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1,236 results on '"Fiorentino, Michelangelo"'

52. An Apparent Diffusion Coefficient-Based Machine Learning Model Can Improve Prostate Cancer Detection in the Grey Area of the Prostate Imaging Reporting and Data System Category 3: A Single-Centre Experience

Author

Gaudiano, Caterina, primary, Mottola, Margherita, additional, Bianchi, Lorenzo, additional, Corcioni, Beniamino, additional, Braccischi, Lorenzo, additional, Tomassoni, Makoto Taninokuchi, additional, Cattabriga, Arrigo, additional, Cocozza, Maria Adriana, additional, Giunchi, Francesca, additional, Schiavina, Riccardo, additional, Fanti, Stefano, additional, Fiorentino, Michelangelo, additional, Brunocilla, Eugenio, additional, Mosconi, Cristina, additional, and Bevilacqua, Alessandro, additional

Published
2023
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53. Multi-Gene Next-Generation Sequencing Panel for Analysis of BRCA1/BRCA2 and Homologous Recombination Repair Genes Alterations Metastatic Castration-Resistant Prostate Cancer

Author

Maloberti, Thais, primary, De Leo, Antonio, additional, Coluccelli, Sara, additional, Sanza, Viviana, additional, Gruppioni, Elisa, additional, Altimari, Annalisa, additional, Zagnoni, Stefano, additional, Giunchi, Francesca, additional, Vasuri, Francesco, additional, Fiorentino, Michelangelo, additional, Mollica, Veronica, additional, Ferrari, Simona, additional, Miccoli, Sara, additional, Visani, Michela, additional, Turchetti, Daniela, additional, Massari, Francesco, additional, Tallini, Giovanni, additional, and de Biase, Dario, additional

Published
2023
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54. Supplementary Figure from AXL and Error-Prone DNA Replication Confer Drug Resistance and Offer Strategies to Treat EGFR-Mutant Lung Cancer

Author

Noronha, Ashish, primary, Belugali Nataraj, Nishanth, primary, Lee, Joo Sang, primary, Zhitomirsky, Benny, primary, Oren, Yaara, primary, Oster, Sara, primary, Lindzen, Moshit, primary, Mukherjee, Saptaparna, primary, Will, Rainer, primary, Ghosh, Soma, primary, Simoni-Nieves, Arturo, primary, Verma, Aakanksha, primary, Chatterjee, Rishita, primary, Borgoni, Simone, primary, Robinson, Welles, primary, Sinha, Sanju, primary, Brandis, Alexander, primary, Kerr, D. Lucas, primary, Wu, Wei, primary, Sekar, Arunachalam, primary, Giri, Suvendu, primary, Chung, Youngmin, primary, Drago-Garcia, Diana, primary, Danysh, Brian P., primary, Lauriola, Mattia, primary, Fiorentino, Michelangelo, primary, Ardizzoni, Andrea, primary, Oren, Moshe, primary, Blakely, Collin M., primary, Ezike, Jideofor, primary, Wiemann, Stefan, primary, Parida, Laxmi, primary, Bivona, Trever G., primary, Aqeilan, Rami I., primary, Brugge, Joan S., primary, Regev, Aviv, primary, Getz, Gad, primary, Ruppin, Eytan, primary, and Yarden, Yosef, primary

Published
2023
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55. Data from AXL and Error-Prone DNA Replication Confer Drug Resistance and Offer Strategies to Treat EGFR-Mutant Lung Cancer

