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187 results on '"Carver, Peggy L"'

8. Risk Factors for Nontuberculous Mycobacteria Infections in Solid Organ Transplant Recipients: A Multinational Case-Control Study

Author

Mejia-Chew, Carlos, primary, Carver, Peggy L, additional, Rutjanawech, Sasinuch, additional, Camargo, Luis F Aranha, additional, Fernandes, Ruan, additional, Belga, Sara, additional, Daniels, Shay Anne, additional, Müller, Nicolas J, additional, Burkhard, Sara, additional, Theodoropoulos, Nicole M, additional, Postma, Douwe F, additional, van Duijn, Pleun J, additional, Fariñas, María Carmen, additional, González-Rico, Claudia, additional, Hand, Jonathan, additional, Lowe, Adam, additional, Bodro, Marta, additional, Vanino, Elisa, additional, Cruz, Ana Fernández, additional, Ramos, Antonio, additional, Makek, Mateja Jankovic, additional, Mjahed, Ribal Bou, additional, Manuel, Oriol, additional, Kamar, Nassim, additional, Calvo-Cano, Antonia, additional, Carrasco, Laura Rueda, additional, Muñoz, Patricia, additional, Rodríguez, Sara, additional, Pérez-Recio, Sandra, additional, Sabé, Núria, additional, Álvarez, Regino Rodríguez, additional, Silva, José Tiago, additional, Mularoni, Alessandra, additional, Vidal, Elisa, additional, Alonso-Titos, Juana, additional, del Rosal, Teresa, additional, Classen, Annika Y, additional, Goss, Charles W, additional, Agarwal, Mansi, additional, and López-Medrano, Francisco, additional

Published
2022
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10. Use of Computer-Assisted Instruction to Review Microbiology and Antimicrobial Agents.

Author

Carver, Peggy L.

Abstract

A study assessed the effectiveness of a microcomputer-assisted instructional program using graphics, color, and text in simulations to enhance pharmacy students' knowledge of microbiology and antimicrobial agents. Results indicated high short- and long-term retention of information presented and higher levels of knowledge and comprehension among these students (n=111) than others. (Author/MSE)

Published
1991

12. Candida glabrata fungemia: experience in a tertiary care center

Author

Malani, Anurag, Hmoud, Jareer, Chiu, Loretta, Carver, Peggy L., Bielaczyc, Andrew, and Kauffman, Carol A.

Subjects
Itraconazole -- Dosage and administration, Fluconazole -- Dosage and administration, Candidiasis -- Risk factors, Candidiasis -- Development and progression, Candidiasis -- Drug therapy, Health, Health care industry
Published
2005

27. From macrolides to ketolides: what is available for the treatment of outpatient respiratory tract infections?

Author

Carver, Peggy L.

Subjects
Erythromycin -- Dosage and administration, Erythromycin -- Genetic aspects, Ribosomal RNA -- Genetic aspects, Ethinyl estradiol -- Dosage and administration, Ethinyl estradiol -- Genetic aspects, Pharmaceutical industry -- Genetic aspects, Military-industrial complex -- Genetic aspects, Carbamates -- Genetic aspects, Isoenzymes -- Genetic aspects, Professional soccer -- Genetic aspects, Bacterial pneumonia -- Drug therapy, Bacterial pneumonia -- Genetic aspects, Pneumonia -- Drug therapy, Pneumonia -- Genetic aspects, Cytochrome P-450 -- Genetic aspects, Pediatrics -- Genetic aspects, Methylation -- Genetic aspects, Medical research -- Genetic aspects, Medicine, Experimental -- Genetic aspects, Chemotherapy -- Genetic aspects, Drug resistance in microorganisms -- Drug therapy, Drug resistance in microorganisms -- Genetic aspects, Antacids -- Dosage and administration, Antacids -- Genetic aspects, Cancer -- Chemotherapy, Cancer -- Genetic aspects, Health
Published
2002

29. Long-term risk of hepatocellular carcinoma mortality in 23220 hospitalized patients treated with micafungin or other parenteral antifungals

Author

Schneeweiss, Sebastian, primary, Carver, Peggy L, additional, Datta, Kausik, additional, Galar, Alicia, additional, Johnson, Melissa D, additional, Letourneau, Alyssa R, additional, Marty, Francisco M, additional, Nagel, Jerod, additional, Najdzinowicz, Maryann, additional, Saul, Melissa, additional, Schuster, Mindy, additional, Shoham, Shmuel, additional, Silveira, Fernanda P, additional, Varughese, Christy, additional, Wilck, Marissa, additional, Weatherby, Lisa, additional, Oene, Joop van, additional, and Walker, Alexander M, additional

Published
2019
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33. Long-term risk of hepatocellular carcinoma mortality in 23220 hospitalized patients treated with micafungin or other parenteral antifungals.

