Search

Your search keyword '"Bozzali, Marco"' showing total 967 results
Start Over Author "Bozzali, Marco"
967 results on '"Bozzali, Marco"'

55. Land/Water Aerobic Activities: Two Sides of the Same Coin. A Comparative Analysis on the Effects in Cognition of Alzheimer's Disease.

Author

Gelfo, Francesca, Petrosini, Laura, Mandolesi, Laura, Landolfo, Eugenia, Caruso, Giulia, Balsamo, Francesca, Bonarota, Sabrina, Bozzali, Marco, Caltagirone, Carlo, and Serra, Laura

Subjects
ALZHEIMER'S disease, AEROBIC exercises, AQUATIC exercises, COGNITION, SUCCESSFUL aging, ANAEROBIC capacity
Abstract

Evidence in the literature indicates that aerobic physical activity may have a protective role in aging pathologies. However, it has not been clarified whether different types of aerobic exercise produce different effects. In particular, these potential differences have not been explored in patients with Alzheimer's disease (AD). The present narrative review has the specific aim of evaluating whether land (walking/running) and water (swimming) aerobic activities exert different effects on cognitive functions and neural correlates in AD patients. In particular, the investigation is carried out by comparing the evidence provided from studies on AD animal models and on patients. On the whole, we ascertained that both human and animal studies documented beneficial effects of land and water aerobic exercise on cognition in AD. Also, the modulation of numerous biological processes is documented in association with structural modifications. Remarkably, we found that aerobic activity appears to improve cognition per se, independently from the specific kind of exercise performed. Aerobic exercise promotes brain functioning through the secretion of molecular factors from skeletal muscles and liver. These molecular factors stimulate neuroplasticity, reduce neuroinflammation, and inhibit neurodegenerative processes leading to amyloid-β accumulation. Additionally, aerobic exercise improves mitochondrial activity, reducing oxidative stress and enhancing ATP production. Aerobic activities protect against AD, but implementing exercise protocols for patients is challenging. We suggest that health policies and specialized institutions should direct increasing attention on aerobic activity as lifestyle modifiable factor for successful aging and age-related conditions. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

56. Are patients with GBA-Parkinson disease good candidates for deep brain stimulation? A longitudinal multicentric study on a large Italian cohort.

Author

Avenali, Micol, Zangaglia, Roberta, Cuconato, Giada, Palmieri, Ilaria, Albanese, Alberto, Alberto Artusi, Carlo, Bozzali, Marco, Calandra-Buonaura, Giovanna, Cavallieri, Francesco, Cilia, Roberto, Cocco, Antoniangela, Cogiamanian, Filippo, Colucci, Fabiana, Cortelli, Pietro, Di Fonzo, Alessio, Eleopra, Roberto, Giannini, Giulia, Imarisio, Alberto, Imbalzano, Gabriele, and Ledda, Claudia

Published
2024
Full Text
View/download PDF

59. Amyloid PET as a marker of normal-appearing white matter early damage in multiple sclerosis: correlation with CSF β-amyloid levels and brain volumes

Author

Pietroboni, Anna M., Carandini, Tiziana, Colombi, Annalisa, Mercurio, Matteo, Ghezzi, Laura, Giulietti, Giovanni, Scarioni, Marta, Arighi, Andrea, Fenoglio, Chiara, De Riz, Milena A., Fumagalli, Giorgio G., Basilico, Paola, Serpente, Maria, Bozzali, Marco, Scarpini, Elio, Galimberti, Daniela, and Marotta, Giorgio

Published
2019
Full Text
View/download PDF

75. Consensus-based care recommendations for adults with myotonic dystrophy type 1

Author

Ashizawa, Tetsuo, Gagnon, Cynthia, Groh, William J., Gutmann, Laurie, Johnson, Nicholas E., Meola, Giovanni, Moxley, Richard, III, Pandya, Shree, Rogers, Mark T., Simpson, Ericka, Angeard, Nathalie, Bassez, Guillaume, Berggren, Kiera N., Bhakta, Deepak, Bozzali, Marco, Broderick, Ann, Byrne, Janice L.B., Campbell, Craig, Cup, Edith, Day, John W., De Mattia, Elisa, Duboc, Denis, Duong, Tina, Eichinger, Katy, Ekstrom, Anne-Berit, van Engelen, Baziel, Esparis, Belen, Eymard, Bruno, Ferschl, Marla, Gadalla, Shahinaz M., Gallais, Benjamin, Goodglick, Todd, Heatwole, Chad, Hilbert, James, Holland, Venessa, Kierkegaard, Marie, Koopman, Wilma J., Lane, Kari, Maas, Daphne, Mankodi, Ami, Mathews, Katherine D., Monckton, Darren G., Moser, David, Nazarian, Saman, Nguyen, Linda, Nopoulos, Peg, Petty, Richard, Phetteplace, Janel, Puymirat, Jack, Raman, Subha, Richer, Louis, Roma, Elisabetta, Sampson, Jacinda, Sansone, Valeria, Schoser, Benedikt, Sterling, Laurie, Statland, Jeffrey, Subramony, S.H., Tian, Cuixia, Trujillo, Careniña, Tomaselli, Gordon, Turner, Chris, Venance, Shannon, Verma, Aparajitha, White, Molly, and Winblad, Stefan

