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405 results on '"Basu, Soumyava"'

52. Mixed B- and T-lymphocyte Vitreous Infiltrate in Multiple Sclerosis Associated Uveitis.

Author

Khalid, Shabtab, Sharma, Gunjan, Jakati, Saumya, and Basu, Soumyava

Subjects
MULTIPLE sclerosis, UVEITIS, PARS plana, T cells, B cells
Abstract

A 23-year-old man, under treatment for relapsing remitting multiple sclerosis, presented with sudden drop in vision in the left eye for the past 1 week. We noted optic atrophy with sclerosed vessels in multiple quadrants in both eyes, moderate vitreous haze, and active retinal vasculitis in left eye. The patient received therapeutic pars plana vitrectomy in the left eye, and the vitreous sample was analyzed for immunophenotypes by flow cytometry (T-cells) and immunohistochemistry (B-cells). 65.1% of total vitreous cells were CD3+ T-cells. These included 42.4% CD4+, and 20.6% CD8+ T-cells. Immunohistochemistry detected CD20+ B-cells (not quantifiable). Our analysis demonstrated a mixed B- and T-lymphocyte vitreous infiltrate in multiple sclerosis-associated uveitis. [ABSTRACT FROM AUTHOR]

Published
2023
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53. DNA chip-assisted diagnosis of a previously unknown etiology of intermediate uveitis- Toxoplasma gondii

Author

Basu Soumyava, Sharma Savitri, Kar Sarita, and Das Taraprasad

Subjects
Intermediate uveitis, Toxoplasma gondii, polymerase chain reaction, Ophthalmology, RE1-994
Abstract

We report the use of DNA chip technology in the identification of Toxoplasma gondii as the etiological agent in two patients with recurrent intermediate uveitis (IU). Both patients had recurrent episodes of vitritis (with no focal retinochoroidal lesion) over varying time intervals and were diagnosed to have IU. The tuberculin test was negative in both. Blood counts, erythrocyte sedimentation rate, and serum angiotensin convertase enzyme levels were normal. In both cases, the vitreous fluid tested positive for the T. gondii DNA sequence by using a uveitis DNA chip (XCyton Pvt. Ltd., Bangalore, India). It contained complimentary sequences to "signature genes" of T. gondii, Mycobacterium tuberculosis, M. chelonae, and M. fortuitum. The enzyme-linked immunosorbent assay (ELISA) detected elevated serum antitoxoplasma IgG levels in both. They responded to the antitoxoplasma therapy with oral co-trimoxazole (and additional intravitreal clindamycin in patient 1), with no recurrence during follow-ups of 6 and 8 months, respectively.

Published
2010

54. Patterns of Non-Infectious Scleritis across a Tertiary Eye Care Network Using the Indigenously Developed Electronic Medical Record System-eyeSmart.

Author

Murthy, Somasheila I, Das, Anthony Vipin, Kammari, Priyanka, Roy, Aravind, Basu, Soumyava, Fernandes, Merle, Rathi, Varsha M, and Tyagi, Mudit

Subjects
ELECTRONIC health records, EYE care, SCLERITIS, TERTIARY care
Abstract

To report the pattern of noninfectious scleritis across a tertiary eye-care network. A three-year retrospective review of patients diagnosed with noninfectious scleritis was performed. Data were retrieved using diagnostic terms assigned to scleritis through the in-house eyeSmart-electronic medical record system. 1103 patients, with a mean age of 44.33 ± 14.38 years and a median follow-up of 199.5 days (range 32–685) were enrolled. Unilateral disease was noted in 85%. Diffuse anterior scleritis (n = 542, 42.51%) and nodular scleritis (n = 482, 38.12%) were the commonest subtypes. Systemic immune disease association was present in 65 (5.89%). Treatment at onset was topical corticosteroids (n = 372, 36.54%) followed by oral non-steroidal anti-inflammatory drugs (n = 351, 34.45%), oral corticosteroids in 184 (19.04%), and immunomodulators in 32 patients (3.54%). This study depicts the pattern of various noninfectious scleritis in a large cohort of patients. The present study helped to further customize the electronic medical records to minimize several data capture limitations. [ABSTRACT FROM AUTHOR]

Published
2022
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56. Vogt Koyanagi Harada Disease In Paediatric Age Group: Clinical Characteristics, Remission, Recurrences and Complications in Asian Indian Population

Author

Kaza, Hrishikesh, primary, Tyagi, Mudit, additional, Agarwal, Komal, additional, Behera, Shashwat, additional, Pappuru, Rajeev R, additional, Mohan, Sashwanthi, additional, Saldanha, Merlin, additional, Videkar, Chetan, additional, Basu, Soumyava, additional, Pathengay, Avinash, additional, and Murthy, Somasheila, additional

Published
2021
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60. Punctate Inner Retinal Toxoplasmosis: Case Series and Review of Literature.

