211 results on '"Duodenal Diseases drug therapy"'
Search Results
52. Successful palliation of diarrhea owing to malignant duodenocolic fistula by octreotide.
- Author
-
Giridhar V, Kumar S, Chethan K, and Seetharam P
- Subjects
- Colonic Diseases complications, Diarrhea etiology, Duodenal Diseases complications, Female, Humans, Intestinal Fistula complications, Middle Aged, Palliative Care, Rectal Neoplasms therapy, Colonic Diseases drug therapy, Diarrhea drug therapy, Duodenal Diseases drug therapy, Gastrointestinal Agents therapeutic use, Intestinal Fistula drug therapy, Octreotide therapeutic use, Rectal Neoplasms complications
- Published
- 2009
53. [Male with advanced HIV infection, diarrhea, and swelling of the legs].
- Author
-
Rodríguez-Gómez FJ, Chinchón D, Ramos M, and Pujol E
- Subjects
- AIDS-Related Opportunistic Infections complications, AIDS-Related Opportunistic Infections drug therapy, Anti-Bacterial Agents therapeutic use, Anti-HIV Agents therapeutic use, Bone Marrow Diseases diagnosis, Bone Marrow Diseases drug therapy, Bone Marrow Diseases microbiology, Diarrhea microbiology, Duodenal Diseases diagnosis, Duodenal Diseases drug therapy, Duodenal Diseases microbiology, Enteral Nutrition, Humans, Hypotension etiology, Leg, Male, Middle Aged, Mycobacterium avium Complex isolation & purification, Mycobacterium avium-intracellulare Infection complications, Mycobacterium avium-intracellulare Infection drug therapy, Trimethoprim, Sulfamethoxazole Drug Combination therapeutic use, AIDS-Related Opportunistic Infections diagnosis, Diarrhea etiology, Edema etiology, Mycobacterium avium-intracellulare Infection diagnosis
- Published
- 2009
- Full Text
- View/download PDF
54. A rare case of duodenal immunoglobulin m infiltration in a patient with chronic lymphocytic leukemia.
- Author
-
Narang TK, Schnoll-Sussman FH, Yantiss R, Ely SA, Alyea EP 3rd, and Pochapin MB
- Subjects
- Biopsy, Needle, Budesonide therapeutic use, Diarrhea diagnosis, Diarrhea etiology, Duodenal Diseases drug therapy, Duodenoscopy methods, Follow-Up Studies, Humans, Immunohistochemistry, Intestinal Mucosa immunology, Intestinal Mucosa pathology, Leukemia, Lymphocytic, Chronic, B-Cell diagnosis, Leukemic Infiltration diagnosis, Male, Middle Aged, Rare Diseases, Risk Assessment, Treatment Outcome, Duodenal Diseases etiology, Duodenal Diseases pathology, Immunoglobulin M metabolism, Leukemia, Lymphocytic, Chronic, B-Cell complications, Leukemic Infiltration pathology
- Published
- 2009
- Full Text
- View/download PDF
55. Duodenopancreatic fistula complicating upper gastrointestinal Crohn's disease: successful treatment with infliximab.
- Author
-
Pajares JA, Hernández L, Menchén P, and Menchén L
- Subjects
- Adult, Crohn Disease diagnosis, Crohn Disease surgery, Dose-Response Relationship, Drug, Drug Administration Schedule, Duodenal Diseases drug therapy, Duodenal Diseases etiology, Follow-Up Studies, Humans, Infliximab, Intestinal Fistula etiology, Male, Pancreatic Fistula etiology, Risk Assessment, Treatment Outcome, Antibodies, Monoclonal therapeutic use, Crohn Disease complications, Intestinal Fistula drug therapy, Pancreatic Fistula drug therapy
- Published
- 2009
- Full Text
- View/download PDF
56. A case of duodenal Entamoeba histolytica.
- Author
-
Feagins LA, Chan V, and Spechler SJ
- Subjects
- AIDS-Related Opportunistic Infections drug therapy, AIDS-Related Opportunistic Infections pathology, Adult, Amebicides therapeutic use, Animals, Biopsy, Drug Administration Schedule, Drug Therapy, Combination, Duodenal Diseases drug therapy, Duodenal Diseases pathology, Duodenal Ulcer diagnosis, Duodenal Ulcer drug therapy, Duodenal Ulcer pathology, Duodenum pathology, Dysentery, Amebic drug therapy, Dysentery, Amebic pathology, Humans, Intestinal Mucosa pathology, Male, Metronidazole therapeutic use, Paromomycin therapeutic use, AIDS-Related Opportunistic Infections diagnosis, Duodenal Diseases diagnosis, Duodenoscopy, Dysentery, Amebic diagnosis, Entamoeba histolytica
- Published
- 2009
- Full Text
- View/download PDF
57. Acute gastroduodenal injury after ingestion of diluted herbicide pendimethalin.
- Author
-
Tsukada K, Azuhata H, Katoh H, and Kuwano H
- Subjects
- Acute Disease, Aged, Duodenal Diseases drug therapy, Humans, Male, Stomach Diseases drug therapy, Taiwan, Accidents, Home, Aniline Compounds toxicity, Anti-Ulcer Agents therapeutic use, Duodenal Diseases chemically induced, Herbicides toxicity, Omeprazole therapeutic use, Proton Pump Inhibitors therapeutic use, Stomach Diseases chemically induced
- Abstract
The herbicide, pendimethalin, is used worldwide, but its acute toxicity is not yet widely known. There have been some reported acute pendimethalin poisoning cases in humans and most of them intentionally ingested the concentrated formulation. We describe a 73-year-old man who developed corrosive gastroduodenal injury after accidental ingestion of the diluted (300 times with water) pendimethalin formulation. He had a history of reflux oesophagitis and had been taking omeprazol (10 mg/day) for a year. He consumed alcohol two hours after the accidental ingestion and then had nausea and epigastric pain. Endoscopy performed three days post-exposure revealed gastroduodenal injury. As he had consumed alcohol every day for years and had no history of gastroduodenal ulcer, the accidental ingestion may be associated with this injury. He was successfully treated by increasing his dosage of omeprazol (20 mg/day) for two weeks. This case indicates that ingestion of a small quantity of pendimethalin can provoke gastroduodenal injury.
- Published
- 2009
58. Electronic clinical challenges and images in GI. Image 1.
- Author
-
Bahamonde LG, Grosman I, and Bernstein DE
- Subjects
- Aged, Anti-Bacterial Agents therapeutic use, Diverticulitis complications, Diverticulitis drug therapy, Duodenal Diseases complications, Duodenal Diseases drug therapy, Duodenum diagnostic imaging, Female, Humans, Intestinal Perforation etiology, Tomography, X-Ray Computed, Diverticulitis diagnosis, Duodenal Diseases diagnosis, Intestinal Perforation diagnosis
- Published
- 2009
- Full Text
- View/download PDF
59. Heterotropic gastric tissue in duodenal bulb mimicking duodenal cancer: an unusual duodenal lesion.
- Author
-
Kibria R, Butt S, Ali SA, and Akram S
- Subjects
- Calcium Channel Blockers therapeutic use, Diagnosis, Differential, Duodenal Diseases drug therapy, Humans, Male, Middle Aged, Choristoma pathology, Duodenal Diseases pathology, Duodenal Neoplasms pathology, Stomach
