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53. Multidrug-Resistant and Virulent Organisms Trauma Infections: Trauma Infectious Disease Outcomes Study Initiative

Author

Mende, Katrin, Akers, Kevin S, Tyner, Stuart D, Bennett, Jason W, Simons, Mark P, Blyth, Dana M, Li, Ping, Stewart, Laveta, and Tribble, David R

Subjects
TIDOS Supplement, Bacteria, Public Health, Environmental and Occupational Health, Bacterial Infections, Microbial Sensitivity Tests, General Medicine, Hospitals, Military, Communicable Diseases, United States, Anti-Bacterial Agents, Drug Resistance, Multiple, Bacterial, Gram-Negative Bacteria, Escherichia coli, Wound Infection, Humans, Enterococcus
Abstract

Introduction During the wars in Iraq and Afghanistan, increased incidence of multidrug-resistant (MDR) organisms, as well as polymicrobial wounds and infections, complicated the management of combat trauma–related infections. Multidrug resistance and wound microbiology are a research focus of the Trauma Infectious Disease Outcomes Study (TIDOS), an Infectious Disease Clinical Research Program, Uniformed Services University, research protocol. To conduct comprehensive microbiological research with the goal of improving the understanding of the complicated etiology of wound infections, the TIDOS MDR and Virulent Organisms Trauma Infections Initiative (MDR/VO Initiative) was established as a collaborative effort with the Brooke Army Medical Center, Naval Medical Research Center, U.S. Army Institute of Surgical Research, and Walter Reed Army Institute of Research. We provide a review of the TIDOS MDR/VO Initiative and summarize published findings. Methods Antagonism and biofilm formation of commonly isolated wound bacteria (e.g., ESKAPE pathogens—Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter spp.), antimicrobial susceptibility patterns, and clinical outcomes are being examined. Isolates collected from admission surveillance swabs, as part of infection control policy, and clinical infection workups were retained in the TIDOS Microbiological Repository and associated clinical data in the TIDOS database. Results Over the TIDOS study period (June 2009 to December 2014), more than 8,300 colonizing and infecting isolates were collected from military personnel injured with nearly one-third of isolates classified as MDR. At admission to participating U.S. military hospitals, 12% of wounded warriors were colonized with MDR Gram-negative bacilli. Furthermore, 27% of 913 combat casualties with ≥1 infection during their trauma hospitalization had MDR Gram-negative bacterial infections. Among 335 confirmed combat-related extremity wound infections (2009–2012), 61% were polymicrobial and comprised various combinations of Gram-negative and Gram-positive bacteria, yeast, fungi, and anaerobes. Escherichia coli was the most common Gram-negative bacilli isolated from clinical workups, as well as the most common colonizing MDR secondary to extended-spectrum β-lactamase resistance. Assessment of 479 E. coli isolates collected from wounded warriors found 188 pulsed-field types (PFTs) from colonizing isolates and 54 PFTs from infecting isolates without significant overlap across combat theaters, military hospitals, and study years. A minority of patients with colonizing E. coli isolates developed subsequent infections with the same E. coli strain. Enterococcus spp. were most commonly isolated from polymicrobial wound infections (53% of 204 polymicrobial cultures). Patients with Enterococcus infections were severely injured with a high proportion of lower extremity amputations and genitourinary injuries. Approximately 65% of polymicrobial Enterococcus infections had other ESKAPE organisms isolated. As biofilms have been suggested as a cause of delayed wound healing, wound infections with persistent recovery of bacteria (isolates of same organism collected ≥14 days apart) and nonrecurrent bacterial isolates were assessed. Biofilm production was significantly associated with recurrent bacteria isolation (97% vs. 59% with nonrecurrent isolates; P Conclusions The TIDOS MDR/VO Initiative provides comprehensive and detailed data of major microbial threats associated with combat-related wound infections to further the understanding of wound etiology and potentially identify infectious disease countermeasures, which may lead to improvements in combat casualty care.

Published
2022

56. Hydro-PE: gridded datasets of historical and future Penman-Monteith potential evaporation for the United Kingdom

Author

Robinson, Emma L., Brown, Matthew J., Kay, Alison L., Lane, Rosanna A., Chapman, Rhian, Bell, Victoria A., Blyth, Eleanor M., Robinson, Emma L., Brown, Matthew J., Kay, Alison L., Lane, Rosanna A., Chapman, Rhian, Bell, Victoria A., and Blyth, Eleanor M.

Abstract

We present two new potential evaporation datasets for the United Kingdom: a historical dataset, Hydro-PE HadUK-Grid, which is derived from the HadUK-Grid gridded observed meteorology (1969–2021), and a future dataset, Hydro-PE UKCP18 RCM, which is derived from UKCP18 regional climate projections (1980–2080). Both datasets are suitable for hydrological modelling and provide Penman–Monteith potential evapotranspiration parameterised for short grass, with and without a correction for interception on days with rainfall. The potential evapotranspiration calculations have been formulated to closely follow the methodology of the existing Meteorological Office Rainfall and Evaporation Calculation System (MORECS) potential evapotranspiration, which has historically been widely used by hydrological modellers in the United Kingdom. The two datasets have been created using the same methodology to allow seamless modelling from past to future. Hydro-PE HadUK-Grid shows good agreement with MORECS in much of the United Kingdom, although Hydro-PE HadUK-Grid is higher in the mountainous regions of Scotland and Wales. This is due to differences in the underlying meteorology, in particular the wind speed, which are themselves due to the different spatial scales of the data. Hydro-PE HadUK-Grid can be downloaded from https://doi.org/10.5285/9275ab7e-6e93-42bc-8e72-59c98d409deb (Brown et al., 2022) and Hydro-PE UKCP18 RCM can be downloaded from https://doi.org/10.5285/eb5d9dc4-13bb-44c7-9bf8-c5980fcf52a4 (Robinson et al., 2021).

Published
2023

57. Global, regional, and national burden of low back pain, 1990–2020, its attributable risk factors, and projections to 2050:a systematic analysis of the Global Burden of Disease Study 2021

Author

Ferreira, Manuela L., de Luca, Katie, Haile, Lydia M., Steinmetz, Jaimie D., Culbreth, Garland T., Cross, Marita, Kopec, Jacek A., Ferreira, Paulo H., Blyth, Fiona M., Buchbinder, Rachelle, Hartvigsen, Jan, Wu, Ai Min, Safiri, Saeid, Woolf, Anthony D., Collins, Gary S., Ong, Kanyin Liane, Vollset, Stein Emil, Smith, Amanda E., Cruz, Jessica A., Fukutaki, Kai Glenn, Abate, Semagn Mekonnen, Abbasifard, Mitra, Abbasi-Kangevari, Mohsen, Abbasi-Kangevari, Zeinab, Abdelalim, Ahmed, Abedi, Aidin, Abidi, Hassan, Adnani, Qorinah Estiningtyas Sakilah, Ahmadi, Ali, Akinyemi, Rufus Olusola, Alamer, Abayneh Tadesse, Alem, Adugnaw Zeleke, Alimohamadi, Yousef, Alshehri, Mansour Abdullah, Alshehri, Mohammed Mansour, Alzahrani, Hosam, Amini, Saeed, Amiri, Sohrab, Amu, Hubert, Andrei, Catalina Liliana, Andrei, Tudorel, Antony, Benny, Arabloo, Jalal, Arulappan, Judie, Arumugam, Ashokan, Ashraf, Tahira, Athari, Seyyed Shamsadin, Awoke, Nefsu, Charalampous, Periklis, Yang, Lin, Ferreira, Manuela L., de Luca, Katie, Haile, Lydia M., Steinmetz, Jaimie D., Culbreth, Garland T., Cross, Marita, Kopec, Jacek A., Ferreira, Paulo H., Blyth, Fiona M., Buchbinder, Rachelle, Hartvigsen, Jan, Wu, Ai Min, Safiri, Saeid, Woolf, Anthony D., Collins, Gary S., Ong, Kanyin Liane, Vollset, Stein Emil, Smith, Amanda E., Cruz, Jessica A., Fukutaki, Kai Glenn, Abate, Semagn Mekonnen, Abbasifard, Mitra, Abbasi-Kangevari, Mohsen, Abbasi-Kangevari, Zeinab, Abdelalim, Ahmed, Abedi, Aidin, Abidi, Hassan, Adnani, Qorinah Estiningtyas Sakilah, Ahmadi, Ali, Akinyemi, Rufus Olusola, Alamer, Abayneh Tadesse, Alem, Adugnaw Zeleke, Alimohamadi, Yousef, Alshehri, Mansour Abdullah, Alshehri, Mohammed Mansour, Alzahrani, Hosam, Amini, Saeed, Amiri, Sohrab, Amu, Hubert, Andrei, Catalina Liliana, Andrei, Tudorel, Antony, Benny, Arabloo, Jalal, Arulappan, Judie, Arumugam, Ashokan, Ashraf, Tahira, Athari, Seyyed Shamsadin, Awoke, Nefsu, Charalampous, Periklis, and Yang, Lin

Abstract

Background: Low back pain is highly prevalent and the main cause of years lived with disability (YLDs). We present the most up-to-date global, regional, and national data on prevalence and YLDs for low back pain from the Global Burden of Diseases, Injuries, and Risk Factors Study 2021. Methods: Population-based studies from 1980 to 2019 identified in a systematic review, international surveys, US medical claims data, and dataset contributions by collaborators were used to estimate the prevalence and YLDs for low back pain from 1990 to 2020, for 204 countries and territories. Low back pain was defined as pain between the 12th ribs and the gluteal folds that lasted a day or more; input data using alternative definitions were adjusted in a network meta-regression analysis. Nested Bayesian meta-regression models were used to estimate prevalence and YLDs by age, sex, year, and location. Prevalence was projected to 2050 by running a regression on prevalence rates using Socio-demographic Index as a predictor, then multiplying them by projected population estimates. Findings: In 2020, low back pain affected 619 million (95% uncertainty interval 554–694) people globally, with a projection of 843 million (759–933) prevalent cases by 2050. In 2020, the global age-standardised rate of YLDs was 832 per 100 000 (578–1070). Between 1990 and 2020, age-standardised rates of prevalence and YLDs decreased by 10·4% (10·9–10·0) and 10·5% (11·1–10·0), respectively. A total of 38·8% (28·7–47·0) of YLDs were attributed to occupational factors, smoking, and high BMI. Interpretation: Low back pain remains the leading cause of YLDs globally, and in 2020, there were more than half a billion prevalent cases of low back pain worldwide. While age-standardised rates have decreased modestly over the past three decades, it is projected that globally in 2050, more than 800 million people will have low back pain. Challenges persist in obtaining primary country-level data on low back pain, and there

Published
2023

59. SUPPLEMENT : THE CONVECTIVE PRECIPITATION EXPERIMENT (COPE) Investigating the Origins of Heavy Precipitation in the Southwestern United Kingdom

Author

Leon, David C., French, Jeffrey R., Lasher-Trapp, Sonia, Blyth, Alan M., Abel, Steven J., Ballard, Susan, Bennett, Lindsay J., Bower, Keith, Brooks, Barbara, Brown, Phil, Choularton, Thomas, Clark, Peter, Collier, Chris, Crosier, Jonathan, Cui, Zhiqiang, Dufton, David, Eagle, Chloe, Flynn, Michael J., Gallagher, Martin, Hanley, Kirsty, Huang, Yahui, Kitchen, Malcolm, Korolev, Alexei, Lean, Humphrey, Liu, Zixia, Marsham, John, Moser, Daniel, Nicol, John, Norton, Emily G., Plummer, David, Price, Jeremy, Ricketts, Hugo, Roberts, Nigel, Taylor, Jonathan W., and Williams, Paul I.