Author

Kelgaonkar, Anup, Khalsa, Ashish, Padhy, Srikanta Kumar, Behera, Umesh Chandra, Padhi, Tapas Ranjan, and Basu, Soumyava

Abstract

To describe clinical and multimodal imaging characteristics of punctate inner retinal toxoplasmosis (PIRT) as an atypical presentation of ocular toxoplasmosis (OT). Retrospective review of OT cases with PIRT lesions and review of the literature. We describe five cases (6 eyes). PIRT lesions were seen adjacent to active/healed toxoplasma retinochoroiditis. The appearance of PIRT was creamy yellowish-white, inner retinal, punctate, and sub-centimetric lesions. The depth of these lesions on optical coherence tomography was till the outer plexiform layer. Co-existing punctate outer retinal toxoplasmosis (PORT) was found in three eyes and recurrent retinochoroiditis in three. The fate of PIRT was resolution with minimal retinal thinning or progression to a full-thickness retinochoroiditis. PIRT was noted in association with typical toxoplasma retinochoroiditis and PORT lesions, and had equal chances of resolution or progression to full-thickness lesions. [ABSTRACT FROM AUTHOR]

Published
2022
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65. Collaborative Ocular Tuberculosis Study Consensus Guidelines on the Management of Tubercular Uveitis—Report 1

Author

Agrawal, Rupesh, primary, Testi, Ilaria, additional, Mahajan, Sarakshi, additional, Yuen, Yew Sen, additional, Agarwal, Aniruddha, additional, Kon, Onn Min, additional, Barisani-Asenbauer, Talin, additional, Kempen, John H., additional, Gupta, Amod, additional, Jabs, Douglas A., additional, Smith, Justine R., additional, Nguyen, Quan Dong, additional, Pavesio, Carlos, additional, Gupta, Vishali, additional, Agarwal, Mamta, additional, Agarwal, Manisha, additional, Aggarwal, Ashutosh, additional, Aggarwal, Kanika, additional, Agrawal, Mukesh, additional, Al-Dhibi, Hassan, additional, Androudi, Sofia, additional, Asyari, Fatma, additional, Balasundaram, Manohar Babu, additional, Murthy, Kalpana Babu, additional, Baglivo, Edoardo, additional, Banker, Alay, additional, Bansal, Reema, additional, Basu, Soumyava, additional, Behera, Digamber, additional, Biswas, Jyotirmay, additional, Bodaghi, Bahram, additional, Carreño, Ester, additional, Caspers, Laure, additional, Chee, Soon Phaik, additional, Chhabra, Romi, additional, Cimino, Luca, additional, Concha del Rio, Luz Elena, additional, Cunningham, Emmett T., additional, Land Curi, Andrè Luiz, additional, Das, Dipankar, additional, Davis, Janet, additional, DeSmet, Marc, additional, Denisova, Ekaterina, additional, Denniston, Alastair K., additional, Errera, Marie-Hélène, additional, Fonollosa, Alejandro, additional, George, Amala, additional, Goldstein, Debra A., additional, Crosier, Yan Guex, additional, Gunasekeran, Dinesh Visva, additional, Gurbaxani, Avinash, additional, Invernizzi, Alessandro, additional, Isa, Hazlita M., additional, Islam, Shah Md., additional, Jones, Nicholas, additional, Katoch, Deeksha, additional, Khairallah, Moncef, additional, Khosla, Amit, additional, Kramer, Michal, additional, Kumar, Amitabh, additional, Kumar, Atul, additional, La Distia Nora, Rina, additional, Lee, Richard, additional, Lowder, Careen, additional, Luthra, Saurabh, additional, Mahendradas, Padmamalini, additional, Makhoul, Dorine, additional, Mazumdar, Shahana, additional, McCluskey, Peter, additional, Mehta, Salil, additional, Miserocchi, Elisabetta, additional, Mochizuki, Manabu, additional, Mohamed, Oli S., additional, Muccioli, Cristina, additional, Munk, Marion R., additional, Murthy, Somasheila, additional, Narain, Shishir, additional, Nascimento, Heloisa, additional, Neri, Piergiorgio, additional, Nguyen, Myhanh, additional, Okada, Annabelle A., additional, Ozdal, Pinar, additional, Palestine, Alan, additional, Pichi, Francesco, additional, Raje, Dhananjay, additional, Rathinam, S.R., additional, Rousselot, Andres, additional, Schlaen, Ariel, additional, Sehgal, Shobha, additional, Sen, H. Nida, additional, Sharma, Aman, additional, Sharma, Kusum, additional, Shoughy, Samir S., additional, Singh, Nirbhai, additional, Singh, Ramandeep, additional, Soheilian, Masoud, additional, Sridharan, Sudharshan, additional, Thorne, Jennifer E., additional, Tappeiner, Christoph, additional, Teoh, Stephen, additional, Tognon, Maria Sofia, additional, Tugal-Tutkun, Ilknur, additional, Tyagi, Mudit, additional, Uy, Harvey, additional, Vasconcelos Santos, Daniel Vitor, additional, Valentincic, Natasa Vidovic, additional, Westcott, Mark, additional, Yanai, Ryoji, additional, Alvarez, Bety Yanez, additional, Zahedur, Rahman, additional, and Zierhut, Manfred, additional