Author

Noronha, Ashish, primary, Belugali Nataraj, Nishanth, primary, Lee, Joo Sang, primary, Zhitomirsky, Benny, primary, Oren, Yaara, primary, Oster, Sara, primary, Lindzen, Moshit, primary, Mukherjee, Saptaparna, primary, Will, Rainer, primary, Ghosh, Soma, primary, Simoni-Nieves, Arturo, primary, Verma, Aakanksha, primary, Chatterjee, Rishita, primary, Borgoni, Simone, primary, Robinson, Welles, primary, Sinha, Sanju, primary, Brandis, Alexander, primary, Kerr, D. Lucas, primary, Wu, Wei, primary, Sekar, Arunachalam, primary, Giri, Suvendu, primary, Chung, Youngmin, primary, Drago-Garcia, Diana, primary, Danysh, Brian P., primary, Lauriola, Mattia, primary, Fiorentino, Michelangelo, primary, Ardizzoni, Andrea, primary, Oren, Moshe, primary, Blakely, Collin M., primary, Ezike, Jideofor, primary, Wiemann, Stefan, primary, Parida, Laxmi, primary, Bivona, Trever G., primary, Aqeilan, Rami I., primary, Brugge, Joan S., primary, Regev, Aviv, primary, Getz, Gad, primary, Ruppin, Eytan, primary, and Yarden, Yosef, primary

Published
2023
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56. Abstract 737: Variation in prognostic value of Gleason score for lethal prostate cancer using time-varying area under the curve

Author

Lin, Zhike, primary, Stopsack, Konrad H., additional, Fiorentino, Michelangelo, additional, Vaselkiv, Jane B., additional, Gerke, Travis, additional, Pettersson, Andreas, additional, Flanagan, Sinead, additional, Penney, Kathryn L., additional, Finn, Stephen P., additional, Loda, Massimo, additional, and Mucci, Lorelei A., additional

Published
2023
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57. Supplementary Data from AXL and Error-Prone DNA Replication Confer Drug Resistance and Offer Strategies to Treat EGFR-Mutant Lung Cancer

Author

Noronha, Ashish, primary, Belugali Nataraj, Nishanth, primary, Lee, Joo Sang, primary, Zhitomirsky, Benny, primary, Oren, Yaara, primary, Oster, Sara, primary, Lindzen, Moshit, primary, Mukherjee, Saptaparna, primary, Will, Rainer, primary, Ghosh, Soma, primary, Simoni-Nieves, Arturo, primary, Verma, Aakanksha, primary, Chatterjee, Rishita, primary, Borgoni, Simone, primary, Robinson, Welles, primary, Sinha, Sanju, primary, Brandis, Alexander, primary, Kerr, D. Lucas, primary, Wu, Wei, primary, Sekar, Arunachalam, primary, Giri, Suvendu, primary, Chung, Youngmin, primary, Drago-Garcia, Diana, primary, Danysh, Brian P., primary, Lauriola, Mattia, primary, Fiorentino, Michelangelo, primary, Ardizzoni, Andrea, primary, Oren, Moshe, primary, Blakely, Collin M., primary, Ezike, Jideofor, primary, Wiemann, Stefan, primary, Parida, Laxmi, primary, Bivona, Trever G., primary, Aqeilan, Rami I., primary, Brugge, Joan S., primary, Regev, Aviv, primary, Getz, Gad, primary, Ruppin, Eytan, primary, and Yarden, Yosef, primary

Published
2023
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59. Supplementary Figure 1 from Metabolomics of Prostate Cancer Gleason Score in Tumor Tissue and Serum

Author

Penney, Kathryn L., primary, Tyekucheva, Svitlana, primary, Rosenthal, Jacob, primary, El Fandy, Habiba, primary, Carelli, Ryan, primary, Borgstein, Stephanie, primary, Zadra, Giorgia, primary, Fanelli, Giuseppe Nicolò, primary, Stefanizzi, Lavinia, primary, Giunchi, Francesca, primary, Pomerantz, Mark, primary, Peisch, Samuel, primary, Coulson, Hannah, primary, Lis, Rosina, primary, Kibel, Adam S., primary, Fiorentino, Michelangelo, primary, Umeton, Renato, primary, and Loda, Massimo, primary

Published
2023
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60. Supplementary Figure 4 from Metabolomics of Prostate Cancer Gleason Score in Tumor Tissue and Serum

