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51. Projected sensitivities of the LUX-ZEPLIN experiment to new physics via low-energy electron recoils

Author

Akerib, DS, Al Musalhi, AK, Alsum, SK, Amarasinghe, CS, Ames, A, Anderson, TJ, Angelides, N, Araújo, HM, Armstrong, JE, Arthurs, M, Bai, X, Balajthy, J, Balashov, S, Bang, J, Bargemann, JW, Bauer, D, Baxter, A, Beltrame, P, Bernard, EP, Bernstein, A, Bhatti, A, Biekert, A, Biesiadzinski, TP, Birch, HJ, Blockinger, GM, Bodnia, E, Boxer, B, Brew, CAJ, Brás, P, Burdin, S, Busenitz, JK, Buuck, M, Cabrita, R, Carmona-Benitez, MC, Cascella, M, Chan, C, Chott, NI, Cole, A, Converse, MV, Cottle, A, Cox, G, Creaner, O, Cutter, JE, Dahl, CE, de Viveiros, L, Dobson, JEY, Druszkiewicz, E, Eriksen, SR, Fan, A, Fayer, S, Fearon, NM, Fiorucci, S, Flaecher, H, Fraser, ED, Fruth, T, Gaitskell, RJ, Genovesi, J, Ghag, C, Gibson, E, Gokhale, S, van der Grinten, MGD, Gwilliam, CB, Hall, CR, Hardy, CA, Haselschwardt, SJ, Hertel, SA, Horn, M, Huang, DQ, Ignarra, CM, Jahangir, O, James, RS, Ji, W, Johnson, J, Kaboth, AC, Kamaha, AC, Kamdin, K, Kazkaz, K, Khaitan, D, Khazov, A, Khurana, I, Kodroff, D, Korley, L, Korolkova, EV, Kraus, H, Kravitz, S, Kreczko, L, Krikler, B, Kudryavtsev, VA, Leason, EA, Lee, J, Leonard, DS, Lesko, KT, Levy, C, Li, J, Liao, J, Lindote, A, Linehan, R, Lippincott, WH, Liu, X, and Lopes, MI

Subjects
Nuclear and Plasma Physics, Particle and High Energy Physics, Physical Sciences
Abstract

LUX-ZEPLIN is a dark matter detector expected to obtain world-leading sensitivity to weakly-interacting massive particles interacting via nuclear recoils with a ∼7-tonne xenon target mass. This paper presents sensitivity projections to several low-energy signals of the complementary electron recoil signal type: 1) an effective neutrino magnetic moment, and 2) an effective neutrino millicharge, both for pp-chain solar neutrinos, 3) an axion flux generated by the Sun, 4) axionlike particles forming the Galactic dark matter, 5) hidden photons, 6) mirror dark matter, and 7) leptophilic dark matter. World-leading sensitivities are expected in each case, a result of the large 5.6 t 1000 d exposure and low expected rate of electron-recoil backgrounds in the

Published
2021

54. Enhancing the sensitivity of the LUX-ZEPLIN (LZ) dark matter experiment to low energy signals

Author

Akerib, D. S., Musalhi, A. K. Al, Alsum, S. K., Amarasinghe, C. S., Ames, A., Anderson, T. J., Angelides, N., Araújo, H. M., Armstrong, J. E., Arthurs, M., Bai, X., Balajthy, J., Balashov, S., Bang, J., Bargemann, J. W., Bauer, D., Baxter, A., Beltrame, P., Bernard, E. P., Bernstein, A., Bhatti, A., Biekert, A., Biesiadzinski, T. P., Birch, H. J., Blockinger, G. M., Boxer, B., Brew, C. A. J., Brás, P., Burdin, S., Busenitz, J. K., Buuck, M., Cabrita, R., Carmona-Benitez, M. C., Cascella, M., Chan, C., Chott, N. I., Cole, A., Converse, M. V., Cottle, A., Cox, G., Cutter, J. E., Dahl, C. E., de Viveiros, L., Dobson, J. E. Y., Druszkiewicz, E., Eriksen, S. R., Fan, A., Fayer, S., Fearon, N. M., Fiorucci, S., Flaecher, H., Fraser, E. D., Fruth, T., Gaitskell, R. J., Genovesi, J., Ghag, C., Gibson, E., Gokhale, S., van der Grinten, M. G. D., Gwilliam, C. B., Hall, C. R., Haselschwardt, S. J., Hertel, S. A., Horn, M., Huang, D. Q., Ignarra, C. M., Jahangir, O., James, R. S., Ji, W., Johnson, J., Kaboth, A. C., Kamaha, A. C., Kamdin, K., Kazkaz, K., Khaitan, D., Khazov, A., Khurana, I., Kodroff, D., Korley, L., Korolkova, E. V., Kraus, H., Kravitz, S., Kreczko, L., Krikler, B., Kudryavtsev, V. A., Leason, E. A., Lesko, K. T., Levy, C., Li, J., Liao, J., Lin, J., Lindote, A., Linehan, R., Lippincott, W. H., Liu, X., Lopes, M. I., Asamar, E. Lopez, Paredes, B. López, Lorenzon, W., Luitz, S., Majewski, P. A., Manalaysay, A., Manenti, L., Mannino, R. L., Marangou, N., McCarthy, M. E., McKinsey, D. N., McLaughlin, J., Miller, E. H., Mizrachi, E., Monte, A., Monzani, M. E., Morad, J. A., Mendoza, J. D. Morales, Morrison, E., Mount, B. J., Murphy, A. St. J., Naim, D., Naylor, A., Nedlik, C., Nelson, H. N., Neves, F., Nikoleyczik, J. A., Olcina, I., Oliver-Mallory, K. C., Pal, S., Palladino, K. J., Palmer, J., Parveen, N., Pease, E. K., Penning, B., Pereira, G., Piepke, A., Qie, Y., Reichenbacher, J., Rhyne, C. A., Richards, A., Riffard, Q., Rischbieter, G. R. C., Rosero, R., Rossiter, P., Santone, D., Sazzad, A. B. M. R., Schnee, R. W., Scovell, P. R., Shaw, S., Shutt, T. A., Silk, J. J., Silva, C., Smith, R., Solmaz, M., Solovov, V. N., Sorensen, P., Stancu, I., Stevens, A., Stifter, K., Suerfu, B., Sumner, T. J., Swanson, N., Szydagis, M., Taylor, W. C., Taylor, R., Temples, D. J., Terman, P. A., Tiedt, D. R., Timalsina, M., To, W. H., Tripathi, M., Tronstad, D. R., Turner, W., Utku, U., Vaitkus, A., Wang, B., Wang, J. J., Wang, W., Watson, J. R., Webb, R. C., White, R. G., Whitis, T. J., Williams, M., Wolfs, F. L. H., Woodward, D., Wright, C. J., Xiang, X., Xu, J., Yeh, M., and Zarzhitsky, P.

Subjects
Astrophysics - Instrumentation and Methods for Astrophysics, Physics - Instrumentation and Detectors
Abstract

Two-phase xenon detectors, such as that at the core of the forthcoming LZ dark matter experiment, use photomultiplier tubes to sense the primary (S1) and secondary (S2) scintillation signals resulting from particle interactions in their liquid xenon target. This paper describes a simulation study exploring two techniques to lower the energy threshold of LZ to gain sensitivity to low-mass dark matter and astrophysical neutrinos, which will be applicable to other liquid xenon detectors. The energy threshold is determined by the number of detected S1 photons; typically, these must be recorded in three or more photomultiplier channels to avoid dark count coincidences that mimic real signals. To lower this threshold: a) we take advantage of the double photoelectron emission effect, whereby a single vacuum ultraviolet photon has a $\sim20\%$ probability of ejecting two photoelectrons from a photomultiplier tube photocathode; and b) we drop the requirement of an S1 signal altogether, and use only the ionization signal, which can be detected more efficiently. For both techniques we develop signal and background models for the nominal exposure, and explore accompanying systematic effects, including the dependence on the free electron lifetime in the liquid xenon. When incorporating double photoelectron signals, we predict a factor of $\sim 4$ sensitivity improvement to the dark matter-nucleon scattering cross-section at $2.5$ GeV/c$^2$, and a factor of $\sim1.6$ increase in the solar $^8$B neutrino detection rate. Dropping the S1 requirement may allow sensitivity gains of two orders of magnitude in both cases. Finally, we apply these techniques to even lower masses by taking into account the atomic Migdal effect; this could lower the dark matter particle mass threshold to $80$ MeV/c$^2$., Comment: 14 pages, 6 figures

Published
2021

55. Tropical field stations yield high conservation return on investment

Author

Timothy M. Eppley, Kim E. Reuter, Timothy M. Sefczek, Jen Tinsman, Luca Santini, Selwyn Hoeks, Seheno Andriantsaralaza, Sam Shanee, Anthony Di Fiore, Joanna M. Setchell, Karen B. Strier, Peter A. Abanyam, Aini Hasanah Abd Mutalib, Ekwoge Abwe, Tanvir Ahmed, Marc Ancrenaz, Raphali R. Andriantsimanarilafy, Andie Ang, Filippo Aureli, Louise Barrett, Jacinta C. Beehner, Marcela E. Benítez, Bruna M. Bezerra, Júlio César Bicca‐Marques, Dominique Bikaba, Robert Bitariho, Christophe Boesch, Laura M. Bolt, Ramesh Boonratana, Thomas M. Butynski, Gustavo R. Canale, Susana Carvalho, Colin A. Chapman, Dilip Chetry, Susan M. Cheyne, Marina Cords, Fanny M. Cornejo, Liliana Cortés‐Ortiz, Camille N. Z. Coudrat, Margaret C. Crofoot, Drew T. Cronin, Alvine Dadjo, S. Chrystelle Dakpogan, Emmanuel Danquah, Tim R. B. Davenport, Yvonne A. deJong, Stella de laTorre, Andrea Dempsey, Judeline C. Dimalibot, Rainer Dolch, Giuseppe Donati, Alejandro Estrada, Rassina A. Farassi, Peter J. Fashing, Eduardo Fernandez‐Duque, Maria J. Ferreira da Silva, Julia Fischer, César F. Flores‐Negrón, Barbara Fruth, Terence Fuh Neba, Lief Erikson Gamalo, Jörg U. Ganzhorn, Paul A. Garber, Smitha D. Gnanaolivu, Mary Katherine Gonder, Sery Ernest Gonedelé Bi, Benoit Goossens, Marcelo Gordo, Juan M. Guayasamin, Diana C. Guzmán‐Caro, Andrew R. Halloran, Jessica A. Hartel, Eckhard W. Heymann, Russell A. Hill, Kimberley J. Hockings, Gottfried Hohmann, Naven Hon, Mariano G. Houngbédji, Michael A. Huffman, Rachel A. Ikemeh, Inaoyom Imong, Mitchell T. Irwin, Patrícia Izar, Leandro Jerusalinsky, Gladys Kalema‐Zikusoka, Beth A. Kaplin, Peter M. Kappeler, Stanislaus M. Kivai, Cheryl D. Knott, Intanon Kolasartsanee, Kathelijne Koops, Martin M. Kowalewski, Deo Kujirakwinja, Ajith Kumar, Quyet K. Le, Rebecca J. Lewis, Aung Ko Lin, Andrés Link, Luz I. Loría, Menladi M. Lormie, Edward E. Louis Jr., Ngwe Lwin, Fiona Maisels, Suchinda Malaivijitnond, Lesley Marisa, Gráinne M. McCabe, W. Scott McGraw, Addisu Mekonnen, Pedro G. Méndez‐Carvajal, Tânia Minhós, David M. Montgomery, Citlalli Morelos‐Juárez, Bethan J. Morgan, David Morgan, Amancio Motove Etingüe, Papa Ibnou Ndiaye, K. Anne‐Isola Nekaris, Nga Nguyen, Vincent Nijman, Radar Nishuli, Marilyn A. Norconk, Luciana I. Oklander, Rahayu Oktaviani, Julia Ostner, Emily Otali, Susan E. Perry, Eduardo J. Pinel Ramos, Leila M. Porter, Jill D. Pruetz, Anne E. Pusey, Helder L. Queiroz, Mónica A. Ramírez, Guy Hermas Randriatahina, Hoby Rasoanaivo, Jonah Ratsimbazafy, Joelisoa Ratsirarson, Josia Razafindramanana, Onja H. Razafindratsima, Vernon Reynolds, Rizaldi Rizaldi, Martha M. Robbins, Melissa E. Rodríguez, Marleny Rosales‐Meda, Crickette M. Sanz, Dipto Sarkar, Anne Savage, Amy L. Schreier, Oliver Schülke, Gabriel H. Segniagbeto, Juan Carlos Serio‐Silva, Arif Setiawan, John Seyjagat, Felipe E. Silva, Elizabeth M. Sinclair, Rebecca L. Smith, Denise Spaan, Fiona A. Stewart, Shirley C. Strum, Martin Surbeck, Magdalena S. Svensson, Mauricio Talebi, Luc Roscelin Tédonzong, Bernardo Urbani, João Valsecchi, Natalie Vasey, Erin R. Vogel, Robert B. Wallace, Janette Wallis, Siân Waters, Roman M. Wittig, Richard W. Wrangham, Patricia C. Wright, and Russell A. Mittermeier