Published
2021
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66. Collaborative Ocular Tuberculosis Study Consensus Guidelines on the Management of Tubercular Uveitis—Report 2

Author

Agrawal, Rupesh, primary, Testi, Ilaria, additional, Bodaghi, Baharam, additional, Barisani-Asenbauer, Talin, additional, McCluskey, Peter, additional, Agarwal, Aniruddha, additional, Kempen, John H., additional, Gupta, Amod, additional, Smith, Justine R., additional, de Smet, Marc D., additional, Yuen, Yew Sen, additional, Mahajan, Sarakshi, additional, Kon, Onn Min, additional, Nguyen, Quan Dong, additional, Pavesio, Carlos, additional, Gupta, Vishali, additional, Agrawal, Rupesh, additional, Agarwal, Mamta, additional, Agarwal, Manisha, additional, Aggarwal, Ashutosh, additional, Aggarwal, Kanika, additional, Agrawal, Mukesh, additional, Al-Dhibi, Hassan, additional, Androudi, Sofia, additional, Asyari, Fatma, additional, Balasundaram, Manohar Babu, additional, Murthy, Kalpana Babu, additional, Baglivo, Edoardo, additional, Banker, Alay, additional, Bansal, Reema, additional, Basu, Soumyava, additional, Behera, Digamber, additional, Biswas, Jyotirmay, additional, Carreño, Ester, additional, Caspers, Laure, additional, Chee, Soon Phaik, additional, Chhabra, Romi, additional, Cimino, Luca, additional, Concha del Rio, Luz Elena, additional, Cunningham, Emmett T., additional, Land Curi, Andrè Luiz, additional, Das, Dipankar, additional, Davis, Janet, additional, DeSmet, Marc, additional, Denisova, Ekaterina, additional, Denniston, Alastair K., additional, Errera, Marie-Hélène, additional, Fonollosa, Alejandro, additional, George, Amala, additional, Goldstein, Debra A., additional, Crosier, Yan Guex, additional, Gunasekeran, Dinesh Visva, additional, Gurbaxani, Avinash, additional, Invernizzi, Alessandro, additional, Isa, Hazlita M., additional, Islam, Shah M.d., additional, Jones, Nicholas, additional, Katoch, Deeksha, additional, Khairallah, Moncef, additional, Khosla, Amit, additional, Kramer, Michal, additional, Kumar, Amitabh, additional, Kumar, Atul, additional, La Distia Nora, Rina, additional, Lee, Richard, additional, Lowder, Careen, additional, Luthra, Saurabh, additional, Mahendradas, Padmamalini, additional, Makhoul, Dorine, additional, Mazumdar, Shahana, additional, Mehta, Salil, additional, Miserocchi, Elisabetta, additional, Mochizuki, Manabu, additional, Mohamed, Oli S., additional, Muccioli, Cristina, additional, Munk, Marion R., additional, Murthy, Somasheila, additional, Narain, Shishir, additional, Nascimento, Heloisa, additional, Neri, Piergiorgio, additional, Nguyen, Myhanh, additional, Okada, Annabelle A., additional, Ozdal, Pinar, additional, Palestine, Alan, additional, Pichi, Francesco, additional, Raje, Dhananjay, additional, Rathinam, S.R., additional, Rousselot, Andres, additional, Schlaen, Ariel, additional, Sehgal, Shobha, additional, Nida Sen, H., additional, Sharma, Aman, additional, Sharma, Kusum, additional, Shoughy, Samir S., additional, Singh, Nirbhai, additional, Singh, Ramandeep, additional, Soheilian, Masoud, additional, Sridharan, Sudharshan, additional, Thorne, Jennifer E., additional, Tappeiner, Christoph, additional, Teoh, Stephen, additional, Tognon, Maria Sofia, additional, Tugal-Tutkun, Ilknur, additional, Tyagi, Mudit, additional, Uy, Harvey, additional, Vasconcelos Santos, Daniel Vitor, additional, Valentincic, Natasa Vidovic, additional, Westcott, Mark, additional, Yanai, Ryoji, additional, Alvarez, Bety Yanez, additional, Zahedur, Rahman, additional, Zierhut, Manfred, additional, and Xian, Zheng, additional

