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Summary: This research studies the factor structure of the Karolinska Scales of Personality (KSP) and its location within Eysenck's three broad dimensions of personality: psychoticism, extraversion, and neuroticism. A series of factor analyses and structural equations with the KSP and the Eysenck Personality Questionnaire-Revised (EPQ-R) scales were carried out. The relationships between KSP and other biologically rooted personality traits (Zuckerman's sensation seeking and Gray's sensitivity to punishment) were also investigated. The results showed four underlying traits of the KSP: negative emotionality, aggressive nonconformity, impulsive unsocialized sensation seeking, and social withdrawal. Negative emotionality was mainly related to neuroticism; aggressive nonconformity was associated with psychoticism and, to a lesser degree, with neuroticism; impulsive unsocialized sensation seeking was correlated with both psychoticism and extraversion; and social withdrawal was principally related to low extraversion.

Background. The diversity of pharmacological actions of antidepressants suggests that they may bring about their clinical effects by different functional means.Methods. Twenty healthy volunteers were randomized in a cross-over design to receive 2 weeks of a clinical dose of both reboxetine and sertraline. Baseline assessments of personality were made using the Cloninger Tridimensional Personality Questionnaire and the Karolinska Scales of Personality. Daily and weekly ratings of mood (POMS and PANAS) and quality of life (SASS) were undertaken.Results. Reboxetine and sertraline differed in their effects on the SASS as well as on measures of mood. Reboxetine appeared more likely to be energy enhancing; the effects of sertraline were more difficult to quantify. Personality factors, such as harm avoidance predicted the preference of subjects for these effects and the effect of being on a preferred drug had a significant impact on SASS, and ratings of moods as well as on self-assessments of personality.Conclusions. The differences reported here are consistent with the original thinking that led to the development of the SSRIs. The findings point to the need for further research on possible differential functional effects of psychotropic agents selective to different brain systems. The findings also have implications for clinical practice, in particular for maintenance treatment with antidepressants.

The study was performed to investigate the relationship between perceived muscle tension and electromyographic hyperactivity and to what extent electromyographic (EMG) hyperactivity relates to personality traits in fibromyalgics. Thirty-six females with fibromyalgia performed isokinetic maximal forward flexions of the shoulder combined with surface EMG recordings of the trapezius and infraspinatus muscles. Signal amplitude ratio and peak torque were calculated in the initial and endurance test phases. Pain intensity, perceived general and local shoulder muscle tension, and personality traits using the Karolinska Scales of Personality were assessed pre-test. Neither perceived muscle tension nor muscular tension personality trait correlated with EMG muscle hyperactivity. Perceived general muscle tension correlated with aspects of anxiety proneness (including muscle tension) of the Karolinska Scales of Personality. Pain intensity interacted with many of the variables. We propose that when patients with fibromyalgia report muscle tension that they may be expressing something other than physiological muscle tension.

The question of subgroups in eating disorders was addressed in this study. According to the Diagnostic and Statistical Manual of Mental Disorders, IV, the two subtypes for anorexia nervosa are restricting and binge-eating/purging. For bulimia nervosa, the subtypes are purging and nonpurging. An attempt was made here to examine alternative ways to create meaningful subgroups in the eating-disordered patient group. A cluster analysis was performed in a group of 52 female patients (AN=21, BN=31). Fifty-five undergraduate students served as a control group. Three self-report instruments were used: the Eating Disorder Inventory-2, Karolinska Scales of Personality, and Tennessee Self-Concept Scale. The results reveal three different groups of patients. Factors like poor interoceptive ability and high degree of somatization differentiate between the groups, and contribute to severity of pathology, as well as to lower levels of self-concept.The results reveal three different groups of patients. Factors like poor interoceptive ability and high degree of somatization differentiate between the groups, and contribute to severity of pathology, as well as to lower levels of self-concept.

