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229 results on '"Dulski, K."'

51. The SIDDHARTA-2 Veto-2 system for X-ray spectroscopy of kaonic atoms at DAΦNE

Author

Tüchler, M., primary, Amsler, C., additional, Bazzi, M., additional, Bosnar, D., additional, Bragadireanu, M., additional, Cargnelli, M., additional, Carminati, M., additional, Clozza, A., additional, Deda, G., additional, Del Grande, R., additional, De Paolis, L., additional, Dulski, K., additional, Fabbietti, L., additional, Fiorini, C., additional, Friščić, I., additional, Guaraldo, C., additional, Iliescu, M., additional, Iwasaki, M., additional, Khreptak, A., additional, Manti, S., additional, Marton, J., additional, Miliucci, M., additional, Moskal, P., additional, Napolitano, F., additional, Niedźwiecki, S., additional, Ohnishi, H., additional, Piscicchia, K., additional, Sada, Y., additional, Scordo, A., additional, Sgaramella, F., additional, Shi, H., additional, Silarski, M., additional, Sirghi, D., additional, Sirghi, F., additional, Skurzok, M., additional, Spallone, A., additional, Toho, K., additional, Vazquez Doce, O., additional, Widmann, E., additional, Yoshida, C., additional, Zmeskal, J., additional, and Curceanu, C., additional

Published
2023
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52. Testing CPT symmetry in ortho-positronium decays with positronium annihilation tomography

Author

Moskal, P., Gajos, A., Mohammed, M., Chhokar, J., Chug, N., Curceanu, C., Czerwiński, E., Dadgar, M., Dulski, K., Gorgol, M., Goworek, J., Hiesmayr, B. C., Jasińska, B., Kacprzak, K., Kapłon, Ł., Karimi, H., Kisielewska, D., Klimaszewski, K., Korcyl, G., Kowalski, P., Krawczyk, N., Krzemień, W., Kozik, T., Kubicz, E., Niedźwiecki, S., Parzych, S., Pawlik-Niedźwiecka, M., Raczyński, L., Raj, J., Sharma, S., Choudhary, S., Shopa, R. Y., Sienkiewicz, A., Silarski, M., Skurzok, M., Stępień, E. Ł., Tayefi, F., and Wiślicki, W.

Published
2021
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53. Kaonic atoms at the DAΦNE collider: a strangeness adventure

Author

Curceanu, C., primary, Abbene, L., additional, Amsler, C., additional, Bazzi, M., additional, Bettelli, M., additional, Borghi, G., additional, Bosnar, D., additional, Bragadireanu, M., additional, Buttacavoli, A., additional, Cargnelli, M., additional, Carminati, M., additional, Clozza, A., additional, Deda, G., additional, Del Grande, R., additional, De Paolis, L., additional, Dulski, K., additional, Fiorini, C., additional, Friščić, I., additional, Guaraldo, C., additional, Iliescu, M., additional, Iwasaki, M., additional, Khreptak, A., additional, Manti, S., additional, Marton, J., additional, Miliucci, M., additional, Moskal, P., additional, Napolitano, F., additional, Niedźwiecki, S., additional, Onishi, H., additional, Piscicchia, K., additional, Principato, F., additional, Sada, Y., additional, Scordo, A., additional, Sgaramella, F., additional, Shi, H., additional, Silarski, M., additional, Sirghi, D. L., additional, Sirghi, F., additional, Skurzok, M., additional, Spallone, A., additional, Toho, K., additional, Tüchler, M., additional, Doce, O. Vazquez, additional, Yoshida, C., additional, Zappettini, A., additional, and Zmeskal, J., additional

Published
2023
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54. TOF MLEM Adaptation for the Total-Body J-PET With a Realistic Analytical System Response Matrix

Author

Shopa, R. Y., primary, Baran, J., additional, Klimaszewski, K., additional, Krzemień, W., additional, Raczyński, L., additional, Wiślicki, W., additional, Brzeziński, K., additional, Chug, N., additional, Coussat, A., additional, Curceanu, C., additional, Czerwiński, E., additional, Dadgar, M., additional, Dulski, K., additional, Gajewski, J., additional, Gajos, A., additional, Hiesmayr, B. C., additional, Valsan, E. Kavya, additional, Korcyl, G., additional, Kozik, T., additional, Kumar, D., additional, Kapłon, Ł., additional, Moskal, G., additional, Niedźwiecki, S., additional, Panek, D., additional, Parzych, S., additional, Rio, E. Pérez del, additional, Ruciński, A., additional, Sharma, S., additional, Shivani, S., additional, Silarski, M., additional, Skurzok, M., additional, Stȩpień, E., additional, Ardebili, F. Tayefi, additional, Ardebili, K. Tayefi, additional, and Moskal, P., additional

Published
2023
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55. Measurement of gamma quantum interaction point in plastic scintillator with WLS strips

Author

Smyrski, J., Alfs, D., Bednarski, T., Białas, P., Czerwiński, E., Dulski, K., Gajos, A., Głowacz, B., Gupta-Sharma, N., Gorgol, M., Jasińska, B., Kajetanowicz, M., Kamińska, D., Korcyl, G., Kowalski, P., Krzemień, W., Krawczyk, N., Kubicz, E., Mohammed, M., Niedźwiecki, Sz., Pawlik-Niedźwiecka, M., Raczyński, L., Rudy, Z., Salabura, P., Silarski, M., Strzelecki, A., Wieczorek, A., Wiślicki, W., Wojnarska, J., Zgardzińska, B., Zieliński, M., and Moskal, P.

Published
2017
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56. Estimating relationship between the time over threshold and energy loss by photons in plastic scintillators used in the J-PET scanner

Author

Sharma, S., Chhokar, J., Curceanu, C., Czerwiński, E., Dadgar, M., Dulski, K., Gajewski, J., Gajos, A., Gorgol, M., Gupta-Sharma, N., Del Grande, R., Hiesmayr, B.C., Jasińska, B., Kacprzak, K., Kapłon, Ł., Karimi, H., Kisielewska, D., Klimaszewski, K., Korcyl, G., Kowalski, P., Kozik, T., Krawczyk, N., Krzemień, W., Kubicz, E., Mohammed, M., Niedzwiecki, Sz., Pałka, M., Pawlik-Niedźwiecka, M., Raczyński, L., Raj, J., Ruciński, A., Shivani, S., Shopa, R.Y., Silarski, M., Skurzok, M., Stępień, E.Ł., Wiślicki, W., Zgardzińska, B., and Moskal, P.