- Published
- 2009
- Full Text
- View/download PDF
60. Duodenal mucosal nodularity in Strongyloides stercoralis infection.
- Author
-
Somani SK, Goyal R, and Awasthi G
- Subjects
- Animals, Antiparasitic Agents therapeutic use, Duodenal Diseases drug therapy, Duodenal Diseases pathology, Duodenum pathology, Endoscopy, Humans, Ivermectin therapeutic use, Male, Strongylida Infections parasitology, Strongyloides stercoralis isolation & purification, Young Adult, Duodenal Diseases diagnosis, Duodenal Diseases parasitology, Strongylida Infections diagnosis, Strongylida Infections drug therapy
- Abstract
A 22-year-old man presented with a two-year history of colicky upper abdominal and dyspnoea. His absolute eosinophil count (AEC) was 980/mm3. Chest x-ray revealed hilar prominence. An upper gastrointestinal endoscopy showed marked oedema and nodularity of duodenal mucosal folds. Duodenal biopsy disclosed heavy lymphoplasmacytic infiltrates in the lamina propria and sheets of eosinophils and rhabdtiform larvae of Strongyloides stercoralis in the crypts. The patient was not on steroids and his HIV ELISA was nonreactive. His IgG ELISA for Strongyloides stercoralis was positive. Nodular duodenal mucosa may thus be seen with Strongyloides stercoralis infection.
- Published
- 2009
61. Primary duodenal tuberculosis: a case report.
- Author
-
Lamberty G, Pappalardo E, Dresse D, and Denoël A
- Subjects
- Abdominal Pain etiology, Adult, Antitubercular Agents therapeutic use, Duodenal Diseases drug therapy, Duodenal Diseases microbiology, Guinea ethnology, Heartburn etiology, Humans, Male, Tuberculosis, Gastrointestinal drug therapy, Young Adult, Duodenal Diseases diagnosis, Tuberculosis, Gastrointestinal diagnosis
- Abstract
Gastroduodenal tuberculosis (TB) is a rare condition and is often associated with pulmonary TB. We report the case of a primary duodenal TB in an immunocompetent patient without evidence of pulmonary TB. Diagnosis of this disease is difficult and is often confused with chronic peptic ulcer disease. Literature data concerning this challenging diagnosis are analysed.
- Published
- 2008
- Full Text
- View/download PDF
62. [A method for the conservative treatment of patients with erosive and ulcerative lesions in the oesophagogastroduodenal system with the use of spa factors and medications. A new medical technology].
- Author
-
Osipov IuS, Efimenko NV, Uvarova NG, Kaĭsinova AS, Ereshova IG, Mosiiants LM, Fedorova TE, and Chubina IA
- Subjects
- Anti-Bacterial Agents therapeutic use, Balneology, Duodenal Diseases drug therapy, Esophageal Diseases drug therapy, Health Resorts, Humans, Patents as Topic, Stomach Diseases drug therapy, Ulcer drug therapy, Duodenal Diseases therapy, Esophageal Diseases therapy, Stomach Diseases therapy, Ulcer therapy
- Published
- 2008
63. Nodular lymphoid hyperplasia by Giardia lamblia.
- Author
-
Pérez-Roldán F, Mate-Valdezate A, Villafáñez-García MC, González Carro P, and Legaz Huidobro ML
- Subjects
- Animals, Antigens, Protozoan immunology, Biopsy, Needle, Duodenal Diseases drug therapy, Duodenal Diseases immunology, Duodenal Diseases parasitology, Duodenoscopy, Female, Follow-Up Studies, Giardia lamblia immunology, Giardiasis drug therapy, Giardiasis immunology, Humans, Hyperplasia pathology, Immunohistochemistry, Intestinal Mucosa parasitology, Intestinal Mucosa pathology, Lymphatic Diseases parasitology, Lymphatic Diseases pathology, Metronidazole therapeutic use, Middle Aged, Risk Assessment, Treatment Outcome, Duodenal Diseases diagnosis, Giardia lamblia isolation & purification, Giardiasis diagnosis, Immunoglobulin A immunology, Lymphatic Diseases diagnosis
- Published
- 2008
- Full Text
- View/download PDF
64. [NSAID-gastropathy: state-of-the-art therapy optimization capabilities in outpatient practice].
- Author
-
Burkov SG, Arutiunov AT, Gurova NIu, Lobanova EG, Nikiforov PA, Okoemov MN, Cherezova IN, and Chugunnikova LI
- Subjects
- Adult, Aged, Ambulatory Care, Drug Administration Schedule, Duodenal Diseases chemically induced, Duodenal Diseases diagnosis, Female, Humans, Male, Middle Aged, Stomach Diseases chemically induced, Stomach Diseases diagnosis, Treatment Outcome, Anti-Inflammatory Agents, Non-Steroidal adverse effects, Anti-Ulcer Agents administration & dosage, Anti-Ulcer Agents therapeutic use, Duodenal Diseases drug therapy, Omeprazole administration & dosage, Omeprazole therapeutic use, Stomach Diseases drug therapy
- Published
- 2008
65. Duodenal thrombotic thrombocytopenic purpura.
- Author
-
Owens DJ and Jung B
- Subjects
- Adult, Biopsy, Needle, Bone Marrow Transplantation methods, Drug Therapy, Combination, Duodenal Diseases drug therapy, Duodenal Diseases etiology, Duodenoscopy methods, Female, Follow-Up Studies, Humans, Leukemia, Myelomonocytic, Acute diagnosis, Purpura, Thrombotic Thrombocytopenic drug therapy, Purpura, Thrombotic Thrombocytopenic etiology, Risk Assessment, Transplantation, Homologous, Treatment Outcome, Bone Marrow Transplantation adverse effects, Duodenal Diseases diagnosis, Leukemia, Myelomonocytic, Acute therapy, Purpura, Thrombotic Thrombocytopenic diagnosis
- Published
- 2007
- Full Text
- View/download PDF
66. Endoscopic extraction of Fasciolopsis buski.
- Author
-
Murugesh M, Veerendra S, Madhu S, Kude S, Amrapurkar AD, Rathi UU, and Rathi PM
- Subjects
- Adult, Animals, Duodenal Diseases drug therapy, Duodenal Diseases parasitology, Female, Humans, Praziquantel therapeutic use, Pregnancy, Pregnancy Complications, Parasitic drug therapy, Pregnancy Complications, Parasitic parasitology, Trematode Infections drug therapy, Trematode Infections parasitology, Duodenal Diseases therapy, Duodenoscopy, Fasciolidae, Pregnancy Complications, Parasitic therapy, Trematode Infections therapy
