15,374 results on '"A, Donath"'
Search Results
52. Appendices
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Müller, Marion, Pfeil, Patricia, Dengel, Udo, Donath, Lisa, Müller, Marion, Pfeil, Patricia, Dengel, Udo, and Donath, Lisa
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- 2023
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53. Middle Class as the Study Group
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Müller, Marion, Pfeil, Patricia, Dengel, Udo, Donath, Lisa, Müller, Marion, Pfeil, Patricia, Dengel, Udo, and Donath, Lisa
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- 2023
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54. Identity/Identity Work
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Müller, Marion, Pfeil, Patricia, Dengel, Udo, Donath, Lisa, Müller, Marion, Pfeil, Patricia, Dengel, Udo, and Donath, Lisa
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- 2023
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55. Research Process and Methodological Approach
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Müller, Marion, Pfeil, Patricia, Dengel, Udo, Donath, Lisa, Müller, Marion, Pfeil, Patricia, Dengel, Udo, and Donath, Lisa
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- 2023
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56. Introduction
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Müller, Marion, Pfeil, Patricia, Dengel, Udo, Donath, Lisa, Müller, Marion, Pfeil, Patricia, Dengel, Udo, and Donath, Lisa
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- 2023
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57. Das verborgene Grundrecht – Ein Beitrag zur Entscheidung des Bundesverfassungsgerichts vom 19.11.2021 (Bundesnotbremse II) sowie zur Systematik der UN-Kinderrechtskonvention
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Donath, Philipp B., Donath, Philipp B., editor, Heger, Alexander, editor, Malkmus, Moritz, editor, and Bayrak, Orhan, editor
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- 2023
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58. Funding the Fundamentals
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Donath, David A.
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- 2023
59. Does Professional Development Effectively Support the Implementation of Inclusive Education? A Meta-Analysis
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Donath, Johanna L., Lüke, Timo, Graf, Elisabeth, Tran, Ulrich S., and Götz, Thomas
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Inclusive education is a reform aimed at educating all students in general classrooms, independent of diversity features such as special educational needs, giftedness, or migration. Its successful implementation requires teachers with professional knowledge about inclusive education, skills to address the diverse needs in the classroom, and positive beliefs toward inclusive education. Teachers are provided with professional development opportunities, but are these effective in improving their learning process and positively impacting students' behavior? We conducted a meta-analysis to address this question. The screening of 12,050 search results revealed 342 eligible studies with more than 155,000 participants and 1123 effects from four outcome categories: teachers' knowledge, skills, and beliefs and students' behavior. We observed positive, though varying, effects on all four outcome categories: large effects on teachers' knowledge regarding inclusive education (g = 0.93), moderate effects on teachers' skills (g = 0.49), small effects on teachers' beliefs (g = 0.23), and small-to-moderate effects on student behavior (g = 0.37). We also examined factors that might explain the differences in the strength of training effects. The data suggest that long-term training with high practical relevance and active learning opportunities facilitates transfer to schools.
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- 2023
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60. Resilient Warriors: An Expressive Arts-Based Resiliency Program to Promote Rural Upper Elementary Students' Resilience and Well-Being
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Ermis-Demirtas, Hulya, Donath, Jami, Weber, Laura, Bradley, Nicole, and Rizzo, Nicole
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A considerable gap exists between rural and urban children in their mental health outcomes that has continued to grow during the COVID-19 pandemic. Given the critical role of school counselors in addressing this gap, we tested the effectiveness of a 10-week, expressive arts-based resiliency program, Resilient Warriors, with 46 rural elementary students. Results revealed a significant increase in students' resilience and well-being posttest scores. We discuss practical implications for school counseling practitioners.
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- 2023
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61. Coaches’ Perceptions of Factors Driving Training Adaptation: An International Survey
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Anyadike-Danes, Kechi, Donath, Lars, and Kiely, John
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- 2023
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62. Cystine/glutamate antiporter System xc- deficiency impairs insulin secretion in mice
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de Baat, Axel, Meier, Daniel T., Rachid, Leila, Fontana, Adriano, Böni-Schnetzler, Marianne, and Donath, Marc Y.
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- 2023
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63. Intensity- and time-matched acute interval and continuous endurance exercise similarly induce an anti-inflammatory environment in recreationally active runners: focus on PD-1 expression in Tregs and the IL-6/IL-10 axis
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Proschinger, Sebastian, Schenk, Alexander, Weßels, Inga, Donath, Lars, Rappelt, Ludwig, Metcalfe, Alan J., and Zimmer, Philipp
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- 2023
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64. Contributors to post-operative venous thromboembolism risk after breast cancer surgery: A systematic review and meta-analysis
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Ahmed, Syeda Hoorulain, Shekouhi, Ramin, Gerhold, Cameron, Mattia, Alexzandra, Azizi, Armina, Donath, Gary, and Chim, Harvey
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- 2024
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65. Cardiorespiratory fitness, perceived fitness and autonomic function in in-patients with different depression severity compared with healthy controls
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Kreppke, Jan-Niklas, Cody, Robyn, Beck, Johannes, Brand, Serge, Donath, Lars, Eckert, Anne, Imboden, Christian, Hatzinger, Martin, Holsboer-Trachsler, Edith, Lang, Undine E., Mans, Sarah, Mikoteit, Thorsten, Oswald, Anja, Rogausch, Anja, Schweinfurth-Keck, Nina, Zahner, Lukas, Gerber, Markus, and Faude, Oliver
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- 2024
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66. Adiposity, immunity, and inflammation: interrelationships in health and disease: a report from 24th Annual Harvard Nutrition Obesity Symposium, June 2023
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Burak, Mehmet Furkan, Stanley, Takara L, Lawson, Elizabeth A, Campbell, Sophia L, Lynch, Lydia, Hasty, Alyssa H, Domingos, Ana I, Dixit, Vishwa D, Hotamışlıgil, Gökhan S, Sheedy, Frederick J, Dixon, Anne E, Brinkley, Tina E, Hill, Joseph A, Donath, Marc Y, and Grinspoon, Steven K
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- 2024
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67. Standardized Formats for Gamma-Ray Analysis Applied to HAWC Observatory Data
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Olivera-Nieto, Laura, Joshi, Vikas, Schoorlemmer, Harm, and Donath, Axel
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Astrophysics - Instrumentation and Methods for Astrophysics ,Astrophysics - High Energy Astrophysical Phenomena - Abstract
A wide range of data formats and proprietary software have traditionally been used in gamma-ray astronomy, usually developed for a single specific mission or experiment. However, in recent years there has been an increasing effort towards making astronomical data open and easily accessible. Within the gamma-ray community this has translated to the creation of a common data format across different gamma-ray observatories: the "gamma-astro-data-format" (GADF). Based on a similar premise, open-source analysis packages, such as Gammapy, are being developed and aim to provide a single, robust tool which suits the needs of many experiments at once. In this contribution we show that data from the High-Altitude Water Cherenkov (HAWC) observatory can be made compatible with the GADF and present the first GADF-based production of event lists and instrument response functions for a ground-based wide-field instrument. We use these data products to reproduce with excellent agreement the published HAWC Crab spectrum using Gammapy. Having a common data format and analysis tools facilitates joint analysis between different experiments and effective data sharing. This will be especially important for next-generation instruments, such as the proposed Southern Wide-field Gamma-ray Observatory (SWGO) and the planned Cherenkov Telescope Array (CTA)., Comment: Submitted at the 37th International Cosmic Ray conference (ICRC 2021) under the reference PoS(ICRC2021)727
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- 2021
68. LMC N132D: A mature supernova remnant with a power-law gamma-ray spectrum extending beyond 8 TeV
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Collaboration, H. E. S. S., Abdalla, H., Aharonian, F., Benkhali, F. Ait, Angüner, E. O., Arcaro, C., Armand, C., Armstrong, T., Ashkar, H., Backes, M., Baghmanyan, V., Martins, V. Barbosa, Barnacka, A., Barnard, M., Becherini, Y., Berge, D., Bernlöhr, K., Bi, B., Böttcher, M., Boisson, C., Bolmont, J., de Lavergne, M. de Bony, Breuhaus, M., Brun, F., Brun, P., Bryan, M., Büchele, M., Bulik, T., Bylund, T., Caroff, S., Carosi, A., Casanova, S., Chand, T., Chandra, S., Chen, A., Cotter, G., Curyło, M., Mbarubucyeye, J. Damascene, Davids, I. D., Davies, J., Deil, C., Devin, J., Dirson, L., Djannati-Atai, A., Dmytriiev, A., Donath, A., Doroshenko, V., Dreyer, L., Duffy, C., Dyks, J., Egberts, K., Eichhorn, F., Einecke, S., Emery, G., Ernenwein, J. -P., Feijen, K., Fegan, S., Fiasson, A., de Clairfontaine, G. Fichet, Fontaine, G., Funk, S., Füßling, M., Gabici, S., Gallant, Y. A., Giavitto, G., Giunti, L., Glawion, D., Glicenstein, J. F., Grondin, M. -H., Hahn, J., Haupt, M., Hermann, G., Hinton, J. A., Hofmann, W., Hoischen, C., Holch, T. L., Holler, M., Hörbe, M., Horns, D., Huber, D., Jamrozy, M., Jankowsky, D., Jankowsky, F., Jardin-Blicq, A., Joshi, V., Jung-Richardt, I., Kasai, E., Kastendieck, M. A., Katarzynski, K., Katz, U., Khangulyan, D., Khélifi, B., Klepser, S., Kluźniak, W., Komin, Nu., Konno, R., Kosack, K., Kostunin, D., Kreter, M., Lamanna, G., Lemière, A., Lemoine-Goumard, M., Lenain, J. -P., Leuschner, F., Levy, C., Lohse, T., Lypova, I., Mackey, J., Majumdar, J., Malyshev, D., Marandon, V., Marchegiani, P., Marcowith, A., Mares, A., Martí-Devesa, G., Marx, R., Maurin, G., Meintjes, P. J., Meyer, M., Mitchell, A., Moderski, R., Mohrmann, L., Montanari, A., Moore, C., Morris, P., Moulin, E., Muller, J., Murach, T., Nakashima, K., Nayerhoda, A., de Naurois, M., Ndiyavala, H., Niemiec, J., Oakes, L., O'Brien, P., Odaka, H., Ohm, S., Olivera-Nieto, L., Wilhelmi, E. de Ona, Ostrowski, M., Panny, S., Panter, M., Parsons, R. D., Peron, G., Peyaud, B., Piel, Q., Pita, S., Poireau, V., Noel, A. Priyana, Prokhorov, D. A., Prokoph, H., Pühlhofer, G., Punch, M., Quirrenbach, A., Raab, S., Rauth, R., Reichherzer, P., Reimer, A., Reimer, O., Remy, Q., Renaud, M., Rieger, F., Rinchiuso, L., Romoli, C., Rowell, G., Rudak, B., Ruiz-Velasco, E., Sahakian, V., Sailer, S., Salzmann, H., Sanchez, D. A., Santangelo, A., Sasaki, M., Scalici, M., Schäfer, J., Schüssler, F., Schutte, H. M., Schwanke, U., Seglar-Arroyo, M., Senniappan, M., Seyffert, A. S., Shafi, N., Shapopi, J. N. S., Shiningayamwe, K., Simoni, R., Sinha, A., Sol, H., Specovius, A., Spencer, S., Spir-Jacob, M., Stawarz, L., Sun, L., Steenkamp, R., Stegmann, C., Steinmassl, S., Steppa, C., Takahashi, T., Tavernier, T., Taylor, A. M., Terrier, R., Thiersen, J. H. E., Tiziani, D., Tluczykont, M., Tomankova, L., Trichard, C., Tsirou, M., Tuffs, R., Uchiyama, Y., van der Walt, D. J., van Eldik, C., van Rensburg, C., van Soelen, B., Vasileiadis, G., Veh, J., Venter, C., Vincent, P., Vink, J., Völk, H. J., Wadiasingh, Z., Wagner, S. J., Watson, J., Werner, F., White, R., Wierzcholska, A., Wong, Yu Wun, Yusafzai, A., Zacharias, M., Zanin, R., Zargaryan, D., Zdziarski, A. A., Zech, A., Zhu, S. J., Zorn, J., Zouari, S., and Żywucka, N.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