Published
2020
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57. Kaonic atoms measurements with SIDDHARTA-2

Author

Sgaramella, F., primary, Bazzi, M., additional, Bosnar, D., additional, Bragadireanu, M., additional, Cargnelli, M., additional, Carminati, M., additional, Clozza, A., additional, Deda, G., additional, Del Grande, R., additional, De Paolis, L., additional, Dulski, K., additional, Fabbietti, L., additional, Fiorini, C., additional, Friščić, I., additional, Guaraldo, C., additional, Iliescu, M., additional, Iwasaki, M., additional, Khreptak, A., additional, Manti, S., additional, Marton, J., additional, Miliucci, M., additional, Moskal, P., additional, Napolitano, F., additional, Niedźwiecki, S., additional, Ohnishi, H., additional, Piscicchia, K., additional, Sada, Y., additional, Scordo, A., additional, Shi, H., additional, Silarski, M., additional, Sirghi, D., additional, Sirghi, F., additional, Skurzok, M., additional, Spallone, A., additional, Toho, K., additional, Tüchler, M., additional, Yoshida, C., additional, Zmeskal, J., additional, and Curceanu, C., additional

Published
2023
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58. Investigating the E2 nuclear resonance effect in kaonic atoms

Author

De Paolis, L, primary, Bazzi, M, additional, Bosnar, D, additional, Bragadireanu, M, additional, Cargnelli, M, additional, Carminati, M, additional, Clozza, A, additional, Deda, G, additional, Del Grande, R, additional, Dulski, K, additional, Fiorini, C, additional, Friščić, I, additional, Guaraldo, C, additional, Iliescu, M, additional, Iwasaki, M, additional, King, P, additional, Khreptak, A, additional, Levi Sandri, P, additional, Manti, S, additional, Marton, J, additional, Miliucci, M, additional, Moskal, P, additional, Napolitano, F, additional, Niedźwiecki, S, additional, Ohnishi, H, additional, Piscicchia, K, additional, Sada, Y, additional, Scordo, A, additional, Sgaramella, F, additional, Shi, H, additional, Silarski, M, additional, Sirghi, D L, additional, Sirghi, F, additional, Skurzok, M, additional, Wycech, S, additional, Spallone, A, additional, Toho, K, additional, Tüchler, M, additional, Vazquez Doce, O, additional, Yoshida, C, additional, Zmeskal, J, additional, and Curceanu, C, additional

Published
2023
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60. The SIDDHARTA-2 experiment: preparation for the first kaonic deuterium measurement

Author

De Paolis, L., Bazzi, M., Bosnar, D., Bragadireanu, M., Cargnelli, M., Carminati, M., Clozza, A., Deda, G., Del Grande, R., Dulski, K., Fiorini, C., Friščić, I., Guaraldo, C., Iliescu, M., Iwasaki, M., King, P., Khreptak, A., Levi Sandri, P., Manti, S., Marton, J., Miliucci, M., Moskal, P., Napolitano, F., Niedźwiecki, S., Onishi, H., Piscicchia, K., Sada, Y., Scordo, A., Sgaramella, F., Shi, H., Silarski, M., Sirghi, D. L., Sirghi, F., Skurzok, M., Spallone, A., Toho, K., Tüchler, M., Yoshida, C., Zmeskal, J., and Curceanu, C.

Subjects
High energy physics, General
Abstract

The SIDDHARTA-2 experiment aims to perform the first measurement of the kaonic deuterium 2p → 1s x-ray transitions. The apparatus is presently installed at the interaction region of the DAΦNE electron-positron collider at the National Laboratories of Frascati (LNF-INFN), in Italy. Kaonic deuterium and kaonic hydrogen 2p → 1s x-ray transitions measurements, the latter one already performed by the SIDDHARTA collaboration, allow the determination of antikaon-nucleon scattering lengths. A description of the SIDDHARTA-2 apparatus in preparation for the kaonic deuterium measurement is provided in this paper.

Published
2022

61. From tests of discrete symmetries to medical imaging with J-PET detector

Author

Moskal, P., Baran, J., Chug, N., Curceanu, C., Czerwiński, E., Dadgar, M., Dulski, K., Gajewski, J., Gajos, A., Gorgol, M., Hiesmayr, B. C., Jasińska, B., Kacprzak, K., Kapłon, Ł., Karimi, H., Klimaszewski, K., Konieczka, P., Korcyl, G., Kozik, T., Krawczyk, N., Krzemień, W., Kubicz, E., Kumar, D., Niedźwiecki, S., Panek, D., Parzych, S., Elena Perez del Rio, Raczyński, L., Raj, J., Ruciński, A., Sharma, S., Shivani, Shopa, R. Y., Silarski, M., Skurzok, M., Stępień, E. Ł., Szczepanek, M., Tayefi, F., and Wiślicki, W.

Abstract

We present results on CPT symmetry tests in decays of positronium performed with the precision at the level of 10$^{-4}$, and positronium images determined with the prototype of the J-PET tomograph. The first full-scale prototype apparatus consists of 192 plastic scintillator strips readout from both ends with vacuum tube photomultipliers. Signals produced by photomultipliers are probed in the amplitude domain and are digitized by FPGA-based readout boards in triggerless mode. In this contribution we report on the first two- and three-photon positronium images and tests of CPT symmetry in positronium decays.

Published
2022

62. From tests of discrete symmetries to medical imaging with J-PET detector

Author

Moskal, Pawel, primary, Baran, J., additional, Chug, N., additional, Curceanu, C., additional, Czerwiński, E., additional, Dadgar, M., additional, Dulski, K., additional, Gajewski, J., additional, Gajos, A., additional, Gorgol, M., additional, Hiesmayr, B.C., additional, Jasinska, B., additional, Kacprzak, K., additional, Kapłon, Ł., additional, Karimi, H., additional, Klimaszewski, K., additional, Konieczka, P., additional, Korcyl, G., additional, Kozik, T., additional, Krawczyk, N., additional, Krzemień, W., additional, Kubicz, E., additional, Kumar, D., additional, Niedźwiecki, S., additional, Panek, D., additional, Parzych, S., additional, Perez, E., additional, Raczyński, L., additional, Raj, J., additional, Ruciński, A., additional, Sharma, S., additional, Shivani, Shivani, additional, Shopa, R.Y., additional, Silarski, M., additional, Skurzok, M., additional, Stępień, E.Ł., additional, Szczepanek, M., additional, Tayefi, F., additional, and Wiślicki, W., additional

Published
2022
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63. Performance assessment of the 2 γpositronium imaging with the total-body PET scanners

Author

Moskal, P., Kisielewska, D., Y. Shopa, R., Bura, Z., Chhokar, J., Curceanu, C., Czerwiński, E., Dadgar, M., Dulski, K., Gajewski, J., Gajos, A., Gorgol, M., Del Grande, R., C. Hiesmayr, B., Jasińska, B., Kacprzak, K., Kamińska, A., Kapłon, Ł, Karimi, H., Korcyl, G., Kowalski, P., Krawczyk, N., Krzemień, W., Kozik, T., Kubicz, E., Małczak, P., Mohammed, M., Niedźwiecki, Sz., Pałka, M., Pawlik-Niedźwiecka, M., Pędziwiatr, M., Raczyński, L., Raj, J., Ruciński, A., Sharma, S., Shivani, S., Silarski, M., Skurzok, M., Stępień, E. Ł., Vandenberghe, S., Wiślicki, W., and Zgardzińska, B.

