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5. Call for Emergency Action to Limit Global Temperature Increases, Restore Biodiversity, and Protect Health: Wealthy nations must do much more, much faster

Author

Atwoli, Lukoye, Baqui, Abdullah H., Benfield, Thomas, Bosurgi, Raffaella, Godlee, Fiona, Hancocks, Stephen, Horton, Richard, Laybourn-Langton, Laurie, Monteiro, Carlos Augusto, Norman, Ian, Patrick, Kirsten, Praities, Nigel, Olde Rikkert, Marcel G.M., Rubin, Eric J., Sahni, Peush, Smith, Richard, Talley, Nick, Turale, Sue, and Vázquez, Damián

Published
2021
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8. Cognitive Outcomes of Long-term Benzodiazepine and Related Drug (BDZR) Use in People Living With Mild to Moderate Alzheimer's Disease: Results From NILVAD

Author

Lawlor, Brian, Segurado, Ricardo, Kennelly, Sean, Olde Rikkert, Marcel G.M., Howard, Robert, Pasquier, Florence, Börjesson-Hanson, Anne, Tsolaki, Magda, Lucca, Ugo, Molloy, D. William, Coen, Robert, Riepe, Matthias W., Kálmán, János, Kenny, Rose Anne, Cregg, Fiona, O'Dwyer, Sarah, Walsh, Cathal, Adams, Jessica, Banzi, Rita, Breuilh, Laetitia, Daly, Leslie, Hendrix, Suzanne, Aisen, Paul, Gaynor, Siobhan, Sheikhi, Ali, Taekema, Diana G., Verhey, Frans R., Nemni, Raffaello, Nobili, Flavio, Franceschi, Massimo, Frisoni, Giovanni, Zanetti, Orazio, Konsta, Anastasia, Anastasios, Orologas, Nenopoulou, Styliani, Tsolaki-Tagaraki, Fani, Pakaski, Magdolna, Dereeper, Olivier, Sayette, Vincent de la, Sénéchal, Olivier, Lavenu, Isabelle, Devendeville, Agnès, Calais, Gauthier, Crawford, Fiona, Mullan, Michael, Aalten, Pauline, Berglund, Maria A., Claassen, Jurgen A., De Heus, Rianne A., De Jong, Daan L.K., Godefroy, Olivier, Hutchinson, Siobhan, Ioannou, Aikaterini, Jonsson, Michael, Kent, Annette, Kern, Jürgen, Nemtsas, Petros, Panidou, Minoa-Kalliopi, Abdullah, Laila, Paris, Daniel, Santoso, Angelina M., van Spijker, Gerrita J., Spiliotou, Martha, Thomoglou, Georgia, Wallin, Anders, Dyer, Adam H., Murphy, Claire, and Kennelly, Sean P.

Published
2020
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10. Reducing the Risks of Nuclear War—The Role of Health Professionals

Author

Abbasi, Kamran, primary, Ali, Parveen, additional, Barbour, Virginia, additional, Bibbins-Domingo, Kirsten, additional, Olde Rikkert, Marcel G.M., additional, Haines, Andy, additional, Helfand, Ira, additional, Horton, Richard, additional, Mash, Bob, additional, Mitra, Arun, additional, Monteiro, Carlos, additional, Naumova, Elena N., additional, Rubin, Eric J., additional, Ruff, Tilman, additional, Sahni, Peush, additional, Tumwine, James, additional, Yonga, Paul, additional, and Zielinski, Chris, additional

Published
2023
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14. Reducing the risks of nuclear war – The role of health professionals

Author

Kamran, Abbasi, primary, Ali, Parveen, additional, Barbour, Virginia, additional, Bibbins-Domingo, Kirsten, additional, Olde Rikkert, Marcel G.M, additional, Horton, Richard, additional, Mash, Robert, additional, Monteiro, Carlos, additional, Naumova, Elena N., additional, Rubin, Eric J, additional, Sahni, Peush, additional, Tumwine, James, additional, Yonga, Paul, additional, Zielinski, Chris, additional, Mitra, Arun, additional, Ruff, Tilman, additional, Haines, Andy, additional, and Helfand, Ira, additional

