343 results on '"Anne Davis"'
Search Results
52. Virtually, Anything is Possible: Implementation of an Electronic Patient Reported Outcome Platform Across A Multi-Center Radiation Oncology Department
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Natasha McMaster, Marianne Arab, Thomas Ashford, Sue Chisholm, Carol-Anne Davis, Michael Ha, Randy McKnight, Murali Rajaraman, Charlene Rodriguez, Rob Rutledge, Derek Wilke, and Amanda Caissie
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Radiological and Ultrasound Technology ,Radiology, Nuclear Medicine and imaging - Published
- 2022
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53. Venus (review)
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Basting, Anne Davis
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- 1997
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54. Development and enhancement of pathways created to Health and Social Care for clients in areas of family disadvantage in targeted Primary Schools in Sydney, Australia
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Erin Miller, Dan Sprange, Suzanne Ratcliff, Anne Davis, Deslyn Raymond, and John Eastwood
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Semi-structured interview ,Medical education ,Health (social science) ,Sociology and Political Science ,Community engagement ,Health Policy ,media_common.quotation_subject ,education ,Service provider ,Disadvantaged ,Integrated care ,Outreach ,Promotion (rank) ,Health promotion ,Psychology ,media_common - Abstract
Background: Healthy Homes and Neighbourhoods (HHAN) is an integrated care program that supports families where adults have complex health and social needs, often impacting on their children. HHAN also aims to engage with and enhance capacity of partner agencies and the community served. This prioritised pathway initially featured delivery of long term whole-of-family care coordination, flexible community visits, fast track Paediatric outreach clinics and consistent collaboration with schools. Over time, the pathway has been strengthened and the model of practice has been refined and expanded to address whole of school and community needs. The enhanced model includes indirect provision of consultation for a larger number of children and their families and the implementation of whole of school health promotion and community engagement initiatives. Aim: To improve the established service pathway for families and the school community. Method: Two local primary schools receive this pathway. The enhanced model uses qualitative measures in the health promotion programs commenced. Pre and post surveys will be completed by parents and students and semi structured interviews with school staff will be undertaken. Evidence of sustainability and incorporation into school operations will be recorded. The number of students receiving a consultative model will also be compared to the number of families referred for direct HHAN care coordination. Results: This is a unique care coordination pathway linking professionals from the health, social and education sectors. Results had been previously demonstrated with families referred for care coordination through patient reported outcome measures .This has enabled trust between service providers, particularly education and healthcare providers, to develop over time and enabled the pathway to be reviewed. The expanded model of care benefits more students and the broader community. Conclusion: Establishment of this pathway has challenged partners to develop a model using creative, non-standard methods of intervention. Families in these communities have multiple needs and face multiple barriers to care. This highlights the need for place-based integrated care initiatives such as Healthy Homes and Neighbourhoods to target the needs of disadvantaged communities. The enhanced model of practice is in early stages of implementation. Further study will focus on evaluation of these initiatives. more...
- Published
- 2021
55. Virulence of Five
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Gabriel O, Sacher, Carolyn F, Scagel, E Anne, Davis, Bryan R, Beck, and Jerry E, Weiland
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Phytophthora ,Oregon ,Rhododendron ,Virulence ,Plant Diseases - Abstract
Phytophthora root rot is a destructive disease of rhododendron that causes substantial losses of this nursery crop in infested field and container production areas. Historically
- Published
- 2021
56. 8. Creative Storytelling and Self-Expression among People with Dementia
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Anne Davis Basting
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Expression (architecture) ,medicine ,Dementia ,Psychology ,medicine.disease ,Developmental psychology ,Storytelling - Published
- 2020
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57. High density residential development in the city of Gold Coast
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Jeanette Anne Davis
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Product (business) ,education.field_of_study ,Geography ,Land use ,Local Government Act ,Population ,Control (management) ,Position (finance) ,education ,Environmental planning ,Tourism ,Unit (housing) - Abstract
This study deals primarily with multi -unit residential developmentnin the City of Gold Coast. The City of Gold Coast has been selectednas an area for study because of its outstanding rate of growthnInand the fact that, whilst unique in its position as a holiday City,nit is probably the forerunner of many such holiday Cities on thentemperate coast of Australia. Multi-unit residential development hasnbeen studied because it is the most obvious and most contentiousnbuilding form in the City.n There are three objectives of this study.n The first objective is to determine why multi-unit residentialndevelopments are being constructed at a rapid rate in the City.nThe second objective is to list and evaluate existing controlsnand constraints used by the Local Authority to control and shapenbuilding development within the City.n The third objective is the most important. It is to proposenalternatives to and improvements in the Local Authority planningncontrols.n It was found in the course of the study that the construction ofnmulti -unit residential development in the City is a product ofnmany factors including the historical development of the City,nthe age structure of the population and tourism. The trend towardsnconstruction of this particular building form is supported by marketndemand.n The planning controls currently used by the Local Authority werenfound largely to be inadequate and in some cases operating in anmanner which led to in efficient and undesirable land use.n The improvements and alternatives to the existing planning control snwhich have been suggested are not revolutionary in concept. They arennot meant to be. All suggestions made are those which could benaccepted within the constraints of the Local Government Act and thenconstraints of a conservative Local Authority. The alternatives arensound, promote an efficient and desirable use of land and may benutilized by the Local Authority within its current planning framework.n more...
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- 2020
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58. Soilborne
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Jerry E, Weiland, Carolyn F, Scagel, Niklaus J, Grünwald, E Anne, Davis, Bryan R, Beck, Zachary S L, Foster, and Valerie J, Fieland
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Phytophthora ,Northwestern United States ,Rhododendron ,Pythium ,Plant Diseases - Abstract
Rhododendron root rot is a severe disease that causes significant mortality in rhododendrons. Information is needed about the incidence and identity of soilborne
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- 2020
59. Variation in Disease Severity Caused by Phytophthora cinnamomi, P. plurivora, and Pythium cryptoirregulare on Two Rhododendron Cultivars
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Jerry E. Weiland, Niklaus J. Grünwald, E. Anne Davis, Val J. Fieland, Bryan R. Beck, and Carolyn F. Scagel
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Phytophthora ,0106 biological sciences ,0301 basic medicine ,Rhododendron ,Pythium cryptoirregulare ,Pythium ,Plant Science ,Phytophthora cinnamomi ,Plant Roots ,01 natural sciences ,Crop ,03 medical and health sciences ,Disease severity ,Ornamental plant ,Root rot ,Cultivar ,Plant Diseases ,biology ,food and beverages ,030108 mycology & parasitology ,biology.organism_classification ,Horticulture ,Disease Susceptibility ,Agronomy and Crop Science ,010606 plant biology & botany - Abstract
Rhododendrons are an important crop in the ornamental nursery industry, but are prone to Phytophthora root rot. Phytophthora root rot is a continuing issue on rhododendrons despite decades of research. Several Phytophthora species are known to cause root rot, but most research has focused on P. cinnamomi, and comparative information on pathogenicity is limited for other commonly encountered oomycetes, including Phytophthora plurivora and Pythium cryptoirregulare. In this study, three isolates each of P. cinnamomi, P. plurivora, and Py. cryptoirregulare were used to inoculate rhododendron cultivars Cunningham’s White and Yaku Princess at two different inoculum levels. All three species caused disease, especially at the higher inoculum level. P. cinnamomi and P. plurivora were the most aggressive pathogens, causing severe root rot, whereas Py. cryptoirregulare was a weak pathogen that only caused mild disease. Within each pathogen species, isolate had no influence on disease. Both P. cinnamomi and P. plurivora caused more severe disease on Cunningham’s White than on Yaku Princess, suggesting that the relative resistance and susceptibility among rhododendron cultivars might be similar for both pathogens. Reisolation of P. cinnamomi and P. plurivora was also greater from plants exhibiting aboveground symptoms of wilting and plant death and belowground symptoms of root rot than from those without symptoms. Results show that both P. cinnamomi and P. plurivora, but not Py. cryptoirregulare, are important pathogens causing severe root rot in rhododendron. This study establishes the risks for disease resulting from low and high levels of inoculum for each pathogen. Further research is needed to evaluate longer term risks associated with low inoculum levels on rhododendron health and to explore whether differences among pathogen species affect disease control. more...
