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51. Executive Summary

Author

Mozaffarian, Dariush, Benjamin, Emelia J, Go, Alan S, Arnett, Donna K, Blaha, Michael J, Cushman, Mary, Das, Sandeep R, de Ferranti, Sarah, Després, Jean-Pierre, Fullerton, Heather J, Howard, Virginia J, Huffman, Mark D, Isasi, Carmen R, Jiménez, Monik C, Judd, Suzanne E, Kissela, Brett M, Lichtman, Judith H, Lisabeth, Lynda D, Liu, Simin, Mackey, Rachel H, Magid, David J, McGuire, Darren K, Mohler, Emile R, Moy, Claudia S, Muntner, Paul, Mussolino, Michael E, Nasir, Khurram, Neumar, Robert W, Nichol, Graham, Palaniappan, Latha, Pandey, Dilip K, Reeves, Mathew J, Rodriguez, Carlos J, Rosamond, Wayne, Sorlie, Paul D, Stein, Joel, Towfighi, Amytis, Turan, Tanya N, Virani, Salim S, Woo, Daniel, Yeh, Robert W, and Turner, Melanie B

Subjects
Biomedical and Clinical Sciences, Cardiovascular Medicine and Haematology, Health Sciences, Clinical Sciences, Sports Science and Exercise, American Heart Association, Data Interpretation, Statistical, Health Behavior, Heart Diseases, Humans, Research Report, Stroke, United States, AHA Scientific Statements, cardiovascular diseases, epidemiology, risk factors, statistics, stroke, Writing Group Members, American Heart Association Statistics Committee, Stroke Statistics Subcommittee, Cardiorespiratory Medicine and Haematology, Public Health and Health Services, Cardiovascular System & Hematology, Cardiovascular medicine and haematology, Clinical sciences, Sports science and exercise
Published
2016

52. Executive Summary: Heart Disease and Stroke Statistics--2016 Update: A Report From the American Heart Association.

Author

Writing Group Members, Mozaffarian, Dariush, Benjamin, Emelia J, Go, Alan S, Arnett, Donna K, Blaha, Michael J, Cushman, Mary, Das, Sandeep R, de Ferranti, Sarah, Després, Jean-Pierre, Fullerton, Heather J, Howard, Virginia J, Huffman, Mark D, Isasi, Carmen R, Jiménez, Monik C, Judd, Suzanne E, Kissela, Brett M, Lichtman, Judith H, Lisabeth, Lynda D, Liu, Simin, Mackey, Rachel H, Magid, David J, McGuire, Darren K, Mohler, Emile R, Moy, Claudia S, Muntner, Paul, Mussolino, Michael E, Nasir, Khurram, Neumar, Robert W, Nichol, Graham, Palaniappan, Latha, Pandey, Dilip K, Reeves, Mathew J, Rodriguez, Carlos J, Rosamond, Wayne, Sorlie, Paul D, Stein, Joel, Towfighi, Amytis, Turan, Tanya N, Virani, Salim S, Woo, Daniel, Yeh, Robert W, Turner, Melanie B, American Heart Association Statistics Committee, and Stroke Statistics Subcommittee

Subjects
Writing Group Members, American Heart Association Statistics Committee, Stroke Statistics Subcommittee, Humans, Heart Diseases, Data Interpretation, Statistical, Health Behavior, American Heart Association, United States, Stroke, Research Report, AHA Scientific Statements, cardiovascular diseases, epidemiology, risk factors, statistics, stroke, Data Interpretation, Statistical, Clinical Sciences, Cardiorespiratory Medicine and Haematology, Public Health and Health Services, Cardiovascular System & Hematology
Published
2016