Published
2023
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18. Call for Emergency Action to Limit Global Temperature Increases, Restore Biodiversity, and Protect Health

Author

Atwoli, Lukoye, Baqui, Abdullah H., Benfield, Thomas, Bosurgi, Raffaella, Godlee, Fiona, Hancocks, Stephen, Horton, Richard, Laybourn-Langton, Laurie, Monteiro, Carlos Augusto, Norman, Ian, Patrick, Kirsten, Praities, Nigel, Olde Rikkert, Marcel G.M., Rubin, Eric J., Sahni, Peush, Smith, Richard, Talley, Nick, Turale, Sue, and Vazquez, Damian

Subjects
Environmental health -- International aspects, Biological diversity conservation -- International aspects, Global temperature changes -- Health aspects, Public health -- International aspects
Abstract

Wealthy nations must do much more, much faster ([dagger]) The UN General Assembly in September 2021 will bring countries together at a critical time for marshalling collective action to tackle [...]

Published
2021
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23. Older Adults’ Views on Social Interactions and Online Socializing Games–A Qualitative Study

Author

Leerstoel Buskens, Social Networks, Solidarity and Inequality, Janssen, Jeroen, Kremers, Evi M., Nieuwboer, Minke S., Châtel, Bas D.L., Corten, Rense, Olde Rikkert, Marcel G.M., Peeters, G. M.E.E., Leerstoel Buskens, Social Networks, Solidarity and Inequality, Janssen, Jeroen, Kremers, Evi M., Nieuwboer, Minke S., Châtel, Bas D.L., Corten, Rense, Olde Rikkert, Marcel G.M., and Peeters, G. M.E.E.

Published
2023

24. Call for emergency action to limit global temperature increases, restore biodiversity, and protect health:Wealthy nations must do much more, much faster

Author

Atwoli, Lukoye, Baqui, Abdullah H., Benfield, Thomas, Bosurgi, Raffaella, Godlee, Fiona, Hancocks, Stephen, Horton, Richard, Laybourn-Langton, Laurie, Monteiro, Carlos Augusto, Norman, Ian, Patrick, Kirsten, Praities, Nigel, Olde Rikkert, Marcel G.M., Rubin, Eric J., Sahni, Peush, Smith, Richard, Talley, Nick, Turale, Sue, Vázquez, Damián, Atwoli, Lukoye, Baqui, Abdullah H., Benfield, Thomas, Bosurgi, Raffaella, Godlee, Fiona, Hancocks, Stephen, Horton, Richard, Laybourn-Langton, Laurie, Monteiro, Carlos Augusto, Norman, Ian, Patrick, Kirsten, Praities, Nigel, Olde Rikkert, Marcel G.M., Rubin, Eric J., Sahni, Peush, Smith, Richard, Talley, Nick, Turale, Sue, and Vázquez, Damián

Published
2023

32. Older Adults’ Views on Social Interactions and Online Socializing Games–A Qualitative Study

Author

Janssen, Jeroen, Kremers, Evi M., Nieuwboer, Minke S., Châtel, Bas D.L., Corten, Rense, Olde Rikkert, Marcel G.M., Peeters, G. M.E.E., Leerstoel Buskens, and Social Networks, Solidarity and Inequality

Subjects
Nursing (miscellaneous), social isolation, loneliness, co-design, digital technology, qualitative research, Social Sciences (miscellaneous), Social contact
Abstract

Age-related difficulties and quarantine restrictions impede the possibilities to maintain contact with one’s social network. Maintaining these contacts may be supported by digital games. To develop effective and feasible digital tools to foster social interaction, we aimed to explore what older adults find important in social contact and what barriers and enablers they foresee in digital gaming interventions as network support aids. Two focus groups and 20 semi-structured interviews (N = 29) with older adults (aged 55–87) were held to explore the research questions. Furthermore, a questionnaire was administered (N = 29) containing measures of loneliness, frailty, and social network size. Participants found ‘reciprocity’, ‘in-person contact’, and ‘personal connection’ important in contact with strong ties. Online games were not used much for socializing but may be used in the future, particularly by less mobile older adults. Future social gaming interventions should be challenging, user-friendly, and offer the possibility to communicate. Digital co-designed interventions that are feasible, challenging, intuitive, and trigger meaningful communication may strengthen social interactions in older adults. They may be a relevant social support tool in periods of interaction limitations due to functional impairment or social isolation.

