. All patients underwent surgical pump implantation with the catheter in the gastroduodenal artery. All patients underwent intraoperative methylene blue testing and postoperative nuclear imaging ( 99mTc-Macroaggregated albumin SPECT/CT) to determine perfusion via the pump. RESULTS: Patients were included between January-2018 and December-2021 across eight centers. During methylene blue testing, 29.3% had extrahepatic perfusion, all successfully managed intraoperatively. On nuclear imaging, no clinically relevant extrahepatic perfusion was detected (0%, 95%CI: 0.0-2.5%). During methylene blue testing, 2.0% had unresolved incomplete hepatic perfusion. On postoperative nuclear imaging, 8.1% had incomplete hepatic perfusion, leading to embolization in only 1.3%.CONCLUSION: Methylene blue testing during pump placement for intra-arterial chemotherapy identified extrahepatic perfusion in 29.3% of patients, but could be resolved intraoperatively in all patients. Postoperative nuclear imaging found no clinically relevant extrahepatic perfusion and led to embolization in only 1.3% of patients. The role of routine nuclear imaging after HAIP implantation should be studied in a larger cohort.

Published
2024

13. Active Surveillance Versus Immediate Surgery in Clinically Complete Responders After Neoadjuvant Chemoradiotherapy for Esophageal Cancer: A Multicenter Propensity Matched Study

Author

van der Wilk, Berend J., Noordman, Bo J., Neijenhuis, Lisanne K. A., Nieboer, Daan, Nieuwenhuijzen, Grard A. P., Sosef, Meindert N., van Berge Henegouwen, Mark I., Lagarde, Sjoerd M., Spaander, Manon C. W., Valkema, Roelf, Biermann, Katharina, Wijnhoven, Bas P. L., van der Gaast, Ate, van Lanschot, J. Jan B., Doukas, Michael, Nikkessen, Suzan, Luyer, Misha, Schoon, Erik J., Roef, Mark J., van Lijnschoten, Ineke, Oostenbrug, Liekele E., Riedl, Robert G., Gisbertz, Suzanne S., Krishnadath, Kausilia K., Bennink, Roel J., and Meijer, Sybren L.

Published
2021
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15. External validation of 18F-FDG PET-based radiomic models on identification of residual oesophageal cancer after neoadjuvant chemoradiotherapy

Author

Valkema, Maria J., primary, Beukinga, Roelof J., additional, Chatterjee, Avishek, additional, Woodruff, Henry C., additional, van Klaveren, David, additional, Noordzij, Walter, additional, Valkema, Roelf, additional, Bennink, Roel J., additional, Roef, Mark J., additional, Schreurs, Wendy, additional, Doukas, Michail, additional, Lagarde, Sjoerd M., additional, Wijnhoven, Bas P.L., additional, Lambin, Philippe, additional, Plukker, John T.M., additional, and van Lanschot, J. Jan B., additional

Published
2023
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16. External validation of 18F-FDG PET-based radiomic models on identification of residual oesophageal cancer after neoadjuvant chemoradiotherapy

Author

Valkema, Maria J., Beukinga, Roelof J., Chatterjee, Avishek, Woodruff, Henry C., Van Klaveren, David, Noordzij, Walter, Valkema, Roelf, Bennink, Roel J., Roef, Mark J., Schreurs, Wendy, Doukas, Michail, Lagarde, Sjoerd M., Wijnhoven, Bas P.L., Lambin, Philippe, Plukker, John T.M., Van Lanschot, J. Jan B., Valkema, Maria J., Beukinga, Roelof J., Chatterjee, Avishek, Woodruff, Henry C., Van Klaveren, David, Noordzij, Walter, Valkema, Roelf, Bennink, Roel J., Roef, Mark J., Schreurs, Wendy, Doukas, Michail, Lagarde, Sjoerd M., Wijnhoven, Bas P.L., Lambin, Philippe, Plukker, John T.M., and Van Lanschot, J. Jan B.

Abstract

Objectives Detection of residual oesophageal cancer after neoadjuvant chemoradiotherapy (nCRT) is important to guide treatment decisions regarding standard oesophagectomy or active surveillance. The aim was to validate previously developed 18F-FDG PET-based radiomic models to detect residual local tumour and to repeat model development (i.e. 'model extension') in case of poor generalisability. Methods This was a retrospective cohort study in patients collected from a prospective multicentre study in four Dutch institutes. Patients underwent nCRT followed by oesophagectomy between 2013 and 2019. Outcome was tumour regression grade (TRG) 1 (0% tumour) versus TRG 2-3-4 (≥1% tumour). Scans were acquired according to standardised protocols. Discrimination and calibration were assessed for the published models with optimism-corrected AUCs >0.77. For model extension, the development and external validation cohorts were combined. Results Baseline characteristics of the 189 patients included [median age 66 years (interquartile range 60-71), 158/189 male (84%), 40/189 TRG 1 (21%) and 149/189 (79%) TRG 2-3-4] were comparable to the development cohort. The model including cT stage plus the feature 'sum entropy' had best discriminative performance in external validation (AUC 0.64, 95% confidence interval 0.55-0.73), with a calibration slope and intercept of 0.16 and 0.48 respectively. An extended bootstrapped LASSO model yielded an AUC of 0.65 for TRG 2-3-4 detection. Conclusion The high predictive performance of the published radiomic models could not be replicated. The extended model had moderate discriminative ability. The investigated radiomic models appeared inaccurate to detect local residual oesophageal tumour and cannot be used as an adjunct tool for clinical decision-making in patients.

