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Objective: To assess the health-related quality of life (HRQL) of patients with chronic obstructive pulmonary disease (COPD) in 4 Gulf Council Cooperation (GCC) countries., Methods: We conducted a cross-sectional survey between December 2011 and March 2012 in the following countries: Kingdom of Saudi Arabia (Riyadh, Dammam, and Jeddah), Kuwait, Bahrain, and the United Arab Emirates. The HRQL was measured using the COPD Assessment Test (CAT) and the Chronic Respiratory Disease Questionnaire-Self-Administered Standardized questionnaire (CRQ-SAS)., Results: We recruited 120 patients from 6 centers in 4 countries. Their average forced expiratory volume (FEV)1 was 49.3% ( +/- 13.4) of predicted, and the ratio of FEV1 to forced vital capacity was 0.58 ( +/- 0.11). The average COPD Assessment Test (CAT) score was 20.4 +/- 7.6; CAT scores were highest for Riyadh (24.1 +/- 7.7) and lowest for Kuwait (18.5 +/- 9.2), with no significant difference between the centers. For the CRQ-SAS, the dyspnea domain score was 4.6 +/- 1.6, the fatigue domain score was 4.3 +/- 1.3, the emotional domain was 4.6 +/- 1.2, and the mastery domain was 4.8 +/- 1.4. The correlation coefficients of the association between the CAT score and the 4 domains of the CRQ-SAS for all of the centers combined was statistically significant., Conclusion: The CAT and CRQ-SAS revealed that the patients with COPD experienced a moderate to severe impact from the disease, and a considerably compromised quality of life in the GCC countries.

Objective: To produce a conceptually equivalent Arabic version of the Chronic Obstructive Pulmonary Disease (COPD) Assessment Test (CAT), and to assess its reliability., Methods: A prospective observational study was carried out from June 2010 to September 2010 at King Abdulaziz Medical City and King Khalid University Hospital, Riyadh, Saudi Arabia. We conducted this study in 2 phases. Phase 1: the translation of the CAT from English to Arabic, through forward and backward translation, as well as pilot testing. Phase 2: assessment of the test-retest reliability of the CAT for 45 patients with COPD who received optimal care by their pulmonologist., Results: This study was conducted on 45 participants. The CAT mean total (+/- SD) score at the test session was 10.7+/-5.8, and 9.2+/-4.5 at the re-test session. The interclass correlation of the total score was 0.9 (p=0.000076). The strongest correlation was for the item of confidence in leaving home with a value of 0.92 (p=0.000082), whereas the weakest was for the item related to sleep with a value of 0.53 (p=0.007)., Conclusion: The Arabic version of the CAT was found to be easy to administer, reliable, and had a strong interclass correlation reflecting stability over time and across the items.

Objective: To present the experience with the first pulmonary rehabilitation (PR) program in Saudi Arabia., Methods: The prospectively collected data of patients referred to PR program in Saudi Arabia over 30 months starting on July 2004, were reviewed. A standard outpatient PR was offered to those patients with chronic lung diseases. Those patients attended to were classified as adherent or non adherent. There data were analyzed, as well as, the reasons for non-adherence., Results: Out of 121 patients referred to the PR center during the study period, 89 (73.6%) attended PR program and 32 (26.4%) did not attend their initial appointment. Among 89 patients who attended the PR program, 51 (57.3%) were adherent, while 38 (42.7%) attended but were non-adherent. The demographic data and the basic physiological parameters of both groups were not significantly different. Reasons for non-adherence were: difficulties in transportation (34.2%), admission to the hospital (23.7%), and no specific reason (42.1%). Upon completion of the PR, the exercise parameters in the adherent group showed significant improvement in the 6 minutes walk distance, and the distance and time spent in the treadmill, arm ergometer, and bicycle., Conclusion: Implementing a PR program in a tertiary care centre in Saudi Arabia was feasible and led to marked improvement in exercise performance and overall physical fitness.