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International audience; BACKGROUND AND AIM: Previous studies have reported a decrease in air pollution following the enforcement of lockdown measures during the first wave of the COVID-19 pandemic. However, these investigations were mostly based on simple pre-post comparisons using past years as a reference, and did not assess the role of different policy interventions. In this contribution, we quantitatively evaluated the association between various lockdown measures and the decrease in NO2, O3, PM2.5, and PM10 levels across 47 European cities and the associated short-term mortality in the period of February-July 2020. METHODS: We used data from several chemical transport models developed by the Copernicus Atmosphere Monitoring Service (CAMS) to define trends in air pollution under business-as-usual and lockdown scenarios, thus removing differences due to weather conditions and other differences affecting pre-post comparisons. We then applied an advanced spatio-temporal Bayesian non-linear mixed effect model to determine the association with stringency indices of individual policy measures, allowing non-linear relationships and geographical correlations. RESULTS: The findings indicate evidence of non-linear relationships, with a stronger decrease in NO2 and to a lesser extent PMs under very strict lockdown regimes. The effects of lockdown measures vary geographically, with a stronger decline in pollution in Southern and Central Europe. The comparative analysis of separate lockdown policies suggests important differences across interventions. Specifically, actions linked to school/workplace closure, limitations on gatherings, and stay-at-home requirements had strong effects, while restrictions on internal movement and international travels showed little impact. The observed decrease in pollution potentially resulted in hundreds of avoided deaths across the European cities. CONCLUSIONS: This study provides important evidence on the differential impacts of various policies implemented during the COVID-19 pandemic in decreasing the level of pollutants in urban areas across Europe.

Governments were enforced to respond to SARS-CoV-2 virus spread by taking a wide range of policy measures. Several studies have reported a decrease in air pollution following the enforcement of lockdown measures during the first wave of the COVID-19 pandemic. However, these investigations were mostly based on simple pre-post comparisons using past years as a reference, and did not assess the role of different policy interventions. These responses offered an unprecedented opportunity to assess the effectiveness of several interventions to reduce air pollution levels worldwide. Using an accurate representation of business-as-usual and lockdown air pollution scenarios, provided by Copernicus Atmosphere Monitoring Service (CAMS), we quantitatively evaluated the association between policies responses to the COVID-19 pandemic with changes in NO2, O3, PM2.5, and PM10 levels in 47 European cities. We also estimated the short-term mortality in the period of February-July 2020. An advanced spatio-temporal Bayesian non-linear mixed effect model was performed to determine the association between air pollutant levels and stringency indices as well as individual policy measures. The results indicate non-linear relationships, with a stronger decrease in NO2 and to a lesser extent PM10 and PM2.5 at very strict policy levels. Differences across interventions were also identified, actions linked to school/workplace closure, limitations on gatherings, and stay-at-home requirements had strong effects, while restrictions on internal movement and international travels showed little impact. The observed decrease in pollution potentially resulted in hundreds of avoided deaths across the European cities. This project provides information that can help inform future policies on air pollution reduction.

Many regions of the world are now facing more frequent and unprecedentedly large wildfires. However, the association between wildfire-related PMFor this time series study, data on daily counts of deaths for all causes, cardiovascular causes, and respiratory causes were collected from 749 cities in 43 countries and regions during 2000-16. Daily concentrations of wildfire-related PM65·6 million all-cause deaths, 15·1 million cardiovascular deaths, and 6·8 million respiratory deaths were included in our analyses. The pooled RRs of mortality associated with each 10 μg/mShort-term exposure to wildfire-related PMAustralian Research Council, Australian National HealthMedical Research Council.

On behalf of the Multi-Country Multi-City Collaborative (MCC) Research Network.Background & Aim: Climate change is considered the most important environmental threat to human health. Substantial mortality and morbidity burden have been directly or indirectly attributed to climate-sensitive environmental stressors. However, limited quantitative evidence exists on how much of this burden can be attributed to man-made influences on climate. In this large health attribution study, we aimed at quantifying the proportion of excess heat-related mortality attributed to anthropogenic climate change in recent decades across 626 locations across 41 countries in various regions of the world included in MCC database.Methods: We first estimated the location-specific heat-mortality associations through two-stage time-series analyses with quasi-Poisson regression with distributed lag non-linear models and multivariate multilevel meta-regression using observed data. We then quantified the heat-related excess mortality in each location using daily modelled series derived from historical (factual) and preindustrial control (counterfactual) simulations from 5 general circulation models (ISIMIP2b database) in the period between 1991 and 2019. We finally computed the proportion of heat-related excess mortality attributable to anthropogenic influences as the difference between the two scenarios, with associated measures of uncertainty.Results: We found a steep increase in level of warming, expressed as the difference in annual average temperature between scenarios, with an average increase of 1.0°C (from 0.7°C to 1.2°C) across the 626 locations between 1991 and 2019. Overall excess heat-mortality fractions of 1.92% [95% confidence interval: 0.41, 3.25] and 1.28% [0.20, 2.50] were estimated under the factual and counterfactual scenarios, respectively, with an overall difference of 0.76% [0.25,1.74]. This translates to 33% of historical heat-excess mortality that can be attributed to anthropogenic climate change. Larger proportions were found in North America (46%), Central America (47%), South America (43%), South Africa (48%), Middle-East Asia (61%), South East-Asia (50%) and Australia (42%), although highly imprecise in most of cases.Conclusions: Our findings suggest that current warming driven by anthropogenic influences is already responsible for a considerable proportion of the heat-related mortality burden. These results stress the importance of strengthening current mitigation strategies to reduce further warming of the planet and related health impacts.

Introduction: Children constitute a subgroup of potential high vulnerability to heat. However, few studies have specifically focused on it. Our aim was to examine the association between summer tem...