876 results on '"Blobel, Gerd A."'
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52. Pre-existing immunity does not impair the engraftment of electroporation-mediated RNP CRISPR-Cas9-edited cells in rhesus macaques conditioned with busulfan or radiation
53. Interspecies regulatory landscapes and elements revealed by novel joint systematic integration of human and mouse blood cell epigenomes
54. Cooperative Activities of Hematopoietic Regulators Recruit RNA Polymerase II to a Tissue-Specific Chromatin Domain
55. CREB-Binding Protein Cooperates with Transcription Factor GATA-1 and is Required for Erythroid Differentiation
56. Supplementary Data from Ubiquitin-Specific Protease 6 Functions as a Tumor Suppressor in Ewing Sarcoma through Immune Activation
57. Data from Ubiquitin-Specific Protease 6 Functions as a Tumor Suppressor in Ewing Sarcoma through Immune Activation
58. Gene silencing dynamics are modulated by transiently active regulatory elements
59. Allosteric autoregulation of DNA binding via a DNA-mimicking protein domain: a biophysical study of ZNF410–DNA interaction using small angle X-ray scattering
60. Forced enhancer-promoter rewiring to alter gene expression in animal models
61. A dynamic intron retention program in the mammalian megakaryocyte and erythrocyte lineages
62. Erythropoiesis provides a BRD's eye view of BET protein function
63. Functions of BET proteins in erythroid gene expression
64. Regulation of Fetal Hemoglobin Production in Adult Erythroid Cells By Protein Phosphatase 6C (PPP6C)
65. Mechanisms of Polycomb Group Protein-Mediated Fetal Hemoglobin Silencing
66. Examining the Role of Individual Baf Chromatin Remodeling Complex Components in Globin Gene Regulation
67. Let-7 Inhibits HIC2 to Control BCL11A Transcription and Hemoglobin Switching
68. The heme-regulated inhibitor kinase requires dimerization for heme-sensing activity
69. The type 2 diabetes presumed causal variant within TCF7L2 resides in an element that controls the expression of ACSL5
70. Long-range enhancer activity determines Myc sensitivity to Notch inhibitors in T cell leukemia
71. GWAS to Therapy by Genome Edits?
72. A genome-editing strategy to treat [beta]-hemoglobinopathies that recapitulates a mutation associated with a benign genetic condition
73. Analysis of disease-causing GATA1 mutations in murine gene complementation systems
74. Pluripotent stem cells reveal erythroid-specific activities of the GATA1 N-terminus
75. A comparative encyclopedia of DNA elements in the mouse genome
76. Targeting the EIF2AK1 Signaling Pathway Rescues Red Blood Cell Production in SF3B1 Mutant Myelodysplastic Syndromes With Ringed Sideroblasts
77. Detecting Long-Range Enhancer–Promoter Interactions by Quantitative Chromosome Conformation Capture
78. Bromodomain protein Brd3 associates with acetylated GATA1 to promote its chromatin occupancy at erythroid target genes
79. Circadian REV-ERBs repress E4bp4 to activate NAMPT-dependent NAD+ biosynthesis and sustain cardiac function
80. Protein Phosphatase 6C (PPP6C) Loss Significantly Raises Fetal Hemoglobin Levels and Reduces Cell Sickling
81. Regulation of Fetal Hemoglobin Expression By the VHL-HIF1α Oxygen Sensing System
82. Interrogating Post-Transcriptional Mechanisms of Fetal Hemoglobin Regulation
83. HIC2 Controls Developmental Hemoglobin Switching By Repressing BCL11A Transcription
84. Isolated Changes in Chromatin Accessibility and Enhancer-Promoter Contacts at the β-Globin Locus Distinguish Fetal Hemoglobin Producing F-Cells from a-Cells
85. CTCF blocks anti-sense transcription initiation at divergent gene promoters
86. FOG1 requires NuRD to promote hematopoiesis and maintain lineage fidelity within the megakaryocytic-erythroid compartment
87. ZMYND8-regulated IRF8 transcription axis is an acute myeloid leukemia dependency
88. Abstract LB205: The IRF8-MEF2D transcription factor circuit regulated by a druggable multiple post-translational modification (PTM) reader ZMYND8 in acute myeloid leukemia
89. SCL and associated proteins distinguish active from repressive GATA transcription factor complexes
90. The v-src Inducible Gene 9E3/pCEF4 is Regulated by Both Its Promoter Upstream Sequence and Its 3' Untranslated Region
91. Supplemental Material for Keller et al., 2021
92. Activating RNAs associate with mediator to enhance chromatin architecture and transcription
93. CTCF and transcription influence chromatin structure re-configuration after mitosis
94. Intrinsically disordered Meningioma-1 stabilizes the BAF complex to cause AML
95. Editorial overview: Breaking open the mysteries of nuclear and chromatin organization
96. Lnk constrains myeloproliferative diseases in mice
97. Effects of sheared chromatin length on ChIP-seq quality and sensitivity
98. Heterogeneity of fetal hemoglobin production in adult red blood cells
99. Ubiquitin-Specific Protease 6 Functions as a Tumor Suppressor in Ewing Sarcoma through Immune Activation
100. Distinct properties and functions of CTCF revealed by a rapidly inducible degron system
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