Subjects
biodiversity, climate change, conservation funding, field stations, pandemic, primate‐range countries, General. Including nature conservation, geographical distribution, QH1-199.5
Abstract

Abstract Conservation funding is currently limited; cost‐effective conservation solutions are essential. We suggest that the thousands of field stations worldwide can play key roles at the frontline of biodiversity conservation and have high intrinsic value. We assessed field stations’ conservation return on investment and explored the impact of COVID‐19. We surveyed leaders of field stations across tropical regions that host primate research; 157 field stations in 56 countries responded. Respondents reported improved habitat quality and reduced hunting rates at over 80% of field stations and lower operational costs per km2 than protected areas, yet half of those surveyed have less funding now than in 2019. Spatial analyses support field station presence as reducing deforestation. These “earth observatories” provide a high return on investment; we advocate for increased support of field station programs and for governments to support their vital conservation efforts by investing accordingly.

Published
2024
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56. The LUX-ZEPLIN (LZ) radioactivity and cleanliness control programs

Author

Akerib, D. S., Akerlof, C. W., Akimov, D. Yu., Alquahtani, A., Alsum, S. K., Anderson, T. J., Angelides, N., Araújo, H. M., Arbuckle, A., Armstrong, J. E., Arthurs, M., Auyeung, H., Aviles, S., Bai, X., Bailey, A. J., Balajthy, J., Balashov, S., Bang, J., Barry, M. J., Bauer, D., Bauer, P., Baxter, A., Belle, J., Beltrame, P., Bensinger, J., Benson, T., Bernard, E. P., Bernstein, A., Bhatti, A., Biekert, A., Biesiadzinski, T. P., Birch, H. J., Birrittella, B., Boast, K. E., Bolozdynya, A. I., Boulton, E. M., Boxer, B., Bramante, R., Branson, S., Brás, P., Breidenbach, M., Brew, C. A. J., Buckley, J. H., Bugaev, V. V., Bunker, R., Burdin, S., Busenitz, J. K., Cabrita, R., Campbell, J. S., Carels, C., Carlsmith, D. L., Carlson, B., Carmona-Benitez, M. C., Cascella, M., Chan, C., Cherwinka, J. J., Chiller, A. A., Chiller, C., Chott, N. I., Cole, A., Coleman, J., Colling, D., Conley, R. A., Cottle, A., Coughlen, R., Cox, G., Craddock, W. W., Curran, D., Currie, A., Cutter, J. E., da Cunhaw, J. P., Dahl, C. E., Dardin, S., Dasu, S., Davis, J., Davison, T. J. R., de Viveiros, L., Decheine, N., Dobi, A., Dobson, J. E. Y., Druszkiewicz, E., Dushkin, A., Edberg, T. K., Edwards, W. R., Edwards, B. N., Edwards, J., Elnimr, M. M., Emmet, W. T., Eriksen, S. R., Faham, C. H., Fan, A., Fayer, S., Fiorucci, S., Flaecher, H., Florang, I. M. Fogarty, Ford, P., Francis, V. B., Fraser, E. D., Froborg, F., Fruth, T., Gaitskell, R. J., Gantos, N. J., Garcia, D., Gehman, V. M., Gelfand, R., Genovesi, J., Gerhard, R. M., Ghag, C., Gibson, E., Gilchriese, M. G. D., Gokhale, S., Gomber, B., Gonda, T. G., Greenall, A., Greenwood, S., Gregerson, G., van der Grinten, M. G. D., Gwilliam, C. B., Hall, C. R., Hamilton, D., Hans, S., Hanzel, K., Harrington, T., Harrison, A., Harrison, J., Hasselkus, C., Haselschwardt, S. J., Hemer, D., Hertel, S. A., Heise, J., Hillbrand, S., Hitchcock, O., Hjemfelt, C., Hoff, M. D., Holbrook, B., Holtom, E., Hor, J. Y-K., Horn, M., Huang, D. Q., Hurteau, T. W., Ignarra, C. M., Irving, M. N., Jacobsen, R. G., Jahangir, O., Jeffery, S. N., Ji, W., Johnson, M., Johnson, J., Johnson, P., Jones, W. G., Kaboth, A. C., Kamaha, A., Kamdin, K., Kasey, V., Kazkaz, K., Keefner, J., Khaitan, D., Khaleeq, M., Khazov, A., Khromov, A. V., Khurana, I., Kim, Y. D., Kim, W. T., Kocher, C. D., Kodroff, D., Konovalov, A. M., Korley, L., Korolkova, E. V., Koyuncu, M., Kras, J., Kraus, H., Kravitz, S. W., Krebs, H. J., Kreczko, L., Krikler, B., Kudryavtsev, V. A., Kumpan, A. V., Kyre, S., Lambert, A. R., Landerud, B., Larsen, N. A., Laundrie, A., Leason, E. A., Lee, H. S., Lee, J., Lee, C., Lenardo, B. G., Leonard, D. S., Leonard, R., Lesko, K. T., Levy, C., Li, J., Liu, Y., Liao, J., Liao, F. -T., Lin, J., Lindote, A., Linehan, R., Lippincott, W. H., Liu, R., Liu, X., Loniewski, C., Lopes, M. I., Lopez-Asamar, E., Paredes, B. López, Lorenzon, W., Lucero, D., Luitz, S., Lyle, J. M., Lynch, C., Majewski, P. A., Makkinje, J., Malling, D. C., Manalaysay, A., Manenti, L., Mannino, R. L., Marangou, N., Markley, D. J., MarrLaundrie, P., Martin, T. J., Marzioni, M. F., Maupin, C., McConnell, C. T., McKinsey, D. N., McLaughlin, J., Mei, D. -M., Meng, Y., Miller, E. H., Minaker, Z. J., Mizrachi, E., Mock, J., Molash, D., Monte, A., Monzani, M. E., Morad, J. A., Morrison, E., Mount, B. J., Murphy, A. St. J., Naim, D., Naylor, A., Nedlik, C., Nehrkorn, C., Nelson, H. N., Nesbit, J., Neves, F., Nikkel, J. A., Nikoleyczik, J. A., Nilima, A., O'Dell, J., Oh, H., O'Neill, F. G., O'Sullivan, K., Olcina, I., Olevitch, M. A., Oliver-Mallory, K. C., Oxborough, L., Pagac, A., Pagenkopf, D., Pal, S., Palladino, K. J., Palmaccio, V. M., Palmer, J., Pangilinan, M., Parveen, N., Patton, S. J., Pease, E. K., Penning, B. P., Pereira, G., Pereira, C., Peterson, I. B., Piepke, A., Pierson, S., Powell, S., Preece, R. M., Pushkin, K., Qie, Y., Racine, M., Ratcliff, B. N., Reichenbacher, J., Reichhart, L., Rhyne, C. A., Richards, A., Riffard, Q., Rischbieter, G. R. C., Rodrigues, J. P., Rose, H. J., Rosero, R., Rossiter, P., Rucinski, R., Rutherford, G., Saba, J. S., Sabarots, L., Santone, D., Sarychev, M., Sazzad, A. B. M. R., Schnee, R. W., Schubnell, M., Scovell, P. R., Severson, M., Seymour, D., Shaw, S., Shutt, G. W., Shutt, T. A., Silk, J. J., Silva, C., Skarpaas, K., Skulski, W., Smith, A. R., Smith, R. J., Smith, R. E., So, J., Solmaz, M., Solovov, V. N., Sorensen, P., Sosnovtsev, V. V., Stancu, I., Stark, M. R., Stephenson, S., Stern, N., Stevens, A., Stiegler, T. M., Stifter, K., Studley, R., Sumner, T. J., Sundarnath, K., Sutcliffe, P., Swanson, N., Szydagis, M., Tan, M., Taylor, W. C., Taylor, R., Taylor, D. J., Temples, D., Tennyson, B. P., Terman, P. A., Thomas, K. J., Thomson, J. A., Tiedt, D. R., Timalsina, M., To, W. H., Tomás, A., Tope, T. E., Tripathi, M., Tronstad, D. R., Tull, C. E., Turner, W., Tvrznikova, L., Utes, M., Utku, U., Uvarov, S., Va'vra, J., Vacheret, A., Vaitkus, A., Verbus, J. R., Vietanen, T., Voirin, E., Vuosalo, C. O., Walcott, S., Waldron, W. L., Walker, K., Wang, J. J., Wang, R., Wang, L., Wang, W., Wang, Y., Watson, J. R., Migneault, J., Weatherly, S., Webb, R. C., Wei, W. -Z., While, M., White, R. G., White, J. T., White, D. T., Whitis, T. J., Wisniewski, W. J., Wilson, K., Witherell, M. S., Wolfs, F. L. H., Wolfs, J. D., Woodward, D., Worm, S. D., Xiang, X., Xiao, Q., Xu, J., Yeh, M., Yin, J., Young, I., Zhang, C., and Zarzhitsky, P.

Subjects
Physics - Instrumentation and Detectors, High Energy Physics - Experiment
Abstract

LUX-ZEPLIN (LZ) is a second-generation direct dark matter experiment with spin-independent WIMP-nucleon scattering sensitivity above $1.4 \times 10^{-48}$ cm$^{2}$ for a WIMP mass of 40 GeV/c$^{2}$ and a 1000 d exposure. LZ achieves this sensitivity through a combination of a large 5.6 t fiducial volume, active inner and outer veto systems, and radio-pure construction using materials with inherently low radioactivity content. The LZ collaboration performed an extensive radioassay campaign over a period of six years to inform material selection for construction and provide an input to the experimental background model against which any possible signal excess may be evaluated. The campaign and its results are described in this paper. We present assays of dust and radon daughters depositing on the surface of components as well as cleanliness controls necessary to maintain background expectations through detector construction and assembly. Finally, examples from the campaign to highlight fixed contaminant radioassays for the LZ photomultiplier tubes, quality control and quality assurance procedures through fabrication, radon emanation measurements of major sub-systems, and bespoke detector systems to assay scintillator are presented., Comment: 45 pages (79 inc. tables), 7 figures, 9 tables

Published
2020
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57. Genome-wide association reveals host-specific genomic traits in Escherichia coli

Author

Tiwari, Sumeet K., van der Putten, Boas C. L., Fuchs, Thilo M., Vinh, Trung N., Bootsma, Martin, Oldenkamp, Rik, La Ragione, Roberto, Matamoros, Sebastien, Hoa, Ngo T., Berens, Christian, Leng, Joy, Álvarez, Julio, Ferrandis-Vila, Marta, Ritchie, Jenny M., Fruth, Angelika, Schwarz, Stefan, Domínguez, Lucas, Ugarte-Ruiz, María, Bethe, Astrid, Huber, Charlotte, Johanns, Vanessa, Stamm, Ivonne, Wieler, Lothar H., Ewers, Christa, Fivian-Hughes, Amanda, Schmidt, Herbert, Menge, Christian, Semmler, Torsten, and Schultsz, Constance

Published
2023
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60. The Zoonotic Agent Salmonella

Author

Simon, Sandra, Lamparter, Marina C., Pietsch, Michael, Borowiak, Maria, Fruth, Angelika, Rabsch, Wolfgang, Fischer, Jennie, and Sing, Andreas, editor

Published
2023
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62. Dominance style is a key predictor of vocal use and evolution across nonhuman primates.