53. Heart Disease and Stroke Statistics-2016 Update: A Report From the American Heart Association.

Author

Writing Group Members, Mozaffarian, Dariush, Benjamin, Emelia J, Go, Alan S, Arnett, Donna K, Blaha, Michael J, Cushman, Mary, Das, Sandeep R, de Ferranti, Sarah, Després, Jean-Pierre, Fullerton, Heather J, Howard, Virginia J, Huffman, Mark D, Isasi, Carmen R, Jiménez, Monik C, Judd, Suzanne E, Kissela, Brett M, Lichtman, Judith H, Lisabeth, Lynda D, Liu, Simin, Mackey, Rachel H, Magid, David J, McGuire, Darren K, Mohler, Emile R, Moy, Claudia S, Muntner, Paul, Mussolino, Michael E, Nasir, Khurram, Neumar, Robert W, Nichol, Graham, Palaniappan, Latha, Pandey, Dilip K, Reeves, Mathew J, Rodriguez, Carlos J, Rosamond, Wayne, Sorlie, Paul D, Stein, Joel, Towfighi, Amytis, Turan, Tanya N, Virani, Salim S, Woo, Daniel, Yeh, Robert W, Turner, Melanie B, American Heart Association Statistics Committee, and Stroke Statistics Subcommittee

Subjects
Writing Group Members, American Heart Association Statistics Committee, Stroke Statistics Subcommittee, Humans, Heart Diseases, Data Interpretation, Statistical, Life Style, American Heart Association, United States, Stroke, Research Report, AHA Scientific Statements, cardiovascular diseases, epidemiology, risk factors, statistics, stroke, Data Interpretation, Statistical, Clinical Sciences, Cardiorespiratory Medicine and Haematology, Public Health and Health Services, Cardiovascular System & Hematology
Published
2016

55. Risk Prediction of Dementia in Middle‐aged and Older Adults: The Dementia Risk Prediction Pooling (DRPP) Consortium

Author

Allen, Norrina, primary, Krefman, Amy, additional, Stephan, John, additional, Yu, Jingzhi, additional, Carolan, Padraig, additional, Sedaghat, Sanaz, additional, Mansolf, Maxwell, additional, Soumare, Aicha, additional, Gross, Alden L., additional, Aiello, Allison, additional, Singh‐Manoux, Archana, additional, Ikram, M. Arfan, additional, Helmer, Catherine, additional, Tzourio, Christophe, additional, Satizabal, Claudia L., additional, Levine, Deborah A, additional, Lloyd‐Jones, Donald, additional, Briceno, Emily M, additional, Sorond, Farzaneh, additional, Wolters, Frank J., additional, Himali, Jayandra Jung, additional, Launer, Lenore J J., additional, Zhao, Lihui, additional, Lopez, Oscar L., additional, Debette, Stéphanie, additional, Seshadri, Sudha, additional, Judd, Suzanne E, additional, Hughes, Tim M., additional, Gudnason, Vilmundur, additional, and Scholtens, Denise, additional

Published
2023
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56. Accordance to a MIND–Style Diet is Associated with Decreased Risk of Dementia Mortality in the REasons for Geographic and Racial Disparities in Stroke (REGARDS) Cohort

Author

Judd, Suzanne E, primary, Howard, George, additional, Tangney, Christy C, additional, Pearson, Keith, additional, Shikany, James M, additional, Cushman, Mary, additional, Wilson, Nicole, additional, Howard, Virginia J, additional, Sawyer, Russell, additional, Oladele, Carol, additional, and Manly, Jennifer J., additional

Published
2023
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57. Prediction of Dementia Using Machine Learning Methods within a Large Pooled Consortia: The Dementia Risk Prediction Pooling (DRPP) Consortium

Author

Yu, Jingzhi, primary, Stephan, John, additional, Krefman, Amy, additional, Carolan, Padraig, additional, Sedaghat, Sanaz, additional, Mansolf, Maxwell, additional, Soumare, Aicha, additional, Gross, Alden L., additional, Aiello, Allison, additional, Singh‐Manoux, Archana, additional, Ikram, M. Arfan, additional, Helmer, Catherine, additional, Tzourio, Christophe, additional, Satizabal, Claudia L., additional, Levine, Deborah A, additional, Lloyd‐Jones, Donald, additional, Briceno, Emily M, additional, Sorond, Farzaneh, additional, Wolters, Frank J., additional, Himali, Jayandra Jung, additional, Launer, Lenore J J., additional, Zhao, Lihui, additional, Lopez, Oscar L., additional, Seshadri, Sudha, additional, Debette, Stéphanie, additional, Judd, Suzanne E, additional, Hughes, Tim M., additional, Gudnason, Vilmundur, additional, Scholtens, Denise, additional, and Allen, Norrina, additional

