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The utility of delayed-enhancement (DE) has been extensively studied in patients with sarcoidosis who are asymptomatic or at low risk for cardiac involvement. However, there is lack of data regarding the utility of DE in patients with sarcoidosis who present with high grade cardiovascular symptoms. Also, the utility of T2-weighted imaging has not been evaluated in these patients.

Summary Different cardiac MR acquisition sequences have been used to obtain myocardial T1 values. Among which available techniques, MOdified Look-Locker Inversionrecovery (MOLLI) and inversion-recovery TrueFisp (TI scout) sequences are widely used in research and clinical settings. We compared myocardial T1 values derived from both MOLLI and TI scout techniques in the post gadolinium delayed enhancement experiments in a large-scale multicenter study (Multi-Ethnic Study of Atherosclerosis, MESA). Our results indicated that myocardial T1 measurement using MOLLI is reproducible with TI scout. Background Different cardiac MR sequences have been used to obtain myocardial T1 values. The multipoint approach, as first described by Look and Locker (TI scout), has been widely used for estimation of the optimal TI in the assessment of myocardial delayed enhancement (DE). The other technique, MOdified Look-Locker Inversionrecovery (MOLLI) allows a rapid and highly reproducible T1 mapping of the heart with high levels of intra and inter-observer agreement. Even though each technique claims its own merit and reliability, the post-contrast myocardial T1 value is confounded by various factors that inhibit comparison of myocardial T1 between patients. In this work, we compared myocardial T1 values derived from both MOLLI and TI scout

ObjectivesWe sought to evaluate whether transient myocardial systolic impairment in stress cardiomyopathy is associated with myocardial edema.BackgroundThe mechanisms of stress cardiomyopathy are still debated. T2 mapping in cardiac MRI (CMR) examination allows quantification of myocardial edema. The aim of the study was to detect and quantify transient myocardial edema in systolic dysfunctional myocardial segments in this setting.MethodsWe conducted a retrospective study of 6 patients presenting confirmed stress cardiomyopathy. CMR results of patients were compared with results of 11 healthy volunteers (control group). All examinations were performed in acute phase: left ventricle long axis T2 mapping sequence and dynamic sequences in the 3 axis of heart and delayed enhancement (DE) sequences 10 minutes after 0.2mmol/kg body weight of Gd-DTPA. A second CMR was performed in 4 patients after a delay >2 months.ResultsNo abnormal DE was observed. All systolic dysfunction recovered on follow-up. In acute phase, apical systolic dysfunction was observed in all patients. Mean T2 values of hypo- or akinetic segments were significantly higher than those of normokinetic segments (88.7±22.7ms vs. 55.4±7.7ms; p

Background To examine the diagnostic accuracy of cardiac magnetic resonance imaging (CMR) in differentiating thrombus from myxoma Thrombus is thought not to enhance on CMR, myxomas are thought to show mild heterogenous enhancement on delayed imaging. It is sometimes difficult to differentiate them, and this may lead to misdiagnosis, which would significantly impact treatment. Thrombi can have varying signal intensities depending on their age and fibrous composition in T1 and T2 imaging.

Summary The aim of this study was to assess the feasibility of navigator-gated 3D fat-suppressed delayed-enhancement CMR (DE-CMR) for simultaneous assessment of the myocardial scar and coronary artery disease, by comparing with 2D DE-CMR, CT, and CAG. Background Simultaneous assessment of myocardial scar or perfusion reduction and coronary artery stenosis is currently performed by side-by-side comparison or image fusion using coronary CTA and myocardial perfusion study, but the misregistration and differences in spatial resolution between imaging methods can be problematic. A CMR technique that can visualize both myocardial scar and coronary artery disease during a single examination may resolve this problem. Methods

Introduction Quantification of infarct size is important in the assessment of myocardial infarction (MI) and is commonly performed by ex-vivo staining in experimental studies [1]. Delayed-enhancement (DE) is an accurate method for assessing infarct in-vivo in humans, and is increasingly used in experimental studies of chronic MI where its accuracy has been well validated [2]. However, the feasibility and accuracy of DE-MRI in measuring infarct during the hyperacute MI phase (i.e. hours) is less well-defined. Additionally, while inversion recovery (IR) is the MR sequence of choice clinically, its role has not been fully explored in small animal models.