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- 2018
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60. Improving patient outcomes and radiotherapy systems: A pan-Canadian approach to patient-reported outcome use
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Lisa Barbera, Amanda Caissie, Erika Brown, Michael Brundage, Michael Milosevic, Robert Olson, and Carol-Anne Davis
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Canada ,medicine.medical_specialty ,Quality management ,media_common.quotation_subject ,medicine.medical_treatment ,Treatment outcome ,030218 nuclear medicine & medical imaging ,03 medical and health sciences ,0302 clinical medicine ,Neoplasms ,medicine ,Humans ,Quality (business) ,Patient Reported Outcome Measures ,media_common ,Radiotherapy ,business.industry ,Radiotherapy Planning, Computer-Assisted ,General Medicine ,Medical radiation ,Radiation therapy ,Treatment Outcome ,030220 oncology & carcinogenesis ,Family medicine ,General partnership ,Patient-reported outcome ,Professional association ,business - Abstract
Standardized collection and use of clinical patient-reported outcomes (PRO) have potential to benefit the care of individual patients and improve radiotherapy system performance. Its centralized health-care system makes Canada a prime candidate to take a leader and collaborator role in international endeavors to promote expansion of patient-reported outcome collection and use in radiotherapy. The current review discusses the development of a pan-Canadian approach to PRO use, through a quality improvement initiative led by the Canadian Partnership for Quality Radiotherapy (CPQR), a unique partnership of Canadian radiotherapy professional organizations (Canadian Association of Radiation Oncology-CARO, Canadian Organization of Medical Physicists-COMP, and the Canadian Association of Medical Radiation Technologists-CAMRT). more...
- Published
- 2018
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61. Patterns of Practice in Canadian Radiation Treatment Centres: Results of a National Survey
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Amanda Bolderston, Luminita Nica, Marcia Smoke, Alison Giddings, John French, and Carol-Anne Davis
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Canada ,medicine.medical_specialty ,Palliative care ,Staffing ,Specialty ,Breast Neoplasms ,Cancer Care Facilities ,Radiology, Interventional ,030218 nuclear medicine & medical imaging ,Fiscal year ,03 medical and health sciences ,0302 clinical medicine ,Neoplasms ,Humans ,Medicine ,Radiology, Nuclear Medicine and imaging ,Medical physics ,Practice Patterns, Physicians' ,Physician's Role ,Pace ,Image-guided radiation therapy ,Response rate (survey) ,Radiological and Ultrasound Technology ,Radiation Therapist ,business.industry ,Palliative Care ,Health Care Surveys ,030220 oncology & carcinogenesis ,Female ,Radiotherapy, Intensity-Modulated ,business ,Radiotherapy, Image-Guided - Abstract
Purpose Radiation therapy has changed rapidly over the past decade due to the application of technological advances. A survey was conducted of radiation treatment centres in Canada to establish current patterns of practice across the country. Areas of inquiry included treatment techniques and image verification, as well as roles and responsibilities of radiation therapists (RTs). Methods and Materials In January 2016, a survey was sent to managers of the 46 radiation treatment centres in Canada. This survey sought information on a range of staffing and practice variables for the fiscal year 2014/2015. Results Of the 46 centres contacted, 37 centres responded, representing an 80.4% response rate. Survey results showed that the use of volumetric arc therapy and intensity-modulated radiation therapy is common across Canada for several anatomic sites, as well as the use of daily pretreatment image verification. A high degree of variability exists for imaging modality (two dimensional vs. three dimensional) for some sites, including brain, head and neck, and lung. RTs' responsibilities have expanded uniformly across the country, with RTs involved in organ-at-risk contouring and on-treatment image approval at the majority of centres. Despite this role expansion, specialty roles in areas of quality and applications expertise are still rare. Conclusions Radiation therapy in Canada has transitioned to high-technology treatment techniques with relative consistency across the country. There is, however, variation in the imaging modality used for daily verification. Canada may benefit from consensus guidelines on the application of three-dimensional imaging for treatment verification. While RTs have expanded their responsibilities, role definition for RTs working in supervisory or supporting positions has not kept pace at many centres and it is unclear if RTs are supported in their expanded accountabilities. more...
- Published
- 2018
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62. PH Professional Network: Comprehensive Evaluation and Ongoing Approach to Children With Down Syndrome Who Have Pulmonary Hypertension or Are at Risk of Developing Pulmonary Hypertension
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Anne Davis, Traci Housten, and Emma Olson Jackson
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medicine.medical_specialty ,Down syndrome ,business.industry ,medicine ,General Medicine ,Intensive care medicine ,medicine.disease ,business ,Pulmonary hypertension - Published
- 2019
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63. 468: TIMELY ALBUMIN INFUSION IS ASSOCIATED WITH A SHORTER HOSPITALIZATION IN CIRRHOTIC PATIENTS
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W. Ray Kim, Karthik. Raghunathan, Greg Martin, E. Anne Davis, Navreet Sindhwani, Christopher Blanchette, Santosh Telang, and Kunal Lodaya
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Critical Care and Intensive Care Medicine - Published
- 2021
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64. 467: TIMELY ALBUMIN INFUSION MAY IMPROVE SURVIVAL IN CIRRHOTIC PATIENTS: A U.S. CROSS-SECTIONAL STUDY
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W. Ray Kim, Karthik. Raghunathan, Greg Martin, E. Anne Davis, Navreet Sindhwani, Christopher Blanchette, Santosh Telang, and Kunal Lodaya
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Critical Care and Intensive Care Medicine - Published
- 2021
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65. 469: CIRRHOTIC PATIENTS WITH GREATER BASELINE SEVERITY OF ILLNESS EXPERIENCE HIGHER USE OF TIMELY ALBUMIN
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W. Ray Kim, Karthik. Raghunathan, Greg Martin, E. Anne Davis, Navreet Sindhwani, Christopher Blanchette, Santosh Telang, and Kunal Lodaya
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Critical Care and Intensive Care Medicine - Published
- 2021
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66. Looking back from loss: views of the self in Alzheimer's disease
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Basting, Anne Davis
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Seniors - Published
- 2003
67. Using the Arts to Promote Resiliency Among Persons with Dementia and Their Caregivers
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Roush, Robert E., primary, Braun, Michelle, additional, Basting, Anne Davis, additional, Winakur, Jerald, additional, Rosenberg, Francesca, additional, and McFadden, Susan H., additional
- Published
- 2010
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68. 116: Advancing Radiation Oncology Practice in Atlantic Canada (AROPAC)
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Nicole Harnett, Clare Summers, Jean-Philippe Pignol, Rebecca Wong, Robin Urquhart, Carol-Anne Davis, and Murali Rajaraman