Published
2023

17. Dose finding study for unilobar radioembolization using holmium-166 microspheres to improve resectability in patients with HCC:the RALLY protocol

Author

Andel, Daan, Lam, Marnix G.E.H., de Bruijne, Joep, Smits, Maarten L.J., Braat, Arthur J.A.T., Moelker, Adriaan, Vegt, Erik, Ruiter, Simeon J.S., Noordzij, Walter, Grazi, Gianluca, Vallati, Giulio E., Bennink, Roel J., van Delden, Otto M., Kranenburg, Onno W., Ijzermans, Jan N.M., Nijkamp, Maarten W., Erdmann, Joris I., Sciuto, Rosa, Hagendoorn, Jeroen, Borel Rinkes, Inne H.M., Andel, Daan, Lam, Marnix G.E.H., de Bruijne, Joep, Smits, Maarten L.J., Braat, Arthur J.A.T., Moelker, Adriaan, Vegt, Erik, Ruiter, Simeon J.S., Noordzij, Walter, Grazi, Gianluca, Vallati, Giulio E., Bennink, Roel J., van Delden, Otto M., Kranenburg, Onno W., Ijzermans, Jan N.M., Nijkamp, Maarten W., Erdmann, Joris I., Sciuto, Rosa, Hagendoorn, Jeroen, and Borel Rinkes, Inne H.M.

Abstract

Background: High dose unilobar radioembolization (also termed ‘radiation lobectomy’)—the transarterial unilobar infusion of radioactive microspheres as a means of controlling tumour growth while concomitantly inducing future liver remnant hypertrophy—has recently gained interest as induction strategy for surgical resection. Prospective studies on the safety and efficacy of the unilobar radioembolization-surgery treatment algorithm are lacking. The RALLY study aims to assess the safety and toxicity profile of holmium-166 unilobar radioembolization in patients with hepatocellular carcinoma ineligible for surgery due to insufficiency of the future liver remnant. Methods: The RALLY study is a multicenter, interventional, non-randomized, open-label, non-comparative safety study. Patients with hepatocellular carcinoma who are considered ineligible for surgery due to insufficiency of the future liver remnant (< 2.7%/min/m2 on hepatobiliary iminodiacetic acid scan will be included. A classical 3 + 3 dose escalation model will be used, enrolling three to six patients in each cohort. The primary objective is to determine the maximum tolerated treated non-tumourous liver-absorbed dose (cohorts of 50, 60, 70 and 80 Gy). Secondary objectives are to evaluate dose–response relationships, to establish the safety and feasibility of surgical resection following unilobar radioembolization, to assess quality of life, and to generate a biobank. Discussion: This will be the first clinical study to assess the unilobar radioembolization-surgery treatment algorithm and may serve as a stepping stone towards its implementation in routine clinical practice. Trial registration: Netherlands Trial Register NL8902 , registered on 2020–09-15.

Published
2023

18. Dose finding study for unilobar radioembolization using holmium-166 microspheres to improve resectability in patients with HCC: the RALLY protocol

Author

MS HOD, Lab Translational Oncology, Researchgr. Nucleaire Geneeskunde, Cancer, MS MDL 1, MS Radiologie, Regenerative Medicine and Stem Cells, MS CGO, Andel, Daan, Lam, Marnix G.E.H., de Bruijne, Joep, Smits, Maarten L.J., Braat, Arthur J.A.T., Moelker, Adriaan, Vegt, Erik, Ruiter, Simeon J.S., Noordzij, Walter, Grazi, Gianluca, Vallati, Giulio E., Bennink, Roel J., van Delden, Otto M., Kranenburg, Onno W., Ijzermans, Jan N.M., Nijkamp, Maarten W., Erdmann, Joris I., Sciuto, Rosa, Hagendoorn, Jeroen, Borel Rinkes, Inne H.M., MS HOD, Lab Translational Oncology, Researchgr. Nucleaire Geneeskunde, Cancer, MS MDL 1, MS Radiologie, Regenerative Medicine and Stem Cells, MS CGO, Andel, Daan, Lam, Marnix G.E.H., de Bruijne, Joep, Smits, Maarten L.J., Braat, Arthur J.A.T., Moelker, Adriaan, Vegt, Erik, Ruiter, Simeon J.S., Noordzij, Walter, Grazi, Gianluca, Vallati, Giulio E., Bennink, Roel J., van Delden, Otto M., Kranenburg, Onno W., Ijzermans, Jan N.M., Nijkamp, Maarten W., Erdmann, Joris I., Sciuto, Rosa, Hagendoorn, Jeroen, and Borel Rinkes, Inne H.M.

