861 results on '"Anu, M."'
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52. Business schools’ competitive strategies: whose goals, which aims?
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Ojala, Anu M.
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- 2019
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53. Ladle slag cement – Characterization of hydration and conversion
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Adesanya, Elijah, Sreenivasan, Harisankar, Kantola, Anu M., Telkki, Ville-Veikko, Ohenoja, Katja, Kinnunen, Paivo, and Illikainen, Mirja
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- 2018
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54. The changing patterns of cardiovascular diseases and their risk factors in the states of India: the Global Burden of Disease Study 1990–2016
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Prabhakaran, Dorairaj, Jeemon, Panniyammakal, Sharma, Meenakshi, Roth, Gregory A, Johnson, Catherine, Harikrishnan, Sivadasanpillai, Gupta, Rajeev, Pandian, Jeyaraj D, Naik, Nitish, Roy, Ambuj, Dhaliwal, R S, Xavier, Denis, Kumar, Raman K, Tandon, Nikhil, Mathur, Prashant, Shukla, D K, Mehrotra, Ravi, Venugopal, K, Kumar, G Anil, Varghese, Chris M, Furtado, Melissa, Muraleedharan, Pallavi, Abdulkader, Rizwan S, Alam, Tahiya, Anjana, Ranjit M, Arora, Monika, Bhansali, Anil, Bhardwaj, Deeksha, Bhatia, Eesh, Chakma, Joy K, Chaturvedi, Pankaj, Dutta, Eliza, Glenn, Scott, Gupta, Prakash C, Johnson, Sarah C, Kaur, Tanvir, Kinra, Sanjay, Krishnan, Anand, Kutz, Michael, Mathur, Manu R, Mohan, Viswanathan, Mukhopadhyay, Satinath, Nguyen, Minh, Odell, Christopher M, Oommen, Anu M, Pati, Sanghamitra, Pletcher, Martin, Prasad, Kameshwar, Rao, Paturi V, Shekhar, Chander, Sinha, Dhirendra N, Sylaja, P N, Thakur, J S, Thankappan, Kavumpurathu R, Thomas, Nihal, Yadgir, Simon, Yajnik, Chittaranjan S, Zachariah, Geevar, Zipkin, Ben, Lim, Stephen S, Naghavi, Mohsen, Dandona, Rakhi, Vos, Theo, Murray, Christopher J L, Reddy, K Srinath, Swaminathan, Soumya, and Dandona, Lalit
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- 2018
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55. The increasing burden of diabetes and variations among the states of India: the Global Burden of Disease Study 1990–2016
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Tandon, Nikhil, Anjana, Ranjit M, Mohan, Viswanathan, Kaur, Tanvir, Afshin, Ashkan, Ong, Kanyin, Mukhopadhyay, Satinath, Thomas, Nihal, Bhatia, Eesh, Krishnan, Anand, Mathur, Prashant, Dhaliwal, R S, Shukla, D K, Bhansali, Anil, Prabhakaran, Dorairaj, Rao, Paturi V, Yajnik, Chittaranjan S, Kumar, G Anil, Varghese, Chris M, Furtado, Melissa, Agarwal, Sanjay K, Arora, Megha, Bhardwaj, Deeksha, Chakma, Joy K, Cornaby, Leslie, Dutta, Eliza, Glenn, Scott, Gopalakrishnan, N, Gupta, Rajeev, Jeemon, Panniyammakal, Johnson, Sarah C, Khanna, Tripti, Kinra, Sanjay, Kutz, Michael, Muraleedharan, Pallavi, Naik, Nitish, Odell, Chrisopher M, Oommen, Anu M, Pandian, Jeyaraj D, Parameswaran, Sreejith, Pati, Sanghamitra, Prasad, Narayan, Raju, D Sreebhushan, Roy, Ambuj, Sharma, Meenakshi, Shekhar, Chander, Shukla, Sharvari R, Singh, Narinder P, Thakur, J S, Unnikrishnan, Ranjit, Varughese, Santosh, Xavier, Denis, Zachariah, Geevar, Lim, Stephen S, Naghavi, Mohsen, Dandona, Rakhi, Vos, Theo, Murray, Christopher J L, Reddy, K Srinath, Swaminathan, Soumya, and Dandona, Lalit
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- 2018
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56. Intriguing Role of Gut-Brain Axis on Cognition with an Emphasis on Interaction with Papez Circuit
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Kumar, Nitesh, primary, Xavier, Joyal, additional, Anu, M., additional, Fathima, A.S., additional, and Ravichandiran, V., additional
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- 2023
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57. Perceived stigma regarding mental illnesses among rural adults in Vellore, Tamil Nadu, South India
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Apoorva Guttikonda, Aleena M Shajan, Adeline Hephzibah, Akhila S Jones, Jerlyn Susanna, Sunil Neethu, Sharon Poornima, Sarah M Jala, D Arputharaj, David John, Nehemiah Natta, Dolorosa Fernandes, Shalini Jeyapaul, Dimple Jamkhandi, H Ramamurthy Prashanth, and Anu M Oommen
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Mental illnesses ,perception ,stigma Key Message: A large proportion of the rural population perceives that there is a high stigma toward those with mental illnesses and their families. ,Psychiatry ,RC435-571 - Abstract
Background: Stigma is an important factor that determines whether individuals seek treatment for mental illnesses. Studies assessing public perceptions regarding mental illnesses are scarce in India. This study documents the stigma perceived by a rural population toward patients with mental illness and their families. Materials and Methods: A cross-sectional pilot study was done in five villages, selected by simple random sampling, from a rural block in Vellore, Tamil Nadu. Households in each village were selected by systematic random sampling. From the selected households, 150 subjects aged 18–65 years, without known mental disorders, were chosen by convenience sampling, based on availability. Stigma was assessed using the Devaluation of Consumers Scale (DCS) and Devaluation of Consumer's Families Scale (DCFS). Results: The proportion with high perceptions of stigma associated with mentally ill persons was 63.8%, among the 150 interviewed rural respondents (women: 112, median age: 37 years). The proportion which perceived that there was public stigma toward families of those with mental illnesses was 43.4%. Older respondents (>37 years) had higher perceptions of stigma (odds ratio: 2.07; 95% confidence interval: 1.02–4.20) than others. Conclusion: The high perception of stigma associated with persons who are mentally ill as well as their families needs to be kept in mind while planning interventions to decrease the treatment gap for psychiatric morbidity, especially in rural areas.
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- 2019
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58. Magnitude, Frequency, and Accumulation: Workload Among Injured and Uninjured Youth Basketball Players
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Lauren C. Benson, Oluwatoyosi B. A. Owoeye, Anu M. Räisänen, Carlyn Stilling, W. Brent Edwards, and Carolyn A. Emery
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load ,jump ,overuse ,inertial measurement unit ,principal components analysis ,Sports ,GV557-1198.995 - Abstract
Overuse injuries are common in basketball. Wearable technology enables the workload to be monitored in sport settings. However, workload–injury models lack a biological basis both in the metrics recorded and how workload is accumulated. We introduce a new metric for monitoring workload: weighted jump height, where each jump height is weighted to represent the expected effect of the jump magnitude on damage to the tendon. The objectives of this study were to use principal components analysis to identify distinct modes of variation in all workload metrics accumulated over 1, 2, 3, and 4 weeks and to examine differences among the modes of variation in workload metrics between participants before the injury and uninjured participants. Forty-nine youth basketball players participated in their typical basketball practices and games, and lower extremity injuries were classified as patellar or Achilles tendinopathy, other overuse, or acute. An inertial measurement unit recorded the number and height of all jumps, and session rating of perceived exertion was recorded. The previous 1-, 2-, 3-, and 4-week workloads of jump count, jump height, weighted jump height, and session rating of perceived exertion were summed for each participant-week. Principal components analysis explained the variance in the accumulated workload variables. Using the retained principal components, the difference between the workload of injured participants in the week before the injury and the mean workload of uninjured participants was described for patellar or Achilles tendinopathy, overuse lower extremity injury, and any lower extremity injury. Participants with patellar or Achilles tendinopathy and overuse lower extremity injuries had a low workload magnitude for all variables in the 1, 2, 3, and 4 weeks before injury compared with the weeks before no injury. Participants with overuse lower extremity injuries and any lower extremity injury had a high previous 1-week workload for all variables along with a low previous 3- and 4-week jump count, jump height, and weighted jump height before injury compared with the weeks before no injury. Weighted jump height represents the cumulative damage experienced by tissues due to repetitive loads. Injured youth basketball athletes had a low previous 3- and 4-week workloads coupled with a high previous 1-week workload.
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- 2021
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59. Warm-Ups and Coaches' Perceptions: Searching for Clues to Improve Injury Prevention in Youth Basketball
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Anu M. Räisänen, Oluwatoyosi B. A. Owoeye, Kimberley Befus, Carla van den Berg, Kati Pasanen, and Carolyn A. Emery
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athletic injuries ,sports injuries ,adolescent sports ,warming-up exercise ,implementation ,primary prevention ,Sports ,GV557-1198.995 - Abstract
Introduction: Regular use of neuromuscular training (NMT) warm-up programs improves performance and prevents injuries. However, low level of adoption of these programs remains a problem. Understanding the current warm-ups in youth basketball and coaches' perceptions on injury prevention can guide the design of superior implementation strategies. This study describes warm-ups in youth basketball and coaches' injury prevention-related knowledge, attitudes, beliefs, and information sources.Methods: Youth basketball coaches (n = 50) completed a preseason questionnaire. The questionnaire covered warm-up length, use of aerobic/agility/balance/strength/other exercises in the warm-up, injury-related knowledge, attitudes, beliefs, and sources of information.Results: Typical warm-up duration was ≤ 10 min (48.0% of coaches, 95% CI: ±13.8%). All coaches included aerobic exercises in their warm-up. Agility, strength, and balance exercises were utilized by 80.0% (95% CI: ±11.7%), 70.7% (95% CI: ±13.6%), and 26.8% (95% CI: ±13.6%) of coaches, respectively. Most coaches agreed to some extent that basketball injuries are preventable (94%) and that participating in a NMT warm-up program would reduce player's risk of injury (92%). Other coaches were identified as the most common source of information on warm-ups and injury prevention.Discussion: Coaches use parts of effective NMT warm-up programs, but balance exercises are not well adopted. Considering the level of evidence supporting the importance of balance exercises in injury prevention, it is crucial to improve the implementation of NMT warm-up programs in youth basketball, for example, through educational courses. As fellow coaches were identified as the most important source of information, coaches' role in knowledge translation should be emphasized.