Published
2023
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58. Abstract 11396: Circulating Biomarkers Improve ChA 2 DS 2 -VASC Risk Prediction in Atrial Fibrillation: The CHA 2 DS 2 -VASc-Biomarkers Model

Author

Short, Samuel, primary, Hald, Erin, additional, Wilkinson, Katherine, additional, Howard, George, additional, Howard, Virginia J, additional, Judd, Suzanne E, additional, Soliman, Elsayed Z, additional, Kissela, Brett M, additional, Robinson, David, additional, Stanton, Robert J, additional, and Cushman, Mary, additional

Published
2023
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68. Executive Summary

Author

Mozaffarian, Dariush, Benjamin, Emelia J, Go, Alan S, Arnett, Donna K, Blaha, Michael J, Cushman, Mary, de Ferranti, Sarah, Després, Jean-Pierre, Fullerton, Heather J, Howard, Virginia J, Huffman, Mark D, Judd, Suzanne E, Kissela, Brett M, Lackland, Daniel T, Lichtman, Judith H, Lisabeth, Lynda D, Liu, Simin, Mackey, Rachel H, Matchar, David B, McGuire, Darren K, Mohler, Emile R, Moy, Claudia S, Muntner, Paul, Mussolino, Michael E, Nasir, Khurram, Neumar, Robert W, Nichol, Graham, Palaniappan, Latha, Pandey, Dilip K, Reeves, Mathew J, Rodriguez, Carlos J, Sorlie, Paul D, Stein, Joel, Towfighi, Amytis, Turan, Tanya N, Virani, Salim S, Willey, Joshua Z, Woo, Daniel, Yeh, Robert W, and Turner, Melanie B

Subjects
Cardiorespiratory Medicine and Haematology, Clinical Sciences, Public Health and Health Services, Cardiovascular System & Hematology
Published
2015

69. Executive Summary: Heart Disease and Stroke Statistics-2015 Update A Report From the American Heart Association

Author

Mozaffarian, Dariush, Benjamin, Emelia J, Go, Alan S, Arnett, Donna K, Blaha, Michael J, Cushman, Mary, de Ferranti, Sarah, Despres, Jean-Pierre, Fullerton, Heather J, Howard, Virginia J, Huffman, Mark D, Judd, Suzanne E, Kissela, Brett M, Lackland, Daniel T, Lichtman, Judith H, Lisabeth, Lynda D, Liu, Simin, Mackey, Rachel H, Matchar, David B, McGuire, Darren K, III, Mohler Emile R, Moy, Claudia S, Muntner, Paul, Mussolino, Michael E, Nasir, Khurram, Neumar, Robert W, Nichol, Graham, Palaniappan, Latha, Pandey, Dilip K, Reeves, Mathew J, Rodriguez, Carlos J, Sorlie, Paul D, Stein, Joel, Towfighi, Amytis, Turan, Tanya N, Virani, Salim S, Willey, Joshua Z, Woo, Daniel, Yeh, Robert W, Turner, Melanie B, Comm, Amer Heart Assoc Stat, and Subcomm, Stroke Stat

Subjects
Clinical Sciences, Cardiorespiratory Medicine and Haematology, Public Health and Health Services, Cardiovascular System & Hematology
Published
2015

70. Heart disease and stroke statistics--2015 update: a report from the American Heart Association.

Author

Mozaffarian, Dariush, Benjamin, Emelia J, Go, Alan S, Arnett, Donna K, Blaha, Michael J, Cushman, Mary, de Ferranti, Sarah, Després, Jean-Pierre, Fullerton, Heather J, Howard, Virginia J, Huffman, Mark D, Judd, Suzanne E, Kissela, Brett M, Lackland, Daniel T, Lichtman, Judith H, Lisabeth, Lynda D, Liu, Simin, Mackey, Rachel H, Matchar, David B, McGuire, Darren K, Mohler, Emile R, Moy, Claudia S, Muntner, Paul, Mussolino, Michael E, Nasir, Khurram, Neumar, Robert W, Nichol, Graham, Palaniappan, Latha, Pandey, Dilip K, Reeves, Mathew J, Rodriguez, Carlos J, Sorlie, Paul D, Stein, Joel, Towfighi, Amytis, Turan, Tanya N, Virani, Salim S, Willey, Joshua Z, Woo, Daniel, Yeh, Robert W, Turner, Melanie B, and American Heart Association Statistics Committee and Stroke Statistics Subcommittee