Author

Penney, Kathryn L., primary, Tyekucheva, Svitlana, primary, Rosenthal, Jacob, primary, El Fandy, Habiba, primary, Carelli, Ryan, primary, Borgstein, Stephanie, primary, Zadra, Giorgia, primary, Fanelli, Giuseppe Nicolò, primary, Stefanizzi, Lavinia, primary, Giunchi, Francesca, primary, Pomerantz, Mark, primary, Peisch, Samuel, primary, Coulson, Hannah, primary, Lis, Rosina, primary, Kibel, Adam S., primary, Fiorentino, Michelangelo, primary, Umeton, Renato, primary, and Loda, Massimo, primary

Published
2023
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62. Supplementary Figure 2 from Metabolomics of Prostate Cancer Gleason Score in Tumor Tissue and Serum

Author

Penney, Kathryn L., primary, Tyekucheva, Svitlana, primary, Rosenthal, Jacob, primary, El Fandy, Habiba, primary, Carelli, Ryan, primary, Borgstein, Stephanie, primary, Zadra, Giorgia, primary, Fanelli, Giuseppe Nicolò, primary, Stefanizzi, Lavinia, primary, Giunchi, Francesca, primary, Pomerantz, Mark, primary, Peisch, Samuel, primary, Coulson, Hannah, primary, Lis, Rosina, primary, Kibel, Adam S., primary, Fiorentino, Michelangelo, primary, Umeton, Renato, primary, and Loda, Massimo, primary

Published
2023
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64. Supplementary Figure 3 from Metabolomics of Prostate Cancer Gleason Score in Tumor Tissue and Serum

Author

Penney, Kathryn L., primary, Tyekucheva, Svitlana, primary, Rosenthal, Jacob, primary, El Fandy, Habiba, primary, Carelli, Ryan, primary, Borgstein, Stephanie, primary, Zadra, Giorgia, primary, Fanelli, Giuseppe Nicolò, primary, Stefanizzi, Lavinia, primary, Giunchi, Francesca, primary, Pomerantz, Mark, primary, Peisch, Samuel, primary, Coulson, Hannah, primary, Lis, Rosina, primary, Kibel, Adam S., primary, Fiorentino, Michelangelo, primary, Umeton, Renato, primary, and Loda, Massimo, primary

Published
2023
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66. Supplementary Tables 1-5, Supplementary Figures 1-3 from Transcriptomes of Prostate Cancer with TMPRSS2:ERG and Other ETS Fusions

Author

Stopsack, Konrad H., primary, Su, Xiaofeng A., primary, Vaselkiv, J. Bailey, primary, Graff, Rebecca E., primary, Ebot, Ericka M., primary, Pettersson, Andreas, primary, Lis, Rosina T., primary, Fiorentino, Michelangelo, primary, Loda, Massimo, primary, Penney, Kathryn L., primary, Lotan, Tamara L., primary, and Mucci, Lorelei A., primary

Published
2023
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67. Supplementary Data from Metabolomics of Prostate Cancer Gleason Score in Tumor Tissue and Serum

Author

Penney, Kathryn L., primary, Tyekucheva, Svitlana, primary, Rosenthal, Jacob, primary, El Fandy, Habiba, primary, Carelli, Ryan, primary, Borgstein, Stephanie, primary, Zadra, Giorgia, primary, Fanelli, Giuseppe Nicolò, primary, Stefanizzi, Lavinia, primary, Giunchi, Francesca, primary, Pomerantz, Mark, primary, Peisch, Samuel, primary, Coulson, Hannah, primary, Lis, Rosina, primary, Kibel, Adam S., primary, Fiorentino, Michelangelo, primary, Umeton, Renato, primary, and Loda, Massimo, primary

Published
2023
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68. Data from Metabolomics of Prostate Cancer Gleason Score in Tumor Tissue and Serum