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medicine.medical_specialty ,Oncology ,business.industry ,Radiation oncology ,Medicine ,Radiology, Nuclear Medicine and imaging ,Medical physics ,Hematology ,business - Published
- 2021
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69. Creative Storytelling and Self-Expression among People with Dementia
- Author
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BASTING, ANNE DAVIS, primary
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- 2006
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70. Global Side Effects: Counter-Clinics in Mental Health Care
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Elizabeth Anne Davis
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medicine.medical_specialty ,Health (social science) ,MEDLINE ,030227 psychiatry ,03 medical and health sciences ,0302 clinical medicine ,Nursing ,Anthropology ,medicine ,Self care ,Mental health care ,030212 general & internal medicine ,Psychology ,Psychiatry ,Cultural competence ,Introductory Journal Article - Published
- 2017
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71. 144: A Pan-Canadian Approach to Supporting The Collection and Utilization of Patient Reported Outcomes in Radiation Oncology: An Initiative of the Canadian Partnership for Quality Radiotherapy
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Michael Milosevic, Robert Olson, Carol-Anne Davis, Jennifer O'Donnell, Michael Brundage, Louise Bird, Lisa Barbera, Jennifer Croke, Erika Brown, and Amanda Caissie
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medicine.medical_specialty ,business.industry ,media_common.quotation_subject ,medicine.medical_treatment ,Hematology ,Radiation therapy ,Oncology ,General partnership ,Radiation oncology ,medicine ,Radiology, Nuclear Medicine and imaging ,Medical physics ,Quality (business) ,business ,media_common - Published
- 2020
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72. Randomized Trial of Medical versus Surgical Treatment for Refractory Heartburn
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William D. Chey, Andrew M Kaz, Bobby S. Chan, Robert M. Genta, Grant D. Huang, Kerry B. Dunbar, Anthony W. Kim, Joel H Rubenstein, Amir A. Ghaferi, Shirley C Paski, Stuart Warren, Vivian M. Sanchez, Tracey Serpi, Dawn Provenzale, Christian S. Jackson, Taewan Kim, Donald O. Castell, Loren Laine, Ronald S. Fernando, John G. Hunter, Rhonda F. Souza, Sandhya Lagoo-Deenadayalan, Thai H. Pham, Anne Davis-Karim, Roger P Tatum, Shelby D. Melton, David Lieberman, Erik C von Rosenvinge, Ziad F Gellad, Hiroshi Mashimo, Robert H. Lee, Wai-Kit Lo, Karen M. Jones, Brian R Smith, Kousick Biswas, Uma K Murthy, Jason Wallen, Stuart Jon Spechler, and Jonathan Pearl more...
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Adult ,Male ,medicine.medical_specialty ,Baclofen ,Drug Resistance ,Fundoplication ,030204 cardiovascular system & hematology ,law.invention ,03 medical and health sciences ,0302 clinical medicine ,Pharmacotherapy ,Randomized controlled trial ,Refractory ,Quality of life ,Heartburn ,law ,Internal medicine ,Surveys and Questionnaires ,otorhinolaryngologic diseases ,Medicine ,Humans ,030212 general & internal medicine ,Surgical treatment ,Omeprazole ,Veterans ,business.industry ,Muscle Relaxants, Central ,digestive, oral, and skin physiology ,Desipramine ,Proton Pump Inhibitors ,General Medicine ,Middle Aged ,humanities ,digestive system diseases ,Multicenter study ,Gastroesophageal Reflux ,Quality of Life ,Drug Therapy, Combination ,Female ,medicine.symptom ,business ,medicine.drug - Abstract
Heartburn that persists despite proton-pump inhibitor (PPI) treatment is a frequent clinical problem with multiple potential causes. Treatments for PPI-refractory heartburn are of unproven efficacy and focus on controlling gastroesophageal reflux with reflux-reducing medication (e.g., baclofen) or antireflux surgery or on dampening visceral hypersensitivity with neuromodulators (e.g., desipramine).Patients who were referred to Veterans Affairs (VA) gastroenterology clinics for PPI-refractory heartburn received 20 mg of omeprazole twice daily for 2 weeks, and those with persistent heartburn underwent endoscopy, esophageal biopsy, esophageal manometry, and multichannel intraluminal impedance-pH monitoring. If patients were found to have reflux-related heartburn, we randomly assigned them to receive surgical treatment (laparoscopic Nissen fundoplication), active medical treatment (omeprazole plus baclofen, with desipramine added depending on symptoms), or control medical treatment (omeprazole plus placebo). The primary outcome was treatment success, defined as a decrease of 50% or more in the Gastroesophageal Reflux Disease (GERD)-Health Related Quality of Life score (range, 0 to 50, with higher scores indicating worse symptoms) at 1 year.A total of 366 patients (mean age, 48.5 years; 280 men) were enrolled. Prerandomization procedures excluded 288 patients: 42 had relief of their heartburn during the 2-week omeprazole trial, 70 did not complete trial procedures, 54 were excluded for other reasons, 23 had non-GERD esophageal disorders, and 99 had functional heartburn (not due to GERD or other histopathologic, motility, or structural abnormality). The remaining 78 patients underwent randomization. The incidence of treatment success with surgery (18 of 27 patients, 67%) was significantly superior to that with active medical treatment (7 of 25 patients, 28%; P = 0.007) or control medical treatment (3 of 26 patients, 12%; P0.001). The difference in the incidence of treatment success between the active medical group and the control medical group was 16 percentage points (95% confidence interval, -5 to 38; P = 0.17).Among patients referred to VA gastroenterology clinics for PPI-refractory heartburn, systematic workup revealed truly PPI-refractory and reflux-related heartburn in a minority of patients. For that highly selected subgroup, surgery was superior to medical treatment. (Funded by the Department of Veterans Affairs Cooperative Studies Program; ClinicalTrials.gov number, NCT01265550.). more...
- Published
- 2019
73. Nevada County Wine
- Author
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Mary Anne Davis and Mary Anne Davis
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- Wineries--California--Nevada County--History, Wine and wine making--California--Nevada County--History
- Abstract
Nevada County's tumultuous wine history includes several booms and busts, starting in the 1850s when gold prospectors brought the first grapevines in their saddlebags. Economic downturns, prohibition and war all tried to kill the fledgling wine industry, but it hung on thanks to gentleman farmers and members of the mining industry who supplied a thirsty clientele. Today, although the mines have gone quiet, wineries are thriving in the hills of the Gold Country, and the pioneering spirit lives on in their distinctive vintages and growing techniques. Join author Mary Anne Davis as she explores the family vineyards of the California foothills. more...
- Published
- 2020
74. Cognitive-Developmental Stage Theories for Counseling
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Sprinthall, Norman A., primary, Peace, Sandra Deangelis, additional, and Kennington, Patricia Anne Davis, additional
- Published
- 2001
- Full Text
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75. The stages of age: the growth of senior theatre
- Author
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Bastin, Anne Davis
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Aged -- Health aspects -- Social aspects ,Drama festivals -- Social aspects -- Health aspects ,Drama -- Health aspects -- Social aspects ,Arts, visual and performing ,Social aspects ,Health aspects - Abstract
The odors drift in layers, the faint smell of urine, pierced by lemon disinfectant. My grandmother, 92, Sits up in bed and points a crooked finger out the nursing home [...]