Published
2016

60. THE CONVECTIVE PRECIPITATION EXPERIMENT (COPE) : Investigating the Origins of Heavy Precipitation in the Southwestern United Kingdom

Author

Leon, David C., French, Jeffrey R., Lasher-Trapp, Sonia, Blyth, Alan M., Abel, Steven J., Ballard, Susan, Barrett, Andrew, Bennett, Lindsay J., Bower, Keith, Brooks, Barbara, Brown, Phil, Charlton-Perez, Cristina, Choularton, Thomas, Clark, Peter, Collier, Chris, Crosier, Jonathan, Cui, Zhiqiang, Dey, Seonaid, Dufton, David, Eagle, Chloe, Flynn, Michael J., Gallagher, Martin, Halliwell, Carol, Hanley, Kirsty, Hawkness-Smith, Lee, Huang, Yahui, Kelly, Graeme, Kitchen, Malcolm, Korolev, Alexei, Lean, Humphrey, Liu, Zixia, Marsham, John, Moser, Daniel, Nicol, John, Norton, Emily G., Plummer, David, Price, Jeremy, Ricketts, Hugo, Roberts, Nigel, Rosenberg, Phil D., Simonin, David, Taylor, Jonathan W., Warren, Robert, Williams, Paul I., and Young, Gillian

Published
2016

63. Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks in 188 countries, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013