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- 2021
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60. Sustainable Design of Indian Rural Roads with Reclaimed Asphalt Materials
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Saride, Sireesh, George, Anu M., Avirneni, Deepti, Munwar Basha, B., Sivakumar Babu, G.L., editor, Saride, Sireesh, editor, and Basha, B. Munwar, editor
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- 2017
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61. Is This the Real Life, or Is This Just Laboratory? A Scoping Review of IMU-Based Running Gait Analysis.
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Lauren C. Benson, Anu M. Räisänen, Christian A. Clermont, and Reed Ferber
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- 2022
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62. Ozone depletion, ultraviolet radiation, climate change and prospects for a sustainable future
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Barnes, Paul W., Williamson, Craig E., Lucas, Robyn M., Robinson, Sharon A., Madronich, Sasha, Paul, Nigel D., Bornman, Janet F., Bais, Alkiviadis F., Sulzberger, Barbara, Wilson, Stephen R., Andrady, Anthony L., McKenzie, Richard L., Neale, Patrick J., Austin, Amy T., Bernhard, Germar H., Solomon, Keith R., Neale, Rachel E., Young, Paul J., Norval, Mary, Rhodes, Lesley E., Hylander, Samuel, Rose, Kevin C., Longstreth, Janice, Aucamp, Pieter J., Ballaré, Carlos L., Cory, Rose M., Flint, Stephan D., de Gruijl, Frank R., Häder, Donat-P., Heikkilä, Anu M., Jansen, Marcel A. K., Pandey, Krishna K., Robson, T. Matthew, Sinclair, Craig A., Wängberg, Sten-Åke, Worrest, Robert C., Yazar, Seyhan, Young, Antony R., and Zepp, Richard G.
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- 2019
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63. Nations within a nation: variations in epidemiological transition across the states of India, 1990–2016 in the Global Burden of Disease Study
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Dandona, Lalit, Dandona, Rakhi, Kumar, G Anil, Shukla, D K, Paul, Vinod K, Balakrishnan, Kalpana, Prabhakaran, Dorairaj, Tandon, Nikhil, Salvi, Sundeep, Dash, A P, Nandakumar, A, Patel, Vikram, Agarwal, Sanjay K, Gupta, Prakash C, Dhaliwal, R S, Mathur, Prashant, Laxmaiah, Avula, Dhillon, Preet K, Dey, Subhojit, Mathur, Manu R, Afshin, Ashkan, Fitzmaurice, Christina, Gakidou, Emmanuela, Gething, Peter, Hay, Simon I, Kassebaum, Nicholas J, Kyu, Hmwe, Lim, Stephen S, Naghavi, Mohsen, Roth, Gregory A, Stanaway, Jeffrey D, Whiteford, Harvey, Chadha, Vineet K, Khaparde, Sunil D, Rao, Raghuram, Rade, Kirankumar, Dewan, Puneet, Furtado, Melissa, Dutta, Eliza, Varghese, Chris M, Mehrotra, Ravi, Jambulingam, P, Kaur, Tanvir, Sharma, Meenakshi, Singh, Shalini, Arora, Rashmi, Rasaily, Reeta, Anjana, Ranjit M, Mohan, Viswanathan, Agrawal, Anurag, Chopra, Arvind, Mathew, Ashish J, Bhardwaj, Deeksha, Muraleedharan, Pallavi, Mutreja, Parul, Bienhoff, Kelly, Glenn, Scott, Abdulkader, Rizwan S, Aggarwal, Ashutosh N, Aggarwal, Rakesh, Albert, Sandra, Ambekar, Atul, Arora, Monika, Bachani, Damodar, Bavdekar, Ashish, Beig, Gufran, Bhansali, Anil, Bhargava, Anurag, Bhatia, Eesh, Camara, Bilali, Christopher, D J, Das, Siddharth K, Dave, Paresh V, Dey, Sagnik, Ghoshal, Aloke G, Gopalakrishnan, N, Guleria, Randeep, Gupta, Rajeev, Gupta, Subodh S, Gupta, Tarun, Gupte, M D, Gururaj, G, Harikrishnan, Sivadasanpillai, Iyer, Veena, Jain, Sudhir K, Jeemon, Panniyamamkal, Joshua, Vasna, Kant, Rajni, Kar, Anita, Kataki, Amal C, Katoch, Kiran, Khanna, Tripti, Khera, Ajay, Kinra, Sanjay, Koul, Parvaiz A, Krishnan, Anand, Kumar, Avdhesh, Kumar, Raman K, Kumar, Rashmi, Kurpad, Anura, Ladusingh, Laishram, Lodha, Rakesh, Mahesh, P A, Malhotra, Rajesh, Mathai, Matthews, Mavalankar, Dileep, Mohan BV, Murali, Mukhopadhyay, Satinath, Murhekar, Manoj, Murthy, G V S, Nair, Sanjeev, Nair, Sreenivas A, Nanda, Lipika, Nongmaithem, Romi S, Oommen, Anu M, Pandian, Jeyaraj D, Pandya, Sapan, Parameswaran, Sreejith, Pati, Sanghamitra, Prasad, Kameshwar, Prasad, Narayan, Purwar, Manorama, Rahim, Asma, Raju, Sreebhushan, Ramji, Siddarth, Rangaswamy, Thara, Rath, Goura K, Roy, Ambuj, Sabde, Yogesh, Sachdeva, K S, Sadhu, Harsiddha, Sagar, Rajesh, Sankar, Mari J, Sharma, Rajendra, Shet, Anita, Shirude, Shreya, Shukla, Rajan, Shukla, Sharvari R, Singh, Gagandeep, Singh, Narinder P, Singh, Virendra, Sinha, Anju, Sinha, Dhirendra N, Srivastava, R K, Srividya, A, Suri, Vanita, Swaminathan, Rajaraman, Sylaja, P N, Tandale, Babasaheb, Thakur, J S, Thankappan, Kavumpurathu R, Thomas, Nihal, Tripathy, Srikanth, Varghese, Mathew, Varughese, Santosh, Venkatesh, S, Venugopal, K, Vijayakumar, Lakshmi, Xavier, Denis, Yajnik, Chittaranjan S, Zachariah, Geevar, Zodpey, Sanjay, Rao, J V R Prasada, Vos, Theo, Reddy, K Srinath, Murray, Christopher J L, and Swaminathan, Soumya
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- 2017
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64. Field Strength of Network-Modifying Cation Dictates the Structure of (Na-Mg) Aluminosilicate Glasses
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Harisankar Sreenivasan, Paivo Kinnunen, Elijah Adesanya, Minna Patanen, Anu M. Kantola, Ville-Veikko Telkki, Marko Huttula, Wei Cao, John L. Provis, and Mirja Illikainen
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aluminosilicate glasses ,cation field strength ,NMR ,XPS ,phase separation ,magnesium ,Technology - Abstract
Aluminosilicate glasses are materials with a wide range of technological applications. The field strength of network-modifying cations strongly influences the structure of aluminosilicate glasses and their suitability for various applications. In this work, we study the influence of the field strength of network-modifying cations on the structure of [(Na2O)1–x(MgO)x(Al2O3)0.25(SiO2)1.25] glasses. Due to the higher cation field strength of magnesium than sodium, magnesium prefers the role of network modifier, while sodium preferentially acts as a charge compensator. When magnesium replaces sodium as network modifier, Q3 silicon species are converted into Q2 species. The replacement of sodium with magnesium as charge compensator leads to the following changes: (1) the proportion of aluminum-rich Q4 species [Q4(4Al) and Q4(3Al)] decreases, while the proportion of aluminum-deficient Q4 species [Q4(2Al) and Q4(1Al)] increases; and (2) there is an increased tendency for phase separation between silica-rich and alumina-rich glasses.
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- 2020
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65. Prevalence of adolescent physical activity-related injuries in sports, leisure time, and school: the National Physical Activity Behaviour Study for children and Adolescents
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Anu M. Räisänen, Sami Kokko, Kati Pasanen, Mari Leppänen, Arja Rimpelä, Jari Villberg, and Jari Parkkari
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Athletic injury ,Injury prevention ,Youth ,Adolescents ,Safety ,Physical activity ,Diseases of the musculoskeletal system ,RC925-935 - Abstract
Abstract Background The purpose of this study was to investigate the prevalence of adolescent physical activity-related injuries in sports club activities, leisure time physical activity and school-based physical activity. The secondary aim was to investigate the differences in the prevalence of physical activity -related injuries between years 2014 and 2016. In addition, we set out to study the associations between age, sex and the frequency of physical activity and injury prevalence. Methods This cross-sectional study is based on the National Physical Activity Behaviour Study for Children and Adolescents (LIITU in Finnish) conducted in years 2014 and 2016. The subjects completed an online questionnaire in the classroom during school hours. A total of 8406 subjects participated in the current study. Out of these, 49% were boys and 51% were girls. The proportions of 11-, 13-, and 15-year-olds were 35%, 34% and 31%, respectively. Results In the combined data for 2014 and 2016, injury prevalence was higher in sports club activities (46%, 95% CI 44.8–47.8) than in leisure time PA (30%, 95% CI, 28.5–30.5) or school-based PA (18%, 95% CI, 17.4–19.1). In leisure time PA, the injury prevalence was higher than in school-based PA. In all the three settings, injury prevalence was higher in 2016 than in 2014. Frequency of PA was associated with a higher risk for PA-related injuries in sports clubs and leisure time. Conclusions With half of the subjects reporting at least one PA-related injury during the past year, results indicate that adolescent PA-related injuries are a large-scale problem. There is a worrisome rise in injury prevalence in recent years. From a public health standpoint, there is an urgent need to invest in injury prevention to reverse this trend.