Author

Penney, Kathryn L., primary, Tyekucheva, Svitlana, primary, Rosenthal, Jacob, primary, El Fandy, Habiba, primary, Carelli, Ryan, primary, Borgstein, Stephanie, primary, Zadra, Giorgia, primary, Fanelli, Giuseppe Nicolò, primary, Stefanizzi, Lavinia, primary, Giunchi, Francesca, primary, Pomerantz, Mark, primary, Peisch, Samuel, primary, Coulson, Hannah, primary, Lis, Rosina, primary, Kibel, Adam S., primary, Fiorentino, Michelangelo, primary, Umeton, Renato, primary, and Loda, Massimo, primary

Published
2023
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69. Supplementary Table 1 from Metabolomics of Prostate Cancer Gleason Score in Tumor Tissue and Serum

Author

Penney, Kathryn L., primary, Tyekucheva, Svitlana, primary, Rosenthal, Jacob, primary, El Fandy, Habiba, primary, Carelli, Ryan, primary, Borgstein, Stephanie, primary, Zadra, Giorgia, primary, Fanelli, Giuseppe Nicolò, primary, Stefanizzi, Lavinia, primary, Giunchi, Francesca, primary, Pomerantz, Mark, primary, Peisch, Samuel, primary, Coulson, Hannah, primary, Lis, Rosina, primary, Kibel, Adam S., primary, Fiorentino, Michelangelo, primary, Umeton, Renato, primary, and Loda, Massimo, primary

Published
2023
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72. The Tumor Entity Denominated “clear cell-papillary renal cell carcinoma” According to the WHO 2016 new Classification, have the Clinical Characters of a Renal Cell Adenoma as does Harbor a Benign Outcome

Author

Massari, Francesco, Ciccarese, Chiara, Hes, Ondrej, Michal, Michal, Caliò, Anna, Fiorentino, Michelangelo, Giunchi, Francesca, D’Amuri, Alessandro, Sanguedolce, Francesca, Sabbatini, Roberto, Guida, Annalisa, Ardizzoni, Andrea, Porta, Camillo, Iacovelli, Roberto, Tortora, Giampaolo, Cima, Luca, Ortega, Cinzia, Lapini, Alberto, Martignoni, Guido, and Brunelli, Matteo

Published
2018
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75. Supplementary Table 4 from Common Polymorphisms in the Adiponectin and Its Receptor Genes, Adiponectin Levels and the Risk of Prostate Cancer

Author

Dhillon, Preet K., primary, Penney, Kathryn L., primary, Schumacher, Fredrick, primary, Rider, Jennifer R., primary, Sesso, Howard D., primary, Pollak, Michael, primary, Fiorentino, Michelangelo, primary, Finn, Stephen, primary, Loda, Massimo, primary, Rifai, Nader, primary, Mucci, Lorelei A., primary, Giovannucci, Edward, primary, Stampfer, Meir J., primary, and Ma, Jing, primary

Published
2023
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76. Supplementary Figure 1 from The TMPRSS2:ERG Rearrangement, ERG Expression, and Prostate Cancer Outcomes: A Cohort Study and Meta-analysis

Author

Pettersson, Andreas, primary, Graff, Rebecca E., primary, Bauer, Scott R., primary, Pitt, Michael J., primary, Lis, Rosina T., primary, Stack, Edward C., primary, Martin, Neil E., primary, Kunz, Lauren, primary, Penney, Kathryn L., primary, Ligon, Azra H., primary, Suppan, Catherine, primary, Flavin, Richard, primary, Sesso, Howard D., primary, Rider, Jennifer R., primary, Sweeney, Christopher, primary, Stampfer, Meir J., primary, Fiorentino, Michelangelo, primary, Kantoff, Philip W., primary, Sanda, Martin G., primary, Giovannucci, Edward L., primary, Ding, Eric L., primary, Loda, Massimo, primary, and Mucci, Lorelei A., primary

