169 results on '"Mumm, Jeff S."'
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2. NTR 2.0: a rationally engineered prodrug-converting enzyme with substantially enhanced efficacy for targeted cell ablation
3. Selective Cell Ablation Using an Improved Prodrug-Converting Nitroreductase
4. A metagenomic library cloning strategy that promotes high-level expression of captured genes to enable efficient functional screening
5. Intrinsic epigenetic control of angiogenesis in induced pluripotent stem cell-derived endothelium regulates vascular regeneration
6. Three-dimensional automated reporter quantification (3D-ARQ) technology enables quantitative screening in retinal organoids
7. Structural Evaluation of a Nitroreductase Engineered for Improved Activation of the 5-Nitroimidazole PET Probe SN33623.
8. Molecular regulation of retinal regeneration is context specific
9. Transcriptomic comparison of two selective retinal cell ablation paradigms in zebrafish reveals shared and cell-specific regenerative responses
10. A new model of inducible chronic hyperglycemia
11. ACVR1C/SMAD2 signaling promotes invasion and growth in retinoblastoma
12. Silencer-delimited transgenesis: NRSE/RE1 sequences promote neural-specific transgene expression in a NRSF/REST-dependent manner
13. Immunomodulation-accelerated neuronal regeneration following selective rod photoreceptor cell ablation in the zebrafish retina
14. The Crystal Structure of Engineered Nitroreductase NTR 2.0 and Impact of F70A and F108Y Substitutions on Substrate Specificity
15. A metagenomic library cloning strategy that promotes high-level expression of captured genes to enable efficient functional screening
16. Thalamic neurons drive distinct forms of motor asymmetry that are conserved in teleost and dependent on visual evolution
17. The Crystal Structure of Engineered Nitroreductase NTR 2.0 and Impact of F70A and F108Y Mutations on Substrate Specificity
18. Downregulation of Nodal inhibits metastatic progression in retinoblastoma
19. Mesoscopic oblique plane microscopy with a diffractive light-sheet for large-scale 4D cellular resolution imaging
20. ARQiv-HTS, a versatile whole-organism screening platform enabling in vivo drug discovery at high-throughput rates
21. Notch Inhibition Promotes Regeneration and Immunosuppression Supports Cone Survival in a Zebrafish Model of Inherited Retinal Dystrophy
22. A New Transgenic Line for Rapid and Complete Neutrophil Ablation
23. COP1 and GSK3β Cooperate to Promote c-Jun Degradation and Inhibit Breast Cancer Cell Tumorigenesis
24. Mesoscopic oblique plane microscopy (Meso-OPM) with a diffractive light sheet- enabling large-scale 4D cellular resolution imaging
25. Notch inhibition promotes regeneration and immunosuppression supports cone survival in a zebrafish model of inherited retinal dystrophy
26. Generation, Differentiation, and Maturation of Olfactory Receptor Neurons In Vitro
27. Gfap-positive radial glial cells are an essential progenitor population for later-born neurons and glia in the zebrafish spinal cord
28. Large-scale phenotypic drug screen identifies neuroprotectants in zebrafish and mouse models of retinitis pigmentosa
29. Engineering the Escherichia coli Nitroreductase NfsA to Create a Flexible Enzyme-Prodrug Activation System
30. Author response: Large-scale phenotypic drug screen identifies neuroprotectants in zebrafish and mouse models of retinitis pigmentosa
31. Advances in zebrafish chemical screening technologies
32. Dendrimer-targeted immunosuppression of microglia reactivity super-accelerates photoreceptor regeneration kinetics in the zebrafish retina
33. Transcriptomic comparison of two selective retinal cell ablation paradigms in zebrafish reveals shared and cell-specific regenerative responses
34. NTR 2.0: a rationally-engineered prodrug converting enzyme with substantially enhanced efficacy for targeted cell ablation
35. Large-scale Phenotypic Drug Screen Identifies Neuroprotectants in Zebrafish and Mouse Models of Retinitis Pigmentosa
36. Knockdown of zebrafish Lgi1a results in abnormal development, brain defects and a seizure-like behavioral phenotype
37. Decision letter: Identification of drug modifiers for RYR1-related myopathy using a multi-species discovery pipeline
38. Decision letter: Chemoptogenetic ablation of neuronal mitochondria in vivo with spatiotemporal precision and controllable severity
39. Laminar circuit formation in the vertebrate retina
40. Let's get small (and smaller): Combining zebrafish and nanomedicine to advance neuroregenerative therapeutics
41. ACVR1C/SMAD2 signaling promotes invasion and growth in retinoblastoma
42. Multiplexed CRISPR/Cas9 Targeting of Genes Implicated in Retinal Regeneration and Degeneration
43. Enabling quantitative screening in retinal organoids: 3D automated reporter quantification technology (3D-ARQ)
44. Chemical genetics and regeneration
45. An inducible model of chronic hyperglycemia
46. First quantitative high-throughput screen in zebrafish identifies novel pathways for increasing pancreatic β-cell mass
47. Author response: First quantitative high-throughput screen in zebrafish identifies novel pathways for increasing pancreatic β-cell mass
48. Enhanced Cell-Specific Ablation in Zebrafish Using a Triple Mutant of Escherichia Coli Nitroreductase
49. Evaluating human cancer cell metastasis in zebrafish
50. The nitroreductase system of inducible targeted ablation facilitates cell-specific regenerative studies in zebrafish
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