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457 results on '"Chen, Yinyin"'

56. Visual Exploration of Virtual Lives in Multiplayer Online Games

Author

Liu, Zhiqi, Shen, Yandi, Lu, Junhua, Kong, Dingke, Chen, Yinyin, He, Jingxuan, Liu, Shu, Qi, Ye, Chen, Wei, Hutchison, David, Series editor, Kanade, Takeo, Series editor, Josef, Kittler, Series editor, Kleinberg, Jon M., Series editor, Mattern, Friedemann, Series editor, Mitchell, John C., Series editor, Naor, Moni, Series editor, Pandu Rangan, C., Series editor, Steffen, Bernhard, Series editor, Terzopoulos, Demetri, Series editor, Tygar, Doug, Series editor, Weikum, Gerhard, Series editor, El Rhalibi, Abdennour, editor, Tian, Feng, editor, Pan, Zhigeng, editor, and Liu, Baoquan, editor

Published
2016
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60. Learning Topic Models: Identifiability and Finite-Sample Analysis.

Author

Chen, Yinyin, He, Shishuang, Yang, Yun, and Liang, Feng

Subjects
*MAXIMUM likelihood statistics, *LATENT variables, *COMPUTATIONAL geometry, *STATISTICAL accuracy
Abstract

Topic models provide a useful text-mining tool for learning, extracting, and discovering latent structures in large text corpora. Although a plethora of methods have been proposed for topic modeling, lacking in the literature is a formal theoretical investigation of the statistical identifiability and accuracy of latent topic estimation. In this article, we propose a maximum likelihood estimator (MLE) of latent topics based on a specific integrated likelihood that is naturally connected to the concept, in computational geometry, of volume minimization. Our theory introduces a new set of geometric conditions for topic model identifiability, conditions that are weaker than conventional separability conditions, which typically rely on the existence of pure topic documents or of anchor words. Weaker conditions allow a wider and thus potentially more fruitful investigation. We conduct finite-sample error analysis for the proposed estimator and discuss connections between our results and those of previous investigations. We conclude with empirical studies employing both simulated and real datasets. for this article are available online. [ABSTRACT FROM AUTHOR]

Published
2023
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61. REPERFUSION HEMORRHAGE COMPROMISES MYOCARDIAL SALVAGE

Author

Liu, Ting, primary, Howarth, Andrew G., additional, Chen, Yinyin, additional, Yang, Hsin-Jung, additional, Tang, Richard, additional, Dey, Damini, additional, Slomka, Piotr, additional, Wood, John, additional, Berman, Daniel S., additional, Kumar, Andreas, additional, and Dharmakumar, Rohan, additional

Published
2023
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63. Pyrazole–pyridine–pyrazole (NNN) ruthenium(II) complex catalyzed acceptorless dehydrogenation of alcohols to aldehydes.

Author

Chen, Yinyin, Cui, Tianhua, Chen, Hua, li Zheng, Xue, Fu, Haiyan, and Li, Ruixiang

Subjects
*RUTHENIUM compounds, *RUTHENIUM, *ALDEHYDES, *ALCOHOL, *SUSTAINABLE chemistry, *DEHYDROGENATION, *CONDENSATION reactions
Abstract

A new series of cationic ruthenium(II) complexes, [RuCl(PPh3)2(κ3-NNN-L1)]Cl (1), [RuH(PPh3)2(κ3-NNN-L2)]Cl (2), and [RuH(PPh3)2(κ3-NNN-L3)]Cl (3), bearing a 2,6-bis (1-R-5-methyl-pyrazol-3-yl) pyridine ligand (L1: R = H, L2: R = C6H4-p-CF3, L3: R = C6H4-p-OCH3), were synthesized and characterized with NMR, HRMS, and single-crystal X-ray diffraction. Their catalytic application was investigated in the acceptorless dehydrogenation (AD) of primary alcohols. Complex 1 outperformed 2 and 3 in terms of the selectivity towards the aldehydes, and provided the aldehydes with a yield of up to 99%, with good functional group tolerance under mild conditions. In addition, the only by-product of the reaction was dihydrogen, which can be collected as clean energy, and the reaction meets the requirements of environment-friendly chemistry. Complex 1 also proved to be a promising catalyst in the sequential AD/condensation reaction between the primary and secondary alcohols, affording α,β-unsaturated ketones in moderate to good selectivity. [ABSTRACT FROM AUTHOR]