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- 2018
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66. Effect of Milk Fat Globule Membrane- and Protein-Containing Snack Product on Physical Performance of Older Women—A Randomized Controlled Trial
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Jyväkorpi, Satu K., primary, Niskanen, Riikka T., additional, Markkanen, Marianna, additional, Salminen, Karoliina, additional, Sibakov, Timo, additional, Lehtonen, Kaity-Marin, additional, Kunvik, Susanna, additional, Pitkala, Kaisu H., additional, Turpeinen, Anu M., additional, and Suominen, Merja H., additional
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- 2023
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67. Assessment of patient medication adherence among the type 2 diabetes mellitus population with peripheral diabetic neuropathy in South India
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Samu, Anu M., Amirthalingam, Palanisamy S., and Mohammed, Osama S.
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- 2017
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68. The Epidemiology of Youth Sport-Related Shoulder Injuries: A Systematic Review
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Eric S. Gibson, Alexis Cairo, Anu M. Räisänen, Colleen Kuntze, Carolyn A. Emery, and Kati Pasanen
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Background. Youth around the globe place their shoulders at risk for injury when participating in sports. Shoulder injuries may vary in severity, produce the potential for time-loss from sport, and result in functional disability. We sought to explore sport-related shoulder injuries in youth by identifying injury rates, risk factors, injury mechanisms, and injury prevention strategies. Methods. All relevant full-text articles were identified by searching MEDLINE, EMBASE, CINAHL, Sport Discus, and the Cochrane Controlled Trials Registry. No date restrictions were used. All full-text studies reporting original research describing sport-related shoulder injury among female and/or male youth from 5 to 18 years old were included. Results. Of 3,889 studies screened, 97 described shoulder injury in youth sports. Shoulder injuries were identified in 24 unique sports. The median seasonal prevalence of shoulder injury was 10.9% (range 1.2–28.2%). The most common injury mechanisms identified were contacted with another player, contact with the playing environment, and falling to the ground. Risk factors for shoulder injury identified were side-to-side strength imbalances, weak external rotator muscles, and scapular dyskinesia. One study evaluated a successful training strategy to prevent shoulder injuries, but two other interventions demonstrated no effect. Conclusions. Sport-related shoulder injuries are prevalent among youth athletes. Injury risk factors identified included modifiable intrinsic factors such as strength, range of motion, and training load. The most common injury mechanism was direct contact with either another person or an object in the playing environment. Innovative shoulder-specific strategies are needed to reduce shoulder injuries in this population. Trial Registration: PROSPERO ID: CRD42020189142.
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- 2022
69. 'Outcast' as Indicated in Tamil Literature
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Anu M
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Microbiology - Abstract
During the Sangam period, Tamil Nadu flourished in all fields like literature, art, civilization, and politics. It is the Sangam literature that helps us to understand that famous society. That literature is full of historical sources, biographical events of the people, and internal and external events. The superiority of a country is determined by the lifestyles of its people. The literature that appeared in each period indicates the lifestyles of the people who lived in that period. The Sangam period, hailed as the golden age in the history of Tamil Nadu, had many special features. The Sangam literature that appeared at that time was also considered the cultural treasury of the people. It is also possible to clearly understand the lifestyles of the people of that time as described in the literature. There are ups and downs in the lives of the people of this era, where there is a lot of pride and fame. Tolkappiyam belongs to the early period of Tamil literary history. Both the studies of agathinai (internal life) and the genetics of Tolkaapiyam provide some information about the Varna system (sub divisions). The agathinai came to talk about the study of dividing them into four categories, namely king, noble, merchant, and servant. All these four are mentioned as "Eval Marapinar" (Commanding Lineage). That is, from Nachinarkinyar's explanation that "the business of inciting others is their own," it is clear that there was a section in society that obeyed the incitement of the four clans. This research paper tries to investigate the literature saying that the people who are engaged in this search are outcasts, their professional method, and the Varna (class) system of that time.
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- 2022
70. Corrigendum to “Investigation of the structure and ionic conductivity of a Li3InCl6 modified by dry room annealing for solid-state Li-ion battery applications” [Mater. Design 227 (2023) 111690]
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Molaiyan, Palanivel, Mailhiot, Sarah E., Voges, Kevin, Kantola, Anu M., Hu, Tao, Michalowski, Peter, Kwade, Arno, Telkki, Ville-Veikko, and Lassi, Ulla
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- 2024
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71. Effect of chemical exfoliation on the specific capacitance of MoS2 decorated conducting polymer electrodes for supercapacitor applications.
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Tomy, Merin, Anu, M. A., and Xavier, T. S.
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SUPERCAPACITOR electrodes , *CHEMICAL peel , *SUPERCAPACITORS , *POLYMER electrodes , *CONDUCTING polymers , *SURFACE area measurement , *MOLYBDENUM sulfides , *FIELD emission electron microscopy , *MOLYBDENUM disulfide - Abstract
The present communication introduces a modified high-performance supercapacitor electrode with chemically exfoliated MoS2@PANI nanocomposite as a solution for the upcoming energy needs. We put forward a chemical exfoliation route for increasing the effective surface area of hydrothermally synthesized MoS2, and effective encapsulation of a conducting polymer, polyaniline (PANI), was introduced via in-situ chemical oxidative polymerization of aniline monomer. The structural behaviors were systematically explored by X-ray diffraction (XRD), and Fourier-transform infrared spectroscopy (FT-IR), and the surface characteristics were analyzed by Field emission scanning electron microscopy (FE-SEM), and Brunauer–Emmett–Teller (BET) surface area measurements. The effect of exfoliation on capacitive performance was analyzed by the electrochemical study of two material platforms, MoS2@PANI and MoS2 ex@PANI, in a weakly acidic medium of 1 M H3PO4. The unique structure of MoS2 ex@PANI nanocomposite maximizes the ionic contact between the exfoliated MoS2 and PANI with electrolyte, which synergistically combines the double-layer and pseudocapacitive behavior of the individual compounds, thereby improving the conductivity and energy storage performance. The binary exfoliated composite electrodes revealed an excellent specific capacitance of 277 F g−1 at a scan rate of 5 mV s−1 superior to that of the MoS2@PANI electrode. A symmetric supercapacitor device was successfully developed and achieved improved capacitance of 128 F g−1 with impressive cyclic stability (98%) even after 15,000 cycles. The MoS2 ex@PANI nanocomposite becomes a future solution for existing supercapacitor electrodes for energy storage in lightweight wearable electronics. [ABSTRACT FROM AUTHOR]
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- 2023
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72. Effect of Milk Fat Globule Membrane- and Protein-Containing Snack Product on Physical Performance of Older Women—A Randomized Controlled Trial
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Suominen, Satu K. Jyväkorpi, Riikka T. Niskanen, Marianna Markkanen, Karoliina Salminen, Timo Sibakov, Kaity-Marin Lehtonen, Susanna Kunvik, Kaisu H. Pitkala, Anu M. Turpeinen, and Merja H.
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milk fat globule membrane ,older women ,protein ,5-time-chair-stand test ,balance ,SPPB - Abstract
Introduction: Sarcopenia is common in people 70+ years of age, and its prevalence increases with further aging. Insufficient energy and protein intake accelerates muscle loss, whereas sufficient protein intake and milk fat globule membrane (MFGM) may suppress age-associated deterioration of muscle mass and strength. Our objective was to test whether a snack product high in MFGM and protein would improve physical performance in older women. Methods: In this 12-week randomized controlled trial, women ≥ 70 years, with protein intake < 1.2 g/body weight (BW) kg/day (d), were randomized into intervention (n = 51) and control (n = 50) groups. The intervention group received a daily snack product containing ≥ 23 g of milk protein and 3.6–3.9 g of MFGM. Both groups were advised to perform a five-movement exercise routine. The primary outcome was the change in the five-time-sit-to-stand test between the groups. Secondary outcomes included changes in physical performance, cognition, hand grip strength, and health-related quality of life. Results: The change in the five-time-sit-to-stand test did not differ between the intervention and the control groups. The change in the total Short Physical Performance Battery score differed significantly, favoring the intervention group (p = 0.020), and the balance test showed the largest difference. Protein intake increased significantly in the intervention group (+14 g) compared to the control group (+2 g). No other significant changes were observed. Conclusions: Our results indicate that the combination of MFGM and protein may improve the physical performance-related balance of older women.
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- 2023
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73. Assessment of patient medication adherence among the type 2 diabetes mellitus population with peripheral diabetic neuropathy in South India
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Anu M. Samu, M.Pharm, Palanisamy S. Amirthalingam, Ph.D, and Osama S. Mohammed, MD
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داء السكري ,الالتزام بأخذ الدواء ,الاعتلال العصبي الطرفي ,مراقبة نسبة السكر بالدم ,تعليم المرضى ,Medicine (General) ,R5-920 - Abstract
أهداف البحث: حاولت هذه الدراسة استقصاء العلاقة بين عدم الالتزام بأخذ الدواء واعتلال الأعصاب الطرفي السكري بين مرضى السكري من النوع ٢ بمستشفى خاص في جنوب الهند. طرق البحث: أجريت دراسة مستقبلية خلال الفترة من يناير ٢٠١٥م وحتى ديسمبر ٢٠١٥م. شملت الدراسة ٨٦ مريضا بالسكري من النوع ٢ مع وجود اعتلال الأعصاب الطرفي السكري. تمت متابعة المرضى شهريا، ولمدة ثلاثة أشهر. أخذت عينات الدم لفحص مستوى السكر بالدم عند الصوم، وبعد الأكل بالإضافة إلى قياس مستوى الهيموغلوبين السكري. واستخدمت استبانة مقياس موريسكي لتقييم التزام المرضى لأخذ الدواء، ومقياس إدراك الاهتزاز لفحص درجة اعتلال الأعصاب الطرفي السكري. وجرى تقديم المشورة للمرضى أثناء كل متابعة بشأن مرضهم، والحاجة إلى مراقبة نسبة السكر بالدم، وأهمية الالتزام بأخذ الدواء. النتائج: من بين ١٢٠ مريضا تم فحصهم، شملت هذه الدراسة ٨٦ مريضا. كانت الغالبية (٧٦.٧٪) تعاني من زيادة الوزن، و٥١٪ منهم لديهم داء السكري منذ ١١-١٥ عاما. استخدمت طريقة أنوفا ذات الاتجاه الواحد لمقارنة وضع نسبة السكر في الدم، وفحص اعتلال الأعصاب الطرفي السكري والالتزام بأخذ الدواء في جميع الزيارات الثلاث. لوحظ تحسن كبير في الالتزام بأخذ الدواء والحد من شدة اعتلال الأعصاب الطرفي السكري من الزيارة الأولى للثالثة. الاستنتاجات: تعليم المرضى مهم لتحقيق الالتزام بأخذ الدواء ويمكن أن يُعزز مراقبة نسبة السكرالأمثل بالدم، ويقلل من انتشار اعتلال الأعصاب الطرفي السكري. يلعب ممارسي الرعاية الصحية دورا محوريا في تثقيف مرضى السكري بما يخص الالتزام بأخذ الدواء.