Published
2018
Full Text
View/download PDF

79. Precuneus magnetic stimulation for Alzheimer’s disease: a randomized, sham-controlled trial

Author

Koch, Giacomo, primary, Casula, Elias Paolo, additional, Bonnì, Sonia, additional, Borghi, Ilaria, additional, Assogna, Martina, additional, Minei, Marilena, additional, Pellicciari, Maria Concetta, additional, Motta, Caterina, additional, D’Acunto, Alessia, additional, Porrazzini, Francesco, additional, Maiella, Michele, additional, Ferrari, Clarissa, additional, Caltagirone, Carlo, additional, Santarnecchi, Emiliano, additional, Bozzali, Marco, additional, and Martorana, Alessandro, additional

Published
2022
Full Text
View/download PDF

86. Quantitative MRI Harmonization to Maximize Clinical Impact: The RIN–Neuroimaging Network

Author

Nigri, Anna, Ferraro, Stefania, Gandini Wheeler-Kingshott, Claudia A M, Tosetti, Michela, Redolfi, Alberto, Forloni, Gianluigi, D'Angelo, Egidio, Aquino, Domenico, Biagi, Laura, Bosco, Paolo, Carne, Irene, De Francesco, Silvia, Demichelis, Greta, Gianeri, Ruben, Lagana, Maria Marcella, Micotti, Edoardo, Napolitano, Antonio, Palesi, Fulvia, Pirastru, Alice, Savini, Giovanni, Alberici, Elisa, Amato, Carmelo, Arrigoni, Filippo, Baglio, Francesca, Bozzali, Marco, Castellano, Antonella, Cavaliere, Carlo, Contarino, Valeria Elisa, Ferrazzi, Giulio, Gaudino, Simona, Marino, Silvia, Manzo, Vittorio, Pavone, Luigi, Politi, Letterio S, Roccatagliata, Luca, Rognone, Elisa, Rossi, Andrea, Tonon, Caterina, Lodi, Raffaele, Tagliavini, Fabrizio, Bruzzone, Maria Grazia, and the RIN, – Neuroimaging Network

Subjects
diffusion MRI, neuroimaging, Neurology, QSM, fMRI, harmonization, multisite, quantitative MRI, Neurology (clinical)
Abstract

Neuroimaging studies often lack reproducibility, one of the cardinal features of the scientific method. Multisite collaboration initiatives increase sample size and limit methodological flexibility, therefore providing the foundation for increased statistical power and generalizable results. However, multisite collaborative initiatives are inherently limited by hardware, software, and pulse and sequence design heterogeneities of both clinical and preclinical MRI scanners and the lack of benchmark for acquisition protocols, data analysis, and data sharing. We present the overarching vision that yielded to the constitution of RIN-Neuroimaging Network, a national consortium dedicated to identifying disease and subject-specific in-vivo neuroimaging biomarkers of diverse neurological and neuropsychiatric conditions. This ambitious goal needs efforts toward increasing the diagnostic and prognostic power of advanced MRI data. To this aim, 23 Italian Scientific Institutes of Hospitalization and Care (IRCCS), with technological and clinical specialization in the neurological and neuroimaging field, have gathered together. Each IRCCS is equipped with high- or ultra-high field MRI scanners (i.e., ≥3T) for clinical or preclinical research or has established expertise in MRI data analysis and infrastructure. The actions of this Network were defined across several work packages (WP). A clinical work package (WP1) defined the guidelines for a minimum standard clinical qualitative MRI assessment for the main neurological diseases. Two neuroimaging technical work packages (WP2 and WP3, for clinical and preclinical scanners) established Standard Operative Procedures for quality controls on phantoms as well as advanced harmonized quantitative MRI protocols for studying the brain of healthy human participants and wild type mice. Under FAIR principles, a web-based e-infrastructure to store and share data across sites was also implemented (WP4). Finally, the RIN translated all these efforts into a large-scale multimodal data collection in patients and animal models with dementia (i.e., case study). The RIN-Neuroimaging Network can maximize the impact of public investments in research and clinical practice acquiring data across institutes and pathologies with high-quality and highly-consistent acquisition protocols, optimizing the analysis pipeline and data sharing procedures.