Published
2023
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64. Efficacy and safety of colistin sulfate in the treatment of infections caused by carbapenem-resistant organisms: a multicenter retrospective cohort study

Author

Peng, Danyang, primary, Zhang, Fan, additional, Chen, Yinyin, additional, Zhao, Congyi, additional, Niu, Jingjing, additional, Yang, Jianxu, additional, Li, Zhifeng, additional, Chen, Chao, additional, Qiu, Shi, additional, Zhang, Huifeng, additional, Qin, Bingyu, additional, Fang, Xiang, additional, Guo, Suping, additional, Liu, Ying, additional, and Shao, Huanzhang, additional

Published
2023
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88. Mn3O4Nanozyme Loaded Thermosensitive PDLLA-PEG-PDLLA Hydrogels for the Treatment of Inflammatory Bowel Disease

Author

Yang, Zhongke, Zhou, Xuan, Wang, Lidan, Guo, Hai, Han, Ming, Guo, Hongrui, Chen, Yinyin, Wu, Aimin, Li, Hongyan, Chen, Shun, Xie, Yue, and Wang, Xianxiang

Abstract

When reactive oxygen species (ROS) accumulate in the body, they can lead to inflammatory bowel disease (IBD) through their oxidative damages to DNA, proteins, and lipids. In this study, a thermosensitive hydrogel-based nanozyme was developed to treat IBD. We first synthesized a manganese oxide (Mn3O4) nanozyme with multienzyme activity followed by physically loading with a thermosensitive hydrogel poly(d,l-lactide)-poly(ethylene glycol)-poly(d,l-lactide)-based triblock copolymer (PDLLA-PEG-PDLLA). Then, a mouse model based on the inducement of dextran sulfate sodium (DSS) was built to assess the ROS targeting, scavenging, as well as anti-inflammatory ability of Mn3O4nanozymes-loaded PDLLA-PEG-PDLLA (MLPPP). Because of the sharp gelation behavior of PDLLA-PEG-PDLLA in body temperature, the MLPPP nanozyme can easily target the inflamed colon after colorectal administration. Following the formation of a physical protection barrier and sustained release of manganese oxide nanozymes that had diverse enzymatic activities and can effectively scavenge ROS, the administration of the MLPPP nanozyme had a high efficacy for treating colitis mice; importantly, after the treatment with this novel nanoformulation, the levels of the pathological indicators in colons as well as in sera of colitis mice were even comparable to healthy mice. Therefore, the MLPPP nanozyme has a potential application for nanotherapy of IBD and would have great clinical translation prospects.

Published
2023
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100. Additional file 1 of Quantification of myocardial hemorrhage using T2* cardiovascular magnetic resonance at 1.5T with ex-vivo validation

Author

Chen, Yinyin, Ren, Daoyuan, Guan, Xingmin, Yang, Hsin-Jung, Liu, Ting, Tang, Richard, Ho, Hao, Jin, Hang, Zeng, Mengsu, and Dharmakumar, Rohan

Abstract

Additional file 1: Figure S1. Flow Diagram for Patient Studies. Figure S2. Flow Diagram for Pre-clinical Studies. Table S1. Comparison of correlation coefficients and slopes between T2* and IMH-Fe concentration between and within subject-specific, and absolute-threshold based approaches. Figure S3. Relationship between IMH Volume, T2* Value, and Functional LV Remodeling Using Subject-specific, and Absolute-threshold Based Approaches.

Published
2021
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