Subjects
lcsh:Medical physics. Medical radiology. Nuclear medicine, PET, Total-body PET, lcsh:R895-920, Medical imaging, Positronium imaging, Original Research
Abstract

Purpose In living organisms, the positron-electron annihilation (occurring during the PET imaging) proceeds in about 30% via creation of a metastable ortho-positronium atom. In the tissue, due to the pick-off and conversion processes, over 98% of ortho-positronia annihilate into two 511 keV photons. In this article, we assess the feasibility for reconstruction of the mean ortho-positronium lifetime image based on annihilations into two photons. The main objectives of this work include the (i) estimation of the sensitivity of the total-body PET scanners for the ortho-positronium mean lifetime imaging using 2γ annihilations and (ii) estimation of the spatial and time resolution of the ortho-positronium image as a function of the coincidence resolving time (CRT) of the scanner. Methods Simulations are conducted assuming that radiopharmaceutical is labeled with 44 S c isotope emitting one positron and one prompt gamma. The image is reconstructed on the basis of triple coincidence events. The ortho-positronium lifetime spectrum is determined for each voxel of the image. Calculations were performed for cases of total-body detectors build of (i) LYSO scintillators as used in the EXPLORER PET and (ii) plastic scintillators as anticipated for the cost-effective total-body J-PET scanner. To assess the spatial and time resolution, the four cases were considered assuming that CRT is equal to 500 ps, 140 ps, 50 ps, and 10 ps. Results The estimated total-body PET sensitivity for the registration and selection of image forming triple coincidences (2γ+γ prompt) is larger by a factor of 13.5 (for LYSO PET) and by factor of 5.2 (for plastic PET) with respect to the sensitivity for the standard 2γ imaging by LYSO PET scanners with AFOV = 20 cm. The spatial resolution of the ortho-positronium image is comparable with the resolution achievable when using TOF-FBP algorithms already for CRT = 50 ps. For the 20-min scan, the resolution better than 20 ps is expected for the mean ortho-positronium lifetime image determination. Conclusions Ortho-positronium mean lifetime imaging based on the annihilations into two photons and prompt gamma is shown to be feasible with the advent of the high sensitivity total-body PET systems and time resolution of the order of tens of picoseconds.

Published
2020

65. Simulating NEMA characteristics of the modular total-body J-PET scanner—an economic total-body PET from plastic scintillators

Author

Moskal, P, primary, Kowalski, P, additional, Shopa, R Y, additional, Raczyński, L, additional, Baran, J, additional, Chug, N, additional, Curceanu, C, additional, Czerwiński, E, additional, Dadgar, M, additional, Dulski, K, additional, Gajos, A, additional, Hiesmayr, B C, additional, Kacprzak, K, additional, Kapłon, Ł, additional, Kisielewska, D, additional, Klimaszewski, K, additional, Kopka, P, additional, Korcyl, G, additional, Krawczyk, N, additional, Krzemień, W, additional, Kubicz, E, additional, Niedźwiecki, Sz, additional, Parzych, Sz, additional, Raj, J, additional, Sharma, S, additional, Shivani, S, additional, Stępień, E, additional, Tayefi, F, additional, and Wiślicki, W, additional

Published
2021
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66. Investigation of Novel Preclinical Total Body PET Designed With J-PET Technology: A Simulation Study

Author

Dadgar, M., Parzych, S., Tayefi Ardebili, F., Baran, J., Chug, N., Curceanu, C., Czerwinski, E., Dulski, K., Eliyan, K., Gajos, A., Hiesmayr, B. C., Kacprzak, K., Kaplon, L., Klimaszewski, K., Konieczka, P., Korcyl, G., Kozik, T., Krzemien, W., Kumar, D., Niedzwiecki, S., Panek, D., Perez del Rio, E., Raczynski, L., Sharma, S., Shivani, Shopa, R.Y., Skurzok, M., Tayefi Ardebili, K., Vandenberghe, S., Wislicki, W., Stepien, E. L., and Moskal, P.

Abstract

The growing interest in human-grade total body positron emission tomography (PET) systems has also application in small animal research. Due to the existing limitations in human-based studies involving drug development and novel treatment monitoring, animal-based research became a necessary step for testing and protocol preparation. In this simulation-based study two unconventional, cost-effective small animal total body PET scanners (for mouse and rat studies) have been investigated in order to inspect their feasibility for preclinical research. They were designed with the novel technology explored by the Jagiellonian-PET (J-PET) Collaboration. Two main PET characteristics: sensitivity and spatial resolution were mainly inspected to evaluate their performance. Moreover, the impact of the scintillator dimension and time-of-flight on the latter parameter was examined in order to design the most efficient tomographs. The presented results show that for mouse TB J-PET the achievable system sensitivity is equal to 2.35% and volumetric spatial resolution to 9.46 ± 0.54 mm3, while for rat TB J-PET they are equal to 2.6% and 14.11 ± 0.80 mm3, respectively. Furthermore, it was shown that the designed tomographs are almost parallax-free systems, hence, they resolve the problem of the acceptance criterion tradeoff between enhancing spatial resolution and reducing sensitivity.

Published
2023
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67. Studies of discrete symmetries in a purely leptonic system using the Jagiellonian Positron Emission Tomograph

Author

Moskal P., Alfs D., Bednarski T., Białas P., Curceanu C., Czerwiński E., Dulski K., Gajos A., Głowacz B., Gupta-Sharma N., Gorgol M., Hiesmayr B. C., Jasińska B., Kamińska D., Khreptak O., Korcyl G., Kowalski P., Krzemień W., Krawczyk N., Kubicz E., Mohammed M., Niedźwiecki Sz., Pawlik-Niedńwiecka M., Raczyński L., Rudy Z., Silarski M., Smyrski J., Wieczorek A., Wiślicki W., Zgardzińska B., and Zieliński M.

Subjects
Physics, QC1-999
Abstract

Discrete symmetries such as parity (P), charge-conjugation (C) and time reversal (T) are of fundamental importance in physics and cosmology. Breaking of charge conjugation symmetry (C) and its combination with parity (CP) constitute necessary conditions for the existence of the asymmetry between matter and antimatter in the observed Universe. The presently known sources of discrete symmetries violations can account for only a tiny fraction of the excess of matter over antimatter. So far CP and T symmetries violations were observed only for systems involving quarks and they were never reported for the purely leptonic objects. In this article we describe briefly an experimental proposal for the test of discrete symmetries in the decays of positronium atom which is made exclusively of leptons. The experiments are conducted by means of the Jagiellonian Positron Emission Tomograph (J-PET) which is constructed from strips of plastic scintillators enabling registration of photons from the positronium annihilation. J-PET tomograph together with the positronium target system enable to measure expectation values for the discrete symmetries odd operators constructed from (i) spin vector of the ortho-positronium atom, (ii) momentum vectors of photons originating from the decay of positronium, and (iii) linear polarization direction of annihilation photons. Linearly polarized positronium will be produced in the highly porous aerogel or polymer targets, exploiting longitudinally polarized positrons emitted by the sodium 22Na isotope. Information about the polarization vector of orthopositronium will be available on the event by event basis and will be reconstructed from the known position of the positron source and the reconstructed position of the orthopositronium annihilation. In 2016 the first tests and calibration runs are planned, and the data collection with high statistics will commence in the year 2017.

Published
2016
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68. J-PET detector system for studies of the electron-positron annihilations

Author

Pawlik-Niedźwiecka M., Khreptak O., Gajos A., Wieczorek A., Alfs D., Bednarski T., Białas P., Curceanu C., Czerwiński E., Dulski K., Głowacz B., Gupta-Sharma N., Gorgol M., Hiesmayr B. C., Jasińska B., Kamińska D., Korcyl G., Kowalski P., Krzmień W., Krawczyk N., Kubicz E., Mohammed M., Niedźwiecki Sz., Raczyński L., Rudy Z., Silarski M., Wiślicki W., Zgardzińska B., Zieliński M., and Moskal P.