- Published
- 1995
76. A pan-Canadian survey of peer review practices in radiation oncology
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Michael Brundage, Julie Rouette, Carol-Anne Davis, Paul Jugpal, Helmut Hollenhorst, Gunita Mitera, Amanda Caissie, and Jennifer O’Donnell
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Canada ,congenital, hereditary, and neonatal diseases and abnormalities ,medicine.medical_specialty ,Quality care ,Bioinformatics ,030218 nuclear medicine & medical imaging ,03 medical and health sciences ,0302 clinical medicine ,Documentation ,Surveys and Questionnaires ,Radiation oncology ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,Response rate (survey) ,business.industry ,Expert consensus ,eye diseases ,Oncology ,Curative treatment ,030220 oncology & carcinogenesis ,Family medicine ,Radiation Oncology ,sense organs ,business - Abstract
Peer review (PR) of treatment plans has been recognized internationally as a key component of quality care in radiation oncology programs (ROPs). We conducted a survey of Canadian ROPs to describe current PR practices and identify barriers/facilitators to PR optimization.A 42-item e-survey was sent to all Canadian ROPs (n = 44). Survey development was guided by expert consensus, literature review, and existing guidelines. One multidisciplinary response per ROP was requested.Response rate was 100.0% (44/44). All ROPs (100.0%) reported conducting some PR and rated its importance as 7/10 or higher (10 = extremely important). One-half of ROPs (52.3%) peer-reviewed80% of curative treatment plans. ROPs reported performing PR "always/almost always" pretreatment (38.6%) or before 25% of radiation therapy delivery (52.3%). The majority of ROPs reported recommending major plan changes in5% of plans (88.6%) and documenting findings in the medical record (58.1%). Barriers to PR were radiation oncologist availability (34.1%) and time constraints (27.3%). Facilitators included development of PR standards (97.7%) and education/support (90.9%).The ROPs perceive PR as highly important, but substantial variation in the extent, timing, and documentation of PR exists. The understanding of current PR activities, barriers, and facilitators will inform the development of initiatives to optimize PR in radiation oncology. more...
- Published
- 2016
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77. Patient engagement in radiation therapy
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Erika Brown, Sunshine J. Purificacion, John French, and Carol Anne-Davis
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Canada ,Service delivery framework ,media_common.quotation_subject ,medicine.medical_treatment ,Context (language use) ,03 medical and health sciences ,0302 clinical medicine ,Consistency (negotiation) ,Nursing ,Patient-Centered Care ,Humans ,Medicine ,Quality (business) ,030212 general & internal medicine ,Patient participation ,Quality of Health Care ,media_common ,Physician-Patient Relations ,Service quality ,Radiotherapy ,business.industry ,Health Policy ,Radiation therapy ,030220 oncology & carcinogenesis ,General partnership ,Practice Guidelines as Topic ,Patient Participation ,business - Abstract
Radiation therapy service quality is not only defined by the technical aspects of care—the patient’s involvement and satisfaction also contribute largely to determining the quality of care received. Although there have been recent increases in support for the development of patient engagement activities throughout Canada, the lack of guidance and knowledge of patient engagement techniques within the radiotherapy context limits implementation. Without processes to obtain first-hand insight from patients, the need for these programs is overlooked. With a commitment to improving quality and consistency of care, the Canadian Partnership for Quality Radiotherapy recognized the need for a set of national guidelines on patient engagement in radiation therapy service delivery. Making use of the perspectives and first-hand experience of patient representatives, this initiative aims to develop a pan-Canadian guidance document that radiation therapy centres can adopt for successful integration of patient engagement through core activities of service delivery. more...
- Published
- 2016
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78. Efficacy of reduced rate fumigant alternatives and methyl bromide against soilborne pathogens and weeds in western forest nurseries
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Jerry E. Weiland, Anne Davis, Willis R. Littke, Robert L. Edmonds, Timothy W. Miller, Bryan R. Beck, and John E. Browning
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0106 biological sciences ,biology ,Chloropicrin ,Fumigation ,Biological pest control ,food and beverages ,04 agricultural and veterinary sciences ,biology.organism_classification ,Weed control ,01 natural sciences ,Metam sodium ,chemistry.chemical_compound ,1,3-Dichloropropene ,Agronomy ,chemistry ,040103 agronomy & agriculture ,0401 agriculture, forestry, and fisheries ,Pythium ,Weed ,Agronomy and Crop Science ,010606 plant biology & botany - Abstract
Preplant soil fumigation is commonly used to control soilborne pathogens and weeds in forest seedling nurseries of Oregon and Washington. However, lower chemical inputs are desired to meet state and federal application regulations, to minimize buffer zone size requirements, and to help protect the environment. Therefore, the objectives of this research were to evaluate the efficacy of three reduced rate soil fumigants under totally impermeable film (TIF) in managing soilborne diseases and weeds, and to determine if combined applications of up to four biocontrol agents improved soilborne disease control. Reduced rates of methyl bromide, metam sodium, and 1,3-dichloropropene, all applied in combination with chloropicrin, were effective in decreasing soil populations of Pythium and Fusarium as well as the presence of Pythium in root debris from the previous crop. The roots of Douglas-fir (Pseudotsuga menziesii) seedlings transplanted into each fumigant treatment were also colonized less by Pythium and Fusarium than those transplanted into nonfumigated control plots. However, biocontrol treatments were not effective against either pathogen. Weed biomass and weeding times were also significantly reduced by fumigation. Application costs were similar for all three fumigant treatments, but seedling size was largest from the methyl bromide and metam sodium treatments followed by the 1,3-dichloropropene treatment. Based on the results of this study, reduced rates of methyl bromide, metam sodium, and 1,3-dichloropropene show promise in managing soilborne diseases and weeds in forest nurseries. more...
- Published
- 2016
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79. Early albumin improves survival in cirrhotic patients on diuretic therapy who develop significant acute kidney injury: real-world evidence in the United States
- Author
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W. Ray Kim, Karthik Raghunathan, Greg S. Martin, Elizabeth Anne Davis, Navreet Sindhwani, Santosh Telang, and Kunal Lodaya
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Hepatology - Published
- 2020
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80. Tu1682 EARLY ALBUMIN LEADS TO SHORTER HOSPITAL STAY IN CIRRHOTIC PATIENTS ON DIURETIC THERAPY WHO DEVELOP ACUTE KIDNEY INJURY: REAL-WORLD EVIDENCE IN THE UNITED STATES
- Author
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W. Ray Kim, Kunal Lodaya, Navreet S. Sindhwani, E. Anne Davis, Karthik Raghunathan, Gregory Martin, and Santosh Telang
- Subjects
medicine.medical_specialty ,Hepatology ,business.industry ,medicine.medical_treatment ,Gastroenterology ,Acute kidney injury ,Albumin ,Real world evidence ,medicine.disease ,Emergency medicine ,Medicine ,Diuretic ,business ,Hospital stay - Published
- 2020
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81. Late-summer Disease Symptoms in Western Washington Red Raspberry Fields Associated with Co-Occurrence of Phytophthora rubi, Verticillium dahliae, and Pratylenchus penetrans, but not Raspberry bushy dwarf virus
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Amy B. Peetz, Kim Graham, Bryan R. Beck, Jerry E. Weiland, Robert R. Martin, Jeremiah K. S. Dung, Anne Davis, Andres Reyes Gaige, Chris Benedict, Inga A. Zasada, Carolyn R. Scagel, and Lindsey D. Thiessen more...