- Published
- 2007
- Full Text
- View/download PDF
67. Influence of nifedypine on the hyperalgesic action of duodenal distention in sheep.
- Author
-
Kania BF and Lewicki S
- Subjects
- Analgesia veterinary, Animals, Dose-Response Relationship, Drug, Duodenal Diseases drug therapy, Female, Gastrointestinal Motility drug effects, Hyperalgesia drug therapy, Sheep, Calcium Channel Blockers therapeutic use, Duodenal Diseases veterinary, Hyperalgesia veterinary, Nifedipine therapeutic use, Sheep Diseases drug therapy
- Abstract
The aim of this study was to determine the influence of nifedypine--competitive antagonist of voltage-gated dependent L-type Ca2+ channels (VGCCs)--on inhibition of reticulo-ruminal motility, heart beats, respiratory rates and other nociceptive behavior symptoms caused by duodenal distention (DD). The animals, which were under general anesthesia, had duodenal and ruminal fistulas and intracerebroventriculary (i.c.v.) cannulas inserted into the lateral ventricle. Reticulo-ruminal contractions were recorded mechanographically using an electronic tensometer. The frequency of reticulo-ruminal contractions was determined by the number of mechanograms with 5 min intervals prior to and after DD (for 180 min). The duodenal distention was performed using a rubber balloon (10 cm length), which was inserted via the duodenal fistula and filled with 40 ml water. Five min DD caused immediate and almost complete inhibition of reticulo-ruminal contractions, nociceptive behavior symptoms, tachycardia and hyperventilation. Nifedypine per se did not change the reticulo-ruminal motility, general behavior or clinical symptoms; however, doses of 1 and 2 mg of nifedypine in toto infused i.c.v 10 minutes before DD prevented all signs of reticulo-ruminal disorders, as well as the general nociceptive behavior. Nifedypine inhibited particularly clinical symptoms such as tachycardia and hyperventilation. The observed antinociceptive action of VGCCs type-L blockers suggests that these channels play a crucial role in the modulation of acute visceral hyperalgesia. Nifedipine can be useful in controlling acute visceral pain associated, for example, with different kinds of colic.
- Published
- 2007
68. [Fistulizing gastroduodenal Crohn's disease histologically mimicking MALT lymphoma].
- Author
-
Molina Infante J, García Abadía E, Conde Gacho P, and Lucena Flores A
- Subjects
- Crohn Disease drug therapy, Crohn Disease pathology, Diagnosis, Differential, Duodenal Diseases drug therapy, Duodenal Diseases pathology, Gastric Fistula drug therapy, Gastric Fistula pathology, Glucocorticoids therapeutic use, Humans, Intestinal Fistula drug therapy, Intestinal Fistula pathology, Intestinal Mucosa pathology, Male, Middle Aged, Prednisone therapeutic use, Treatment Outcome, Crohn Disease complications, Duodenal Diseases etiology, Gastric Fistula etiology, Intestinal Fistula etiology
- Published
- 2006
- Full Text
- View/download PDF
69. [Carbonaceous arsenious mineral water of Chvizhepsinsky spring and prospects of its use in rehabilitation of patients with gastroduodenal disease in Sochi sanatoria].
- Author
-
Mamishev SN, Georgiadi-Avdienko KA, Khodasevich LS, Utekhina VP, Ryzhkov NT, Kandelis GV, Tsabiev SM, Nugzarova SS, and Bekhterev VN
- Subjects
- Humans, Russia, Arsenic analysis, Duodenal Diseases drug therapy, Health Resorts, Mineral Waters analysis, Mineral Waters therapeutic use, Stomach Diseases drug therapy
- Published
- 2006
70. [Prevalence of polyresistance to antibiotics among Helicobacter pylori strains isolated from patients with gastroduodenal zone diseases].
- Author
-
Khetsuriani ShG, Rachvelishvili BKh, and Khetsuriani KG
- Subjects
- Biopsy, Duodenal Diseases drug therapy, Duodenal Diseases pathology, Helicobacter Infections drug therapy, Helicobacter Infections pathology, Helicobacter pylori isolation & purification, Humans, In Vitro Techniques, Intestinal Mucosa microbiology, Intestinal Mucosa pathology, Stomach Diseases drug therapy, Stomach Diseases pathology, Anti-Bacterial Agents therapeutic use, Drug Resistance, Multiple, Bacterial, Duodenal Diseases microbiology, Helicobacter Infections microbiology, Helicobacter pylori drug effects, Stomach Diseases microbiology
- Abstract
Unlabelled: To study prevalence of polyresistance (PR) among the strains of Helicobacter pylori isolated from patients with chronic gastritis, gastroduodenal ulcer and gastric cancer in Georgia. Material and methods. Biopsies of gastric mucosa and resection material were studied in 206patients with gastroduodenal zone diseases for identification of H. pylori (HP) and PR strains of HP. Results. The number of antibiotics involved in development of polyresistant strains varies from 3 to 8. The greatest number of strains (28.57 +/- 1.06%) develop PR to 5 antibiotics, the least--to 8 antibiotics., Conclusion: PR prevalence among HP strains is 35.25 +/- 4.05%. PR is most frequently seen to metronidasol and oxacilline, least frequently--to amoxicilline and clarithromycin.
- Published
- 2006
71. Normalization of oesophageal pH does not guarantee control of duodenogastro-oesophageal reflux in Barrett's oesophagus.
- Author
-
Todd JA, Basu KK, and de Caestecker JS
- Subjects
- Aged, Esophagoscopy, Esophagus physiology, Female, Gastroesophageal Reflux complications, Humans, Hydrogen-Ion Concentration, Male, Middle Aged, Proton Pump Inhibitors, Anti-Ulcer Agents therapeutic use, Barrett Esophagus complications, Duodenal Diseases drug therapy, Gastric Acid physiology, Gastroesophageal Reflux prevention & control, Omeprazole therapeutic use
- Abstract
Background: Proton-pump inhibitors are effective at preventing the acid component of gastro-oesophageal refluxate from entering the oesophagus. It is not clear whether proton-pump inhibitors prevent duodenogastro-oesophageal reflux., Aim: To measure oesophageal exposure to duodenogastro-oesophageal refluxate while on proton-pump inhibitors in patients with Barrett's oesophagus., Methods: Twenty-five patients (23 male) with Barrett's oesophagus underwent 24 h oesophageal pH and Bilitec 2000 monitoring while on omeprazole 40 mg/day (n = 19) or omeprazole 60 mg/day (n = 6). All patients were undergoing argon plasma ablation of their Barrett's epithelium as part of a clinical trial and the Bilitec measurements were only carried out after the ablation had been completed., Results: 20 of 25 (80%) patients had a normal oesophageal pH profile. Fifteen of the 25 (60%) had abnormal oesophageal exposure to bile as measured by Bilitec 2000. Of the 20 patients who had a normal 24 h oesophageal pH profile, 11 (55%) had pathological exposure to bile in their oesophagus., Conclusion: Complete acid suppression does not guarantee elimination of duodenogastro-oesophageal reflux.
- Published
- 2005
- Full Text
- View/download PDF
72. Refractory enterovesical and duodenocolic fistulas in Crohn's disease successfully managed with tacrolimus.
- Author
-
Fukuda A, Nakase H, Seno H, Nabeshima M, Sawada M, and Chiba T
- Subjects
- Adult, Colonic Diseases complications, Colonic Diseases diagnosis, Colonoscopy, Crohn Disease drug therapy, Duodenal Diseases complications, Duodenal Diseases diagnosis, Female, Follow-Up Studies, Humans, Immunosuppressive Agents administration & dosage, Injections, Intravenous, Intestinal Fistula complications, Intestinal Fistula diagnosis, Tacrolimus administration & dosage, Colonic Diseases drug therapy, Crohn Disease complications, Duodenal Diseases drug therapy, Immunosuppressive Agents therapeutic use, Intestinal Fistula drug therapy, Tacrolimus therapeutic use
- Published
- 2005
- Full Text
- View/download PDF
73. Management of perforated duodenal diverticula.
- Author
-
Marhin WW and Amson BJ
- Subjects
- Anti-Infective Agents therapeutic use, Diverticulum complications, Diverticulum diagnostic imaging, Diverticulum drug therapy, Diverticulum surgery, Drug Therapy, Combination, Duodenal Diseases complications, Duodenal Diseases diagnostic imaging, Duodenal Diseases drug therapy, Duodenal Diseases surgery, Female, Humans, Intestinal Perforation diagnostic imaging, Intestinal Perforation drug therapy, Intestinal Perforation etiology, Intestinal Perforation surgery, Middle Aged, Retroperitoneal Space diagnostic imaging, Tomography, X-Ray Computed, Diverticulum therapy, Duodenal Diseases therapy, Intestinal Perforation therapy
- Published
- 2005
74. Image of the month. Strongyloides stercoralis hyperinfection and syndrome of inappropriate secretion of antidiuretic hormone.