Subjects
American Heart Association Statistics Committee and Stroke Statistics Subcommittee, Humans, Heart Diseases, Risk Reduction Behavior, American Heart Association, United States, Stroke, Research Report, AHA Scientific Statements, cardiovascular diseases, epidemiology, risk factors, statistics, stroke, Cardiorespiratory Medicine and Haematology, Clinical Sciences, Public Health and Health Services, Cardiovascular System & Hematology
Published
2015

76. Heart Disease and Stroke Statistics—2014 Update

Author

Go, Alan S, Mozaffarian, Dariush, Roger, Véronique L, Benjamin, Emelia J, Berry, Jarett D, Blaha, Michael J, Dai, Shifan, Ford, Earl S, Fox, Caroline S, Franco, Sheila, Fullerton, Heather J, Gillespie, Cathleen, Hailpern, Susan M, Heit, John A, Howard, Virginia J, Huffman, Mark D, Judd, Suzanne E, Kissela, Brett M, Kittner, Steven J, Lackland, Daniel T, Lichtman, Judith H, Lisabeth, Lynda D, Mackey, Rachel H, Magid, David J, Marcus, Gregory M, Marelli, Ariane, Matchar, David B, McGuire, Darren K, Mohler, Emile R, Moy, Claudia S, Mussolino, Michael E, Neumar, Robert W, Nichol, Graham, Pandey, Dilip K, Paynter, Nina P, Reeves, Matthew J, Sorlie, Paul D, Stein, Joel, Towfighi, Amytis, Turan, Tanya N, Virani, Salim S, Wong, Nathan D, Woo, Daniel, and Turner, Melanie B

Subjects
American Heart Association, Cardiology, Heart Diseases, Humans, Stroke, United States, AHA Scientific Statements, cardiovascular diseases, epidemiology, risk factors, statistics, stroke, American Heart Association Statistics Committee and Stroke Statistics Subcommittee, Cardiorespiratory Medicine and Haematology, Clinical Sciences, Public Health and Health Services, Cardiovascular System & Hematology
Abstract

Each year, the American Heart Association (AHA), in conjunction with the Centers for Disease Control and Prevention, the National Institutes of Health, and other government agencies, brings together the most up-to-date statistics on heart disease, stroke, other vascular diseases, and their risk factors and presents them in its Heart Disease and Stroke Statistical Update. The Statistical Update is a critical resource for researchers, clinicians, healthcare policy makers, media professionals, the lay public, and many others who seek the best available national data on heart disease, stroke, and other cardiovascular disease-related morbidity and mortality and the risks, quality of care, use of medical procedures and operations, and costs associated with the management of these diseases in a single document. Indeed, since 1999, the Statistical Update has been cited >10 500 times in the literature, based on citations of all annual versions. In 2012 alone, the various Statistical Updates were cited ≈3500 times (data from Google Scholar). In recent years, the Statistical Update has undergone some major changes with the addition of new chapters and major updates across multiple areas, as well as increasing the number of ways to access and use the information assembled. For this year's edition, the Statistics Committee, which produces the document for the AHA, updated all of the current chapters with the most recent nationally representative data and inclusion of relevant articles from the literature over the past year. This year's edition includes a new chapter on peripheral artery disease, as well as new data on the monitoring and benefits of cardiovascular health in the population, with additional new focus on evidence-based approaches to changing behaviors, implementation strategies, and implications of the AHA's 2020 Impact Goals. Below are a few highlights from this year's Update. © 2013 American Heart Association, Inc.

