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Bisazomethines derived from D,L-camphor, 2-adamantanone, and aliphatic diamines were prepared. The possibility of using bisazomethines as vulcanization accelerators was examined. The physicomechanical parameters of vulcanizates based on SKI-3 and their resistance to thermal oxidative aging were determined. The influence of the bisazomethine structure on the vul canization rate was found. Among the compounds synthesized, N,N′-(propane-1,3-diyl)bis(1,7,7-trimethylbicyclo[2.2.1]heptan-2-imine) shows the best set of vulcanization and operation properties. [ABSTRACT FROM AUTHOR]

A series of 1,3-disubstituted ureas with a phenyl fragment containing fluorine and/or chlorine substituents in different positions were synthesized with yields of 33–80%. 1-Isocyanatoadamantane was prepared for the first time by the reaction of diphenylphosphoryl azide with (adamantan-1-yl)carboxylic acid in a yield of 85%. [ABSTRACT FROM AUTHOR]

Carboxamides and carbamoyl oximes containing both adamantyl and 3,6-diazahomoadamantyl fragments were synthesized. The reactions proceed in mild conditions and in high yields. The synthesized compounds are promising as soluble epoxide hydrolase inhibitors. [ABSTRACT FROM AUTHOR]

(1S)-1-Isocyanato-4,7,7-trimethyl-2-oxabicyclo[2.2.1]heptan-3-one and 2-isocyanatobicyclo[2.2.1]-hept-5-ene were prepared by the Curtius rearragement reaction from the corresponding carboxylic acids. The synthesized isocyanates were used to synthesize, in high yields of 74–93%, bioisosteric 1,3-disubstituted ureas as potential human soluble epoxide hydrolase inhibitors. [ABSTRACT FROM AUTHOR]

To assess the effect of the lipophilicity of different parts of urea molecules on their activity as soluble epoxide hydrolase inhibitors, a series of 1,3-disubstituted ureas containing cycloheptane and bicyclo-[2.2.1]heptane fragments were prepared by the reaction of isocyanates with corresponding amines in 78–94% yields. [ABSTRACT FROM AUTHOR]

The reaction of 1,3-dehydroadamantane with aliphatic aldehydes involves the Ca-H bond and forms hardly accessible branched 2-(1-adamantyl)alkylaldehydes in one stage in a yield of 60-78%. It is found that 2-(1-adamantyl)alkylaldehydes are prone to oligomerization. The reaction of 2-(1-adamantyl)-alkylaldehydes with 2,4-dinitrophenylhydrazine gave the corresponding hydrazones in a yield of 84-98%. [ABSTRACT FROM AUTHOR]