We analyzed 252 hours of High Energy Stereoscopic System (H.E.S.S.) observations towards the supernova remnant (SNR) LMC N132D that were accumulated between December 2004 and March 2016 during a deep survey of the Large Magellanic Cloud, adding 104 hours of observations to the previously published data set to ensure a > 5 sigma detection. To broaden the gamma-ray spectral coverage required for modeling the spectral energy distribution, an analysis of Fermi-LAT Pass 8 data was also included. We unambiguously detect N132D at very high energies (VHE) with a significance of 5.7 sigma. We report the results of a detailed analysis of its spectrum and localization based on the extended H.E.S.S. data set. The joint analysis of the extended H.E.S.S and Fermi-LAT data results in a spectral energy distribution in the energy range from 1.7 GeV to 14.8 TeV, which suggests a high luminosity of N132D at GeV and TeV energies. We set a lower limit on a gamma-ray cutoff energy of 8 TeV with a confidence level of 95%. The new gamma-ray spectrum as well as multiwavelength observations of N132D when compared to physical models suggests a hadronic origin of the VHE gamma-ray emission. SNR N132D is a VHE gamma-ray source that shows a spectrum extending to the VHE domain without a spectral cutoff at a few TeV, unlike the younger oxygen-rich SNR Cassiopeia A. The gamma-ray properties of N132D may be affected by an interaction with a nearby molecular cloud that partially lies inside the 95% confidence region of the source position. [Abridged], Comment: Accepted for publication in Astronomy & Astrophysics
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- 2021
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69. TeV emission of Galactic plane sources with HAWC and H.E.S.S
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Abdalla, H., Aharonian, F., Benkhali, F. Ait, Angüner, E. O., Arcaro, C., Armand, C., Armstrong, T., Ashkar, H., Backes, M., Baghmanyan, V., Martins, V. Barbosa, Barnacka, A., Barnard, M., Becherini, Y., Berge, D., Bernlöhr, K., Bi, B., Böttcher, M., Boisson, C., Bolmont, J., de Lavergne, M. de Bony, Breuhaus, M., Brose, R., Brun, F., Brun, P., Bryan, M., Büchele, M., Bulik, T., Bylund, T., Caroff, S., Carosi, A., Chand, T., Chandra, S., Chen, A., Cotter, G., Curyło, M., Mbarubucyeye, J. Damascene, Davids, I. D., Davies, J., Deil, C., Devin, J., Dirson, L., Djannati-Ataï, A., Dmytriiev, A., Donath, A., Doroshenko, V., Dreyer, L., Duffy, C., Dyks, J., Egberts, K., Eichhorn, F., Einecke, S., Emery, G., Ernenwein, J. -P., Feijen, K., Fegan, S., Fiasson, A., de Clairfontaine, G. Fichet, Fontaine, G., Funk, S., Füßling, M., Gabici, S., Gallant, Y. A., Giavitto, G., Giunti, L., Glawion, D., Glicenstein, J. F., Gottschall, D., Grondin, M. -H., Hahn, J., Haupt, M., Hermann, G., Hinton, J. A., Hofmann, W., Hoischen, C., Holch, T. L., Holler, M., Hörbe, M., Horns, D., Huber, D., Jamrozy, M., Jankowsky, D., Jankowsky, F., Jung-Richardt, I., Kasai, E., Kastendieck, M. A., Katarzyński, K., Katz, U., Khangulyan, D., Khélifi, B., Klepser, S., Kluźniak, W., Komin, Nu., Konno, R., Kosack, K., Kostunin, D., Kreter, M., Lamanna, G., Lemière, A., Lemoine-Goumard, M., Lenain, J. -P., Leuschner, F., Levy, C., Lohse, T., Lypova, I., Mackey, J., Majumdar, J., Malyshev, D., Marandon, V., Marchegiani, P., Marcowith, A., Mares, A., Martí-Devesa, G., Marx, R., Maurin, G., Meintjes, P. J., Meyer, M., Mitchell, A. M. W., Moderski, R., Mohrmann, L., Montanari, A., Moore, C., Morris, P., Moulin, E., Muller, J., Murach, T., Nakashima, K., Nayerhoda, A., de Naurois, M., Ndiyavala, H., Niemiec, J., Oakes, L., Brien, P. O, Odaka, H., Ohm, S., Olivera-Nieto, L., Wilhelmi, E. de Ona, Ostrowski, M., Panny, S., Panter, M., Parsons, R. D., Peron, G., Peyaud, B., Piel, Q., Pita, S., Poireau, V., Noel, A. Priyana, Prokhorov, D. A., Prokoph, H., Pühlhofer, G., Punch, M., Quirrenbach, A., Raab, S., Rauth, R., Reichherzer, P., Reimer, A., Reimer, O., Remy, Q., Renaud, M., Rieger, F., Rinchiuso, L., Romoli, C., Rowell, G., Rudak, B., Sahakian, V., Sailer, S., Salzmann, H., Sanchez, D. A., Santangelo, A., Sasaki, M., Schäfer, J., Schüssler, F., Schutte, H. M., Schwanke, U., Seglar-Arroyo, M., Senniappan, M., Seyffert, A. S., Shafi, N., Shapopi, J. N. S., Shiningayamwe, K., Simoni, R., Sinha, A., Sol, H., Specovius, A., Spencer, S., Spir-Jacob, M., Stawarz, Ł., Sun, L., Steenkamp, R., Stegmann, C., Steinmassl, S., Steppa, C., Takahashi, T., Tavernier, T., Taylor, A. M., Terrier, R., Thiersen, J. H. E., Tiziani, D., Tluczykont, M., Tomankova, L., Trichard, C., Tsirou, M., Tuffs, R., Uchiyama, Y., van der Walt, D. J., van Eldik, C., van Rensburg, C., van Soelen, B., Vasileiadis, G., Veh, J., Venter, C., Vincent, P., Vink, J., Völk, H. J., Wadiasingh, Z., Wagner, S. J., Watson, J., Werner, F., White, R., Wierzcholska, A., Wong, Yu Wun, Yusafzai, A., Zacharias, M., Zanin, R., Zargaryan, D., Zdziarski, A. A., Zech, A., Zhu, S. J., Zmija, A., Zorn, J., Zouari, S., Żywucka, N., Albert, A., Alfaro, R., Alvarez, C., Arteaga-Velázquez, J. C., Arunbabu, K. P., Rojas, D. Avila, Belmont-Moreno, E., BenZvi, S. Y., Brisbois, C., Caballero-Mora, K. S., Capistrán, T., Carramiñana, A., Casanova, S., Cotti, U., Cotzomi, J., de León, S. Coutiño, De la Fuente, E., de León, C., Hernandez, R. Diaz, Díaz-Vélez, J. C., Dingus, B. L., DuVernois, M. A., Durocher, M., Ellsworth, R. W., Engel, K., Espinoza, C., Fan, K. L., Alonso, M. Fernández, Fraija, N., Galván-Gámez, A., Garcia, D., García-González, J. A., Garfias, F., Giacinti, G., González, M. M., Goodman, J. A., Harding, J. P., Hernandez, S., Hona, B., Huang, D., Hueyotl-Zahuantitla, F., Hüntemeyer, P., Iriarte, A., Jardin-Blicq, A., Joshi, V., Kieda, D., Lee, W. H., Vargas, H. León, Linnemann, J. T., Longinotti, A. L., Luis-Raya, G., López-Coto, R., Malone, K., Martinez, O., Martinez-Castellanos, I., Martínez-Castro, J., Matthews, J. A., Miranda-Romagnoli, P., Morales-Soto, J. A., Moreno, E., Mostafá, M., Nellen, L., Newbold, M., Nisa, M. U., Noriega-Papaqui, R., Omodei, N., Peisker, A., Araujo, Y. Pérez, Pérez-Pérez, E. G., Rho, C. D., Rosa-González, D., Ruiz-Velasco, E., Greus, F. Salesa, Sandoval, A., Schneider, M., Schoorlemmer, H., Serna-Franco, J., Smith, A. J., Springer, R. W., Surajbali, P., Tollefson, K., Torres, I., Torres-Escobedo, R., Turner, R., Ureña-Mena, F., Villaseñor, L., Weisgarber, T., Willox, E., and Zhou, H.
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Astrophysics - Instrumentation and Methods for Astrophysics - Abstract
The High Altitude Water Cherenkov (HAWC) observatory and the High Energy Stereoscopic System (H.E.S.S.) are two leading instruments in the ground-based very-high-energy gamma-ray domain. HAWC employs the water Cherenkov detection (WCD) technique, while H.E.S.S. is an array of Imaging Atmospheric Cherenkov Telescopes (IACTs). The two facilities therefore differ in multiple aspects, including their observation strategy, the size of their field of view and their angular resolution, leading to different analysis approaches. Until now, it has been unclear if the results of observations by both types of instruments are consistent: several of the recently discovered HAWC sources have been followed up by IACTs, resulting in a confirmed detection only in a minority of cases. With this paper, we go further and try to resolve the tensions between previous results by performing a new analysis of the H.E.S.S. Galactic plane survey data, applying an analysis technique comparable between H.E.S.S. and HAWC. Events above 1 TeV are selected for both datasets, the point spread function of H.E.S.S. is broadened to approach that of HAWC, and a similar background estimation method is used. This is the first detailed comparison of the Galactic plane observed by both instruments. H.E.S.S. can confirm the gamma-ray emission of four HAWC sources among seven previously undetected by IACTs, while the three others have measured fluxes below the sensitivity of the H.E.S.S. dataset. Remaining differences in the overall gamma-ray flux can be explained by the systematic uncertainties. Therefore, we confirm a consistent view of the gamma-ray sky between WCD and IACT techniques.
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- 2021
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70. Evidence of 100 TeV $\gamma$-ray emission from HESS J1702-420: A new PeVatron candidate
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Abdalla, H., Aharonian, F., Benkhali, F. Ait, Angüner, E. O., Arcaro, C., Armand, C., Armstrong, T., Ashkar, H., Backes, M., Baghmanyan, V., Martins, V. Barbosa, Barnacka, A., Barnard, M., Becherini, Y., Berge, D., Bernlöhr, K., Bi, B., Böttcher, M., Boisson, C., Bolmont, J., de Lavergne, M. de Bony, Breuhaus, M., Brun, F., Brun, P., Bryan, M., Büchele, M., Bulik, T., Bylund, T., Caroff, S., Carosi, A., Casanova, S., Chand, T., Chandra, S., Chen, A., Cotter, G., Curyło, M., Mbarubucyeye, J. Damascene, Davids, I. D., Davies, J., Deil, C., Devin, J., Dirson, L., Djannati-Atai, A., Dmytriiev, A., Donath, A., Doroshenko, V., Dreyer, L., Duffy, C., Dyks, J., Egberts, K., Eichhorn, F., Einecke, S., Emery, G., Ernenwein, J. -P., Feijen, K., Fegan, S., Fiasson, A., de Clairfontaine, G. Fichet, Fontaine, G., Funk, S., Füßling, M., Gabici, S., Gallant, Y. A., Giavitto, G., Giunti, L., Glawion, D., Glicenstein, J. F., Grondin, M. -H., Hahn, J., Haupt, M., Hermann, G., Hinton, J. A., Hofmann, W., Hoischen, C., Holch, T. L., Holler, M., Hörbe, M., Horns, D., Huber, D., Jamrozy, M., Jankowsky, D., Jankowsky, F., Jardin-Blicq, A., Joshi, V., Jung-Richardt, I., Kasai, E., Kastendieck, M. A., Katarzynski, K., Katz, U., Khangulyan, D., Khélifi, B., Klepser, S., Kluźniak, W., Komin, Nu., Konno, R., Kosack, K., Kostunin, D., Kreter, M., Lamanna, G., Lemière, A., Lemoine-Goumard, M., Lenain, J. -P., Leuschner, F., Levy, C., Lohse, T., Lypova, I., Mackey, J., Majumdar, J., Malyshev, D., Marandon, V., Marchegiani, P., Marcowith, A., Mares, A., Martí-Devesa, G., Marx, R., Maurin, G., Meintjes, P. J., Meyer, M., Mitchell, A., Moderski, R., Mohrmann, L., Montanari, A., Moore, C., Morris, P., Moulin, E., Muller, J., Murach, T., Nakashima, K., Nayerhoda, A., de Naurois, M., Ndiyavala, H., Niemiec, J., Oakes, L., O'Brien, P., Odaka, H., Ohm, S., Olivera-Nieto, L., Wilhelmi, E. de Ona, Ostrowski, M., Panny, S., Panter, M., Parsons, R. D., Peron, G., Peyaud, B., Piel, Q., Pita, S., Poireau, V., Noel, A. Priyana, Prokhorov, D. A., Prokoph, H., Pühlhofer, G., Punch, M., Quirrenbach, A., Raab, S., Rauth, R., Reichherzer, P., Reimer, A., Reimer, O., Remy, Q., Renaud, M., Rieger, F., Rinchiuso, L., Romoli, C., Rowell, G., Rudak, B., Ruiz-Velasco, E., Sahakian, V., Sailer, S., Salzmann, H., Sanchez, D. A., Santangelo, A., Sasaki, M., Scalici, M., Schäfer, J., Schüssler, F., Schutte, H. M., Schwanke, U., Seglar-Arroyo, M., Senniappan, M., Seyffert, A. S., Shafi, N., Shapopi, J. N. S., Shiningayamwe, K., Simoni, R., Sinha, A., Sol, H., Specovius, A., Spencer, S., Spir-Jacob, M., Stawarz, L., Sun, L., Steenkamp, R., Stegmann, C., Steinmassl, S., Steppa, C., Takahashi, T., Tavernier, T., Taylor, A. M., Terrier, R., Thiersen, J. H. E., Tiziani, D., Tluczykont, M., Tomankova, L., Trichard, C., Tsirou, M., Tuffs, R., Uchiyama, Y., van der Walt, D. J., van Eldik, C., van Rensburg, C., van Soelen, B., Vasileiadis, G., Veh, J., Venter, C., Vincent, P., Vink, J., Völk, H. J., Wadiasingh, Z., Wagner, S. J., Watson, J., Werner, F., White, R., Wierzcholska, A., Wong, Yu Wun, Yusafzai, A., Zacharias, M., Zanin, R., Zargaryan, D., Zdziarski, A. A., Zech, A., Zhu, S. J., Zorn, J., Zouari, S., Żywucka, N., and Acero, F.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
The identification of PeVatrons, hadronic particle accelerators reaching the knee of the cosmic ray spectrum (few $10^{15}$ eV), is crucial to understand the origin of cosmic rays in the Galaxy. We provide an update on the unidentified source HESS J1702-420, a promising PeVatron candidate. We present new observations of HESS J1702-420 made with the High Energy Stereoscopic System (H.E.S.S.), and processed using improved analysis techniques. The analysis configuration was optimized to enhance the collection area at the highest energies. We applied a three-dimensional (3D) likelihood analysis to model the source region and adjust non thermal radiative spectral models to the $\gamma$-ray data. We also analyzed archival data from the Fermi Large Area Telescope (LAT) to constrain the source spectrum at $\gamma$-ray energies >10 GeV. We report the detection of a new source component called HESS J1702-420A, that was separated from the bulk of TeV emission at a $5.4\sigma$ confidence level. The power law $\gamma$-ray spectrum of HESS J1702-420A extends with an index of $\Gamma=1.53\pm0.19_\text{stat}\pm0.20_\text{sys}$ and without curvature up to the energy band 64-113 TeV, in which it was detected by H.E.S.S. at a $4.0\sigma$ confidence level. This brings evidence for the source emission up to $100\,\text{TeV}$, which makes HESS J1702-420A a compelling candidate site for the presence of extremely high energy cosmic rays. Remarkably, in a hadronic scenario, the cut-off energy of the proton distribution powering HESS J1702-420A is found to be higher than 0.5 PeV at a 95% confidence level. HESS J1702-420A becomes therefore one of the most solid PeVatron candidates detected so far in H.E.S.S. data, altough a leptonic origin of its emission could not be ruled out either., Comment: Accepted for publication in the 2. Astrophysical processes section of Astronomy & Astrophysics