Published
2014

77. Executive Summary

Author

Go, Alan S, Mozaffarian, Dariush, Roger, Véronique L, Benjamin, Emelia J, Berry, Jarett D, Blaha, Michael J, Dai, Shifan, Ford, Earl S, Fox, Caroline S, Franco, Sheila, Fullerton, Heather J, Gillespie, Cathleen, Hailpern, Susan M, Heit, John A, Howard, Virginia J, Huffman, Mark D, Judd, Suzanne E, Kissela, Brett M, Kittner, Steven J, Lackland, Daniel T, Lichtman, Judith H, Lisabeth, Lynda D, Mackey, Rachel H, Magid, David J, Marcus, Gregory M, Marelli, Ariane, Matchar, David B, McGuire, Darren K, Mohler, Emile R, Moy, Claudia S, Mussolino, Michael E, Neumar, Robert W, Nichol, Graham, Pandey, Dilip K, Paynter, Nina P, Reeves, Matthew J, Sorlie, Paul D, Stein, Joel, Towfighi, Amytis, Turan, Tanya N, Virani, Salim S, Wong, Nathan D, Woo, Daniel, and Turner, Melanie B

Subjects
American Heart Association, Cardiology, Heart Diseases, Humans, Prevalence, Research Report, Risk Factors, Stroke, United States, AHA Scientific Statements, cardiovascular diseases, epidemiology, risk factors, statistics, stroke, American Heart Association Statistics Committee and Stroke Statistics Subcommittee, Cardiorespiratory Medicine and Haematology, Clinical Sciences, Public Health and Health Services, Cardiovascular System & Hematology
Abstract

Each year, the American Heart Association (AHA), in conjunction with the Centers for Disease Control and Prevention, the National Institutes of Health, and other government agencies, brings together the most up-to-date statistics on heart disease, stroke, other vascular diseases, and their risk factors and presents them in its Heart Disease and Stroke Statistical Update. The Statistical Update is a critical resource for researchers, clinicians, healthcare policy makers, media professionals, the lay public, and many others who seek the best available national data on heart disease, stroke, and other cardiovascular disease-related morbidity and mortality and the risks, quality of care, use of medical procedures and operations, and costs associated with the management of these diseases in a single document. Indeed, since 1999, the Statistical Update has been cited >10 500 times in the literature, based on citations of all annual versions. In 2012 alone, the various Statistical Updates were cited ≈3500 times (data from Google Scholar). In recent years, the Statistical Update has undergone some major changes with the addition of new chapters and major updates across multiple areas, as well as increasing the number of ways to access and use the information assembled. For this year's edition, the Statistics Committee, which produces the document for the AHA, updated all of the current chapters with the most recent nationally representative data and inclusion of relevant articles from the literature over the past year. This year's edition includes a new chapter on peripheral artery disease, as well as new data on the monitoring and benefits of cardiovascular health in the population, with additional new focus on evidence-based approaches to changing behaviors, implementation strategies, and implications of the AHA's 2020 Impact Goals. Below are a few highlights from this year's Update. © 2013 American Heart Association, Inc.

Published
2014

78. Executive summary: heart disease and stroke statistics--2014 update: a report from the American Heart Association.

Author

Go, Alan S, Mozaffarian, Dariush, Roger, Véronique L, Benjamin, Emelia J, Berry, Jarett D, Blaha, Michael J, Dai, Shifan, Ford, Earl S, Fox, Caroline S, Franco, Sheila, Fullerton, Heather J, Gillespie, Cathleen, Hailpern, Susan M, Heit, John A, Howard, Virginia J, Huffman, Mark D, Judd, Suzanne E, Kissela, Brett M, Kittner, Steven J, Lackland, Daniel T, Lichtman, Judith H, Lisabeth, Lynda D, Mackey, Rachel H, Magid, David J, Marcus, Gregory M, Marelli, Ariane, Matchar, David B, McGuire, Darren K, Mohler, Emile R, Moy, Claudia S, Mussolino, Michael E, Neumar, Robert W, Nichol, Graham, Pandey, Dilip K, Paynter, Nina P, Reeves, Matthew J, Sorlie, Paul D, Stein, Joel, Towfighi, Amytis, Turan, Tanya N, Virani, Salim S, Wong, Nathan D, Woo, Daniel, Turner, Melanie B, and American Heart Association Statistics Committee and Stroke Statistics Subcommittee

Subjects
American Heart Association Statistics Committee and Stroke Statistics Subcommittee, Humans, Heart Diseases, Prevalence, Risk Factors, Cardiology, American Heart Association, United States, Stroke, Research Report, AHA Scientific Statements, cardiovascular diseases, epidemiology, risk factors, statistics, stroke, Cardiovascular System & Hematology, Cardiorespiratory Medicine and Haematology, Clinical Sciences, Public Health and Health Services
Published
2014