Author

Kavanagh, Eithne, Street, Sally E, Angwela, Felix O, Bergman, Thore J, Blaszczyk, Maryjka B, Bolt, Laura M, Briseño-Jaramillo, Margarita, Brown, Michelle, Chen-Kraus, Chloe, Clay, Zanna, Coye, Camille, Thompson, Melissa Emery, Estrada, Alejandro, Fichtel, Claudia, Fruth, Barbara, Gamba, Marco, Giacoma, Cristina, Graham, Kirsty E, Green, Samantha, Grueter, Cyril C, Gupta, Shreejata, Gustison, Morgan L, Hagberg, Lindsey, Hedwig, Daniela, Jack, Katharine M, Kappeler, Peter M, King-Bailey, Gillian, Kuběnová, Barbora, Lemasson, Alban, Inglis, David MacGregor, Machanda, Zarin, MacIntosh, Andrew, Majolo, Bonaventura, Marshall, Sophie, Mercier, Stephanie, Micheletta, Jérôme, Muller, Martin, Notman, Hugh, Ouattara, Karim, Ostner, Julia, Pavelka, Mary SM, Peckre, Louise R, Petersdorf, Megan, Quintero, Fredy, Ramos-Fernández, Gabriel, Robbins, Martha M, Salmi, Roberta, Schamberg, Isaac, Schülke, Oliver, Semple, Stuart, Silk, Joan B, Sosa-Lopéz, J Roberto, Torti, Valeria, Valente, Daria, Ventura, Raffaella, van de Waal, Erica, Weyher, Anna H, Wilke, Claudia, Wrangham, Richard, Young, Christopher, Zanoli, Anna, Zuberbühler, Klaus, Lameira, Adriano R, and Slocombe, Katie

Subjects
communication, dominance style, social behaviour, sociality, vocal
Abstract

Animal communication has long been thought to be subject to pressures and constraints associated with social relationships. However, our understanding of how the nature and quality of social relationships relates to the use and evolution of communication is limited by a lack of directly comparable methods across multiple levels of analysis. Here, we analysed observational data from 111 wild groups belonging to 26 non-human primate species, to test how vocal communication relates to dominance style (the strictness with which a dominance hierarchy is enforced, ranging from 'despotic' to 'tolerant'). At the individual-level, we found that dominant individuals who were more tolerant vocalized at a higher rate than their despotic counterparts. This indicates that tolerance within a relationship may place pressure on the dominant partner to communicate more during social interactions. At the species-level, however, despotic species exhibited a larger repertoire of hierarchy-related vocalizations than their tolerant counterparts. Findings suggest primate signals are used and evolve in tandem with the nature of interactions that characterize individuals' social relationships.

Published
2021

63. Discovery of Novel Herpes Simplexviruses in Wild Gorillas, Bonobos, and Chimpanzees Supports Zoonotic Origin of HSV-2

Author

Wertheim, Joel O, Hostager, Reilly, Ryu, Diane, Merkel, Kevin, Angedakin, Samuel, Arandjelovic, Mimi, Ayimisin, Emmanuel Ayuk, Babweteera, Fred, Bessone, Mattia, Brun-Jeffery, Kathryn J, Dieguez, Paula, Eckardt, Winnie, Fruth, Barbara, Herbinger, Ilka, Jones, Sorrel, Kuehl, Hjalmar, Langergraber, Kevin E, Lee, Kevin, Madinda, Nadege F, Metzger, Sonja, Ormsby, Lucy Jayne, Robbins, Martha M, Sommer, Volker, Stoinski, Tara, Wessling, Erin G, Wittig, Roman M, Yuh, Yisa Ginath, Leendertz, Fabian H, and Calvignac-Spencer, Sébastien

Subjects
Biochemistry and Cell Biology, Evolutionary Biology, Genetics, Biological Sciences, Infectious Diseases, Sexually Transmitted Infections, 2.2 Factors relating to the physical environment, 2.1 Biological and endogenous factors, Infection, Good Health and Well Being, Animals, Herpesvirus 2, Human, Hominidae, Humans, Phylogeny, Sequence Analysis, DNA, Simplexvirus, Viral Zoonoses, phylogenetics, zoonosis, herpesvirus, molecular clock, ape, Biochemistry and cell biology, Evolutionary biology
Abstract

Viruses closely related to human pathogens can reveal the origins of human infectious diseases. Human herpes simplexvirus type 1 (HSV-1) and type 2 (HSV-2) are hypothesized to have arisen via host-virus codivergence and cross-species transmission. We report the discovery of novel herpes simplexviruses during a large-scale screening of fecal samples from wild gorillas, bonobos, and chimpanzees. Phylogenetic analysis indicates that, contrary to expectation, simplexviruses from these African apes are all more closely related to HSV-2 than to HSV-1. Molecular clock-based hypothesis testing suggests the divergence between HSV-1 and the African great ape simplexviruses likely represents a codivergence event between humans and gorillas. The simplexviruses infecting African great apes subsequently experienced multiple cross-species transmission events over the past 3 My, the most recent of which occurred between humans and bonobos around 1 Ma. These findings revise our understanding of the origins of human herpes simplexviruses and suggest that HSV-2 is one of the earliest zoonotic pathogens.

Published
2021

64. The mode of expression divergence in Drosophila fat body is infection-specific

Author

Ramirez-Corona, Bryan A, Fruth, Stephanie, Ofoegbu, Oluchi, and Wunderlich, Zeba

Subjects
Biological Sciences, Genetics, Infectious Diseases, Aetiology, 2.1 Biological and endogenous factors, Infection, Animals, Bacterial Infections, Biological Evolution, Drosophila, Drosophila Proteins, Drosophila melanogaster, Fat Body, Gene Expression, Regulatory Sequences, Nucleic Acid, Medical and Health Sciences, Bioinformatics
Abstract

Transcription is controlled by interactions of cis-acting DNA elements with diffusible trans-acting factors. Changes in cis or trans factors can drive expression divergence within and between species, and their relative prevalence can reveal the evolutionary history and pressures that drive expression variation. Previous work delineating the mode of expression divergence in animals has largely used whole-body expression measurements in one condition. Because cis-acting elements often drive expression in a subset of cell types or conditions, these measurements may not capture the complete contribution of cis-acting changes. Here, we quantify the mode of expression divergence in the Drosophila fat body, the primary immune organ, in several conditions, using two geographically distinct lines of D. melanogaster and their F1 hybrids. We measured expression in the absence of infection and in infections with Gram-negative S. marcescens or Gram-positive E. faecalis bacteria, which trigger the two primary signaling pathways in the Drosophila innate immune response. The mode of expression divergence strongly depends on the condition, with trans-acting effects dominating in response to Gram-negative infection and cis-acting effects dominating in Gram-positive and preinfection conditions. Expression divergence in several receptor proteins may underlie the infection-specific trans effects. Before infection, when the fat body has a metabolic role, there are many compensatory effects, changes in cis and trans that counteract each other to maintain expression levels. This work shows that within a single tissue, the mode of expression divergence varies between conditions and suggests that these differences reflect the diverse evolutionary histories of host-pathogen interactions.

Published
2021

66. Projected sensitivities of the LUX-ZEPLIN (LZ) experiment to new physics via low-energy electron recoils

Author

Collaboration, The LZ, Akerib, DS, Musalhi, AK Al, Alsum, SK, Amarasinghe, CS, Ames, A, Anderson, TJ, Angelides, N, Araújo, HM, Armstrong, JE, Arthurs, M, Bai, X, Balajthy, J, Balashov, S, Bang, J, Bargemann, JW, Bauer, D, Baxter, A, Beltrame, P, Bernard, EP, Bernstein, A, Bhatti, A, Biekert, A, Biesiadzinski, TP, Birch, HJ, Blockinger, GM, Bodnia, E, Boxer, B, Brew, CAJ, Brás, P, Burdin, S, Busenitz, JK, Buuck, M, Cabrita, R, Carmona-Benitez, MC, Cascella, M, Chan, C, Chott, NI, Cole, A, Converse, MV, Cottle, A, Cox, G, Creaner, O, Cutter, JE, Dahl, CE, Viveiros, L de, Dobson, JEY, Druszkiewicz, E, Eriksen, SR, Fan, A, Fayer, S, Fearon, NM, Fiorucci, S, Flaecher, H, Fraser, ED, Fruth, T, Gaitskell, RJ, Genovesi, J, Ghag, C, Gibson, E, Gokhale, S, Grinten, MGD van der, Gwilliam, CB, Hall, CR, Hardy, CA, Haselschwardt, SJ, Hertel, SA, Horn, M, Huang, DQ, Ignarra, CM, Jahangir, O, James, RS, Ji, W, Johnson, J, Kaboth, AC, Kamaha, AC, Kamdin, K, Kazkaz, K, Khaitan, D, Khazov, A, Khurana, I, Kodroff, D, Korley, L, Korolkova, EV, Kraus, H, Kravitz, S, Kreczko, L, Krikler, B, Kudryavtsev, VA, Leason, EA, Lee, J, Leonard, DS, Lesko, KT, Levy, C, Li, J, Liao, J, Lindote, A, Linehan, R, Lippincott, WH, and Liu, X

Subjects
hep-ex, astro-ph.CO, hep-ph
Abstract

LUX-ZEPLIN (LZ) is a dark matter detector expected to obtain world-leadingsensitivity to weakly interacting massive particles (WIMPs) interacting vianuclear recoils with a ~7-tonne xenon target mass. This manuscript presentssensitivity projections to several low-energy signals of the complementaryelectron recoil signal type: 1) an effective neutrino magnetic moment and 2) aneffective neutrino millicharge, both for pp-chain solar neutrinos, 3) an axionflux generated by the Sun, 4) axion-like particles forming the galactic darkmatter, 5) hidden photons, 6) mirror dark matter, and 7) leptophilic darkmatter. World-leading sensitivities are expected in each case, a result of thelarge 5.6t 1000d exposure and low expected rate of electron recoil backgroundsin the $

Published
2021

67. Simulations of events for the LUX-ZEPLIN (LZ) dark matter experiment

Author

Akerib, DS, Akerlof, CW, Alqahtani, A, Alsum, SK, Anderson, TJ, Angelides, N, Araújo, HM, Armstrong, JE, Arthurs, M, Bai, X, Balajthy, J, Balashov, S, Bang, J, Bauer, D, Baxter, A, Bensinger, J, Bernard, EP, Bernstein, A, Bhatti, A, Biekert, A, Biesiadzinski, TP, Birch, HJ, Boast, KE, Boxer, B, Brás, P, Buckley, JH, Bugaev, VV, Burdin, S, Busenitz, JK, Cabrita, R, Carels, C, Carlsmith, DL, Carmona-Benitez, MC, Cascella, M, Chan, C, Chott, NI, Cole, A, Cottle, A, Cutter, JE, Dahl, CE, de Viveiros, L, Dobson, JEY, Druszkiewicz, E, Edberg, TK, Eriksen, SR, Fan, A, Fayer, S, Fiorucci, S, Flaecher, H, Fraser, ED, Fruth, T, Gaitskell, RJ, Genovesi, J, Ghag, C, Gibson, E, Gilchriese, MGD, Gokhale, S, van der Grinten, MGD, Hall, CR, Harrison, A, Haselschwardt, SJ, Hertel, SA, Hor, JY-K, Horn, M, Huang, DQ, Ignarra, CM, Jahangir, O, Ji, W, Johnson, J, Kaboth, AC, Kamaha, AC, Kamdin, K, Kazkaz, K, Khaitan, D, Khazov, A, Khurana, I, Kocher, CD, Korley, L, Korolkova, EV, Kras, J, Kraus, H, Kravitz, S, Kreczko, L, Krikler, B, Kudryavtsev, VA, Leason, EA, Lee, J, Leonard, DS, Lesko, KT, Levy, C, Li, J, Liao, J, Liao, F-T, Lin, J, Lindote, A, Linehan, R, Lippincott, WH, Liu, R, Liu, X, and Loniewski, C

Subjects
Nuclear and Plasma Physics, Particle and High Energy Physics, Physical Sciences, physics.ins-det, hep-ex, Astronomical and Space Sciences, Atomic, Molecular, Nuclear, Particle and Plasma Physics, Nuclear & Particles Physics, Astronomical sciences, Particle and high energy physics
Abstract

The LUX-ZEPLIN dark matter search aims to achieve a sensitivity to the WIMP-nucleon spin-independent cross-section down to (1–2)×10−12 pb at a WIMP mass of 40 GeV/c2. This paper describes the simulations framework that, along with radioactivity measurements, was used to support this projection, and also to provide mock data for validating reconstruction and analysis software. Of particular note are the event generators, which allow us to model the background radiation, and the detector response physics used in the production of raw signals, which can be converted into digitized waveforms similar to data from the operational detector. Inclusion of the detector response allows us to process simulated data using the same analysis routines as developed to process the experimental data.