Published
2023

35. Physical Exercise Training Improves Quality of Life in Healthy Older Adults: A Meta-Analysis.

Author

Raafs, Bente M., Karssemeijer, Esther G.A., Van der Horst, Lizzy, Aaronson, Justine A., Olde Rikkert, Marcel G.M., and Kessels, Roy P.C.

Subjects
EXERCISE & psychology, AGING, CONFIDENCE intervals, HEALTH promotion, META-analysis, QUALITY of life, SYSTEMATIC reviews, SECONDARY analysis, INDEPENDENT living, OLD age
Abstract

The current meta-analysis first aimed to quantify the overall effect of physical exercise training on the quality of life (QoL) in healthy older adults. Second, the effects on the social, physical, and psychological QoL were assessed. In total, 16 randomized controlled trials were included. The primary analysis showed a medium effect of physical exercise training on QoL in healthy older adults (standard mean difference [SMD] = 0.38, confidence interval, CI, [0.18, 0.59], p <.05). The secondary analyses showed a positive medium effect of physical exercise training on the physical component of QoL (SMD = 0.39, CI [0.17, 0.60], p <.05), and a positive medium effect of physical exercise training on the psychological component of QoL (SMD = 0.348, CI [0.125, 0.570], p <.05), and no significant effect of physical exercise training on the social component of QoL was observed (SMD = 0.16, CI [−0.07, 0.38], p =.17). These findings warrant implementation efforts pertaining to exercise training for older adults to improve the QoL in our aging societies. [ABSTRACT FROM AUTHOR]

Published
2020
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40. Call for emergency action to limit global temperature increases, restore biodiversity, and protect health

Author

Atwoli, Lukoye, Baqui, Abdullah H., Benfield, Thomas, Bosurgi, Raffaella, Godlee, Fiona, Hancocks, Stephen, Horton, Richard, Laybourn-Langton, Laurie, Monteiro, Carlos Augusto, Norman, Ian, Patrick, Kirsten, Praities, Nigel, Olde Rikkert, Marcel G.M., Rubin, Eric J., Sahni, Peush, Smith, Richard, Talley, Nick, Turale, Sue, Vázquez, Damián, Atwoli, Lukoye, Baqui, Abdullah H., Benfield, Thomas, Bosurgi, Raffaella, Godlee, Fiona, Hancocks, Stephen, Horton, Richard, Laybourn-Langton, Laurie, Monteiro, Carlos Augusto, Norman, Ian, Patrick, Kirsten, Praities, Nigel, Olde Rikkert, Marcel G.M., Rubin, Eric J., Sahni, Peush, Smith, Richard, Talley, Nick, Turale, Sue, and Vázquez, Damián