- Author
-
Seet RC, Gong LL, and Tambyath PA
- Subjects
- Animals, Antinematodal Agents therapeutic use, Duodenal Diseases drug therapy, Humans, Inappropriate ADH Syndrome drug therapy, Ivermectin therapeutic use, Lung Diseases drug therapy, Male, Middle Aged, Strongyloidiasis drug therapy, Duodenal Diseases diagnosis, Inappropriate ADH Syndrome diagnosis, Lung Diseases diagnosis, Strongyloides stercoralis, Strongyloidiasis diagnosis
- Published
- 2005
- Full Text
- View/download PDF
75. Clinical efficacy and pharmacokinetics of montelukast in dyspeptic children with duodenal eosinophilia.
- Author
-
Friesen CA, Kearns GL, Andre L, Neustrom M, Roberts CC, and Abdel-Rahman SM
- Subjects
- Acetates pharmacokinetics, Adolescent, Child, Cross-Over Studies, Cyclopropanes, Double-Blind Method, Duodenal Diseases metabolism, Dyspepsia metabolism, Eosinophilia metabolism, Female, Humans, Intestinal Mucosa cytology, Leukotriene Antagonists pharmacokinetics, Male, Pain etiology, Quinolines pharmacokinetics, Sulfides, Treatment Outcome, Acetates therapeutic use, Duodenal Diseases drug therapy, Dyspepsia drug therapy, Eosinophilia drug therapy, Leukotriene Antagonists therapeutic use, Quinolines therapeutic use
- Abstract
Background: Montelukast, a competitive cysteinyl leucotriene-1 receptor antagonist, reduces airway eosinophilia in asthmatics. We evaluated the effect of this drug in children with eosinophilic duodenitis, defined histologically as duodenal mucosa with peak eosinophil count of more than 10 eosinophils/hpf., Methods: Forty children and adolescents (6-18 yr) with dyspepsia and duodenal eosinophilia were enrolled in a double blind, randomized, placebo-controlled, cross-over study of monteleukast therapy. Subjects were randomized to receive either 10 mg montelukast or an identical placebo once daily and were evaluated on day 14 for symptomatic and biochemical responses. Subjects were also randomized to one of two blood sampling schemes to evaluate montelukast pharmacokinetics., Results: Using a post treatment global pain assessment, a positive clinical response was observed in 62.1% of patients receiving montelukast compared with 32.4% on placebo (p < 0.02). Pain assessment score deteriorated in 45% of montelukast responders (5/11) after cross-over to placebo and improved in 62% (8/13) of placebo non-responders on cross-over to montelukast. In patients with peak duodenal eosinophil counts between 20-29/hpf (n=19), a positive pain assessment response was observed in 84% of patients receiving montelukast compared to 42% receiving placebo (p < 0.01). Response rate did not differ by age, gender or histologic findings at baseline. Pharmacokinetic analysis yielded parameter estimates for absorption rate constant (Ka), apparent volume of distribution (Vd/F) and elimination rate constant (Kel) of 0.42 h, 0.19 L/kg and 0.26 h, respectively. The relative extent of systemic drug exposure was comparable to that observed in previous pediatric investigations with similar weight-adjusted montelukast doses. Neither dose nor calculated drug exposure were associated with the level of post treatment pain assessment or the change in biochemical markers., Conclusions: These data suggest a beneficial role for montelukast in the treatment of pediatric patients with dyspepsia associated with duodenal eosinophilia.
- Published
- 2004
- Full Text
- View/download PDF
76. [Undeveloped high intestinal fistulas as an urgent problem of modern surgery].
- Author
-
Rudin EP, Ermolov AS, Bogdanov AV, and Mironov AS
- Subjects
- Adolescent, Adult, Aged, Anastomosis, Surgical mortality, Duodenal Diseases drug therapy, Duodenal Diseases etiology, Duodenal Diseases mortality, Duodenum surgery, Humans, Intestinal Fistula drug therapy, Intestinal Fistula etiology, Intestinal Fistula mortality, Jejunal Diseases drug therapy, Jejunal Diseases etiology, Jejunal Diseases mortality, Jejunoileal Bypass mortality, Middle Aged, Treatment Outcome, Duodenal Diseases surgery, Intestinal Fistula surgery, Jejunal Diseases surgery
- Abstract
Eighty-two cases of un formed high intestinal fistulas are analyzed. Degree of non-formation and volume of chymus loss are the main criteria determining treatment policy. Early surgery (one or two-sided switching of fistulas zone) is indicated in intestinal loss more then 600-700 ml per day or in complete fistula. Mezonnes surgery was un effective in the majority of cases. Special policy including trunk vagotomy, antrumectomy and plastic repair of the duodenal bulb permitted in the last years to avoid duodenal fistulas in the treatment of ulcer disease.
- Published
- 2004
77. Use of octreotide in the management of severe duodenal bleeding after unrelated-donor bone marrow transplantation.
- Author
-
Ohashi K, Sanaka M, Tanaka Y, Okuyama Y, Hiruma K, Akiyama H, and Sakamaki H
- Subjects
- Adult, Duodenal Diseases drug therapy, Duodenal Diseases etiology, Female, Gastrointestinal Hemorrhage etiology, Graft vs Host Disease complications, Humans, Tissue Donors, Bone Marrow Transplantation, Gastrointestinal Agents administration & dosage, Gastrointestinal Hemorrhage drug therapy, Leukemia, Myelogenous, Chronic, BCR-ABL Positive therapy, Octreotide administration & dosage