Published
2021

70. Simulations of Events for the LUX-ZEPLIN (LZ) Dark Matter Experiment

Author

Collaboration, The LUX-ZEPLIN, Akerib, D. S., Akerlof, C. W., Alqahtani, A., Alsum, S. K., Anderson, T. J., Angelides, N., Araújo, H. M., Armstrong, J. E., Arthurs, M., Bai, X., Balajthy, J., Balashov, S., Bang, J., Bauer, D., Baxter, A., Bensinger, J., Bernard, E. P., Bernstein, A., Bhatti, A., Biekert, A., Biesiadzinski, T. P., Birch, H. J., Boast, K. E., Boxer, B., Brás, P., Buckley, J. H., Bugaev, V. V., Burdin, S., Busenitz, J. K., Cabrita, R., Carels, C., Carlsmith, D. L., Carmona-Benitez, M. C., Cascella, M., Chan, C., Chott, N. I., Cole, A., Cottle, A., Cutter, J. E., Dahl, C. E., de Viveiros, L., Dobson, J. E. Y., Druszkiewicz, E., Edberg, T. K., Eriksen, S. R., Fan, A., Fayer, S., Fiorucci, S., Flaecher, H., Fraser, E. D., Fruth, T., Gaitskell, R. J., Genovesi, J., Ghag, C., Gibson, E., Gilchriese, M. G. D., Gokhale, S., van der Grinten, M. G. D., Hall, C. R., Harrison, A., Haselschwardt, S. J., Hertel, S. A., Hor, J. Y-K., Horn, M., Huang, D. Q., Ignarra, C. M., Jahangir, O., Ji, W., Johnson, J., Kaboth, A. C., Kamaha, A. C., Kamdin, K., Kazkaz, K., Khaitan, D., Khazov, A., Khurana, I., Kocher, C. D., Korley, L., Korolkova, E. V., Kras, J., Kraus, H., Kravitz, S., Kreczko, L., Krikler, B., Kudryavtsev, V. A., Leason, E. A., Lee, J., Leonard, D. S., Lesko, K. T., Levy, C., Li, J., Liao, J., Liao, F. -T., Lin, J., Lindote, A., Linehan, R., Lippincott, W. H., Liu, R., Liu, X., Loniewski, C., Lopes, M. I., Paredes, B. López, Lorenzon, W., Luitz, S., Lyle, J. M., Majewski, P. A., Manalaysay, A., Manenti, L., Mannino, R. L., Marangou, N., Marzioni, M. F., McKinsey, D. N., McLaughlin, J., Meng, Y., Miller, E. H., Mizrachi, E., Monte, A., Monzani, M. E., Morad, J. A., Morrison, E., Mount, B. J., Murphy, A. St. J., Naim, D., Naylor, A., Nedlik, C., Nehrkorn, C., Nelson, H. N., Neves, F., Nikoleyczik, J. A., Nilima, A., Olcina, I., Oliver-Mallory, K. C., Pal, S., Palladino, K. J., Palmer, J., Parveen, N., Pease, E. K., Penning, B., Pereira, G., Piepke, A., Pushkin, K., Reichenbacher, J., Rhyne, C. A., Richards, A., Riffard, Q., Rischbieter, G. R. C., Rosero, R., Rossiter, P., Rutherford, G., Santone, D., Sazzad, A. B. M. R., Schnee, R. W., Schubnell, M., Scovell, P. R., Seymour, D., Shaw, S., Shutt, T. A., Silk, J. J., Silva, C., Smith, R., Solmaz, M., Solovov, V. N., Sorensen, P., Stancu, I., Stevens, A., Stifter, K., Sumner, T. J., Swanson, N., Szydagis, M., Tan, M., Taylor, W. C., Taylor, R., Temples, D. J., Terman, P. A., Tiedt, D. R., Timalsina, M., Tomás, A., Tripathi, M., Tronstad, D. R., Turner, W., Tvrznikova, L., Utku, U., Vacheret, A., Vaitkus, A., Wang, J. J., Wang, W., Watson, J. R., Webb, R. C., White, R. G., Whitis, T. J., Wolfs, F. L. H., Woodward, D., Xiang, X., Xu, J., Yeh, M., and Zarzhitsky, P.

Subjects
Physics - Instrumentation and Detectors, High Energy Physics - Experiment
Abstract

The LUX-ZEPLIN dark matter search aims to achieve a sensitivity to the WIMP-nucleon spin-independent cross-section down to (1--2)$\times10^{-12}$\,pb at a WIMP mass of 40 GeV/$c^2$. This paper describes the simulations framework that, along with radioactivity measurements, was used to support this projection, and also to provide mock data for validating reconstruction and analysis software. Of particular note are the event generators, which allow us to model the background radiation, and the detector response physics used in the production of raw signals, which can be converted into digitized waveforms similar to data from the operational detector. Inclusion of the detector response allows us to process simulated data using the same analysis routines as developed to process the experimental data., Comment: 24 pages, 19 figures; Corresponding Authors: A. Cottle, V. Kudryavtsev, D. Woodward

Published
2020
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71. Average phenotype but not plasticity in two metabolic hormones covary in wild female bonobos (Pan paniscus)

Author

Ruth Sonnweber, Gottfried Hohmann, Jeroen M. G. Stevens, Tobias Deschner, Barbara Fruth, Anna-Lena Fiedler, Niina O. Nurmi, and Verena Behringer

Subjects
glucocorticoids, cortisol, thyroid hormones, triiodothyronine (T3), reaction norms, non-invasive, Evolution, QH359-425, Ecology, QH540-549.5
Abstract

Each individual is equipped with a distinct genetic disposition and ontogenetic history and experiences environmental conditions in a unique way. As a result, individuals vary in terms of phenotypic differences regarding their responses to internal and external conditions. By modulating hormone secretion, an individual can react to changing conditions, thus maintaining homeostasis. Cortisol and triiodothyronine (T3) are involved in mediating energy homeostasis. The secretion of metabolic hormones enables individuals to respond flexibly to internal and external conditions. However, this flexibility may be constrained by tradeoffs between average hormone levels and the degree of hormonal plasticity and the impact of the HPA axis on T3 secretion and effects. Like many other species, bonobos (Pan paniscus) are confronted with rapid ecological and climatic perturbations, resulting in challenges to energetic homeostasis. Due to their limited genetic diversity, K-strategist and stenoecious species characteristics, they are predicted to have only limited potential for adaptation. Therefore, it is important to quantify individual cortisol and T3 reaction norms and examine their relationship with each other to understand the level of flexibility of metabolic hormone phenotypes. Using a multivariate random slope model, we found that diurnal urinary excretion patterns of cortisol and T3 in wild female bonobos have (i) no relationship between average phenotype and plasticity within the reaction norms of both hormones. (ii) We also found a negative correlation between the intercepts of the two metabolic hormones, but (iii) no relationship between their slopes. (iv) Standard deviations of cortisol and T3 intercepts and slopes between females indicate little variation among females. Our data show that plasticity within and between the two metabolic hormones is not related to overall low or high hormone levels, but there is a linear negative relationship between cortisol and T3 average phenotypes. Thus, individuals with high average cortisol levels, investing in restoring energy depots, have low average T3 levels, reducing energy expenditure, and vice versa. From this we conclude that the plasticity of diurnal hormone excretion is not affected by average metabolic hormone phenotypes. Evaluations of cortisol and T3 plasticity along ecological gradients can enhance our understanding of the adaptive potential of a given species to environmental changes.

Published
2023
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72. Enhancing the sensitivity of the LUX-ZEPLIN (LZ) dark matter experiment to low energy signals

Author

Akerib, DS, Musalhi, AK Al, Alsum, SK, Amarasinghe, CS, Ames, A, Anderson, TJ, Angelides, N, Araújo, HM, Armstrong, JE, Arthurs, M, Bai, X, Balajthy, J, Balashov, S, Bang, J, Bargemann, JW, Bauer, D, Baxter, A, Beltrame, P, Bernard, EP, Bernstein, A, Bhatti, A, Biekert, A, Biesiadzinski, TP, Birch, HJ, Blockinger, GM, Boxer, B, Brew, CAJ, Brás, P, Burdin, S, Busenitz, JK, Buuck, M, Cabrita, R, Carmona-Benitez, MC, Cascella, M, Chan, C, Chott, NI, Cole, A, Converse, MV, Cottle, A, Cox, G, Cutter, JE, Dahl, CE, Viveiros, L de, Dobson, JEY, Druszkiewicz, E, Eriksen, SR, Fan, A, Fayer, S, Fearon, NM, Fiorucci, S, Flaecher, H, Fraser, ED, Fruth, T, Gaitskell, RJ, Genovesi, J, Ghag, C, Gibson, E, Gokhale, S, Grinten, MGD van der, Gwilliam, CB, Hall, CR, Haselschwardt, SJ, Hertel, SA, Horn, M, Huang, DQ, Ignarra, CM, Jahangir, O, James, RS, Ji, W, Johnson, J, Kaboth, AC, Kamaha, AC, Kamdin, K, Kazkaz, K, Khaitan, D, Khazov, A, Khurana, I, Kodroff, D, Korley, L, Korolkova, EV, Kraus, H, Kravitz, S, Kreczko, L, Krikler, B, Kudryavtsev, VA, Leason, EA, Lesko, KT, Levy, C, Li, J, Liao, J, Lin, J, Lindote, A, Linehan, R, Lippincott, WH, Liu, X, Lopes, MI, Asamar, E Lopez, Paredes, B López, Lorenzon, W, and Luitz, S

Subjects
astro-ph.IM, physics.ins-det
Abstract

Two-phase xenon detectors, such as that at the core of the forthcoming LZdark matter experiment, use photomultiplier tubes to sense the primary (S1) andsecondary (S2) scintillation signals resulting from particle interactions intheir liquid xenon target. This paper describes a simulation study exploringtwo techniques to lower the energy threshold of LZ to gain sensitivity tolow-mass dark matter and astrophysical neutrinos, which will be applicable toother liquid xenon detectors. The energy threshold is determined by the numberof detected S1 photons; typically, these must be recorded in three or morephotomultiplier channels to avoid dark count coincidences that mimic realsignals. To lower this threshold: a) we take advantage of the doublephotoelectron emission effect, whereby a single vacuum ultraviolet photon has a$\sim20\%$ probability of ejecting two photoelectrons from a photomultipliertube photocathode; and b) we drop the requirement of an S1 signal altogether,and use only the ionization signal, which can be detected more efficiently. Forboth techniques we develop signal and background models for the nominalexposure, and explore accompanying systematic effects, including the dependenceon the free electron lifetime in the liquid xenon. When incorporating doublephotoelectron signals, we predict a factor of $\sim 4$ sensitivity improvementto the dark matter-nucleon scattering cross-section at $2.5$ GeV/c$^2$, and afactor of $\sim1.6$ increase in the solar $^8$B neutrino detection rate.Dropping the S1 requirement may allow sensitivity gains of two orders ofmagnitude in both cases. Finally, we apply these techniques to even lowermasses by taking into account the atomic Migdal effect; this could lower thedark matter particle mass threshold to $80$ MeV/c$^2$.