Published
2023

19. Feasibility and Safety of Tailored Lymphadenectomy Using Sentinel Node-Navigated Surgery in Patients with High-Risk T1 Esophageal Adenocarcinoma

Author

Unit Opleiding Aios, Cancer, MS MDL 1, MS Radiologie, Pathologie Pathologen staf, MS CGO, Frederiks, Charlotte N, Overwater, Anouk, Bergman, Jacques J G H M, Pouw, Roos E, de Keizer, Bart, Bennink, Roel J, Brosens, Lodewijk A A, Meijer, Sybren L, van Hillegersberg, Richard, van Berge Henegouwen, Mark I, Ruurda, Jelle P, Gisbertz, Suzanne S, Weusten, Bas L A M, Unit Opleiding Aios, Cancer, MS MDL 1, MS Radiologie, Pathologie Pathologen staf, MS CGO, Frederiks, Charlotte N, Overwater, Anouk, Bergman, Jacques J G H M, Pouw, Roos E, de Keizer, Bart, Bennink, Roel J, Brosens, Lodewijk A A, Meijer, Sybren L, van Hillegersberg, Richard, van Berge Henegouwen, Mark I, Ruurda, Jelle P, Gisbertz, Suzanne S, and Weusten, Bas L A M

Published
2023

21. Distribution of lymph node metastases in esophageal carcinoma [TIGER study]: study protocol of a multinational observational study

Author

Hagens, Eliza R. C., van Berge Henegouwen, Mark I., van Sandick, Johanna W., Cuesta, Miguel A., van der Peet, Donald L., Heisterkamp, Joos, Nieuwenhuijzen, Grard A. P., Rosman, Camiel, Scheepers, Joris J. G., Sosef, Meindert N., van Hillegersberg, Richard, Lagarde, Sjoerd M., Nilsson, Magnus, Räsänen, Jari, Nafteux, Philippe, Pattyn, Piet, Hölscher, Arnulf H., Schröder, Wolfgang, Schneider, Paul M., Mariette, Christophe, Castoro, Carlo, Bonavina, Luigi, Rosati, Riccardo, de Manzoni, Giovanni, Mattioli, Sandro, Garcia, Josep Roig, Pera, Manuel, Griffin, Michael, Wilkerson, Paul, Chaudry, M. Asif, Sgromo, Bruno, Tucker, Olga, Cheong, Edward, Moorthy, Krishna, Walsh, Thomas N., Reynolds, John, Tachimori, Yuji, Inoue, Haruhiro, Matsubara, Hisahiro, Kosugi, Shin-ichi, Chen, Haiquan, Law, Simon Y. K., Pramesh, C. S., Puntambekar, Shailesh P., Murthy, Sudish, Linden, Philip, Hofstetter, Wayne L., Kuppusamy, Madhan K., Shen, K. Robert, Darling, Gail E., Sabino, Flávio D., Grimminger, Peter P., Meijer, Sybren L., Bergman, Jacques J. G. H. M., Hulshof, Maarten C. C. M., van Laarhoven, Hanneke W. M., Mearadji, Banafsche, Bennink, Roel J., Annema, Jouke T., Dijkgraaf, Marcel G. W., and Gisbertz, Suzanne S.

Published
2019
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22. External validation of 18F-FDG PET-based radiomic models on identification of residual oesophageal cancer after neoadjuvant chemoradiotherapy.

Author

Valkema, Maria J., Beukinga, Roelof J., Chatterjee, Avishek, Woodruff, Henry C., Klaveren, David van, Noordzij, Walter, Valkema, Roelf, Bennink, Roel J., Roef, Mark J., Schreurs, Wendy, Doukas, Michail, Lagardea, Sjoerd M., Wijnhoven, Bas P. L., Lambin, Philippe, Plukker, John T. M., and van Lanschot, J. Jan B.

Published
2023
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24. Increased Hepatic Microvascular Density, Oxygenation, and VEGF in the Hypertrophic Lobe following Portal Vein Embolization in Rabbits

Author

Uz, Zuhre, Ergin, Bulent, Shen, Lucinda, van Lienden, Krijn P., Rassam, Fadi, Olthof, Pim B., Bennink, Roel J., Ince, Can, van Gulik, Thomas M., Uz, Zuhre, Ergin, Bulent, Shen, Lucinda, van Lienden, Krijn P., Rassam, Fadi, Olthof, Pim B., Bennink, Roel J., Ince, Can, and van Gulik, Thomas M.