Author

Forouzanfar, Mohammad H, Alexander, Lily, Anderson, H Ross, Bachman, Victoria F, Biryukov, Stan, Brauer, Michael, Burnett, Richard, Casey, Daniel, Coates, Matthew M, Cohen, Aaron, Delwiche, Kristen, Estep, Kara, Frostad, Joseph J, KC, Astha, Kyu, Hmwe H, Moradi-Lakeh, Maziar, Ng, Marie, Slepak, Erica Leigh, Thomas, Bernadette A, Wagner, Joseph, Aasvang, Gunn Marit, Abbafati, Cristiana, Ozgoren, Ayse Abbasoglu, Abd-Allah, Foad, Abera, Semaw F, Aboyans, Victor, Abraham, Biju, Abraham, Jerry Puthenpurakal, Abubakar, Ibrahim, Abu-Rmeileh, Niveen M E, Aburto, Tania C, Achoki, Tom, Adelekan, Ademola, Adofo, Koranteng, Adou, Arsène K, Adsuar, José C, Afshin, Ashkan, Agardh, Emilie E, Al Khabouri, Mazin J, Al Lami, Faris H, Alam, Sayed Saidul, Alasfoor, Deena, Albittar, Mohammed I, Alegretti, Miguel A, Aleman, Alicia V, Alemu, Zewdie A, Alfonso-Cristancho, Rafael, Alhabib, Samia, Ali, Raghib, Ali, Mohammed K, Alla, François, Allebeck, Peter, Allen, Peter J, Alsharif, Ubai, Alvarez, Elena, Alvis-Guzman, Nelson, Amankwaa, Adansi A, Amare, Azmeraw T, Ameh, Emmanuel A, Ameli, Omid, Amini, Heresh, Ammar, Walid, Anderson, Benjamin O, Antonio, Carl Abelardo T, Anwari, Palwasha, Cunningham, Solveig Argeseanu, Arnlöv, Johan, Arsenijevic, Valentina S Arsic, Artaman, Al, Asghar, Rana J, Assadi, Reza, Atkins, Lydia S, Atkinson, Charles, Avila, Marco A, Awuah, Baffour, Badawi, Alaa, Bahit, Maria C, Bakfalouni, Talal, Balakrishnan, Kalpana, Balalla, Shivanthi, Balu, Ravi Kumar, Banerjee, Amitava, Barber, Ryan M, Barker-Collo, Suzanne L, Barquera, Simon, Barregard, Lars, Barrero, Lope H, Barrientos-Gutierrez, Tonatiuh, Basto-Abreu, Ana C, Basu, Arindam, Basu, Sanjay, Basulaiman, Mohammed O, Ruvalcaba, Carolina Batis, Beardsley, Justin, Bedi, Neeraj, Bekele, Tolesa, Bell, Michelle L, Benjet, Corina, Bennett, Derrick A, Benzian, Habib, Bernabé, Eduardo, Beyene, Tariku J, Bhala, Neeraj, Bhalla, Ashish, Bhutta, Zulfiqar A, Bikbov, Boris, Abdulhak, Aref A Bin, Blore, Jed D, Blyth, Fiona M, Bohensky, Megan A, Başara, Berrak Bora, Borges, Guilherme, Bornstein, Natan M, Bose, Dipan, Boufous, Soufiane, Bourne, Rupert R, Brainin, Michael, Brazinova, Alexandra, Breitborde, Nicholas J, Brenner, Hermann, Briggs, Adam D M, Broday, David M, Brooks, Peter M, Bruce, Nigel G, Brugha, Traolach S, Brunekreef, Bert, Buchbinder, Rachelle, Bui, Linh N, Bukhman, Gene, Bulloch, Andrew G, Burch, Michael, Burney, Peter G J, Campos-Nonato, Ismael R, Campuzano, Julio C, Cantoral, Alejandra J, Caravanos, Jack, Cárdenas, Rosario, Cardis, Elisabeth, Carpenter, David O, Caso, Valeria, Castañeda-Orjuela, Carlos A, Castro, Ruben E, Catalá-López, Ferrán, Cavalleri, Fiorella, Çavlin, Alanur, Chadha, Vineet K, Chang, Jung-chen, Charlson, Fiona J, Chen, Honglei, Chen, Wanqing, Chen, Zhengming, Chiang, Peggy P, Chimed-Ochir, Odgerel, Chowdhury, Rajiv, Christophi, Costas A, Chuang, Ting-Wu, Chugh, Sumeet S, Cirillo, Massimo, Claßen, Thomas KD, Colistro, Valentina, Colomar, Mercedes, Colquhoun, Samantha M, Contreras, Alejandra G, Cooper, Cyrus, Cooperrider, Kimberly, Cooper, Leslie T, Coresh, Josef, Courville, Karen J, Criqui, Michael H, Cuevas-Nasu, Lucia, Damsere-Derry, James, Danawi, Hadi, Dandona, Lalit, Dandona, Rakhi, Dargan, Paul I, Davis, Adrian, Davitoiu, Dragos V, Dayama, Anand, de Castro, E Filipa, De la Cruz-Góngora, Vanessa, De Leo, Diego, de Lima, Graça, Degenhardt, Louisa, del Pozo-Cruz, Borja, Dellavalle, Robert P, Deribe, Kebede, Derrett, Sarah, Jarlais, Don C Des, Dessalegn, Muluken, deVeber, Gabrielle A, Devries, Karen M, Dharmaratne, Samath D, Dherani, Mukesh K, Dicker, Daniel, Ding, Eric L, Dokova, Klara, Dorsey, E Ray, Driscoll, Tim R, Duan, Leilei, Durrani, Adnan M, Ebel, Beth E, Ellenbogen, Richard G, Elshrek, Yousef M, Endres, Matthias, Ermakov, Sergey P, Erskine, Holly E, Eshrati, Babak, Esteghamati, Alireza, Fahimi, Saman, Faraon, Emerito Jose A, Farzadfar, Farshad, Fay, Derek F J, Feigin, Valery L, Feigl, Andrea B, Fereshtehnejad, Seyed-Mohammad, Ferrari, Alize J, Ferri, Cleusa P, Flaxman, Abraham D, Fleming, Thomas D, Foigt, Nataliya, Foreman, Kyle J, Paleo, Urbano Fra, Franklin, Richard C, Gabbe, Belinda, Gaffikin, Lynne, Gakidou, Emmanuela, Gamkrelidze, Amiran, Gankpé, Fortuné G, Gansevoort, Ron T, García-Guerra, Francisco A, Gasana, Evariste, Geleijnse, Johanna M, Gessner, Bradford D, Gething, Pete, Gibney, Katherine B, Gillum, Richard F, Ginawi, Ibrahim A M, Giroud, Maurice, Giussani, Giorgia, Goenka, Shifalika, Goginashvili, Ketevan, Dantes, Hector Gomez, Gona, Philimon, de Cosio, Teresita Gonzalez, González-Castell, Dinorah, Gotay, Carolyn C, Goto, Atsushi, Gouda, Hebe N, Guerrant, Richard L, Gugnani, Harish C, Guillemin, Francis, Gunnell, David, Gupta, Rahul, Gupta, Rajeev, Gutiérrez, Reyna A, Hafezi-Nejad, Nima, Hagan, Holly, Hagstromer, Maria, Halasa, Yara A, Hamadeh, Randah R, Hammami, Mouhanad, Hankey, Graeme J, Hao, Yuantao, Harb, Hilda L, Haregu, Tilahun Nigatu, Haro, Josep Maria, Havmoeller, Rasmus, Hay, Simon I, Hedayati, Mohammad T, Heredia-Pi, Ileana B, Hernandez, Lucia, Heuton, Kyle R, Heydarpour, Pouria, Hijar, Martha, Hoek, Hans W, Hoffman, Howard J, Hornberger, John C, Hosgood, H Dean, Hoy, Damian G, Hsairi, Mohamed, Hu, Guoqing, Hu, Howard, Huang, Cheng, Huang, John J, Hubbell, Bryan J, Huiart, Laetitia, Husseini, Abdullatif, Iannarone, Marissa L, Iburg, Kim M, Idrisov, Bulat T, Ikeda, Nayu, Innos, Kaire, Inoue, Manami, Islami, Farhad, Ismayilova, Samaya, Jacobsen, Kathryn H, Jansen, Henrica A, Jarvis, Deborah L, Jassal, Simerjot K, Jauregui, Alejandra, Jayaraman, Sudha, Jeemon, Panniyammakal, Jensen, Paul N, Jha, Vivekanand, Jiang, Fan, Jiang, Guohong, Jiang, Ying, Jonas, Jost B, Juel, Knud, Kan, Haidong, Roseline, Sidibe S Kany, Karam, Nadim E, Karch, André, Karema, Corine K, Karthikeyan, Ganesan, Kaul, Anil, Kawakami, Norito, Kazi, Dhruv S, Kemp, Andrew H, Kengne, Andre P, Keren, Andre, Khader, Yousef S, Khalifa, Shams Eldin Ali Hassan, Khan, Ejaz A, Khang, Young-Ho, Khatibzadeh, Shahab, Khonelidze, Irma, Kieling, Christian, Kim, Daniel, Kim, Sungroul, Kim, Yunjin, Kimokoti, Ruth W, Kinfu, Yohannes, Kinge, Jonas M, Kissela, Brett M, Kivipelto, Miia, Knibbs, Luke D, Knudsen, Ann Kristin, Kokubo, Yoshihiro, Kose, M Rifat, Kosen, Soewarta, Kraemer, Alexander, Kravchenko, Michael, Krishnaswami, Sanjay, Kromhout, Hans, Ku, Tiffany, Defo, Barthelemy Kuate, Bicer, Burcu Kucuk, Kuipers, Ernst J, Kulkarni, Chanda, Kulkarni, Veena S, Kumar, G Anil, Kwan, Gene F, Lai, Taavi, Balaji, Arjun Lakshmana, Lalloo, Ratilal, Lallukka, Tea, Lam, Hilton, Lan, Qing, Lansingh, Van C, Larson, Heidi J, Larsson, Anders, Laryea, Dennis O, Lavados, Pablo M, Lawrynowicz, Alicia E, Leasher, Janet L, Lee, Jong-Tae, Leigh, James, Leung, Ricky, Levi, Miriam, Li, Yichong, Li, Yongmei, Liang, Juan, Liang, Xiaofeng, Lim, Stephen S, Lindsay, M Patrice, Lipshultz, Steven E, Liu, Shiwei, Liu, Yang, Lloyd, Belinda K, Logroscino, Giancarlo, London, Stephanie J, Lopez, Nancy, Lortet-Tieulent, Joannie, Lotufo, Paulo A, Lozano, Rafael, Lunevicius, Raimundas, Ma, Jixiang, Ma, Stefan, Machado, Vasco M P, MacIntyre, Michael F, Magis-Rodriguez, Carlos, Mahdi, Abbas A, Majdan, Marek, Malekzadeh, Reza, Mangalam, Srikanth, Mapoma, Christopher C, Marape, Marape, Marcenes, Wagner, Margolis, David J, Margono, Christopher, Marks, Guy B, Martin, Randall V, Marzan, Melvin B, Mashal, Mohammad T, Masiye, Felix, Mason-Jones, Amanda J, Matsushita, Kunihiro, Matzopoulos, Richard, Mayosi, Bongani M, Mazorodze, Tasara T, McKay, Abigail C, McKee, Martin, McLain, Abigail, Meaney, Peter A, Medina, Catalina, Mehndiratta, Man Mohan, Mejia-Rodriguez, Fabiola, Mekonnen, Wubegzier, Melaku, Yohannes A, Meltzer, Michele, Memish, Ziad A, Mendoza, Walter, Mensah, George A, Meretoja, Atte, Mhimbira, Francis Apolinary, Micha, Renata, Miller, Ted R, Mills, Edward J, Misganaw, Awoke, Mishra, Santosh, Ibrahim, Norlinah Mohamed, Mohammad, Karzan A, Mokdad, Ali H, Mola, Glen L, Monasta, Lorenzo, Hernandez, Julio C Montañez, Montico, Marcella, Moore, Ami R, Morawska, Lidia, Mori, Rintaro, Moschandreas, Joanna, Moturi, Wilkister N, Mozaffarian, Dariush, Mueller, Ulrich O, Mukaigawara, Mitsuru, Mullany, Erin C, Murthy, Kinnari S, Naghavi, Mohsen, Nahas, Ziad, Naheed, Aliya, Naidoo, Kovin S, Naldi, Luigi, Nand, Devina, Nangia, Vinay, Narayan, KM Venkat, Nash, Denis, Neal, Bruce, Nejjari, Chakib, Neupane, Sudan P, Newton, Charles R, Ngalesoni, Frida N, de Dieu Ngirabega, Jean, Nguyen, Grant, Nguyen, Nhung T, Nieuwenhuijsen, Mark J, Nisar, Muhammad I, Nogueira, José R, Nolla, Joan M, Nolte, Sandra, Norheim, Ole F, Norman, Rosana E, Norrving, Bo, Nyakarahuka, Luke, Oh, In-Hwan, Ohkubo, Takayoshi, Olusanya, Bolajoko O, Omer, Saad B, Opio, John Nelson, Orozco, Ricardo, Pagcatipunan, Rodolfo S, Jr., Pain, Amanda W, Pandian, Jeyaraj D, Panelo, Carlo Irwin A, Papachristou, Christina, Park, Eun-Kee, Parry, Charles D, Caicedo, Angel J Paternina, Patten, Scott B, Paul, Vinod K, Pavlin, Boris I, Pearce, Neil, Pedraza, Lilia S, Pedroza, Andrea, Stokic, Ljiljana Pejin, Pekericli, Ayfer, Pereira, David M, Perez-Padilla, Rogelio, Perez-Ruiz, Fernando, Perico, Norberto, Perry, Samuel A L, Pervaiz, Aslam, Pesudovs, Konrad, Peterson, Carrie B, Petzold, Max, Phillips, Michael R, Phua, Hwee Pin, Plass, Dietrich, Poenaru, Dan, Polanczyk, Guilherme V, Polinder, Suzanne, Pond, Constance D, Pope, C Arden, Pope, Daniel, Popova, Svetlana, Pourmalek, Farshad, Powles, John, Prabhakaran, Dorairaj, Prasad, Noela M, Qato, Dima M, Quezada, Amado D, Quistberg, D Alex A, Racapé, Lionel, Rafay, Anwar, Rahimi, Kazem, Rahimi-Movaghar, Vafa, Rahman, Sajjad Ur, Raju, Murugesan, Rakovac, Ivo, Rana, Saleem M, Rao, Mayuree, Razavi, Homie, Reddy, K Srinath, Refaat, Amany H, Rehm, Jürgen, Remuzzi, Giuseppe, Ribeiro, Antonio L, Riccio, Patricia M, Richardson, Lee, Riederer, Anne, Robinson, Margaret, Roca, Anna, Rodriguez, Alina, Rojas-Rueda, David, Romieu, Isabelle, Ronfani, Luca, Room, Robin, Roy, Nobhojit, Ruhago, George M, Rushton, Lesley, Sabin, Nsanzimana, Sacco, Ralph L, Saha, Sukanta, Sahathevan, Ramesh, Sahraian, Mohammad Ali, Salomon, Joshua A, Salvo, Deborah, Sampson, Uchechukwu K, Sanabria, Juan R, Sanchez, Luz Maria, Sánchez-Pimienta, Tania G, Sanchez-Riera, Lidia, Sandar, Logan, Santos, Itamar S, Sapkota, Amir, Satpathy, Maheswar, Saunders, James E, Sawhney, Monika, Saylan, Mete I, Scarborough, Peter, Schmidt, Jürgen C, Schneider, Ione J C, Schöttker, Ben, Schwebel, David C, Scott, James G, Seedat, Soraya, Sepanlou, Sadaf G, Serdar, Berrin, Servan-Mori, Edson E, Shaddick, Gavin, Shahraz, Saeid, Levy, Teresa Shamah, Shangguan, Siyi, She, Jun, Sheikhbahaei, Sara, Shibuya, Kenji, Shin, Hwashin H, Shinohara, Yukito, Shiri, Rahman, Shishani, Kawkab, Shiue, Ivy, Sigfusdottir, Inga D, Silberberg, Donald H, Simard, Edgar P, Sindi, Shireen, Singh, Abhishek, Singh, Gitanjali M, Singh, Jasvinder A, Skirbekk, Vegard, Sliwa, Karen, Soljak, Michael, Soneji, Samir, Søreide, Kjetil, Soshnikov, Sergey, Sposato, Luciano A, Sreeramareddy, Chandrashekhar T, Stapelberg, Nicolas J C, Stathopoulou, Vasiliki, Steckling, Nadine, Stein, Dan J, Stein, Murray B, Stephens, Natalie, Stöckl, Heidi, Straif, Kurt, Stroumpoulis, Konstantinos, Sturua, Lela, Sunguya, Bruno F, Swaminathan, Soumya, Swaroop, Mamta, Sykes, Bryan L, Tabb, Karen M, Takahashi, Ken, Talongwa, Roberto T, Tandon, Nikhil, Tanne, David, Tanner, Marcel, Tavakkoli, Mohammad, Te Ao, Braden J, Teixeira, Carolina M, Téllez Rojo, Martha M, Terkawi, Abdullah S, Texcalac-Sangrador, José Luis, Thackway, Sarah V, Thomson, Blake, Thorne-Lyman, Andrew L, Thrift, Amanda G, Thurston, George D, Tillmann, Taavi, Tobollik, Myriam, Tonelli, Marcello, Topouzis, Fotis, Towbin, Jeffrey A, Toyoshima, Hideaki, Traebert, Jefferson, Tran, Bach X, Trasande, Leonardo, Trillini, Matias, Trujillo, Ulises, Dimbuene, Zacharie Tsala, Tsilimbaris, Miltiadis, Tuzcu, Emin Murat, Uchendu, Uche S, Ukwaja, Kingsley N, Uzun, Selen B, van de Vijver, Steven, Van Dingenen, Rita, van Gool, Coen H, van Os, Jim, Varakin, Yuri Y, Vasankari, Tommi J, Vasconcelos, Ana Maria N, Vavilala, Monica S, Veerman, Lennert J, Velasquez-Melendez, Gustavo, Venketasubramanian, N, Vijayakumar, Lakshmi, Villalpando, Salvador, Violante, Francesco S, Vlassov, Vasiliy Victorovich, Vollset, Stein Emil, Wagner, Gregory R, Waller, Stephen G, Wallin, Mitchell T, Wan, Xia, Wang, Haidong, Wang, JianLi, Wang, Linhong, Wang, Wenzhi, Wang, Yanping, Warouw, Tati S, Watts, Charlotte H, Weichenthal, Scott, Weiderpass, Elisabete, Weintraub, Robert G, Werdecker, Andrea, Wessells, K Ryan, Westerman, Ronny, Whiteford, Harvey A, Wilkinson, James D, Williams, Hywel C, Williams, Thomas N, Woldeyohannes, Solomon M, Wolfe, Charles D A, Wong, John Q, Woolf, Anthony D, Wright, Jonathan L, Wurtz, Brittany, Xu, Gelin, Yan, Lijing L, Yang, Gonghuan, Yano, Yuichiro, Ye, Pengpeng, Yenesew, Muluken, Yentür, Gökalp K, Yip, Paul, Yonemoto, Naohiro, Yoon, Seok-Jun, Younis, Mustafa Z, Younoussi, Zourkaleini, Yu, Chuanhua, Zaki, Maysaa E, Zhao, Yong, Zheng, Yingfeng, Zhou, Maigeng, Zhu, Jun, Zhu, Shankuan, Zou, Xiaonong, Zunt, Joseph R, Lopez, Alan D, Vos, Theo, and Murray, Christopher J

