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The fatigue of engineered components involves more than the fatigue of metals as studied in laboratories. The miniscule laboratory test pieces cannot represent the pre-existing macroscopic crack defects in real engineering components. This brief study illustrates five examples in which major cracks are pre-existing as a result of the presence of bifilm defects. The pre-existing defects account for up to 90 per cent of the failure of so-called fatigue failure. The presence of pre-existing bifilm defects is of overwhelming importance. It is, with regret, suggested that the attempts at the elimination of so-called fatigue failures by only studying fatigue is misguided. The so-called fatigue failures of engineering components can be understood and addressed by realizing the major contributions of bifilms.

Introduction Across the world, data sources to support learning in primary care (PC) lag far behind that of acute care. Having comparable data sources across jurisdictions is essential for scaling and spreading healthcare learnings. Objectives The purpose of this work was to 1) identify and develop indicators of PC performance using administrative data and 2) examine the comparability of indicator definitions across three Canadian provinces (Nova Scotia, Ontario, British Columbia). This work is valuable for demonstrating how to arrive at comparable administrative data indicators across jurisdictions with different care patterns. Methods The TRANSFORMATION study is a multi-province Canadian study of PC that aims to improve PC performance measurement reporting. We initially compiled a list of PC performance indicators that had been used with existing administrative data. We followed and documented an iterative process to achieve comparable indicator operationalizations across the three provinces in Canada. Results Our final list included 21 PC performance indicators pertaining to 1) technical care (n=4), 2) continuity of care (n=6), and 3) health services utilization (n=11). Establishing comparability between these PC performance indicators was possible. The main challenge was major differences in data characteristics and available resources including pre-existing algorithms used in each province to define the indicators. We present examples of these differences including the identification of patients with diabetes and of bone mineral density measurement. Conclusion Arriving at comparable definitions of PC performance indicators using administrative data is challenging and time-consuming, but possible — even without data pooling. Through an iterative and well-documented process, research teams and policy-makers can develop and establish comparability of PC performance indicators that can help in supporting continuous improvements in healthcare system performance. More work is necessary to standardize approaches and optimize the comparability of PC performance indicators across jurisdictions.

Background: There are ambitious overseas recruitment targets to alleviate current GP shortages in the UK. GP training in European Economic Area (EEA) countries is recognised by the General Medical Council (GMC) as equivalent UK training; non-EEA GPs must obtain a Certificate of Eligibility for General Practice Registration (CEGPR), demonstrating equivalence to UK-trained GPs. The CEGPR may be a barrier to recruiting GPs from non-EEA countries. It is important to facilitate the most streamlined route into UK general practice while maintaining registration standards and patient safety. Aim: To apply a previously published mapping methodology to four non-EEA countries: South Africa, US, Canada, and New Zealand. Design & setting: Desk-based research was undertaken. This was supplemented with stakeholder interviews. Method: The method consisted of: (1) a rapid review of 13 non-EEA countries using a structured mapping framework, and publicly available website content and country-based informant interviews; (2) mapping of five ‘domains’ of comparison between four overseas countries and the UK (healthcare context, training pathway, curriculum, assessment, and continuing professional development (CPD) and revalidation). Mapping of the domains involved desk-based research. A red, amber, or green (RAG) rating was applied to indicate the degree of alignment with the UK. Results: All four countries were rated ‘green’. Areas of differences that should be considered by regulatory authorities when designing streamlined CEGPR processes for these countries include: healthcare context (South Africa and US), CPD and revalidation (US, Canada, and South Africa), and assessments (New Zealand). Conclusion: Mapping these four non-EEA countries to the UK provides evidence of utility of the systematic method for comparing GP training between countries, and may support the UK’s ambitions to recruit more GPs to alleviate UK GP workforce pressures.

Abstract Background Around 17% of people attending UK cardiac rehabilitation programmes have depression. Optimising psychological wellbeing is a rehabilitation goal, but provision of psychological care is limited. We developed and piloted an Enhanced Psychological Care (EPC) intervention embedded within cardiac rehabilitation, aiming to test key areas of uncertainty to inform the design of a definitive randomised controlled trial (RCT) and economic evaluation. Methods An external pilot randomised controlled trial (RCT) randomised eight cardiac rehabilitation teams (clusters) to either usual care of cardiac rehabilitation provision (UC), or EPC in addition to UC. EPC comprised mental health care coordination and patient-led behavioural activation with nurse support. Adults eligible for cardiac rehabilitation following an acute coronary syndrome and identified with new-onset depressive symptoms during an initial nurse assessment were eligible. Measures were performed at baseline and 5- and 8-month follow-ups and compared between EPC and UC. Team and participant recruitment and retention rates, and participant outcomes (clinical events, depression, anxiety, health-related quality of life, patient experiences, and resource use) were assessed. Results Eight out of twenty teams were recruited and randomised. Of 614 patients screened, 55 were eligible and 29 took part (5%, 95% CI 3 to 7% of those screened), with 15 patient participants cluster randomised to EPC and 14 to UC. Nurse records revealed that 8/15 participants received the maximum number of EPC sessions offered; and 4/15 received no sessions. Seven out of fifteen EPC participants were referred to another NHS psychological service compared to none in UC. We followed up 27/29 participants at 5 months and 17/21 at 8 months. The mean difference (EPC minus UC) in depressive symptoms (Beck Depression Inventory) at follow-up (adjusting for baseline score) was 1.7 (95% CI − 3.8 to 7.3; N = 26) at 5 months and 4.4 (95% CI − 1.4 to 10.2; N = 17) at 8 months. Discussion While valued by patients and nurses, organisational and workload constraints are significant barriers to EPC implementation. There remains a need to develop and test new models of psychological care within cardiac rehabilitation. Our study offers important data to inform the design of future trials of similar interventions. Trial registration ISRCTN34701576. Registered on 29 May 2014. Funding details: UK NIHR HTA Programme (project 12/189/09).