Published
2021
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73. Contributors

Author

Abtahi, Maryam, Adams, Wendy, Afshari, Natalie A., Agarwal, Anita, Agranat, Joshua S., Ajlan, Radwan S., Akhlaq, Anam, Al-Aswad, Lama, AlBayyat, Ghada, Albini, Thomas A., Ghoul, Ahmed Al, Al-Mohtaseb, Zaina, Alvi, Nishat P., Apple, David J., Aquino, Maria Cecilia, Arnold, Anthony C., Arnoldi, Kyle, Arshinoff, Steve A., Asbell, Penny A., Ashe, Stephen A., Asroui, Lara, Atebara, Neal H., Awh, Katherine C., Aylward, G. William, Bacci, Tommaso, Bakri, Sophie J., Balcer, Laura J., Balducci, Nicole, Barboni, Piero, Baş, Zeynep, Basu, Soumyava, Baumal, Caroline R., Bessette, Angela P., Bhatt, Nirali, Bhullar, Paramjit K., Binotti, William, Birch, Eileen E., Biswas, Jyotirmay, Bjerregaard, Robert William, Bose, Swaraj, Bouchard, Charles S., Boulton, Michael E., Bouremel, Yann, Brandt, James D., Brocchini, Steve, Brodie, Scott E., Brodsky, Michael C., Brooks, Cassandra, Brown, Aaron Christopher, Budenz, Donald L., Cantor, Louis B., Capo, Hilda, Capone, Antonio, Jr., Carruthers, Alastair, Carruthers, Jean D., Carter, Keith D., Chahal, Harinderpal, Chan, Chi-Chao, Chan, Jane W., Chang, Melinda Y., Chang, Stanley, Charteris, David G., Chee, Soon-Phaik, Chen, Masako, Chen, Michael Yipeng, Chen, Sien, Chen, Xuejing, Tec Kuan Chew, Paul, Chong, Jillian K., Chow, Clement C., Clarke, Jonathan C.K., Codère, François, Conner, Ian P., Soledad Cortina, Maria, Couch, Steven M., Coupland, Stuart G., Cowan, Claude, Craven, E. Randy, Cukras, Catherine A., Dagi, Linda, Dalvin, Lauren A., Damgaard, Iben Bach, Fatehali Damji, Karim, Das, Dipankar, DeBusk, Adam, Carlo, Talisa E. de, Coulon, Sara Jacob, Demer, Joseph Louis, Desai, Shilpa J., Dhaliwal, Deepinder K., Dhawlikar, Nisha, Diamond, Gary R., Diaz, Jose Daniel, Diniz, Daniel, Djenderedjian, Levon, Do, Anna Thanh Tam, Do, Diana V., Dolman, Peter J., Donahue, Sean P., Drenser, Kimberly A., Duffy, Kevin R., Duker, Jacob S., Duker, Jay S., Dupps, William J., Jr., Durairaj, Vikram D., Dutton, Jonathan J., Eliott, Dean, Engelbert, Michael, Enzor, Rikki S., Epstein, Aliza, Evans, Joshua W., Evans, Monica, Faia, Lisa J., Fallano, Katherine A., Farjo, Ayad A., Fernandez, Karen B., Fisher, Yale L., Fortun, Jorge A., Friedman, Deborah I., Friedman, Neil J., Fynn-Thompson, Nicoletta, Gadaria-Rathod, Neha, Garg, Sumit (Sam), Gayre, Gregg, Gedde, Steven, Geevarghese, Alexi, Ghosh, Saurabh, William Gigantelli, James, Goerlitz-Jessen, Mark, Goldberg, Ivan, Goldberg, Jeffrey L., Goldstein, Debra A., Goldstein, Michael H., Gonzales, John A., Gore, Charlotte, Granet, David B., Greven, Craig M., Greven, Margaret A., Gross, Ronald L., Gündüz, Ahmet Kaan, Gupta, Preeya K., Haller, Julia A., Hamrah, Pedram, Hannush, Sadeer B., Hardin, Joshua S., Harris, Alon, Hassan, Muhammad, Heier, Jeffrey S., Herndon, Leon W., Ho, Allen C., Ho, Joanne W., Honasoge, Avinash, Hood, Christopher T., Houghton, Odette, Houser, Kourtney, Howes, Frank W., Hsu, Jason, Hurwitz, Jeffrey J., Irochima, Francisco, Isteitiya, Jihad, Iyer, Geetha, Izak, Andrea M., Jackson, Kevin, Jacob, Soosan, Jacoba, Cris Martin P., Jacobs, Deborah S., Jampel, Henry D., Jampol, Lee M., Jeng-Miller, Karen, Jing-Wei Chen, John, Johnson, Mark W., Johnson, T. Mark, Johnstone, Murray, Kaakour, Abdul-Hadi, Kaehr, Mark M., Kahook, Malik Y., Kaiser, Peter K., Kalafatis, Nicholas, Kalevar, Ananda, Kane, Steven, Kang, Kai, Kanner, Elliott M., Kapoor, Saloni, Alton Kapusta, Michael, Karanjia, Rustum, Kardon, Randy H., Karp, Carol L., Kashani, Amir H., Kass, Michael A., Kataguiri, Paula, Kaufman, Paul L., D. Keenan, Jeremy, Kelly, Elaine, Kenyon, Kenneth R., Khandelwal, Sumitra, Tee Khaw, Peng, Kim, Ivana K., Kim, Terry, Kinori, Michael, Kiss, Szilárd, Kitchens, John W., Klein, Kendra, Ko, Narae, Koch, Douglas D., Kodati, Shilpa, Koh, Victor, Kohnen, Thomas, Konstas, Angelos