Abstract

Introduction: The microvascular events following portal vein embolization (PVE) are poorly understood despite the pivotal role of the microcirculation in liver regeneration and tumor progression. We aimed to assess the changes in hepatic microvascular perfusion and neo-angiogenesis after experimental PVE. Methods: PVE of the cranial liver lobes was performed in 12 New Zealand White rabbits divided into 2 groups of permanent (P-PVE) and reversible PVE (R-PVE), respectively. Hepatobiliary scintigraphy and CT were used to evaluate hepatic function and volume. Hepatic microcirculation was assessed using a handheld vital microscope (Cytocam) to measure microvascular density (total vessel density; TVD) before PVE, right after PVE, and 20 min after PVE, as well as at 14 days (D14 post-PVE) and 35 days (D35 post-PVE). Additionally, on D35, microvascular PO and liver parenchymal VEGF were assessed. Results: Eleven rabbits were included after PVE (R-PVE, n = 5; P-PVE, n = 6). TVD in the nonembo-lized (hypertrophic) lobes was higher than in the embolized (atrophic) lobes of the P-PVE group at D35 post-PVE (36.7 ± 7.2 vs. 23.4 ± 4.9 mm/mm p < 0.05). In the R-PVE group, TVD in the nonembolized lobes was not increased at D35. Function and volume were increased in the nonembolized lobes of the P-PVE group compared to the embolized lobes, but not in the R-PVE group. Likewise, the mmicrovascular PO2 and VEGF staining rate were higher in the nonembolized lobes of the P-PVE group at D35 post-PVE. Discussion/Conclusion: Successful volumetric and functional hypertrophy of the nonembolized lobe was accompanied by microvascular alterations featuring increased neo-angiogenesis, microvascular density, and microvascular oxygen pressure following P-PVE.

Published
2022

25. Feasibility of sentinel node navigated surgery in high-risk T1b esophageal adenocarcinoma patients using a hybrid tracer of technetium-99 m and indocyanine green

Author

MS MDL 1, Cancer, MS CGO, MS Radiologie, Pathologie Pathologen staf, Overwater, Anouk, Weusten, Bas L A M, Ruurda, Jelle P, van Hillegersberg, Richard, Bennink, Roel J, de Keizer, Bart, Meijer, Sybren L, Brosens, Lodewijk A A, Pouw, Roos E, Bergman, Jacques J G H M, van Berge Henegouwen, Mark I, Gisbertz, Suzanne S, MS MDL 1, Cancer, MS CGO, MS Radiologie, Pathologie Pathologen staf, Overwater, Anouk, Weusten, Bas L A M, Ruurda, Jelle P, van Hillegersberg, Richard, Bennink, Roel J, de Keizer, Bart, Meijer, Sybren L, Brosens, Lodewijk A A, Pouw, Roos E, Bergman, Jacques J G H M, van Berge Henegouwen, Mark I, and Gisbertz, Suzanne S

Published
2022

28. Liver Decompensation as Late Complication in HCC Patients with Long-Term Response following Selective Internal Radiation Therapy

Author

van Doorn, Diederick J., primary, Hendriks, Pim, additional, Burgmans, Mark C., additional, Rietbergen, Daphne D. D., additional, Coenraad, Minneke J., additional, van Delden, Otto M., additional, Bennink, Roel J., additional, Labeur, Tim A., additional, Klümpen, Heinz-Josef, additional, Eskens, Ferry A. L. M., additional, Moelker, Adriaan, additional, Vegt, Erik, additional, Sprengers, Dave, additional, Mostafavi, Nahid, additional, Ijzermans, Jan, additional, and Takkenberg, R. Bart, additional

Published
2021
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32. Liver decompensation as late complication in hcc patients with long-term response following selective internal radiation therapy

Author

van Doorn, Diederick J., Hendriks, Pim, Burgmans, Mark C., Rietbergen, Daphne D.D., Coenraad, Minneke J., van Delden, Otto M., Bennink, Roel J., Labeur, Tim A., Klümpen, Heinz Josef, Eskens, Ferry A.L.M., Moelker, Adriaan, Vegt, Erik, Sprengers, Dave, Mostafavi, Nahid, Ijzermans, Jan, Takkenberg, R. Bart, van Doorn, Diederick J., Hendriks, Pim, Burgmans, Mark C., Rietbergen, Daphne D.D., Coenraad, Minneke J., van Delden, Otto M., Bennink, Roel J., Labeur, Tim A., Klümpen, Heinz Josef, Eskens, Ferry A.L.M., Moelker, Adriaan, Vegt, Erik, Sprengers, Dave, Mostafavi, Nahid, Ijzermans, Jan, and Takkenberg, R. Bart