Published
2023
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78. Supplementary Table 3 from The TMPRSS2:ERG Rearrangement, ERG Expression, and Prostate Cancer Outcomes: A Cohort Study and Meta-analysis

Author

Pettersson, Andreas, primary, Graff, Rebecca E., primary, Bauer, Scott R., primary, Pitt, Michael J., primary, Lis, Rosina T., primary, Stack, Edward C., primary, Martin, Neil E., primary, Kunz, Lauren, primary, Penney, Kathryn L., primary, Ligon, Azra H., primary, Suppan, Catherine, primary, Flavin, Richard, primary, Sesso, Howard D., primary, Rider, Jennifer R., primary, Sweeney, Christopher, primary, Stampfer, Meir J., primary, Fiorentino, Michelangelo, primary, Kantoff, Philip W., primary, Sanda, Martin G., primary, Giovannucci, Edward L., primary, Ding, Eric L., primary, Loda, Massimo, primary, and Mucci, Lorelei A., primary

Published
2023
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79. Supplementary Table 3 from Common Polymorphisms in the Adiponectin and Its Receptor Genes, Adiponectin Levels and the Risk of Prostate Cancer

Author

Dhillon, Preet K., primary, Penney, Kathryn L., primary, Schumacher, Fredrick, primary, Rider, Jennifer R., primary, Sesso, Howard D., primary, Pollak, Michael, primary, Fiorentino, Michelangelo, primary, Finn, Stephen, primary, Loda, Massimo, primary, Rifai, Nader, primary, Mucci, Lorelei A., primary, Giovannucci, Edward, primary, Stampfer, Meir J., primary, and Ma, Jing, primary

Published
2023
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80. Data from Stress-Related Signaling Pathways in Lethal and Nonlethal Prostate Cancer

Author

Lu, Donghao, primary, Sinnott, Jennifer A., primary, Valdimarsdóttir, Unnur, primary, Fang, Fang, primary, Gerke, Travis, primary, Tyekucheva, Svitlana, primary, Fiorentino, Michelangelo, primary, Lambe, Mats, primary, Sesso, Howard D., primary, Sweeney, Christopher J., primary, Wilson, Kathryn M., primary, Giovannucci, Edward L., primary, Loda, Massimo, primary, Mucci, Lorelei A., primary, and Fall, Katja, primary

Published
2023
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81. Supplementary Table 1 from Common Polymorphisms in the Adiponectin and Its Receptor Genes, Adiponectin Levels and the Risk of Prostate Cancer

Author

Dhillon, Preet K., primary, Penney, Kathryn L., primary, Schumacher, Fredrick, primary, Rider, Jennifer R., primary, Sesso, Howard D., primary, Pollak, Michael, primary, Fiorentino, Michelangelo, primary, Finn, Stephen, primary, Loda, Massimo, primary, Rifai, Nader, primary, Mucci, Lorelei A., primary, Giovannucci, Edward, primary, Stampfer, Meir J., primary, and Ma, Jing, primary

Published
2023
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82. Data from The TMPRSS2:ERG Rearrangement, ERG Expression, and Prostate Cancer Outcomes: A Cohort Study and Meta-analysis

Author

Pettersson, Andreas, primary, Graff, Rebecca E., primary, Bauer, Scott R., primary, Pitt, Michael J., primary, Lis, Rosina T., primary, Stack, Edward C., primary, Martin, Neil E., primary, Kunz, Lauren, primary, Penney, Kathryn L., primary, Ligon, Azra H., primary, Suppan, Catherine, primary, Flavin, Richard, primary, Sesso, Howard D., primary, Rider, Jennifer R., primary, Sweeney, Christopher, primary, Stampfer, Meir J., primary, Fiorentino, Michelangelo, primary, Kantoff, Philip W., primary, Sanda, Martin G., primary, Giovannucci, Edward L., primary, Ding, Eric L., primary, Loda, Massimo, primary, and Mucci, Lorelei A., primary