A., Koo, Ellen, Lane, Stephen S., Lavin, Patrick J.M., Lavinsky, Fabio, Lawton, Andrew W., Le, Nhon T., Lee, Bonny, Lee, Crystal, Lee, Gregory D., Lee, Paul P, Han Lee, Rachel, Ann Lim, Dawn Ka, Lin, Tony, Lind, John T., Liu, Dan, Liu, Yao, Liyanage, Sidath E., Longmuir, Reid A., Lundström, Mats, N. Maamari, Robi, Mahjoub, Heba, Maloney, Maya H., Mamalis, Christina, Manche, Edward E., Mandava, Naresh, Martheswaran, Tanisha, Masket, Samuel, Mattox, Cynthia, Kevin McClatchey, Scott, McLeod, Stephen D., McMillan, Brian D., McNab, Alan A., Mehra, Ankur, Mehta, Jodhbir S., Mejia-Vergara, Alvaro J., Mejico, Luis J., Mekhail, Joseph, N. Mercer, Ryan, Mian, Shahzad I., Mieler, William F., Miller, Kyle E., Mirza, Rukhsana G., Misra, Poonam, Mititelu, Mihai, Mohammed, Taariq, Moorthy, Ramana S., Morkin, Melina I., Moshfeghi, Andrew A., Moshirfar, Majid, Moss, Heather E., Moster, Mark L., Muhtaseb, Ruba, Muir, Kelly W., Neff, Ann G., Nerad, Jeffrey A., Ng, Caleb C., Nguyen, Annie, Nikpoor, Neda, Nosé, Ricardo, Okada, Annabelle A., Datoo O'Keefe, Ghazala A., Olson, Jeffrey L., Olver, Jane M., Örge, Faruk H., Packard, Richard, Packer, Mark, Panarelli, Joseph, Pandey, Suresh K., Parikh, Vishal S., Pasha, Hamza, Pasquale, Louis R., Patel, Palak, Patel, Sarju S., Patel, Shaila R., Patel, Vivek R., Pavesio, Carlos, Perez, Victor L., Phillips, Lauren T., Piltz-Seymour, Jody R., Piva, Alfio P., Presland, Andrew H., Price, Francis W., Price, Marianne O., Quiros, Peter A., Rachitskaya, Aleksandra, Rahmani, Safa, Ramulu, Pradeep Y., Randleman, J. Bradley, Rao, Narsing A., Rao, Naveen K., Rao, P. Kumar, Rao, Rajesh C., Rathinam, Sivakumar, Read, Russell W., Reed, Donovan, Vinícius Saito Regatieri, Caio, Regillo, Carl D., Reichel, Elias, Reighard, Chelsea L., Richard, Alyse, Ringeisen, Alexander, Ritch, Robert, Robbins, Shira L., M. Rocha, Karolinne, Rodger, Damien C., Roh, Miin, Rosado-Adames, Noel, Rowe, Lucas W., Rubenstein, Jonathan B., Rubin, Richard M., Rubsamen, Patrick E., Saadati, Hossein G., Sadun, Alfredo A., Saeedi, Osamah, Sajjad, Ahmar, Salchow, Daniel J., Salim, Sarwat, Salongcay, Recivall P., Sandhu, Simrenjeet, Santhiago, Marcony R., Satija, Celine E., M. Schallhorn, Julie, Schmitt, Melanie, Schor, Paulo, Schroeder, Richard, Schubert, Hermann D., Schuman, Joel S., Schwartz, Gary S., Sen, H. Nida, Shah, Gaurav K., Shah, Ravi, Shields, Carol L., Shields, Jerry A., Shildkrot, Yevgeniy (Eugene), Shingleton, Bradford J., Shtein, Roni M., Shu-Wen Chan, Nicole, Shultz, Ryan W., Sieck, Erin, Siesky, Brent, Sieving, Paul A., S. Silva, Paolo, Simmons, Kirsten, Skondra, Dimitra, Smiddy, William E., Somogyi, Marie, Soong, H. Kaz, Soukiasian, Sarkis H., Spoor, Thomas C., Srinivasan, Bhaskar, Srivastava, Sunil K., Starnes, Taylor W., Starr, Matthew R., Steel, David H., Steigleman, W. Allan, Stein, Joshua D., Stepien, Kimberly E., Stevens, Dylan V., Strominger, Mitchell B., Sugar, Alan, Sugar, Joel, Suh, Donny W., Sun, Michelle, Sun, Yang, Sychev, Yevgeniy V., Tai, Tania, Tan, James C., Tanenbaum, Myron, Tasman, William, Tassignon, Marie-José B., Testi, Ilaria, Thall, Edmond H., Thanos, Aristomenis, Theophanous, Christos N., Thornton, Sarah, Tingey, David P., Todorich, Bozho, Tompson, Stuart W., Toy, Brian, Tsai, James C., Tsai, Julie, Tucker, Nancy, Tuli, Sonal S., Valerio, Gabriel S., Vargason, Caroline W., Vasaiwala, Roshni A., Vitor Vasconcelos-Santos, Daniel, Vaughn, Gregory J., Venkateswaran, Nandini, Vinod, Kateki, Vislisel, Jesse M., Vrcek, Ivan, Walton, David S., Wang, Li, Wang, Michelle Y., Wang, Robert C., Waring IV, George O., Weikert, Mitchell P., Werner, Liliana, Wevill, Mark, Wiggs, Janey L., Williams, Andrew M., Williams, George A., Witmer, Matthew T., Wollstein, Gadi, Woodward, Maria A., Wride, Nicholas K., Wu, Albert Y., Yaghy, Antonio, Young, Joshua A., Zaguia, Fatma, Zein, Wadih M., and Zhu, Ivy