Published
2015
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64. Global, regional, and national disability-adjusted life years (DALYs) for 306 diseases and injuries and healthy life expectancy (HALE) for 188 countries, 1990–2013: quantifying the epidemiological transition

Author

Murray, Christopher J L, Barber, Ryan M, Foreman, Kyle J, Ozgoren, Ayse Abbasoglu, Abd-Allah, Foad, Abera, Semaw F, Aboyans, Victor, Abraham, Jerry P, Abubakar, Ibrahim, Abu-Raddad, Laith J, Abu-Rmeileh, Niveen M, Achoki, Tom, Ackerman, Ilana N, Ademi, Zanfina, Adou, Arsène K, Adsuar, José C, Afshin, Ashkan, Agardh, Emilie E, Alam, Sayed Saidul, Alasfoor, Deena, Albittar, Mohammed I, Alegretti, Miguel A, Alemu, Zewdie A, Alfonso-Cristancho, Rafael, Alhabib, Samia, Ali, Raghib, Alla, François, Allebeck, Peter, Almazroa, Mohammad A, Alsharif, Ubai, Alvarez, Elena, Alvis-Guzman, Nelson, Amare, Azmeraw T, Ameh, Emmanuel A, Amini, Heresh, Ammar, Walid, Anderson, H Ross, Anderson, Benjamin O, Antonio, Carl Abelardo T, Anwari, Palwasha, Arnlöv, Johan, Arsenijevic, Valentina S Arsic, Artaman, Al, Asghar, Rana J, Assadi, Reza, Atkins, Lydia S, Avila, Marco A, Awuah, Baffour, Bachman, Victoria F, Badawi, Alaa, Bahit, Maria C, Balakrishnan, Kalpana, Banerjee, Amitava, Barker-Collo, Suzanne L, Barquera, Simon, Barregard, Lars, Barrero, Lope H, Basu, Arindam, Basu, Sanjay, Basulaiman, Mohammed O, Beardsley, Justin, Bedi, Neeraj, Beghi, Ettore, Bekele, Tolesa, Bell, Michelle L, Benjet, Corina, Bennett, Derrick A, Bensenor, Isabela M, Benzian, Habib, Bernabé, Eduardo, Bertozzi-Villa, Amelia, Beyene, Tariku J, Bhala, Neeraj, Bhalla, Ashish, Bhutta, Zulfiqar A, Bienhoff, Kelly, Bikbov, Boris, Biryukov, Stan, Blore, Jed D, Blosser, Christopher D, Blyth, Fiona M, Bohensky, Megan A, Bolliger, Ian W, Başara, Berrak Bora, Bornstein, Natan M, Bose, Dipan, Boufous, Soufiane, Bourne, Rupert R A, Boyers, Lindsay N, Brainin, Michael, Brayne, Carol E, Brazinova, Alexandra, Breitborde, Nicholas J K, Brenner, Hermann, Briggs, Adam D, Brooks, Peter M, Brown, Jonathan C, Brugha, Traolach S, Buchbinder, Rachelle, Buckle, Geoffrey C, Budke, Christine M, Bulchis, Anne, Bulloch, Andrew G, Campos-Nonato, Ismael R, Carabin, Hélène, Carapetis, Jonathan R, Cárdenas, Rosario, Carpenter, David O, Caso, Valeria, Castañeda-Orjuela, Carlos A, Castro, Ruben E, Catalá-López, Ferrán, Cavalleri, Fiorella, Çavlin, Alanur, Chadha, Vineet K, Chang, Jung-Chen, Charlson, Fiona J, Chen, Honglei, Chen, Wanqing, Chiang, Peggy P, Chimed-Ochir, Odgerel, Chowdhury, Rajiv, Christensen, Hanne, Christophi, Costas A, Cirillo, Massimo, Coates, Matthew M, Coffeng, Luc E, Coggeshall, Megan S, Colistro, Valentina, Colquhoun, Samantha M, Cooke, Graham S, Cooper, Cyrus, Cooper, Leslie T, Coppola, Luis M, Cortinovis, Monica, Criqui, Michael H, Crump, John A, Cuevas-Nasu, Lucia, Danawi, Hadi, Dandona, Lalit, Dandona, Rakhi, Dansereau, Emily, Dargan, Paul I, Davey, Gail, Davis, Adrian, Davitoiu, Dragos V, Dayama, Anand, De Leo, Diego, Degenhardt, Louisa, Del Pozo-Cruz, Borja, Dellavalle, Robert P, Deribe, Kebede, Derrett, Sarah, Jarlais, Don C Des, Dessalegn, Muluken, Dharmaratne, Samath D, Dherani, Mukesh K, Diaz-Torné, Cesar, Dicker, Daniel, Ding, Eric L, Dokova, Klara, Dorsey, E Ray, Driscoll, Tim R, Duan, Leilei, Duber, Herbert C, Ebel, Beth E, Edmond, Karen M, Elshrek, Yousef M, Endres, Matthias, Ermakov, Sergey P, Erskine, Holly E, Eshrati, Babak, Esteghamati, Alireza, Estep, Kara, Faraon, Emerito Jose A, Farzadfar, Farshad, Fay, Derek F, Feigin, Valery L, Felson, David T, Fereshtehnejad, Seyed-Mohammad, Fernandes, Jefferson G, Ferrari, Alize J, Fitzmaurice, Christina, Flaxman, Abraham D, Fleming, Thomas D, Foigt, Nataliya, Forouzanfar, Mohammad H, Fowkes, F Gerry R, Paleo, Urbano Fra., Franklin, Richard C, Fürst, Thomas, Gabbe, Belinda, Gaffikin, Lynne, Gankpé, Fortuné G, Geleijnse, Johanna M, Gessner, Bradford D, Gething, Peter, Gibney, Katherine B, Giroud, Maurice, Giussani, Giorgia, Dantes, Hector Gomez, Gona, Philimon, González-Medina, Diego, Gosselin, Richard A, Gotay, Carolyn C, Goto, Atsushi, Gouda, Hebe N, Graetz, Nicholas, Gugnani, Harish C, Gupta, Rahul, Gupta, Rajeev, Gutiérrez, Reyna A, Haagsma, Juanita, Hafezi-Nejad, Nima, Hagan, Holly, Halasa, Yara A, Hamadeh, Randah R, Hamavid, Hannah, Hammami, Mouhanad, Hancock, Jamie, Hankey, Graeme J, Hansen, Gillian M, Hao, Yuantao, Harb, Hilda L, Haro, Josep Maria, Havmoeller, Rasmus, Hay, Simon I, Hay, Roderick J, Heredia-Pi, Ileana B, Heuton, Kyle R, Heydarpour, Pouria, Higashi, Hideki, Hijar, Martha, Hoek, Hans W, Hoffman, Howard J, Hosgood, H Dean, Hossain, Mazeda, Hotez, Peter J, Hoy, Damian G, Hsairi, Mohamed, Hu, Guoqing, Huang, Cheng, Huang, John J, Husseini, Abdullatif, Huynh, Chantal, Iannarone, Marissa L, Iburg, Kim M, Innos, Kaire, Inoue, Manami, Islami, Farhad, Jacobsen, Kathryn H, Jarvis, Deborah L, Jassal, Simerjot K, Jee, Sun Ha, Jeemon, Panniyammakal, Jensen, Paul N, Jha, Vivekanand, Jiang, Guohong, Jiang, Ying, Jonas, Jost B, Juel, Knud, Kan, Haidong, Karch, André, Karema, Corine K, Karimkhani, Chante, Karthikeyan, Ganesan, Kassebaum, Nicholas J, Kaul, Anil, Kawakami, Norito, Kazanjan, Konstantin, Kemp, Andrew H, Kengne, Andre P, Keren, Andre, Khader, Yousef S, Khalifa, Shams Eldin A, Khan, Ejaz A, Khan, Gulfaraz, Khang, Young-Ho, Kieling, Christian, Kim, Daniel, Kim, Sungroul, Kim, Yunjin, Kinfu, Yohannes, Kinge, Jonas M, Kivipelto, Miia, Knibbs, Luke D, Knudsen, Ann Kristin, Kokubo, Yoshihiro, Kosen, Soewarta, Krishnaswami, Sanjay, Defo, Barthelemy Kuate, Bicer, Burcu Kucuk, Kuipers, Ernst J, Kulkarni, Chanda, Kulkarni, Veena S, Kumar, G Anil, Kyu, Hmwe H, Lai, Taavi, Lalloo, Ratilal, Lallukka, Tea, Lam, Hilton, Lan, Qing, Lansingh, Van C, Larsson, Anders, Lawrynowicz, Alicia E B, Leasher, Janet L, Leigh, James, Leung, Ricky, Levitz, Carly E, Li, Bin, Li, Yichong, Li, Yongmei, Lim, Stephen S, Lind, Maggie, Lipshultz, Steven E, Liu, Shiwei, Liu, Yang, Lloyd, Belinda K, Lofgren, Katherine T, Logroscino, Giancarlo, Looker, Katharine J, Lortet-Tieulent, Joannie, Lotufo, Paulo A, Lozano, Rafael, Lucas, Robyn M, Lunevicius, Raimundas, Lyons, Ronan A, Ma, Stefan, Macintyre, Michael F, Mackay, Mark T, Majdan, Marek, Malekzadeh, Reza, Marcenes, Wagner, Margolis, David J, Margono, Christopher, Marzan, Melvin B, Masci, Joseph R, Mashal, Mohammad T, Matzopoulos, Richard, Mayosi, Bongani M, Mazorodze, Tasara T, Mcgill, Neil W, Mcgrath, John J, Mckee, Martin, Mclain, Abigail, Meaney, Peter A, Medina, Catalina, Mehndiratta, Man Mohan, Mekonnen, Wubegzier, Melaku, Yohannes A, Meltzer, Michele, Memish, Ziad A, Mensah, George A, Meretoja, Atte, Mhimbira, Francis A, Micha, Renata, Miller, Ted R, Mills, Edward J, Mitchell, Philip B, Mock, Charles N, Ibrahim, Norlinah Mohamed, Mohammad, Karzan A, Mokdad, Ali H, Mola, Glen L D, Monasta, Lorenzo, Hernandez, Julio C Montañez, Montico, Marcella, Montine, Thomas J, Mooney, Meghan D, Moore, Ami R, Moradi-Lakeh, Maziar, Moran, Andrew E, Mori, Rintaro, Moschandreas, Joanna, Moturi, Wilkister N, Moyer, Madeline L, Mozaffarian, Dariush, Msemburi, William T, Mueller, Ulrich O, Mukaigawara, Mitsuru, Mullany, Erin C, Murdoch, Michele E, Murray, Joseph, Murthy, Kinnari S, Naghavi, Mohsen, Naheed, Aliya, Naidoo, Kovin S, Naldi, Luigi, Nand, Devina, Nangia, Vinay, Narayan, K M Venkat, Nejjari, Chakib, Neupane, Sudan P, Newton, Charles R, Ng, Marie, Ngalesoni, Frida N, Nguyen, Grant, Nisar, Muhammad I, Nolte, Sandra, Norheim, Ole F, Norman, Rosana E, Norrving, Bo, Nyakarahuka, Luke, Oh, In-Hwan, Ohkubo, Takayoshi, Ohno, Summer L, Olusanya, Bolajoko O, Opio, John Nelson, Ortblad, Katrina, Ortiz, Alberto, Pain, Amanda W, Pandian, Jeyaraj D, Panelo, Carlo Irwin A, Papachristou, Christina, Park, Eun-Kee, Park, Jae-Hyun, Patten, Scott B, Patton, George C, Paul, Vinod K, Pavlin, Boris I, Pearce, Neil, Pereira, David M, Perez-Padilla, Rogelio, Perez-Ruiz, Fernando, Perico, Norberto, Pervaiz, Aslam, Pesudovs, Konrad, Peterson, Carrie B, Petzold, Max, Phillips, Michael R, Phillips, Bryan K, Phillips, David E, Piel, Frédéric B, Plass, Dietrich, Poenaru, Dan, Polinder, Suzanne, Pope, Daniel, Popova, Svetlana, Poulton, Richie G, Pourmalek, Farshad, Prabhakaran, Dorairaj, Prasad, Noela M, Pullan, Rachel L, Qato, Dima M, Quistberg, D Alex, Rafay, Anwar, Rahimi, Kazem, Rahman, Sajjad U, Raju, Murugesan, Rana, Saleem M, Razavi, Homie, Reddy, K Srinath, Refaat, Amany, Remuzzi, Giuseppe, Resnikoff, Serge, Ribeiro, Antonio L, Richardson, Lee, Richardus, Jan Hendrik, Roberts, D Allen, Rojas-Rueda, David, Ronfani, Luca, Roth, Gregory A, Rothenbacher, Dietrich, Rothstein, David H, Rowley, Jane T, Roy, Nobhojit, Ruhago, George M, Saeedi, Mohammad Y, Saha, Sukanta, Sahraian, Mohammad Ali, Sampson, Uchechukwu K A, Sanabria, Juan R, Sandar, Logan, Santos, Itamar S, Satpathy, Maheswar, Sawhney, Monika, Scarborough, Peter, Schneider, Ione J, Schöttker, Ben, Schumacher, Austin E, Schwebel, David C, Scott, James G, Seedat, Soraya, Sepanlou, Sadaf G, Serina, Peter T, Servan-Mori, Edson E, Shackelford, Katya A, Shaheen, Amira, Shahraz, Saeid, Levy, Teresa Shamah, Shangguan, Siyi, She, Jun, Sheikhbahaei, Sara, Shi, Peilin, Shibuya, Kenji, Shinohara, Yukito, Shiri, Rahman, Shishani, Kawkab, Shiue, Ivy, Shrime, Mark G, Sigfusdottir, Inga D, Silberberg, Donald H, Simard, Edgar P, Sindi, Shireen, Singh, Abhishek, Singh, Jasvinder A, Singh, Lavanya, Skirbekk, Vegard, Slepak, Erica Leigh, Sliwa, Karen, Soneji, Samir, Søreide, Kjetil, Soshnikov, Sergey, Sposato, Luciano A, Sreeramareddy, Chandrashekhar T, Stanaway, Jeffrey D, Stathopoulou, Vasiliki, Stein, Dan J, Stein, Murray B, Steiner, Caitlyn, Steiner, Timothy J, Stevens, Antony, Stewart, Andrea, Stovner, Lars J, Stroumpoulis, Konstantinos, Sunguya, Bruno F, Swaminathan, Soumya, Swaroop, Mamta, Sykes, Bryan L, Tabb, Karen M, Takahashi, Ken, Tandon, Nikhil, Tanne, David, Tanner, Marcel, Tavakkoli, Mohammad, Taylor, Hugh R, Ao, Braden J Te, Tediosi, Fabrizio, Temesgen, Awoke M, Templin, Tara, Ten Have, Margreet, Tenkorang, Eric Y, Terkawi, Abdullah S, Thomson, Blake, Thorne-Lyman, Andrew L, Thrift, Amanda G, Thurston, George D, Tillmann, Taavi, Tonelli, Marcello, Topouzis, Fotis, Toyoshima, Hideaki, Traebert, Jefferson, Tran, Bach X, Trillini, Matias, Truelsen, Thomas, Tsilimbaris, Miltiadis, Tuzcu, Emin M, Uchendu, Uche S, Ukwaja, Kingsley N, Undurraga, Eduardo A, Uzun, Selen B, Van Brakel, Wim H, Van De Vijver, Steven, van Gool, Coen H, Van Os, Jim, Vasankari, Tommi J, Venketasubramanian, N, Violante, Francesco S, Vlassov, Vasiliy V, Vollset, Stein Emil, Wagner, Gregory R, Wagner, Joseph, Waller, Stephen G, Wan, Xia, Wang, Haidong, Wang, Jianli, Wang, Linhong, Warouw, Tati S, Weichenthal, Scott, Weiderpass, Elisabete, Weintraub, Robert G, Wenzhi, Wang, Werdecker, Andrea, Westerman, Ronny, Whiteford, Harvey A, Wilkinson, James D, Williams, Thomas N, Wolfe, Charles D, Wolock, Timothy M, Woolf, Anthony D, Wulf, Sarah, Wurtz, Brittany, Xu, Gelin, Yan, Lijing L, Yano, Yuichiro, Ye, Pengpeng, Yentür, Gökalp K, Yip, Paul, Yonemoto, Naohiro, Yoon, Seok-Jun, Younis, Mustafa Z, Yu, Chuanhua, Zaki, Maysaa E, Zhao, Yong, Zheng, Yingfeng, Zonies, David, Zou, Xiaonong, Salomon, Joshua A, Lopez, Alan D, and Vos, Theo