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- 2017
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74. Comparison of Measured and Observed Exercise Fidelity during a Neuromuscular Training Warm-Up
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Lauren C. Benson, Anu M. Räisänen, Sartaj S. Sidhu, and Carolyn A. Emery
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IMU ,soccer ,basketball ,youth ,repetitions ,impacts ,orientation ,General Medicine - Abstract
Neuromuscular training (NMT) warm-up programs effectively prevent injuries in youth, but monitoring exercise fidelity is challenging. The purpose of this study was to compare the exercise fidelity as measured via an inertial measurement unit (IMU) with direct observations of selected exercises. Youth basketball and soccer players performed single leg jumps, squat jumps, Nordic hamstring curls, and/or single leg balance exercises as part of an NMT warm-up. An IMU was placed on the lower back of each participant and the warm-up was video recorded. A physiotherapist evaluated the volume aspect of exercise fidelity (i.e., performing the prescribed number of repetitions) using the video recordings and a checklist. Algorithms were developed to count the number of repetitions from the IMU signal. The repetitions from the algorithms were compared with the physiotherapist’s evaluation, and accuracy, precision, and recall were calculated for each exercise. A total of 91 (39 female, 52 male) athletes performed at least one of the four warm-up exercises. There was an accuracy, precision, and recall of greater than 88% for all exercises. The single leg jump algorithm classified all sets correctly. IMUs may be used to quantify exercise volume for exercises that involve both impact during landing and changes in orientation during rotations.
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- 2022
75. In-hospital Outcomes Of Patients With Systemic Sclerosis Admitted For Heart Failure: An Analysis Of The National Inpatient Sample
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Abraham, Sonu S, primary, Gilvaz, Vinit J, additional, Sherif, Akil A, additional, Saji, Anu M, additional, and Venesy, David M, additional
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- 2023
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76. Who Does Not Respond to Injury Prevention Warm-up Programs? A Secondary Analysis of Trial Data From Neuromuscular Training Programs in Youth Basketball, Soccer, and Physical Education
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Räisänen, Anu M., primary, Galarneau, Jean-Michel, additional, van den Berg, Carla, additional, Eliason, Paul, additional, Benson, Lauren C., additional, Owoeye, Oluwatoyosi B. A., additional, Pasanen, Kati, additional, Hagel, Brent, additional, and Emery, Carolyn A., additional
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- 2023
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77. Encapsulation of xenon by bridged resorcinarene cages with high ¹²⁹Xe NMR chemical shift and efficient exchange dynamics
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Komulainen, S. (Sanna), Fernando, P. U. (P. U. Ashvin Iresh), Mareš, J. (Jiří), Selent, A. (Anne), Khalili, R. (Roya), Cesana, P. T. (Paul T.), Ebeling, A. (Andreas), Kantola, A. M. (Anu M.), Beyeh, N. K. (Ngong Kodiah), Rissanen, K. (Kari), DeBoef, B. (Brenton), Lantto, P. (Perttu), Telkki, V.-V. (Ville-Veikko), Komulainen, S. (Sanna), Fernando, P. U. (P. U. Ashvin Iresh), Mareš, J. (Jiří), Selent, A. (Anne), Khalili, R. (Roya), Cesana, P. T. (Paul T.), Ebeling, A. (Andreas), Kantola, A. M. (Anu M.), Beyeh, N. K. (Ngong Kodiah), Rissanen, K. (Kari), DeBoef, B. (Brenton), Lantto, P. (Perttu), and Telkki, V.-V. (Ville-Veikko)
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Functionalized cages encapsulating xenon atoms enable highly sensitive, background-free molecular imaging through a technique known as HyperCEST ¹²⁹Xe MRI. Here, we introduce a class of potential biosensor cage structures based on two resorcinarene macrocycles bridged either by aliphatic carbon chains or piperazines. First-principles-based modeling predicts a high chemical shift (about 345 ppm) outside the typical experimental observation window for ¹²⁹Xe encapsulated by the aliphatically bridged cage and two ¹²⁹Xe resonances for the piperazine-bridged cages corresponding to single and double loading. Based on the computational predictions as well as ¹²⁹Xe chemical exchange saturation transfer (CEST) and T₂ relaxation nuclear magnetic resonance experiments, we confirm Xe encapsulation in the aliphatically bridged and double encapsulation in the piperazine-bridged resorcinarene in methanol. The cages show fast Xe exchange rates (12,000–49,000 s⁻¹), resulting in a high CEST response regardless of the relatively low binding constant (0.09–3 M⁻¹).
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- 2023
78. Environmental Effects of Stratospheric Ozone Depletion, UV Radiation, and interactions with Climate Change: 2022 Assessment Report
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Andrady, Anthony L, Aucamp, Pieter J, Bais, Alkiviadis F, Barnes, Paul W, Bernhard, Germar H, Bornman, Janet F, Hader, D P, Heikkila, Anu M, Hylander, Samuel, Longstreth, Janice, Madronich, Sasha, Neale, Patrick J, Neale, Rachel, Pandey, Krishna K, Rhodes, Lesley E, Robinson, Sharon A, Robson, Matthew, Rose, Kevin C, Sulzberger, Barbara, Williamson, Craig E, White, Christopher C, Zepp, Richard G, Wilson, Stephen R, Wangberg, Sten-Ake, Yazar, Seyhan, Young, Antony R, Andrady, Anthony L, Aucamp, Pieter J, Bais, Alkiviadis F, Barnes, Paul W, Bernhard, Germar H, Bornman, Janet F, Hader, D P, Heikkila, Anu M, Hylander, Samuel, Longstreth, Janice, Madronich, Sasha, Neale, Patrick J, Neale, Rachel, Pandey, Krishna K, Rhodes, Lesley E, Robinson, Sharon A, Robson, Matthew, Rose, Kevin C, Sulzberger, Barbara, Williamson, Craig E, White, Christopher C, Zepp, Richard G, Wilson, Stephen R, Wangberg, Sten-Ake, Yazar, Seyhan, and Young, Antony R
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The Montreal Protocol on Substances that Deplete the Ozone Layer was established 35 years ago following the 1985 Vienna Convention for protection of the environment and human health against excessive amounts of harmful ultraviolet-B (UV-B, 280-315 nm) radiation reaching the Earth’s surface due to a reduced UV-B-absorbing ozone layer. The Montreal Protocol, ratified globally by all 198 Parties (countries), controls ca 100 ozone-depleting substances (ODS). These substances have been used in many applications, such as in refrigerants, air conditioners, aerosol propellants, fumigants against pests, fire extinguishers, and foam materials. The Montreal Protocol has phased out nearly 99% of ODS, including ODS with high global warming potentials such as chlorofluorocarbons (CFC), thus serving a dual purpose. However, some of the replacements for ODS also have high global warming potentials, for example, the hydrofluorocarbons (HFCs). Several of these replacements have been added to the substances controlled by the Montreal Protocol. The HFCs are now being phased down under the Kigali Amendment. As of December 2022, 145 countries have signed the Kigali Amendment, exemplifying key additional outcomes of the Montreal Protocol, namely, that of also curbing climate warming and stimulating innovations to increase energy efficiency of cooling equipment used industrially as well as domestically. As the concentrations of ODS decline in the upper atmosphere, the stratospheric ozone layer is projected to recover to pre-1980 levels by the middle of the 21st century, assuming full compliance with the control measures of the Montreal Protocol. However, in the coming decades, the ozone layer will be increasingly influenced by emissions of greenhouse gases and ensuing global warming. These trends are highly likely to modify the amount of UV radiation reaching the Earth's surface with implications for the effects on ecosystems and human health. Against this background, four Panels of expert
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- 2023
79. Investigation of the structure and ionic conductivity of a Li₃InCl₆ modified by dry room annealing for solid-state Li-ion battery applications
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Molaiyan, P. (Palanivel), Mailhiot, S. E. (Sarah E.), Voges, K. (Kevin), Kantola, A. M. (Anu M.), Hu, T. (Tao), Michalowski, P. (Peter), Kwade, A. (Arno), Telkki, V.-V. (Ville-Veikko), Lassi, U. (Ulla), Molaiyan, P. (Palanivel), Mailhiot, S. E. (Sarah E.), Voges, K. (Kevin), Kantola, A. M. (Anu M.), Hu, T. (Tao), Michalowski, P. (Peter), Kwade, A. (Arno), Telkki, V.-V. (Ville-Veikko), and Lassi, U. (Ulla)
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Progress in new sustainable technologies depends on the development of battery materials, specifically on safer, low-cost, and higher energy density batteries. One new type of materials are the halide solid electrolytes (HSEs), which have been shown to exhibit high ionic conductivity, deformability, and oxidative stability. Here, the synthesis of Li₃InCl₆ (LIC) HSEs by ball-milling followed by dry room annealing is investigated. Crystal structure, particle size, and ionic conductivity are analyzed using a combination of X-ray diffraction, transmission electron microscopy, and electrochemical impedance spectroscopy. Dry room annealing increases the presence of impurities in the sample but also increases the Li⁺ ionic conductivity up to 1.03 mS cm⁻¹. Additional pulsed-field gradient and relaxation time NMR measurements were performed to understand the lithium diffusion in the LIC samples. Two-dimensional diffusion — T₂ relaxation correlation and T₂ relaxation exchange measurements showed that there are multiple unique Li atomic motion sites, which are correlated to different rates of diffusive, micrometer-scale motion. This work outlines a simple solid-state synthesis approach and a novel strategy for designing advanced materials, understanding the ionic conduction, as well as the challenges in scalable wet processing of halide-based cathode sheets for solid-state battery applications.