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0106 biological sciences ,0301 basic medicine ,Phytophthora ,Washington ,Nematoda ,Population ,Plant Science ,Biology ,Verticillium ,01 natural sciences ,Plant Viruses ,03 medical and health sciences ,Plant virus ,Animals ,Verticillium dahliae ,education ,Pathogen ,Plant Diseases ,education.field_of_study ,biology.organism_classification ,Pratylenchus penetrans ,Blowing a raspberry ,Horticulture ,030104 developmental biology ,Agronomy ,Seasons ,Verticillium wilt ,Rubus ,Agronomy and Crop Science ,010606 plant biology & botany - Abstract
Sixty percent of the $109 million processed red raspberry industry of the United States occurs in northern Washington State. In 2012, late-summer symptoms of vascular wilt and root disease were observed in many raspberry plantings. These symptoms were initially attributed to Verticillium dahliae. However, diagnostic tests for the pathogen were often contradictory and other soilborne pathogens (Phytophthora rubi and Pratylenchus penetrans) or Raspberry bushy dwarf virus (RBDV) might also have been involved. Therefore, a survey was conducted in 2013 and 2014 to (i) establish the incidence and soil population levels of V. dahliae in red raspberry production fields, (ii) compare among diagnostic methods and laboratories for detecting and quantifying V. dahliae from raspberry field soil, and (iii) assess which pathogens are associated with late-summer disease symptoms of raspberry. Plant and soil samples were collected from 51 disease sites and 20 healthy sites located in 24 production fields. Samples were analyzed for the presence and quantity of each pathogen using traditional plating and extraction methods (V. dahliae, P. rubi, and P. penetrans), quantitative polymerase chain reaction (qPCR) (V. dahliae and P. rubi), and enzyme-linked immunosorbent assay (RBDV). Results showed that V. dahliae was present in 88% of the production fields and that detection of the pathogen differed by method and by laboratory: qPCR detected V. dahliae in the soil from approximately three times as many sites (51 of 71 total sites) as by plating on NP10 semi-selective medium (15 of 71 total sites). Soil populations of V. dahliae were slightly greater at disease sites, but the pathogen was detected with similar frequency from healthy sites and it was rarely isolated from diseased plants (4%). P. rubi, P. penetrans, and RBDV were also common in production fields (79, 91, and 53% of fields, respectively). Both P. rubi (soil and root samples) and P. penetrans (root populations only), but not RBDV, were more frequently found at disease sites than healthy sites, and the amount of P. rubi detected by qPCR was greater from disease sites than healthy sites. In addition, P. rubi was isolated from 27% of the symptomatic plants located at disease sites. Regardless of detection method, V. dahliae, P. rubi, and P. penetrans, either with or without RBDV, were more likely to co-occur at disease sites (73%) than healthy sites (35%), suggesting that a soilborne disease complex is present in raspberry production fields. Results indicate that P. rubi is the primary pathogen most strongly associated with late-summer symptoms of disease, but root populations of P. penetrans and higher soil populations of V. dahliae may also be of concern. Therefore, disease control methods should focus on all three soilborne pathogens. more...
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- 2019
82. Cain in early nineteenth-century literature: Traditional biblical stories revised to encompass contemporary advances in science
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Kara Anne Davis
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Literature ,History ,business.industry ,business ,Romance - Published
- 2018
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83. Effect of Repetitive Transcranial Magnetic Stimulation on Treatment-Resistant Major Depression in US Veterans: A Randomized Clinical Trial
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Gerald Georgette, Zhibao Mi, Steven D. Forman, Leanne M. Williams, Amit Etkin, Art Noda, J. Kaci Fairchild, Tamara Beale, Ciaran S. Phibbs, Jerome A. Yesavage, Kousick Biswas, Grant D. Huang, Michael E. Thase, Anne Davis-Karim, Mark S. George, and Ruth O'Hara more...
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Adult ,Male ,Suicide Prevention ,medicine.medical_specialty ,Population ,Poison control ,Veterans Health ,law.invention ,Stress Disorders, Post-Traumatic ,03 medical and health sciences ,Depressive Disorder, Treatment-Resistant ,0302 clinical medicine ,Randomized controlled trial ,Double-Blind Method ,law ,Internal medicine ,medicine ,Humans ,education ,Veterans Affairs ,Depression (differential diagnoses) ,Veterans ,Psychiatric Status Rating Scales ,education.field_of_study ,Intention-to-treat analysis ,business.industry ,Hamilton Rating Scale for Depression ,Middle Aged ,medicine.disease ,Transcranial Magnetic Stimulation ,United States ,030227 psychiatry ,Intention to Treat Analysis ,Psychiatry and Mental health ,Suicide ,Treatment Outcome ,Quality of Life ,Major depressive disorder ,Female ,business ,030217 neurology & neurosurgery - Abstract
Importance Treatment-resistant major depression (TRMD) in veterans is a major clinical challenge given the high risk for suicidality in these patients. Repetitive transcranial magnetic stimulation (rTMS) offers the potential for a novel treatment modality for these veterans. Objective To determine the efficacy of rTMS in the treatment of TRMD in veterans. Design, Setting, and Participants A double-blind, sham-controlled randomized clinical trial was conducted from September 1, 2012, to December 31, 2016, in 9 Veterans Affairs medical centers. A total of 164 veterans with TRD participated. Interventions Participants were randomized to either left prefrontal rTMS treatment (10 Hz, 120% motor threshold, 4000 pulses/session) or to sham (control) rTMS treatment for up to 30 treatment sessions. Main Outcomes and Measures The primary dependent measure of the intention-to-treat analysis was remission rate (Hamilton Rating Scale for Depression score ≤10, indicating that depression is in remission and not a clinically significant burden), and secondary analyses were conducted on other indices of posttraumatic stress disorder, depression, hopelessness, suicidality, and quality of life. Results The 164 participants had a mean (SD) age of 55.2 (12.4) years, 132 (80.5%) were men, and 126 (76.8%) were of white race. Of these, 81 were randomized to receive active rTMS and 83 to receive sham. For the primary analysis of remission, there was no significant effect of treatment (odds ratio, 1.16; 95% CI, 0.59-2.26; P = .67). At the end of the acute treatment phase, 33 of 81 (40.7%) of those in the active treatment group achieved remission of depressive symptoms compared with 31 of 83 (37.4%) of those in the sham treatment group. Overall, 64 of 164 (39.0%) of the participants achieved remission. Conclusions and Relevance A total of 39.0% of the veterans who participated in this trial experienced clinically significant improvement resulting in remission of depressive symptoms; however, there was no evidence of difference in remission rates between the active and sham treatments. These findings may reflect the importance of close clinical surveillance, rigorous monitoring of concomitant medication, and regular interaction with clinic staff in bringing about significant improvement in this treatment-resistant population. Trial Registration ClinicalTrials.gov Identifier:NCT01191333 more...