- Published
- 2003
- Full Text
- View/download PDF
78. Mortality study of 18 000 patients treated with omeprazole.
- Author
-
Bateman DN, Colin-Jones D, Hartz S, Langman M, Logan RF, Mant J, Murphy M, Paterson KR, Rowsell R, Thomas S, and Vessey M
- Subjects
- Adolescent, Adult, Aged, Aged, 80 and over, Child, Duodenal Diseases drug therapy, Esophageal Diseases drug therapy, Esophageal Diseases mortality, Esophageal Neoplasms mortality, Female, Gastrointestinal Neoplasms mortality, Humans, Male, Middle Aged, Proton Pump Inhibitors, Respiratory Tract Neoplasms mortality, Stomach Diseases drug therapy, Anti-Ulcer Agents adverse effects, Cause of Death, Enzyme Inhibitors adverse effects, Omeprazole adverse effects
- Abstract
Background: The long term safety of potent gastric acid suppressive therapy has yet to be established., Method: General practice record review at a median interval of 26 months followed by retrieval of details of all deaths within four years using the UK National Health Service Central Registers in 17 936 patients prescribed omeprazole in 1993-1995. Death rates were compared with general population rates., Results: Records of 17 489 patients (97.5%) were examined. A total of 12 703 patients received further scripts for antisecretory drugs, 8097 for omeprazole only (65.6%): 3097 patients have died. All cause mortality was higher in the first year (observed/expected (O/E) 1.44 (95% confidence intervals (CI) 1.34-1.55); p<0.0001) but had fallen to population expectation by the fourth year. There were significant mortality increases in the first year, falling to or below population expectation by the fourth year, for deaths ascribed to neoplasms (1.82 (95% CI 1.58-2.08); p<0.0001), circulatory diseases (1.27 (95% CI 1.13-1.43); p<0.0001), and respiratory diseases (1.37 (95% CI 1.12-1.64); p<0.001). Increased mortality ascribed to digestive diseases (2.56 (95% CI 1.87-3.43); p<0.0001) persisted, although reduced. Increased mortality rates for cancers of the stomach (4.06 (95% CI 2.60-6.04); p<0.0001), colon and rectum (1.40 (95% CI 0.84-2.18); p=0.075), and trachea, bronchus, and lung (1.64 (95% CI 1.19-2.19); p<0.01) seen in the first year had disappeared by the fourth year but that for cancer of the oesophagus had not (O/E 7.35 (95% CI 5.20-10.09) (p<0.0001) in year 1; 2.88 (95% CI 1.62-4.79) (p<0.001) in year 4). Forty of 78 patients dying of oesophageal cancer had the disease present at registration. Twenty seven of those remaining cases had clinical evidence of Barrett's disease, stricture, ulcer, or oesophagitis at registration (O/E 3.30 (95% CI 2.17-4.80)). Six deaths occurred in patients with hiatal hernia or reflux only (O/E 1.02 (95% CI 0.37-2.22)) and five in patients without oesophageal disease (O/E 0.77 (95% CI 0.25-1.80)). No relationships were detected with numbers of omeprazole scripts received., Conclusions: Increases in mortality associated with treatment are due to pre- existing illness, including pre-existing severe oesophageal disease. There was no evidence of an increased risk of oesophageal adenocarcinoma in those without oesophageal mucosal damage recorded at registration.
- Published
- 2003
- Full Text
- View/download PDF
79. A human case of Echinostoma hortense (Trematoda: Echinostomatidae) infection diagnosed by gastroduodenal endoscopy in Korea.
- Author
-
Cho CM, Tak WY, Kweon YO, Kim SK, Choi YH, Kong HH, and Chung DI
- Subjects
- Aged, Aged, 80 and over, Animals, Duodenal Diseases drug therapy, Duodenal Diseases parasitology, Echinostomiasis drug therapy, Echinostomiasis parasitology, Endoscopy, Gastrointestinal, Female, Fishes parasitology, Food Parasitology, Humans, Korea, Male, Praziquantel therapeutic use, Duodenal Diseases diagnosis, Echinostoma growth & development, Echinostomiasis diagnosis
- Abstract
A human Echinostoma hortense infection was diagnosed by gastroduodenoscopy. An 81-year-old Korean male, living in Yeongcheon-shi, Gyeongsangbuk-do and with epigastric discomfort of several days duration, was subjected to upper gastrointestinal endoscopy. He was in the habit of eating fresh water fish. Two live worms were found in the duodenal bulb area and were removed using an endoscopic forceps. Based on their morphological characteristics, the worms were identified as E. hortense. The patient was treated with praziquantel 10 mg/kg as a single dose. The source of the infection in this case remains unclear, but the fresh water fish consumed, including the loach, may have been the source. This is the second case of E. hortense infection diagnosed by endoscopy in Korea.
- Published
- 2003
- Full Text
- View/download PDF
80. [Lanreotide acetate may cure cystic dystrophy in heterotopic pancreas of the duodenal wall].
- Author
-
Basili E, Allemand I, Ville E, and Laugier R
- Subjects
- Choristoma pathology, Duodenal Diseases pathology, Humans, Male, Middle Aged, Pancreatic Cyst pathology, Somatostatin analogs & derivatives, Treatment Outcome, Anti-Inflammatory Agents, Non-Steroidal therapeutic use, Choristoma complications, Duodenal Diseases drug therapy, Pancreas, Pancreatic Cyst drug therapy, Peptides, Cyclic therapeutic use, Somatostatin therapeutic use
- Abstract
Cystic dystrophy in heterotopic pancreas of the duodenal wall is a rare but benign disease, associated in most of the cases with chronic pancreatitis. Treatment of this disease is controversial. We report here the use of a long-acting somatostatin synthetic stable analogue in the treatment of a cystic dystrophy in heterotopic pancreas of the duodenal wall: a 45-year-old man, hard drinker, was treated successfully during three months with lanreotide acetate; disappearance of cysts was confirmed by a computed tomography two months after the end of treatment.
- Published
- 2001
81. A prospective study of a one-week nonbismuth quadruple therapy for childhood Helicobacter pylori infection.
- Author
-
Chan KL, Zhou H, Ng DK, and Tam PK
- Subjects
- Adolescent, Adult, Amoxicillin administration & dosage, Anti-Bacterial Agents administration & dosage, Anti-Ulcer Agents administration & dosage, Child, Child, Preschool, Clarithromycin administration & dosage, Drug Administration Schedule, Drug Therapy, Combination, Duodenal Diseases diagnosis, Helicobacter Infections diagnosis, Humans, Metronidazole administration & dosage, Omeprazole administration & dosage, Penicillins administration & dosage, Prospective Studies, Stomach Diseases diagnosis, Duodenal Diseases drug therapy, Helicobacter Infections drug therapy, Helicobacter pylori, Stomach Diseases drug therapy
- Abstract
Purpose: In the eradication of Helicobacter pylori infection, a 1-week therapy improves patient compliance, but drug resistance may limit its efficacy. The effectiveness of the 1-week nonbismuth quadruple therapy was studied prospectively in children with proven H pylori infection in a population with a high rate of metronidazole resistance., Methods: All pediatric patients who presented to our institutions with acute and chronic upper gastrointestinal conditions requiring endoscopy from June 1997 to February 2000 were investigated prospectively for H pylori infection. Gastric biopsy specimens were analyzed with rapid urease test and histopathology, H pylori-positive children were treated with omeprazole, clarithromycin, amoxicillin, and metronidazole for 7 days. The result of treatment was assessed 1 month after treatment with endoscopy and biopsy. The same treatment was repeated for 2 weeks if H pylori was still present. In patients who needed a third endoscopy, their biopsy specimens were cultured to determine antibiotic sensitivity. Results were correlated with patients' symptoms and endoscopic findings., Results: Thirty-three children with acute (severe epigastric pain, n = 14; gastrointestinal bleeding, n = 9) and chronic (recurrent abdominal pain, n = 7; anemia, n = 3) conditions were treated for H pylori. Thirty-one (94%) were confirmed to have H pylori eradicated by a 1-week therapy, whereas 1 patient had eradication after a further 2-we'ek therapy (3.3%). The only unresponsive patient had H pylori resistant to both clarithromycin and metronidazole. All ulcers and erosions healed after the eradication of H pylori. Three patients had persistent recurrent abdominal pain despite H pylori eradication., Conclusions: The 1-week therapy with omeprazole, clarithromycin, amoxicillin, and metronidazole is an effective treatment of H pylori in children in a population with a high incidence of metronidazole resistant strain of H pylori. Peptic ulcers and erosions healed with the eradication of the bacteria., (Copyright 2001 by W.B. Saunders Company.)
