1,283 results on '"Borén, Jan"'
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2. Regulation of meiotic telomere dynamics through membrane fluidity promoted by AdipoR2-ELOVL2
3. Contribution of intestinal triglyceride-rich lipoproteins to residual atherosclerotic cardiovascular disease risk in individuals with type 2 diabetes on statin therapy
4. Extracellular vesicles transport RNA between cells: Unraveling their dual role in diagnostics and therapeutics
5. Synthesis, spectroscopic characterization, DFT and molecular docking of N-(3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl) naphthalene-1-sulfonamide derivatives
6. Design and synthesis of novel JNK inhibitors targeting liver pyruvate kinase for the treatment of non-alcoholic fatty liver disease and hepatocellular carcinoma
7. Adipocyte PI3K links adipostasis with baseline insulin secretion at fasting through an adipoincretin effect
8. Cardiac arrhythmias and conduction abnormalities in patients with type 2 diabetes
9. Combined metabolic activators improve cognitive functions in Alzheimer’s disease patients: a randomised, double-blinded, placebo-controlled phase-II trial
10. Sulfone-based human liver pyruvate kinase inhibitors – Design, synthesis and in vitro bioactivity
11. Non-coronary peripheral arterial complications in people with type 2 diabetes: a Swedish retrospective cohort study
12. Non-coronary arterial outcomes in people with type 1 diabetes mellitus: a Swedish retrospective cohort study
13. Intussusceptive Angiogenesis in Human Metastatic Malignant Melanoma
14. Lipoprotein(a) Is Markedly More Atherogenic Than LDL: An Apolipoprotein B-Based Genetic Analysis
15. High levels of lipoprotein(a) in transgenic mice exacerbate atherosclerosis and promote vulnerable plaque features in a sex-specific manner
16. The acute effect of different NAD+ precursors included in the combined metabolic activators
17. Longitudinal metabolomics analysis reveals the acute effect of cysteine and NAC included in the combined metabolic activators
18. AdipoR2 recruits protein interactors to promote fatty acid elongation and membrane fluidity
19. Cerebrospinal fluid sulfatide isoforms lack diagnostic utility in separating progressive from relapsing-remitting multiple sclerosis
20. Tuning liver pyruvate kinase activity up or down with a new class of allosteric modulators
21. Metabolism of triglyceride-rich lipoproteins in health and dyslipidaemia
22. Metabolism of Triglyceride-Rich Lipoproteins
23. Cardiomyocytes, sphingolipids and cardio myotoxicity
24. The link between diabetes and cardiovascular disease
25. Discovery of therapeutic agents targeting PKLR for NAFLD using drug repositioning
26. Twenty Years of Cardiovascular Complications and Risk Factors in Patients With Type 2 Diabetes: A Nationwide Swedish Cohort Study
27. Modified lipid metabolism and cytosolic phospholipase A2 activation in mesangial cells under pro-inflammatory conditions
28. Sphingosine 1-phosphate mediates adiponectin receptor signaling essential for lipid homeostasis and embryogenesis
29. Anthraquinone derivatives as ADP-competitive inhibitors of liver pyruvate kinase
30. Biosynthesis and Metabolism of ApoB-Containing Lipoproteins.
31. The role of circulating galectin-1 in type 2 diabetes and chronic kidney disease: evidence from cross-sectional, longitudinal and Mendelian randomisation analyses
32. A network-based approach reveals the dysregulated transcriptional regulation in non-alcoholic fatty liver disease
33. Role of Perilipins in Oxidative Stress—Implications for Cardiovascular Disease
34. Cholesterol efflux promoting function of high-density lipoproteins in calcific aortic valve stenosis
35. APRIL limits atherosclerosis by binding to heparan sulfate proteoglycans
36. Stratification of patients with clear cell renal cell carcinoma to facilitate drug repositioning
37. Family-specific aggregation of lipid GWAS variants confers the susceptibility to familial hypercholesterolemia in a large Austrian family
38. Low-density lipoproteins cause atherosclerotic cardiovascular disease. 1. Evidence from genetic, epidemiologic, and clinical studies. A consensus statement from the European Atherosclerosis Society Consensus Panel
39. Aging AdipoR2‐deficient mice are hyperactive with enlarged brains excessively rich in saturated fatty acids.
40. Current Status of COVID-19 Therapies and Drug Repositioning Applications
41. A systems biology approach for studying neurodegenerative diseases
42. Classification of clear cell renal cell carcinoma based on PKM alternative splicing
43. Quantifying atherogenic lipoproteins for lipid-lowering strategies: Consensus-based recommendations from EAS and EFLM
44. Rare dyslipidaemias, from phenotype to genotype to management: a European Atherosclerosis Society task force consensus statement
45. Impact of proprotein convertase subtilisin/kexin type 9 inhibition with evolocumab on the postprandial responses of triglyceride-rich lipoproteins in type II diabetic subjects
46. CD38 as a therapeutic target in pediatric Burkitt’s Lymphoma: insights from a comparative approach (Running title: Targeting CD38 in pediatric Burkitt's Lymphoma)
47. Liver receptor homolog‐1 is a critical determinant of methyl‐pool metabolism
48. Metabolic network-based stratification of hepatocellular carcinoma reveals three distinct tumor subtypes
49. Palmitic acid causes increased dihydroceramide levels when desaturase expression is directly silenced or indirectly lowered by silencing AdipoR2
50. Antibodies against apoB100 peptide 210 inhibit atherosclerosis in apoE-/- mice
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