Published
2023
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79. Diagnostic Markers in Ocular Sarcoidosis in A High TB Endemic Population – A Multicentre Study

Author

Babu, Kalpana, primary, Biswas, Jyotirmay, additional, Agarwal, Manisha, additional, Mahendradas, Padmamalini, additional, Bansal, Reema, additional, Rathinam, S.R., additional, Basu, Soumyava, additional, Ganesh, Sudha K, additional, Konana, Vinaya Kumar, additional, Vedhanayaki, Rajesh, additional, Philips, Mariamma, additional, and Choudhary, Tripti, additional

Published
2020
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84. The Collaborative Ocular Tuberculosis Study (COTS) Consensus (CON) Group Meeting Proceedings

Author

Agrawal, Rupesh, primary, Testi, Ilaria, additional, Mahajan, Sarakshi, additional, Yuen, Yew Sen, additional, Agarwal, Aniruddha, additional, Rousselot, Andres, additional, Raje, Dhananjay, additional, Gunasekeran, Dinesh Visva, additional, Kon, Onn Min, additional, Barisani-Asenbauer, Talin, additional, Kempen, John H., additional, Gupta, Amod, additional, Jabs, Douglas A., additional, Smith, Justine R., additional, Bodaghi, Bahram, additional, Zierhut, Manfred, additional, DeSmet, Marc, additional, Cluskey, Peter Mc, additional, Agarwal, Mamta, additional, Agarwal, Manisha, additional, Aggarwal, Kanika, additional, Agrawal, Mukesh, additional, Al-Dhibi, Hassan, additional, Androudi, Sofia, additional, Asyari, Fatma, additional, Balasundaram, Manohar Babu, additional, Murthy, Kalpana Babu, additional, Baglivo, Edoardo, additional, Banker, Alay, additional, Bansal, Reema, additional, Basu, Soumyava, additional, Behera, Digamber, additional, Biswas, Jyotirmay, additional, Carreño, Ester, additional, Caspers, Laure, additional, Chee, Soon Phaik, additional, Chhabra, Romi, additional, Cimino, Luca, additional, del Rio, Luz Elena Concha, additional, Cunningham, Emmett T., additional, Curi, Andrè Luiz Land, additional, Das, Dipankar, additional, Denisova, Ekaterina, additional, Denniston, Alastair K, additional, Errera, Marie-Hélène, additional, Fonollosa, Alejandro, additional, George, Amala, additional, Goldstein, Debra A., additional, Crosier, Yan Guex, additional, Gurbaxani, Avinash, additional, Invernizzi, Alessandro, additional, Isa, Hazlita M., additional, Md. Islam, Shah, additional, Jones, Nicholas, additional, Katoch, Deeksha, additional, Khairallah, Moncef, additional, Khosla, Amit, additional, Kramer, Michal, additional, Kumar, Amitabh, additional, Kumar, Atul, additional, Nora, Rina La Distia, additional, Lee, Richard, additional, Lowder, Careen, additional, Luthra, Saurabh, additional, Mahendradas, Padmamalini, additional, Makhoul, Dorine, additional, Mazumdar, Shahana, additional, Mehta, Salil, additional, Miserocchi, Elisabetta, additional, Mochizuki, Manabu, additional, Mohamed, Oli S., additional, Muccioli, Cristina, additional, Munk, Marion R, additional, Murthy, Somasheila, additional, Narain, Shishir, additional, Nascimento, Heloisa, additional, Neri, Piergiorgio, additional, Nguyen, Myhanh, additional, Okada, Annabelle A., additional, Ozdal, Pinar, additional, Palestine, Alan, additional, Pichi, Francesco, additional, Rathinam, S.R, additional, Schlaen, Ariel, additional, Sehgal, Shobha, additional, Sen, H Nida, additional, Sharma, Aman, additional, Sharma, Kusum, additional, Shoughy, Samir S., additional, Singh, Nirbhai, additional, Singh, Ramandeep, additional, Soheilian, Masoud, additional, Sridharan, Sudharshan, additional, Thorne, Jennifer E., additional, Tappeiner, Christoph, additional, Teoh, Stephen, additional, Tognon, Maria Sofia, additional, Tugal-Tutkun, Ilknur, additional, Tyagi, Mudit, additional, Uy, Harvey, additional, Santos, Daniel Vitor Vasconcelos, additional, Valentincic, Natasa Vidovic, additional, Westcott, Mark, additional, Yanai, Ryoji, additional, Alvarez, Bety Yanez, additional, Zahedur, Rahman, additional, Nguyen, Quan Dong, additional, Pavesio, Carlos, additional, and Gupta, Vishali, additional