- Published
- 2001
- Full Text
- View/download PDF
82. Impact of different therapeutic regimens on the outcome of patients with Crohn's disease of the upper gastrointestinal tract.
- Author
-
Miehsler W, Püspök A, Oberhuber T, and Vogelsang H
- Subjects
- 2-Pyridinylmethylsulfinylbenzimidazoles, Adult, Crohn Disease metabolism, Data Interpretation, Statistical, Disaccharides, Famotidine therapeutic use, Female, Humans, Lansoprazole, Male, Mannitol, Mesalamine therapeutic use, Middle Aged, Omeprazole analogs & derivatives, Permeability, Proton Pumps therapeutic use, Retrospective Studies, Treatment Outcome, Anti-Ulcer Agents therapeutic use, Crohn Disease drug therapy, Duodenal Diseases drug therapy, Esophageal Diseases drug therapy, Omeprazole therapeutic use, Stomach Diseases drug therapy
- Abstract
Background: To follow-up clinical and biochemical features in patients with Crohn's disease (CD) of the upper gastrointestinal (GI) tract and to evaluate the impact of different therapeutics on the outcome of these patients., Methods: 32 CD patients with endoscopically and histologically proven CD of the upper GI tract were included into this retrospective study. Gastroduodenal and intestinal permeability tests, inflammatory parameters, Crohn's Disease Activity Index (CDAI), and upper gastrointestinal complaint profile were sequentially assessed. These parameters were assessed at the beginning and followed up during therapies with antisecretory drugs, mesalamine, prednisolone, and azathioprine., Results: Symptoms responded to antisecretory drugs. Gastroduodenal permeability increased under mesalamine. Gastroduodenal and intestinal permeability as well as CDAI decreased under prednisolone. Under azathioprine, gastroduodenal and intestinal permeability, CDAI, and C-reactive protein decreased.
- Published
- 2001
- Full Text
- View/download PDF
83. Gastric outlet obstruction due to duodenal tuberculosis: a case report.
- Author
-
Moirangthem GS, Singh NS, Bhattacharya KN, Chito TH, and Singh LD
- Subjects
- Adolescent, Antitubercular Agents therapeutic use, Duodenal Diseases drug therapy, Duodenal Diseases surgery, Gastric Outlet Obstruction surgery, Humans, Male, Tuberculosis, Gastrointestinal drug therapy, Tuberculosis, Gastrointestinal surgery, Tuberculosis, Lymph Node drug therapy, Tuberculosis, Lymph Node surgery, Duodenal Diseases complications, Gastric Outlet Obstruction etiology, Tuberculosis, Gastrointestinal complications, Tuberculosis, Lymph Node complications
- Abstract
A 17-year-old boy was operated on for gastric outlet obstruction; laparotomy revealed a mass with nodules in the first part of the duodenum and multiple mesenteric lymph nodes. The histopathological examination of the duodenal mass and the lymph nodes showed caseating tuberculosis. Because of the rarity of duodenal tuberculosis, the case is reported herewith.
- Published
- 2001
84. [Abdominal tuberculosis: a rare differential diagnosis of pancreatic carcinoma].
- Author
-
Enders M, Zuber MA, Venzke T, Köhler M, Zeitz M, and Duchmann R
- Subjects
- Aged, Antitubercular Agents therapeutic use, Biopsy, Needle, Cholangiopancreatography, Endoscopic Retrograde, Diagnosis, Differential, Duodenal Diseases drug therapy, Female, Follow-Up Studies, Humans, Pancreas pathology, Pancreatic Diseases drug therapy, Radiography, Abdominal, Radiography, Thoracic, Time Factors, Tomography, X-Ray Computed, Tuberculin Test, Tuberculosis drug therapy, Tuberculosis, Gastrointestinal drug therapy, Duodenal Diseases diagnosis, Pancreatic Diseases diagnosis, Pancreatic Neoplasms diagnosis, Tuberculosis diagnosis, Tuberculosis, Gastrointestinal diagnosis
- Abstract
History and Admission Findings: A 79-year-old local resident, presenting with abdominal pain, sweating and weight loss and suspected of having cancer of the pancreas was referred for diagnosis and treatment. Physical examination was negative except for pain on pressure over the right upper abdomen and the epigastrium., Investigations: Erythrocyte sedimentation rate was increased; as were the transaminases and cholestasis parameters. Ultrasonography and computed tomography of the abdomen revealed an echo-poor mass with cystic areas in the region of the head of the pancreas, as well as extra- and intrahepatic dilatation of the biliary tract. Endoscopic retrograde cholangiopancreatography failed to demonstrate a ductal pancreatic carcinoma. Biopsies of a macroscopically peculiar-looking duodenal ulcer demonstrated a noncaseous epithelioid granuloma. A fine-needle biopsy was performed for further diagnosis., Diagnosis, Treatment and Course: Histological examination of the needle biopsy revealed a caseous granuloma and acid-fast bacteria. The tuberculin test (GTI) was strongly positive (14-15 mm), indicating tuberculosis of the pancreas and duodenum. Multiple tuberculostatics rapidly improved the patient's symptoms, and the further course was without complications., Conclusion: Tuberculosis should be included in the differential diagnosis of consumptive disease with an atypical presentation, especially because treatment could well be curative.
- Published
- 2001
- Full Text
- View/download PDF
85. Gastroduodenal tuberculosis presenting with massive hematemesis in a pregnant woman.
- Author
-
Sharma BC, Prasad H, Bhasin DK, and Singh K
- Subjects
- Adult, Antitubercular Agents therapeutic use, Biopsy, Needle, Duodenal Diseases complications, Duodenal Diseases drug therapy, Endoscopy, Gastrointestinal, Female, Humans, India, Pregnancy, Severity of Illness Index, Stomach Diseases complications, Stomach Diseases drug therapy, Treatment Outcome, Tuberculosis, Gastrointestinal complications, Tuberculosis, Gastrointestinal drug therapy, Duodenal Diseases diagnosis, Hematemesis etiology, Pregnancy Complications, Infectious diagnosis, Pregnancy Outcome, Stomach Diseases diagnosis, Tuberculosis, Gastrointestinal diagnosis
- Published
- 2000
- Full Text
- View/download PDF
86. Finding the optimum treatment for Helicobacter pylori.
- Author
-
Moayyedi P
- Subjects
- Duodenal Diseases drug therapy, Evaluation Studies as Topic, Helicobacter Infections microbiology, Helicobacter pylori isolation & purification, Humans, Stomach Ulcer drug therapy, Treatment Outcome, Anti-Bacterial Agents, Drug Therapy, Combination therapeutic use, Duodenal Diseases microbiology, Helicobacter Infections drug therapy, Helicobacter pylori drug effects, Stomach Ulcer microbiology
- Published
- 2000
- Full Text
- View/download PDF
87. Prevention of hemorrhage from intradiverticular ulcer in the duodenum by Helicobacter pylori eradication.
- Author
-
Sugimoto M, Kajimura M, Hanai H, and Kaneko E
- Subjects
- Aged, Amoxicillin therapeutic use, Anti-Bacterial Agents therapeutic use, Anti-Ulcer Agents therapeutic use, Clarithromycin therapeutic use, Diverticulum drug therapy, Drug Therapy, Combination therapeutic use, Duodenal Diseases drug therapy, Duodenal Ulcer drug therapy, Female, Follow-Up Studies, Humans, Omeprazole therapeutic use, Penicillins therapeutic use, Peptic Ulcer Hemorrhage microbiology, Diverticulum microbiology, Duodenal Diseases microbiology, Duodenal Ulcer microbiology, Helicobacter Infections drug therapy, Helicobacter pylori, Peptic Ulcer Hemorrhage prevention & control
- Published
- 2000
- Full Text
- View/download PDF
88. [Efficacy of peristil treatment in primary and secondary duodenal dyskinesias].