Published
2022
Full Text
View/download PDF

88. Quantitative MRI Harmonization to Maximize Clinical Impact: The RIN???Neuroimaging Network

Author

Nigri, Anna, Ferraro, Stefania, Gandini Wheeler-Kingshott, Claudia A. M., Tosetti, Michela, Redolfi, Alberto, Forloni, Gianluigi, D'Angelo, Egidio, Aquino, Domenico, Biagi, Laura, Bosco, Paolo, Carne, Irene, De Francesco, Silvia, Demichelis, Greta, Gianeri, Ruben, Marcella Lagana, Maria, Micotti, Edoardo, Napolitano, Antonio Giulio, Palesi, Fulvia, Pirastru, Alice, Savini, Giovanni, Alberici, Elisa, Amato, Carmelo, Arrigoni, Filippo Silvio Aldo, Baglio, Francesca, Bozzali, Marco, Castellano, Antonella, Cavaliere, Carlo, Elisa Contarino, Valeria, Ferrazzi, Giulio, Gaudino, Simona, Marino, Silvia, Manzo, Vittorio, Pavone, Luigi, Politi, Letterio S., Roccatagliata, Luca, Rognone, Elisa, Rossi, Andrea, Tonon, Caterina, Lodi, Raffaele, Tagliavini, Fabrizio, Grazia Bruzzone, Maria, Antonio Napolitano, Filippo Arrigoni, Francesca Baglio, Simona Gaudino (ORCID:0000-0003-1681-4343), Andrea Rossi, Nigri, Anna, Ferraro, Stefania, Gandini Wheeler-Kingshott, Claudia A. M., Tosetti, Michela, Redolfi, Alberto, Forloni, Gianluigi, D'Angelo, Egidio, Aquino, Domenico, Biagi, Laura, Bosco, Paolo, Carne, Irene, De Francesco, Silvia, Demichelis, Greta, Gianeri, Ruben, Marcella Lagana, Maria, Micotti, Edoardo, Napolitano, Antonio Giulio, Palesi, Fulvia, Pirastru, Alice, Savini, Giovanni, Alberici, Elisa, Amato, Carmelo, Arrigoni, Filippo Silvio Aldo, Baglio, Francesca, Bozzali, Marco, Castellano, Antonella, Cavaliere, Carlo, Elisa Contarino, Valeria, Ferrazzi, Giulio, Gaudino, Simona, Marino, Silvia, Manzo, Vittorio, Pavone, Luigi, Politi, Letterio S., Roccatagliata, Luca, Rognone, Elisa, Rossi, Andrea, Tonon, Caterina, Lodi, Raffaele, Tagliavini, Fabrizio, Grazia Bruzzone, Maria, Antonio Napolitano, Filippo Arrigoni, Francesca Baglio, Simona Gaudino (ORCID:0000-0003-1681-4343), and Andrea Rossi

Abstract

Neuroimaging studies often lack reproducibility, one of the cardinal features of the scientific method. Multisite collaboration initiatives increase sample size and limit methodological flexibility, therefore providing the foundation for increased statistical power and generalizable results. However, multisite collaborative initiatives are inherently limited by hardware, software, and pulse and sequence design heterogeneities of both clinical and preclinical MRI scanners and the lack of benchmark for acquisition protocols, data analysis, and data sharing. We present the overarching vision that yielded to the constitution of RIN-Neuroimaging Network, a national consortium dedicated to identifying disease and subject-specific in-vivo neuroimaging biomarkers of diverse neurological and neuropsychiatric conditions. This ambitious goal needs efforts toward increasing the diagnostic and prognostic power of advanced MRI data. To this aim, 23 Italian Scientific Institutes of Hospitalization and Care (IRCCS), with technological and clinical specialization in the neurological and neuroimaging field, have gathered together. Each IRCCS is equipped with high- or ultra-high field MRI scanners (i.e., ≥3T) for clinical or preclinical research or has established expertise in MRI data analysis and infrastructure. The actions of this Network were defined across several work packages (WP). A clinical work package (WP1) defined the guidelines for a minimum standard clinical qualitative MRI assessment for the main neurological diseases. Two neuroimaging technical work packages (WP2 and WP3, for clinical and preclinical scanners) established Standard Operative Procedures for quality controls on phantoms as well as advanced harmonized quantitative MRI protocols for studying the brain of healthy human participants and wild type mice. Under FAIR principles, a web-based e-infrastructure to store and share data across sites was also implemented (WP4). Finally, the RIN translated all these ef

Published
2022

Catalog

Books, media, physical & digital resources
See catalog results