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- 2023
80. Up front and open, shrouded in secrecy, or somewhere in between? A Meta Research Systematic Review of Open Science Practices in Sport Medicine Research
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Bullock, Garrett S, Ward, Patrick, Impellizzeri, Franco M, Kluzek, Stefan, Hughes, Tom, Hillman, Charles, Waterman, Brian R, Danelson, Kerry, Henry, Kaitlin, Barr, Emily, Healey, Kelsey, Räisänen, Anu M, Gomez, Christina, Fernandez, Garrett, Wolf, Jakob, Nicholson, Kristen F, Sell, Tim, Zerega, Ryan, Dhiman, Paula, Riley, Richard D, Collins, Gary S, Bullock, Garrett S, Ward, Patrick, Impellizzeri, Franco M, Kluzek, Stefan, Hughes, Tom, Hillman, Charles, Waterman, Brian R, Danelson, Kerry, Henry, Kaitlin, Barr, Emily, Healey, Kelsey, Räisänen, Anu M, Gomez, Christina, Fernandez, Garrett, Wolf, Jakob, Nicholson, Kristen F, Sell, Tim, Zerega, Ryan, Dhiman, Paula, Riley, Richard D, and Collins, Gary S
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OBJECTIVE: To investigate open science practices in research published in the top 5 sports medicine journals from May 1, 2022, and October 1, 2022. DESIGN: A meta-research systematic review. LITERATURE SEARCH: Open science practices were searched in MEDLINE. STUDY SELECTION CRITERIA: We included original scientific research published in one of the identified top 5 sports medicine journals in 2022 as ranked by Clarivate: (1) British Journal of Sports Medicine, (2) Journal of Sport and Health Science, (3) American Journal of Sports Medicine, (4) Medicine and Science in Sports and Exercise, and (5) Sports Medicine-Open. Studies were excluded if they were systematic reviews, qualitative research, gray literature, or animal or cadaver models. DATA SYNTHESIS: Open science practices were extracted in accordance with the Transparency and Openness Promotion guidelines and patient and public involvement. RESULTS: Two hundred forty-three studies were included. The median number of open science practices in each study was 2, out of a maximum of 12 (range: 0-8; interquartile range: 2). Two hundred thirty-four studies (96%, 95% confidence interval [CI]: 94%-99%) provided an author conflict-of-interest statement and 163 (67%, 95% CI: 62%-73%) reported funding. Twenty-one studies (9%, 95% CI: 5%-12%) provided open-access data. Fifty-four studies (22%, 95% CI: 17%-27%) included a data availability statement and 3 (1%, 95% CI: 0%-3%) made code available. Seventy-six studies (32%, 95% CI: 25%-37%) had transparent materials and 30 (12%, 95% CI: 8%-16%) used a reporting guideline. Twenty-eight studies (12%, 95% CI: 8%-16%) were preregistered. Six studies (3%, 95% CI: 1%-4%) published a protocol. Four studies (2%, 95% CI: 0%-3%) reported an analysis plan a priori. Seven studies (3%, 95% CI: 1%-5%) reported patient and public involvement. CONCLUSION: Open science practices in the sports medicine field are extremely limited. The least followed practices were sharing code, data, and analysi
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- 2023
81. United Nations Environment Programme (UNEP), Questions and Answers about the Effects of Ozone Depletion, UV Radiation, and Climate on Humans and the Environment. Supplement of the 2022 Assessment Report of the UNEP Environmental Effects Assessment Panel
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Andersen, Mads P. Sulbaek, Andrady, Anthony L, Bais, Alkiviadis F, Barnes, Paul, Bernhard, Germar H, Byrne, Scott N, Heikkila, Anu M, Ireland, Rachael, Jansen, Marcel A. K, Madronich, Sasha, McKenzie, Richard L, Neale, Rachel, Neale, Patrick J, Ossola, Rachele, Wang, Qing-Wei, Wangberg, Sten-Ake, White, Christopher C, Wilson, Stephen R, Zepp, Richard G, Robinson, Sharon A, Andersen, Mads P. Sulbaek, Andrady, Anthony L, Bais, Alkiviadis F, Barnes, Paul, Bernhard, Germar H, Byrne, Scott N, Heikkila, Anu M, Ireland, Rachael, Jansen, Marcel A. K, Madronich, Sasha, McKenzie, Richard L, Neale, Rachel, Neale, Patrick J, Ossola, Rachele, Wang, Qing-Wei, Wangberg, Sten-Ake, White, Christopher C, Wilson, Stephen R, Zepp, Richard G, and Robinson, Sharon A
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This collection of Questions & Answers (Q&As) was prepared by the Environmental Effects Assessment Panel (EEAP) of the Montreal Protocol under the umbrella of the United Nations Environment Programme (UNEP). The document complements EEAP’s Quadrennial Assessment 2022 (https://ozone. unep.org/science/assessment/eeap) and provides interesting and useful information for policymakers, the general public, teachers, and scientists, written in an easy-to-understand language.
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- 2023
82. United Nations Environment Programme (UNEP), Plastics in the environment in the context of UV radiation, climate change and the Montreal Protocol. 2023 Assessment Update of the UNEP Environmental Effects Assessment Panel
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Jansen, Marcel A. K, Andrady, Anthony L, Bornman, Janet F, Aucamp, Pieter J, Bais, Alkiviadis F, Banaszak, Anastazia T, Barnes, Paul W, Bernhard, Germar H, Bruckman, Laura S, Busquets, Rosa, Hader, Donat P, Hanson, Mark L, Heikkila, Anu M, Hylander, Samuel, Lucas, Robyn M, Mackenzie, Roy, Madronich, Sasha, Neale, Patrick J, Neale, Rachel E, Olsen, Catherine M, Ossola, Rachele, Pandey, Krishna K, Petropavlovskikh, Irina, Revell, Laura E, Robinson, Sharon A, Robson, T Matthew, Rose, Kevin C, Solomon, Keith R, Sulbaek Andersen, Mads P, Sulzberger, Barbara, Wallington, Timothy J, Wang, Qing-Wei, Wangberg, Sten-Ake, White, Christopher C, Young, Antony R, Zepp, Richard G, Zhu, Liping, Jansen, Marcel A. K, Andrady, Anthony L, Bornman, Janet F, Aucamp, Pieter J, Bais, Alkiviadis F, Banaszak, Anastazia T, Barnes, Paul W, Bernhard, Germar H, Bruckman, Laura S, Busquets, Rosa, Hader, Donat P, Hanson, Mark L, Heikkila, Anu M, Hylander, Samuel, Lucas, Robyn M, Mackenzie, Roy, Madronich, Sasha, Neale, Patrick J, Neale, Rachel E, Olsen, Catherine M, Ossola, Rachele, Pandey, Krishna K, Petropavlovskikh, Irina, Revell, Laura E, Robinson, Sharon A, Robson, T Matthew, Rose, Kevin C, Solomon, Keith R, Sulbaek Andersen, Mads P, Sulzberger, Barbara, Wallington, Timothy J, Wang, Qing-Wei, Wangberg, Sten-Ake, White, Christopher C, Young, Antony R, Zepp, Richard G, and Zhu, Liping
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This Assessment Update by the Environmental Effects Assessment Panel (EEAP) of the United Nations Environment Programme (UNEP) considers the interactive effects of solar UV radiation, global warming, and other weathering factors on plastics. The Assessment illustrates the significance of solar UV radiation in decreasing the durability of plastic materials, degradation of plastic debris, formation of micro- and nanoplastic particles and accompanying leaching of potential toxic compounds. Micro- and nanoplastics have been found in all ecosystems, the atmosphere, and in humans. While the potential biological risks are not yet well-established, the widespread and increasing occurrence of plastic pollution is reason for continuing research and monitoring. Plastic debris persists after its intended life in soils, water bodies and the atmosphere as well as in living organisms. To counteract accumulation of plastics in the environment, the lifetime of novel plastics or plastic alternatives should better match the functional life of products, with eventual breakdown releasing harmless substances to the environment.
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- 2023
83. Programa del Medio Ambiente de las Naciones Unidas (UNEP), Preguntas y Respuestas acerca de los Efectos de la Disminución del Ozono, la Radiación Ultravioleta y el Clima en los humanos y el Medio Ambiente. Suplemento del Reporte de Evaluación 2022 del Panel de Evaluación de los Efectos en el Medio Ambiente de las Naciones Unidas
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Sulbaek Andersen, Mads P, Andrady, Anthony L, Bais, Alkiviadis F, Barnes, Paul, Bernhard, Germar H, Byrne, Scott N, Heikkila, Anu M, Ireland, Rachael, Jansen, Marcel A. K, Madronich, Sasha, McKenzie, Richard L, Neale, Rachel, Neale, Patrick J, Ossola, Rachele, Wang, Qing-Wei, Wangberg, Sten-Ake, White, Christopher C, Wilson, Stephen R, Zepp, Richard G, Robinson, Sharon A, Sulbaek Andersen, Mads P, Andrady, Anthony L, Bais, Alkiviadis F, Barnes, Paul, Bernhard, Germar H, Byrne, Scott N, Heikkila, Anu M, Ireland, Rachael, Jansen, Marcel A. K, Madronich, Sasha, McKenzie, Richard L, Neale, Rachel, Neale, Patrick J, Ossola, Rachele, Wang, Qing-Wei, Wangberg, Sten-Ake, White, Christopher C, Wilson, Stephen R, Zepp, Richard G, and Robinson, Sharon A
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Esta colección de preguntas y respuestas fue preparada por el Panel de Evaluación de los Efectos en el Medio Ambiente (EEAP por sus siglas en inglés) del Protocolo de Montreal bajo el amparo del Programa para el Medio Ambiente de las Naciones Unidas (PNUM). Este documento es un complemento de la Evaluación Cuatrienal 2022 realizada por el EEAP (https://ozone. unep.org/science/assessment/eeap), y provee de información interesante y útil para redactores de políticas públicas, maestros y científicos. Este P&Rs está escrito en un lenguaje de fácil comprensión para el público en general.