Published
2021

73. Projected sensitivity of the LUX-ZEPLIN experiment to the $0\nu\beta\beta$ decay of $^{136}$Xe

Author

Akerib, D. S., Akerlof, C. W., Alqahtani, A., Alsum, S. K., Anderson, T. J., Angelides, N., Araújo, H. M., Armstrong, J. E., Arthurs, M., Bai, X., Balajthy, J., Balashov, S., Bang, J., Baxter, A., Bensinger, J., Bernard, E. P., Bernstein, A., Bhatti, A., Biekert, A., Biesiadzinski, T. P., Birch, H. J., Boast, K. E., Boxer, B., Brás, P., Buckley, J. H., Bugaev, V. V., Burdin, S., Busenitz, J. K., Cabrita, R., Carels, C., Carlsmith, D. L., Benitez, M. C. Carmona, Cascella, M., Chan, C., Chott, N. I., Cole, A., Cottle, A., Cutter, J. E., Dahl, C. E., de Viveiros, L., Dobson, J. E. Y., Druszkiewicz, E., Edberg, T. K., Eriksen, S. R., Fan, A., Fiorucci, S., Flaecher, H., Fraser, E. D., Fruth, T., Gaitskell, R. J., Genovesi, J., Ghag, C., Gibson, E., Gilchriese, M. G. D., Gokhale, S., van der Grinten, M. G. D., Hall, C. R., Harrison, A., Haselschwardt, S. J., Hertel, S. A., Hor, J. YK., Horn, M., Huang, D. Q., Ignarra, C. M., Jahangir, O., Ji, W., Johnson, J., Kaboth, A. C., Kamaha, A. C., Kamdin, K., Kazkaz, K., Khaitan, D., Khazov, A., Khurana, I., Kocher, C. D., Korley, L., Korolkova, E. V., Kras, J., Kraus, H., Kravitz, S., Kreczko, L., Krikler, B., Kudryavtsev, V. A., Leason, E. A., Lee, J., Leonard, D. S., Lesko, K. T., Levy, C., Li, J., Liao, J., Liao, F. T., Lin, J., Lindote, A., Linehan, R., Lippincott, W. H., Liu, R., Liu, X., Loniewski, C., Lopes, M. I., Paredes, B. López, Lorenzon, W., Luitz, S., Lyle, J. M., Majewski, P. A., Manalaysay, A., Manenti, L., Mannino, R. L., Marangou, N., Marzioni, M. F., McKinsey, D. N., McLaughlin, J., Meng, Y., Miller, E. H., Mizrachi, E., Monte, A., Monzani, M. E., Morad, J. A., Morrison, E., Mount, B. J., Murphy, A. St. J., Naim, D., Naylor, A., Nedlik, C., Nehrkorn, C., Nelson, H. N., Neves, F., Nikoleyczik, J. A., Nilima, A., O'Sullivan, K., Olcina, I., Oliver-Mallory, K. C., Pal, S., Palladino, K. J., Palmer, J., Parveen, N., Pease, E. K., Penning, B., Pereira, G., Pushkin, K., Reichenbacher, J., Rhyne, C. A., Riffard, Q., Rischbieter, G. R. C., Rosero, R., Rossiter, P., Rutherford, G., Santone, D., Sazzad, A. B. M. R., Schnee, R. W., Schubnell, M., Seymour, D., Shaw, S., Shutt, T. A., Silk, J. J., Silva, C., Smith, R., Solmaz, M., Solovov, V. N., Sorensen, P., Stancu, I., Stevens, A., Stifter, K., Sumner, T. J., Swanson, N., Szydagis, M., Tan, M., Taylor, W. C., Taylor, R., Temples, D. J., Terman, P. A., Tiedt, D. R., Timalsina, M., Tomás, A., Tripathi, M., Tronstad, D. R., Turner, W., Tvrznikova, L., Utku, U., Vacheret, A., Vaitkus, A., Wang, J. J., Wang, W., Watson, J. R., Webb, R. C., White, R. G., Whitis, T. J., Wolfs, F. L. H., Woodward, D., Xiang, X., Xu, J., Yeh, M., and Zarzhitsky, P.

Subjects
Nuclear Experiment
Abstract

The LUX-ZEPLIN (LZ) experiment will enable a neutrinoless double beta decay search in parallel to the main science goal of discovering dark matter particle interactions. We report the expected LZ sensitivity to $^{136}$Xe neutrinoless double beta decay, taking advantage of the significant ($>$600 kg) $^{136}$Xe mass contained within the active volume of LZ without isotopic enrichment. After 1000 live-days, the median exclusion sensitivity to the half-life of $^{136}$Xe is projected to be 1.06$\times$10$^{26}$ years (90% confidence level), similar to existing constraints. We also report the expected sensitivity of a possible subsequent dedicated exposure using 90% enrichment with $^{136}$Xe at 1.06$\times$10$^{27}$ years., Comment: 13 pages, 7 figures, 2 tables, version 2 changes: additional clarifications requested by referee on Sections II.A, III.C, III.E, III.F and IV.B

Published
2019
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74. The LUX-ZEPLIN (LZ) Experiment

Author

The LZ Collaboration, Akerib, D. S., Akerlof, C. W., Akimov, D. Yu., Alquahtani, A., Alsum, S. K., Anderson, T. J., Angelides, N., Araújo, H. M., Arbuckle, A., Armstrong, J. E., Arthurs, M., Auyeung, H., Bai, X., Bailey, A. J., Balajthy, J., Balashov, S., Bang, J., Barry, M. J., Barthel, J., Bauer, D., Bauer, P., Baxter, A., Belle, J., Beltrame, P., Bensinger, J., Benson, T., Bernard, E. P., Bernstein, A., Bhatti, A., Biekert, A., Biesiadzinski, T. P., Birrittella, B., Boast, K. E., Bolozdynya, A. I., Boulton, E. M., Boxer, B., Bramante, R., Branson, S., Brás, P., Breidenbach, M., Buckley, J. H., Bugaev, V. V., Bunker, R., Burdin, S., Busenitz, J. K., Campbell, J. S., Carels, C., Carlsmith, D. L., Carlson, B., Carmona-Benitez, M. C., Cascella, M., Chan, C., Cherwinka, J. J., Chiller, A. A., Chiller, C., Chott, N. I., Cole, A., Coleman, J., Colling, D., Conley, R. A., Cottle, A., Coughlen, R., Craddock, W. W., Curran, D., Currie, A., Cutter, J. E., da Cunha, J. P., Dahl, C. E., Dardin, S., Dasu, S., Davis, J., Davison, T. J. R., de Viveiros, L., Decheine, N., Dobi, A., Dobson, J. E. Y., Druszkiewicz, E., Dushkin, A., Edberg, T. K., Edwards, W. R., Edwards, B. N., Edwards, J., Elnimr, M. M., Emmet, W. T., Eriksen, S. R., Faham, C. H., Fan, A., Fayer, S., Fiorucci, S., Flaecher, H., Florang, I. M. Fogarty, Ford, P., Francis, V. B., Froborg, F., Fruth, T., Gaitskell, R. J., Gantos, N. J., Garcia, D., Geffre, A., Gehman, V. M., Gelfand, R., Genovesi, J., Gerhard, R. M., Ghag, C., Gibson, E., Gilchriese, M. G. D., Gokhale, S., Gomber, B., Gonda, T. G., Greenall, A., Greenwood, S., Gregerson, G., van der Grinten, M. G. D., Gwilliam, C. B., Hall, C. R., Hamilton, D., Hans, S., Hanzel, K., Harrington, T., Harrison, A., Hasselkus, C., Haselschwardt, S. J., Hemer, D., Hertel, S. A., Heise, J., Hillbrand, S., Hitchcock, O., Hjemfelt, C., Hoff, M. D., Holbrook, B., Holtom, E., Hor, J. Y-K., Horn, M., Huang, D. Q., Hurteau, T. W., Ignarra, C. M., Irving, M. N., Jacobsen, R. G., Jahangir, O., Jeffery, S. N., Ji, W., Johnson, M., Johnson, J., Johnson, P., Jones, W. G., Kaboth, A. C., Kamaha, A., Kamdin, K., Kasey, V., Kazkaz, K., Keefner, J., Khaitan, D., Khaleeq, M., Khazov, A., Khromov, A. V., Khurana, I., Kim, Y. D., Kim, W. T., Kocher, C. D., Konovalov, A. M., Korley, L., Korolkova, E. V., Koyuncu, M., Kras, J., Kraus, H., Kravitz, S. W., Krebs, H. J., Kreczko, L., Krikler, B., Kudryavtsev, V. A., Kumpan, A. V., Kyre, S., Lambert, A. R., Landerud, B., Larsen, N. A., Laundrie, A., Leason, E. A., Lee, H. S., Lee, J., Lee, C., Lenardo, B. G., Leonard, D. S., Leonard, R., Lesko, K. T., Levy, C., Li, J., Liu, Y., Liao, J., Liao, F. -T., Lin, J., Lindote, A., Linehan, R., Lippincott, W. H., Liu, R., Liu, X., Loniewski, C., Lopes, M. I., Paredes, B. López, Lorenzon, W., Lucero, D., Luitz, S., Lyle, J. M., Lynch, C., Majewski, P. A., Makkinje, J., Malling, D. C., Manalaysay, A., Manenti, L., Mannino, R. L., Marangou, N., Markley, D. J., MarrLaundrie, P., Martin, T. J., Marzioni, M. F., Maupin, C., McConnell, C. T., McKinsey, D. N., McLaughlin, J., Mei, D. -M., Meng, Y., Miller, E. H., Minaker, Z. J., Mizrachi, E., Mock, J., Molash, D., Monte, A., Monzani, M. E., Morad, J. A., Morrison, E., Mount, B. J., Murphy, A. St. J., Naim, D., Naylor, A., Nedlik, C., Nehrkorn, C., Nelson, H. N., Nesbit, J., Neves, F., Nikkel, J. A., Nikoleyczik, J. A., Nilima, A., O'Dell, J., Oh, H., O'Neill, F. G., O'Sullivan, K., Olcina, I., Olevitch, M. A., Oliver-Mallory, K. C., Oxborough, L., Pagac, A., Pagenkopf, D., Pal, S., Palladino, K. J., Palmaccio, V. M., Palmer, J., Pangilinan, M., Patton, S. J., Pease, E. K., Penning, B. P., Pereira, G., Pereira, C., Peterson, I. B., Piepke, A., Pierson, S., Powell, S., Preece, R. M., Pushkin, K., Qie, Y., Racine, M., Ratcliff, B. N., Reichenbacher, J., Reichhart, L., Rhyne, C. A., Richards, A., Riffard, Q., Rischbieter, G. R. C., Rodrigues, J. P., Rose, H. J., Rosero, R., Rossiter, P., Rucinski, R., Rutherford, G., Rynders, D., Saba, J. S., Sabarots, L., Santone, D., Sarychev, M., Sazzad, A. B. M. R., Schnee, R. W., Schubnell, M., Scovell, P. R., Severson, M., Seymour, D., Shaw, S., Shutt, G. W., Shutt, T. A., Silk, J. J., Silva, C., Skarpaas, K., Skulski, W., Smith, A. R., Smith, R. J., Smith, R. E., So, J., Solmaz, M., Solovov, V. N., Sorensen, P., Sosnovtsev, V. V., Stancu, I., Stark, M. R., Stephenson, S., Stern, N., Stevens, A., Stiegler, T. M., Stifter, K., Studley, R., Sumner, T. J., Sundarnath, K., Sutcliffe, P., Swanson, N., Szydagis, M., Tan, M., Taylor, W. C., Taylor, R., Taylor, D. J., Temples, D., Tennyson, B. P., Terman, P. A., Thomas, K. J., Thomson, J. A., Tiedt, D. R., Timalsina, M., To, W. H., Tomás, A., Tope, T. E., Tripathi, M., Tronstad, D. R., Tull, C. E., Turner, W., Tvrznikova, L., Utes, M., Utku, U., Uvarov, S., Va'vra, J., Vacheret, A., Vaitkus, A., Verbus, J. R., Vietanen, T., Voirin, E., Vuosalo, C. O., Walcott, S., Waldron, W. L., Walker, K., Wang, J. J., Wang, R., Wang, L., Wang, Y., Watson, J. R., Migneault, J., Weatherly, S., Webb, R. C., Wei, W. -Z., While, M., White, R. G., White, J. T., White, D. T., Whitis, T. J., Wisniewski, W. J., Wilson, K., Witherell, M. S., Wolfs, F. L. H., Wolfs, J. D., Woodward, D., Worm, S. D., Xiang, X., Xiao, Q., Xu, J., Yeh, M., Yin, J., Young, I., and Zhang, C.