Published
2015
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67. What's the low back pain problem represented to be? An analysis of discourse of the Australian policy directives.

Author

Costa, Nathalia, Blyth, Fiona M., Parambath, Sarika, and Huckel Schneider, Carmen

Subjects
*LUMBAR pain, *HEALTH policy, *MEDICINE information services, *SOCIAL determinants of health, *PATIENT decision making, *MEDICAL protocols, *CONCEPTUAL structures, *HEALTH information services, *HEALTH, *INFORMATION resources, *DISCOURSE analysis, *MEDICAL referrals, *RESEARCH funding, *DECISION making in clinical medicine, *DATA analysis software, *CONTENT analysis, *THEMATIC analysis, *PAIN management, *WORLD Wide Web, *COMORBIDITY
Abstract

Low back pain (LBP) directives provide information about how LBP should be managed, communicated and navigated in complex health systems, making them an important form of policy. This study aimed to examine how LBP is problematised (represented) in Australian directives. We employed an analysis of discourse of LBP directives drawing on Bacchi's "What's the problem represented to be?" policy problematisation approach. Our analysis suggests that LBP is problematised as a symptom that tends to improve when individuals take responsibility for themselves, but may require care at times. The way in which LBP is represented in the directives excludes important aspects, such as the uncertainties of scientific knowledge, paradigms other than (post)positivist, multimorbidity, social and structural determinants of health. LBP directives may benefit from problematisations of LBP that consider the ongoing nature of LBP and broader contextual factors that impact on both LBP outcomes and care, beyond individual responsibility. Consideration of a wider range of paradigms and expanded evidence base may also be beneficial, as these are likely to enable individuals, clinicians and the Australian healthcare system to address LBP while dealing with its complexities, enabling real-world changes to lessen the LBP burden. Healthcare professionals who work with people who experience low back pain (LBP) may benefit from critically reflecting about discourses embedded in policy directives. Healthcare professionals may consider engaging in policy changes processes to expand the discourses on which LBP policy directives rely. Healthcare professionals' ability to enact policy recommendations may be enhanced by consideration of the fluctuating nature of LBP, uncertainties, multimorbidity and determinants of health. [ABSTRACT FROM AUTHOR]

Published
2023
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68. Oral health‐related quality of life of older Australian men.

Author

Wright, Fredrick Alan Clive, Shu, Ellie C.‐C., Cumming, Robert G., Naganathan, Vasi, Blyth, Fiona M., Hirani, Vasant, Le Couteur, David G., Handelsman, David J., Seibel, Markus J., Waite, Louise M., and Stanaway, Fiona F.

Subjects
CONFIDENCE intervals, ORAL health, MULTIVARIATE analysis, MEN, HEALTH status indicators, REGRESSION analysis, QUALITY of life, QUESTIONNAIRES, DISEASE prevalence, RESEARCH funding, SOCIODEMOGRAPHIC factors, SMOKING, LONGITUDINAL method, OLD age
Abstract

Objectives: The aims of this study were to assess oral health‐related quality of life (OHRQoL) in a cohort of older Australian men and explore the association between their general health conditions, socio‐demographic factors and OHRQoL. Methods: The Concord Health and Ageing in Men Project (CHAMP) is a cohort study of the health of a representative sample of Australian men, initiated in 2005–2006 with an initial sample of 1705 men 70 years or over. Participants completed a self‐administered health and socio‐demographic questionnaire and attended an interview and clinical assessment at baseline and each of three follow‐up assessments. Information on oral health and responses to the Oral Health Impact Profile (OHIP‐14) were collected in the 4th follow‐up in which 778 men completed the OHIP‐14 questionnaire and 614 men had a dental assessment. The prevalence of oral health impact was defined as a response of fairly often or very often to one or more of the OHIP‐14 questions. Mean OHIP‐14 scores were calculated for the 14 questions and used as the dependent variable in the regression analyses. Zero‐inflated Poisson regression was used to estimate prevalence rate ratios (PRR). Results: Only 10% of men presented oral health impacts. In multivariate regression modelling, being born in Italy/Greece (PRR: 2.16, 95% CI: 1.93–2.42) or in other countries (PRR: 2.12, 95% CI: 1.89–2.38), having poor self‐rated general health (PRR: 1.38, 95% CI: 1.24–1.53), having poor mental wellbeing (PRR: 1.14, 95% CI: 1.04–1.24), having ≥6 depressive symptoms (PRR: 1.18, 95% CI: 1.05–1.32), being a current smoker (PRR: 1.34, 95% CI: 1.06–1.70) and having more decayed tooth surfaces (PRR:1.01, 95% CI: 1.00–1.02) were associated with higher impact scores. Conclusions: Overall, older Australian men exhibit good oral health‐related quality of life. The inter‐relationship between perceptions of general health and well‐being, health and oral health variables and social background supports policy objectives of closer integration of general health and oral health services for older Australian men. [ABSTRACT FROM AUTHOR]

Published
2023
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69. DCMEX coordinated aircraft and ground observations: Microphysics, aerosol and dynamics during cumulonimbus development.

