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59 results on '"Goergen, Helen"'

51. Gonadal Function in Survivors After Hodgkin Lymphoma (HL) Treatment within the German Hodgkin Study Group (GHSG) HD13–15 Trials.

Author

Behringer, Karolin, primary, Mueller, Horst, additional, Goergen, Helen, additional, Thielen, Indra, additional, Eibl, Angelika, additional, Stumpf, Volker, additional, Wessels, Carsten, additional, Wiehlpuetz, Martin, additional, Rosenbrock, Johannes, additional, Halbsguth, Teresa, additional, Reiners, Katrin S., additional, Schober, Thomas, additional, Renno, Joerg H, additional, von Wolff, Michael, additional, van der Ven, Katrin, additional, Kuehr, Marietta, additional, Fuchs, Michael, additional, Diehl, Volker, additional, Engert, Andreas, additional, and Borchmann, Peter, additional

Published
2012
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53. Fertility and Gonadal Function After Treatment of Early Unfavorable Hodgkin Lymphoma (HL): An Analysis of the German Hodgkin Study Group (GHSG)

Author

Behringer, Karolin, primary, Thielen, Indra, additional, Mueller, Horst, additional, Goergen, Helen, additional, Eibl, Angelika, additional, Rosenbrock, Johannes, additional, Halbsguth, Teresa, additional, Reiners, Katrin S., additional, Diehl, Volker, additional, Engert, Andreas, additional, and Borchmann, Peter, additional

Published
2011
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54. Combined Modality Treatment with Intensified Chemotherapy and Dose-Reduced Involved Field Radiotherapy in Patients with Early Unfavourable Hodgkin Lymphoma (HL): Final Analysis of the German Hodgkin Study Group (GHSG) HD11 Trial.

Author

Borchmann, Peter, primary, Diehl, Volker, additional, Goergen, Helen, additional, Mueller, Horst, additional, Mueller, Rolf Peter, additional, Eich, Hans T., additional, Mueller-Hermelink, Hans Konrad, additional, Herrmann, Richard, additional, Markova, Jana, additional, Ho, Anthony D., additional, Hiddemann, Wolfgang, additional, Doerken, Bernd, additional, Greil, Richard, additional, and Engert, Andreas, additional

Published
2009
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58. PET-guided Treatment in Patients with Advanced-stage Hodgkin's Lymphoma (HD18): Final Results of An Open-label, International, Randomised Phase 3 Trial by the German Hodgkin Study Group.

Author

Borchmann, Peter, Goergen, Helen, Kobe, Carsten, Lohri, Andreas, Greil, Richard, Eichenauer, Dennis A., Zijlstra, Josée M., Markova, Jana, Meissner, Julia, Feuring-Buske, Michaela, Hüttmann, Andreas, Dierlamm, Judith, Soekler, Martin, Beck, Hans-Joachim, Willenbacher, Wolfgang, Ludwig, Wolf-Dieter, Pabst, Thomas, Topp, Max S., Hitz, Felicitas, and Bentz, Martin

Published
2018

59. Brentuximab vedotin for relapsed or refractory CD30+hematologic malignancies: the German Hodgkin Study Group experience

Author

Rothe, Achim, Sasse, Stephanie, Goergen, Helen, Eichenauer, Dennis A., Lohri, Andreas, Jäger, Ulrich, Bangard, Christopher, Böll, Boris, von Bergwelt Baildon, Michael, Theurich, Sebastian, Borchmann, Peter, and Engert, Andreas

Abstract

The CD30-targeting Ab-drug conjugate brentuximab vedotin (SGN-35) was recently approved for the treatment of relapsed Hodgkin lymphoma and anaplastic large-cell lymphoma by the Food and Drug Administration. In the present study, we report the experience of the German Hodgkin Study Group with brentuximab vedotin as single agent in 45 patients with refractory or relapsed CD30+Hodgkin lymphoma who were treated either in a named patient program (n = 34) or in the context of a safety study associated with the registration program of this drug. In these very heavily pretreated patients, an objective response rate of 60%, including 22% complete remissions, could be documented. The median duration of response was 8 months. This retrospective analysis supports the previously reported excellent therapeutic efficacy of brentuximab vedotin in heavily pretreated CD30+malignancies. This trial was registered at www.clinicaltrials.govwith identifier NCT01026233.

Published
2012
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