Subjects
Physics - Instrumentation and Detectors, Astrophysics - Instrumentation and Methods for Astrophysics, High Energy Physics - Experiment
Abstract

We describe the design and assembly of the LUX-ZEPLIN experiment, a direct detection search for cosmic WIMP dark matter particles. The centerpiece of the experiment is a large liquid xenon time projection chamber sensitive to low energy nuclear recoils. Rejection of backgrounds is enhanced by a Xe skin veto detector and by a liquid scintillator Outer Detector loaded with gadolinium for efficient neutron capture and tagging. LZ is located in the Davis Cavern at the 4850' level of the Sanford Underground Research Facility in Lead, South Dakota, USA. We describe the major subsystems of the experiment and its key design features and requirements.

Published
2019
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76. Measurement of the Gamma Ray Background in the Davis Cavern at the Sanford Underground Research Facility

Author

Akerib, D. S., Akerlof, C. W., Alsum, S. K., Angelides, N., Araújo, H. M., Armstrong, J. E., Arthurs, M., Bai, X., Balajthy, J., Balashov, S., Baxter, A., Bernard, E. P., Biekert, A., Biesiadzinski, T. P., Boast, K. E., Boxer, B., Brás, P., Buckley, J. H., Bugaev, V. V., Burdin, S., Busenitz, J. K., Carels, C., Carlsmith, D. L., Carmona-Benitez, M. C., Cascella, M., Chan, C., Cole, A., Cottle, A., Cutter, J. E., Dahl, C. E., de Viveiros, L., Dobson, J. E. Y., Druszkiewicz, E., Edberg, T. K., Fan, A., Fiorucci, S., Flaecher, H., Fruth, T., Gaitskell, R. J., Genovesi, J., Ghag, C., Gilchriese, M. G. D., Gokhale, S., van der Grinten, M. G. D., Hall, C. R., Hans, S., Harrison, J., Haselschwardt, S. J., Hertel, S. A., Hor, J. Y-K., Horn, M., Huang, D. Q., Ignarra, C. M., Jahangir, O., Ji, W., Johnson, J., Kaboth, A. C., Kamdin, K., Khaitan, D., Khazov, A., Kim, W. T., Kocher, C. D., Korley, L., Korolkova, E. V., Kras, J., Kraus, H., Kravitz, S. W., Kreczko, L., Krikler, B., Kudryavtsev, V. A., Leason, E. A., Lee, J., Leonard, D. S., Lesko, K. T., Levy, C., Li, J., Liao, J., Liao, F. -T., Lin, J., Lindote, A., Linehan, R., Lippincott, W. H., Liu, R., Liu, X., Loniewski, C., Lopes, M. I., Paredes, B. López, Lorenzon, W., Luitz, S., Lyle, J. M., Majewski, P. A., Manalaysay, A., Manenti, L., Mannino, R. L., Marangou, N., Marzioni, M. F., McKinsey, D. N., McLaughlin, J., Meng, Y., Miller, E. H., Monzani, M. E., Morad, J. A., Morrison, E., Mount, B. J., Murphy, A. St. J., Naim, D., Naylor, A., Nedlik, C., Nehrkorn, C., Nelson, H. N., Neves, F., Nikoleyczik, J., Nilima, A., Olcina, I., Oliver-Mallory, K. C., Pal, S., Palladino, K. J., Pease, E. K., Penning, B. P., Pereira, G., Piepke, A., Pushkin, K., Reichenbacher, J., Rhyne, C. A., Riffard, Q., Rischbieter, G. R. C., Rodrigues, J. P., Rosero, R., Rossiter, P., Rutherford, G., Sazzad, A. B. M. R., Schnee, R. W., Schubnell, M., Scovell, P. R., Seymour, D., Shaw, S., Shutt, T. A., Silk, J. J., Silva, C., Solmaz, M., Solovov, V. N., Sorensen, P., Stancu, I., Stevens, A., Stiegler, T. M., Stifter, K., Szydagis, M., Taylor, W. C., Taylor, R., Temples, D., Terman, P. A., Tiedt, D. R., Timalsina, M., Tomás, A, Tripathi, M., Tvrznikova, L., Utku, U., Uvarov, S., Vacheret, A., Wang, J. J., Watson, J. R., Webb, R. C., White, R. G., Whitis, T. J., Wolfs, F. L. H., Woodward, D., and Yin, J.

Subjects
Physics - Instrumentation and Detectors, High Energy Physics - Experiment
Abstract

Deep underground environments are ideal for low background searches due to the attenuation of cosmic rays by passage through the earth. However, they are affected by backgrounds from $\gamma$-rays emitted by $^{40}$K and the $^{238}$U and $^{232}$Th decay chains in the surrounding rock. The LUX-ZEPLIN (LZ) experiment will search for dark matter particle interactions with a liquid xenon TPC located within the Davis campus at the Sanford Underground Research Facility, Lead, South Dakota, at the 4,850-foot level. In order to characterise the cavern background, in-situ $\gamma$-ray measurements were taken with a sodium iodide detector in various locations and with lead shielding. The integral count rates (0--3300~keV) varied from 596~Hz to 1355~Hz for unshielded measurements, corresponding to a total flux in the cavern of $1.9\pm0.4$~$\gamma~$cm$^{-2}$s$^{-1}$. The resulting activity in the walls of the cavern can be characterised as $220\pm60$~Bq/kg of $^{40}$K, $29\pm15$~Bq/kg of $^{238}$U, and $13\pm3$~Bq/kg of $^{232}$Th., Comment: 11 pages, 9 figures

Published
2019
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77. The LUX-ZEPLIN (LZ) radioactivity and cleanliness control programs

Author

Akerib, DS, Akerlof, CW, Akimov, D Yu, Alquahtani, A, Alsum, SK, Anderson, TJ, Angelides, N, Araújo, HM, Arbuckle, A, Armstrong, JE, Arthurs, M, Auyeung, H, Aviles, S, Bai, X, Bailey, AJ, Balajthy, J, Balashov, S, Bang, J, Barry, MJ, Bauer, D, Bauer, P, Baxter, A, Belle, J, Beltrame, P, Bensinger, J, Benson, T, Bernard, EP, Bernstein, A, Bhatti, A, Biekert, A, Biesiadzinski, TP, Birch, HJ, Birrittella, B, Boast, KE, Bolozdynya, AI, Boulton, EM, Boxer, B, Bramante, R, Branson, S, Brás, P, Breidenbach, M, Brew, CAJ, Buckley, JH, Bugaev, VV, Bunker, R, Burdin, S, Busenitz, JK, Cabrita, R, Campbell, JS, Carels, C, Carlsmith, DL, Carlson, B, Carmona-Benitez, MC, Cascella, M, Chan, C, Cherwinka, JJ, Chiller, AA, Chiller, C, Chott, NI, Cole, A, Coleman, J, Colling, D, Conley, RA, Cottle, A, Coughlen, R, Cox, G, Craddock, WW, Curran, D, Currie, A, Cutter, JE, da Cunha, JP, Dahl, CE, Dardin, S, Dasu, S, Davis, J, Davison, TJR, de Viveiros, L, Decheine, N, Dobi, A, Dobson, JEY, Druszkiewicz, E, Dushkin, A, Edberg, TK, Edwards, WR, Edwards, BN, Edwards, J, Elnimr, MM, Emmet, WT, Eriksen, SR, Faham, CH, Fan, A, Fayer, S, Fiorucci, S, Flaecher, H, Florang, IM Fogarty, Ford, P, Francis, VB, Fraser, ED, Froborg, F, and Fruth, T

Subjects
Nuclear and Plasma Physics, Physical Sciences, physics.ins-det, hep-ex, Atomic, Molecular, Nuclear, Particle and Plasma Physics, Quantum Physics, Nuclear & Particles Physics, Astronomical sciences, Atomic, molecular and optical physics, Particle and high energy physics
Abstract

LUX-ZEPLIN (LZ) is a second-generation direct dark matter experiment with spin-independent WIMP-nucleon scattering sensitivity above 1.4×10-48cm2 for a WIMP mass of 40GeV/c2 and a 1000days exposure. LZ achieves this sensitivity through a combination of a large 5.6t fiducial volume, active inner and outer veto systems, and radio-pure construction using materials with inherently low radioactivity content. The LZ collaboration performed an extensive radioassay campaign over a period of six years to inform material selection for construction and provide an input to the experimental background model against which any possible signal excess may be evaluated. The campaign and its results are described in this paper. We present assays of dust and radon daughters depositing on the surface of components as well as cleanliness controls necessary to maintain background expectations through detector construction and assembly. Finally, examples from the campaign to highlight fixed contaminant radioassays for the LZ photomultiplier tubes, quality control and quality assurance procedures through fabrication, radon emanation measurements of major sub-systems, and bespoke detector systems to assay scintillator are presented.

Published
2020

78. The mode of expression divergence in Drosophila fat body is infection-specific

Author

Ramirez-Corona, Bryan A, Fruth, Stephanie M, Ofoegbu, Oluchi, and Wunderlich, Zeba

Abstract

Transcription is controlled by the interactions of cis-acting DNA elements with diffusible trans-acting factors. Changes in cis or trans factors can drive expression divergence within and between species, and the relative prevalence of each can reveal the evolutionary history and pressures that drive expression variation. Previous work delineating the mode of expression divergence in animals has largely used whole body expression measurements in a single condition. Since cis-acting elements often drive expression in a subset of cell types or conditions, these measurements may not capture the complete contribution of cis-acting changes. Here, we quantify the mode of expression divergence in the Drosophila fat body, the primary immune organ, in several conditions. We performed allele-specific expression analysis using two geographically distinct lines of D. melanogaster and their F1 hybrids. We measured expression in the absence of infection and in separate infections with Gram-negative S. marcescens or Gram-positive E. faecalis bacteria, which trigger the two primary signaling pathways in the Drosophila innate immune response. The mode of expression divergence strongly depends on the condition, with trans-acting effects dominating in response to Gram-positive infection and cis-acting effects dominating in Gram-negative and pre-infection conditions. Expression divergence in several receptor proteins may underlie the infection-specific trans effects. Before infection, when the fat body has a metabolic role, there are many compensatory effects, changes in cis and trans that counteract each other to maintain expression levels. This work demonstrates that within a single tissue, the mode of expression divergence varies between conditions and suggests that these differences reflect the diverse evolutionary histories of host-pathogen interactions.

