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Real-time 6 DOF localization of bronchoscopes is crucial for enhancing intervention quality. However, current vision-based technologies struggle to balance between generalization to unseen data and computational speed. In this study, we propose a Depth-based Dual-Loop framework for real-time Visually Navigated Bronchoscopy (DD-VNB) that can generalize across patient cases without the need of re-training. The DD-VNB framework integrates two key modules: depth estimation and dual-loop localization. To address the domain gap among patients, we propose a knowledge-embedded depth estimation network that maps endoscope frames to depth, ensuring generalization by eliminating patient-specific textures. The network embeds view synthesis knowledge into a cycle adversarial architecture for scale-constrained monocular depth estimation. For real-time performance, our localization module embeds a fast ego-motion estimation network into the loop of depth registration. The ego-motion inference network estimates the pose change of the bronchoscope in high frequency while depth registration against the pre-operative 3D model provides absolute pose periodically. Specifically, the relative pose changes are fed into the registration process as the initial guess to boost its accuracy and speed. Experiments on phantom and in-vivo data from patients demonstrate the effectiveness of our framework: 1) monocular depth estimation outperforms SOTA, 2) localization achieves an accuracy of Absolute Tracking Error (ATE) of 4.7 $\pm$ 3.17 mm in phantom and 6.49 $\pm$ 3.88 mm in patient data, 3) with a frame-rate approaching video capture speed, 4) without the necessity of case-wise network retraining. The framework's superior speed and accuracy demonstrate its promising clinical potential for real-time bronchoscopic navigation.

Bronchoscopy plays a significant role in the early diagnosis and treatment of lung diseases. This process demands physicians to maneuver the flexible endoscope for reaching distal lesions, particularly requiring substantial expertise when examining the airways of the upper lung lobe. With the development of artificial intelligence and robotics, reinforcement learning (RL) method has been applied to the manipulation of interventional surgical robots. However, unlike human physicians who utilize multimodal information, most of the current RL methods rely on a single modality, limiting their performance. In this paper, we propose BronchoCopilot, a multimodal RL agent designed to acquire manipulation skills for autonomous bronchoscopy. BronchoCopilot specifically integrates images from the bronchoscope camera and estimated robot poses, aiming for a higher success rate within challenging airway environment. We employ auxiliary reconstruction tasks to compress multimodal data and utilize attention mechanisms to achieve an efficient latent representation of this data, serving as input for the RL module. This framework adopts a stepwise training and fine-tuning approach to mitigate the challenges of training difficulty. Our evaluation in the realistic simulation environment reveals that BronchoCopilot, by effectively harnessing multimodal information, attains a success rate of approximately 90\% in fifth generation airways with consistent movements. Additionally, it demonstrates a robust capacity to adapt to diverse cases.

This article demonstrates a new kind of programmable logic for the representation of an integer that can be used for the programmable Josephson voltage standard. It can enable the numbers of junctions in most bits to be variable integer values, which is different from normal binary logic or ternary logic. Consequently, missing junctions due to superconducting short circuits can be tolerated under this logic. This logic can also have nearly the same segmentation efficiency as ternary logic. The completeness of the sequences using this logic is proven by the recursive method in mathematics in this paper. After that, a new algorithm for the representation of integers is presented according to the proven process, and an analysis of the number of fault-tolerant junctions for each bit is provided. Although the first and second bits are not tolerant to missing junctions, bits beyond these can tolerate one to hundreds of missing junctions. Due to the non-fixed multiples between the bits of the sequence, this logic is called non-integer-multiple logic. Finally, the design and fabrication of a 3 V programmable Josephson junction array using this logic are described, and the measurements and analysis of the characteristic parameters are presented.

Localizing the bronchoscope in real time is essential for ensuring intervention quality. However, most existing methods struggle to balance between speed and generalization. To address these challenges, we present BronchoTrack, an innovative real-time framework for accurate branch-level localization, encompassing lumen detection, tracking, and airway association.To achieve real-time performance, we employ a benchmark lightweight detector for efficient lumen detection. We are the first to introduce multi-object tracking to bronchoscopic localization, mitigating temporal confusion in lumen identification caused by rapid bronchoscope movement and complex airway structures. To ensure generalization across patient cases, we propose a training-free detection-airway association method based on a semantic airway graph that encodes the hierarchy of bronchial tree structures.Experiments on nine patient datasets demonstrate BronchoTrack's localization accuracy of 85.64 \%, while accessing up to the 4th generation of airways.Furthermore, we tested BronchoTrack in an in-vivo animal study using a porcine model, where it successfully localized the bronchoscope into the 8th generation airway.Experimental evaluation underscores BronchoTrack's real-time performance in both satisfying accuracy and generalization, demonstrating its potential for clinical applications.