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- 2021
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71. Search for dark matter annihilation signals from unidentified Fermi-LAT objects with H.E.S.S
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Collaboration, H. E. S. S., Abdallah, H., Aharonian, F., Benkhali, F. Ait, Angüner, E. O., Arcaro, C., Armand, C., Armstrong, T., Ashkar, H., Backes, M., Baghmanyan, V., Martins, V. Barbosa, Barnacka, A., Barnard, M., Becherini, Y., Berge, D., Bernlöhr, K., Bi, B., Böttcher, M., Boisson, C., Bolmont, J., de Lavergne, M. de Bony, Breuhaus, M., Brose, R., Brun, F., Bulik, T., Bylund, T., Cangemi, F., Caroff, S., Casanova, S., Chambery, P., Chand, J. Catalano T., Chen, A., Cotter, G., Curylo, M., Dalgleish, H., Mbarubucyeye, J. Damascene, Davids, I. D., Davies, J., Devin, J., Djannati-Ataï, A., Dmytriiev, A., Donath, A., Doroshenko, V., Dreyer, L., Plessis, L. Du, Duffy, C., Egberts, K., Einecke, S., Emery, G., Ernenwein, J. -P., Feijen, K., Fegan, S., Fiasson, A., de Clairfontaine, G. Fichet, Fontaine, G., Funk, S., Füßling, M., Gabici, S., Gallant, Y. A., Giavitto, G., Giunti, L., Glawion, D., Glicenstein, J. F., Grondin, M. -H., Hattingh, S., Haupt, M., Hermann, G., Hinton, J. A., Hofmann, W., Hoischen, C., Holch, T. L., Holler, M., Hörbe, M., Horns, D., Huang, Z., Huber, D., Jamrozy, M., Jankowsky, D., Jankowsky, F., Joshi, V., Jung-Richardt, I., Kasai, E., Katarzyński, K., Katz, U., Khangulyan, D., Khèlifi, B., Klepser, S., Kluzniak, W., Komin, Nu., Konno, R., Kosack, K., Kostunin, D., Kreter, M., Mezek, G. Kukec, Kundu, A., Lamanna, G., Stum, S. Le, Lemière, A., Lemoine-Goumard, M., Lenain, J. -P., Leuschner, F., Levy, C., Lohse, T., Luashvili, A., Lypova, I., Mackey, J., Majumdar, J., Malyshev, D., Marandon, V., Marchegiani, P., Marcowith, A., Mares, A., Martì-Devesa, G., Marx, R., Maurin, G., Meintjes, P. J., Meyer, M., Mitchell, A., Moderski, R., Mohrmann, L., Montanari, A., Moore, C., Morris, P., Moulin, E., Muller, J., Murach, T., Nakashima, K., Nayerhoda, A., de Naurois, M., Ndiyavala, H., Niemiec, J., Noel, A., Oberholzer, L., O'Brien, P., Ohm, S., Olivera-Nieto, L., Wilhelmi, E. de Ona, Ostrowski, M., Panter, M., Panny, S., Parsons, R. D., Peron, G., Pita, S., Poireau, V., Prokhorov, D. A., Prokoph, H., Pühlhofer, G., Punch, M., Quirrenbach, A., Reichherzer, P., Reimer, A., Reimer, O., Remy, Q., Renaud, M., Rieger, F., Romoli, C., Rowell, G., Rudak, B., Ricarte, H. Rueda, Ruiz-Velasco, E., Sahakian, V., Sailer, S., Salzmann, H., Sanchez, D. A., Santangelo, A., Sasaki, M., Schüssler, F., Schutte, H. M., Schwanke, U., Senniappan, M., Seyffert, A. S., Shapopi, J. N. S., Shiningayamwe, K., Simoni, R., Sinha, A., Sol, H., Spackman, H., Specovius, A., Spencer, S., Spir-Jacob, M., Stawarz, L., Sun, L., Steenkamp, R., Stegmann, C., Steinmassl, S., Steppa, C., Takahashi, T., Tanaka, T., Tavernier, T., Taylor, A. M., Terrier, R., Morgan, C. Thorpe, Thiersen, J. H. E., Tluczykont, M., Tomankova, L., Trichard, C., Tsirou, M., Tsuji, M., Tuffs, R., Uchiyama, Y., van der Walt, D. J., van Eldik, C., van Rensburg, C., van Soelen, B., Vasileiadis, G., Veh, J., Venter, C., Viana, A., Vincent, P., Vink, J., Völk, H. J., Wagner, S. J., Werner, F., White, R., Wierzcholska, A., Wong, Yu Wun, Yassin, H., Yusafzai, A., Zacharias, M., Zanin, R., Zargaryan, D., Zdziarski, A. A., Zech, A., Zhu, S., Zmija, A., Zorn, J., Zouari, S., and Zywucka, N.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
Cosmological $N$-body simulations show that Milky Way-sized galaxies harbor a population of unmerged dark matter subhalos. These subhalos could shine in gamma-rays and be eventually detected in gamma-ray surveys as unidentified sources. We performed a thorough selection among unidentified Fermi-LAT Objects (UFOs) to identify them as possible TeV-scale dark matter subhalo candidates. We search for very-high-energy (E $\gtrsim$ 100 GeV) gamma-ray emissions using H.E.S.S. observations towards four selected UFOs. Since no significant very-high-energy gamma-ray emission is detected in any dataset of the four observed UFOs nor in the combined UFO dataset, strong constraints are derived on the product of the velocity-weighted annihilation cross section $\langle \sigma v \rangle$ by the $J$-factor for the dark matter models. The 95% C.L. observed upper limits derived from combined H.E.S.S. observations reach $\langle \sigma v \rangle J$ values of 3.7$\times$10$^{-5}$ and 8.1$\times$10$^{-6}$ GeV$^2$cm$^{-2}$s$^{-1}$ in the $W^+W^-$ and $\tau^+\tau^-$ channels, respectively, for a 1 TeV dark matter mass. Focusing on thermal WIMPs, the H.E.S.S. constraints restrict the $J$-factors to lie in the range 6.1$\times$10$^{19}$ - 2.0$\times$10$^{21}$ GeV$^2$cm$^{-5}$, and the masses to lie between 0.2 and 6 TeV in the $W^+W^-$ channel. For the $\tau^+\tau^-$ channel, the $J$-factors lie in the range 7.0$\times$10$^{19}$ - 7.1$\times$10$^{20}$ GeV$^2$cm$^{-5}$ and the masses lie between 0.2 and 0.5 TeV. Assuming model-dependent predictions from cosmological N-body simulations on the $J$-factor distribution for Milky Way-sized galaxies, the dark matter models with masses greater than 0.3 TeV for the UFO emissions can be ruled out at high confidence level., Comment: 11 pages, 7 figures, matches accepted version in The Astrophysical Journal
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- 2021
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72. Search for dark matter annihilation in the dwarf irregular galaxy WLM with H.E.S.S
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Collaboration, H. E. S. S., Abdallah, H., Adam, R., Aharonian, F., Benkhali, F. Ait, Angüner, E. O., Arcaro, C., Armand, C., Armstrong, T., Ashkar, H., Backes, M., Baghmanyan, V., Martins, V. Barbosa, Barnacka, A., Barnard, M., Becherini, Y., Berge, D., Bernlöhr, K., Bi, B., Böttcher, M., Boisson, C., Bolmont, J., de Lavergne, M. de Bony, Breuhaus, M., Brun, F., Brun, P., Bryan, M., Büchele, M., Bulik, T., Bylund, T., Caroff, S., Carosi, A., Casanova, S., Chand, T., Chandra, S., Chen, A., Cotter, G., Curylo, M., Mbarubucyeye, J. Damascene, Davids, I. D., Davies, J., Deil, C., Devin, J., deWilt, P., Dirson, L., Djannati-Ataï, A., Dmytriiev, A., Donath, A., Doroshenko, V., Duffy, C., Dyks, J., Egberts, K., Eichhorn, F., Einecke, S., Emery, G., Ernenwein, J. -P., Feijen, K., Fegan, S., Fiasson, A., de Clairfontaine, G. Fichet, Fontaine, G., Funk, S., Füßling, M., Gabici, S., Gallant, Y. A., Giavitto, G., Giunti, L., Glawion, D., Glicenstein, J. F., Gottschall, D., Grondin, M. -H., Hahn, J., Haupt, M., Hermann, G., Hinton, J. A., Hofmann, W., Hoischen, C., Holch, T. L., Holler, M., Hörbe, M., Horns, D., Huber, D., Jamrozy, M., Jankowsky, D., Jankowsky, F., Jardin-Blicq, A., Joshi, V., Jung-Richardt, I., Kasai, E., Kastendieck, M. A., Katarzyński, K., Katz, U., Khangulyan, D., Khèlifi, B., Klepser, S., Kluzniak, W., Komin, Nu., Konno, R., Kosack, K., Kostunin, D., Kreter, M., Lamanna, G., Lemière, A., Lemoine-Goumard, M., Lenain, J. -P., Levy, C., Lohse, T., Lypova, I., Mackey, J., Majumdar, J., Malyshev, D., Marandon, V., Marchegiani, P., Marcowith, A., Mares, A., Martì-Devesa, G., Marx, R., Maurin, G., Meintjes, P. J., Meyer, M., Moderski, R., Mohamed, M., Mohrmann, L., Montanari, A., Moore, C., Morris, P., Moulin, E., Muller, J., Murach, T., Nakashima, K., Nayerhoda, A., de Naurois, M., Ndiyavala, H., Niederwanger, F., Niemiec, J., Oakes, L., O'Brien, P., Odaka, H., Ohm, S., Olivera-Nieto, L., Wilhelmi, E. de Ona, Ostrowski, M., Panter, M., Panny, S., Parsons, R. D., Peron, G., Peyaud, B., Piel, Q., Pita, S., Poireau, V., Noel, A. Priyana, Prokhorov, D. A., Prokoph, H., Pühlhofer, G., Punch, M., Quirrenbach, A., Raab, S., Rauth, R., Reichherzer, P., Reimer, A., Reimer, O., Remy, Q., Renaud, M., Rieger, F., Rinchiuso, L., Romoli, C., Rowell, G., Rudak, B., Ruiz-Velasco, E., Sahakian, V., Sailer, S., Sanchez, D. A., Santangelo, A., Sasaki, M., Scalici, M., Schüssler, F., Schutte, H. M., Schwanke, U., Schwemmer, S., Seglar-Arroyo, M., Senniappan, M., Seyffert, A. S., Shafi, N., Shiningayamwe, K., Simoni, R., Sinha, A., Sol, H., Specovius, A., Spencer, S., Spir-Jacob, M., Stawarz, L., Sun, L., Steenkamp, R., Stegmann, C., Steinmassl, S., Steppa, C., Takahashi, T., Tavernier, T., Taylor, A. M., Terrier, R., Tiziani, D., Tluczykont, M., Tomankova, L., Trichard, C., Tsirou, M., Tuffs, R., Uchiyama, Y., van der Walt, D. J., van Eldik, C., van Rensburg, C., van Soelen, B., Vasileiadis, G., Veh, J., Venter, C., Vincent, P., Vink, J., Völk, H. J., Vuillaume, T., Wadiasingh, Z., Wagner, S. J., Watson, J., Werner, F., White, R., Wierzcholska, A., Wong, Yu Wun, Yusafzai, A., Zacharias, M., Zanin, R., Zargaryan, D., Zdziarski, A. A., Zech, A., Zhu, S., Zorn, J., Zouari, S., and Zywucka, N.
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Astrophysics - High Energy Astrophysical Phenomena ,High Energy Physics - Experiment - Abstract
We search for an indirect signal of dark matter through very high-energy gamma rays from the Wolf-Lundmark-Melotte (WLM) dwarf irregular galaxy. The pair annihilation of dark matter particles would produce Standard Model particles in the final state such as gamma rays, which might be detected by ground-based Cherenkov telescopes. Dwarf irregular galaxies represent promising targets as they are dark matter dominated objects with well measured kinematics and small uncertainties on their dark matter distribution profiles. In 2018, the H.E.S.S. five-telescope array observed the dwarf irregular galaxy WLM for 18 hours. We present the first analysis based on data obtained from an imaging atmospheric Cherenkov telescope for this subclass of dwarf galaxy. As we do not observe any significant excess in the direction of WLM, we interpret the result in terms of constraints on the velocity-weighted cross section for dark matter pair annihilation as a function of the dark matter particle mass for various continuum channels as well as the prompt gamma-gamma emission. For the $\tau^+\tau^-$ channel the limits reach a $\langle \sigma v \rangle$ value of about $4\times 10^{-22}$ cm3s-1 for a dark matter particle mass of 1 TeV. For the prompt gamma-gamma channel, the upper limit reaches a $\langle \sigma v \rangle$ value of about $5 \times10^{-24}$ cm3s-1 for a mass of 370 GeV. These limits represent an improvement of up to a factor 200 with respect to previous results for the dwarf irregular galaxies for TeV dark matter search., Comment: 13 pages, 5 figures
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- 2021
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73. The Effect of Network Delay and Contagion on Mobile Banking Users: A Dynamical Analysis
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Liliana Eva Donath, Gabriela Mircea, Mihaela Neamțu, Grațiela Georgiana Noja, and Nicoleta Sîrghi
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dynamic system ,mathematical modelling ,mobile banking ,simulation ,control strategy ,contagion ,Mathematics ,QA1-939 - Abstract
This paper analyses how network contagion affects the acceptance or rejection of mobile banking, emphasizing the risk of contagion that hinders the growth of users among bank clients. As a research method, a mathematical model based on the Susceptible, Infected, and Recovered framework is used within a nonlinear dynamic system with a distributed time delay and the optimal control strategy. The approach aims to find the behaviour dynamics of mobile banking users, non-users, and undecided ones. Our model adds value to the existing literature by employing a qualitative dynamic analysis, as opposed to other studies that study contagion empirically. The steady states and their conditions for stability are found, and the critical value for time delay causing oscillatory is determined. The optimal control strategies are identified to enlarge the number of mobile banking users and decrease the number of non-users. Numerical simulations support the theoretical findings. The research has practical implications given that the model predicts mobile banking user behaviour in assisting policy decision-making and addresses the possible policy measures that aim to increase the number of mobile banking users. The conclusions suggest that financial inclusion can contribute to the expansion of mobile banking users.