Author

Finney, Declan L., Blyth, Alan M., Gallagher, Martin, Huihui Wu, Nott, Graeme, Biggerstaff, Mike, Sonnenfeld, Richard G., Daily, Martin, Walker, Dan, Dufton, David, Bower, Keith, Böing, Steven, Choularton, Thomas, Crosier, Jonathan, Groves, James, Field, Paul R., Coe, Hugh, Murray, Benjamin J., Lloyd, Gary, and Marsden, Nicholas A.

Subjects
*CLIMATE change models, *MICROPHYSICS, *CLIMATE sensitivity, *AEROSOLS, *CLOUD physics, *CUMULONIMBUS
Abstract

Sensitivity of global temperature to rising CO2 remains highly uncertain. One of the greatest sources of uncertainty arises from cloud feedbacks associated with deep convective anvils. For deep convective clouds, their growth and characteristics are substantially controlled by mixed-phase microphysical processes. However, there remain several questions about cloud microphysical processes, especially in deep, mixed-phase clouds. Meanwhile, the representation of these processes in global climate models is limited. As such, the Deep ConvectiveMicrophysics Experiment (DCMEX) has undertaken an in-situ aircraft and ground-based measurement campaign. The data, combined with operational satellite observations and modelling, will help establish new understanding from the smallest, cloud and aerosol particle scales through to the largest, cloud-system and climate scales. DCMEX is one of four projects in the UK Natural Environment Research Council, Uncertainty in climate sensitivity due to clouds, CloudSense programme. Along with other CloudSense projects, DCMEX will support progress in reducing the uncertainty in cloud feedbacks and equilibrium climate sensitivity. This paper lays out the underpinning dataset from the DCMEX summer 2022 field campaign. Its content describes the coordinated operation and technical details of the broad range of aerosol, cloud physics, radar, thermodynamics, dynamics, electric field and weather instruments deployed. In addition, an overview of the characteristics of campaign cases illustrates the complementary operational observations available, as well as demonstrating the breadth of the campaign cases observed. [ABSTRACT FROM AUTHOR]

Published
2023
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70. Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013