Subjects
Physics, QC1-999
Abstract

Jagiellonian Positron Emission Tomograph (J-PET) has been recently constructed at the Jagiellonian University as a prototype of a cost-effective scanner for the metabolic imaging of the whole human body. J-PET detector is optimized for the measurement of momentum and polarization of photons from the electron-positron annihilations. It is built out of strips of plastic scintillators, forming three cylindrical layers. As detector of gamma quanta it will be used for studies of discrete symmetries and multiparticle entanglement of photons originating from the decays of ortho-positronium atoms.

Published
2016
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69. Performance assessment of the 2 \gamma positronium imaging with the total-body PET scanners

Author

Moskal, P., Kisielewska, D., Shopa, R. Y., Bura, Z., Chhokar, J., Curceanu, C., Czerwinski, E., Dadgar, Meysam, Dulski, K., Gajewski, J., Gajos, A., Gorgol, M., Del Grande, R., Hiesmayr, B. C., Jasinska, B., Kacprzak, K., Kaminska, A., Kaplon, L., Karimi, H., Korcyl, G., Kowalski, P., Krawczyk, N., Krzemien, W., Kozik, T., Kubicz, E., Malczak, P., Mohammed, M., Niedzwiecki, Sz, Palka, M., Pawlik-Niedzwiecka, M., Pedziwiatr, M., Raczynski, L., Raj, J., Rucinski, A., Sharma, S., Shivani, S., Silarski, M., Skurzok, M., Stepien, E. L., Vandenberghe, Stefaan, Wislicki, W., and Zgardzinska, B.

Subjects
POSITRON-ANNIHILATION SPECTROSCOPY, Technology and Engineering, PET, RESOLUTION, TOMOGRAPHY, Total-body PET, OF-FLIGHT RECONSTRUCTION, Medical imaging, FREE-VOLUME, Positronium imaging, TIME
Abstract

Purpose In living organisms, the positron-electron annihilation (occurring during the PET imaging) proceeds in about 30% via creation of a metastable ortho-positronium atom. In the tissue, due to the pick-off and conversion processes, over 98% of ortho-positronia annihilate into two 511 keV photons. In this article, we assess the feasibility for reconstruction of the mean ortho-positronium lifetime image based on annihilations into two photons. The main objectives of this work include the (i) estimation of the sensitivity of the total-body PET scanners for the ortho-positronium mean lifetime imaging using 2 gamma annihilations and (ii) estimation of the spatial and time resolution of the ortho-positronium image as a function of the coincidence resolving time (CRT) of the scanner. Methods Simulations are conducted assuming that radiopharmaceutical is labeled with(44)Scisotope emitting one positron and one prompt gamma. The image is reconstructed on the basis of triple coincidence events. The ortho-positronium lifetime spectrum is determined for each voxel of the image. Calculations were performed for cases of total-body detectors build of (i) LYSO scintillators as used in the EXPLORER PET and (ii) plastic scintillators as anticipated for the cost-effective total-body J-PET scanner. To assess the spatial and time resolution, the four cases were considered assuming that CRT is equal to 500 ps, 140 ps, 50 ps, and 10 ps. Results The estimated total-body PET sensitivity for the registration and selection of image forming triple coincidences (2 gamma+gamma(prompt)) is larger by a factor of 13.5 (for LYSO PET) and by factor of 5.2 (for plastic PET) with respect to the sensitivity for the standard 2 gamma imaging by LYSO PET scanners with AFOV = 20 cm. The spatial resolution of the ortho-positronium image is comparable with the resolution achievable when using TOF-FBP algorithms already for CRT = 50 ps. For the 20-min scan, the resolution better than 20 ps is expected for the mean ortho-positronium lifetime image determination. Conclusions Ortho-positronium mean lifetime imaging based on the annihilations into two photons and prompt gamma is shown to be feasible with the advent of the high sensitivity total-body PET systems and time resolution of the order of tens of picoseconds.

Published
2020

70. Hit-Time and Hit-Position Reconstruction in Strips of Plastic Scintillators Using Multithreshold Readouts

Author

Sharma, N.G., primary, Silarski, M., additional, Chhokar, J., additional, Czerwinski, E., additional, Curceanu, C., additional, Dulski, K., additional, Farbaniec, K., additional, Gajos, A., additional, Del Grande, R., additional, Gorgol, M., additional, Hiesmayr, B. C., additional, Jasinska, B., additional, Kacprzak, K., additional, Kaplon, L., additional, Kisielewska, D., additional, Klimaszewski, K., additional, Korcyl, G., additional, Kowalski, P., additional, Krawczyk, N., additional, Krzemien, W., additional, Kozik, T., additional, Kubicz, E., additional, Mohammed, M., additional, Niedzwiecki, Sz., additional, Palka, M., additional, Pawlik-Niedzwiecka, M., additional, Raczynski, L., additional, Raj, J., additional, Sharma, S., additional, Shivani, S., additional, Shopa, R. Y., additional, Skurzok, M., additional, Wislicki, W., additional, Zgardzinska, B., additional, and Moskal, P., additional

Published
2020
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75. Synchronization and Calibration of the 24-Modules J-PET Prototype With 300-mm Axial Field of View.

Author

Moskal, P., Bednarski, T., Niedzwiecki, Sz., Silarski, M., Czerwinski, E., Kozik, T., Chhokar, J., Bala, M., Curceanu, C., Grande, R. Del, Dadgar, M., Dulski, K., Gajos, A., Gorgol, M., Gupta-Sharma, N., Hiesmayr, B. C., Jasinska, B., Kacprzak, K., Kaplon, L., and Karimi, H.

Subjects
POSITRON emission tomography, DATA acquisition systems, COINCIDENCE, CALIBRATION, PROTOTYPES, ATTENUATION of light
Abstract

Research conducted in the framework of the Jagiellonian-PET (J-PET) project aims to develop a cost-effective total-body positron emission tomography scanner. As a first step on the way to construct a full-scale J-PET tomograph from long strips of plastic scintillators, a 24-strip prototype was built and tested. The prototype consists of detection modules arranged axially forming a cylindrical diagnostic chamber with the inner diameter of 360 mm and the axial field-of-view of 300 mm. Promising perspectives for a low-cost construction of a total-body PET scanner are opened due to an axial arrangement of strips of plastic scintillators, which have a small light attenuation, superior timing properties, and the possibility of cost-effective increase of the axial field-of-view. The presented prototype comprises dedicated solely digital front-end electronic circuits and a triggerless data acquisition system which required the development of new calibration methods including time, thresholds, and gain synchronization. The system and elaborated calibration methods, including first results of the 24-module J-PET prototype, are presented and discussed. The achieved coincidence resolving time equals to ${\mathrm {CRT}}=490\pm 9$ ps. This value can be translated to the position reconstruction accuracy $\sigma (\Delta l) =18$ mm, which is fairly position independent. [ABSTRACT FROM AUTHOR]