Published
2020
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88. Diagnostic Markers in Ocular Sarcoidosis in A High TB Endemic Population – A Multicentre Study.

Author

Babu, Kalpana, Biswas, Jyotirmay, Agarwal, Manisha, Mahendradas, Padmamalini, Bansal, Reema, Rathinam, S.R., Basu, Soumyava, Ganesh, Sudha K, Konana, Vinaya Kumar, Vedhanayaki, Rajesh, Philips, Mariamma, and Choudhary, Tripti

Abstract

To look at markers to differentiate ocular sarcoidosis from ocular tuberculosis in a high TB endemic population. Retrospective multicenter study involving seven tertiary eyecare centers in India between July 2016 to December 2016. Demographic, clinical and laboratory data were retrieved from respective hospital databases. Group A included biopsy-proven ocular sarcoidosis while group B included ocular tuberculosis. Data from 2726 consecutive patients with uveitis were retrieved from the databases. Group A had 61 cases while group B included 307 cases. The mean age in group A was 43 ± 16.55 years while in group B was 38 ± 13.13 years. Females were more common in group A. Uveitis with low Schirmer test (OR-30, CI-95%), candlewax retinal vasculitis (OR-8.69, CI-95%), hilar lymphadenopathy (OR-15.23, CI-95%), fissural nodules (OR-39.11, CI-95%) had higher odds of having ocular sarcoidosis. Presence of dry eye, candlewax retinal vasculitis, hilar lymphadenopathy, and fissural nodules if present in a patient with uveitis, could help differentiate ocular sarcoidosis from ocular tuberculosis in a high TB endemic population. [ABSTRACT FROM AUTHOR]

Published
2022
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89. Pattern of Recurrent Inflammation following Anti-tubercular Therapy for Ocular Tuberculosis.

Author

Multani, Prabhjot Kaur, Modi, Rohit, and Basu, Soumyava

Subjects
TUBERCULOSIS diagnosis, DRUG therapy for tuberculosis, INFLAMMATION, RETROSPECTIVE studies, UVEITIS, ANTITUBERCULAR agents
Abstract

Purpose: To investigate recurrence patterns following anti-tubercular therapy (ATT) in different anatomical presentations of ocular tuberculosis (OTB).Methods: Retrospective analysis of clinically diagnosed OTB patients divided anatomically into groups A (anterior + intermediate uveitis) and B (posterior + panuveitis). Recurrence was defined as reappearance of intraocular inflammation in a quiescent eye following completion of at least 6-months ATT. Anatomical sites of recurrence were compared to that of presentation.Results: No significant difference in post-ATT recurrent inflammation was noted between groups A (14.29%, 4/28) and B (8.59%,11/128) (p = .57). Mean follow up was 13.13 ± 14.67 months. All group A recurrences were in the same anatomical segment, whereas in group B, 41.7% (5/11) recurrences were in group A sites. Overall, the group A:B ratio was significantly higher during recurrent inflammation (8:7) than at presentation (28:128) (p < .0001, z-score).Conclusion: Anterior and intermediate uveitis, though uncommon at presentation, are relatively more common during post-ATT recurrences in OTB. [ABSTRACT FROM AUTHOR]

Published
2022
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90. Animal Models of Ocular Tuberculosis: Implications for Diagnosis and Treatment.