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- 2023
84. Association between frontal plane knee control and lower extremity injuries: a prospective study on young team sport athletes
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Anu M Räisänen, Kati Pasanen, Tron Krosshaug, Tommi Vasankari, Pekka Kannus, Ari Heinonen, Urho M Kujala, Janne Avela, Jarmo Perttunen, and Jari Parkkari
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Medicine (General) ,R5-920 - Abstract
Background/aim Poor frontal plane knee control can manifest as increased dynamic knee valgus during athletic tasks. The purpose of this study was to investigate the association between frontal plane knee control and the risk of acute lower extremity injuries. In addition, we wanted to study if the single-leg squat (SLS) test can be used as a screening tool to identify athletes with an increased injury risk.Methods A total of 306 basketball and floorball players participated in the baseline SLS test and a 12-month injury registration follow-up. Acute lower extremity time-loss injuries were registered. Frontal plane knee projection angles (FPKPA) during the SLS were calculated using a two-dimensional video analysis.Results Athletes displaying a high FPKPA were 2.7 times more likely to sustain a lower extremity injury (adjusted OR 2.67, 95% CI 1.23 to 5.83) and 2.4 times more likely to sustain an ankle injury (OR 2.37, 95% CI 1.13 to 4.98). There was no statistically significant association between FPKPA and knee injury (OR 1.49, 95% CI 0.56 to 3.98). The receiver operating characteristic curve analyses indicated poor combined sensitivity and specificity when FPKPA was used as a screening test for lower extremity injuries (area under the curve of 0.59) and ankle injuries (area under the curve of 0.58).Conclusions Athletes displaying a large FPKPA in the SLS test had an elevated risk of acute lower extremity and ankle injuries. However, the SLS test is not sensitive and specific enough to be used as a screening tool for future injury risk.
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- 2018
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85. The increasing burden of diabetes and variations among the states of India: the Global Burden of Disease Study 1990–2016
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Nikhil Tandon, Ranjit M Anjana, Viswanathan Mohan, Tanvir Kaur, Ashkan Afshin, Kanyin Ong, Satinath Mukhopadhyay, Nihal Thomas, Eesh Bhatia, Anand Krishnan, Prashant Mathur, R S Dhaliwal, D K Shukla, Anil Bhansali, Dorairaj Prabhakaran, Paturi V Rao, Chittaranjan S Yajnik, G Anil Kumar, Chris M Varghese, Melissa Furtado, Sanjay K Agarwal, Megha Arora, Deeksha Bhardwaj, Joy K Chakma, Leslie Cornaby, Eliza Dutta, Scott Glenn, N Gopalakrishnan, Rajeev Gupta, Panniyammakal Jeemon, Sarah C Johnson, Tripti Khanna, Sanjay Kinra, Michael Kutz, Pallavi Muraleedharan, Nitish Naik, Chrisopher M Odell, Anu M Oommen, Jeyaraj D Pandian, Sreejith Parameswaran, Sanghamitra Pati, Narayan Prasad, D Sreebhushan Raju, Ambuj Roy, Meenakshi Sharma, Chander Shekhar, Sharvari R Shukla, Narinder P Singh, J S Thakur, Ranjit Unnikrishnan, Santosh Varughese, Denis Xavier, Geevar Zachariah, Stephen S Lim, Mohsen Naghavi, Rakhi Dandona, Theo Vos, Christopher J L Murray, K Srinath Reddy, Soumya Swaminathan, and Lalit Dandona
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Public aspects of medicine ,RA1-1270 - Abstract
Summary: Background: The burden of diabetes is increasing rapidly in India but a systematic understanding of its distribution and time trends is not available for every state of India. We present a comprehensive analysis of the time trends and heterogeneity in the distribution of diabetes burden across all states of India between 1990 and 2016. Methods: We analysed the prevalence and disability-adjusted life-years (DALYs) of diabetes in the states of India from 1990 to 2016 using all available data sources that could be accessed as part of the Global Burden of Diseases, Injuries, and Risk Factors Study 2016, and assessed heterogeneity across the states. The states were placed in four groups based on epidemiological transition level (ETL), defined on the basis of the ratio of DALYs from communicable diseases to those from non-communicable diseases and injuries combined, with a low ratio denoting high ETL and vice versa. We assessed the contribution of risk factors to diabetes DALYs and the relation of overweight (body-mass index 25 kg/m2 or more) with diabetes prevalence. We calculated 95% uncertainty intervals (UIs) for the point estimates. Findings: The number of people with diabetes in India increased from 26·0 million (95% UI 23·4–28·6) in 1990 to 65·0 million (58·7–71·1) in 2016. The prevalence of diabetes in adults aged 20 years or older in India increased from 5·5% (4·9–6·1) in 1990 to 7·7% (6·9–8·4) in 2016. The prevalence in 2016 was highest in Tamil Nadu and Kerala (high ETL) and Delhi (higher-middle ETL), followed by Punjab and Goa (high ETL) and Karnataka (higher-middle ETL). The age-standardised DALY rate for diabetes increased in India by 39·6% (32·1–46·7) from 1990 to 2016, which was the highest increase among major non-communicable diseases. The age-standardised diabetes prevalence and DALYs increased in every state, with the percentage increase among the highest in several states in the low and lower-middle ETL state groups. The most important risk factor for diabetes in India was overweight to which 36·0% (22·6–49·2) of the diabetes DALYs in 2016 could be attributed. The prevalence of overweight in adults in India increased from 9·0% (8·7–9·3) in 1990 to 20·4% (19·9–20·8) in 2016; this prevalence increased in every state of the country. For every 100 overweight adults aged 20 years or older in India, there were 38 adults (34–42) with diabetes, compared with the global average of 19 adults (17–21) in 2016. Interpretation: The increase in health loss from diabetes since 1990 in India is the highest among major non-communicable diseases. With this increase observed in every state of the country, and the relative rate of increase highest in several less developed low ETL states, policy action that takes these state-level differences into account is needed urgently to control this potentially explosive public health situation. Funding: Bill & Melinda Gates Foundation; and Indian Council of Medical Research, Department of Health Research, Ministry of Health and Family Welfare, Government of India.
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- 2018
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86. The changing patterns of cardiovascular diseases and their risk factors in the states of India: the Global Burden of Disease Study 1990–2016
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Dorairaj Prabhakaran, Panniyammakal Jeemon, Meenakshi Sharma, Gregory A Roth, Catherine Johnson, Sivadasanpillai Harikrishnan, Rajeev Gupta, Jeyaraj D Pandian, Nitish Naik, Ambuj Roy, R S Dhaliwal, Denis Xavier, Raman K Kumar, Nikhil Tandon, Prashant Mathur, D K Shukla, Ravi Mehrotra, K Venugopal, G Anil Kumar, Chris M Varghese, Melissa Furtado, Pallavi Muraleedharan, Rizwan S Abdulkader, Tahiya Alam, Ranjit M Anjana, Monika Arora, Anil Bhansali, Deeksha Bhardwaj, Eesh Bhatia, Joy K Chakma, Pankaj Chaturvedi, Eliza Dutta, Scott Glenn, Prakash C Gupta, Sarah C Johnson, Tanvir Kaur, Sanjay Kinra, Anand Krishnan, Michael Kutz, Manu R Mathur, Viswanathan Mohan, Satinath Mukhopadhyay, Minh Nguyen, Christopher M Odell, Anu M Oommen, Sanghamitra Pati, Martin Pletcher, Kameshwar Prasad, Paturi V Rao, Chander Shekhar, Dhirendra N Sinha, P N Sylaja, J S Thakur, Kavumpurathu R Thankappan, Nihal Thomas, Simon Yadgir, Chittaranjan S Yajnik, Geevar Zachariah, Ben Zipkin, Stephen S Lim, Mohsen Naghavi, Rakhi Dandona, Theo Vos, Christopher J L Murray, K Srinath Reddy, Soumya Swaminathan, and Lalit Dandona
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Public aspects of medicine ,RA1-1270 - Abstract
Summary: Background: The burden of cardiovascular diseases is increasing in India, but a systematic understanding of its distribution and time trends across all the states is not readily available. In this report, we present a detailed analysis of how the patterns of cardiovascular diseases and major risk factors have changed across the states of India between 1990 and 2016. Methods: We analysed the prevalence and disability-adjusted life-years (DALYs) due to cardiovascular diseases and the major component causes in the states of India from 1990 to 2016, using all accessible data sources as part of the Global Burden of Diseases, Injuries, and Risk Factors Study 2016. We placed states into four groups based on epidemiological transition level (ETL), defined using the ratio of DALYs from communicable diseases to those from non-communicable diseases and injuries combined, with a low ratio denoting high ETL and vice versa. We assessed heterogeneity in the burden of major cardiovascular diseases across the states of India, and the contribution of risk factors to cardiovascular diseases. We calculated 95% uncertainty intervals (UIs) for the point estimates. Findings: Overall, cardiovascular diseases contributed 28·1% (95% UI 26·5–29·1) of the total deaths and 14·1% (12·9–15·3) of the total DALYs in India in 2016, compared with 15·2% (13·7–16·2) and 6·9% (6·3–7·4), respectively, in 1990. In 2016, there was a nine times difference between states in the DALY rate for ischaemic heart disease, a six times difference for stroke, and a four times difference for rheumatic heart disease. 23·8 million (95% UI 22·6–25·0) prevalent cases of ischaemic heart disease were estimated in India in 2016, and 6·5 million (6·3–6·8) prevalent cases of stroke, a 2·3 times increase in both disorders from 1990. The age-standardised prevalence of both ischaemic heart disease and stroke increased in all ETL state groups between 1990 and 2016, whereas that of rheumatic heart disease decreased; the increase for ischaemic heart disease was highest in the low ETL state group. 53·4% (95% UI 52·6–54·6) of crude deaths due to cardiovascular diseases in India in 2016 were among people younger than 70 years, with a higher proportion in the low ETL state group. The leading overlapping risk factors for cardiovascular diseases in 2016 included dietary risks (56·4% [95% CI 48·5–63·9] of cardiovascular disease DALYs), high systolic blood pressure (54·6% [49·0–59·8]), air pollution (31·1% [29·0–33·4]), high total cholesterol (29·4% [24·3–34·8]), tobacco use (18·9% [16·6–21·3]), high fasting plasma glucose (16·7% [11·4–23·5]), and high body-mass index (14·7% [8·3–22·0]). The prevalence of high systolic blood pressure, high total cholesterol, and high fasting plasma glucose increased generally across all ETL state groups from 1990 to 2016, but this increase was variable across the states; the prevalence of smoking decreased during this period in all ETL state groups. Interpretation: The burden from the leading cardiovascular diseases in India—ischaemic heart disease and stroke—varies widely between the states. Their increasing prevalence and that of several major risk factors in every part of India, especially the highest increase in the prevalence of ischaemic heart disease in the less developed low ETL states, indicates the need for urgent policy and health system response appropriate for the situation in each state. Funding: Bill & Melinda Gates Foundation; and Indian Council of Medical Research, Department of Health Research, Ministry of Health and Family Welfare, Government of India.