79. Associations between dietary habits, socio-demographics and gut microbial composition in adolescents.

Author

Kemp, Keri M., Orihuela, Catheryn A., Morrow, Casey D., Judd, Suzanne E., Evans, Retta R., and Mrug, Sylvie

Subjects
FOOD habits, GUT microbiome, MULTIVARIATE analysis, MULTIPLE regression analysis, RNA, IN vitro meat, DESCRIPTIVE statistics, GENE expression profiling, SOCIAL classes, SOCIODEMOGRAPHIC factors, EMOTION regulation, NATURAL foods
Abstract

The relationship between dietary habits and microbiota composition during adolescence has not been well examined. This is a crucial knowledge gap to fill considering that diet–microbiota interactions influence neurodevelopment, immune system maturation and metabolic regulation. This study examined the associations between diet and the gut microbiota in a school-based sample of 136 adolescents (M age = 12·1 years; age range 11–13 years; 48 % female; 47 % Black, 38 % non-Hispanic White, 15 % Hispanic or other minorities) from urban, suburban and rural areas in the Southeast USA. Adolescents completed the Rapid Eating Assessment for Participants and provided stool samples for 16S ribosomal RNA gene sequencing. Parents reported their child and family socio-demographic characteristics. The associations between diet and socio-demographics with gut microbiota diversity and abundance were analysed using multivariable regression models. Child race and ethnicity, sex, socio-economic status and geographic locale contributed to variation within microbiota composition (β -diversity). Greater consumption of processed meat was associated with a lower microbial α -diversity after adjusting for socio-demographic variables. Multi-adjusted models showed that frequent consumption of nutrient-poor, energy-dense foods (e.g. sugar-sweetened beverages, fried foods, sweets) was negatively associated with abundances of genera in the family Lachnospiraceae (Anaerostipes , Fusicatenibacter and Roseburia), which are thought to play a beneficial role in host health through their production of short-chain fatty acids (SCFAs). These results provide new insights into the complex relationships among socio-demographic factors, diet and gut microbiota during adolescence. Adolescence may represent a critical window of opportunity to promote healthy eating practices that shape a homoeostatic gut microbiota with life-long benefits. [ABSTRACT FROM AUTHOR]

Published
2024
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80. A Segmented Regression Analysis of Household Income and Recurrent Falls Among Adults in a National Cohort Study.

Author

Brown, Janene, Hirsch, Jana A., Tabb, Loni Philip, Judd, Suzanne E, Bennett, Aleena, Rundle, Andrew, and Lovasi, Gina S

Subjects
FAMILIES & economics, STATISTICS, CONFIDENCE intervals, ECONOMIC status, REGRESSION analysis, POPULATION geography, RACE, INCOME, DISEASE relapse, RISK assessment, ACCIDENTAL falls, TIME series analysis, RESEARCH funding, RESIDENTIAL patterns, POVERTY, ODDS ratio, LONGITUDINAL method, DISEASE risk factors, OLD age
Abstract

Falls can have life-altering consequences for older adults, including extended recovery periods and compromised independence. Higher household income may mitigate the risk of falls by providing financial resources for mobility tools, remediation of environmental hazards, and needed supports, or it may buffer the impact of an initial fall on subsequent risk through improved assistance and care. Household income has not had a consistently observed association with falls in older adults; however, a segmented association may exist such that associations are attenuated above a certain income threshold. In this study, we utilized segmented negative binomial regression analysis to examine the association between household income and recurrent falls among 2,302 participants in the Reasons for Geographic and Racial Differences in Stroke (REGARDS) Study recruited between 2003 and 2007. Income-fall association segments separated by changes in slope were considered. Model results indicated a 2-segment association between household income and recurrent falls in the past year. In the range below the breakpoint, household income was negatively associated with the rate of recurrent falls across all age groups examined; in a higher income range (from $20,000–$49,999 to ≥$150,000), the association was attenuated (weaker negative trend) or reversed (positive trend). These findings point to potential benefits of ensuring that incomes for lower-income adults exceed the threshold needed to confer a reduced risk of recurrent falls. [ABSTRACT FROM AUTHOR]

Published
2024
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81. Changes in Adiposity and Cognitive Function in Older Adults: The REGARDS Study.

