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72 results on '"Dickman, Paul S."'

62. Long bone ossifying fibromas.

Author

Goergen, Thomas G., Dickman, Paul S., Resnick, Donald, Saltzstein, Sidney L., O'Dell, Charles W., Akeson, Wayne H., Goergen, T G, Dickman, P S, Resnick, D, Saltzstein, S L, O'Dell, C W, and Akeson, W H

Published
1977
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64. A Sibship With Hypokalemic Alkalosis and Renal Proximal Tubulopathy

Author

Güllner, Hans-Georg, Bartter, Frederic C., Gill, John R., Dickman, Paul S., Wilson, Curtis B., and Tiwari, Jawahar L.

Abstract

• A new syndrome, characterized by hypokalemic alkalosis, hyperreninemia, aldosterone, high urinary prostaglandin E2 excretion, normal BP, and resistance of BP to angiotensin II is described in three of four siblings. Histologic examination of tissue obtained by biopsy from the kidneys showed an intense staining of the proximal tubular cells, as well as an extreme hypertrophy of the proximal tubular basement membranes, features that previously have not been observed. On electron microscopic examination, the characteristic changes of the tubular cells consisted of very dense cytoplasm, compact mitochondria, and pyknotic nuclei. In contrast to Bartter's syndrome, the juxtaglomerular apparatus were of normal appearance. Glomerular filtration rate and renal plasma flow were within normal limits. Fractional distal delivery of proximal tubular solute and fractional chloride reabsorption in the thick ascending limb of the loop of Henle were normal. The findings of a genetic linkage between the syndrome and the major histocompatibility system suggests that this familial tubulopathy is an inherited disorder.(Arch Intern Med 1983;143:1534-1540)

Published
1983
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69. Editorial Interpretation of pediatric allograft endomyocardial biopsies: A new approach.

Author

Dickman, Paul S.

Subjects
*BIOPSY, *HEART transplantation, *TRANSPLANTATION of organs, tissues, etc. in children, *GRAFT rejection, *TACROLIMUS, *CYCLOSPORINE
Abstract

Editorial. Discusses the practice of endomyocardial biopsies for the evaluation of cardiac transplant status in children. Difference in the incidence of cellular rejection between patients receiving tacrolimus and cyclosporine; Factors considered in the evaluation of cardiac biopsies; Rate of rejection diagnosed in endomyocardial biopsies.

Published
2004
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71. The Association of Epstein–Barr Virus with Smooth-Muscle Tumors Occurring after Organ Transplantation.

Author

Lee, Elsie S., Locker, Joseph, Nalesnik, Michael, Reyes, Jorge, Jaffe, Ronald, Alashari, Mouied, Nour, Bakr, Tzakis, Andreas, and Dickman, Paul S.

Subjects
*EPSTEIN-Barr virus, *SMOOTH muscle tumors, *TRANSPLANTATION of organs, tissues, etc., *IMMUNOSUPPRESSION, *JUVENILE diseases
Abstract

Background: Epstein–Barr virus (EBV) has been associated with nasopharyngeal carcinoma, some lymphomas, and lymphoproliferative disease after organ transplantation. Many lymphoproliferative tumors that occur after transplantation are clonal, a property that classifies them as neoplastic. Clonality can be determined by analysis of the extrachromosomal circular DNA episomes produced by EBV infection. Methods: We describe three young children in whom smooth-muscle tumors developed 18 months to 5 years after liver transplantation with immunosuppression. We examined the tumors by microscopy and with immunohistochemical studies and molecular genetic analyses of the EBV DNA. Results: The tumors were composed of spindle cells with smooth-muscle features and resembled those described in patients with the acquired immunodeficiency syndrome. Immunohistochemical analysis was negative for EBV latent membrane protein and EBV receptor (CD21), but positive for EBV nuclear antigen 2. In situ hybridization revealed nuclear EBV sequences, and molecular genetic analysis showed the EBV genome to be clonal in all three patients. Conclusions: Smooth-muscle tumors that developed after organ transplantation contained clonal EBV, suggesting that the virus has a role in the development of these neoplastic lesions. (N Engl J Med 1995;332:19-25.) [ABSTRACT FROM AUTHOR]

Published
1995
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72. Thoraco-abdominal enteric duplication cyst in association with neurenteric cyst, axial skeletal anomalies, and malrotation.

Author

Bui T, Bankhart MF, Mandell GA, Dickman PS, and Bae JO

Abstract

We report a case of a 2-year old boy with cervicothoracic deformity with vertebral rib anomalies, neurenteric cyst, separate thoracoabominal enteric duplication cyst, concurrent intestinal malrotation, and dextroposition of the heart. This combination of abnormalities is very rare. When these lesions are suspected, the patient must be investigated carefully. This case is presented to show the importance of cross-sectional imaging (MR and CT) for surgical planning.

Published
2015
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