Published
2022

41. Prevalence Estimates of Amyloid Abnormality Across the Alzheimer Disease Clinical Spectrum

Author

Jansen, Willemijn J., Janssen, Olin, Tijms, Betty M., Vos, Stephanie J.B., Ossenkoppele, Rik, Visser, Pieter Jelle, Aarsland, Dag, Alcolea, Daniel, Altomare, Daniele, Von Arnim, Christine, Baiardi, Simone, Baldeiras, Ines, Barthel, Henryk, Bateman, Randall J., Van Berckel, Bart, Binette, Alexa Pichet, Blennow, Kaj, Boada, Merce, Boecker, Henning, Bottlaender, Michel, Den Braber, Anouk, Brooks, David J., Van Buchem, Mark A., Camus, Vincent, Carill, Jose Manuel, Cerman, Jiri, Chen, Kewei, Chételat, Gaël, Chipi, Elena, Cohen, Ann D., Daniels, Alisha, Delarue, Marion, Didic, Mira, Drzezga, Alexander, Dubois, Bruno, Eckerström, Marie, Ekblad, Laura L., Engelborghs, Sebastiaan, Epelbaum, Stéphane, Fagan, Anne M., Fan, Yong, Fladby, Tormod, Fleisher, Adam S., Van Der Flier, Wiesje M., Förster, Stefan, Fortea, Juan, Frederiksen, Kristian Steen, Freund-Levi, Yvonne, Frings, Lars, Frisoni, Giovanni B., Fröhlich, Lutz, Gabryelewicz, Tomasz, Gertz, Hermann Josef, Gill, Kiran Dip, Gkatzima, Olymbia, Gómez-Tortosa, Estrella, Grimmer, Timo, Guedj, Eric, Habeck, Christian G., Hampel, Harald, Handels, Ron, Hansson, Oskar, Hausner, Lucrezia, Hellwig, Sabine, Heneka, Michael T., Herukka, Sanna Kaisa, Hildebrandt, Helmut, Hodges, John, Hort, Jakub, Huang, Chin Chang, Iriondo, Ane Juaristi, Itoh, Yoshiaki, Ivanoiu, Adrian, Jagust, William J., Jessen, Frank, Johannsen, Peter, Johnson, Keith A., Kandimalla, Ramesh, Kapaki, Elisabeth N., Kern, Silke, Kilander, Lena, Klimkowicz-Mrowiec, Aleksandra, Klunk, William E., Koglin, Norman, Kornhuber, Johannes, Kramberger, Milica G., Kuo, Hung Chou, Van Laere, Koen, Landau, Susan M., Landeau, Brigitte, Lee, Dong Young, De Leon, Mony, Leyton, Cristian E., Lin, Kun Ju, Lleó, Alberto, Löwenmark, Malin, Madsen, Karine, Maier, Wolfgang, Marcusson, Jan, Marquié, Marta, Martinez-Lage, Pablo, Maserejian, Nancy, Mattsson, Niklas, De Mendonça, Alexandre, Meyer, Philipp T., Miller, Bruce L., Minatani, Shinobu, Mintun, Mark A., Mok, Vincent C.T., Molinuevo, Jose Luis, Morbelli, Silvia Daniela, Morris, John C., Mroczko, Barbara, Na, Duk L., Newberg, Andrew, Nobili, Flavio, Nordberg, Agneta, Olde Rikkert, Marcel G.M., De Oliveira, Catarina Resende, Olivieri, Pauline, Orellana, Adela, Paraskevas, George, Parchi, Piero, Pardini, Matteo, Parnetti, Lucilla, Peters, Oliver, Poirier, Judes, Popp, Julius, Prabhakar, Sudesh, Rabinovici, Gil D., Ramakers, Inez H., Rami, Lorena, Reiman, Eric M., Rinne, Juha O., Rodrigue, Karen M., Rodríguez-Rodriguez, Eloy, Roe, Catherine M., Rosa-Neto, Pedro, Rosen, Howard J., Rot, Uros, Rowe, Christopher C., Rüther, Eckart, Ruiz, Agustín, Sabri, Osama, Sakhardande, Jayant, Sánchez-Juan, Pascual, Sando, Sigrid Botne, Santana, Isabel, Sarazin, Marie, Scheltens, Philip, Schröder, Johannes, Selnes, Per, Seo, Sang Won, Silva, Dina, Skoog, Ingmar, Snyder, Peter J., Soininen, Hilkka, Sollberger, Marc, Sperling, Reisa A., Spiru, Luisa, Stern, Yaakov, Stomrud, Erik, Takeda, Akitoshi, Teichmann, Marc, Teunissen, Charlotte E., Thompson, Louisa I., Tomassen, Jori, Tsolaki, Magda, Vandenberghe, Rik, Verbeek, Marcel M., Verhey, Frans R.J., Villemagne, Victor, Villeneuve, Sylvia, Vogelgsang, Jonathan, Waldemar, Gunhild, Wallin, Anders, Wallin, Åsa K., Wiltfang, Jens, Wolk, David