Author

Zhu, Wenfei, Li, Yanbing, Zhao, Chenxi, Howard, Virginia J, Wadley, Virginia G, Judd, Suzanne E, Colabianchi, Natalie, McClure, Leslie A, Hooker, Steven P, and Sun, Yuliang

Subjects
COGNITION disorder risk factors, RESEARCH, MEMORY, EXECUTIVE function, MENTAL orientation, FUNCTIONAL status, AGE distribution, REGRESSION analysis, PSYCHOLOGICAL tests, RISK assessment, WAIST circumference, ATTRIBUTION (Social psychology), DESCRIPTIVE statistics, RESEARCH funding, WHITE people, STATISTICAL correlation, BODY mass index, LOGISTIC regression analysis, ADIPOSE tissues, COGNITION in old age, AFRICAN Americans, OLD age
Abstract

Objectives Adiposity may have a role in the risk of dementia. Fewer studies have focused on the relationship between change in adiposity and cognitive decline. Our study aimed to explore the association between the change in adiposity and cognitive function in Black and White older adults. Methods The participants were 12,204 older adults without cognitive impairment (62.8 ± 8.0 years) in the United States. The percent body mass index change (%BMI change) and percent waist circumference change (%WC change) were measured at 2 in-home visits (first: 2003–2007, second: 2013–2016). Cognitive status was assessed by the Six-Item Screener annually. Memory and executive function were measured by word list learning, MOCA recall and orientation, and letter and animal fluency every 2 years. Logistic regression or linear regression models were used to estimate the relationship between percent change in adiposity and cognitive function. Results After 12.7 ± 1.7 years, a greater decrease in %BMI change or %WC change was significantly associated with a higher risk of cognitive impairment. Compared to older adults with −5% ≤ change ≤ 5% from baseline, a significantly higher risk of cognitive impairment and greater loss in memory and executive function were found among those who experienced more than a 10% decline in %BMI change or %WC change. Older adults who experienced a 5%–10% decrease in %BMI change had a higher risk of cognitive impairment and greater loss of memory compared to those with −5% ≤ change ≤ 5%. Discussion A greater decrease in %BMI (>5%) and %WC (>10%) change was associated with greater cognitive loss observed over time. [ABSTRACT FROM AUTHOR]

Published
2024
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84. Strong protective effect of theAPOL1p.N264K variant against G2-associated focal segmental glomerulosclerosis and kidney disease

Author

Gupta, Yask, primary, Friedman, David J., additional, McNulty, Michelle, additional, Khan, Atlas, additional, Lane, Brandon, additional, Wang, Chen, additional, Ke, Juntao, additional, Jin, Gina, additional, Wooden, Benjamin, additional, Knob, Andrea L., additional, Lim, Tze Y., additional, Appel, Gerald B., additional, Huggins, Kinsie, additional, Liu, Lili, additional, Mitrotti, Adele, additional, Stangl, Megan C., additional, Bomback, Andrew, additional, Westland, Rik, additional, Bodria, Monica, additional, Marasa, Maddalena, additional, Shang, Ning, additional, Cohen, David J., additional, Crew, Russell J., additional, Morello, William, additional, Canetta, Pietro, additional, Radhakrishnan, Jai, additional, Martino, Jeremiah, additional, Liu, Qingxue, additional, Chung, Wendy K., additional, Espinoza, Angelica, additional, Luo, Yuan, additional, Wei, Wei-Qi, additional, Feng, Qiping, additional, Weng, Chunhua, additional, Fang, Yilu, additional, Kullo, Iftikhar J., additional, Naderian, Mohammadreza, additional, Limdi, Nita, additional, Irvin, Marguerite R., additional, Tiwari, Hemant, additional, Mohan, Sumit, additional, Rao, Maya, additional, Dube, Geoffrey, additional, Chaudhary, Ninad S., additional, Gutiérrez, Orlando M., additional, Judd, Suzanne E., additional, Cushman, Mary, additional, Lange, Leslie A., additional, Lange, Ethan M., additional, Bivona, Daniel L., additional, Verbitsky, Miguel, additional, Winkler, Cheryl A., additional, Kopp, Jeffrey B., additional, Santoriello, Dominick, additional, Batal, Ibrahim, additional, Brant Pinheiro, Sérgio Veloso, additional, Araújo Oliveira, Eduardo, additional, e Silva, Ana Cristina Simoes, additional, Pisani, Isabella, additional, Fiaccadori, Enrico, additional, Lin, Fangming, additional, Gesualdo, Loreto, additional, Amoroso, Antonio, additional, Ghiggeri, Gian Marco, additional, D’Agati, Vivette D., additional, Magistroni, Riccardo, additional, Kenny, Eimear E., additional, Loos, Ruth J.F., additional, Montini, Giovanni, additional, Hildebrandt, Friedhelm, additional, Paul, Dirk S., additional, Petrovski, Slavé, additional, Goldstein, David B., additional, Kretzler, Matthias, additional, Gbadegesin, Rasheed, additional, Gharavi, Ali G., additional, Kiryluk, Krzysztof, additional, Sampson, Matthew G., additional, Pollak, Martin R., additional, and Sanna-Cherchi, Simone, additional