Author

Vos, Theo, Barber, Ryan M, Bell, Brad, Bertozzi-Villa, Amelia, Biryukov, Stan, Bolliger, Ian, Charlson, Fiona, Davis, Adrian, Degenhardt, Louisa, Dicker, Daniel, Duan, Leilei, Erskine, Holly, Feigin, Valery L, Ferrari, Alize J, Fitzmaurice, Christina, Fleming, Thomas, Graetz, Nicholas, Guinovart, Caterina, Haagsma, Juanita, Hansen, Gillian M, Hanson, Sarah Wulf, Heuton, Kyle R, Higashi, Hideki, Kassebaum, Nicholas, Kyu, Hmwe, Laurie, Evan, Liang, Xiofeng, Lofgren, Katherine, Lozano, Rafael, MacIntyre, Michael F, Moradi-Lakeh, Maziar, Naghavi, Mohsen, Nguyen, Grant, Odell, Shaun, Ortblad, Katrina, Roberts, David Allen, Roth, Gregory A, Sandar, Logan, Serina, Peter T, Stanaway, Jeffrey D, Steiner, Caitlyn, Thomas, Bernadette, Vollset, Stein Emil, Whiteford, Harvey, Wolock, Timothy M, Ye, Pengpeng, Zhou, Maigeng, Ãvila, Marco A, Aasvang, Gunn Marit, Abbafati, Cristiana, Ozgoren, Ayse Abbasoglu, Abd-Allah, Foad, Aziz, Muna I Abdel, Abera, Semaw F, Aboyans, Victor, Abraham, Jerry P, Abraham, Biju, Abubakar, Ibrahim, Abu-Raddad, Laith J, Abu-Rmeileh, Niveen ME, Aburto, Tania C, Achoki, Tom, Ackerman, Ilana N, Adelekan, Ademola, Ademi, Zanfina, Adou, Arsène K, Adsuar, Josef C, Arnlov, Johan, Agardh, Emilie E, Al Khabouri, Mazin J, Alam, Sayed Saidul, Alasfoor, Deena, Albittar, Mohammed I, Alegretti, Miguel A, Aleman, Alicia V, Alemu, Zewdie A, Alfonso-Cristancho, Rafael, Alhabib, Samia, Ali, Raghib, Alla, Francois, Allebeck, Peter, Allen, Peter J, AlMazroa, Mohammad AbdulAziz, Alsharif, Ubai, Alvarez, Elena, Alvis-Guzman, Nelson, Ameli, Omid, Amini, Heresh, Ammar, Walid, Anderson, Benjamin O, Anderson, H. Ross, Antonio, Carl Abelardo T, Anwari, Palwasha, Apfel, Henry, Arsenijevic, Valentain S Arsic, Artaman, Al, Asghar, Rana J, Assadi, Reza, Atkins, Lydia S, Atkinson, Charles, Badawi, Alaa, Bahit, Maria C, Bakfalouni, Talal, Balakrishnan, Kalpana, Balalla, Shivanthi, Banerjee, Amitava, Barker-Collo, Suzanne L, Barquera, Simon, Barregard, Lars, Barrero, Lope H, Basu, Sanjay, Basu, Arindam, Baxter, Amanda, Beardsley, Justin, Bedi, Neeraj, Beghi, Ettore, Bekele, Tolesa, Bell, Michelle L, Benjet, Corina, Bennett, Derrick A, Bensenor, Isabela M, Benzian, Habib, Bernabe, Eduardo, Beyene, Tariku J, Bhala, Neeraj, Bhalla, Ashish, Bhutta, Zulfiqar, Bienhoff, Kelly, Bikbov, Boris, Abdulhak, Aref Bin, Blore, Jed D, Blyth, Fiona M, Bohensky, Megan A, Basara, Berrak Bora, Borges, Guilherme, Bornstein, Natan M, Bose, Dipan, Boufous, Soufiane, Bourne, Rupert R, Boyers, Lindsay N, Brainin, Michael, Brauer, Michael, Brayne, Carol EG, Brazinova, Alexandra, Breitborde, Nicholas JK, Brenner, Hermann, Briggs, Adam DM, Brooks, Peter M, Brown, Jonathan, Brugha, Traolach S, Buchbinder, Rachelle, Buckle, Geoffrey C, Bukhman, Gene, Bulloch, Andrew G, Burch, Michael, Burnett, Richard, Cardenas, Rosario, Cabral, Norberto L, Nonato, Ismael R Campos, Campuzano, Julio C, Carapetis, Jonathan R, Carpenter, David O, Caso, Valeria, Castaneda-Orjuela, Carlos A, Catala-Lopez, Ferran, Chadha, Vineet K, Chang, Jung-Chen, Chen, Honglei, Chen, Wanqing, Chiang, Peggy P, Chimed-Ochir, Odgerel, Chowdhury, Rajiv, Christensen, Hanne, Christophi, Costas A, Chugh, Sumeet S, Cirillo, Massimo, Coggeshall, Megan, Cohen, Aaron, Colistro, Valentina, Colquhoun, Samantha M, Contreras, Alejandra G, Cooper, Leslie T, Cooper, Cyrus, Cooperrider, Kimberly, Coresh, Josef, Cortinovis, Monica, Criqui, Michael H, Crump, John A, Cuevas-Nasu, Lucia, Dandona, Rakhi, Dandona, Lalit, Dansereau, Emily, Dantes, Hector G, Dargan, Paul I, Davey, Gail, Davitoiu, Dragos V, Dayama, Anand, De la Cruz-Gongora, Vanessa, de la Vega, Shelley F, De Leo, Diego, del Pozo-Cruz, Borja, Dellavalle, Robert P, Deribe, Kebede, Derrett, Sarah, Des Jarlais, Don C, Dessalegn, Muluken, deVeber, Gabrielle A, Dharmaratne, Samath D, Diaz-Torne, Cesar, Ding, Eric L, Dokova, Klara, Dorsey, E R, Driscoll, Tim R, Duber, Herbert, Durrani, Adnan M, Edmond, Karen M, Ellenbogen, Richard G, Endres, Matthias, Ermakov, Sergey P, Eshrati, Babak, Esteghamati, Alireza, Estep, Kara, Fahimi, Saman, Farzadfar, Farshad, Fay, Derek FJ, Felson, David T, Fereshtehnejad, Seyed-Mohammad, Fernandes, Jefferson G, Ferri, Cluesa P, Flaxman, Abraham, Foigt, Nataliya, Foreman, Kyle J, Fowkes, F Gerry R, Franklin, Richard C, Furst, Thomas, Futran, Neal D, Gabbe, Belinda J, Gankpe, Fortune G, Garcia-Guerra, Francisco A, Geleijnse, Johanna M, Gessner, Bradford D, Gibney, Katherine B, Gillum, Richard F, Ginawi, Ibrahim A, Giroud, Maurice, Giussani, Giorgia, Goenka, Shifalika, Goginashvili, Ketevan, Gona, Philimon, de Cosio, Teresita Gonzalez, Gosselin, Richard A, Gotay, Carolyn C, Goto, Atsushi, Gouda, Hebe N, Guerrant, Richard l, Gugnani, Harish C, Gunnell, David, Gupta, Rajeev, Gupta, Rahul, Gutierrez, Reyna A, Hafezi-Nejad, Nima, Hagan, Holly, Halasa, Yara, Hamadeh, Randah R, Hamavid, Hannah, Hammami, Mouhanad, Hankey, Graeme J, Hao, Yuantao, Harb, Hilda L, Haro, Josep Maria, Havmoeller, Rasmus, Hay, Roderick J, Hay, Simon, Hedayati, Mohammad T, Pi, Ileana B Heredia, Heydarpour, Pouria, Hijar, Martha, Hoek, Hans W, Hoffman, Howard J, Hornberger, John C, Hosgood, H. Dean, Hossain, Mazeda, Hotez, Peter J, Hoy, Damian G, Hsairi, Mohamed, Hu, Howard, Hu, Guoqing, Huang, John J, Huang, Cheng, Huiart, Laetitia, Husseini, Abdullatif, Iannarone, Marissa, Iburg, Kim M, Innos, Kaire, Inoue, Manami, Jacobsen, Kathryn H, Jassal, Simerjot K, Jeemon, Panniyammakal, Jensen, Paul N, Jha, Vivekanand, Jiang, Guohong, Jiang, Ying, Jonas, Jost B, Joseph, Jonathan, Juel, Knud, Kan, Haidong, Karch, Andre, Karimkhani, Chante, Karthikeyan, Ganesan, Katz, Ronit, Kaul, Anil, Kawakami, Norito, Kazi, Dhruv S, Kemp, Andrew H, Kengne, Andre P, Khader, Yousef S, Khalifa, Shams Eldin AH, Khan, Ejaz A, Khan, Gulfaraz, Khang, Young-Ho, Khonelidze, Irma, Kieling, Christian, Kim, Daniel, Kim, Sungroul, Kimokoti, Ruth W, Kinfu, Yohannes, Kinge, Jonas M, Kissela, Brett M, Kivipelto, Miia, Knibbs, Luke, Knudsen, Ann Kristin, Kokubo, Yoshihiro, Kosen, Soewarta, Kramer, Alexander, Kravchenko, Michael, Krishnamurthi, Rita V, Krishnaswami, Sanjay, Defo, Barthelemy Kuate, Bicer, Burcu Kucuk, Kuipers, Ernst J, Kulkarni, Veena S, Kumar, Kaushalendra, Kumar, G Anil, Kwan, Gene F, Lai, Taavi, Lalloo, Ratilal, Lam, Hilton, Lan, Qing, Lansingh, Van C, Larson, Heidi, Larsson, Anders, Lawrynowicz, Alicia EB, Leasher, Janet L, Lee, Jong-Tae, Leigh, James, Leung, Ricky, Levi, Miriam, Li, Bin, Li, Yichong, Li, Yongmei, liang, Juan, Lim, Stephen, Lin, Hsien-Ho, Lind, Margaret, Lindsay, M Patrice, Lipshultz, Steven E, Liu, Shiwei, Lloyd, Belinda K, Ohno, Summer Lockett, Logroscino, Giancarlo, Looker, Katharine J, Lopez, Alan D, Lopez-Olmedo, Nancy, Lortet-Tieulent, Joannie, Lotufo, Paulo A, Low, Nicola, Lucas, Robyn M, Lunevicius, Raimundas, Lyons, Ronan A, Ma, Jixiang, Ma, Stefan, Mackay, Mark T, Majdan, Marek, Malekzadeh, Reza, Mapoma, Christopher C, Marcenes, Wagner, March, Lyn M, Margono, Chris, Marks, Guy B, Marzan, Melvin B, Masci, Joseph R, Mason-Jones, Amanda J, Matzopoulos, Richard G, Mayosi, Bongani M, Mazorodze, Tasara T, McGill, Neil W, McGrath, John J, McKee, Martin, McLain, Abby, McMahon, Brian J, Meaney, Peter A, Mehndiratta, Man Mohan, Mejia-Rodriguez, Fabiola, Mekonnen, Wubegzier, Melaku, Yohannes A, Meltzer, Michele, Memish, Ziad A, Mensah, George, Meretoja, Atte, Mhimbira, Francis A, Micha, Renata, Miller, Ted R, Mills, Edward J, Mitchell, Philip B, Mock, Charles N, Moffitt, Terrie E, Ibrahim, Norlinah Mohamed, Mohammad, Karzan A, Mokdad, Ali H, Mola, Glen L, Monasta, Lorenzo, Montico, Marcella, Montine, Thomas J, Moore, Ami R, Moran, Andrew E, Morawska, Lidia, Mori, Rintaro, Moschandreas, Joanna, Moturi, Wilkister N, Moyer, Madeline, Mozaffarian, Dariush, Mueller, Ulrich O, Mukaigawara, Mitsuru, Murdoch, Michele E, Murray, Joseph, Murthy, Kinnari S, Naghavi, Paria, Nahas, Ziad, Naheed, Aliya, Naidoo, Kovin S, Naldi, Luigi, Nand, Devina, Nangia, Vinay, Narayan, K.M. Venkat, Nash, Denis, Nejjari, Chakib, Neupane, Sudan P, Newman, Lori M, Newton, Charles R, Ng, Marie, Ngalesoni, Frida N, Nhung, Nguyen T, Nisar, Muhammad I, Nolte, Sandra, Norheim, Ole F, Norman, Rosana E, Norrving, Bo, Nyakarahuka, Luke, Oh, In Hwan, Ohkubo, Takayoshi, Omer, Saad B, Opio, John Nelson, Ortiz, Alberto, Pandian, Jeyaraj D, Panelo, Carlo Irwin A, Papachristou, Christina, Park, Eun-Kee, Parry, Charles D, Caicedo, Angel J Paternina, Patten, Scott B, Paul, Vinod K, Pavlin, Boris I, Pearce, Neil, Pedraza, Lilia S, Pellegrini, Carlos A, Pereira, David M, Perez-Ruiz, Fernando P, Perico, Norberto, Pervaiz, Aslam, Pesudovs, Konrad, Peterson, Carrie B, Petzold, Max, Phillips, Michael R, Phillips, David, Phillips, Bryan, Piel, Frederic B, Plass, Dietrich, Poenaru, Dan, Polanczyk, Guilherme V, Polinder, Suzanne, Pope, C A, Popova, Svetlana, Poulton, Richie G, Pourmalek, Farshad, Prabhakaran, Dorairaj, Prasad, Noela M, Qato, Dima, Quistberg, D A, Rafay, Anwar, Rahimi, Kazem, Rahimi-Movaghar, Vafa, Rahman, Sajjad ur, Raju, Murugesan, Rakovac, Ivo, Rana, Saleem M, Razavi, Homie, Refaat, Amany, Rehm, Jurgen, Remuzzi, Giuseppe, Resnikoff, Serge, Ribeiro, Antonio L, Riccio, Patricia M, Richardson, Lee, Richardus, Jan Hendrik, Riederer, Anne M, Robinson, Margot, Roca, Anna, Rodriguez, Alina, Rojas-Rueda, David, Ronfani, Luca, Rothenbacher, Dietrich, Roy, Nobhojit, Ruhago, George M, Sabin, Nsanzimana, Sacco, Ralph L, Ksoreide, Kjetil, Saha, Sukanta, Sahathevan, Ramesh, Sahraian, Mohammad Ali, Sampson, Uchechukwu, Sanabria, Juan R, Sanchez-Riera, Lidia, Santos, Itamar S, Satpathy, Maheswar, Saunders, James E, Sawhney, Monika, Saylan, Mete I, Scarborough, Peter, Schoettker, Ben, Schneider, Ione JC, Schwebel, David C, Scott, James G, Seedat, Soraya, Sepanlou, Sadaf G, Serdar, Berrin, Servan-Mori, Edson E, Shackelford, Katya, Shaheen, Amira, Shahraz, Saeid, Levy, Teresa Shamah, Shangguan, Siyi, She, Jun, Sheikhbahaei, Sara, Shepard, Donald S, Shi, Peilin, Shibuya, Kenji, Shinohara, Yukito, Shiri, Rahman, Shishani, Kawkab, Shiue, Ivy, Shrime, Mark G, Sigfusdottir, Inga D, Silberberg, Donald H, Simard, Edgar P, Sindi, Shireen, Singh, Jasvinder A, Singh, Lavanya, Skirbekk, Vegard, Sliwa, Karen, Soljak, Michael, Soneji, Samir, Soshnikov, Sergey S, Speyer, Peter, Sposato, Luciano A, Sreeramareddy, Chandrashekhar T, Stoeckl, Heidi, Stathopoulou, Vasiliki Kalliopi, Steckling, Nadine, Stein, Murray B, Stein, Dan J, Steiner, Timothy J, Stewart, Andrea, Stork, Eden, Stovner, Lars J, Stroumpoulis, Konstantinos, Sturua, Lela, Sunguya, Bruno F, Swaroop, Mamta, Sykes, Bryan L, Tabb, Karen M, Takahashi, Ken, Tan, Feng, Tandon, Nikhil, Tanne, David, Tanner, Marcel, Tavakkoli, Mohammad, Taylor, Hugh R, Te Ao, Braden J, Temesgen, Awoke Misganaw, Have, Margreet Ten, Tenkorang, Eric Yeboah, Terkawi, Abdullah Sulieman, Theadom, Alice M, Thomas, Elissa, Thorne-Lyman, Andrew L, Thrift, Amanda G, Tleyjeh, Imad M, Tonelli, Marcello, Topouzis, Fotis, Towbin, Jeffrey A, Toyoshima, Hideaki, Traebert, Jefferson, Tran, Bach X, Trasande, Leonardo, Trillini, Matias, Truelsen, Thomas, Trujillo, Ulises, Tsilimbaris, Miltiadis, Tuzcu, Emin M, Ukwaja, Kingsley N, Undurraga, Eduardo A, Uzun, Selen B, van Brakel, Wim H, van de Vijver, Steven, Dingenen, Rita Van, van Gool, Coen H, Varakin, Yuri Y, Vasankari, Tommi J, Vavilala, Monica S, Veerman, Lennert J, Velasquez-Melendez, Gustavo, Venketasubramanian, Narayanaswamy, Vijayakumar, Lakshmi, Villalpando, Salvador, Violante, Francesco S, Vlassov, Vasiliy V, Waller, Stephen, Wallin, Mitchell T, Wan, Xia, Wang, Linhong, Wang, JianLi, Wang, Yanping, Warouw, Tati S, Weichenthal, Scott, Weiderpass, Elisabete, Weintraub, Robert G, Werdecker, Andrea, Wessells, K. Ryan R, Westerman, Ronny, Wilkinson, James D, Williams, Hywel C, Williams, Thomas N, Woldeyohannes, Solomon M, Wolfe, Charles DA, Wong, John Q, Wong, Haidong, Woolf, Anthony D, Wright, Jonathan L, Wurtz, Brittany, Xu, Gelin, Yang, Gonghuan, Yano, Yuichiro, Yenesew, Muluken A, Yentur, Gokalp K, Yip, Paul, Yonemoto, Naohiro, Yoon, Seok-Jun, Younis, Mustafa, Yu, Chuanhua, Kim, Kim Yun, Zaki, Maysaa El Sayed, Zhang, Yong, Zhao, Zheng, Zhao, Yong, Zhu, Jun, Zonies, David, Zunt, Joseph R, Salomon, Joshua A, and Murray, Christopher JL

Published
2015
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86. Clinical practice guideline for deprescribing opioid analgesics: summary of recommendations.