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- 2018
84. The Ongoing Struggle for Ethical Ideals: Justice and Human Rights
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Anne Davis
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Human rights ,Law ,media_common.quotation_subject ,Political science ,Justice (ethics) ,media_common - Published
- 2018
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85. 205 Bridging the Gap: Identifying Barriers to Enable the Integration of Tobacco Cessation Into Cancer Patient Care
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Murali Rajaraman, Natasha McMaster, and Carol-Anne Davis
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Bridging (networking) ,Oncology ,Nursing ,business.industry ,Medicine ,Radiology, Nuclear Medicine and imaging ,Hematology ,business ,Patient care - Published
- 2019
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86. 17 Development and Implementation of a Group Peer Review Process to Improve Quality Culture and Full Plan Review Compliance
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Tracy Day, Raymond Wright, Wladyslawa Cwajna, Peilong Zhang, Christine Baillie, Mammo Yewondwossen, Carol-Anne Davis, Helmut Hollenhorst, and Kerry Hanlon
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Oncology ,Quality culture ,Radiology, Nuclear Medicine and imaging ,Operations management ,Hematology ,Plan (drawing) ,Psychology ,Compliance (psychology) - Published
- 2019
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87. 67 Patient Engagement: A Pan-Canadian Survey of Radiotherapy Centres’ Current Practices
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Gabrielle Robin, Carol-Anne Davis, Michael Brundage, Ross Halperin, Amanda Caissie, Jennifer Croke, Erika Brown, Louise Bird, and Lianne Wilson
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Radiation therapy ,Oncology ,Nursing ,business.industry ,medicine.medical_treatment ,medicine ,Radiology, Nuclear Medicine and imaging ,Patient engagement ,Hematology ,Current (fluid) ,business - Published
- 2019
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88. Migrants in Translation: Caring and the Logics of Difference in Contemporary Italy. Cristiana Giordano. Berkeley: University of California Press. 2014. ix+288 pp
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Elizabeth Anne Davis
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Sociology and Political Science ,Arts and Humanities (miscellaneous) ,Anthropology ,Media studies ,Sociology ,Classics - Published
- 2015
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89. The Quest for Quality: Principles to Guide Medical Radiation Technology Practice
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Kathryn Moran, Caitlin Gillan, Brian Liszewski, Carol-Anne Davis, and John French
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Value (ethics) ,Quality management ,Radiological and Ultrasound Technology ,Standardization ,business.industry ,Best practice ,media_common.quotation_subject ,General partnership ,Medicine ,Radiology, Nuclear Medicine and imaging ,Organizational structure ,Quality (business) ,Engineering ethics ,business ,Quality policy ,media_common - Abstract
Quality is a ubiquitous term in medical radiation technology; technologists, programs, and organizations emphasize the importance of ‘‘quality care,’’ yet the concept of what is encompassed by the term, how it is built and measured, and who is the judge of whether it has been achieved, are often left undefined. This article will present theoretical definitions of quality, considering the value of professional, patient, and organization perspectives. Foundational quality principles and frameworks will be explored to highlight tools necessary to engage in ‘‘quality-related’’ activities and research at the individual, institutional, and systems level. Being equipped with an understanding of the work of Deming, the underpinnings of the lean strategy and the idea of continuous quality improvement will support technologists in contributing to evidence-based, high-quality, and safe practice. Building on these basics, concepts of complexity and standardization will be explored as they relate to achieving and maintaining quality given changing practice, focusing on personalized medicine, technological innovation, and best practice guidelines. Means to measure and evaluate quality will be presented, emphasizing the need for a structured approach. Using the work of the Canadian Partnership for Quality Radiotherapy as an example, key quality-related considerations, such as incident reporting, organizational structure, and quality culture will be discussed, with specific attention to roles within the team. When appropriately defined, measured, and evaluated, the quest for quality has the potential to improve safety and mitigate risk. Engaging technologists to assume strong roles in providing the highest quality of care will contribute positively at the level of the individual patient, the organization, and the system. R�� more...
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- 2015
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90. 'We've toiled without end': Publicity, Crisis, and the Suicide 'Epidemic' in Greece
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Elizabeth Anne Davis
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History ,Sociology and Political Science ,media_common.quotation_subject ,Consumption (sociology) ,Criminology ,Indeterminacy (literature) ,Object (philosophy) ,Politics ,Economy ,Ethnography ,Public sphere ,Narrative ,Publicity ,media_common - Abstract
This paper addresses the rising suicide rate in Greece since the economic crisis began in 2008. By 2011, Greek and international media were reporting the Greek suicide rate as the fastest rising in Europe; dozens of “spectacular” public suicides were taken as symptoms of an “epidemic.” In this paper, I explore different accounts of this “epidemic”: statistical studies and press reports on suicide since the crisis; notes written by people who committed or attempted suicide in public during the crisis; and narratives of suicidality from psychiatric patients before the crisis, in dialogue with local psychiatric epidemiologies. These accounts summon three axes of comparison around suicide in Greece: historical difference, defined by the economic crisis and the time before; locale, contrasting the public sphere of media coverage and consumption with a particular region distinguished by its “suicidogenic” features; and evidence, moving from the public discourse on suicide to clinical ethnographic research that I conducted in northeastern Greece a decade ago. I show that each way of accounting for suicide challenges the epistemologies and evidence at work in the others; the tensions and the interactions among them are signs of indeterminacy in suicide itself, taken as an object of inquiry. In the public discourse on the Greek crisis, the many meanings of suicide have been condensed and fixed as a politics of protest. Yet, I argue, comparison among epistemologies of suicide and recognition of its indeterminacy generate a space for thinking about suicide beyond the publicity of the crisis. more...
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- 2015
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91. Venus Suzan-Lori Parks
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Basting, Anne Davis
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- 1997
92. Student Blogs : How Online Writing Can Transform Your Classroom
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Anne Davis, Ewa McGrail, Anne Davis, and Ewa McGrail
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- Blogs in education, English language--Composition and exercises--C, Students--Blogs, Internet in education
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How do students become successful writers and excited about writing? Blogging or other online writing in your classroom can build literacies in all content areas by giving students the frequent writing practice that is missing in classrooms today. Students have to write to get better at writing. They need to write to an authentic audience— real people who are interested in what they have to say and are willing to comment back and engage in further conversation. Simply put, they need practice time in interactive writing. How might teachers do this? This book is the answer to this question. The book investigates blogs as digital spaces where students can practice writing and converse with an authentic audience. It focuses on idea development and gives students voice. Today's students already occupy or will inhabit new online spaces in the future. Schools and teachers must move forward with the students and embrace this world across the curriculum in purposeful and creative ways. This will transform schools and teacher classrooms! more...
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- 2017
93. Trial of Prazosin for Post-Traumatic Stress Disorder in Military Veterans
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Ying Lu, Mei-Chiung Shih, Anne Davis-Karim, Kimberly L Hart, Robert M. Swift, Jennifer M. Romesser, Grant D. Huang, Murray A. Raskind, Crystal L. Harris, Thomas A. Mellman, Robert A. Rosenheck, Elaine R Peskind, Hollie A Holmes, Bruce K. Chow, Theresa Gleason, Miles McFall, Christopher Reist, and Murray B. Stein more...