Published
2020

79. Projected sensitivity of the LUX-ZEPLIN experiment to the 0νββ decay of Xe136

Author

Akerib, DS, Akerlof, CW, Alqahtani, A, Alsum, SK, Anderson, TJ, Angelides, N, Araújo, HM, Armstrong, JE, Arthurs, M, Bai, X, Balajthy, J, Balashov, S, Bang, J, Baxter, A, Bensinger, J, Bernard, EP, Bernstein, A, Bhatti, A, Biekert, A, Biesiadzinski, TP, Birch, HJ, Boast, KE, Boxer, B, Brás, P, Buckley, JH, Bugaev, VV, Burdin, S, Busenitz, JK, Cabrita, R, Carels, C, Carlsmith, DL, Carmona-Benitez, MC, Cascella, M, Chan, C, Chott, NI, Cole, A, Cottle, A, Cutter, JE, Dahl, CE, de Viveiros, L, Dobson, JEY, Druszkiewicz, E, Edberg, TK, Eriksen, SR, Fan, A, Fiorucci, S, Flaecher, H, Fraser, ED, Fruth, T, Gaitskell, RJ, Genovesi, J, Ghag, C, Gibson, E, Gilchriese, MGD, Gokhale, S, van der Grinten, MGD, Hall, CR, Harrison, A, Haselschwardt, SJ, Hertel, SA, Hor, JY-K, Horn, M, Huang, DQ, Ignarra, CM, Jahangir, O, Ji, W, Johnson, J, Kaboth, AC, Kamaha, AC, Kamdin, K, Kazkaz, K, Khaitan, D, Khazov, A, Khurana, I, Kocher, CD, Korley, L, Korolkova, EV, Kras, J, Kraus, H, Kravitz, S, Kreczko, L, Krikler, B, Kudryavtsev, VA, Leason, EA, Lee, J, Leonard, DS, Lesko, KT, Levy, C, Li, J, Liao, J, Liao, F-T, Lin, J, Lindote, A, Linehan, R, Lippincott, WH, Liu, R, Liu, X, Loniewski, C, Lopes, MI, and Paredes, B López

Subjects
Nuclear and Plasma Physics, Particle and High Energy Physics, Physical Sciences, nucl-ex, Nuclear and plasma physics
Abstract

The LUX-ZEPLIN (LZ) experiment will enable a neutrinoless double β decay search in parallel to the main science goal of discovering dark matter particle interactions. We report the expected LZ sensitivity to Xe136 neutrinoless double β decay, taking advantage of the significant (>600 kg) Xe136 mass contained within the active volume of LZ without isotopic enrichment. After 1000 live-days, the median exclusion sensitivity to the half-life of Xe136 is projected to be 1.06×1026 years (90% confidence level), similar to existing constraints. We also report the expected sensitivity of a possible subsequent dedicated exposure using 90% enrichment with Xe136 at 1.06×1027 years.

Published
2020

80. Measurement of the gamma ray background in the Davis cavern at the Sanford Underground Research Facility

Author

Akerib, DS, Akerlof, CW, Alsum, SK, Angelides, N, Araújo, HM, Armstrong, JE, Arthurs, M, Bai, X, Balajthy, J, Balashov, S, Baxter, A, Bernard, EP, Biekert, A, Biesiadzinski, TP, Boast, KE, Boxer, B, Brás, P, Buckley, JH, Bugaev, VV, Burdin, S, Busenitz, JK, Carels, C, Carlsmith, DL, Carmona-Benitez, MC, Cascella, M, Chan, C, Cole, A, Cottle, A, Cutter, JE, Dahl, CE, de Viveiros, L, Dobson, JEY, Druszkiewicz, E, Edberg, TK, Fan, A, Fiorucci, S, Flaecher, H, Fruth, T, Gaitskell, RJ, Genovesi, J, Ghag, C, Gilchriese, MGD, Gokhale, S, van der Grinten, MGD, Hall, CR, Hans, S, Harrison, J, Haselschwardt, SJ, Hertel, SA, Hor, JYK, Horn, M, Huang, DQ, Ignarra, CM, Jahangir, O, Ji, W, Johnson, J, Kaboth, AC, Kamdin, K, Khaitan, D, Khazov, A, Kim, WT, Kocher, CD, Korley, L, Korolkova, EV, Kras, J, Kraus, H, Kravitz, SW, Kreczko, L, Krikler, B, Kudryavtsev, VA, Leason, EA, Lee, J, Leonard, DS, Lesko, KT, Levy, C, Li, J, Liao, J, Liao, FT, Lin, J, Lindote, A, Linehan, R, Lippincott, WH, Liu, R, Liu, X, Loniewski, C, Lopes, MI, López Paredes, B, Lorenzon, W, Luitz, S, Lyle, JM, Majewski, PA, Manalaysay, A, Manenti, L, Mannino, RL, Marangou, N, Marzioni, MF, McKinsey, DN, McLaughlin, J, Meng, Y, and Miller, EH

Subjects
Dark matter, Low background, Radiation, Underground, Gamma rays, Gamma spectroscopy, physics.ins-det, hep-ex, Nuclear & Particles Physics, Astronomical and Space Sciences, Atomic, Molecular, Nuclear, Particle and Plasma Physics
Abstract

Deep underground environments are ideal for low background searches due to the attenuation of cosmic rays by passage through the earth. However, they are affected by backgrounds from γ-rays emitted by 40K and the 238U and 232Th decay chains in the surrounding rock. The LUX-ZEPLIN (LZ) experiment will search for dark matter particle interactions with a liquid xenon TPC located within the Davis campus at the Sanford Underground Research Facility, Lead, South Dakota, at the 4850-foot level. In order to characterise the cavern background, in-situ γ-ray measurements were taken with a sodium iodide detector in various locations and with lead shielding. The integral count rates (0–3300 keV) varied from 596 Hz to 1355 Hz for unshielded measurements, corresponding to a total flux from the cavern walls of 1.9 ± 0.4 γ cm−2s−1. The resulting activity in the walls of the cavern can be characterised as 220 ± 60 Bq/kg of 40K, 29 ± 15 Bq/kg of 238U, and 13 ± 3 Bq/kg of 232Th.

Published
2020

81. Projected WIMP sensitivity of the LUX-ZEPLIN dark matter experiment

Author

Akerib, DS, Akerlof, CW, Alsum, SK, Araújo, HM, Arthurs, M, Bai, X, Bailey, AJ, Balajthy, J, Balashov, S, Bauer, D, Belle, J, Beltrame, P, Benson, T, Bernard, EP, Biesiadzinski, TP, Boast, KE, Boxer, B, Brás, P, Buckley, JH, Bugaev, VV, Burdin, S, Busenitz, JK, Carels, C, Carlsmith, DL, Carlson, B, Carmona-Benitez, MC, Chan, C, Cherwinka, JJ, Cole, A, Cottle, A, Craddock, WW, Currie, A, Cutter, JE, Dahl, CE, de Viveiros, L, Dobi, A, Dobson, JEY, Druszkiewicz, E, Edberg, TK, Edwards, WR, Fan, A, Fayer, S, Fiorucci, S, Fruth, T, Gaitskell, RJ, Genovesi, J, Ghag, C, Gilchriese, MGD, van der Grinten, MGD, Hall, CR, Hans, S, Hanzel, K, Haselschwardt, SJ, Hertel, SA, Hillbrand, S, Hjemfelt, C, Hoff, MD, Hor, JY-K, Huang, DQ, Ignarra, CM, Ji, W, Kaboth, AC, Kamdin, K, Keefner, J, Khaitan, D, Khazov, A, Kim, YD, Kocher, CD, Korolkova, EV, Kraus, H, Krebs, HJ, Kreczko, L, Krikler, B, Kudryavtsev, VA, Kyre, S, Lee, J, Lenardo, BG, Leonard, DS, Lesko, KT, Levy, C, Li, J, Liao, J, Liao, F-T, Lin, J, Lindote, A, Linehan, R, Lippincott, WH, Liu, X, Lopes, MI, Paredes, B López, Lorenzon, W, Luitz, S, Lyle, JM, Majewski, P, Manalaysay, A, Mannino, RL, Maupin, C, McKinsey, DN, Meng, Y, and Miller, EH

Subjects
Nuclear and Plasma Physics, Particle and High Energy Physics, Physical Sciences, astro-ph.IM, astro-ph.CO, hep-ex, physics.ins-det
Abstract

LUX-ZEPLIN (LZ) is a next-generation dark matter direct detection experiment that will operate 4850 feet underground at the Sanford Underground Research Facility (SURF) in Lead, South Dakota, USA. Using a two-phase xenon detector with an active mass of 7 tonnes, LZ will search primarily for low-energy interactions with weakly interacting massive particles (WIMPs), which are hypothesized to make up the dark matter in our galactic halo. In this paper, the projected WIMP sensitivity of LZ is presented based on the latest background estimates and simulations of the detector. For a 1000 live day run using a 5.6-tonne fiducial mass, LZ is projected to exclude at 90% confidence level spin-independent WIMP-nucleon cross sections above 1.4×10-48 cm2 for a 40 GeV/c2 mass WIMP. Additionally, a 5σ discovery potential is projected, reaching cross sections below the exclusion limits of recent experiments. For spin-dependent WIMP-neutron(-proton) scattering, a sensitivity of 2.3×10-43 cm2 (7.1×10-42 cm2) for a 40 GeV/c2 mass WIMP is expected. With underground installation well underway, LZ is on track for commissioning at SURF in 2020.

Published
2020

82. The LUX-ZEPLIN (LZ) experiment

Author

Akerib, DS, Akerlof, CW, Akimov, DY, Alquahtani, A, Alsum, SK, Anderson, TJ, Angelides, N, Araújo, HM, Arbuckle, A, Armstrong, JE, Arthurs, M, Auyeung, H, Bai, X, Bailey, AJ, Balajthy, J, Balashov, S, Bang, J, Barry, MJ, Barthel, J, Bauer, D, Bauer, P, Baxter, A, Belle, J, Beltrame, P, Bensinger, J, Benson, T, Bernard, EP, Bernstein, A, Bhatti, A, Biekert, A, Biesiadzinski, TP, Birrittella, B, Boast, KE, Bolozdynya, AI, Boulton, EM, Boxer, B, Bramante, R, Branson, S, Brás, P, Breidenbach, M, Buckley, JH, Bugaev, VV, Bunker, R, Burdin, S, Busenitz, JK, Campbell, JS, Carels, C, Carlsmith, DL, Carlson, B, Carmona-Benitez, MC, Cascella, M, Chan, C, Cherwinka, JJ, Chiller, AA, Chiller, C, Chott, NI, Cole, A, Coleman, J, Colling, D, Conley, RA, Cottle, A, Coughlen, R, Craddock, WW, Curran, D, Currie, A, Cutter, JE, da Cunha, JP, Dahl, CE, Dardin, S, Dasu, S, Davis, J, Davison, TJR, de Viveiros, L, Decheine, N, Dobi, A, Dobson, JEY, Druszkiewicz, E, Dushkin, A, Edberg, TK, Edwards, WR, Edwards, BN, Edwards, J, Elnimr, MM, Emmet, WT, Eriksen, SR, Faham, CH, Fan, A, Fayer, S, Fiorucci, S, Flaecher, H, Fogarty Florang, IM, Ford, P, Francis, VB, Froborg, F, Fruth, T, Gaitskell, RJ, Gantos, NJ, Garcia, D, Geffre, A, and Gehman, VM

Subjects
Dark matter detector, Liquid xenon, Time projection chamber, Underground, physics.ins-det, astro-ph.IM, hep-ex, Nuclear & Particles Physics, Astronomical and Space Sciences, Atomic, Molecular, Nuclear, Particle and Plasma Physics, Other Physical Sciences
Abstract

We describe the design and assembly of the LUX-ZEPLIN experiment, a direct detection search for cosmic WIMP dark matter particles. The centerpiece of the experiment is a large liquid xenon time projection chamber sensitive to low energy nuclear recoils. Rejection of backgrounds is enhanced by a Xe skin veto detector and by a liquid scintillator Outer Detector loaded with gadolinium for efficient neutron capture and tagging. LZ is located in the Davis Cavern at the 4850’ level of the Sanford Underground Research Facility in Lead, South Dakota, USA. We describe the major subsystems of the experiment and its key design features and requirements.