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- 2024
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74. Inflammation in obesity, diabetes, and related disorders
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Rohm, Theresa V, Meier, Daniel T, Olefsky, Jerrold M, and Donath, Marc Y
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Biomedical and Clinical Sciences ,Immunology ,Nutrition ,Prevention ,Diabetes ,Obesity ,2.1 Biological and endogenous factors ,Metabolic and endocrine ,Inflammatory and immune system ,Animals ,Diabetes Complications ,Diabetes Mellitus ,Type 2 ,Humans ,Immunomodulation ,Inflammation ,Insulin Resistance - Abstract
Obesity leads to chronic, systemic inflammation and can lead to insulin resistance (IR), β-cell dysfunction, and ultimately type 2 diabetes (T2D). This chronic inflammatory state contributes to long-term complications of diabetes, including non-alcoholic fatty liver disease (NAFLD), retinopathy, cardiovascular disease, and nephropathy, and may underlie the association of type 2 diabetes with other conditions such as Alzheimer's disease, polycystic ovarian syndrome, gout, and rheumatoid arthritis. Here, we review the current understanding of the mechanisms underlying inflammation in obesity, T2D, and related disorders. We discuss how chronic tissue inflammation results in IR, impaired insulin secretion, glucose intolerance, and T2D and review the effect of inflammation on diabetic complications and on the relationship between T2D and other pathologies. In this context, we discuss current therapeutic options for the treatment of metabolic disease, advances in the clinic and the potential of immune-modulatory approaches.
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- 2022
75. A 9-Month-Old Boy With “3 Months of Croup” a Devil Inside
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Sah, Amit, Civelli, Valerie F, Donath, Christina, Mandviwala, Lulua, and Heidari, Arash
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Biomedical and Clinical Sciences ,Clinical Sciences ,Clinical Research ,Emerging Infectious Diseases ,Infectious Diseases ,Pediatric ,Child ,Coccidioidomycosis ,Croup ,Humans ,Infant ,Male ,Meningitis ,Mexico ,laryngotracheobronchitis ,croup ,subglottic mass ,coccidioidomycosis ,persistent stridor ,disseminated coccidioidomycosis ,laryngeal coccidioidomycosis ,laryngeal mass ,pediatric croup - Abstract
Coccidioidomycosis (CM) is an endemic fungal disease that is prevalent in the Southwestern United States, Mexico, and Central and South America. The majority of cases are asymptomatic. Symptomatic cases primarily present with pneumonic disease, varying in severity from mild to severe. In a minority, extrapulmonary disease is known to occur. These disseminated cases typically manifest as meningitis, osteomyelitis, synovitis, and integumentary. Coccidioidomycosis has been identified in nearly every part of the body, including the soft tissues and cartilaginous tissues of the oropharynx. Disseminated CM to the larynx specifically in the pediatric populations is rarely documented. This is a case of persistent stridor misdiagnosed as viral croup in a 9-month-old male with protracted disease. Herein, diagnosis and treatment of laryngeal mass found to be CM are defined with a salutatory outcome.
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- 2022
76. Prevalence of Sarcoptes scabiei infestation and its associated factors among primary school children: A school-based cross-sectional survey in the Rufiji district, Tanzania
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Joseph, Mary, Mushi, Vivian, Palilo, Hoseenu, Silvestri, Valeria, Kinabo, Clemence, Mshana, Irene, Chombo, Suleiman, Ndaile, Ismail, and Tarimo, Donath
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- 2024
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77. Early Hyperoxemia and 2-year Outcomes in Infants with Hypoxic-ischemic Encephalopathy: A Secondary Analysis of the Infant Cooling Evaluation Trial
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Badurdeen, Shiraz, Cheong, Jeanie L.Y., Donath, Susan, Graham, Hamish, Hooper, Stuart B., Polglase, Graeme R., Jacobs, Sue, and Davis, Peter G.
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- 2024
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78. Hemostatic radiotherapy in clinically significant tumor-related bleeding: excellent palliative results in a retrospective analysis of 77 patients
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Manuel Guhlich, Teresa Esther Maag, Leif Hendrik Dröge, Andrea Hille, Sandra Donath, Stephanie Bendrich, Markus Anton Schirmer, Friedemann Nauck, Martin Leu, Joachim Riggert, Julia Gallwas, and Stefan Rieken
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Cancer bleeding ,Radiotherapy ,Palliative therapy ,Transfusion ,Retrospective study ,Emergency radiation ,Medical physics. Medical radiology. Nuclear medicine ,R895-920 ,Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Abstract
Abstract Background Significant bleeding of tumor sites is a dreaded complication in oncological diseases and often results in clinical emergencies. Besides basic local and interventional procedures, an urgent radiotherapeutic approach can either achieve a bleeding reduction or a bleeding stop in a vast majority of patients. In spite of being used regularly in clinical practice, data reporting results to this therapy approach is still scarce. Methods We retrospectively analyzed 77 patients treated for significant tumor-related bleeding at our clinic between 2000 and 2021, evaluating treatment response rate, hemoglobin levels, hemoglobin transfusion necessity, administered radiotherapy dose and overall survival. Results Response rate in terms of bleeding stop was 88.3% (68/77) in all patients and 95.2% (60/63) in the subgroup, wherein radiotherapy (RT) was completed as intended. Hemoglobin transfusions decreased during treatment in a further subgroup analysis. Median overall survival (OS) was 3.3 months. Patients with primary tumors (PT) of the cervix (carcinoma of the cervix, CC) or endometrium (endometrioid carcinoma, EDC) and patients receiving the full intended RT dose showed statistically significant better OS in a multivariable cox regression model. Median administered dose was 39 Gy, treatment related acute toxicity was considerably low. Conclusions Our data show an excellent response rate with a low toxicity profile when administering urgent radiotherapy for tumor related clinically significant bleeding complications. Nonetheless, treatment decisions should be highly individual due to the low median overall survival of this patient group.
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- 2023
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79. Agility training to integratively promote neuromuscular, cardiorespiratory and cognitive function in healthy older adults: a one-year randomized-controlled trial
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Eric Lichtenstein, Steffen Held, Ludwig Rappelt, Jonas Zacher, Angi Eibl, Sebastian Ludyga, Oliver Faude, and Lars Donath
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older adults ,agility training ,strength ,balance ,cognition ,multicomponent exercise ,Geriatrics ,RC952-954.6 - Abstract
Abstract Background Exercise training recommendations for seniors include the targeted training of strength, balance, endurance and flexibility domains. Agility training (AT) is conceptualized as a multi-component and time-efficient training framework for older adults to improve physical, functional and cognitive health domains that are relevant for maintaining activities of daily living. The aim of this one-year trial was to comparatively evaluate the effects of agility training on physical and cognitive function. Methods Seventy-nine healthy older adults (AT: 61.5% female, 70.8 ± 4.8 years, 27.7 ± 4.2 kg/m2; CG: 60.5% female, 69.6 ± 4.7 years, 27.5 ± 4.4 kg/m2) took part in this one-year randomized controlled intervention and were either assigned to the agility training group (AT) with two weekly 60 min AT sessions or to the control group (CG), receiving no treatment. Participants were assessed pre, intermediate and post intervention for strength and power, balance, gait speed under multi-task conditions, aerobic capacity as well as cognitive performance. Linear mixed effects models were used to analyze the effect of treatment over time. Results Fifty-four participants (AG: 25, CG: 29) were analyzed, most drop-outs attributed to COVID-19 (17/30 dropouts). Adherence was good (75%) of 90 offered sessions. Notable effects in favor of AT were found for gait parameters in single (d = 0.355, Δ = 4.3%), dual (d = 0.375, Δ = 6.1%) and triple (d = 0.376, Δ = 6.4%) task conditions, counter movement jump performance (strength and power) (d = 0.203, Δ = 6.9%), static one leg balance (d = 0.256, Δ = 12.33%) and n-back reaction time (cognitive performance) (d = 0.204, Δ = 3.8%). No effects were found for the remaining outcomes (d
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- 2023
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80. Intratracheal budesonide mixed with surfactant to increase survival free of bronchopulmonary dysplasia in extremely preterm infants: statistical analysis plan for the international, multicenter, randomized PLUSS trial
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Kate L Francis, Christopher J D McKinlay, C Omar F Kamlin, Jeanie L Y Cheong, Peter A Dargaville, Jennifer A Dawson, Lex W Doyle, Susan E Jacobs, Peter G Davis, Susan M Donath, and Brett J Manley
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Medicine (General) ,R5-920 - Abstract
Abstract Background Bronchopulmonary dysplasia (BPD), an inflammatory-mediated chronic lung disease, is common in extremely preterm infants born before 28 weeks’ gestation and is associated with an increased risk of adverse neurodevelopmental and respiratory outcomes in childhood. Effective and safe prophylactic therapies for BPD are urgently required. Systemic corticosteroids reduce rates of BPD in the short term but are associated with poorer neurodevelopmental outcomes if given to ventilated infants in the first week after birth. Intratracheal administration of corticosteroid admixed with exogenous surfactant could overcome these concerns by minimizing systemic sequelae. Several small, randomized trials have found intratracheal budesonide in a surfactant vehicle to be a promising therapy to increase survival free of BPD. The primary objective of the PLUSS trial is to determine whether intratracheal budesonide mixed with surfactant increases survival free of bronchopulmonary dysplasia (BPD) at 36 weeks’ postmenstrual age (PMA) in extremely preterm infants born before 28 weeks’ gestation. Methods An international, multicenter, double-blinded, randomized trial of intratracheal budesonide (a corticosteroid) mixed with surfactant for extremely preterm infants to increase survival free of BPD at 36 weeks’ postmenstrual age (PMA; primary outcome). Extremely preterm infants aged
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- 2023
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81. Coaches’ Perceptions of Common Planning Concepts Within Training Theory: An International Survey
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Kechi Anyadike-Danes, Lars Donath, and John Kiely
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Periodization ,Resistance training ,Inter-individual response ,Coaches’ perceptions ,Sports medicine ,RC1200-1245 - Abstract
Abstract Background The planning of training is a popular yet controversial topic among coaches and sports scientists. Periodisation is often presented in the literature as the most efficacious approach to planning training. While historically surveys of coaches appeared to support this a key failing was that no unified definition of periodisation exists. Recent surveys offering a periodisation definition and an alternative planning methodology found many choosing the alternative therefore questioning periodisation’s wide acceptance. The current survey looked to explore how coaches perceived specific concepts, drawn from the literature, that relate to the planning of training. Methods 106 coaches [age range: 18–65+ years, 31% 15+ years coaching, 58% individual-events/sports and 32% international level] from across the world completed a novel cross-sectional online survey on the planning of training and the training process. Topics included use of periodisation, division of time into discrete periods, assignment of goals and training to pre-determined periods and the adaptability of pre-established plans. Results The majority described their planning approach as training periodisation (71%). Similarly, there was strong agreement with the necessity to determining a goal for the season (85%) and divide the season into distinct manageable periods of time (73%). When examining whether physical adaptations are achievable within specific and fixed timeframes only a minority (33%) agreed, a similar result was found for training physical capacities in a sequential order (37%). Finally, there was limited support for training targets remaining fixed over a training period (10%). Conclusions As a tool for the planning of athlete’s training, periodisation is often presented as the best and most popular approach. Recent research however has highlighted possible discrepancies in its usage among practitioners. The results of this survey echo this and question the acceptance of periodisation concepts even among periodisation users. In part this may be due to key tenets of periodisation no longer being supported by research or practice. A lingering question then is whether the beliefs of coaches, developed through experience and supported by research, will continue to be marginalized. If sports scientists wish to aid coaches then they need to be engaged in future research initiatives as co-collaborators.
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- 2023
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82. C-reactive protein during pregnancy and in the early postpartum predicts adverse metabolic health outcomes at 1 year postpartum in women with gestational diabetes
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Dan Yedu Quansah, Antje Horsch, Leah Gilbert, Marc Y. Donath, Jardena J. Puder, and the MySweetheart research group
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Gestational diabetes ,C-reactive protein ,Perinatal period ,Metabolic outcomes ,Postpartum ,Body fat ,Diseases of the circulatory (Cardiovascular) system ,RC666-701 - Abstract
Abstract Background Women with gestational diabetes mellitus (GDM) have higher insulin resistance and/or reduced secretion, an increased risk of future diabetes and cardiovascular disease, which may be due to a pathological activation of the innate immune system. C-reactive protein (CRP) is induced by inflammatory cytokines and reflects innate immune activity. We investigated the prospective associations between CRP during the perinatal period with adverse metabolic outcomes at 1 year postpartum in women with previous GDM. Methods We analyzed data from the MySweetheart trial that included 211 women with GDM at 28–32 weeks gestational age (GA). CRP was measured during pregnancy at 28-32 weeks GA, at 6–8 weeks and at 1 year postpartum. Metabolic outcomes at 1 year postpartum included weight, total and central body fat, measures of insulin resistance and secretion and presence of the metabolic syndrome (MetS). A 75 g oral glucose tolerance test was performed to measure glucose and insulin values every 30 min over 2 h to calculate indices of insulin resistance (MATSUDA, HOMA-IR) and of absolute (AUCins/glu, HOMA-B) and insulin resistance-adjusted insulin secretion (ISSI-2). Results CRP during pregnancy and at 6–8 weeks postpartum predicted increased weight, body fat and visceral adipose tissue (VAT), insulin resistance (higher HOMA-IR, lower MATSUDA), absolute insulin secretion (HOMA-B, AUCins/glu), a reduced adjusted insulin secretion (ISSI-2) and a higher prevalence of the MetS at 1 year postpartum (all p ≤ 0.036). These relationships particularly those concerning CRP during pregnancy, were independent of weight ( for VAT, insulin resistance and secretion indices, MetS; all p ≤ 0.032) and of body fat ( for VAT, MATSUDA, MetS; all p ≤ 0.038). Conclusion CRP during pregnancy and in the early postpartum predicted an adverse cardio-metabolic profile in women with prior GDM at 1 year postpartum independent of weight. The prospective association of CRP with increased insulin resistance and reduced adjusted insulin secretion hint to the role of inflammation in the development of impaired metabolism after GDM and could be used as an early marker for risk stratification.