Published
2023
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84. Supplementary Figure 1 from Common Polymorphisms in the Adiponectin and Its Receptor Genes, Adiponectin Levels and the Risk of Prostate Cancer

Author

Dhillon, Preet K., primary, Penney, Kathryn L., primary, Schumacher, Fredrick, primary, Rider, Jennifer R., primary, Sesso, Howard D., primary, Pollak, Michael, primary, Fiorentino, Michelangelo, primary, Finn, Stephen, primary, Loda, Massimo, primary, Rifai, Nader, primary, Mucci, Lorelei A., primary, Giovannucci, Edward, primary, Stampfer, Meir J., primary, and Ma, Jing, primary

Published
2023
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85. Supplementary Table 2 from Common Polymorphisms in the Adiponectin and Its Receptor Genes, Adiponectin Levels and the Risk of Prostate Cancer

Author

Dhillon, Preet K., primary, Penney, Kathryn L., primary, Schumacher, Fredrick, primary, Rider, Jennifer R., primary, Sesso, Howard D., primary, Pollak, Michael, primary, Fiorentino, Michelangelo, primary, Finn, Stephen, primary, Loda, Massimo, primary, Rifai, Nader, primary, Mucci, Lorelei A., primary, Giovannucci, Edward, primary, Stampfer, Meir J., primary, and Ma, Jing, primary

Published
2023
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86. Supplementary Tables 1, 2, 4 and 5 from The TMPRSS2:ERG Rearrangement, ERG Expression, and Prostate Cancer Outcomes: A Cohort Study and Meta-analysis

Author

Pettersson, Andreas, primary, Graff, Rebecca E., primary, Bauer, Scott R., primary, Pitt, Michael J., primary, Lis, Rosina T., primary, Stack, Edward C., primary, Martin, Neil E., primary, Kunz, Lauren, primary, Penney, Kathryn L., primary, Ligon, Azra H., primary, Suppan, Catherine, primary, Flavin, Richard, primary, Sesso, Howard D., primary, Rider, Jennifer R., primary, Sweeney, Christopher, primary, Stampfer, Meir J., primary, Fiorentino, Michelangelo, primary, Kantoff, Philip W., primary, Sanda, Martin G., primary, Giovannucci, Edward L., primary, Ding, Eric L., primary, Loda, Massimo, primary, and Mucci, Lorelei A., primary

Published
2023
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87. Data from Common Polymorphisms in the Adiponectin and Its Receptor Genes, Adiponectin Levels and the Risk of Prostate Cancer

Author

Dhillon, Preet K., primary, Penney, Kathryn L., primary, Schumacher, Fredrick, primary, Rider, Jennifer R., primary, Sesso, Howard D., primary, Pollak, Michael, primary, Fiorentino, Michelangelo, primary, Finn, Stephen, primary, Loda, Massimo, primary, Rifai, Nader, primary, Mucci, Lorelei A., primary, Giovannucci, Edward, primary, Stampfer, Meir J., primary, and Ma, Jing, primary

Published
2023
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88. Supplementary Table S1 from Stress-Related Signaling Pathways in Lethal and Nonlethal Prostate Cancer

Author

Lu, Donghao, primary, Sinnott, Jennifer A., primary, Valdimarsdóttir, Unnur, primary, Fang, Fang, primary, Gerke, Travis, primary, Tyekucheva, Svitlana, primary, Fiorentino, Michelangelo, primary, Lambe, Mats, primary, Sesso, Howard D., primary, Sweeney, Christopher J., primary, Wilson, Kathryn M., primary, Giovannucci, Edward L., primary, Loda, Massimo, primary, Mucci, Lorelei A., primary, and Fall, Katja, primary

Published
2023
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93. Transverse prostate maximum sectional area can predict clinically significant prostate cancer in PI-RADS 3 lesions at multiparametric magnetic resonance imaging

