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530 results on '"Davey T"'

57. Equine grass sickness, but not botulism, causes autonomic and enteric neurodegeneration and increases soluble N‐ethylmaleimide‐sensitive factor attachment receptor protein expression within neuronal perikarya

Author

McGorum, B. C., primary, Scholes, S., additional, Milne, E. M., additional, Eaton, S. L., additional, Wishart, T. M., additional, Poxton, I. R., additional, Moss, S., additional, Wernery, U., additional, Davey, T., additional, Harris, J. B., additional, and Pirie, R. S., additional

Published
2016
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76. Applying Site-Specific Resource Assessment: Emulation of Representative EMEC seas in the FloWave Facility.

Author

Draycott, S., Davey, T., Ingram, D. M., Lawrence, J., Day, A., and Johanning, L.

Abstract

The article discusses research which examined the process of classifying, generating and measuring the representative directional spectra in FloWave facility at the University of Edinburgh. Topics discussed include the use of site-specific buoy data to improve the realism of wave tank tests and site classification methodology.

Published
2015

78. Natural bone collagen scaffold combined with autologous enriched bone marrow cells for induction of osteogenesis in an ovine spinal fusion model

Author

Qian, Y., Lin, Z., Chen, J., Fan, Y., Davey, T., Cake, M., Day, R., Dai, K., Xu, J., Zheng, M., Qian, Y., Lin, Z., Chen, J., Fan, Y., Davey, T., Cake, M., Day, R., Dai, K., Xu, J., and Zheng, M.

Abstract

Autologous bone graft, the standard of bone grafting in achieving spinal fusion, is associated with several limitations and complications. The use of bone marrow cells (BMCs) as a potential cell source for spinal fusion, combined with a suitable scaffold to promote bone formation, may be a better choice. The aims of this study were to evaluate the efficacy of natural bone collagen scaffold (NBCS) combined with autologous-enriched BMCs for induction of osteogenesis in vitro and in vivo. Ovine-enriched BMCs were co-cultured with NBCS for 1, 2, 3, and 4 weeks to investigate whether NBCS would support the population expansion and differentiation of enriched BMCs. Using an ovine interbody fusion model, NBCS seeded with autologous enriched BMCs was implanted into the lumbar disc space. Fusion outcomes were compared with the use of the autograft, NBCS without BMCs, and BMCs without NBCS. In vitro results demonstrated that NBCS facilitated the population expansion and differentiation of ovine-enriched BMCs, promoting the expression of collagen type I and the formation of a mineralized matrix. The use of NBCS combined with enriched BMCs in vivo enhanced the spinal fusion rate (6 of 6 at 10 week) (p<0.05), the biomechanical stiffness of fusion masses, and bone volume at the fusion site (p<0.05). Histological findings also revealed that a combination of NBCS and BMCs induced new bone formation that integrated well with host bone tissue. In conclusion, NBCS is an effective scaffold that supports ovine-enriched BMCs. The combination of NBCS and BMCs may be a useful alternative for autograft in induction of spinal fusion.

Published
2009

100. Canine nasal aspergillosis: Results of treatment using clotrimazole as a topical agent

Author

Burbidge, H.M., Clark, W.T., Read, R.A., Labuc, R., Davey, T., Broome, C., Burbidge, H.M., Clark, W.T., Read, R.A., Labuc, R., Davey, T., and Broome, C.

Abstract

This case series describes the response of canine nasal aspergillosis to topical clotrimazole treatment in 11 dogs. The antifungal agent was administered to affected dogs by one of three methods: A) twice daily administration for 10 days via surgically implanted, indwelling catheters into the frontal sinuses and nasal cavity (three dogs); B) a single treatment consisting of one-hour contact-time with the drug immediately following catheter placement (three dogs); and C) non-invasive intranasal single infusion via the nostrils with a one-hour contact time (five dogs). All dogs were assessed for recurrence of the disease (follow-up time range two to 24 months). In one of the three dogs and two of the three dogs treated by method A and B respectively, clinical signs of aspergillosis recurred. However, four of the five dogs treated by method C were free of disease at the fourth week post-treatment assessment. The remaining dog required one further intranasal infusion before complete resolution occurred. From this small case series, it appears that non-invasive intranasal infusion of topical clotrimazole appears to be an effective treatment for canine nasal Aspergillus infections. This simple non-surgical treatment can be easily performed by veterinarians in general practice.

Published
1997

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