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- 2018
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87. Up front and open, shrouded in secrecy, or somewhere in between? A Meta Research Systematic Review of Open Science Practices in Sport Medicine Research
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Garrett S. Bullock, Patrick Ward, Franco M. Impellizzeri, Stefan Kluzek, Tom Hughes, Charles Hillman, Brian R. Waterman, Kerry Danelson, Kaitlin Henry, Emily Barr, Kelsey Healey, Anu M. Räisänen, Christina Gomez, Garrett Fernandez, Jakob Wolf, Kristen F. Nicholson, Tim Sell, Ryan Zerega, Paula Dhiman, Richard D. Riley, and Gary S Collins
- Abstract
ObjectiveTo investigate the extent and qualitatively synthesize open science practices within research published in the top five sports medicine journals from 01 May 2022 and 01 October 2022.DesignMeta-research systematic reviewData SourcesMEDLINEEligibility CriteriaStudies were included if they were published in one of the identified top five sports medicine journals as ranked by Clarivate. Studies were excluded if they were systematic reviews, qualitative research, grey literature, or animal or cadaver models.Results243 studies were included. The median number of open science practices met per study was 2, out of a maximum of 12 (Range: 0-8; IQR: 2). 234 studies (96%, 95% CI: 94-99) provided an author conflict of interest statement and 163 (67%, 95% CI: 62-73) reported funding. 21 studies (9%, 95% CI: 5-12) provided open access data. 54 studies (22%, 95% CI: 17-included a data availability statement and 3 (1%, 95% CI: 0-3) made code available. 76 studies (32%, 95% CI: 25-37) had transparent materials and 30 (12%, 95% CI: 8-16) included a reporting guideline. 28 studies (12%, 95% CI: 8-16) were pre-registered. 6 studies (3%, 95% CI: 1-4) published a protocol. 4 studies (2%, 95% CI: 0-3) reported the availability of an analysis plan. 7 studies (3%, 95% CI: 1-5) reported patient and public involvement.ConclusionSports medicine open science practices are extremely limited. The least followed practices were sharing code, data, and analysis plans. Without implementing open practices, barriers concerning the ability to aggregate findings and create cumulative science will continue to exist.What is already knownOpen science practices provide a mechanism for evaluating and improving the quality and reproducibility of research in a transparent manner, thereby enhancing the benefits to patient outcomes and society at large.Understanding the current open science practices in sport medicine research can assist in identifying where and how sports medicine leadership can raise awareness, and develop strategies for improvement.What are the new findingsNo study published in the top five sports medicine journals met all open science practicesStudies often only met a small number of open science practicesOpen science practices that were least met included providing open access code, data sharing, and the availability of an analysis plan.
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- 2023
88. Raman Spectroscopic Studies on Graphene Oxide – Europium Nano Composites
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Anu M a, Dhanya I, Heera S, Rinta Prakash, and Nikhila Abraham
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Graphene based nano composites are receiving much importance in recent years due to the two-dimensional topology, high carrier mobility, luminescent nature, and ultra wide band gap transition. Here graphene oxide is prepared by modified Hammers method. Resultant residue of dark yellow color is filtered using Watt man No. 1 filter paper and is further cleaned by washing several times with 5% HCl solution and de-ionized water. Unexfoliated oxide is eliminated from the sample by ultra-sonication procedure for 30 minutes followed by micro-centrifugation under 4000 rpm for another 30 minutes. Vacuum annealing is done at sample at 60OC for 12 hours to get black graphene oxide powder and is labelled as Sample4. Europium (III) nitrate is added to 3g each of graphene oxide powder in 0.1g, 0.2g, and 0.3g concentration respectively labelled as Sample1, Sample2, and Sample3. Uniform mixing is done in composite samples. Morphological properties are analyzed through SEM. Surface topology of GO is like thin folded sheet, while that of Eu-GO is like that of spreading small nano materials on folded surface. Average particle size distribution is found to be 79.09 nm. Chemical composition and stotiometric ratio of different elements in the composites are quantitatively shown by EDX analysis. Raman spectra for Samples 1, 3, and 4 are shown. We can see that no shifting of peaks are observed in composites with respect to pure GO is an evidence of stable sp2 hybridisation and rigid oxygenated functional groups.
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- 2022
89. Electrochemical evaluation of cobalt oxide incorporated MoS2ex/PANI ternary composite as a promising electrode for high-performance symmetric and asymmetric supercapacitors
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Tomy, Merin, Anu, M. A., and Xavier, T. S.
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Graphical Abstract:
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- 2024
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90. Evaluating a Wearable Solution for Measuring Lower Extremity Asymmetry During Landing.
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Räisänen, Anu M., Benson, Lauren C., Whittaker, Jackie L., and Emery, Carolyn A.
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LEG physiology ,CONFIDENCE intervals ,FUNCTIONAL status ,WEARABLE technology ,BODY movement ,DESCRIPTIVE statistics ,JUMPING ,TIBIA ,STATISTICAL sampling ,DATA analysis software ,KINEMATICS - Abstract
Copyright of Physiotherapy Canada is the property of University of Toronto Press and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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- 2023
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91. The long-term burden of anterior cruciate ligament and meniscal injury: A systematic review and meta-analysis
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Filbay, Stephanie, primary, Whittaker, Jackie L., additional, Skou, Søren Thorgaard, additional, Toomey, Clodagh, additional, Räisänen, Anu M, additional, Ezzat, Allison, additional, Le, Christina Y., additional, and Crossley, Kay, additional
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- 2023
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92. SPICY: a method for single scan rotating frame relaxometry
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Tolkkinen, Katja, primary, Mailhiot, Sarah E., additional, Selent, Anne, additional, Mankinen, Otto, additional, Henschel, Henning, additional, Nieminen, Miika T., additional, Hanni, Matti, additional, Kantola, Anu M., additional, Liimatainen, Timo, additional, and Telkki, Ville-Veikko, additional
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- 2023
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93. Knee Extensor and Flexor Muscle Power Explains Stair Ascension Time in Patients With Unilateral Late-Stage Knee Osteoarthritis: A Cross-Sectional Study
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Valtonen, Anu M., Pöyhönen, Tapani, Manninen, Mikko, Heinonen, Ari, and Sipilä, Sarianna
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- 2015
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94. The 'SHRed Injuries Basketball' Neuromuscular Training Warm-up Program Reduces Ankle and Knee Injury Rates by 36% in Youth Basketball
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Carolyn A. Emery, Oluwatoyosi B.A. Owoeye, Anu M. Räisänen, Kimberley Befus, Tate Hubkarao, Luz Palacios-Derflingher, and Kati Pasanen
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Male ,Adolescent ,Athletic Injuries ,Sprains and Strains ,Humans ,Female ,Physical Therapy, Sports Therapy and Rehabilitation ,Basketball ,Knee Injuries ,General Medicine ,Ankle - Abstract
To evaluate the effectiveness of a neuromuscular training warm-up prevention program, Surveillance in High school and community sport to Reduce (SHRed) Injuries Basketball, for reducing all-complaint ankle and knee injuries in youth basketball players.Quasi-experimental study.High school/club basketball teams (male and female players aged 11-18 years) in Calgary, Canada participated in 2016-2017 (control; season 1) and 2017-2018 (intervention; season 2). The control season included a standard-of-practice warm-up. In season 2, a SHRed Injuries Basketball coach workshop was completed by participating team coaches. Teams were randomized by school/club to an unsupervised or a supervised (weekly supervision by study personnel) implementation of the coach-delivered SHRed Injuries Basketball program. The 10-minute SHRed Injuries Basketball program included 13 exercises (ie, aerobic, agility, strength, balance). All-complaint ankle and knee injuries were collected weekly using validated injury surveillance. Multilevel, multivariable Poisson regression analyses (considering important covariates, clustering by team and individual, and offset by exposure hours) estimated incidence rate ratios (IRRs) by intervention group (season 1 versus season 2) and secondarily considered the control versus completion of the SHRed Injuries Basketball program, unsupervised and supervised.Sixty-three teams (n = 502 players) participated in season 1 and 31 teams (n = 307 players: 143 unsupervised, 164 supervised) participated in season 2. The SHRed Injuries Basketball program was protective against all-complaint knee and ankle injuries (IRR = 0.64; 95% confidence interval [CI]: 0.51, 0.79). Unsupervised (IRR = 0.62; 95% CI: 0.47, 0.83) and supervised (IRR = 0.64; 95% CI: 0.49, 0.85) implementations of the SHRed Injuries Basketball program had similar protective effects.The SHRed Injuries Basketball program was associated with a 36% lower rate of ankle and knee injuries. Neuromuscular training warm-ups are recommended as the minimal standard of practice for injury prevention in youth basketball.