Published
2021
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76. Evaluation of Single-Chip, Real-Time Tomographic Data Processing on FPGA SoC Devices

Author

Korcyl, G., primary, Hiesmayr, B. C., additional, Jasinska, B., additional, Kacprzak, K., additional, Kajetanowicz, M., additional, Kisielewska, D., additional, Kowalski, P., additional, Kozik, T., additional, Krawczyk, N., additional, Krzemien, W., additional, Kubicz, E., additional, Bialas, P., additional, Mohammed, M., additional, Niedzwiecki, Sz., additional, Pawlik-Niedzwiecka, M., additional, Palka, M., additional, Raczynski, L., additional, Rajda, P., additional, Rudy, Z., additional, Salabura, P., additional, Sharma, N. G., additional, Sharma, S., additional, Curceanu, C., additional, Shopa, R. Y., additional, Skurzok, M., additional, Silarski, M., additional, Strzempek, P., additional, Wieczorek, A., additional, Wislicki, W., additional, Zaleski, R., additional, Zgardzinska, B., additional, Zielinski, M., additional, Moskal, P., additional, Czerwinski, E., additional, Dulski, K., additional, Flak, B., additional, Gajos, A., additional, Glowacz, B., additional, and Gorgol, M., additional

Published
2018
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77. A METHOD FOR TIME CALIBRATION OF PET SYSTEMS USING FIXED β+ RADIOACTIVE SOURCE.

Author

DULSKI, K., SILARSKI, M., and MOSKAL, P.

Subjects
*CALIBRATION, *EMISSION tomography equipment, *POSITRON emission tomography
Abstract

A method for the time calibration of the Time-of-Flight Positron Emmission Tomograph (TOF-PET) systems using fixed sources is described. Compared to the commercially used calibration methods, the new method gives a chance to run the calibration during the medical scan. Reduction of the time needed for calibration can increase the number of patients examined by PET. The process of calibration of the Jagiellonian Positron Emission Tomograph (J-PET) detector is shown as an example. [ABSTRACT FROM AUTHOR]

Published
2020
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78. Estimating the NEMA characteristics of the J-PET tomograph using the GATE package

Author

Kowalski, P, primary, Wiślicki, W, additional, Shopa, R Y, additional, Raczyński, L, additional, Klimaszewski, K, additional, Curcenau, C, additional, Czerwiński, E, additional, Dulski, K, additional, Gajos, A, additional, Gorgol, M, additional, Gupta-Sharma, N, additional, Hiesmayr, B, additional, Jasińska, B, additional, Kapłon, Ł, additional, Kisielewska-Kamińska, D, additional, Korcyl, G, additional, Kozik, T, additional, Krzemień, W, additional, Kubicz, E, additional, Mohammed, M, additional, Niedźwiecki, S, additional, Pałka, M, additional, Pawlik-Niedźwiecka, M, additional, Raj, J, additional, Rakoczy, K, additional, Rudy, Z, additional, Sharma, S, additional, Shivani, S, additional, Silarski, M, additional, Skurzok, M, additional, Zgardzińska, B, additional, Zieliński, M, additional, and Moskal, P, additional

Published
2018
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79. Human Tissue Investigations Using PALS Technique - Free Radicals Influence

Author

Jasińska, B., primary, Zgardzińska, B., additional, Chołubek, G., additional, Pietrow, M., additional, Gorgol, M., additional, Wiktor, K., additional, Wysogląd, K., additional, Białas, P., additional, Curceanu, C., additional, Czerwiński, E., additional, Dulski, K., additional, Gajos, A., additional, Głowacz, B., additional, Hiesmayr, B.C., additional, Jodłowska-Jędrych, B., additional, Kamińska, D., additional, Korcyl, G., additional, Kowalski, P., additional, Kozik, T., additional, Krawczyk, N., additional, Krzemień, W., additional, Kubicz, E., additional, Mohammed, Muhsin, additional, Pawlik-Niedźwiecka, M., additional, Niedźwiecki, S., additional, Pałka, M., additional, Raczyński, L., additional, Rudy, Z., additional, Sharma, N.G., additional, Sharma, S., additional, Shopa, R., additional, Silarski, M., additional, Skurzok, M., additional, Wieczorek, A., additional, Wiktor, H., additional, Wiślicki, W., additional, Zieliński, M., additional, and Moskal, P., additional

Published
2017
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80. Analysis Procedure of the Positronium Lifetime Spectra for the J-PET Detector

Author

Dulski, K., primary, Zgardzińska, B., additional, Białas, P., additional, Curceanu, C., additional, Czerwiński, E., additional, Gajos, A., additional, Głowacz, B., additional, Gorgol, M., additional, Hiesmayr, B.C., additional, Jasińska, B., additional, Kisielewska-Kamińska, D., additional, Korcyl, G., additional, Kowalski, P., additional, Kozik, T., additional, Krawczyk, N., additional, Krzemień, W., additional, Kubicz, E., additional, Mohammed, Muhsin, additional, Pawlik-Niedźwiecka, M., additional, Niedźwiecki, S., additional, Pałka, M., additional, Raczyński, L., additional, Raj, J., additional, Rudy, Z., additional, Sharma, N.G., additional, Sharma, S., additional, Shivani, Shivani, additional, Shopa, R.Y., additional, Silarski, M., additional, Skurzok, M., additional, Wieczorek, A., additional, Wiślicki, W., additional, Zieliński, M., additional, and Moskal, P., additional

Published
2017
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81. Determination of the 3��fraction from positron annihilation in mesoporous materials for symmetry violation experiment with J-PET scanner

Author

Jasi��ska, B., Gorgol, M., Wiertel, M., Zaleski, R., Alfs, D., Bednarski, T., Bia��as, P., Czerwi��ski, E., Dulski, K., Gajos, A., G��owacz, B., Kami��ska, D., Kap��on, ��., Korcyl, G., Kowalski, P., Kozik, T., Krzemie��, W., Kubicz, E., Mohammed, M., Nied��wiecki, Sz., Pa��ka, M., Raczy��ski, L., Rudy, Z., Rundel, O., Sharma, N. G., Silarski, M., S��omski, A., Strzelecki, A., Wieczorek, A., Wi��licki, W., Zgardzi��ska, B., Zieli��ski, M., and Moskal, P.