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Adult ,Male ,Sleep Wake Disorders ,medicine.medical_specialty ,Hospitals, Veterans ,Placebo ,law.invention ,Suicidal Ideation ,Stress Disorders, Post-Traumatic ,03 medical and health sciences ,0302 clinical medicine ,Primary outcome ,Randomized controlled trial ,Double-Blind Method ,law ,medicine ,Prazosin ,Humans ,Treatment Failure ,Suicidal ideation ,Veterans Affairs ,Veterans ,Psychiatric Status Rating Scales ,Dose-Response Relationship, Drug ,business.industry ,Traumatic stress ,General Medicine ,Middle Aged ,Combined Modality Therapy ,humanities ,United States ,030227 psychiatry ,Dreams ,Psychotherapy ,Psychiatric status rating scales ,Physical therapy ,Adrenergic alpha-1 Receptor Antagonists ,Female ,medicine.symptom ,business ,Sleep ,030217 neurology & neurosurgery ,medicine.drug - Abstract
In randomized trials, prazosin, an αWe recruited veterans from 13 Department of Veterans Affairs medical centers who had chronic PTSD and reported frequent nightmares. Participants were randomly assigned to receive prazosin or placebo for 26 weeks; the drug or placebo was administered in escalating divided doses over the course of 5 weeks to a daily maximum of 20 mg in men and 12 mg in women. After week 10, participants continued to receive prazosin or placebo in a double-blind fashion for an additional 16 weeks. The three primary outcome measures were the change in score from baseline to 10 weeks on the Clinician-Administered PTSD Scale (CAPS) item B2 ("recurrent distressing dreams"; scores range from 0 to 8, with higher scores indicating more frequent and more distressing dreams); the change in score from baseline to 10 weeks on the Pittsburgh Sleep Quality Index (PSQI; scores range from 0 to 21, with higher scores indicating worse sleep quality); and the Clinical Global Impression of Change (CGIC) score at 10 weeks (scores range from 1 to 7, with lower scores indicating greater improvement and a score of 4 indicating no change).A total of 304 participants underwent randomization; 152 were assigned to prazosin, and 152 to placebo. At 10 weeks, there were no significant differences between the prazosin group and the placebo group in the mean change from baseline in the CAPS item B2 score (between-group difference, 0.2; 95% confidence interval [CI], -0.3 to 0.8; P=0.38), in the mean change in PSQI score (between-group difference, 0.1; 95% CI, -0.9 to 1.1; P=0.80), or in the CGIC score (between-group difference, 0; 95% CI, -0.3 to 0.3; P=0.96). There were no significant differences in these measures at 26 weeks (a secondary outcome) or in other secondary outcomes. At 10 weeks, the mean difference between the prazosin group and the placebo group in the change from baseline in supine systolic blood pressure was a decrease of 6.7 mm Hg. The adverse event of new or worsening suicidal ideation occurred in 8% of the participants assigned to prazosin versus 15% of those assigned to placebo.In this trial involving military veterans who had chronic PTSD, prazosin did not alleviate distressing dreams or improve sleep quality. (Funded by the Department of Veterans Affairs Cooperative Studies Program; PACT ClinicalTrials.gov number, NCT00532493 .). more...
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- 2018
94. Strategies to Influence a Quality and Compliance Culture
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Betsy Macht and Anne Davis
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Engineering ,Total quality management ,business.industry ,media_common.quotation_subject ,05 social sciences ,Organizational culture ,Behavioural sciences ,Sustainable business ,0502 economics and business ,Management system ,050211 marketing ,Profitability index ,Quality (business) ,The Conceptual Framework ,Marketing ,business ,050203 business & management ,media_common - Abstract
Strategies to Influence a Quality and Compliance Culture by Betsy J. Macht MBA, Walden University, 2010 BS, The Pennsylvania State University, 1979 Doctoral Study Submitted in Partial Fulfillment of the Requirements for the Degree of Doctor of Business Administration Walden University August 2016 Abstract In drug, medical, and consumer products businesses, leaders should establish strategies that ensure production of quality products and drive profitability. Sales of defective or substandard products carry a potential risk of unintended effects on the consumer. The purpose of this single case study was to explore the strategies used by leaders to influence a culture of quality and compliance, leading to production of saleable products, andIn drug, medical, and consumer products businesses, leaders should establish strategies that ensure production of quality products and drive profitability. Sales of defective or substandard products carry a potential risk of unintended effects on the consumer. The purpose of this single case study was to explore the strategies used by leaders to influence a culture of quality and compliance, leading to production of saleable products, and business profitability. The conceptual framework of the theory of constraints served to guide the scope and data analysis for this study. Participants included ten individuals with a minimum of 5 years of experience at the study company, based in the northeast region of the U.S., in director, manager, and technical leader roles who participated in individual, telephone-based interviews. Additional data sources for methodological triangulation included observations during a tour of the headquarters site, and analysis of policies, procedures, annual reports, and publically available information. Data analysis included coding of the data and analysis to identify themes and patterns that identify the strategies leaders use to embed a culture of quality. The emergent themes in this study included: leadership, culture and habits, communications, and management systems and data analysis. The findings of this study may contribute to positive social change and improved business practice by providing tools and skills needed by business leaders to ensure product quality and business success. By consistently delivering quality products to the market, the organization builds a sustainable business where the community can benefit from a stable supply of jobs and the consumer from a reliable supply of products that safely meet customer needs. Strategies to Influence a Quality and Compliance Culture by Betsy J. Macht MBA, Walden University, 2010 BS, The Pennsylvania State University, 1979 Doctoral Study Submitted in Partial Fulfillment of the Requirements for the Degree of Doctor of Business Administration Walden University August 2016 Dedication I would like to dedicate this study to my parents, brothers, husband, and sons for their support, patience, and encouragement as I worked to achieve this goal. Acknowledgments I would like to thank my family, including my “younger sister”, and colleagues and friends for their support as I completed this journey. I would also like to thank the Walden University faculty and staff who have supported me during the DBA process. In particular, I would like to thank my chair, Dr. Anne Davis, for her patience and critical feedback driving me to deliver the best work possible. I would also like to thank my committee, Dr. R. Dwyer and Dr. J. Savard; and Dr. Doron Zilbershtein and Dr. Ann L. Claesson, both of whom mentored me at critical points early in my DBA journey. more...
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- 2018
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95. Diel ammonium fluxes of two caribbean reef corals and two macroalgae under low nutrient conditions
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Katharine Anne Davis
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chemistry.chemical_compound ,geography ,Nutrient ,Oceanography ,geography.geographical_feature_category ,chemistry ,Ecology ,Environmental science ,Ammonium ,Reef ,Diel vertical migration - Published
- 2017
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96. Time Machines
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Elizabeth Anne Davis
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- 2017
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97. Repetitive transcranial magnetic stimulation (rTMS) for treatment-resistant major depression (TRMD) Veteran patients: study protocol for a randomized controlled trial
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Kousick Biswas, Michael E. Thase, Tamara Beale, Anne Davis-Karim, Mark S. George, Allyson C. Rosen, Grant D. Huang, Margaret Windy McNerney, J. Kaci Fairchild, Jerome A. Yesavage, Gerald Georgette, David Pittman, Zhibao Mi, Steven D. Forman, Art Noda, and Ciaran S. Phibbs more...