A., Yen, Tzu Chen, Zboch, Marzena, Zetterberg, Henrik, Jansen, Willemijn J., Janssen, Olin, Tijms, Betty M., Vos, Stephanie J.B., Ossenkoppele, Rik, Visser, Pieter Jelle, Aarsland, Dag, Alcolea, Daniel, Altomare, Daniele, Von Arnim, Christine, Baiardi, Simone, Baldeiras, Ines, Barthel, Henryk, Bateman, Randall J., Van Berckel, Bart, Binette, Alexa Pichet, Blennow, Kaj, Boada, Merce, Boecker, Henning, Bottlaender, Michel, Den Braber, Anouk, Brooks, David J., Van Buchem, Mark A., Camus, Vincent, Carill, Jose Manuel, Cerman, Jiri, Chen, Kewei, Chételat, Gaël, Chipi, Elena, Cohen, Ann D., Daniels, Alisha, Delarue, Marion, Didic, Mira, Drzezga, Alexander, Dubois, Bruno, Eckerström, Marie, Ekblad, Laura L., Engelborghs, Sebastiaan, Epelbaum, Stéphane, Fagan, Anne M., Fan, Yong, Fladby, Tormod, Fleisher, Adam S., Van Der Flier, Wiesje M., Förster, Stefan, Fortea, Juan, Frederiksen, Kristian Steen, Freund-Levi, Yvonne, Frings, Lars, Frisoni, Giovanni B., Fröhlich, Lutz, Gabryelewicz, Tomasz, Gertz, Hermann Josef, Gill, Kiran Dip, Gkatzima, Olymbia, Gómez-Tortosa, Estrella, Grimmer, Timo, Guedj, Eric, Habeck, Christian G., Hampel, Harald, Handels, Ron, Hansson, Oskar, Hausner, Lucrezia, Hellwig, Sabine, Heneka, Michael T., Herukka, Sanna Kaisa, Hildebrandt, Helmut, Hodges, John, Hort, Jakub, Huang, Chin Chang, Iriondo, Ane Juaristi, Itoh, Yoshiaki, Ivanoiu, Adrian, Jagust, William J., Jessen, Frank, Johannsen, Peter, Johnson, Keith A., Kandimalla, Ramesh, Kapaki, Elisabeth N., Kern, Silke, Kilander, Lena, Klimkowicz-Mrowiec, Aleksandra, Klunk, William E., Koglin, Norman, Kornhuber, Johannes, Kramberger, Milica G., Kuo, Hung Chou, Van Laere, Koen, Landau, Susan M., Landeau, Brigitte, Lee, Dong Young, De Leon, Mony, Leyton, Cristian E., Lin, Kun Ju, Lleó, Alberto, Löwenmark, Malin, Madsen, Karine, Maier, Wolfgang, Marcusson, Jan, Marquié, Marta, Martinez-Lage, Pablo, Maserejian, Nancy, Mattsson, Niklas, De Mendonça, Alexandre, Meyer, Philipp T., Miller, Bruce L., Minatani, Shinobu, Mintun, Mark A., Mok, Vincent C.T., Molinuevo, Jose Luis, Morbelli, Silvia Daniela, Morris, John C., Mroczko, Barbara, Na, Duk L., Newberg, Andrew, Nobili, Flavio, Nordberg, Agneta, Olde Rikkert, Marcel G.M., De Oliveira, Catarina Resende, Olivieri, Pauline, Orellana, Adela, Paraskevas, George, Parchi, Piero, Pardini, Matteo, Parnetti, Lucilla, Peters, Oliver, Poirier, Judes, Popp, Julius, Prabhakar, Sudesh, Rabinovici, Gil D., Ramakers, Inez H., Rami, Lorena, Reiman, Eric M., Rinne, Juha O., Rodrigue, Karen M., Rodríguez-Rodriguez, Eloy, Roe, Catherine M., Rosa-Neto, Pedro, Rosen, Howard J., Rot, Uros, Rowe, Christopher C., Rüther, Eckart, Ruiz, Agustín, Sabri, Osama, Sakhardande, Jayant, Sánchez-Juan, Pascual, Sando, Sigrid Botne, Santana, Isabel, Sarazin, Marie, Scheltens, Philip, Schröder, Johannes, Selnes, Per, Seo, Sang Won, Silva, Dina, Skoog, Ingmar, Snyder, Peter J., Soininen, Hilkka, Sollberger, Marc, Sperling, Reisa A., Spiru, Luisa, Stern, Yaakov, Stomrud, Erik, Takeda, Akitoshi, Teichmann, Marc, Teunissen, Charlotte E., Thompson, Louisa I., Tomassen, Jori, Tsolaki, Magda, Vandenberghe, Rik, Verbeek, Marcel M., Verhey, Frans R.J., Villemagne, Victor, Villeneuve, Sylvia, Vogelgsang, Jonathan, Waldemar, Gunhild, Wallin, Anders, Wallin, Åsa K., Wiltfang, Jens, Wolk, David A., Yen, Tzu Chen, Zboch, Marzena, and Zetterberg, Henrik