Abstract

Selective internal radiation therapy (SIRT) is used as a treatment for hepatocellular carcinoma (HCC). The aim of this study was to assess long-term liver-related complications of SIRT in patients who had not developed radioembolization-induced liver disease (REILD). The primary outcome was the percentage of patients without REILD that developed Child-Pugh (CP) ≥ B7 liver decompensation after SIRT. The secondary outcomes were overall survival (OS) and tumor response. These data were compared with a matched cohort of patients treated with sorafenib. Eighty-five patients were included, of whom 16 developed REILD. Of the remaining 69 patients, 38 developed liver decompensation CP ≥ B7. The median OS was 18 months. In patients without REILD, the median OS in patients with CP ≥ B7 was significantly shorter compared to those without CP ≥ B7; 16 vs. 31 months. In the case-matched analysis, the median OS was significantly longer in SIRT-treated patients; 16 vs. 8 months in sorafenib. Liver decompensation CP ≥ B7 occurred significantly more in SIRT when compared to sorafenib; 62% vs. 27%. The ALBI score was an independent predictor of liver decompensation (OR 0.07) and OS (HR 2.83). After SIRT, liver decompensation CP ≥ B7 often developed as a late complication in HCC patients and was associated with a shorter OS. The ALBI score was predictive of CP ≥ B7 liver decompensation and the OS, and this may be a valuable marker for patient selection for SIRT.

Published
2021

33. [18F]FDG and [18F]FES positron emission tomography for disease monitoring and assessment of anti-hormonal treatment eligibility in granulosa cell tumors of the ovary

Author

MS Gynaecologische Oncologie, Genetica Groep Van Haaften, MS Radiologie, Circulatory Health, Cancer, Arts-assistenten DV&B, MS Medische Oncologie, Pathologie Pathologen staf, Roze, Joline F, van Meurs, Hannah S, Monroe, Glen R, Veldhuis, Wouter B, van Lonkhuijzen, Luc R C W, Bennink, Roel J, Groeneweg, Jolijn W, Witteveen, Petronella O, Jonges, Geertruida N, Zweemer, Ronald P, Braat, Arthur J A T, MS Gynaecologische Oncologie, Genetica Groep Van Haaften, MS Radiologie, Circulatory Health, Cancer, Arts-assistenten DV&B, MS Medische Oncologie, Pathologie Pathologen staf, Roze, Joline F, van Meurs, Hannah S, Monroe, Glen R, Veldhuis, Wouter B, van Lonkhuijzen, Luc R C W, Bennink, Roel J, Groeneweg, Jolijn W, Witteveen, Petronella O, Jonges, Geertruida N, Zweemer, Ronald P, and Braat, Arthur J A T

Published
2021

35. Feasibility of sentinel node navigated surgery in high-risk T1b esophageal adenocarcinoma patients using a hybrid tracer of technetium-99 m and indocyanine green

Author

Overwater, Anouk, primary, Weusten, Bas L. A. M., additional, Ruurda, Jelle P., additional, van Hillegersberg, Richard, additional, Bennink, Roel J., additional, de Keizer, Bart, additional, Meijer, Sybren L., additional, Brosens, Lodewijk A. A., additional, Pouw, Roos E., additional, Bergman, Jacques J. G. H. M., additional, van Berge Henegouwen, Mark I., additional, and Gisbertz, Suzanne S., additional

Published
2021
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36. [18F]FDG and [18F]FES positron emission tomography for disease monitoring and assessment of anti-hormonal treatment eligibility in granulosa cell tumors of the ovary

Author

Roze, Joline F., primary, van Meurs, Hannah S., additional, Monroe, Glen R., additional, Veldhuis, Wouter B., additional, van Lonkhuijzen, Luc R.C.W., additional, Bennink, Roel J., additional, Groeneweg, Jolijn W., additional, Witteveen, Petronella O., additional, Jonges, Geertruida N., additional, Zweemer, Ronald P., additional, and Braat, Arthur J.A.T., additional

Published
2021
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37. FEASIBILITY OF SENTINEL NODE NAVIGATION SURGERY IN PATIENTS WITH HIGH-RISK SUBMUCOSAL (T1B) ESOPHAGEAL ADENOCARCINOMA USING A HYBRID TRACER OF TECHNETIUM-99M AND INDOCYANINE GREEN

Author

MS MDL 1, Cancer, MS CGO, MS Radiologie, Pathologie Pathologen staf, Overwater, Anouk, Weusten, Bas L., Ruurda, Jelle, van Hillegersberg, R., Bennink, Roel J., de Keizer, Bart, Meijer, Sybren L., Brosens, Lodewijk A., Pouw, Roos E., Bergman, Jacques, Henegouwen, Mark I. van Berge, Gisbertz, Suzanne, MS MDL 1, Cancer, MS CGO, MS Radiologie, Pathologie Pathologen staf, Overwater, Anouk, Weusten, Bas L., Ruurda, Jelle, van Hillegersberg, R., Bennink, Roel J., de Keizer, Bart, Meijer, Sybren L., Brosens, Lodewijk A., Pouw, Roos E., Bergman, Jacques, Henegouwen, Mark I. van Berge, and Gisbertz, Suzanne

Published
2020

38. The utility of 99mTc-mebrofenin hepatobiliary scintigraphy with SPECT/CT for selective internal radiation therapy in hepatocellular carcinoma