Author

Langford, Aili V, Lin, Christine CW, Bero, Lisa, Blyth, Fiona M, Doctor, Jason, Holliday, Simon, Jeon, Yun‐Hee, Moullin, Joanna, Murnion, Bridin, Nielsen, Suzanne, Osman, Rawa, Penm, Jonathan, Reeve, Emily, Reid, Sharon, Wale, Janet, Schneider, Carl R, and Gnjidic, Danijela

Abstract

Introduction: Long term opioids are commonly prescribed to manage pain. Dose reduction or discontinuation (deprescribing) can be challenging, even when the potential harms of continuation outweigh the perceived benefits. The Evidence‐based clinical practice guideline for deprescribing opioid analgesics was developed using robust guideline development processes and Grading of Recommendations, Assessment, Development and Evaluation (GRADE) methodology, and contains deprescribing recommendations for adults prescribed opioids for pain. Main recommendations: Eleven recommendations provide advice about when, how and for whom opioid deprescribing should be considered, while noting the need to consider each person's goals, values and preferences. The recommendations aim to achieve: implementation of a deprescribing plan at the point of opioid initiation;initiation of opioid deprescribing for persons with chronic non‐cancer or chronic cancer‐survivor pain if there is a lack of overall and clinically meaningful improvement in function, quality of life or pain, a lack of progress towards meeting agreed therapeutic goals, or the person is experiencing serious or intolerable opioid‐related adverse effects;gradual and individualised deprescribing, with regular monitoring and review;consideration of opioid deprescribing for individuals at high risk of opioid‐related harms;avoidance of opioid deprescribing for persons nearing the end of life unless clinically indicated;avoidance of opioid deprescribing for persons with a severe opioid use disorder, with the initiation of evidence‐based care, such as medication‐assisted treatment of opioid use disorder; anduse of evidence‐based co‐interventions to facilitate deprescribing, including interdisciplinary, multidisciplinary or multimodal care. Changes in management as a result of these guidelines: To our knowledge, these are the first evidence‐based guidelines for opioid deprescribing. The recommendations intend to facilitate safe and effective deprescribing to improve the quality of care for persons taking opioids for pain. [ABSTRACT FROM AUTHOR]

Published
2023
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92. Mixed Evidence of an Association between Self-Rated Hearing Difficulties and Falls: Prospective Analysis of Two Longitudinal Studies

Author

Kiely, Kim M., primary, Khalatbari-Soltani, Saman, additional, Blyth, Fiona M., additional, Naganathan, Vasikaran, additional, Handelsman, David J., additional, Waite, Louise M., additional, Le Couteur, David G., additional, Mortby, Moyra E., additional, Cumming, Robert G., additional, and Anstey, Kaarin J., additional

Published
2022
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93. Oral health‐related quality of life of older Australian men

Author

Wright, Fredrick Alan Clive, primary, Shu, Ellie C.‐C., additional, Cumming, Robert G., additional, Naganathan, Vasi, additional, Blyth, Fiona M., additional, Hirani, Vasant, additional, Le Couteur, David G., additional, Handelsman, David J., additional, Seibel, Markus J., additional, Waite, Louise M., additional, and Stanaway, Fiona F., additional

Published
2022
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98. Inundation prediction in tropical wetlands from JULES-CaMa-Flood global land surface simulations

Author

Marthews, Toby R., Dadson, Simon J., Clark, Douglas B., Blyth, Eleanor M., Hayman, Garry D., Yamazaki, Dai, Becher, Olivia R.E., Martínez-de la Torre, Alberto, Prigent, Catherine, Jiménez, Carlos, Marthews, Toby R., Dadson, Simon J., Clark, Douglas B., Blyth, Eleanor M., Hayman, Garry D., Yamazaki, Dai, Becher, Olivia R.E., Martínez-de la Torre, Alberto, Prigent, Catherine, and Jiménez, Carlos

Abstract

Wetlands play a key role in hydrological and biogeochemical cycles and provide multiple ecosystem services to society. However, reliable data on the extent of global inundated areas and the magnitude of their contribution to local hydrological dynamics remain surprisingly uncertain. Global hydrological models and land surface models (LSMs) include only the most major inundation sources and mechanisms; therefore, quantifying the uncertainties in available data sources remains a challenge. We address these problems by taking a leading global data product on inundation extents (Global Inundation Extent from Multi-Satellites, GIEMS) and matching against predictions from a global hydrodynamic model (Catchment-based Macro-scale Floodplain – CaMa-Flood) driven by runoff data generated by a land surface model (Joint UK Land and Environment Simulator, JULES). The ability of the model to reproduce patterns and dynamics shown by the observational product is assessed in a number of case studies across the tropics, which show that it performs well in large wetland regions, with a good match between corresponding seasonal cycles. At a finer spatial scale, we found that water inputs (e.g. groundwater inflow to wetland) became underestimated in comparison to water outputs (e.g. infiltration and evaporation from wetland) in some wetlands (e.g. Sudd, Tonlé Sap), and the opposite occurred in others (e.g. Okavango) in our model predictions. We also found evidence for an underestimation of low levels of inundation in our satellite-based inundation data (approx. 10 % of total inundation may not be recorded). Additionally, some wetlands display a clear spatial displacement between observed and simulated inundation as a result of overestimation or underestimation of overbank flooding upstream. This study provides timely information on inherent biases in inundation prediction and observation that can contribute to our current ability to make critical predictions of inundation events at both

Published
2022

99. Importance of including soil moisture in drought monitoring over the Brazilian semiarid region: an evaluation using the JULES model, in situ observations, and remote sensing

Author

Zeri, Marcelo, Williams, Karina, Cunha, Ana Paula M.A., Cunha‐Zeri, Gisleine, Vianna, Murilo S., Blyth, Eleanor M., Marthews, Toby R., Hayman, Garry D., Costa, José Maria, Marengo, José A., Alvalá, Regina C.S., Moraes, Osvaldo L.L., Galdos, Marcelo V., Zeri, Marcelo, Williams, Karina, Cunha, Ana Paula M.A., Cunha‐Zeri, Gisleine, Vianna, Murilo S., Blyth, Eleanor M., Marthews, Toby R., Hayman, Garry D., Costa, José Maria, Marengo, José A., Alvalá, Regina C.S., Moraes, Osvaldo L.L., and Galdos, Marcelo V.

Abstract

Soil moisture information is essential to monitoring of the intensity of droughts, the start of the rainy season, planting dates and early warnings of yield losses. We assess spatial and temporal trends of drought over the Brazilian semiarid region by combining soil moisture observations from 360 stations, root zone soil moisture from a leading land surface model, and a vegetation health index from remote sensing. The soil moisture dataset was obtained from the network of stations maintained by the National Center of Monitoring and Early Warning of Natural Disasters (Cemaden), in Brazil. Soil water content at 10 to 35 cm depth, for the period 1979–2018, was obtained from running the JULES land surface model (the Joint UK Land Environment Simulator). The modelled soil moisture was correlated with measurements in the common period of 2015–2018, resulting in an average correlation coefficient of 0.48 across the domain. The standardized soil moisture anomaly (SMA) was calculated for the long-term modelled soil moisture and revealed strong negative values during well-known drought periods in the region, especially during El-Niño years. The performance of SMA in identifying droughts during the first 2 months of the raining and cropping season was similar to the Standardized Precipitation Index (SPI), commonly used for drought assessment: 12–14 events were identified by both indices. Finally, the temporal relationship between both SMA and SPI with the Vegetation Health Index (VHI) was assessed using the cross-wavelet transform. The results indicated lagged correlations of 1 to 1.5 months in the annual scale, suggesting that negative trends in SMA and SPI can be an early warning to yield losses during the growing season. Public policies on drought assessment should consider the combination of multiple drought indices, including soil moisture anomaly.

Published
2022

100. The African SWIFT project: growing science capability to bring about a revolution in weather prediction

Author

Parker, Douglas J., Blyth, Alan M., Woolnough, Steven J., Dougill, Andrew J., Bain, Caroline L., de Coning, Estelle, Diop-Kane, Mariane, Kamga Foamouhoue, Andre, Lamptey, Benjamin, Ndiaye, Ousmane, Ruti, Paolo, Adefisan, Elijah A., Amekudzi, Leonard K., Antwi-Agyei, Philip, Birch, Cathryn E., Cafaro, Carlo, Carr, Hamish, Chanzu, Benard, Clarke, Samantha J., Coskeran, Helen, Danuor, Sylvester K., de Andrade, Felipe M., Diakaria, Kone, Dione, Cheikh, Abdoulahat Diop, Cheikh, Fletcher, Jennifer K., Gaye, Amadou T., Groves, James L., Gudoshava, Masilin, Hartley, Andrew J., Hirons, Linda C., Ibrahim, Ishiyaku, James, Tamora D., Lawal, Kamoru A., Marsham, John H., Mutemi, J.N., Okogbue, Emmanuel Chilekwu, Olaniyan, Eniola, Omotosho, J.B., Portuphy, Joseph, Roberts, Alexander J., Schwendike, Juliane, Segele, Zewdu T., Stein, Thorwald H.M., Taylor, Andrea L., Taylor, Christopher M., Warnaars, Tanya A., Webster, Stuart, Woodhams, Beth J., Youds, Lorraine, Parker, Douglas J., Blyth, Alan M., Woolnough, Steven J., Dougill, Andrew J., Bain, Caroline L., de Coning, Estelle, Diop-Kane, Mariane, Kamga Foamouhoue, Andre, Lamptey, Benjamin, Ndiaye, Ousmane, Ruti, Paolo, Adefisan, Elijah A., Amekudzi, Leonard K., Antwi-Agyei, Philip, Birch, Cathryn E., Cafaro, Carlo, Carr, Hamish, Chanzu, Benard, Clarke, Samantha J., Coskeran, Helen, Danuor, Sylvester K., de Andrade, Felipe M., Diakaria, Kone, Dione, Cheikh, Abdoulahat Diop, Cheikh, Fletcher, Jennifer K., Gaye, Amadou T., Groves, James L., Gudoshava, Masilin, Hartley, Andrew J., Hirons, Linda C., Ibrahim, Ishiyaku, James, Tamora D., Lawal, Kamoru A., Marsham, John H., Mutemi, J.N., Okogbue, Emmanuel Chilekwu, Olaniyan, Eniola, Omotosho, J.B., Portuphy, Joseph, Roberts, Alexander J., Schwendike, Juliane, Segele, Zewdu T., Stein, Thorwald H.M., Taylor, Andrea L., Taylor, Christopher M., Warnaars, Tanya A., Webster, Stuart, Woodhams, Beth J., and Youds, Lorraine

Abstract

Africa is poised for a revolution in the quality and relevance of weather predictions, with potential for great benefits in terms of human and economic security. This revolution will be driven by recent international progress in nowcasting, numerical weather prediction, theoretical tropical dynamics and forecast communication, but will depend on suitable scientific investment being made. The commercial sector has recognized this opportunity and new forecast products are being made available to African stakeholders. At this time, it is vital that robust scientific methods are used to develop and evaluate the new generation of forecasts. The GCRF African SWIFT project represents an international effort to advance scientific solutions across the fields of nowcasting, synoptic and short-range severe weather prediction, subseasonal-to-seasonal (S2S) prediction, user engagement and forecast evaluation. This paper describes the opportunities facing African meteorology and the ways in which SWIFT is meeting those opportunities and identifying priority next steps. Delivery and maintenance of weather forecasting systems exploiting these new solutions requires a trained body of scientists with skills in research and training; modelling and operational prediction; communications and leadership. By supporting partnerships between academia and operational agencies in four African partner countries, the SWIFT project is helping to build capacity and capability in African forecasting science. A highlight of SWIFT is the coordination of three weather-forecasting “Testbeds” – the first of their kind in Africa – which have been used to bring new evaluation tools, research insights, user perspectives and communications pathways into a semi-operational forecasting environment.

Published
2022

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