Subjects
FOS: Physical sciences, Instrumentation and Detectors (physics.ins-det), Nuclear Experiment (nucl-ex)
Abstract

Various mesoporous materials were investigated to choose the best material for experiments requiring high yield of long-lived positronium. We found that the fraction of 3��annihilation determined using ��-ray energy spectra and positron annihilation lifetime spectra (PAL) changed from 20% to 25%. The 3gamma fraction and o-Ps formation probability in the polymer XAD-4 is found to be the largest. Elemental analysis performed using scanning electron microscop (SEM) equipped with energy-dispersive X-ray spectroscop EDS show high purity of the investigated materials., 12 pages, 2 figures

Published
2016
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82. Multichannel FPGA based MVT system for high precision time (20 ps RMS) and charge measurement

Author

Pałka, M., primary, Strzempek, P., additional, Korcyl, G., additional, Bednarski, T., additional, Niedźwiecki, Sz., additional, Białas, P., additional, Czerwiński, E., additional, Dulski, K., additional, Gajos, A., additional, Głowacz, B., additional, Gorgol, M., additional, Jasińska, B., additional, Kamińska, D., additional, Kajetanowicz, M., additional, Kowalski, P., additional, Kozik, T., additional, Krzemień, W., additional, Kubicz, E., additional, Mohhamed, M., additional, Raczyński, L., additional, Rudy, Z., additional, Rundel, O., additional, Salabura, P., additional, Sharma, N.G., additional, Silarski, M., additional, Smyrski, J., additional, Strzelecki, A., additional, Wieczorek, A., additional, Wiślicki, W., additional, Zieliński, M., additional, Zgardzińska, B., additional, and Moskal, P., additional

Published
2017
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83. Calculation of the time resolution of the J-PET tomograph using kernel density estimation

Author

Raczyński, L, primary, Wiślicki, W, additional, Krzemień, W, additional, Kowalski, P, additional, Alfs, D, additional, Bednarski, T, additional, Białas, P, additional, Curceanu, C, additional, Czerwiński, E, additional, Dulski, K, additional, Gajos, A, additional, Głowacz, B, additional, Gorgol, M, additional, Hiesmayr, B, additional, Jasińska, B, additional, Kamińska, D, additional, Korcyl, G, additional, Kozik, T, additional, Krawczyk, N, additional, Kubicz, E, additional, Mohammed, M, additional, Pawlik-Niedźwiecka, M, additional, Niedźwiecki, S, additional, Pałka, M, additional, Rudy, Z, additional, Rundel, O, additional, Sharma, N G, additional, Silarski, M, additional, Smyrski, J, additional, Strzelecki, A, additional, Wieczorek, A, additional, Zgardzińska, B, additional, Zieliński, M, additional, and Moskal, P, additional

Published
2017
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84. J-PET: A New Technology for the Whole-body PET Imaging

Author

Niedźwiecki, S., primary, Białas, P., additional, Curceanu, C., additional, Czerwiński, E., additional, Dulski, K., additional, Gajos, A., additional, Głowacz, B., additional, Gorgol, M., additional, Hiesmayr, B.C., additional, Jasińska, B., additional, Kapłon, Ł., additional, Kisielewska-Kamińska, D., additional, Korcyl, G., additional, Kowalski, P., additional, Kozik, T., additional, Krawczyk, N., additional, Krzemień, W., additional, Kubicz, E., additional, Mohammed, M., additional, Pawlik-Niedźwiecka, M., additional, Pałka, M., additional, Raczyński, L., additional, Rudy, Z., additional, Sharma, N.G., additional, Sharma, S., additional, Shopa, R.Y., additional, Silarski, M., additional, Skurzok, M., additional, Wieczorek, A., additional, Wiślicki, W., additional, Zgardzińska, B., additional, Zieliński, M., additional, and Moskal, P., additional

Published
2017
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85. Introduction of Total Variation Regularization into Filtered Backprojection Algorithm

Author

Raczyński, L., primary, Wiślicki, W., additional, Klimaszewski, K., additional, Krzemień, W., additional, Kowalski, P., additional, Shopa, R.Y., additional, Białas, P., additional, Curceanu, C., additional, Czerwiński, E., additional, Dulski, K., additional, Gajos, A., additional, Głowacz, B., additional, Gorgol, M., additional, Hiesmayr, B., additional, Jasińska, B., additional, Kisielewska-Kamińska, D., additional, Korcyl, G., additional, Kozik, T., additional, Krawczyk, N., additional, Kubicz, E., additional, Mohammed, M., additional, Pawlik-Niedźwiecka, M., additional, Niedźwiecki, S., additional, Pałka, M., additional, Rudy, Z., additional, Sharma, N.G., additional, Sharma, S., additional, Silarski, M., additional, Skurzok, M., additional, Wieczorek, A., additional, Zgardzińska, B., additional, Zieliński, M., additional, and Moskal, P., additional

Published
2017
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86. Commissioning of the J-PET Detector for Studies of Decays of Positronium Atoms

Author

Czerwiński, E., primary, Dulski, K., additional, Białas, P., additional, Curceanu, C., additional, Gajos, A., additional, Głowacz, B., additional, Gorgol, M., additional, Hiesmayr, B.C., additional, Jasińska, B., additional, Kisielewska, D., additional, Korcyl, G., additional, Kowalski, P., additional, Kozik, T., additional, Krawczyk, N., additional, Krzemień, W., additional, Kubicz, E., additional, Mohammed, M., additional, Niedźwiecki, Sz., additional, Pałka, M., additional, Pawlik-Niedźwiecka, M., additional, Raczyński, L., additional, Rudy, Z., additional, Sharma, N.G., additional, Sharma, S., additional, Shopa, R.Y., additional, Silarski, M., additional, Skurzok, M., additional, Wieczorek, A., additional, Wiślicki, W., additional, Zgardzińska, B., additional, Zieliński, M., additional, and Moskal, P., additional

Published
2017
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87. Three-dimensional Image Reconstruction in J-PET Using Filtered Back-projection Method

Author

Shopa, R.Y., primary, Klimaszewski, K., additional, Kowalski, P., additional, Krzemień, W., additional, Raczyński, L., additional, Wiślicki, W., additional, Białas, P., additional, Curceanu, C., additional, Czerwiński, E., additional, Dulski, K., additional, Gajos, A., additional, Głowacz, B., additional, Gorgol, M., additional, Hiesmayr, B., additional, Jasińska, B., additional, Kisielewska-Kamińska, D., additional, Korcyl, G., additional, Kozik, T., additional, Krawczyk, N., additional, Kubicz, E., additional, Mohammed, M., additional, Pawlik-Niedźwiecka, M., additional, Niedźwiecki, S., additional, Pałka, M., additional, Rudy, Z., additional, Sharma, N.G., additional, Sharma, S., additional, Silarski, M., additional, Skurzok, M., additional, Wieczorek, A., additional, Zgardzińska, B., additional, Zieliński, M., additional, and Moskal, P., additional

Published
2017
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88. A feasibility study of ortho-positronium decays measurement with the J-PET scanner based on plastic scintillators

Author

Kamińska, D., primary, Gajos, A., additional, Czerwiński, E., additional, Alfs, D., additional, Bednarski, T., additional, Białas, P., additional, Curceanu, C., additional, Dulski, K., additional, Głowacz, B., additional, Gupta-Sharma, N., additional, Gorgol, M., additional, Hiesmayr, B. C., additional, Jasińska, B., additional, Korcyl, G., additional, Kowalski, P., additional, Krzemień, W., additional, Krawczyk, N., additional, Kubicz, E., additional, Mohammed, M., additional, Niedźwiecki, Sz., additional, Pawlik-Niedźwiecka, M., additional, Raczyński, L., additional, Rudy, Z., additional, Silarski, M., additional, Wieczorek, A., additional, Wiślicki, W., additional, Zgardzińska, B., additional, Zieliński, M., additional, and Moskal, P., additional

Published
2016
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89. Sampling FEE and Trigger-less DAQ for the J-PET Scanner