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Research design ,medicine.medical_specialty ,Time Factors ,medicine.medical_treatment ,Medicine (miscellaneous) ,Prefrontal Cortex ,Neuropsychological Tests ,Transcranial Direct Current Stimulation ,law.invention ,03 medical and health sciences ,Study Protocol ,Depressive Disorder, Treatment-Resistant ,0302 clinical medicine ,Randomized controlled trial ,Clinical Protocols ,Double-Blind Method ,law ,Surveys and Questionnaires ,Repetitive transcranial magnetic stimulation (rTMS) ,medicine ,Humans ,Pharmacology (medical) ,Veterans Affairs ,Depression (differential diagnoses) ,lcsh:R5-920 ,Depressive Disorder, Major ,Transcranial direct-current stimulation ,business.industry ,Remission Induction ,Hamilton Rating Scale for Depression ,Hamilton Rating Scale for Depression (HRSD24) ,medicine.disease ,Treatment-resistant major depression (TRMD) ,United States ,030227 psychiatry ,Substance abuse ,Clinical trial ,Affect ,United States Department of Veterans Affairs ,Treatment Outcome ,Research Design ,Physical therapy ,lcsh:Medicine (General) ,business ,030217 neurology & neurosurgery - Abstract
Background Evaluation of repetitive transcranial magnetic stimulation (rTMS) for treatment-resistant major depression (TRMD) in Veterans offers unique clinical trial challenges. Here we describe a randomized, double-blinded, intent-to-treat, two-arm, superiority parallel design, a multicenter study funded by the Cooperative Studies Program (CSP No. 556) of the US Department of Veterans Affairs. Methods We recruited medical providers with clinical expertise in treating TRMD at nine Veterans Affairs (VA) medical centers as the trial local investigators. We plan to enroll 360 Veterans diagnosed with TRMD at the nine VA medical centers over a 3-year period. We will randomize participants into a double-blinded clinical trial to left prefrontal rTMS treatment or to sham (control) rTMS treatment (180 participants each group) for up to 30 treatment sessions. All participants will meet Diagnostic and statistical manual of mental disorders, 4 th edition (DSM-IV) criteria for major depression and will have failed at least two prior pharmacological interventions. In contrast with other rTMS clinical trials, we will not exclude Veterans with posttraumatic stress disorder (PTSD) or history of substance abuse and we will obtain detailed history regarding these disorders. Furthermore, we will maintain participants on stable anti-depressant medication throughout the trial. We will evaluate all participants on a wide variety of potential predictors of treatment response including cognitive, psychological and functional parameters. Discussion The primary dependent measure will be remission rate (Hamilton Rating Scale for Depression (HRSD24) ≤ 10), and secondary analyses will be conducted on other indices. Comparisons between the rTMS and the sham groups will be made at the end of the acute treatment phase to test the primary hypothesis. The unique challenges to performing such a large technically challenging clinical trial with Veterans and potential avenues for improvement of the design in future trials will be described. Trial registration ClinicalTrials.gov, NCT01191333. Registered on 26 August 2010. This report is based on the protocol version 4.6 amended in February 2016. All items from the World Health Organization Trial Registration Data Set are listed in Appendix A. Electronic supplementary material The online version of this article (doi:10.1186/s13063-017-2125-y) contains supplementary material, which is available to authorized users. more...
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- 2017
98. Virtually Certified: Development of an Online Oral Examination Phase for a National Advanced Practice Certification Model for Radiation Therapists in Canada
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Caitlin, Gillan, Amanda, Bolderston, Carol-Anne, Davis, Lisa, DiProspero, Susan, Fawcett, Donna, Lewis, Katherine, Smith, Marcia, Smoke, and Nicole, Harnett
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Observer Variation ,Canada ,Leadership ,Certification ,Professional Competence ,Radiotherapy ,Allied Health Personnel ,Humans ,Reproducibility of Results ,Clinical Competence ,Educational Measurement - Abstract
Following development of a framework to establish the scope of advanced practice for radiation therapists (APRTs), a Canadian certification process was built. This involved three independently-assessed phases: professional portfolio, case submission, and oral examination. The oral examination was to test the candidate's knowledge and capacity for decision-making. Development and piloting involved 3 elements: 1) content development, including relevant case selection, with accompanying high-fidelity imaging and resources; 2) harnessing of technology and ensuing logistics, given the desire to offer the examination online, maximizing accessibility and minimizing resources; and 3) examiner recruitment and preparation, involving a national call for interprofessional examiners, to assess across the spectrum of competencies. Each element was approached systematically, with modifications made iteratively. Three overarching challenges required ongoing attention and consideration: resource-intensiveness of building and validating cases, ensuring applicability and relevance of case content and "answers" across practice environments, and preparation of non-radiation therapist (oncologist and physicist) examiners regarding APRT standards. The resultant examination model is thought to be a robust assessment tool, well-regarded by candidates and examiners as fair and transparent, and complementary to the other certification phases. A consultatory pilot process supported establishment of a robust framework that is believed to be defensible and preliminarily valid. more...
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- 2017
99. The Information Is Out There
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Elizabeth Anne Davis
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Geography ,business.industry ,Accounting ,business ,Transparency (behavior) - Published
- 2017
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100. Quality control within the multicentre perfusion CT study of primary colorectal cancer (PROSPeCT): results of an iodine density phantom study
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Maria, Lewis, Vicky, Goh, Shaun, Beggs, Andrew, Bridges, Philip, Clewer, Anne, Davis, Trevelyan, Foy, Karen, Fuller, Jennifer, George, Antony, Higginson, Ian, Honey, Gareth, Iball, Steve, Mutch, Shellagh, Neil, Cat, Rivett, Andrew, Slater, David, Sutton, Nick, Weir, Sarah, Wayte, and S A, Taylor more...
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Quality Control ,medicine.medical_specialty ,Image quality ,chemistry.chemical_element ,Iterative reconstruction ,Radiation Dosage ,Iodine ,Imaging phantom ,Hounsfield scale ,medicine ,Image noise ,Humans ,Radiology, Nuclear Medicine and imaging ,Phantoms, Imaging ,business.industry ,Ultrasound ,Reproducibility of Results ,General Medicine ,chemistry ,Radiographic Image Interpretation, Computer-Assisted ,Radiology ,Tomography ,Colorectal Neoplasms ,Tomography, X-Ray Computed ,business ,Nuclear medicine ,Algorithms - Abstract
To assess the cross-centre consistency of iodine enhancement, contrast-to-noise ratio and radiation dose in a multicentre perfusion CT trial of colorectal cancer. A cylindrical water phantom containing different iodine inserts was examined on seven CT models in 13 hospitals. The relationship between CT number (Hounsfield units, HU) and iodine concentration (milligrams per millilitre) was established and contrast-to-noise ratios (CNRs) calculated. Radiation doses (CTDIvol, DLP) were compared across all sites. There was a linear relationship between CT number and iodine density. Iodine enhancement varied by a factor of at most 1.10, and image noise by at most 1.5 across the study sites. At an iodine concentration of 1 mg ml−1 and 100 kV, CNRs ranged from 3.6 to 4.8 in the 220-mm phantom and from 1.4 to 1.9 in the 300-mm phantom. Doses varied by a factor of at most 2.4, but remained within study dose constraints. Iterative reconstruction algorithms did not alter iodine enhancement but resulted in reduced image noise by a factor of at most 2.2, allowing a potential dose decrease of at most 80 % compared to filtered back projection (FBP). Quality control of CT performance across centres indicates that CNR values remain relatively consistent across all sites, giving acceptable image quality within the agreed dose constraints. • Quality control is essential in a multicentre setting to enable CT quantification. • CNRs in a body-sized phantom had the recommended value of at least 1.5. • CTDIs and DLPs varied by factors of 1.8 and 2.4 respectively. more...
- Published
- 2014
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