Published
2020

83. Bestandsaufnahme der verfügbaren und aktuell eingesetzten Typisierungsmethoden einschließlich genombasierter Verfahren von Zoonoseerregern am Beispiel von Salmonella enterica

Author

Pietsch, Michael, Simon, Sandra, Richter, Anne, Malorny, Burkhard, Uelze, Laura, Hepner, Sabrina, Dangel, Alexandra, Sing, Andreas, Huber, Ingrid, Busch, Ulrich, Linde, Jörg, Methner, Ulrich, Becker, Natalie, Werner, Guido, Mellmann, Alexander, Fruth, Angelika, and Flieger, Antje

Published
2023
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85. Assessing the effects of survey-inherent disturbance on primate detectability: Recommendations for line transect distance sampling

Author

Bessone, Mattia, Kühl, Hjalmar S., Hohmann, Gottfried, Herbinger, Ilka, N’Goran, K. Paul, Asanzi, Papy, Da Costa, Pedro B., Dérozier, Violette, Fotsing, D. B. Ernest, Ikembelo, B. Beka, Iyomi, D. Mpongo, Iyatshi, B. Iyomi, Kafando, Pierre, Kambere, A. Mbangi, Moundzoho, B. Dissondet, Musubaho, L. Kako, and Fruth, Barbara

Published
2023
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91. Structure elucidation and toxicological evaluation of cyclic Polyethersulfone oligomers present in extracts of membrane filters

Author

Menzel, Roberto, TanjaMaier, Tauscher, Eric, von Mertz, Franziska Spruner, Freiberger, Emma, Golz, Christopher, Fruth, Lothar, Pahl, Ina, and Hauk, Armin

Subjects
Polyethersulphones -- Structure -- Mechanical properties, Oligomers -- Structure -- Mechanical properties, Membranes (Technology) -- Materials, Toxicology -- Analysis, Engineering and manufacturing industries, Science and technology
Abstract

Abstract Polyethersulfone (PES) is a widely used polymer in consumer and technical products. An important application is PES membranes used in the biopharmaceutical industry for sterilizing-grade filtration and for filtration [...]

Published
2022
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92. Sporadic Occurrence of Enteroaggregative Shiga Toxin-Producing Escherichia coli O104:H4 Similar to 2011 Outbreak Strain

Author

Coipan, Claudia E., Friesema, Ingrid H., van den Beld, Maaike J.C., Bosch, Thijs, Schlager, Sabine, van der Voort, Menno, Frank, Christina, Lang, Christina, Fruth, Angelika, and Franz, Eelco

Subjects
Epidemics -- Causes of -- Netherlands, Escherichia coli infections -- Causes of, Escherichia coli -- Identification and classification -- Genetic aspects, Health
Abstract

Shiga toxin-producing Escherichia coli (STEC) is a zoonotic pathogen that causes illness ranging from mild diarrhea to hemolytic uremic syndrome and death. During 2011, an exceptionally large outbreak caused by [...]

Published
2022
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94. Projected WIMP sensitivity of the LUX-ZEPLIN (LZ) dark matter experiment

Author

Akerib, D. S., Akerlof, C. W., Alsum, S. K., Araújo, H. M., Arthurs, M., Bai, X., Bailey, A. J., Balajthy, J., Balashov, S., Bauer, D., Belle, J., Beltrame, P., Benson, T., Bernard, E. P., Biesiadzinski, T. P., Boast, K. E., Boxer, B., Brás, P., Buckley, J. H., Bugaev, V. V., Burdin, S., Busenitz, J. K., Carels, C., Carlsmith, D. L., Carlson, B., Carmona-Benitez, M. C., Chan, C., Cherwinka, J. J., Cole, A., Cottle, A., Craddock, W. W., Currie, A., Cutter, J. E., Dahl, C. E., de Viveiros, L., Dobi, A., Dobson, J. E. Y., Druszkiewicz, E., Edberg, T. K., Edwards, W. R., Fan, A., Fayer, S., Fiorucci, S., Fruth, T., Gaitskell, R. J., Genovesi, J., Ghag, C., Gilchriese, M. G. D., van der Grinten, M. G. D., Hall, C. R., Hans, S., Hanzel, K., Haselschwardt, S. J., Hertel, S. A., Hillbrand, S., Hjemfelt, C., Hoff, M. D., Hor, J. Y-K., Huang, D. Q., Ignarra, C. M., Ji, W., Kaboth, A. C., Kamdin, K., Keefner, J., Khaitan, D., Khazov, A., Kim, Y. D., Kocher, C. D., Korolkova, E. V., Kraus, H., Krebs, H. J., Kreczko, L., Krikler, B., Kudryavtsev, V. A., Kyre, S., Lee, J., Lenardo, B. G., Leonard, D. S., Lesko, K. T., Levy, C., Li, J., Liao, J., Liao, F. -T., Lin, J., Lindote, A., Linehan, R., Lippincott, W. H., Liu, X., Lopes, M. I., Paredes, B. López, Lorenzon, W., Luitz, S., Lyle, J. M., Majewski, P., Manalaysay, A., Mannino, R. L., Maupin, C., McKinsey, D. N., Meng, Y., Miller, E. H., Mock, J., Monzani, M. E., Morad, J. A., Morrison, E., Mount, B. J., Murphy, A. St. J., Nelson, H. N., Neves, F., Nikoleyczik, J., O'Sullivan, K., Olcina, I., Olevitch, M. A., Oliver-Mallory, K. C., Palladino, K. J., Patton, S. J., Pease, E. K., Penning, B., Piepke, A., Powell, S., Preece, R. M., Pushkin, K., Ratcliff, B. N., Reichenbacher, J., Rhyne, C. A., Richards, A., Rodrigues, J. P., Rosero, R., Rossiter, P., Saba, J. S., Sarychev, M., Schnee, R. W., Schubnell, M., Scovell, P. R., Shaw, S., Shutt, T. A., Silk, J. J., Silva, C., Skarpaas, K., Skulski, W., Solmaz, M., Solovov, V. N., Sorensen, P., Stancu, I., Stark, M. R., Stiegler, T. M., Stifter, K., Szydagis, M., Taylor, W. C., Taylor, R., Taylor, D. J., Temples, D., Terman, P. A., Thomas, K. J., Timalsina, M., To, W. H., Tomás, A., Tope, T. E., Tripathi, M., Tull, C. E., Tvrznikova, L., Utku, U., Va'vra, J., Vacheret, A., Verbus, J. R., Voirin, E., Waldron, W. L., Watson, J. R., Webb, R. C., White, D. T., Whitis, T. J., Wisniewski, W. J., Witherell, M. S., Wolfs, F. L. H., Woodward, D., Worm, S. D., Yeh, M., Yin, J., and Young, I.

Subjects
Astrophysics - Instrumentation and Methods for Astrophysics, Astrophysics - Cosmology and Nongalactic Astrophysics, High Energy Physics - Experiment, Physics - Instrumentation and Detectors
Abstract

LUX-ZEPLIN (LZ) is a next generation dark matter direct detection experiment that will operate 4850 feet underground at the Sanford Underground Research Facility (SURF) in Lead, South Dakota, USA. Using a two-phase xenon detector with an active mass of 7~tonnes, LZ will search primarily for low-energy interactions with Weakly Interacting Massive Particles (WIMPs), which are hypothesized to make up the dark matter in our galactic halo. In this paper, the projected WIMP sensitivity of LZ is presented based on the latest background estimates and simulations of the detector. For a 1000~live day run using a 5.6~tonne fiducial mass, LZ is projected to exclude at 90\% confidence level spin-independent WIMP-nucleon cross sections above $1.4 \times 10^{-48}$~cm$^{2}$ for a 40~$\mathrm{GeV}/c^{2}$ mass WIMP. Additionally, a $5\sigma$ discovery potential is projected reaching cross sections below the exclusion limits of recent experiments. For spin-dependent WIMP-neutron(-proton) scattering, a sensitivity of $2.3 \times 10^{-43}$~cm$^{2}$ ($7.1 \times 10^{-42}$~cm$^{2}$) for a 40~$\mathrm{GeV}/c^{2}$ mass WIMP is expected. With underground installation well underway, LZ is on track for commissioning at SURF in 2020., Comment: 14 pages, 11 figures

Published
2018
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97. Biomarker feedback intervention for smoking cessation among Alaska Native pregnant women: Randomized pilot study

Author

Patten, Christi A, Koller, Kathryn R, Flanagan, Christie A, Hiratsuka, Vanessa Y, Hughes, Christine A, Wolfe, Abbie W, Decker, Paul A, Fruth, Kristin, Brockman, Tabetha A, Korpela, Molly, Gamez, Diana, Bronars, Carrie, Murphy, Neil J, Hatsukami, Dorothy, Benowitz, Neal L, and Thomas, Timothy K

Subjects
Health Services and Systems, Health Sciences, Tobacco Smoke and Health, Cancer, Behavioral and Social Science, Comparative Effectiveness Research, American Indian or Alaska Native, Drug Abuse (NIDA only), Prevention, Clinical Trials and Supportive Activities, Clinical Research, Substance Misuse, Tobacco, Pediatric Research Initiative, 6.6 Psychological and behavioural, Prevention of disease and conditions, and promotion of well-being, 3.1 Primary prevention interventions to modify behaviours or promote wellbeing, Evaluation of treatments and therapeutic interventions, Reproductive health and childbirth, Respiratory, Good Health and Well Being, Adolescent, Adult, Alaska, Alaskan Natives, Cigarette Smoking, Cognitive Behavioral Therapy, Counseling, Feasibility Studies, Feedback, Female, Humans, Pilot Projects, Pregnancy, Pregnancy Complications, Pregnant Women, Prenatal Care, Smoking Cessation, Alaska Native, Cigarette smoking, Smoking cessation, Intervention, Biomarker feedback, Alaska Natives, Medical and Health Sciences, Psychology and Cognitive Sciences, Public Health, Health services and systems
Abstract

ObjectiveThere is some evidence for biomarker feedback when combined with cessation counseling for reducing smoking in pregnancy. This randomized controlled pilot study evaluated feasibility and potential efficacy of a social-cognitive theory (SCT)-based biomarker feedback intervention among pregnant Alaska Native (AN) smokers.MethodsParticipants were randomly assigned to receive three study calls (10-20 min each): (1) biomarker feedback intervention (n = 30) including personalized cotinine results and feedback on their baby's likely exposure to carcinogen metabolite NNAL, or (2) contact control usual care condition based on the 5As (n = 30). Assessments were conducted at baseline, post-treatment, and delivery.ResultsHigh rates of treatment compliance, study retention, and treatment acceptability were observed in both groups. 7-day point prevalence smoking abstinence rates at delivery verified with urinary cotinine were the same in both study groups (20% intent-to-treat analysis, 26% per-protocol). SCT-based measures did not change differentially from baseline by study group.ConclusionThis trial supports the feasibility and acceptability of providing biomarker feedback within the clinical care delivery system, but the intervention did not promote increased smoking cessation during pregnancy compared to usual care.Practice implicationsEfforts are needed to promote the usual care and to develop alternative biomarker feedback messaging for pregnant AN women.

Published
2019

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