Author

Schneeweiss, Sebastian, Carver, Peggy L, Datta, Kausik, Galar, Alicia, Johnson, Melissa D, Letourneau, Alyssa R, Marty, Francisco M, Nagel, Jerod, Najdzinowicz, Maryann, Saul, Melissa, Schuster, Mindy, Shoham, Shmuel, Silveira, Fernanda P, Varughese, Christy, Wilck, Marissa, Weatherby, Lisa, Oene, Joop van, and Walker, Alexander M

Subjects
*HOSPITAL patients, *HEPATOCELLULAR carcinoma, *ELECTRONIC health records, *CARCINOGENICITY, *MORTALITY, *ANTIFUNGAL agents, *RESEARCH, *LIVER tumors, *TIME, *RESEARCH methodology, *RETROSPECTIVE studies, *MEDICAL cooperation, *EVALUATION research, *PARENTERAL infusions, *COMPARATIVE studies, *HOSPITAL care, *FUNGEMIA, *PROBABILITY theory
Abstract

Background: Liver tumours observed in rats exposed to micafungin led to a black box warning upon approval in Europe in 2008. Micafungin's risk for liver carcinogenicity in humans has not been investigated. We sought to describe the risk of fatal hepatocellular carcinoma (HCC) among persons who received micafungin and other parenteral antifungals (PAFs) with up to 12 years of follow-up.Methods: We assembled a US multicentre cohort of hospitalized patients who received micafungin or other PAFs between 2005 and 2012. We used propensity score (PS) matching on patient characteristics from electronic medical records to compare rates of HCC mortality identified through the National Death Index though to the end of December 2016. We computed HRs and 95% CIs.Results: A total of 40110 patients who received a PAF were identified; 6903 micafungin recipients (87% of those identified) were successfully matched to 16317 comparator PAF users. Ten incident HCC deaths, one in the micafungin-exposed group and nine among comparator PAF users, occurred in 71285 person-years of follow-up. The HCC mortality rate was 0.05 per 1000 person-years in micafungin patients and 0.17 per 1000 person-years in comparator PAF patients. The PS-matched HR for micafungin versus comparator PAF was 0.29 (95% CI 0.04-2.24).Conclusions: Both micafungin and comparator PAFs were associated with HCC mortality rates of <0.2 per 1000 person-years. Given the very low event rates, any potential risk for HCC should not play a role in clinical decisions regarding treatment with micafungin or other PAFs investigated in this study. [ABSTRACT FROM AUTHOR]

Published
2020
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36. Dosing and Monitoring of Trace Elements in Long-Term Home Parenteral Nutrition Patients

Author

Btaiche, Imad F., Carver, Peggy L., Welch, Katheen B., Btaiche, Imad F., Carver, Peggy L., and Welch, Katheen B.

Abstract

Background: Trace elements (TEs) dosing and monitoring in home parenteral nutrition (PN) patients vary with their underlying conditions. Methods: This retrospective observational study evaluated parenteral TE dosing, serum TE concentrations and monitoring, and dose-concentration relationships between TE doses and serum TE concentrations in 26 adult and adolescent home PN patients. Results: There was a total of 40,493 PN days. Average parenteral zinc doses of 9.1 mg/d and 7.6 mg/d resulted in the majority of serum zinc concentrations (90%) within normal range in patients with and without short bowel syndrome (SBS), respectively. Selenium at about 70 mcg/d resulted in about 60% of serum selenium concentrations within normal range, with 38% of values below normal in patients with and without SBS alike. Copper at 1 mg/d resulted in 22.5% of serum copper concentrations above the normal range. The majority of serum manganese (94.6%) and chromium (96%) concentrations were elevated. Serum TE concentrations were infrequently monitored. Significant relationships existed between doses and serum concentrations for zinc (P < .0001), manganese (P = .012), and chromium (P < .0001) but not for selenium or copper. Conclusions: TE doses in home PN should be individualized and adjusted based on regular monitoring of TE status. In long-term home PN patients, higher zinc and selenium doses may be necessary to maintain their normal serum concentrations. Lower copper doses and restrictions of manganese and chromium supplementation may be needed to avoid their accumulation. Relationships between TE doses and serum TE concentrations vary for each TE and underlying clinical conditions.

Published
2016

38. Short-term risk of liver and renal injury in hospitalized patients using micafungin: a multicentre cohort study

Author

Schneeweiss, Sebastian, primary, Carver, Peggy L., additional, Datta, Kausik, additional, Galar, Alicia, additional, Johnson, Melissa D., additional, Johnson, Matthew G., additional, Marty, Francisco M., additional, Nagel, Jerod, additional, Najdzinowicz, Maryann, additional, Saul, Melissa, additional, Shoham, Shmuel, additional, Silveira, Fernanda P., additional, Varughese, Christy A., additional, Wilck, Marissa, additional, Weatherby, Lisa, additional, Auton, Tim, additional, and Walker, Alexander M., additional

Published
2016
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40. Real-World Experience with Echinocandin MICs against Candida Species in a Multicenter Study of Hospitals That Routinely Perform Susceptibility Testing of Bloodstream Isolates

Author

Eschenauer, Gregory A., primary, Nguyen, M. Hong, additional, Shoham, Shmuel, additional, Vazquez, Jose A., additional, Morris, Arthur J., additional, Pasculle, William A., additional, Kubin, Christine J., additional, Klinker, Kenneth P., additional, Carver, Peggy L., additional, Hanson, Kimberly E., additional, Chen, Sharon, additional, Lam, Simon W., additional, Potoski, Brian A., additional, Clarke, Lloyd G., additional, Shields, Ryan K., additional, and Clancy, Cornelius J., additional

Published
2014
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