Traditional rigid endoscopes have challenges in flexibly treating tumors located deep in the brain, and low operability and fixed viewing angles limit its development. This study introduces a novel dual-segment flexible robotic endoscope MicroNeuro, designed to perform biopsies with dexterous surgical manipulation deep in the brain. Taking into account the uncertainty of the control model, an image-based visual servoing with online robot Jacobian estimation has been implemented to enhance motion accuracy. Furthermore, the application of model predictive control with constraints significantly bolsters the flexible robot's ability to adaptively track mobile objects and resist external interference. Experimental results underscore that the proposed control system enhances motion stability and precision. Phantom testing substantiates its considerable potential for deployment in neurosurgery., Comment: Accepted by IEEE International Conference on Robotics and Automation (ICRA) 2024, 7 pages, 9 figures

Controllable layout generation refers to the process of creating a plausible visual arrangement of elements within a graphic design (e.g., document and web designs) with constraints representing design intentions. Although recent diffusion-based models have achieved state-of-the-art FID scores, they tend to exhibit more pronounced misalignment compared to earlier transformer-based models. In this work, we propose the $\textbf{LA}$yout $\textbf{C}$onstraint diffusion mod$\textbf{E}$l (LACE), a unified model to handle a broad range of layout generation tasks, such as arranging elements with specified attributes and refining or completing a coarse layout design. The model is based on continuous diffusion models. Compared with existing methods that use discrete diffusion models, continuous state-space design can enable the incorporation of differentiable aesthetic constraint functions in training. For conditional generation, we introduce conditions via masked input. Extensive experiment results show that LACE produces high-quality layouts and outperforms existing state-of-the-art baselines., Comment: Accepted by ICLR 2024

Occasional deadline misses are acceptable for soft real-time systems. Quantifying probabilistic and deterministic characteristics of deadline misses is therefore essential to ensure that deadline misses indeed happen only occasionally. This is supported by recent research activities on probabilistic worst-case execution time, worst-case deadline failure probability, the maximum number of deadline misses, upper bounds on the deadline miss probability, and the deadline miss rate. This paper focuses on the deadline miss rate of a periodic soft real-time task in the long run. Our model assumes that this soft real-time task has an arbitrary relative deadline and that a job can still be executed after a deadline-miss until a dismiss point. This model generalizes the existing models that either dismiss a job immediately after its deadline miss or never dismiss a job. We provide mathematical notation on the convergence of the deadline miss rate in the long run and essential properties to calculate the deadline miss rate. Specifically, we use a Markov chain to model the execution behavior of a periodic soft real-time task. We present the required ergodicity property to ensure that the deadline miss rate in the long run is described by a stationary distribution.

The complex interplay of spin frustration and quantum fluctuations in low-dimensional quantum materials leads to a variety of intriguing phenomena. This research focuses on a detailed analysis of the magnetic behavior exhibited by NdZnPO, a bilayer spin-1/2 triangular lattice antiferromagnet. The investigation employs magnetization, specific heat, and powder neutron scattering measurements. At zero field, a long-range magnetic order is observed at $T_{\rm N}=1.64~\rm K$. Powder neutron diffraction experiments show the Ising-like magnetic moments along the $c$-axis, revealing a stripe-like magnetic structure with three equivalent magnetic propagation vectors. Application of a magnetic field along the $c$-axis suppresses the antiferromagnetic order, leading to a fully polarized ferromagnetic state above $B_{\rm c}=4.5~\rm T$. This transition is accompanied by notable enhancements in the nuclear Schottky contribution. Moreover, the absence of spin frustration and expected field-induced plateau-like phases are remarkable observations. Detailed calculations of magnetic dipolar interactions revealed complex couplings reminiscent of a honeycomb lattice, suggesting the potential emergence of Kitaev-like physics within this system. This comprehensive study of the magnetic properties of NdZnPO highlights unresolved intricacies, underscoring the imperative for further exploration to unveil the underlying governing mechanisms., Comment: 11 pages, 6 figures