Author

Fysica Radiologie, Researchgr. Nucleaire Geneeskunde, Cancer, Labeur, Tim A, Cieslak, Kasia P, Van Gulik, Thomas M, Takkenberg, R Bart, van der Velden, Sandra, Lam, Marnix G E H, Klümpen, Heinz-Josef, Bennink, Roel J, van Delden, Otto M, Fysica Radiologie, Researchgr. Nucleaire Geneeskunde, Cancer, Labeur, Tim A, Cieslak, Kasia P, Van Gulik, Thomas M, Takkenberg, R Bart, van der Velden, Sandra, Lam, Marnix G E H, Klümpen, Heinz-Josef, Bennink, Roel J, and van Delden, Otto M

Published
2020

39. 323 FEASIBILITY AND SAFETY OF TAILORED LYMPHADENECTOMY USING SENTINEL NODE NAVIGATED SURGERY WITH A HYBRID TRACER OF TECHNETIUM-99M AND INDOCYANINE GREEN IN HIGH-RISK T1 ESOPHAGEAL ADENOCARCINOMA PATIENTS

Author

Frederiks, Charlotte, Overwater, Anouk, Bergman, Jacques, Pouw, Roos E., De Keizer, Bart, Bennink, Roel J., Brosens, Lodewijk A., Meijer, Sybren L., van Hillegersberg, Richard, Van Berge Henegouwen, Mark I., Ruurda, Jelle, Gisbertz, Suzanne S., and Weusten, Bas L.

Published
2023
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41. Sa1235 FEASIBILITY OF SENTINEL NODE NAVIGATION SURGERY IN PATIENTS WITH HIGH-RISK SUBMUCOSAL (T1B) ESOPHAGEAL ADENOCARCINOMA USING A HYBRID TRACER OF TECHNETIUM-99M AND INDOCYANINE GREEN

Author

Overwater, Anouk, primary, Weusten, Bas L., additional, Ruurda, Jelle, additional, van Hillegersberg, R., additional, Bennink, Roel J., additional, de Keizer, Bart, additional, Meijer, Sybren L., additional, Brosens, Lodewijk A., additional, Pouw, Roos E., additional, Bergman, Jacques, additional, van Berge Henegouwen, Mark I., additional, and Gisbertz, Suzanne, additional

Published
2020
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42. Comparison of functional and volumetric increase of the future remnant liver and postoperative outcomes after portal vein embolization and complete or partial associating liver partition and portal vein ligation for staged hepatectomy (ALPPS)

Author

Rassam, Fadi, primary, Olthof, Pim B., additional, Lienden, Krijn P. van, additional, Bennink, Roel J., additional, Erdmann, Joris I., additional, Swijnenburg, Rutger-Jan, additional, Busch, Olivier R., additional, Besselink, Marc G., additional, and van Gulik, Thomas M., additional

Published
2020
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43. Phase II Feasibility and Biomarker Study of Neoadjuvant Trastuzumab and Pertuzumab With Chemoradiotherapy for Resectable Human Epidermal Growth Factor Receptor 2–Positive Esophageal Adenocarcinoma: TRAP Study

Author

Stroes, Charlotte I., primary, Schokker, Sandor, additional, Creemers, Aafke, additional, Molenaar, Remco J., additional, Hulshof, Maarten C.C.M., additional, van der Woude, Stephanie O., additional, Bennink, Roel J., additional, Mathôt, Ron A.A., additional, Krishnadath, Kausilia K., additional, Punt, Cornelis J.A., additional, Verhoeven, Rob H.A., additional, van Oijen, Martijn G.H., additional, Creemers, Geert-Jan, additional, Nieuwenhuijzen, Grard A.P., additional, van der Sangen, Maurice J.C., additional, Beerepoot, Laurens V., additional, Heisterkamp, Joos, additional, Los, Maartje, additional, Slingerland, Marije, additional, Cats, Annemieke, additional, Hospers, Geke A.P., additional, Bijlsma, Maarten F., additional, van Berge Henegouwen, Mark I., additional, Meijer, Sybren L., additional, and van Laarhoven, Hanneke W.M., additional

Published
2020
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45. Distribution of lymph node metastases in esophageal carcinoma [TIGER study] : Study protocol of a multinational observational study