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- 2023
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83. A human antibody against pathologic IAPP aggregates protects beta cells in type 2 diabetes models
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Fabian Wirth, Fabrice D. Heitz, Christine Seeger, Ioana Combaluzier, Karin Breu, Heather C. Denroche, Julien Thevenet, Melania Osto, Paolo Arosio, Julie Kerr-Conte, C. Bruce Verchere, François Pattou, Thomas A. Lutz, Marc Y. Donath, Christoph Hock, Roger M. Nitsch, and Jan Grimm
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Science - Abstract
Abstract In patients with type 2 diabetes, pancreatic beta cells progressively degenerate and gradually lose their ability to produce insulin and regulate blood glucose. Beta cell dysfunction and loss is associated with an accumulation of aggregated forms of islet amyloid polypeptide (IAPP) consisting of soluble prefibrillar IAPP oligomers as well as insoluble IAPP fibrils in pancreatic islets. Here, we describe a human monoclonal antibody selectively targeting IAPP oligomers and neutralizing IAPP aggregate toxicity by preventing membrane disruption and apoptosis in vitro. Antibody treatment in male rats and mice transgenic for human IAPP, and human islet-engrafted mouse models of type 2 diabetes triggers clearance of IAPP oligomers resulting in beta cell protection and improved glucose control. These results provide new evidence for the pathological role of IAPP oligomers and suggest that antibody-mediated removal of IAPP oligomers could be a pharmaceutical strategy to support beta cell function in type 2 diabetes.
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- 2023
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84. Handcycling with concurrent lower body low-frequency electromyostimulation significantly increases acute oxygen uptake in elite wheelchair basketball players: an acute crossover trial
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Ludwig Rappelt, Steffen Held, Florian Micke, Tim Wiedenmann, Jan-Philip Deutsch, Heinz Kleinöder, and Lars Donath
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Cardiorespiratory fitness ,EMS ,Electrical muscle stimulation ,Endurance ,SCI ,Spinal cord injury ,Therapeutics. Pharmacology ,RM1-950 - Abstract
Objective: Wheelchair basketball (WCB) demands high-intensity training due to its intermittent nature. However, acute oxygen uptake (V˙O2) in handcycling is restricted. Combining handcycling with low-frequency electromyostimulation (LF-EMS) may enhance V˙O2 in elite WBC athletes. Design: Randomized crossover trail. Subjects: Twelve German national team WCB players (age: 25.6 [5.6] years, height: 1.75 [0.16] m, mass: 74.0 [21.7] kg, classification: 2.92 [1.26]). Method: Participants underwent 2×5 min of handcycling (60 rpm, ¾ bodyweight resistance in watts) (HANDCYCLE) and 2×5 min of handcycling with concurrent LF-EMS (EMS_HANDCYCLE). LF-EMS (4Hz, 350µs, continuous stimulation) targeted gluteal, quadriceps, and calf muscles, adjusted to individual pain thresholds (buttocks: 69.5 [22.3] mA, thighs: 66.8 [20.0] mA, calves: 68.9 [31.5] mA). Results: Significant mode-dependent differences between HANDCYCLE and EMS_HANDCYCLE were found in V˙O2 (17.60 [3.57] vs 19.23 [4.37] ml min-1 kg-1, p = 0.001) and oxygen pulse (16.69 [4.51] vs 18.41 [5.17] ml, p = 0.002). ΔLactate was significantly lower in HANDCYCLE (0.04 [0.28] vs 0.31 [0.26] mmol l-1). Although perceived effort did not differ (p = 0.293), discomfort was rated lower in HANDCYCLE (1.44 [1.28] vs 3.94 [2.14], p = 0.002). Conclusion: LF-EMS applied to the lower extremities increases oxygen demand during submaximal handcycling. Thus, longitudinal application of LF-EMS should be investigated as a potential training stimulus to improve aerobic capacity in wheelchair athletes.
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- 2024
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85. What helps, what hinders?—Focus group findings on barriers and facilitators for mobile service robot use in a psychosocial group therapy for people with dementia
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Catharina Wasic, Robert Erzgräber, Manja Unger-Büttner, Carolin Donath, Hans-Joachim Böhme, and Elmar Graessel
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dementia ,focus group ,robot-assisted therapy ,institutional care ,user-centered design ,Mechanical engineering and machinery ,TJ1-1570 ,Electronic computers. Computer science ,QA75.5-76.95 - Abstract
IntroductionMany countries are facing a shortage of healthcare workers. Furthermore, healthcare workers are experiencing many stressors, resulting in psychological issues, impaired health, and increased intentions to leave the workplace. In recent years, different technologies have been implemented to lighten workload on healthcare workers, such as electronic patient files. Robotic solutions are still rather uncommon. To help with acceptance and actual use of robots their functionalities should correspond to the users’ needs.MethodIn the pilot study Care4All–Initial, we developed and field-tested applications for a mobile service robot in a psychosocial, multimodal group therapy for people with dementia. To guide the process and assess possible facilitators and barriers, we conducted a reoccurring focus group including people with dementia, therapists, professional caregivers as well as researchers from different disciplines with a user-centered design approach. The focus group suggested and reviewed applications and discussed ethical implications. We recorded the focus group discussions in writing and used content analysis.ResultsThe focus group discussed 15 different topics regarding ethical concerns that we used as a framework for the research project: Ethical facilitators were respect for the autonomy of the people with dementia and their proxies regarding participating and data sharing. Furthermore, the robot had to be useful for the therapists and attendees. Ethical barriers were the deception and possible harm of the people with dementia or therapists. The focus group suggested 32 different applications. We implemented 13 applications that centered on the robot interacting with the people with dementia and lightening the workload off the therapists. The implemented applications were facilitated through utilizing existing hard- and software and building on applications. Barriers to implementation were due to hardware, software, or applications not fitting the scope of the project.DiscussionTo prevent barriers of robot employment in a group therapy for people with dementia, the robot’s applications have to be developed sufficiently for a flawless and safe use, the use of the robot should not cause irritation or agitation, but rather be meaningful and useful to its users. To facilitate the development sufficient time, money, expertise and planning is essential.
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- 2024
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86. Observation of a sudden cessation of a very-high-energy gamma-ray flare in PKS 1510-089 with H.E.S.S. and MAGIC in May 2016
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Collaboration, H. E. S. S., Abdalla, H., Adam, R., Aharonian, F., Benkhali, F. Ait, Angüner, E. O., Arcaro, C., Arm, C., Armstrong, T., Ashkar, H., Backes, M., Baghmanyan, V., Martins, V. Barbosa, Barnacka, A., Barnard, M., Becherini, Y., Berge, D., Bernlöhr, K., Bi, B., Böttcher, M., Boisson, C., Bolmont, J., Bonnefoy, S., de Lavergne, M. de Bony, Bregeon, J., Breuhaus, M., Brun, F., Brun, P., Bryan, M., Büchele, M., Bulik, T., Bylund, T., Caroff, S., Carosi, A., Casanova, S., Ch, T., Ch, S., Chen, A., Cotter, G., Curyło, M., Mbarubucyeye, J. Damascene, Davids, I. D., Davies, J., Deil, C., Devin, J., deWilt, P., Dirson, L., Djannati-Ataï, A., Dmytriiev, A., Donath, A., Doroshenko, V., Dyks, J., Egberts, K., Eichhorn, F., Einecke, S., Emery, G., Ernenwein, J. -P., Feijen, K., Fegan, S., Fiasson, A., de Clairfontaine, G. Fichet, Filipovic, M., Fontaine, G., Funk, S., Füßling, M., Gabici, S., Gallant, Y. A., Giavitto, G., Giunti, L., Glawion, D., Glicenstein, J. F., Gottschall, D., Grondin, M. -H., Hahn, J., Haupt, M., Hermann, G., Hinton, J. A., Hofmann, W., Hoischen, C., Holch, T. L., Holler, M., Hörbe, M., Horns, D., Huber, D., Jamrozy, M., Jankowsky, D., Jankowsky, F., Jardin-Blicq, A., Joshi, V., Jung-Richardt, I., Kastendieck, M. A., Katarzyński, K., Katz, U., Khangulyan, D., Khélifi, B., Klepser, S., Kluźniak, W., Komin, Nu., Konno, R., Kosack, K., Kostunin, D., Kreter, M., Lamanna, G., Lemière, A., Lemoine-Goumard, M., Lenain, J. -P., Levy, C., Lohse, T., Lypova, I., Mackey, J., Majumdar, J., Malyshev, D., Mar, V., Marchegiani, P., Marcowith, A., Mares, A., Martí-Devesa, G., Marx, R., Maurin, G., Meintjes, P. J., Meyer, M., Mitchell, A. M. W., Moderski, R., Mohamed, M., Mohrmann, L., Montanari, A., Moore, C., Morris, P., Moulin, E., Muller, J., Murach, T., Nakashima, K., Nayerhoda, A., de Naurois, M., Ndiyavala, H., Niederwanger, F., Niemiec, J., Oakes, L., O'Brien, P., Odaka, H., Ohm, S., Olivera-Nieto, L., Wilhelmi, E. de Ona, Ostrowski, M., Panter, M., Panny, S., Parsons, R. D., Peron, G., Peyaud, B., Piel, Q., Pita, S., Poireau, V., Noel, A. Priyana, Prokhorov, D. A., Prokoph, H., Pühlhofer, G., Punch, M., Quirrenbach, A., Raab, S., Rauth, R., Reichherzer, P., Reimer, A., Reimer, O., Remy, Q., Renaud, M., Rieger, F., Rinchiuso, L., Romoli, C., Rowell, G., Rudak, B., Ruiz-Velasco, E., Sahakian, V., Sailer, S., Sanchez, D. A., Santangelo, A., Sasaki, M., Scalici, M., Schüssler, F., Schutte, H. M., Schwanke, U., Schwemmer, S., Seglar-Arroyo, M., Senniappan, M., Seyffert, A. S., Shafi, N., Shiningayamwe, K., Simoni, R., Sinha, A., Sol, H., Specovius, A., Spencer, S., Spir-Jacob, M., Stawarz, Ł., Sun, L., Steenkamp, R., Stegmann, C., Steinmassl, S., Steppa, C., Takahashi, T., Tavernier, T., Taylor, A. M., Terrier, R., Tiziani, D., Tluczykont, M., Tomankova, L., Trichard, C., Tsirou, M., Tuffs, R., Uchiyama, Y., van der Walt, D. J., van Eldik, C., van Rensburg, C., van Soelen, B., Vasileiadis, G., Veh, J., Venter, C., Vincent, P., Vink, J., Völk, H. J., Vuillaume, T., Wadiasingh, Z., Wagner, S. J., Watson, J., Werner, F., White, R., Wierzcholska, A., Wong, Yu Wun, Yusafzai, A., Zacharias, M., Zanin, R., Zargaryan, D., Zdziarski, A. A., Zech, A., Zhu, S. J., Zorn, J., Zouari, S., Żywucka, N., Collaboration, MAGIC, Acciari, V. A., Ansoldi, S., Antonelli, L. A., Engels, A. Arbet, Asano, K., Baack, D., Babić, A., Baquero, A., de Almeida, U. Barres, Barrio, J. A., González, J. Becerra, Bednarek, W., Bellizzi, L., Bernardini, E., Berti, A., Besenrieder, J., Bhattacharyya, W., Bigongiari, C., Bil, A., Blanch, O., Bonnoli, G., Bošnjak, Ž., Busetto, G., Carosi, R., Ceribella, G., Cerruti, M., Chai, Y., Chilingarian, A., Cikota, S., Colak, S. M., Colin, U., Colombo, E., Contreras, J. L., Cortina, J., Covino, S., D'Amico, G., D'Elia, V., Da Vela, P., Dazzi, F., De Angelis, A., De Lotto, B., Delfino, M., Delgado, J., Depaoli, D., Di Pierro, F., Di Venere, L., neira, E. Do Souto Espi\, Prester, D. Dominis, Donini, A., Dorner, D., Doro, M., Elsaesser, D., Ramazani, V. Fallah, Fattorini, A., Ferrara, G., Foffano, L., Fonseca, M. V., Font, L., Fruck, C., Fukami, S., López, R. J. García, Garczarczyk, M., Gasparyan, S., Gaug, M., Giglietto, N., Giordano, F., Gliwny, P., Godinović, N., Green, D., Hadasch, D., Hahn, A., Heckmann, L., Herrera, J., Hoang, J., Hrupec, D., Hütten, M., Inada, T., Inoue, S., Ishio, K., Iwamura, Y., Jouvin, L., Kajiwara, Y., Karjalainen, M., Kerszberg, D., Kobayashi, Y., Kubo, H., Kushida, J., Lamastra, A., Lelas, D., Leone, F., Lindfors, E., Lombardi, S., Longo, F., López, M., López-Coto, R., López-Oramas, A., Loporchio, S., Fraga, B. Machado de Oliveira, Maggio, C., Majumdar, P., Makariev, M., Mallamaci, M., Maneva, G., Manganaro, M., Mannheim, K., Maraschi, L., Mariotti, M., Martínez, M., Mazin, D., Mender, S., Mićanović, S., Miceli, D., Miener, T., Minev, M., Mir, J. M., Mirzoyan, R., Molina, E., Moralejo, A., Morcuende, D., Moreno, V., Moretti, E., Munar-Adrover, P., Neustroev, V., Nigro, C., Nilsson, K., Ninci, D., Nishijima, K., Noda, K., Nozaki, S., Ohtani, Y., Oka, T., Otero-Santos, J., Palatiello, M., Paneque, D., Paoletti, R., Paredes, J. M., Pavletić, L., nil, P. Pe\, Perennes, C., Persic, M., Moroni, P. G. Prada, Pr, E., Priyadarshi, C., Puljak, I., Rhode, W., Ribó, M., Rico, J., Righi, C., Rugliancich, A., Saha, L., Sahakyan, N., Saito, T., Sakurai, S., Satalecka, K., Schleicher, B., Schmidt, K., Schweizer, T., Sitarek, J., Šnidarić, I., Sobczynska, D., Spolon, A., Stamerra, A., Strom, D., Strzys, M., Suda, Y., Surić, T., Takahashi, M., Tavecchio, F., Temnikov, P., Terzić, T., Teshima, M., Torres-Albà, N., Tosti, L., Truzzi, S., van Scherpenberg, J., Vanzo, G., Acosta, M. Vazquez, Ventura, S., Verguilov, V., Vigorito, C. F., Vitale, V., Vovk, I., Will, M., Zarić, D., Jorstad, S. G., Marscher, A. P., Boccardi, B., Casadio, C., Hodgson, J., Kim, J. -Y., Krichbaum, T. P., Lähteenmäki, A., Tornikoski, M., Traianou, E., and Weaver, Z. R.