This paper investigates covert communications in an integrated sensing and communications system, where a dual-functional base station (called Alice) covertly transmits signals to a covert user (called Bob) while sensing multiple targets, with one of them acting as a potential watcher (called Willie) and maliciously eavesdropping on legitimate communications. To shelter the covert communications, Alice transmits additional dual-functional artificial noise (DFAN) with a varying power not only to create uncertainty at Willie's signal reception to confuse Willie but also to sense the targets simultaneously. Based on this framework, the weighted sum of the sensing beampattern means square error (MSE) and cross correlation is minimized by jointly optimizing the covert communication and DFAN signals subject to the minimum covert rate requirement. The robust design considers both cases of imperfect Willie's CSI (WCSI) and statistical WCSI. Under the worst-case assumption that Willie can adaptively adjust the detection threshold to achieve the best detection performance, the minimum detection error probability (DEP) at Willie is analytically derived in the closed-form expression. The formulated covertness constrained optimization problems are tackled by a feasibility-checking based difference-of-convex relaxation (DC) algorithm utilizing the S-procedure, Bernstein-type inequality, and the DC method. Simulation results validate the feasibility of the proposed scheme and demonstrate the covertness performance gains achieved by our proposed design over various benchmarks.

A novel dynamic hybrid beamforming architecture is proposed to achieve the spatial multiplexing-power consumption tradeoff for near-field multiple-input multiple-output (MIMO) networks, where each radio frequency (RF) chain is connected to each antenna using a couple of independent phase shifters to reduce the number of required RF chains. Based on this architecture, an optimization problem is formulated that maximizes the sum of achievable rates while minimizing the hardware power consumption. Both continuous and discrete phase shifters are considered. 1) For continuous phase shifters, a weighted minimum mean-square error-based two-stage (WMMSE-TS) algorithm is proposed, where the same performance as the optimal fully-digital beamformer can be achieved by the proposed hybrid beamformer even if the number of RF chains equals the number of data streams. 2) For discrete phase shifters, a penalty-based layered iterative (PLI) algorithm is proposed. The closed-form analog and baseband digital beamformers are derived in each iteration. Simulation results demonstrate that: 1) the proposed dynamic beamforming architecture outperforms the conventional fixed hybrid beamforming architecture in terms of spatial multiplexing-power consumption tradeoff, and 2) the proposed algorithms achieve better performance than the other baseline schemes., Comment: 14 pages

Shock breakout emission is light that arises when a shockwave, generated by core-collapse explosion of a massive star, passes through its outer envelope. Hitherto, the earliest detection of such a signal was at several hours after the explosion, though a few others had been reported. The temporal evolution of early light curves should reveal insights into the shock propagation, including explosion asymmetry and environment in the vicinity, but this has been hampered by the lack of multiwavelength observations. Here we report the instant multiband observations of a type II supernova (SN 2023ixf) in the galaxy M101 (at a distance of 6.85+/-0.15 Mpc), beginning at about 1.4 hours after the explosion. The exploding star was a red supergiant with a radius of about 440 solar radii. The light curves evolved rapidly, on timescales of 1-2 hours, and appeared unusually fainter and redder than predicted by models within the first few hours, which we attribute to an optically thick dust shell before it was disrupted by the shockwave. We infer that the breakout and perhaps the distribution of the surrounding dust were not spherically symmetric., Comment: 32 pages, 9 figures, and 3 tables. Online publication in Nature (Dec. 13th 2023)

Based on the nonequilibrium Green's function (NEGF), we develop a quantum nonlinear theory to study time-dependent ac transport properties in the low frequency and nonlinear bias voltage regimes. By expanding NEGF in terms of time to the linear order in Wigner representation, we can explicitly include the time-dependent self-consistent Coulomb interaction induced by external ac bias. Hence this theory automatically satisfies two basic requirements, i.e., current conservation and gauge invariance. Within this theory, the nonlinear ac current can be evaluated at arbitrarily large bias voltages under the low frequency limit. In addition, we obtain the expression of time-dependent current under the wide band limit and derive the relation between the nonlinear electrochemical capacitance and the bias voltage, which are very useful in predicting the dynamical properties of nanoelectronic devices. This quantum theory can be directly combined with density functional theory to investigate time-dependent ac transport from first-principles calculation.