Author

Gaudiano, Caterina, primary, Braccischi, Lorenzo, additional, Taninokuchi Tomassoni, Makoto, additional, Paccapelo, Alexandro, additional, Bianchi, Lorenzo, additional, Corcioni, Beniamino, additional, Ciccarese, Federica, additional, Schiavina, Riccardo, additional, Droghetti, Matteo, additional, Giunchi, Francesca, additional, Fiorentino, Michelangelo, additional, Brunocilla, Eugenio, additional, and Golfieri, Rita, additional

Published
2023
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94. Yolk sac tumor of postpubertal-type does not exhibit immunohistochemical loss of SMARCB1/INI1 and SMARCA4/BRG1…but choriocarcinoma?

Author

Ricci, Costantino, primary, Ambrosi, Francesca, additional, Franceschini, Tania, additional, Giunchi, Francesca, additional, Franchini, Eugenia, additional, Massari, Francesco, additional, Mollica, Veronica, additional, Bianchi, Federico Mineo, additional, Colecchia, Maurizio, additional, Acosta, Andres Martin, additional, and Fiorentino, Michelangelo, additional

Published
2023
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99. FoxA2 is a reliable marker for the diagnosis of yolk sac tumour postpubertal‐type.

Author

Ricci, Costantino, Ambrosi, Francesca, Franceschini, Tania, Giunchi, Francesca, Di Filippo, Giorgia, Franchini, Eugenia, Massari, Francesco, Mollica, Veronica, Tateo, Valentina, Bianchi, Federico Mineo, Colecchia, Maurizio, Acosta, Andres Martin, and Fiorentino, Michelangelo

Subjects
FORKHEAD transcription factors, GERM cells
Abstract

Aims: Yolk sac tumour postpubertal‐type (YSTpt) shows a wide range of histological patterns and is challenging to diagnose. Recently, forkhead box transcription factor A2 (FoxA2) emerged as a driver of YSTpt formation and a promising marker for diagnosing YSTpt. However, FoxA2 has not been tested in the different patterns of YSTpt. This study aimed to assess the staining pattern of FoxA2 in te different patterns of YSTpt and other germ cell tumours of the testis (GCTT), comparing it with glypican‐3 (GPC3) and α‐fetoprotein (AFP). Methods and results: FOXA2, GPC3 and AFP immunohistochemistry was performed on 24 YSTpt (24 microcystic/reticular, 10 myxoid, two macrocystic, five glandular/alveolar, two endodermal sinus/perivascular, four solid, two polyembryoma/embryoid body and two polyvesicular vitelline) and 81 other GCTT. The percentage of positive cells (0, 1+, 2+, 3+) and the intensity (0, 1, 2, 3) were evaluated regardless of and within each YSTpt pattern. FoxA2 was positive in all YSTpt (24 of 24) and all but one (23 of 24) exhibited 2+/3+ stain, with higher intensity [median value (mv): 2.6] than AFP (1.8) and GPC3 (2.5). Both FoxA2 and GPC3 were positive in all microcystic/reticular (24 of 24), myxoid (10 of 10), macrocystic (two of two), endodermal sinus/perivascular (four of four) and polyembryoma/embryoid body (two of two) patterns. Nevertheless, only FoxA2 was positive in all glandular/alveolar (five of five), solid (four of four) and polyvesicular vitelline (two of two) patterns. The intensity of FoxA2 was higher than AFP and GPC3 in almost all YST patterns. In the other GCTT, FoxA2 was positive only in teratoma postpubertal‐type (Tpt) [13 of 20 (65%)], with staining almost exclusively confined to the mature gastrointestinal/respiratory tract epithelium. Conclusions: FoxA2 is a highly sensitive and specific biomarker that supports the diagnosis of YSTpt. FoxA2 is superior to GPC3 and AFP, especially in rare and difficult‐to‐diagnose histological patterns of YSTpt, but mature glands of Tpt could represent a potential diagnostic pitfall. [ABSTRACT FROM AUTHOR]

Published
2023
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