Author

Korcyl, G., primary, Alfs, D., additional, Bednarski, T., additional, Białas, P., additional, Czerwiński, E., additional, Dulski, K., additional, Gajos, A., additional, Głowacz, B., additional, Jasińska, B., additional, Kamińska, D., additional, Kapłon, Ł., additional, Kowalski, P., additional, Kozik, T., additional, Krzemień, W., additional, Kubicz, E., additional, Mohammed, M., additional, Niedźwiecki, Sz., additional, Pałka, M., additional, Pawlik-Niedźwiecka, M., additional, Raczyński, L., additional, Rudy, Z., additional, Rundel, O., additional, Sharma, N.G., additional, Silarski, M., additional, Słomski, A., additional, Stoła, K., additional, Strzelecki, A., additional, Wieczorek, A., additional, Wiślicki, W., additional, Zgardzińska, B.K., additional, Zieliński, M., additional, and Moskal, P., additional

Published
2016
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90. Determination of the $3\gamma $ Fraction from Positron Annihilation in Mesoporous Materials for Symmetry Violation Experiment with J-PET Scanner

Author

Jasińska, B., primary, Gorgol, M., additional, Wiertel, M., additional, Zaleski, R., additional, Alfs, D., additional, Bednarski, T., additional, Białas, P., additional, Czerwiński, E., additional, Dulski, K., additional, Gajos, A., additional, Głowacz, B., additional, Kamińska, D., additional, Kapłon, Ł., additional, Korcyl, G., additional, Kowalski, P., additional, Kozik, T., additional, Krzemień, W., additional, Kubicz, E., additional, Mohammed, M., additional, Niedźwiecki, Sz., additional, Pałka, M., additional, Raczyński, L., additional, Rudy, Z., additional, Rundel, O., additional, Sharma, N.G., additional, Silarski, M., additional, Słomski, A., additional, Strzelecki, A., additional, Wieczorek, A., additional, Wiślicki, W., additional, Zgardzińska, B., additional, Zieliński, M., additional, and Moskal, P., additional

Published
2016
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91. A novel TOF-PET detector based on plastic scintillators

Author

Krzemien, W., primary, Alfs, D., additional, Bednarski, T., additional, Bialas, P., additional, Czerwinski, E., additional, Dulski, K., additional, Gajos, A., additional, Glowacz, B., additional, Gorgol, M., additional, Jasinska, B., additional, Kaminska, D., additional, Kaplon, L., additional, Korcyl, G., additional, Kowalski, P., additional, Kozik, T., additional, Kubicz, E., additional, Mohammed, M., additional, Niedzwiecki, Sz., additional, Palka, M., additional, Pawlik-Niedzwiecka, M., additional, Raczynski, L., additional, Rudy, Z., additional, Rundel, O., additional, Sharma, N. G., additional, Silarski, M., additional, Slomski, A., additional, Stola, K., additional, Strzelecki, A., additional, Wieczorek, A., additional, Wislicki, W., additional, Zgradzinska, B. K., additional, Zielinski, M., additional, and Moskal, P., additional

Published
2015
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92. Preliminary Studies of J-PET Detector Spatial Resolution.

Author

PAWLIK-NIEDŹWIECKA, M., NIEDŹWIECKI, S., ALFS, D., BIAŁAS, P., CURCEANU, C., CZERWIŃSKI, E., DULSKI, K., GAJOS, A., GŁOWACZ, B., GORGOL, M., HIESMAYR, B. C., JASIŃSKA, B., KISIELEWSKA, D., KORCYL, G., KOWALSKI, P., KOZIK, T., KRAWCZYK, N., KRZEMIEŃ, W., KUBICZ, E., and MOHAMMED, M.

Subjects
SCINTILLATORS, POSITRON annihilation, SPECTRUM analysis, DIAGNOSTIC imaging, QUANTUM optics, MAGNETIC field measurements
Abstract

The J-PET detector, based on long plastic scintillator strips, was recently constructed at the Jagiellonian University. It consists of 192 modules axially arranged into three layers, read out from both sides by digital constant-threshold front-end electronics. This work presents preliminary results of measurements of the spatial resolution of the J-PET tomograph performed with 22Na source placed at selected position inside the detector chamber. [ABSTRACT FROM AUTHOR]

Published
2017
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93. A Method to Produce Linearly Polarized Positrons and Positronium Atoms with the J-PET Detector.

Author

MOHAMMED, MUHSIN, BIAŁAS, P., CURCEANU, C., CZERWIŃSKI, E., DULSKI, K., GAJOS, A., GŁOWACZ, B., GORGOL, M., HIESMAYR, B. C., JASIŃSKA, B., KISIELEWSKA, D., KORCYL, G., KOWALSKI, P., KOZIK, T., KRAWCZYK, N., KRZEMIEŃ, W., KUBICZ, E., PAWLIK-NIEDŹWIECKA, M., NIEDŹWIECKI, S., and PAŁKA, M.

Subjects
POSITRON annihilation, DENSITY functional theory, MAGNETIC fields, MOLECULAR dynamics, QUANTUM optics
Abstract

A method for creating linearly polarized positrons and ortho-positronium (o-Ps) atoms with the J-PET detector is presented. The unique geometry and properties of the J-PET tomography enable one to design a positron source such that the quantization axis for the estimation of the linear polarization of produced o-Ps can be determined on the event by event basis in a direction of the positron motion. We intend to use 22Na or other β+ decay isotopes as a source of polarized positrons. Due to the parity violation in the beta decay, the emitted positrons are longitudinally polarized. The choice of the quantization axis is based on the known position of the positron emitter and the reconstructed position of the positronium annihilation. We show that the J-PET tomography is equipped with all needed components. [ABSTRACT FROM AUTHOR]

Published
2017
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95. Loss of intercellular junctional communication correlates with metastatic potential in mammary adenocarcinoma cells.

Author

Nicolson, G L, Dulski, K M, and Trosko, J E

Abstract

A series of rat 13762NF mammary adenocarcinoma cell sublines and clones of various spontaneous pulmonary metastatic potentials from the mammary fat pads of syngeneic rats were examined for their intercellular junctional communication. Using the scrape-loading dye-transfer technique to introduce Lucifer yellow (Mr 457) into cells, we measured the abilities of 13762NF cells to transfer dye to adjacent cells. There was an excellent correlation between loss of Lucifer yellow dye transfer and spontaneous metastatic potential (average total volume of lung metastases inversely correlated to % cells coupled, r = 0.93; average total number of lung metastases inversely correlated to % cells coupled, r = 0.91). The data suggest that high metastatic potentials are closely correlated with loss of intercellular junctional communication in these malignant mammary tumor cells.

Published
1988
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96. Towards 2+1 photon tomography: Energy-based selection of two 511 keV photons and a prompt photon with the J-PET scanner

Author

Masełek, R., Krzemien, W., Konrad Klimaszewski, Raczyński, L., Kowalski, P., Shopa, R., Wiślicki, W., Białas, P., Curceanu, C., Czerwiński, E., Dulski, K., Gajos, A., Głowacz, B., Gorgol, M., Hiesmayr, B., Jasińska, B., Kisielewska, D., Korcyl, G., Kozik, T., Krawczyk, N., Kubicz, E., Mohammed, M., Pawlik-Niedźwiecka, M., Niedźwiecki, S., Pałka, M., Rudy, Z., Sharma, N. G., Sharma, S., Silarski, M., Skurzok, M., Wieczorek, A., Zgardzińska, B., Zieliński, M., and Moskal, P.