The Landau-Lifshitz-Gilbert (LLG) equation is widely used to describe magnetization dynamics. We develop a unified framework of the microscopic LLG equation based on the nonequilibrium Green's function formalism. We present a unified treatment for expressing the microscopic LLG equation in several limiting cases, including the adiabatic, inertial, and nonadiabatic limits with respect to the precession frequency for a magnetization with fixed magnitude, as well as the spatial adiabatic limit for the magnetization with slow variation in both its magnitude and direction. The coefficients of those terms in the microscopic LLG equation are explicitly expressed in terms of nonequilibrium Green's functions. As a concrete example, this microscopic theory is applied to simulate the dynamics of a magnetic Skyrmion driven by quantum parametric pumping. Our work provides a practical formalism of the microscopic LLG equation for exploring magnetization dynamics.

Radar has stronger adaptability in adverse scenarios for autonomous driving environmental perception compared to widely adopted cameras and LiDARs. Compared with commonly used 3D radars, the latest 4D radars have precise vertical resolution and higher point cloud density, making it a highly promising sensor for autonomous driving in complex environmental perception. However, due to the much higher noise than LiDAR, manufacturers choose different filtering strategies, resulting in an inverse ratio between noise level and point cloud density. There is still a lack of comparative analysis on which method is beneficial for deep learning-based perception algorithms in autonomous driving. One of the main reasons is that current datasets only adopt one type of 4D radar, making it difficult to compare different 4D radars in the same scene. Therefore, in this paper, we introduce a novel large-scale multi-modal dataset featuring, for the first time, two types of 4D radars captured simultaneously. This dataset enables further research into effective 4D radar perception algorithms.Our dataset consists of 151 consecutive series, most of which last 20 seconds and contain 10,007 meticulously synchronized and annotated frames. Moreover, our dataset captures a variety of challenging driving scenarios, including many road conditions, weather conditions, nighttime and daytime with different lighting intensities and periods. Our dataset annotates consecutive frames, which can be applied to 3D object detection and tracking, and also supports the study of multi-modal tasks. We experimentally validate our dataset, providing valuable results for studying different types of 4D radars. This dataset is released on https://github.com/adept-thu/Dual-Radar.

Learning to navigate to an image-specified goal is an important but challenging task for autonomous systems. The agent is required to reason the goal location from where a picture is shot. Existing methods try to solve this problem by learning a navigation policy, which captures semantic features of the goal image and observation image independently and lastly fuses them for predicting a sequence of navigation actions. However, these methods suffer from two major limitations. 1) They may miss detailed information in the goal image, and thus fail to reason the goal location. 2) More critically, it is hard to focus on the goal-relevant regions in the observation image, because they attempt to understand observation without goal conditioning. In this paper, we aim to overcome these limitations by designing a Fine-grained Goal Prompting (FGPrompt) method for image-goal navigation. In particular, we leverage fine-grained and high-resolution feature maps in the goal image as prompts to perform conditioned embedding, which preserves detailed information in the goal image and guides the observation encoder to pay attention to goal-relevant regions. Compared with existing methods on the image-goal navigation benchmark, our method brings significant performance improvement on 3 benchmark datasets (i.e., Gibson, MP3D, and HM3D). Especially on Gibson, we surpass the state-of-the-art success rate by 8% with only 1/50 model size. Project page: https://xinyusun.github.io/fgprompt-pages, Comment: Accepted by NeurIPS 2023

We present results from a pilot experiment to measure if machine recommendations can debias human perceptual biases in visualization tasks. We specifically studied the ``pull-down'' effect, i.e., people underestimate the average position of lines, for the task of estimating the ensemble average of data points in line charts. These line charts can show for example temperature or precipitation in 12 months. Six participants estimated ensemble averages with or without an AI assistant. The assistant, when available, responded at three different speeds to assemble the conditions of a human collaborator who may delay his or her responses. Our pilot study showed that participants were faster with AI assistance in ensemble tasks, compared to the baseline without AI assistance. Although ``pull-down'' biases were reduced, the effect of AI assistance was not statistically significant. Also, delaying AI responses had no significant impact on human decision accuracy. We discuss the implications of these preliminary results for subsequent studies., Comment: This paper was accepted IEEE VIS 2023 VISxVISION Workshop