Published
2023
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88. Healthy Behaviors, Risk Factor Control and Awareness of Chronic Kidney Disease

Author

Tuot, Delphine S, Plantinga, Laura C, Judd, Suzanne E, Muntner, Paul, Hsu, Chi-yuan, Warnock, David G, Gutiérrez, Orlando M, Safford, Monika, Powe, Neil R, and McClellan, William M

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Behavioral and Social Science, Cardiovascular, Kidney Disease, Hypertension, Prevention, Clinical Research, 3.1 Primary prevention interventions to modify behaviours or promote wellbeing, Prevention of disease and conditions, and promotion of well-being, Renal and urogenital, Good Health and Well Being, Aged, Aged, 80 and over, Angiotensin Receptor Antagonists, Angiotensin-Converting Enzyme Inhibitors, Anti-Inflammatory Agents, Non-Steroidal, Blood Glucose, Blood Pressure, Confidence Intervals, Female, Health Behavior, Health Knowledge, Attitudes, Practice, Humans, Logistic Models, Male, Middle Aged, Motor Activity, Odds Ratio, Renal Insufficiency, Chronic, Risk Reduction Behavior, Smoking, Chronic kidney disease, Awareness, Self-management, Behaviors, REGARDS Investigators, Urology & Nephrology, Clinical sciences
Abstract

Background/aimsThe association between chronic kidney disease (CKD) awareness and healthy behaviors is unknown. We examined whether CKD self-recognition is associated with healthy behaviors and achieving risk-reduction targets known to decrease risk of cardiovascular morbidity and CKD progression.MethodsCKD awareness, defined as a 'yes' response to 'Has a doctor or other health professional ever told you that you had kidney disease?', was examined among adults with CKD (eGFR

Published
2013

91. Alpha globin gene copy number and incident ischemic stroke risk among Black Americans

Author

Ruhl, A. Parker, primary, Jeffries, Neal, additional, Yang, Yu, additional, Brooks, Steven D., additional, Naik, Rakhi P., additional, Pecker, Lydia H., additional, Mott, Bryan T., additional, Winkler, Cheryl A., additional, Armstrong, Nicole D., additional, Zakai, Neil A., additional, Gutierrez, Orlando M., additional, Judd, Suzanne E., additional, Howard, Virginia J., additional, Howard, George, additional, Irvin, Marguerite R., additional, Cushman, Mary, additional, and Ackerman, Hans C., additional

Published
2023
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97. The Vitamin D for Enhancing the Immune System in Cystic Fibrosis (DISC) trial: Rationale and design of a multi-center, double-blind, placebo-controlled trial of high dose bolus administration of vitamin D3 during acute pulmonary exacerbation of cystic fibrosis

Author

Tangpricha, Vin, Smith, Ellen M., Binongo, Jose, Judd, Suzanne E., Ziegler, Thomas R., Walker, Seth, Tirouvanziam, Rabindra, Zughaier, Susu M., Lee, Moon Jeong, Chesdachai, Supavit, Hermes, Wendy A., Chmiel, James F., Gaggar, Amit, Grossmann, Ruth E., Joseph, Patricia M., and Alvarez, Jessica A.

Published
2017
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