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Astrophysics - High Energy Astrophysical Phenomena ,Astrophysics - Astrophysics of Galaxies - Abstract
The flat spectrum radio quasar (FSRQ) PKS 1510-089 is known for its complex multiwavelength behavior, and is one of only a few FSRQs detected at very high energy (VHE, $E>100\,$GeV) $\gamma$-rays. VHE $\gamma$-ray observations with H.E.S.S. and MAGIC during late May and early June 2016 resulted in the detection of an unprecedented flare, which reveals for the first time VHE $\gamma$-ray intranight variability in this source. While a common variability timescale of $1.5\,$hr is found, there is a significant deviation near the end of the flare with a timescale of $\sim 20\,$min marking the cessation of the event. The peak flux is nearly two orders of magnitude above the low-level emission. For the first time, curvature is detected in the VHE $\gamma$-ray spectrum of PKS 1510-089, which is fully explained through absorption by the extragalactic background light. Optical R-band observations with ATOM reveal a counterpart of the $\gamma$-ray flare, even though the detailed flux evolution differs from the VHE ightcurve. Interestingly, a steep flux decrease is observed at the same time as the cessation of the VHE flare. In the high energy (HE, $E>100\,$MeV) $\gamma$-ray band only a moderate flux increase is observed with Fermi-LAT, while the HE $\gamma$-ray spectrum significantly hardens up to a photon index of 1.6. A search for broad-line region (BLR) absorption features in the $\gamma$-ray spectrum indicates that the emission region is located outside of the BLR. Radio VLBI observations reveal a fast moving knot interacting with a standing jet feature around the time of the flare. As the standing feature is located $\sim 50\,$pc from the black hole, the emission region of the flare may have been located at a significant distance from the black hole. If this correlation is indeed true, VHE $\gamma$ rays have been produced far down the jet where turbulent plasma crosses a standing shock., Comment: 25 pages, 17 figures. Accepted for publication by Astronomy & Astrophysics. Corresponding authors: M. Zacharias, J. Sitarek, D. Sanchez, T. Terzic
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- 2020
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87. Limits on Clustering and Smooth Quintessence from the EFTofLSS
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D'Amico, Guido, Donath, Yaniv, Senatore, Leonardo, and Zhang, Pierre
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Astrophysics - Cosmology and Nongalactic Astrophysics ,High Energy Physics - Phenomenology ,High Energy Physics - Theory - Abstract
We apply the Effective Field Theory of Large-Scale Structure (EFTofLSS) to analyze cosmological models with clustering quintessence, which allows us to consistently describe the parameter region in which the quintessence equation of state $w < - 1$. First, we extend the description of biased tracers in redshift space to the presence of clustering quintessence, and compute the one-loop power spectrum. We solve the EFTofLSS equations using the exact time dependence, which is relevant to obtain unbiased constraints. Then, fitting the full shape of BOSS pre-reconstructed power spectrum measurements, the BOSS post-reconstruction BAO measurements, BAO measurements from 6DF/MGS and eBOSS, the Supernovae from Pantheon, and a prior from BBN, we bound the clustering quintessence equation of state parameter $w=-1.011_{-0.048}^{+0.053}$ at $68\%$ C.L.. Further combining with Planck, we obtain $w=-1.028_{-0.030}^{+0.037}$ at $68\%$ C.L.. We also obtain constraints on smooth quintessence, in the physical regime $w \geq -1$: combining all datasets, we get $-1\leq w < - 0.979$ at $68\%$ C.L.. These results strongly support a cosmological constant., Comment: 41 pages, 10 figures. v2: minor modifications, added references, matches JCAP published version
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- 2020
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88. An extreme particle accelerator in the Galactic plane: HESS J1826$-$130
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Collaboration, H. E. S. S., Abdalla, H., Adam, R., Aharonian, F., Benkhali, F. Ait, Angüner, E. O., Arcaro, C., Armand, C., Armstrong, T., Ashkar, H., Backes, M., Baghmanyan, V., Martins, V. Barbosa, Barnacka, A., Barnard, M., Becherini, Y., Berge, D., Bernlöhr, K., Bi, B., Böttcher, M., Boisson, C., Bolmont, J., de Lavergne, M. de Bony, Bordas, P., Breuhaus, M., Brun, F., Brun, P., Bryan, M., Büchele, M., Bulik, T., Bylund, T., Caroff, S., Carosi, A., Casanova, S., Chand, T., Chandra, S., Chen, A., Cotter, G., Curyło, M., Mbarubucyeye, J. Damascene, Davids, I. D., Davies, J., Deil, C., Devin, J., deWilt, P., Dirson, L., Djannati-Ataï, A., Dmytriiev, A., Donath, A., Doroshenko, V., Duffy, C., Dyks, J., Egberts, K., Eichhorn, F., Einecke, S., Emery, G., Ernenwein, J. -P., Feijen, K., Fegan, S., Fiasson, A., de Clairfontaine, G. Fichet, Fontaine, G., Funk, S., Füßling, M., Gabici, S., Gallant, Y. A., Giavitto, G., Giunti, L., Glawion, D., Glicenstein, J. F., Gottschall, D., Grondin, M. -H., Hahn, J., Haupt, M., Hermann, G., Hinton, J. A., Hofmann, W., Hoischen, C., Holch, T. L., Holler, M., Hörbe, M., Horns, D., Huber, D., Jamrozy, M., Jankowsky, D., Jankowsky, F., Jardin-Blicq, A., Joshi, V., Jung-Richardt, I., Kasai, E., Kastendieck, M. A., Katarzyński, K., Katz, U., Khangulyan, D., Khélifi, B., Klepser, S., Kluźniak, W., Komin, Nu., Konno, R., Kosack, K., Kostunin, D., Kreter, M., Lamanna, G., Lemière, A., Lemoine-Goumard, M., Lenain, J. -P., Levy, C., Lohse, T., Lypova, I., Mackey, J., Majumdar, J., Malyshev, D., Marandon, V., Marchegiani, P., Marcowith, A., Mares, A., Martí-Devesa, G., Marx, R., Maurin, G., Meintjes, P. J., Meyer, M., Mitchell, A., Moderski, R., Mohamed, M., Mohrmann, L., Montanari, A., Moore, C., Morris, P., Moulin, E., Muller, J., Murach, T., Nakashima, K., Nayerhoda, A., de Naurois, M., Ndiyavala, H., Niederwanger, F., Niemiec, J., Oakes, L., O'Brien, P., Odaka, H., Ohm, S., Olivera-Nieto, L., Wilhelmi, E. de Ona, Ostrowski, M., Oya, I., Panter, M., Panny, S., Parsons, R. D., Peron, G., Peyaud, B., Piel, Q., Pita, S., Poireau, V., Noel, A. Priyana, Prokhorov, D. A., Prokoph, H., Pühlhofer, G., Punch, M., Quirrenbach, A., Raab, S., Rauth, R., Reichherzer, P., Reimer, A., Reimer, O., Remy, Q., Renaud, M., Rieger, F., Rinchiuso, L., Romoli, C., Rowell, G., Rudak, B., Ruiz-Velasco, E., Sahakian, V., Sailer, S., Sanchez, D. A., Santangelo, A., Sasaki, M., Scalici, M., Schüssler, F., Schutte, H. M., Schwanke, U., Schwemmer, S., Seglar-Arroyo, M., Senniappan, M., Seyffert, A. S., Shafi, N., Shiningayamwe, K., Simoni, R., Sinha, A., Sol, H., Specovius, A., Spencer, S., Spir-Jacob, M., Stawarz, Ł., Sun, L., Steenkamp, R., Stegmann, C., Steinmassl, S., Steppa, C., Takahashi, T., Tavernier, T., Taylor, A. M., Terrier, R., Tiziani, D., Tluczykont, M., Tomankova, L., Trichard, C., Tsirou, M., Tuffs, R., Uchiyama, Y., van der Walt, D. J., van Eldik, C., van Rensburg, C., van Soelen, B., Vasileiadis, G., Veh, J., Venter, C., Vincent, P., Vink, J., Völk, H. J., Vuillaume, T., Wadiasingh, Z., Wagner, S. J., Watson, J., Werner, F., White, R., Wierzcholska, A., Wong, Yu Wun, Yusafzai, A., Zacharias, M., Zanin, R., Zargaryan, D., Zdziarski, A. A., Zech, A., Zhu, S. J., Ziegler, A., Zorn, J., Zouari, S., and Żywucka, N.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
The unidentified very-high-energy (VHE; E $>$ 0.1 TeV) $\gamma$-ray source, HESS J1826$-$130, was discovered with the High Energy Stereoscopic System (HESS) in the Galactic plane. The analysis of 215 h of HESS data has revealed a steady $\gamma$-ray flux from HESS J1826$-$130, which appears extended with a half-width of 0.21$^{\circ}$ $\pm$ 0.02$^{\circ}_{\text{stat}}$ $\pm$ 0.05$^{\circ}_{\text{sys}}$. The source spectrum is best fit with either a power-law function with a spectral index $\Gamma$ = 1.78 $\pm$ 0.10$_{\text{stat}}$ $\pm$ 0.20$_{\text{sys}}$ and an exponential cut-off at 15.2$^{+5.5}_{-3.2}$ TeV, or a broken power-law with $\Gamma_{1}$ = 1.96 $\pm$ 0.06$_{\text{stat}}$ $\pm$ 0.20$_{\text{sys}}$, $\Gamma_{2}$ = 3.59 $\pm$ 0.69$_{\text{stat}}$ $\pm$ 0.20$_{\text{sys}}$ for energies below and above $E_{\rm{br}}$ = 11.2 $\pm$ 2.7 TeV, respectively. The VHE flux from HESS J1826$-$130 is contaminated by the extended emission of the bright, nearby pulsar wind nebula (PWN), HESS J1825$-$137, particularly at the low end of the energy spectrum. Leptonic scenarios for the origin of HESS J1826$-$130 VHE emission related to PSR J1826$-$1256 are confronted by our spectral and morphological analysis. In a hadronic framework, taking into account the properties of dense gas regions surrounding HESS J1826$-$130, the source spectrum would imply an astrophysical object capable of accelerating the parent particle population up to $\gtrsim$200 TeV. Our results are also discussed in a multiwavelength context, accounting for both the presence of nearby supernova remnants (SNRs), molecular clouds, and counterparts detected in radio, X-rays, and TeV energies., Comment: 9 Pages, 5 Figures
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- 2020
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89. Visualizing the multifractal wavefunctions of a disordered two-dimensional electron gas
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Jäck, Berthold, Zinser, Fabian, onig, Elio J. K\", Wissing, Sune N. P., Schmidt, Anke B., Donath, Markus, Kern, Klaus, and Ast, Christian R.