Author

Hagens, Eliza R.C., Van Berge Henegouwen, Mark I., Van Sandick, Johanna W., Cuesta, Miguel A., Van Der Peet, Donald L., Heisterkamp, Joos, Nieuwenhuijzen, Grard A.P., Rosman, Camiel, Scheepers, Joris J.G., Sosef, Meindert N., Van Hillegersberg, Richard, Lagarde, Sjoerd M., Nilsson, Magnus, Räsänen, Jari, Nafteux, Philippe, Pattyn, Piet, Hölscher, Arnulf H., Schröder, Wolfgang, Schneider, Paul M., Mariette, Christophe, Castoro, Carlo, Bonavina, Luigi, Rosati, Riccardo, De Manzoni, Giovanni, Mattioli, Sandro, Garcia, Josep Roig, Pera, Manuel, Griffin, Michael, Wilkerson, Paul, Chaudry, M. Asif, Sgromo, Bruno, Tucker, Olga, Cheong, Edward, Moorthy, Krishna, Walsh, Thomas N., Reynolds, John, Tachimori, Yuji, Inoue, Haruhiro, Matsubara, Hisahiro, Kosugi, Shin Ichi, Chen, Haiquan, Law, Simon Y.K., Pramesh, C. S., Puntambekar, Shailesh P., Murthy, Sudish, Linden, Philip, Hofstetter, Wayne L., Kuppusamy, Madhan K., Shen, K. Robert, Darling, Gail E., Sabino, Flávio D., Grimminger, Peter P., Meijer, Sybren L., Bergman, Jacques J.G.H.M., Hulshof, Maarten C.C.M., Van Laarhoven, Hanneke W.M., Mearadji, Banafsche, Bennink, Roel J., Annema, Jouke T., Dijkgraaf, Marcel G.W., Gisbertz, Suzanne S., Hagens, Eliza R.C., Van Berge Henegouwen, Mark I., Van Sandick, Johanna W., Cuesta, Miguel A., Van Der Peet, Donald L., Heisterkamp, Joos, Nieuwenhuijzen, Grard A.P., Rosman, Camiel, Scheepers, Joris J.G., Sosef, Meindert N., Van Hillegersberg, Richard, Lagarde, Sjoerd M., Nilsson, Magnus, Räsänen, Jari, Nafteux, Philippe, Pattyn, Piet, Hölscher, Arnulf H., Schröder, Wolfgang, Schneider, Paul M., Mariette, Christophe, Castoro, Carlo, Bonavina, Luigi, Rosati, Riccardo, De Manzoni, Giovanni, Mattioli, Sandro, Garcia, Josep Roig, Pera, Manuel, Griffin, Michael, Wilkerson, Paul, Chaudry, M. Asif, Sgromo, Bruno, Tucker, Olga, Cheong, Edward, Moorthy, Krishna, Walsh, Thomas N., Reynolds, John, Tachimori, Yuji, Inoue, Haruhiro, Matsubara, Hisahiro, Kosugi, Shin Ichi, Chen, Haiquan, Law, Simon Y.K., Pramesh, C. S., Puntambekar, Shailesh P., Murthy, Sudish, Linden, Philip, Hofstetter, Wayne L., Kuppusamy, Madhan K., Shen, K. Robert, Darling, Gail E., Sabino, Flávio D., Grimminger, Peter P., Meijer, Sybren L., Bergman, Jacques J.G.H.M., Hulshof, Maarten C.C.M., Van Laarhoven, Hanneke W.M., Mearadji, Banafsche, Bennink, Roel J., Annema, Jouke T., Dijkgraaf, Marcel G.W., and Gisbertz, Suzanne S.

Published
2019

46. Accuracy of 18F-FDG PET/CT in predicting residual disease after neoadjuvant chemoradiotherapy for esophageal cancer

Author

Valkema, Maria J., Noordman, Bo Jan, Wijnhoven, Bas P.L., Spaander, Manon C.W., Biermann, Katharina, Lagarde, Sjoerd M., Bennink, Roel J., Schreurs, Wendy M.J., Roef, Mark J., Hobbelink, Monique G.G., Janssen, Marcel J.R., Graven, Laura H., Van Lanschot, J. Jan B., Valkema, Roelf, Valkema, Maria J., Noordman, Bo Jan, Wijnhoven, Bas P.L., Spaander, Manon C.W., Biermann, Katharina, Lagarde, Sjoerd M., Bennink, Roel J., Schreurs, Wendy M.J., Roef, Mark J., Hobbelink, Monique G.G., Janssen, Marcel J.R., Graven, Laura H., Van Lanschot, J. Jan B., and Valkema, Roelf

Published
2019

47. Distribution of lymph node metastases in esophageal carcinoma [TIGER study]: Study protocol of a multinational observational study