- Author
-
Simanenkov VI and Lutaenko EA
- Subjects
- Adolescent, Adult, Female, Humans, Male, Middle Aged, Treatment Outcome, Anti-Ulcer Agents therapeutic use, Cisapride therapeutic use, Duodenal Diseases drug therapy, Duodenal Diseases physiopathology, Gastrointestinal Motility physiology
- Abstract
Clinical studies of peristil demonstrated that this drug is effective in hypomotor and dysmotor gastroduodenal disturbances leading to reduction of clinical symptoms of primary and secondary duodenodyskinesias. A systemic prokinetic action of peristil is beneficial in patients with duodenodiskinesia combination with gastroesophageal reflux as well as hypomotor constipation syndrome. Also, peristil reduces depressive symptoms and improves quality of life in patients with primary and secondary duodenodyskinesias.
- Published
- 2000
89. Clinical quiz. Mycobacterium avium-intracellurare.
- Author
-
Del Rosario MA
- Subjects
- Adolescent, Biopsy, Duodenal Diseases drug therapy, Duodenal Diseases pathology, Female, Humans, Macrophages microbiology, Mycobacterium avium Complex isolation & purification, Mycobacterium avium-intracellulare Infection complications, Mycobacterium avium-intracellulare Infection drug therapy, Duodenal Diseases microbiology, HIV Infections complications, Mycobacterium avium-intracellulare Infection diagnosis
- Published
- 1999
- Full Text
- View/download PDF
90. Schönlein-Henoch purpura with severe duodenal involvement treated with corticosteroids.
- Author
-
van Laar JA, Meijssen MA, Van't Veen A, Tjiong HL, and van Blankenstein M
- Subjects
- Dose-Response Relationship, Drug, Duodenal Diseases pathology, Duodenum pathology, Female, Humans, IgA Vasculitis pathology, Middle Aged, Prednisone administration & dosage, Duodenal Diseases drug therapy, Duodenoscopy, IgA Vasculitis drug therapy
- Published
- 1998
- Full Text
- View/download PDF
91. [Duodenal Crohn's disease: diagnostic and therapeutic complexity].
- Author
-
Sanjuán Portugal F, Cabrera Chaves T, Yus Gotor C, and Gomollón García F
- Subjects
- Adolescent, Anti-Inflammatory Agents therapeutic use, Azathioprine therapeutic use, Diagnosis, Differential, Female, Follow-Up Studies, Humans, Immunosuppressive Agents therapeutic use, Methylprednisolone therapeutic use, Time Factors, Crohn Disease diagnosis, Crohn Disease drug therapy, Duodenal Diseases diagnosis, Duodenal Diseases drug therapy
- Abstract
Crohn's disease may involve any area of the digestive tract, but its localization in the duodenum is rare. The clinical, radiological or endoscopic findings may simulate those of peptic ulcer and histologic examination is not diagnostic. In contrast with Crohn's disease of any other localization, the formation of fistulas is exceptional. The authors present one case of duodenal Crohn's disease the unspecific symptomatology of which deviated the original orientation towards the more common diseases. Steroid treatment was not sufficient to control the disease which led to complications with the formation of an enterocutaneous fistula. The association of azathioprine was very effective not only in achieving remission of the process, but also in resolving the complications.
- Published
- 1998
92. [Schistosoma haematobium in an infant: a duodenal infection].
- Author
-
Kalach N, Nocton F, Barhoum M, Debard A, de Mongolfier I, Bonnard P, Dupic L, Kazerouni F, Osman Z, and Benhamou PH
- Subjects
- Animals, Child, Duodenal Diseases diagnosis, Duodenal Diseases drug therapy, Humans, Male, Duodenal Diseases parasitology, Intestinal Diseases, Parasitic diagnosis, Intestinal Diseases, Parasitic drug therapy, Schistosomiasis haematobia diagnosis, Schistosomiasis haematobia drug therapy
- Published
- 1998
- Full Text
- View/download PDF
93. [Gastroduodenal diseases associated with helicobacter pylori].
- Author
-
Grigor'ev PIa and Iakovenko EP
- Subjects
- Anti-Bacterial Agents, Anti-Ulcer Agents administration & dosage, Anti-Ulcer Agents therapeutic use, Biopsy, Drug Administration Schedule, Drug Therapy, Combination administration & dosage, Drug Therapy, Combination therapeutic use, Duodenal Diseases diagnosis, Duodenal Diseases drug therapy, Endoscopy, Digestive System, Helicobacter pylori isolation & purification, Humans, Intestinal Mucosa microbiology, Peptic Ulcer diagnosis, Peptic Ulcer drug therapy, Peptic Ulcer microbiology, Stomach Diseases diagnosis, Stomach Diseases drug therapy, Duodenal Diseases microbiology, Helicobacter pylori pathogenicity, Stomach Diseases microbiology
- Published
- 1998
94. [Experimental evidence for pharmacotherapy of cardiovascular and gastroduodenal diseases induced by the body's extreme exposures].
- Author
-
Zavodskaia IS, Sapronov NS, Bul'on VV, and Khnychenko LK
- Subjects
- Cardiovascular Diseases etiology, Cardiovascular Diseases metabolism, Duodenal Diseases etiology, Duodenal Diseases metabolism, Humans, Neurotransmitter Agents metabolism, Stomach Diseases etiology, Stomach Diseases metabolism, Sympathetic Nervous System drug effects, Sympathetic Nervous System physiology, Treatment Outcome, Autonomic Agents therapeutic use, Cardiovascular Diseases drug therapy, Duodenal Diseases drug therapy, Stomach Diseases drug therapy, Stress, Psychological
- Abstract
The results of examining the mechanisms of development of neurogenic visceral abnormalities induced by the body's extreme exposures, search for modes of its pharmacological correction are presented. Experiments have provided evidence for that the neutropic agents recovering the functional activity of the sympathetic nervous system, normalizing energy and plastic exchange have a positive effect in the treatment of the cardiovascular and gastroduodenal diseases which are caused by a neurogenic agent. A basically new approach to treating peptic ulcer, coronary heart diseases, and myocardial infarction is proposed depending on the stage of a disease.
- Published
- 1998
95. Ménétrier's disease: a new variant with duodenal involvement.
- Author
-
Wu CS, Lin CJ, Chen TC, Chen PC, and Chiu CC
- Subjects
- Aged, Barium Sulfate, Contrast Media, Duodenal Diseases diagnostic imaging, Duodenal Diseases drug therapy, Famotidine therapeutic use, Gastric Fundus pathology, Gastric Mucosa pathology, Gastritis, Hypertrophic diagnostic imaging, Gastritis, Hypertrophic drug therapy, Gastroscopy, Histamine H2 Antagonists therapeutic use, Humans, Hyperplasia, Intestinal Mucosa pathology, Male, Metaplasia, Pylorus pathology, Radiography, Serum Albumin analysis, Stomach diagnostic imaging, Stomach pathology, Weight Loss, Duodenal Diseases pathology, Gastritis, Hypertrophic pathology
- Abstract
Ménétrier's disease is a rare cause of hypertrophic gastropathy, usually confined to gastric body and fundus, which is characterized by giant rugae, hypoalbuminemia, and foveolar hyperplasia. The etiology of this disease is still unknown. We report a case of a 74-yr-old man who had dyspepsia, hypoalbuminemia, weight loss, and diffuse polypoid, nodular lesions affecting the whole stomach and proximal duodenum on gastroscopy and barium meal study. The histology of gastric and duodenal mucosal lesions fulfilled the diagnosis of Ménétrier's disease, that was not described to involve duodenum in the literature. The disease resolved clinically, endoscopically, and pathologically after therapy with famotidine for 3 months. We speculated that extensive pyloric metaplasia and then foveolar hyperplasia of duodenum in this patient might be a variant of Ménétrier's disease with favorable clinical course.