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Condensed Matter - Mesoscale and Nanoscale Physics ,Condensed Matter - Disordered Systems and Neural Networks - Abstract
The wavefunctions of a disordered two-dimensional electron gas at the quantum-critical Anderson transition are predicted to exhibit multifractal scaling in their real space amplitude. We experimentally investigate the appearance of these characteristics in the spatially resolved local density of states of a two-dimensional mixed surface alloy Bi_xPb_{1-x}/Ag(111), by combining high-resolution scanning tunneling microscopy with spin and angle-resolved inverse-photoemission experiments. Our detailed knowledge of the surface alloy electronic band structure, the exact lattice structure and the atomically resolved local density of states enables us to construct a realistic Anderson tight binding model of the mixed surface alloy, and to directly compare the measured local density of states characteristics with those from our model calculations. The statistical analyses of these two-dimensional local density of states maps reveal their log-normal distributions and multifractal scaling characteristics of the underlying wavefunctions with a finite anomalous scaling exponent. Finally, our experimental results confirm theoretical predictions of an exact scaling symmetry for Anderson quantum phase transitions in the Wigner-Dyson classes., Comment: 10 pages, 7 figures
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- 2020
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90. Search for dark matter signals towards a selection of recently-detected DES dwarf galaxy satellites of the Milky Way with H.E.S.S
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Collaboration, H. E. S. S., Abdallah, H., Adam, R., Aharonian, F., Benkhali, F. Ait, Angüner, E. O., Arakawa, M., Arcaro, C., Armand, C., Armstrong, T., Ashkar, H., Backes, M., Baghmanyan, V., Martins, V. Barbosa, Barnacka, A., Barnard, M., Becherini, Y., Berge, D., Bernlöhr, K., Böttcher, M., Boisson, C., Bolmont, J., Bonnefoy, S., Breuhaus, M., Bregeon, J., Brun, F., Brun, P., Bryan, M., Büchele, M., Bulik, T., Bylund, T., Caroff, S., Carosi, A., Casanova, S., Chand, T., Chandra, S., Chen, A., Cotter, G., Curyło, M., Davids, I. D., Davies, J., Deil, C., Devin, J., deWilt, P., Dirson, L., Djannati-Ataï, A., Dmytriiev, A., Donath, A., Doroshenko, V., Dyks, J., Egberts, K., Eichhorn, F., Emery, G., Ernenwein, J. -P., Eschbach, S., Feijen, K., Fegan, S., Fiasson, A., Fontaine, G., Funk, S., Füßling, M., Gabici, S., Gallant, Y. A., Giavitto, G., Giunti, L., Glawion, D., Glicenstein, J. F., Gottschall, D., Grondin, M. -H., Hahn, J., Haupt, M., Hermann, G., Hinton, J. A., Hofmann, W., Hoischen, C., Holch, T. L., Holler, M., Hörbe, M., Horns, D., Huber, D., Iwasaki, H., Jamrozy, M., Jankowsky, D., Jankowsky, F., Jardin-Blicq, A., Joshi, V., Jung-Richardt, I., Kastendieck, M. A., Katarzyński, K., Katsuragawa, M., Katz, U., Khangulyan, D., Khélifi, B., Klepser, S., Kluźniak, W., Komin, Nu., Konno, R., Kosack, K., Kostunin, D., Kreter, M., Lamanna, G., Lemière, A., Lemoine-Goumard, M., Lenain, J. -P., Leser, E., Levy, C., Lohse, T., Lypova, I., Mackey, J., Majumdar, J., Malyshev, D., Marandon, V., Marchegiani, P., Marcowith, A., Mares, A., Martì-Devesa, G., Marx, R., Maurin, G., Meintjes, P. J., Moderski, R., Mohamed, M., Mohrmann, L., Moore, C., Morris, P., Moulin, E., Muller, J., Murach, T., Nakashima, K., Nakashima, S., de Naurois, M., Ndiyavala, H., Niederwanger, F., Niemiec, J., Oakes, L., O'Brien, P., Odaka, H., Ohm, S., Wilhelmi, E. de Ona, Ostrowski, M., Panter, M., Parsons, R. D., Peyaud, B., Piel, Q., Pita, S., Poireau, V., Noel, A. Priyana, Prokhorov, D. A., Prokoph, H., Pühlhofer, G., Punch, M., Quirrenbach, A., Raab, S., Rauth, R., Reimer, A., Reimer, O., Remy, Q., Renaud, M., Rieger, F., Rinchiuso, L., Romoli, C., Rowell, G., Rudak, B., Ruiz-Velasco, E., Sahakian, V., Sailer, S., Saito, S., Sanchez, D. A., Santangelo, A., Sasaki, M., Scalici, M., Schüssler, F., Schutter, H. M., Schwanke, U., Schwemmer, S., Seglar-Arroyo, M., Senniappan, M., Seyffert, A. S., Shafi, N., Shiningayamwe, K., Simoni, R., Sinha, A., Sol, H., Specovius, A., Spencer, S., Spir-Jacob, M., Stawarz, Ł., Steenkamp, R., Stegmann, C., Steppa, C., Takahashi, T., Tavernier, T., Taylor, A. M., Terrier, R., Tiziani, D., Tluczykont, M., Tomankova, L., Trichard, C., Tsirou, M., Tsuji, N., Tuffs, R., Uchiyama, Y., van der Walt, D. J., van Eldik, C., van Rensburg, C., van Soelen, B., Vasileiadis, G., Veh, J., Venter, C., Viana, A., Vincent, P., Vink, J., Völk, H. J., Vuillaume, T., Wadiasingh, Z., Wagner, S. J., Watson, J., Werner, F., White, R., Wierzcholska, A., Yang, R., Yoneda, H., Zacharias, M., Zanin, R., Zargaryan, D., Zdziarski, A. A., Zech, A., Zhu, S., Zorn, J., and Żywucka, N.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
Dwarf spheroidal galaxy satellites of the Milky Way are prime targets for indirect detection of dark matter with gamma rays due to their proximity, high dark matter content and absence of non-thermal emission processes. Recently, the Dark Energy Survey (DES) revealed the existence of new ultra-faint dwarf spheroidal galaxies in the southern-hemisphere sky, therefore ideally located for ground-based observations with the imaging atmospheric Cherenkov telescope array H.E.S.S. We present a search for very-high-energy ($E\gtrsim100$ GeV) gamma-ray emission using H.E.S.S. observations carried out recently towards Reticulum II, Tucana II, Tucana III, Tucana IV and Grus II satellites. No significant very-high-energy gamma-ray excess is found from the observations on any individual object nor in the combined analysis of all the datasets. Using the most recent modeling of the dark matter distribution in the dwarf galaxy halo, we compute for the first time on DES satellites individual and combined constraints from Cherenkov telescope observations on the annihilation cross section of dark matter particles in the form of Weakly Interacting Massive Particles. The combined 95% C.L. observed upper limits reach $\langle \sigma v \rangle \simeq 1 \times 10^{-23}$ cm$^3$s$^{-1}$ in the $W^+W^-$ channel and $4 \times 10^{-26}$ cm$^3$s$^{-1}$ in the $\gamma\gamma$ channels for a dark matter mass of 1.5 TeV. The H.E.S.S. constraints well complement the results from Fermi-LAT, HAWC, MAGIC and VERITAS and are currently the most stringent in the $\gamma\gamma$ channels in the multi-GeV/multi-TeV mass range., Comment: 20 pages, 12 figures
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- 2020
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91. Resolving acceleration to very high energies along the Jet of Centaurus A
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Collaboration, The H. E. S. S., Abdalla, H., Adam, R., Aharonian, F., Benkhali, F. Ait, Angüner, E. O., Arakawa, M., Arcaro, C., Armand, C., Ashkar, H., Backes, M., Martins, V. Barbosa, Barnard, M., Becherini, Y., Berge, D., Bernlöhr, K., Blackwell, R., Böttcher, M., Boisson, C., Bolmont, J., Bonnefoy, S., Bregeon, J., Breuhaus, M., Brun, F., Brun, P., Bryan, M., Büchele, M., Bulik, T., Bylund, T., Capasso, M., Caroff, S., Carosi, A., Casanova, S., Cerruti, M., Chand, T., Chandra, S., Chen, A., Colafrancesco, S., Curyło, M., Davids, I. D., Deil, C., Devin, J., deWilt, P., Dirson, L., Djannati-Ataï, A., Dmytriiev, A., Donath, A., Doroshenko, V., Drury, L. O'C., Dyks, J., Egberts, K., Emery, G., Ernenwein, J. -P., Eschbach, S., Feijen, K., Fegan, S., Fiasson, A., Fontaine, G., Funk, S., Füßling, M., Gabici, S., Gallant, Y. A., Gaté, F., Giavitto, G., Glawion, D., Glicenstein, J. F., Gottschall, D., Grondin, M. -H., Hahn, J., Haupt, M., Heinzelmann, G., Henri, G., Hermann, G., Hinton, J. A., Hofmann, W., Hoischen, C., Holch, T. L., Holler, M., Horns, D., Huber, D., Iwasaki, H., Jamrozy, M., Jankowsky, D., Jankowsky, F., Jardin-Blicq, A., Jung-Richardt, I., Kastendieck, M. A., Katarzyński, K., Katsuragawa, M., Katz, U., Khangulyan, D., Khélifi, B., King, J., Klepser, S., Kluźniak, W., Komin, N., Kosack, K., Kostunin, D., Kraus, M., Lamanna, G., Lau, J., Lemière, A., Lemoine-Goumard, M., Lenain, J. -P., Leser, E., Levy, C., Lohse, T., Lypova, I., Mackey, J., Majumdar, J., Malyshev, D., Marandon, V., Marcowith, A., Mares, A., Mariaud, C., Martí-Devesa, G., Marx, R., Maurin, G., Meintjes, P. J., Mitchell, A. M. W., Moderski, R., Mohamed, M., Mohrmann, L., Moore, C., Moulin, E., Muller, J., Murach, T., Nakashima, S., de Naurois, M., Ndiyavala, H., Niederwanger, F., Niemiec, J., Oakes, L., O'Brien, P., Odaka, H., Ohm, S., Wilhelmi, E. de Ona, Ostrowski, M., Oya, I., Panter, M., Parsons, R. D., Perennes, C., Petrucci, P. -O., Peyaud, B., Piel, Q., Pita, S., Poireau, V., Noel, A. Priyana, Prokhorov, D. A., Prokoph, H., Pühlhofer, G., Punch, M., Quirrenbach, A., Raab, S., Rauth, R., Reimer, A., Reimer, O., Remy, Q., Renaud, M., Rieger, F., Rinchiuso, L., Romoli, C., Rowell, G., Rudak, B., Ruiz-Velasco, E., Sahakian, V., Saito, S., Sanchez, D. A., Santangelo, A., Sasaki, M., Schlickeiser, R., Schüssler, F., Schulz, A., Schutte, H. M., Schwanke, U., Schwemmer, S., Seglar-Arroyo, M., Senniappan, M., Seyffert, A. S., Shafi, N., Shiningayamwe, K., Simoni, R., Sinha, A., Sol, H., Specovius, A., Spir-Jacob, M., Stawarz, Ł., Steenkamp, R., Stegmann, C., Steppa, C., Takahashi, T., Tavernier, T., Taylor, A. M., Terrier, R., Tiziani, D., Tluczykont, M., Trichard, C., Tsirou, M., Tsuji, N., Tuffs, R., Uchiyama, Y., van der Walt, D. J., van Eldik, C., van Rensburg, C., van Soelen, B., Vasileiadis, G., Veh, J., Venter, C., Vincent, P., Vink, J., Voisin, F., Völk, H. J., Vuillaume, T., Wadiasingh, Z., Wagner, S. J., White, R., Wierzcholska, A., Yang, R., Yonedak, H., Zacharias, M., Zanin, R., Zdziarski, A. A., Zech, A., Ziegler, A., Zorn, J., and Żywucka, N.