Author

Basu, Soumyava, Rao, Narsing, and Elkington, Paul

Subjects
*TUBERCULOSIS, *ANIMAL models in research, *DIAGNOSIS, *THERAPEUTICS, *IMMUNE response
Abstract

The pathogenesis of ocular tuberculosis (TB) has remained unclear due to the challenges of performing mechanistic studies on clinical samples. Animal models have the potential to bridge these gaps by providing information about ocular dissemination and localization of mycobacteria, innate and adaptive immune response, and granuloma formation in the eye. Here, we critically review various animal models of ocular TB from the early 20th century to date and derive novel insights into pathogenesis of ocular TB that have direct implications on the diagnosis and treatment of this disease. Future directions on experimental approaches to understanding pathogenesis of ocular TB are also discussed. [ABSTRACT FROM AUTHOR]

Published
2021
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91. Inflammatory mediators in diabetic retinopathy: Deriving clinicopathological correlations for potential targeted therapy.

Author

Sheemar, Abhishek, Soni, Deepak, Takkar, Brijesh, Basu, Soumyava, and Venkatesh, Pradeep

Subjects
INFLAMMATORY mediators, DIABETIC retinopathy, CLINICAL pathology, GROWTH factors, SYMPTOMS, CHEMOKINES
Abstract

The role of inflammation in diabetic retinopathy (DR) is well-established and dysregulation of a large number of inflammatory mediators is known. These include cytokines, chemokines, growth factors, mediators of proteogenesis, and pro-apoptotic molecules. This para-inflammation as a response is not directed to a particular pathogen or antigen but is rather directed toward the by-products of the diabetic milieu. The inflammatory mediators take part in cascades that result in cellular level responses like neurodegeneration, pericyte loss, leakage, capillary drop out, neovascularization, etc. There are multiple overlaps between the inflammatory pathways occurring within the diabetic retina due to a large number of mediators, their varied sources, and cross-interactions. This makes understanding the role of inflammation in clinical manifestations of DR difficult. Currently, mediator-based therapy for DR is being evaluated for interventions that target a specific step of the inflammatory cascade. We reviewed the role of inflammation in DR and derived a simplified clinicopathological correlation between the sources and stimuli of inflammation, the inflammatory mediators and pathways, and the clinical manifestations of DR. By doing so, we deliberate mediator-specific therapy for DR. The cross-interactions between inflammatory mediators and the molecular cycles influencing the inflammatory cascades are crucial challenges to such an approach. Future research should be directed to assess the feasibility of the pathology-based therapy for DR. [ABSTRACT FROM AUTHOR]

Published
2021
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92. Imaging in tuberculosis-associated uveitis

Author

Bansal, Reema, Basu, Soumyava, Gupta, Amod, Rao, Narsing, Invernizzi, Alessandro, and Kramer, Michal

Subjects
Tuberculosis -- Diagnosis -- Care and treatment -- Complications and side effects -- Research, Uveitis -- Diagnosis -- Care and treatment -- Research, Health
Abstract

Byline: Reema. Bansal, Soumyava. Basu, Amod. Gupta, Narsing. Rao, Alessandro. Invernizzi, Michal. Kramer Intraocular tuberculosis (TB) can have several clinical presentations, affecting nearly every tissue of the eye. These clinical [...]

Published
2017

94. Sympathetic Ophthalmia after Vitreoretinal Surgeries: Incidence, Clinical Presentations and Outcomes of a Rare Disease

Author

Tyagi, Mudit, primary, Agarwal, Komal, additional, Reddy Pappuru, Rajeev R, additional, Dedhia, Chintan, additional, Agarwal, Hitesh, additional, Nayak, Sameera, additional, Panchal, Bhavik, additional, Kaza, Hrishikesh, additional, Basu, Soumyava, additional, Pathengay, Avinash, additional, Murthy, Somasheila, additional, and Sangwan, Virender S, additional

Published
2019
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96. Reply

Author

Dave, Vivek Pravin, primary, Pathengay, Avinash, additional, Sharma, Savitri, additional, Naveen, Nuvula, additional, Basu, Soumyava, additional, Pappuru, Rajeev R., additional, and Das, Taraprasad, additional

Published
2019
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99. Diagnostic and Therapeutic Challenges

Author

Agarwal, Aniruddha, Marchese, Alessandro, Aggarwal, Kanika, Arora, Atul, Thattaruthody, Faisal, Sharma, Kusum, Sharma, Suryaprakash, Sharma, Aman, Gupta, Vishali, Basu, Soumyava, and McDonald, H. Richard

Published
2022
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