- Published
- 1997
96. [Helicobacter pylori and gastroduodenal pathology: its pathogenesis, diagnosis and therapeutic guidelines].
- Author
-
Muñoz Gutiérrez J, Iglesias Franco H, and Fidalgo García L
- Subjects
- Anti-Bacterial Agents, Drug Therapy, Combination therapeutic use, Duodenal Diseases diagnosis, Duodenal Diseases drug therapy, Helicobacter Infections diagnosis, Helicobacter Infections drug therapy, Humans, Stomach Diseases diagnosis, Stomach Diseases drug therapy, Duodenal Diseases etiology, Helicobacter Infections etiology, Helicobacter pylori, Stomach Diseases etiology
- Published
- 1997
97. Two young Somalians with gastric outlet obstruction as a first manifestation of gastroduodenal tuberculosis.
- Author
-
Woudstra M, van Tilburg AJ, and Tjen JS
- Subjects
- Adult, Antitubercular Agents therapeutic use, DNA, Bacterial analysis, Duodenal Diseases diagnosis, Duodenal Diseases drug therapy, Endoscopy, Digestive System, Female, Gastric Outlet Obstruction diagnosis, Gastric Outlet Obstruction drug therapy, Humans, Intestinal Mucosa microbiology, Intestinal Mucosa pathology, Male, Mycobacterium tuberculosis genetics, Polymerase Chain Reaction, Somalia, Stomach Diseases diagnosis, Stomach Diseases drug therapy, Tuberculosis, Gastrointestinal diagnosis, Tuberculosis, Gastrointestinal drug therapy, Duodenal Diseases complications, Gastric Outlet Obstruction etiology, Stomach Diseases complications, Tuberculosis, Gastrointestinal complications
- Abstract
Gastroduodenal tuberculosis (GDTB) is an uncommon condition which can mimic other gastrointestinal disorders. It usually occurs secondary to pulmonary tuberculosis. We describe two young Somalian patients who presented with abdominal pain and gastric outlet obstruction. GDTB was diagnosed in both patients and they were successfully treated with antituberculous drugs.
- Published
- 1997
- Full Text
- View/download PDF
98. [Useful treatment modality for postoperative duodenal fistula with somatostatin analogue].
- Author
-
Kikuchi M, Endo S, Kuwata Y, and Kasai T
- Subjects
- Accidents, Traffic, Adult, Duodenal Diseases etiology, Humans, Intestinal Fistula etiology, Male, Pancreas injuries, Somatostatin therapeutic use, Duodenal Diseases drug therapy, Duodenum injuries, Duodenum surgery, Intestinal Fistula drug therapy, Postoperative Complications drug therapy, Somatostatin analogs & derivatives
- Abstract
A case with leakage of duodenal stump treated by a somatostatin analogue (SMS 201-995,SMS) effectively was reported. A 39-year-old man had underwent gastric resection (Billroth I) and distal pancreaticojejunostomy for transsection of duodenal bulbus and pancreatic body. After 14 days later duodenal diverticulization was performed due to anastomotic stricture of the gastro-duodenostomy, which resulted in leakage of duodenal stump and voluminous fluids from drains were lasting about 5 weeks. Amylase (AMY) value was shown as high as 703,812 U/l in the exudate. SMS was injected by 100 micrograms, s, c, by three times a day for 24 days. The volume of exudate decreased immediately after the administration of SMS and to one-half in volume in 2 weeks. AMY also fell to 42, 378 U/l. The drain was removed two months after the third surgery. The patient was discharged on post operative day 200. SMS was known to inhibit secretion of bile and intestinal as well as pancreatic juice and its usefulness for leakage of the intestinal tract, especially of the duodenum, is suggested.
- Published
- 1997
99. Pancreaticoduodenal tuberculosis simulating metastatic ovarian carcinoma.
- Author
-
Zalev AH, Sacks JS, and Warren RE
- Subjects
- Adenofibroma physiopathology, Adenofibroma surgery, Adult, Antitubercular Agents administration & dosage, Antitubercular Agents therapeutic use, Biopsy, Diagnosis, Differential, Duodenal Diseases drug therapy, Duodenal Diseases physiopathology, Female, Humans, Laparotomy, Ovarian Neoplasms physiopathology, Ovarian Neoplasms secondary, Ovarian Neoplasms surgery, Pancreatic Diseases drug therapy, Pancreatic Diseases physiopathology, Tomography, X-Ray Computed, Tuberculosis, Gastrointestinal drug therapy, Tuberculosis, Gastrointestinal physiopathology, Adenofibroma diagnosis, Duodenal Diseases diagnosis, Ovarian Neoplasms diagnosis, Pancreatic Diseases diagnosis, Tuberculosis, Gastrointestinal diagnosis
- Abstract
A patient from Thailand presented with symptoms suggestive of peptic ulceration. Radiology showed an ulcerated duodenal stricture, a pancreaticoduodenal mass and extensive retroperitoneal lymphadenopathy suggestive of metastatic carcinoma. Tuberculosis was diagnosed only at laparotomy. The incidence of tuberculosis is increasing, and alimentary tuberculosis should be considered in patients from populations at risk presenting with obscure abdominal complaints or unexplained radiologic findings.
- Published
- 1997
- Full Text
- View/download PDF
100. Duodenal and hepatic toxoplasmosis in a patient with HIV infection: review of the literature.
- Author
-
Bonacini M, Kanel G, and Alamy M
- Subjects
- AIDS-Related Opportunistic Infections drug therapy, AIDS-Related Opportunistic Infections parasitology, Adult, Anti-Infective Agents therapeutic use, Clindamycin therapeutic use, Diarrhea parasitology, Duodenal Diseases drug therapy, Humans, Intestinal Diseases, Parasitic drug therapy, Leucovorin therapeutic use, Liver Diseases, Parasitic drug therapy, Male, Prevalence, Pyrimethamine therapeutic use, Toxoplasmosis drug therapy, AIDS-Related Opportunistic Infections epidemiology, Duodenal Diseases parasitology, Intestinal Diseases, Parasitic epidemiology, Liver Diseases, Parasitic epidemiology, Toxoplasmosis epidemiology
- Abstract
We report a case of watery diarrhea due to duodenal toxoplasmosis in a patient with the acquired immunodeficiency syndrome. Treatment with pyrimethamine, clindamycin, and folinic acid decreased the diarrhea as well as the duodenal toxoplasma cyst load. Hepatic toxoplasmosis was also present, associated with an elevated serum alkaline phosphatase activity and a minimally elevated lactate dehydrogenase level.
- Published
- 1996
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.