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Astrophysics - High Energy Astrophysical Phenomena ,Astrophysics - Astrophysics of Galaxies - Abstract
The nearby radio galaxy Centaurus A belongs to a class of Active Galaxies that are very luminous at radio wavelengths. The majority of these galaxies show collimated relativistic outflows known as jets, that extend over hundreds of thousands of parsecs for the most powerful sources. Accretion of matter onto the central super-massive black hole is believed to fuel these jets and power their emission, with the radio emission being related to the synchrotron radiation of relativistic electrons in magnetic fields. The origin of the extended X-ray emission seen in the kiloparsec-scale jets from these sources is still a matter of debate, although Cen A's X-ray emission has been suggested to originate in electron synchrotron processes. The other possible explanation is Inverse Compton (IC) scattering with CMB soft photons. Synchrotron radiation needs ultra-relativistic electrons ($\sim50$ TeV), and given their short cooling times, requires some continuous re-acceleration mechanism to be active. IC scattering, on the other hand, does not require very energetic electrons, but requires jets that stay highly relativistic on large scales ($\geq$1 Mpc) and that remain well-aligned with the line of sight. Some recent evidence disfavours inverse Compton-CMB models, although other evidence seems to be compatible with them. In principle, the detection of extended gamma-ray emission, directly probing the presence of ultra-relativistic electrons, could distinguish between these options, but instruments have hitherto been unable to resolve the relevant structures. At GeV energies there is also an unusual spectral hardening in Cen A, whose explanation is unclear. Here we report observations of Cen A at TeV energies that resolve its large-scale jet. We interpret the data as evidence for the acceleration of ultra-relativistic electrons in the jet, and favour the synchrotron explanation for the X-rays., Comment: 32 pages, 5 figure
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- 2020
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92. Biased Tracers in Redshift Space in the EFTofLSS with exact time dependence
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Donath, Yaniv and Senatore, Leonardo
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Astrophysics - Cosmology and Nongalactic Astrophysics - Abstract
We study the effect of the Einstein - de Sitter (EdS) approximation on the one-loop power spectrum of galaxies in redshift space in the Effective Field Theory of Large-Scale Structure. The dark matter density perturbations and velocity divergence are treated with exact time dependence. Splitting the density perturbation into its different temporal evolutions naturally gives rise to an irreducible basis of biases. While, as in the EdS approximation, at each time this basis spans a seven-dimensional space, this space is a slightly different one, and the difference is captured by a single calculable time- and $\vec k$-dependent function. We then compute the redshift-space galaxy one-loop power spectrum with the EdS approximation ($P^{\text{EdS-approx}}$) and without ($P^{\text{Exact}}$). For the monopole we find $P_{\text{0}}^{\text{Exact}}/P_{\text{0}}^{\text{EdS-approx}}\sim 1.003$ and for the quadrupole $P_{\text{2}}^{\text{Exact}}/P_{\text{2}}^{\text{EdS-approx}}\sim 1.007$ at $z=0.57$, and sharply increasing at lower redshifts. Finally, we show that a substantial fraction of the effect remains even after allowing the bias coefficients to shift within a physically allowed range. This suggests that the EdS approximation can only fit the data to a level of precision that is roughly comparable to the precision of the next generation of cosmological surveys. Furthermore, we find that implementing the exact time dependence formalism is not demanding and is easily applicable to data. Both of these points motivate a direct study of this effect on the cosmological parameters., Comment: 39 pages, 8 figures. v2: minor corrections, JCAP published version
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- 2020
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93. Probing the magnetic field in the GW170817 outflow using H.E.S.S. observations
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Collaboration, H. E. S. S., Abdalla, H., Adam, R., Aharonian, F., Benkhali, F. Ait, Angüner, E. O., Arakawa, M., Arcaro, C., Armand, C., Armstrong, T., Ashkar, H., Backes, M., Baghmanyan, V., Barbosa-Martins, V., Barnacka, A., Barnard, M., Becherini, Y., Berge, D., Bernlöhr, K., Blackwell, R., Böttcher, M., Boisson, C., Bolmont, J., Bonnefoy, S., Bregeon, J., Breuhaus, M., Brun, F., Brun, P., Bryan, M., Büchele, M., Bulik, T., Bylund, T., Caroff, S., Carosi, A., Casanova, S., Cerruti, M., Chand, T., Chandra, S., Chen, A., Cotter, G., Curyło, M., Davids, I. D., Davies, J., Deil, C., Devin, J., deWilt, P., Dirson, L., Djannati-Ataï, A., Dmytriiev, A., Donath, A., Doroshenko, V., Dyks, J., Egberts, K., Eichhorn, F., Emery, G., Ernenwein, J. -P., Eschbach, S., Feijen, K., Fegan, S., Fiasson, A., Fontaine, G., Funk, S., Füßling, M., Gabici, S., Gallant, Y. A., Giavitto, G., Giunti, L., Glawion, D., Glicenstein, J. F., Gottschall, D., Grondin, M. -H., Hahn, J., Haupt, M., Heinzelmann, G., Hermann, G., Hinton, J. A., Hofmann, W., Hoischen, C., Holch, T. L., Holler, M., Hörbe, M., Horns, D., Huber, D., Iwasaki, H., Jamrozy, M., Jankowsky, D., Jankowsky, F., Jardin-Blicq, A., Joshi, V., Jung-Richardt, I., Kastendieck, M. A., Katarzyński, K., Katsuragawa, M., Katz, U., Khangulyan, D., Khélifi, B., Klepser, S., Kluźniak, W., Komin, Nu., Konno, R., Kosack, K., Kostunin, D., Kreter, M., Lamanna, G., Lemière, A., Lemoine-Goumard, M., Lenain, J. -P., Leser, E., Levy, C., Lohse, T., Lypova, I., Mackey, J., Majumdar, J., Malyshev, D., Marandon, V., Marchegiani, P., Marcowith, A., Mares, A., Martí-Devesa, G., Marx, R., Maurin, G., Meintjes, P. J., Moderski, R., Mohamed, M., Mohrmann, L., Moore, C., Morris, P., Moulin, E., Muller, J., Murach, T., Nakashima, S., Nakashima, K., de Naurois, M., Ndiyavala, H., Niederwanger, F., Niemiec, J., Oakes, L., O'Brien, P., Odaka, H., Ohm, S., Wilhelmi, E. de Ona, Ostrowski, M., Panter, M., Parsons, R. D., Peyaud, B., Piel, Q., Pita, S., Poireau, V., Noel, A. Priyana, Prokhorov, D. A., Prokoph, H., Pühlhofer, G., Punch, M., Quirrenbach, A., Raab, S., Rauth, R., Reimer, A., Reimer, O., Remy, Q., Renaud, M., Rieger, F., Rinchiuso, L., Romoli, C., Rowell, G., Rudak, B., Ruiz-Velasco, E., Sahakian, V., Sailer, S., Saito, S., Sanchez, D. A., Santangelo, A., Sasaki, M., Scalici, M., Schlickeiser, R., Schüssler, F., Schulz, A., Schutte, H., Schwanke, U., Schwemmer, S., Seglar-Arroyo, M., Senniappan, M., Seyffert, A. S., Shafi, N., Shiningayamwe, K., Simoni, R., Sinha, A., Sol, H., Specovius, A., Spencer, S., Spir-Jacob, M., Stawarz, Ł., Steenkamp, R., Stegmann, C., Steppa, C., Takahashi, T., Tavernier, T., Taylor, A. M., Terrier, R., Tiziani, D., Tluczykont, M., Tomankova, L., Trichard, C., Tsirou, M., Tsuji, N., Tuffs, R., Uchiyama, Y., van der Walt, D. J., van Eldik, C., van Rensburg, C., van Soelen, B., Vasileiadis, G., Veh, J., Venter, C., Vincent, P., Vink, J., Völk, H. J., Vuillaume, T., Wadiasingh, Z., Wagner, S. J., Watson, J., Werner, F., White, R., Wierzcholska, A., Yang, R., Yoneda, H., Zacharias, M., Zanin, R., Zdziarski, A. A., Zech, A., Zorn, J., Zywucka, N., and Rodrigues, X.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
The detection of the first electromagnetic counterpart to the binary neutron star (BNS) merger remnant GW170817 established the connection between short $\gamma$-ray bursts and BNS mergers. It also confirmed the forging of heavy elements in the ejecta (a so-called kilonova) via the r-process nucleosynthesis. The appearance of non-thermal radio and X-ray emission, as well as the brightening, which lasted more than 100 days, were somewhat unexpected. Current theoretical models attempt to explain this temporal behavior as either originating from a relativistic off-axis jet or a kilonova-like outflow. In either scenario, there is some ambiguity regarding how much energy is transported in the non-thermal electrons versus the magnetic field of the emission region. Combining the VLA (radio) and Chandra (X-ray) measurements with observations in the GeV-TeV domain can help break this ambiguity, almost independently of the assumed origin of the emission. Here we report for the first time on deep H.E.S.S. observations of GW170817 / GRB 170817A between 124 and 272 days after the BNS merger with the full H.E.S.S. array of telescopes, as well as on an updated analysis of the prompt (<5 days) observations with the upgraded H.E.S.S. phase-I telescopes. We discuss implications of the H.E.S.S. measurement for the magnetic field in the context of different source scenarios., Comment: 7 pages, 2 figures, 1 table
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- 2020
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94. Very high energy $\gamma$-ray emission from two blazars of unknown redshift and upper limits on their distance
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Collaboration, H. E. S. S., Abdalla, H., Adam, R., Aharonian, F., Benkhali, F. Ait, Angüner, E. O., Arakawa, M., Arcaro, C., Armand, C., Armstrong, T., Ashkar, H., Backes, M., Baghmanyan, V., Martins, V. Barbosa, Barnacka, A., Barnard, M., Becherini, Y., Berge, D., Bernlöhr, K., Böttcher, M., Boisson, C., Bolmont, J., Bonnefoy, S., Bregeon, J., Breuhaus, M., Brun, F., Brun, P., Bryan, M., Büchele, M., Bulik, T., Bylund, T., Caroff, S., Carosi, A., Casanova, S., Chand, T., Chandra, S., Chen, A., Cotter, G., Curyło, M., Davids, I. D., Davies, J., Deil, C., Devin, J., deWilt, P., Dirson, L., Djannati-Ataï, A., Dmytriiev, A., Donath, A., Doroshenko, V., Dyks, J., Egberts, K., Eichhorn, F., Emery, G., Ernenwein, J. -P., Feijen, K., Fegan, S., Fiasson, A., Fontaine, G., Funk, S., Füßling, M., Gabici, S., Gallant, Y. A., Giavitto, G., Giunti, L., Glawion, D., Glicenstein, J. F., Gottschall, D., Grondin, M. -H., Hahn, J., Haupt, M., Hermann, G., Hinton, J. A., Hofmann, W., Hoischen, C., Holch, T. L., Holler, M., H{\"}orbe, M., Horns, D., Huber, D., Iwasaki, H., Jamrozy, M., Jankowsky, D., Jankowsky, F., Jardin-Blicq, A., Joshi, V., Jung-Richardt, I., Kastendieck, M. A., Katarzynski, K., Katsuragawa, M., Katz, U., Khangulyan, D., Khélifi, B., Klepser, S., Kluzniak, W., Komin, Nu., Konno, R., Kosack, K., Kostunin, D., Kreter, M., Lamanna, G., Lemière, A., Lemoine-Goumard, M., Lenain, J. -P., Leser, E., Levy, C., Lohse, T., Lypova, I., Mackey, J., Majumdar, J., Malyshev, D., Marandon, V., Marchegiani, P., Marcowith, A., Mares, A., Martí-Devesa, G., Marx, R., Maurin, G., Meintjes, P. J., Moderski, R., Mohamed, M., Mohrmann, L., Moore, C., Morris, P., Moulin, E., Muller, J., Murach, T., Nakashima, S., Nakashima, K., de Naurois, M., Ndiyavala, H., Niederwanger, F., Niemiec, J., Oakes, L., O'Brien, P., Odaka, H., Ohm, S., Wilhelmi, E. de Ona, Ostrowski, M., Panter, M., Parsons, R. D., Peyaud, B., Piel, Q., Pita, S., Poireau, V., Noel, A. Priyana, Prokhorov, D. A., Prokoph, H., Pühlhofer, G., Punch, M., Quirrenbach, A., Raab, S., Rauth, R., Reimer, A., Reimer, O., Remy, Q., Renaud, M., Rieger, F., Rinchiuso, L., Romoli, C., Rowell, G., Rudak, B., Ruiz-Velasco, E., Sahakian, V., Sailer, S., Saito, S., Sanchez, D. A., Santangelo, A., Sasaki, M., Scalici, M., Schüssler, F., Schutte, H. M., Schwanke, U., Schwemmer, S., Seglar-Arroyo, M., Senniappan, M., Seyffert, A. S., Shafi, N., Shiningayamwe, K., Simoni, R., Sinha, A., Sol, H., Specovius, A., Spencer, S., Spir-Jacob, M., Stawarz, Ł., Steenkamp, R., Stegmann, C., Steppa, C., Takahashi, T., Tavernier, T., Taylor, A. M., Terrier, R., Tiziani, D., Tluczykont, M., Tomankova, L., Trichard, C., Tsirou, M., Tsuji, N., Tuffs, R., Uchiyama, Y., van der Walt, D. J., van Eldik, C., van Rensburg, C., van Soelen, B., Vasileiadis, G., Veh, J., Venter, C., Vincent, P., Vink, J., Völk, H. J., Vuillaume, T., Wadiasingh, Z., Wagner, S. J., Watson, J., Werner, F., White, R., Wierzcholska, A., Yang, R., Yoneda, H., Zacharias, M., Zanin, R., Zargaryan, D., Zdziarski, A. A., Zech, A., Zhu, S. J., Zorn, J., Żywucka, N., and Cerruti, M.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
We report on the detection of very-high-energy (VHE; $E > 100$ GeV) $\gamma$-ray emission from the BL Lac objects KUV 00311-1938 and PKS 1440-389 with the High Energy Stereoscopic System (H.E.S.S.). H.E.S.S. observations were accompanied or preceded by multi-wavelength observations with Fermi/LAT, XRT and UVOT on board the Swift satellite, and ATOM. Based on an extrapolation of the Fermi/LAT spectrum towards the VHE $\gamma$-ray regime, we deduce a 95% confidence level upper limit on the unknown redshift of KUV 00311-1938 of z < 0.98, and of PKS 1440-389 of z < 0.53. When combined with previous spectroscopy results the redshift of KUV 00311-1938 is constrained to $0.51 \leq z < 0.98$ and for PKS 1440-389 to $0.14 \lessapprox z < 0.53$., Comment: Accepted for publication in MNRAS. 13 pages, 4 figures
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- 2020
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95. Ausdauer und Ausdauertraining im Sport : Anwendungsbereiche, Diagnostik, Trainingsformen, Organisation, Methoden, Anpassungen
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Faude, Oliver, Donath, Lars, Fröhlich, Michael, Section editor, Güllich, Arne, editor, and Krüger, Michael, editor
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- 2023
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96. (Evidenzbasierte) Trainingsprinzipien
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Donath, Lars, Faude, Oliver, Fröhlich, Michael, Section editor, Güllich, Arne, editor, and Krüger, Michael, editor
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- 2023
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97. Accuracy of unilateral and bilateral gait assessment using a mobile gait analysis system at different walking speeds
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Reinhardt, Lars, Schwesig, René, Schulze, Stephan, Donath, Lars, and Kurz, Eduard
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- 2024
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98. Are some people more susceptible to placebos? A systematic review and meta-analysis of inter-individual variability in musculoskeletal pain
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Saueressig, Tobias, Owen, Patrick J., Pedder, Hugo, Kaczorowski, Svenja, Miller, Clint T., Donath, Lars, and Belavý, Daniel L.
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- 2024
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99. SetQuence & SetOmic: Deep set transformers for whole genome and exome tumour analysis
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Jurenaite, Neringa, León-Periñán, Daniel, Donath, Veronika, Torge, Sunna, and Jäkel, René
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- 2024
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100. EIGER2 hybrid-photon-counting X-ray detectors for advanced synchrotron diffraction experiments
- Author
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Tilman Donath, Dubravka Šišak Jung, Max Burian, Valeria Radicci, Pietro Zambon, Andrew N. Fitch, Catherine Dejoie, Bingbing Zhang, Marie Ruat, Michael Hanfland, Cameron M. Kewish, Grant A. van Riessen, Denys Naumenko, Heinz Amenitsch, Gleb Bourenkov, Gerard Bricogne, Ashwin Chari, and Clemens Schulze-Briese
- Subjects
hybrid photon counting ,pixel detector ,silicon ,cadmium telluride ,count rate ,quantum efficiency ,eiger2 ,Nuclear and particle physics. Atomic energy. Radioactivity ,QC770-798 ,Crystallography ,QD901-999 - Abstract
The ability to utilize a hybrid-photon-counting detector to its full potential can significantly influence data quality, data collection speed, as well as development of elaborate data acquisition schemes. This paper facilitates the optimal use of EIGER2 detectors by providing theory and practical advice on (i) the relation between detector design, technical specifications and operating modes, (ii) the use of corrections and calibrations, and (iii) new acquisition features: a double-gating mode, 8-bit readout mode for increasing temporal resolution, and lines region-of-interest readout mode for frame rates up to 98 kHz. Examples of the implementation and application of EIGER2 at several synchrotron sources (ESRF, PETRA III/DESY, ELETTRA, AS/ANSTO) are presented: high accuracy of high-throughput data in serial crystallography using hard X-rays; suppressing higher harmonics of undulator radiation, improving peak shapes, increasing data collection speed in powder X-ray diffraction; faster ptychography scans; and cleaner and faster pump-and-probe experiments.
- Published
- 2023
- Full Text
- View/download PDF
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