Subjects
Physics - Instrumentation and Detectors, Astrophysics::High Energy Astrophysical Phenomena, FOS: Physical sciences, Medical Physics (physics.med-ph), Instrumentation and Detectors (physics.ins-det), Physics - Medical Physics
Abstract

The possibility to separate signals caused by 511 keV photons created in annihilation of electron-positron pairs and the so-called prompt photons from nuclei de- excitation is investigated. It could potentially be used to improve the quality of reconstructed images in the J-PET scanner in 2+1 photon tomography. Firstly, a research is conducted for several radioisotopes that decay via \b{eta}+ decay followed by de-excitation of an excited nucleus. Efficiency, purity and false positive rate are calculated for each isotope as a function of energy deposited threshold, with a hypothesis that signals caused by 511 keV photons deposit smaller values of energy than 1 z 13the selected threshold, while prompt photons deposit larger energy than the threshold. Analysis of the results accompanied with physical properties of radioisotopes suggests using 44 Sc, which is the most promising candidate for medical applications. With the use of GATE and J-POS simulation software, in-phantom scattering was introduced and the best energy deposited threshold value was estimated to be approximately 375 keV. It corresponds to almost 100% efficiency for 511 keV signals, 75% purity for 511 keV photons, and approximately 70% efficiency and purity for prompt photons., Comment: 13 pages, 11 figures, 2 tables, proceedings from "Young Scientists" conferences in Warsaw, Poland, 2017

98. SPLIT: Statistical Positronium Lifetime Image Reconstruction via Time-Thresholding.

Author

Huang B, Li T, Arino-Estrada G, Dulski K, Shopa RY, Moskal P, Stepien E, and Qi J

Subjects
Humans, Computer Simulation, Image Processing, Computer-Assisted methods, Positron-Emission Tomography methods, Algorithms, Phantoms, Imaging
Abstract

Positron emission tomography (PET) is a widely utilized medical imaging modality that uses positron-emitting radiotracers to visualize biochemical processes in a living body. The spatiotemporal distribution of a radiotracer is estimated by detecting the coincidence photon pairs generated through positron annihilations. In human tissue, about 40% of the positrons form positroniums prior to the annihilation. The lifetime of these positroniums is influenced by the microenvironment in the tissue and could provide valuable information for better understanding of disease progression and treatment response. Currently, there are few methods available for reconstructing high-resolution lifetime images in practical applications. This paper presents an efficient statistical image reconstruction method for positronium lifetime imaging (PLI). We also analyze the random triple-coincidence events in PLI and propose a correction method for random events, which is essential for real applications. Both simulation and experimental studies demonstrate that the proposed method can produce lifetime images with high numerical accuracy, low variance, and resolution comparable to that of the activity images generated by a PET scanner with currently available time-of-flight resolution.

Published
2024
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99. Feasibility of the J-PET to monitor the range of therapeutic proton beams.

Author

Baran J, Borys D, Brzeziński K, Gajewski J, Silarski M, Chug N, Coussat A, Czerwiński E, Dadgar M, Dulski K, Eliyan KV, Gajos A, Kacprzak K, Kapłon Ł, Klimaszewski K, Konieczka P, Kopeć R, Korcyl G, Kozik T, Krzemień W, Kumar D, Lomax AJ, McNamara K, Niedźwiecki S, Olko P, Panek D, Parzych S, Perez Del Rio E, Raczyński L, Simbarashe M, Sharma S, Shivani, Shopa RY, Skóra T, Skurzok M, Stasica P, Stępień EŁ, Tayefi K, Tayefi F, Weber DC, Winterhalter C, Wiślicki W, Moskal P, and Ruciński A

Subjects
Feasibility Studies, Positron-Emission Tomography, Phantoms, Imaging, Monte Carlo Method, Protons, Proton Therapy methods
Abstract

Purpose: The aim of this work is to investigate the feasibility of the Jagiellonian Positron Emission Tomography (J-PET) scanner for intra-treatment proton beam range monitoring., Methods: The Monte Carlo simulation studies with GATE and PET image reconstruction with CASToR were performed in order to compare six J-PET scanner geometries. We simulated proton irradiation of a PMMA phantom with a Single Pencil Beam (SPB) and Spread-Out Bragg Peak (SOBP) of various ranges. The sensitivity and precision of each scanner were calculated, and considering the setup's cost-effectiveness, we indicated potentially optimal geometries for the J-PET scanner prototype dedicated to the proton beam range assessment., Results: The investigations indicate that the double-layer cylindrical and triple-layer double-head configurations are the most promising for clinical application. We found that the scanner sensitivity is of the order of 10 -5 coincidences per primary proton, while the precision of the range assessment for both SPB and SOBP irradiation plans was found below 1 mm. Among the scanners with the same number of detector modules, the best results are found for the triple-layer dual-head geometry. The results indicate that the double-layer cylindrical and triple-layer double-head configurations are the most promising for the clinical application, CONCLUSIONS:: We performed simulation studies demonstrating that the feasibility of the J-PET detector for PET-based proton beam therapy range monitoring is possible with reasonable sensitivity and precision enabling its pre-clinical tests in the clinical proton therapy environment. Considering the sensitivity, precision and cost-effectiveness, the double-layer cylindrical and triple-layer dual-head J-PET geometry configurations seem promising for future clinical application., Competing Interests: Declaration of competing interest The Authors declare no conflict of interest., (Copyright © 2024 Associazione Italiana di Fisica Medica e Sanitaria. Published by Elsevier Ltd. All rights reserved.)

Published
2024
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100. Discrete symmetries tested at 10 -4 precision using linear polarization of photons from positronium annihilations.

Author

Moskal P, Czerwiński E, Raj J, Bass SD, Beyene EY, Chug N, Coussat A, Curceanu C, Dadgar M, Das M, Dulski K, Gajos A, Gorgol M, Hiesmayr BC, Jasińska B, Kacprzak K, Kaplanoglu T, Kapłon Ł, Klimaszewski K, Konieczka P, Korcyl G, Kozik T, Krzemień W, Kumar D, Moyo S, Mryka W, Niedźwiecki S, Parzych S, Del Río EP, Raczyński L, Sharma S, Choudhary S, Shopa RY, Silarski M, Skurzok M, Stępień EŁ, Tanty P, Ardebili FT, Ardebili KT, Eliyan KV, and Wiślicki W

Abstract

Discrete symmetries play an important role in particle physics with violation of CP connected to the matter-antimatter imbalance in the Universe. We report the most precise test of P, T and CP invariance in decays of ortho-positronium, performed with methodology involving polarization of photons from these decays. Positronium, the simplest bound state of an electron and positron, is of recent interest with discrepancies reported between measured hyperfine energy structure and theory at the level of 10 -4 signaling a need for better understanding of the positronium system at this level. We test discrete symmetries using photon polarizations determined via Compton scattering in the dedicated J-PET tomograph on an event-by-event basis and without the need to control the spin of the positronium with an external magnetic field, in contrast to previous experiments. Our result is consistent with QED expectations at the level of 0.0007 and one standard deviation., (© 2024. The Author(s).)

Published
2024
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