Abstract

Importance: One characteristic histopathological event in Alzheimer disease (AD) is cerebral amyloid aggregation, which can be detected by biomarkers in cerebrospinal fluid (CSF) and on positron emission tomography (PET) scans. Prevalence estimates of amyloid pathology are important for health care planning and clinical trial design. Objective: To estimate the prevalence of amyloid abnormality in persons with normal cognition, subjective cognitive decline, mild cognitive impairment, or clinical AD dementia and to examine the potential implications of cutoff methods, biomarker modality (CSF or PET), age, sex, APOE genotype, educational level, geographical region, and dementia severity for these estimates. Design, Setting, and Participants: This cross-sectional, individual-participant pooled study included participants from 85 Amyloid Biomarker Study cohorts. Data collection was performed from January 1, 2013, to December 31, 2020. Participants had normal cognition, subjective cognitive decline, mild cognitive impairment, or clinical AD dementia. Normal cognition and subjective cognitive decline were defined by normal scores on cognitive tests, with the presence of cognitive complaints defining subjective cognitive decline. Mild cognitive impairment and clinical AD dementia were diagnosed according to published criteria. Exposures: Alzheimer disease biomarkers detected on PET or in CSF. Main Outcomes and Measures: Amyloid measurements were dichotomized as normal or abnormal using cohort-provided cutoffs for CSF or PET or by visual reading for PET. Adjusted data-driven cutoffs for abnormal amyloid were calculated using gaussian mixture modeling. Prevalence of amyloid abnormality was estimated according to age, sex, cognitive status, biomarker modality, APOE carrier status, educational level, geographical location, and dementia severity using generalized estimating equations. Results: Among the 19097 participants (mean [SD] age, 69.1 [9.8] years; 10148 women [53.1%])

Published
2022

49. Traduction et republication de : « Limiter l’augmentation globale de la température, restaurer la biodiversité et protéger la santé : appel pour une action urgente »

Author

Atwoli, Lukoye, primary, Baqui, Abdullah H., additional, Benfield, Thomas, additional, Bosurgi, Raffaella, additional, Godlee, Fiona, additional, Hancocks, Stephen, additional, Horton, Richard, additional, Laybourn-Langton, Laurie, additional, Monteiro, Carlos Augusto, additional, Norman, Ian, additional, Patrick, Kirsten, additional, Praities, Nigel, additional, Olde Rikkert, Marcel G.M., additional, Rubin, Eric J., additional, Sahni, Peush, additional, Smith, Richard, additional, Talley, Nicholas J., additional, Turale, Sue, additional, and Vázquez, Damián, additional

Published
2021
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