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- 2022
95. Insights into the role of molar ratio and added water in the properties of choline chloride and urea-based eutectic mixtures and their cellulose swelling capacity
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Juho Antti Sirviö, Riikka Haataja, Anu M. Kantola, Terhi Suopajärvi, and Henrikki Liimatainen
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Urea ,Water ,General Physics and Astronomy ,Hydrogen Bonding ,Physical and Theoretical Chemistry ,Cellulose ,Choline - Abstract
Eutectic mixtures and deep eutectic solvents (DESs) are promising green media for the pre-treatment of lignocellulose materials. They can be harnessed for the swelling of cellulose and further facilitate cellulose hydrolysis, derivatization, and production of cellulose-based (nano) materials. Several studies indicated that water can take part in the formation of the nanostructure of DES; however, it is still unclear how additional water influences many important properties and functioning of DES, especially when the molar ratio of compounds differs from the eutectic point composition. Here, viscosity, pH, conductivity, solvatochromic and solvatomagnetic solvent parameters, and fiber swelling capacity of choline chloride and urea mixtures demonstrating different molar ratios were investigated in the presence and absence of added water. The participation of water in the formation of molecular clusters with choline chloride and urea was indicated by viscosity, pH, and conductivity measurements. Hydrogen bond acceptor values of aqueous mixtures increased as a function of water content, and the results obtained using both methods were in line, indicating their suitability for the determination of hydrogen bond acidity of aqueous choline chloride–urea mixtures. However, hydrogen bond basicity determined by solvatochromic and magnetic methods exhibited almost opposite trends. The close investigation of the chemical shift of solvatomagnetic probes indicated that the chemical environment of the choline chloride–urea (1 : 2) mixture remained constant until the water content of 30 wt% was in line with previous molecular simulations. When cellulose fibers were treated with mixtures under mixing, the non-ideality of the choline chloride–urea mixture and the absence of water were found to be advantageous; however, aqueous mixtures efficiently increased the diameters of cellulose fibers in the absence of mixing, and water-containing mixtures appeared to be appealing systems for cellulose pretreatments.
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- 2022
96. OPTIKNEE 2022: consensus recommendations to optimise knee health after traumatic knee injury to prevent osteoarthritis
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Whittaker, Jackie L, primary, Culvenor, Adam G, additional, Juhl, Carsten Bogh, additional, Berg, Bjørnar, additional, Bricca, Alessio, additional, Filbay, Stephanie Rose, additional, Holm, Pætur, additional, Macri, Erin, additional, Urhausen, Anouk P, additional, Ardern, Clare L, additional, Bruder, Andrea M, additional, Bullock, Garrett S, additional, Ezzat, Allison M, additional, Girdwood, Michael, additional, Haberfield, Melissa, additional, Hughes, Mick, additional, Ingelsrud, Lina Holm, additional, Khan, Karim M, additional, Le, Christina Y, additional, Losciale, Justin M, additional, Lundberg, Matilde, additional, Miciak, Maxi, additional, Øiestad, Britt Elin, additional, Patterson, Brooke, additional, Räisänen, Anu M, additional, Skou, Søren T, additional, Thorlund, Jonas Bloch, additional, Toomey, Clodagh, additional, Truong, Linda K, additional, Meer, Belle L. van, additional, West, Thomas James, additional, Young, James Justin, additional, Lohmander, L Stefan, additional, Emery, Carolyn, additional, Risberg, May Arna, additional, van Middelkoop, Marienke, additional, Roos, Ewa M, additional, and Crossley, Kay M, additional
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- 2022
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97. The long-term burden of anterior cruciate ligament and meniscal injury: A systematic review and meta-analysis
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Stephanie Filbay, Jackie L. Whittaker, Søren Thorgaard Skou, Clodagh Toomey, Anu M Räisänen, Allison Ezzat, Christina Y. Le, and Kay Crossley
- Abstract
The primary objective of this systematic review is to determine the long-term burden of anterior cruciate ligament andmeniscal injury. The secondary objective is to determine the burden of living with radiographic and/orsymptomatic osteoarthritis, following anterior cruciate ligament and/or meniscal injury.
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- 2023
98. Decreased soil microbial nitrogen under vegetation 'shrubification' in the subarctic forest–tundra ecotone : the potential role of increasing nutrient competition between plants and soil microorganisms
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Sari Stark, Manoj Kumar, Eero Myrsky, Jere Vuorinen, Anu M. Kantola, Ville-Veikko Telkki, Sofie Sjögersten, Johan Olofsson, and Minna K. Männistö
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tundra heath ,Ekologi ,mountain birch forest ,Ecology ,Empetrum hermaphroditum ,soil organic matter ,Environmental Chemistry ,extracellular enzymes ,CO2 release ,Ecology, Evolution, Behavior and Systematics ,climate warming - Abstract
The consequences of warming-induced ‘shrubification’ on Arctic soil carbon storage are receiving increased attention, as the majority of ecosystem carbon in these systems is stored in soils. Soil carbon cycles in these ecosystems are usually tightly coupled with nitrogen availability. Soil microbial responses to ‘shrubification’ may depend on the traits of the shrub species that increase in response to warming. Increase in deciduous shrubs such as Betula nana likely promotes a loss of soil carbon, whereas the opposite may be true if evergreen shrubs such as Empetrum hermaphroditum increase. We analyzed soil organic matter stocks and 13C NMR fractions, microbial CO2 respiration, biomass, extracellular enzyme activities (EEAs), and their association with shrub density in northern Sweden after 20 years of experimental warming using open top chambers (OTCs). Our study sites were located in a tundra heath that stores high soil carbon quantities and where the OTCs had increased deciduous shrubs, and in a mountain birch forest that stores lower soil carbon quantities and where the OTCs had increased evergreen shrubs. We predicted that organic matter stocks should be lower and respiration and EEAs higher inside the OTCs than untreated plots in the tundra, whereas no effect should be detected in the forest. Soil organic matter stocks and 13C NMR fractions remained unaffected at both sites. When expressed as per gram microbial biomass, respiration and EEAs for carbohydrate and chitin degradation were higher inside the OTCs, and contrasting our prediction, this effect was stronger in the forest. Unexpectedly, the OTCs also led to a substantially lower microbial biomass carbon and nitrogen irrespective of habitat. The decline in the microbial biomass counteracted increased activities resulting in no effect of the OTCs on respiration and a lower phenol oxidase activity per gram soil. Microbial biomass nitrogen correlated negatively with evergreen shrub density at both sites, indicating that ‘shrubification’ may have intensified nutrient competition between plants and soil microorganisms. Nutrient limitation could also underlie increased respiration per gram microbial biomass through limiting C assimilation into biomass. We hypothesize that increasing nutrient immobilization into long-lived evergreen shrubs could over time induce microbial nutrient limitation that contributes to a stability of accumulated soil organic matter stocks under climate warming.
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- 2023
99. Encapsulation of xenon by bridged resorcinarene cages with high 129Xe NMR chemical shift and efficient exchange dynamics
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Sanna Komulainen, P. U. Ashvin Iresh Fernando, Jiří Mareš, Anne Selent, Roya Khalili, Paul T. Cesana, Andreas Ebeling, Anu M. Kantola, Ngong Kodiah Beyeh, Kari Rissanen, Brenton DeBoef, Perttu Lantto, and Ville-Veikko Telkki
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General Engineering ,General Physics and Astronomy ,ksenon ,General Chemistry ,biosensors ,laskennallinen kemia ,biosensorit ,aliphatically bridged resorcinarenes ,molecular dynamic simulations ,General Energy ,129Xe HyperCEST MRI ,supramolekulaarinen kemia ,piperazine-bridged resorcinarenes ,General Materials Science ,molekyylidynamiikka ,129Xe NMR ,supermolecules ,first principal modeling ,functionalized cages - Abstract
Functionalized cages encapsulating xenon atoms enable highly sensitive, background-free molecular imaging through a technique known as HyperCEST 129Xe MRI. Here, we introduce a class of potential biosensor cage structures based on two resorcinarene macrocycles bridged either by aliphatic carbon chains or piperazines. First-principles-based modeling predicts a high chemical shift (about 345 ppm) outside the typical experimental observation window for 129Xe encapsulated by the aliphatically bridged cage and two 129Xe resonances for the piperazine-bridged cages corresponding to single and double loading. Based on the computational predictions as well as 129Xe chemical exchange saturation transfer (CEST) and T2 relaxation nuclear magnetic resonance experiments, we confirm Xe encapsulation in the aliphatically bridged and double encapsulation in the piperazine-bridged resorcinarene in methanol. The cages show fast Xe exchange rates (12,000–49,000 s−1), resulting in a high CEST response regardless of the relatively low binding constant (0.09–3 M−1). peerReviewed
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- 2023
100. SPICY:a method for single scan rotating frame relaxometry
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Katja Tolkkinen, Sarah E. Mailhiot, Anne Selent, Otto Mankinen, Henning Henschel, Miika T. Nieminen, Matti Hanni, Anu M. Kantola, Timo Liimatainen, and Ville-Veikko Telkki
- Subjects
Fysikalisk kemi ,Atom and Molecular Physics and Optics ,General Physics and Astronomy ,Atom- och molekylfysik och optik ,Radiologi och bildbehandling ,Physical and Theoretical Chemistry ,Physical Chemistry ,Radiology, Nuclear Medicine and Medical Imaging - Abstract
T1ρ is an NMR relaxation mode that is sensitive to low frequency molecular motions, making it an especially valuable tool in biomolecular research. Here, we introduce a new method, SPICY, for measuring T1ρ relaxation times. In contrast to conventional T1ρ experiments, in which the sequence is repeated many times to determine the T1ρ time, the SPICY sequence allows determination of T1ρ within a single scan, shortening the experiment time remarkably. We demonstrate the method using ¹H T1ρ relaxation dispersion experiments. Additionally, we combine the sequence with spatial encoding to produce 1D images in a single scan. We show that T1ρ relaxation times obtained using the single scan approach are in good agreement with those obtained using the traditional experiments.
- Published
- 2023
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