Author

Divisie Beeld & Oncologie, Cancer, Hagens, Eliza R.C., Van Berge Henegouwen, Mark I., Van Sandick, Johanna W., Cuesta, Miguel A., Van Der Peet, Donald L., Heisterkamp, Joos, Nieuwenhuijzen, Grard A.P., Rosman, Camiel, Scheepers, Joris J.G., Sosef, Meindert N., Van Hillegersberg, Richard, Lagarde, Sjoerd M., Nilsson, Magnus, Räsänen, Jari, Nafteux, Philippe, Pattyn, Piet, Hölscher, Arnulf H., Schröder, Wolfgang, Schneider, Paul M., Mariette, Christophe, Castoro, Carlo, Bonavina, Luigi, Rosati, Riccardo, De Manzoni, Giovanni, Mattioli, Sandro, Garcia, Josep Roig, Pera, Manuel, Griffin, Michael, Wilkerson, Paul, Chaudry, M. Asif, Sgromo, Bruno, Tucker, Olga, Cheong, Edward, Moorthy, Krishna, Walsh, Thomas N., Reynolds, John, Tachimori, Yuji, Inoue, Haruhiro, Matsubara, Hisahiro, Kosugi, Shin Ichi, Chen, Haiquan, Law, Simon Y.K., Pramesh, C. S., Puntambekar, Shailesh P., Murthy, Sudish, Linden, Philip, Hofstetter, Wayne L., Kuppusamy, Madhan K., Shen, K. Robert, Darling, Gail E., Sabino, Flávio D., Grimminger, Peter P., Meijer, Sybren L., Bergman, Jacques J.G.H.M., Hulshof, Maarten C.C.M., Van Laarhoven, Hanneke W.M., Mearadji, Banafsche, Bennink, Roel J., Annema, Jouke T., Dijkgraaf, Marcel G.W., Gisbertz, Suzanne S., Divisie Beeld & Oncologie, Cancer, Hagens, Eliza R.C., Van Berge Henegouwen, Mark I., Van Sandick, Johanna W., Cuesta, Miguel A., Van Der Peet, Donald L., Heisterkamp, Joos, Nieuwenhuijzen, Grard A.P., Rosman, Camiel, Scheepers, Joris J.G., Sosef, Meindert N., Van Hillegersberg, Richard, Lagarde, Sjoerd M., Nilsson, Magnus, Räsänen, Jari, Nafteux, Philippe, Pattyn, Piet, Hölscher, Arnulf H., Schröder, Wolfgang, Schneider, Paul M., Mariette, Christophe, Castoro, Carlo, Bonavina, Luigi, Rosati, Riccardo, De Manzoni, Giovanni, Mattioli, Sandro, Garcia, Josep Roig, Pera, Manuel, Griffin, Michael, Wilkerson, Paul, Chaudry, M. Asif, Sgromo, Bruno, Tucker, Olga, Cheong, Edward, Moorthy, Krishna, Walsh, Thomas N., Reynolds, John, Tachimori, Yuji, Inoue, Haruhiro, Matsubara, Hisahiro, Kosugi, Shin Ichi, Chen, Haiquan, Law, Simon Y.K., Pramesh, C. S., Puntambekar, Shailesh P., Murthy, Sudish, Linden, Philip, Hofstetter, Wayne L., Kuppusamy, Madhan K., Shen, K. Robert, Darling, Gail E., Sabino, Flávio D., Grimminger, Peter P., Meijer, Sybren L., Bergman, Jacques J.G.H.M., Hulshof, Maarten C.C.M., Van Laarhoven, Hanneke W.M., Mearadji, Banafsche, Bennink, Roel J., Annema, Jouke T., Dijkgraaf, Marcel G.W., and Gisbertz, Suzanne S.

Published
2019

48. Accuracy of 18F-FDG PET/CT in predicting residual disease after neoadjuvant chemoradiotherapy for esophageal cancer

Author

Arts-assistenten Radiologie, Cancer, Arts-assistenten Nucleaire Geneesk., Valkema, Maria J., Noordman, Bo Jan, Wijnhoven, Bas P.L., Spaander, Manon C.W., Biermann, Katharina, Lagarde, Sjoerd M., Bennink, Roel J., Schreurs, Wendy M.J., Roef, Mark J., Hobbelink, Monique G.G., Janssen, Marcel J.R., Graven, Laura H., Van Lanschot, J. Jan B., Valkema, Roelf, Arts-assistenten Radiologie, Cancer, Arts-assistenten Nucleaire Geneesk., Valkema, Maria J., Noordman, Bo Jan, Wijnhoven, Bas P.L., Spaander, Manon C.W., Biermann, Katharina, Lagarde, Sjoerd M., Bennink, Roel J., Schreurs, Wendy M.J., Roef, Mark J., Hobbelink, Monique G.G., Janssen, Marcel J.R., Graven, Laura H., Van Lanschot, J. Jan B., and Valkema, Roelf

Published
2019

50. Active Surveillance Versus Immediate Surgery in Clinically Complete Responders After Neoadjuvant Chemoradiotherapy for Esophageal Cancer

Author

van der Wille, Berend J., primary, Noordman, Bo J., additional, Neijenhuis, Lisanne K. A., additional, Nieboer, Daan, additional, Nieuwenhuijzen, Grard A. P., additional, Sosef, Meindert N., additional, van Berge Henegouwen, Mark I., additional, Lagarde, Sjoerd M., additional, Spaander, Manon C. W., additional, Valkema, Roelf, additional, Biermann, Katharina, additional, Wijnhoven, Bas P. L., additional, van der Gaast, Ate, additional, van Lanschot, J. Jan B., additional, Doukas, Michael, additional, Nikkessen, Suzan, additional, Luyer, Misha, additional, Schoon, Erik J., additional, Roef, Mark J., additional, van Lijnschoten, Ineke, additional, Oostenbrug, Liekele E., additional, Riedl, Robert G., additional, Gisbertz, Suzanne S., additional, Krishnadath, Kausilia K., additional, Bennink, Roel J., additional, and Meijer, Sybren L., additional

Published
2019
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