Background: A Swedish male criminal population was grouped into personality disorder subgroups and investigated with regard to personality traits and platelet monoamine oxidase (MAO) activity. The main aim of the study was to examine the possibility of a risk factor combination by having low platelet MAO activity as well as belonging to a certain diagnostic DSM-IV axis I (drug abuse in the present series) and/or II subgroup. Methods: Personality disorders were grouped into clusters according to the cluster system used in DSM-IV axis II. The prisoners were grouped into five subgroups and each subject completed the Karolinska Scales of Personality self-report questionnaire. The comparison group for the personality data comprised 51 non-criminal males from a longitudinal Swedish project. Platelet MAO activity was assessed for the criminals as well as for a control group including 60 non-criminal healthy male Caucasians. For testing the existence of syndromes, a configuration frequency analysis (CFA) was used. Results: The results showed low scores on the socialisation and high scores on the sensation seeking-related traits impulsiveness and monotony avoidance, and the somatic anxiety-related muscular tension in the criminals with any DSM-IV mental disorder, however most markedly in cluster AB and cluster B subjects. In addition, cluster AB subjects had significantly lower platelet MAO activity than controls. Two significant ‘types’ were found among the criminals: one was characterised by low platelet MAO activity, cluster B personality diagnosis as well as drug abuse disorder diagnosis; and the other by a pattern of normal platelet MAO activity, no cluster B personality disorder and no drug abuse disorder diagnosis. Conclusion: The aggregation of certain risk factors in the same individual has been shown to contribute to the development of criminal behaviour.

SummaryThe relationship between suicide attempts and different vulnerability factors was investigated in 61 male subjects during forensic psychiatric examination. Personality traits and psychopathy were determined by means of the Karolinska Scales of Personality (KSP) and the Psychopathy Checklist-Revised (PCL-R). Clinical diagnoses were determined by the use of Structured Clinical Interview for DSM-III-R (SCID). Platelet monoamine oxidase (MAO) activity was investigated in 58 subjects.Suicide attempters had extremely low socialization and high impulsive aggression. This was independent of a history of repeatedly criminal violence or not. They had higher PCL-R scores and lower levels of platelet MAO activity than non-attempters. No relationship was found between suicide attempts and repeated violent criminality. However, among the subjects with repeated criminal violence there was a highly significant difference between suicide attempters and non-attempters, indicating different personality profiles in violent offenders with and without suicidal behavior. Suicidal behavior was significantly associated with borderline personality disorder, but not with any other single DSM-III-R disorder. The results show a far more severe personality disturbance in suicide attempters than in other violent patients in this type of population. Suicidal behavior should therefore be evaluated and treated per se.

The purpose of the present study was to investigate personality traits and platelet monoamine oxidase (MAO) activity, as well as occurrence of personality disorder criteria, family characteristics, and criminal activity as related to misuse patt ern in a sample of female in-patients with severe alcohol dependence. In accordance with theoretical assumptions and empirical findings of underlying neurobiological correlates of disinhibition in individuals with double or multiple misuse patterns, the female alcoh olics were divided into subgroups with: (1) alcohol as their single drug of misuse (ALC; n = 16); (2) a history of additional substance misuse (ALC-DRUG; n = 11). Platelet MAO activity of the female subgroups was studied in comparison to a control group of non-clinical female subjects. Marked differences were obtained between the two subgroups. The ALC-DRUG females scored significantly higher with regard to Karolinska Scales of Personality (KSP) impulsiveness, anxiety-related traits, and non-conformity, displayed high er fre- quency of depression in first degree relatives, were more frequently involved in criminal activity, and more frequently diagnos ed for any personality disorder according to DSM-IV, axis II. Finally, the ALC-DRUG females displayed significantly lower platelet MAO activity than controls. In conclusion, the results support the usefulness of a classification of severe alcoholic female subjec ts according to having/not having a history of additional substance misuse. The present female alcoholics with a history of additional misus e formed a group of individuals fulfilling the criteria similar for male type 2 alcoholism.

Dopamine receptor gene variation has been hypothesized to influence personality traits characterized by novelty seeking and related traits. We analyzed a dopamine D3 receptor gene (DRD3) variant in a Swedish population (n = 373) investigated with one or more of several personality questionnaires. No significant relationships were found between DRD3 genotypes and any of the 15 Karolinska Scales of Personality (KSP) and five Health-relevant Personality 5 factor inventory (HP5i) scales. The DRD3 variant was associated with some scales related to novelty seeking: the Swedish universities Scales of Personality (SSP) Adventure Seeking and the revised NEO personality inventory (NEO-PI-R) Fantasy (O1) and Order (C2) scales. There were also associations with the Temperament and Character Inventory (TCI) Cooperativeness and Compassion (C4) scales. After correction for multiple testing, however, no significant difference remained. We conclude that the investigated DRD3 polymorphism does not have a major impact on personality in the investigated population. © 2003 Wiley-Liss, Inc.

The aim of the present study was to determine if Behavioural Inhibition System (BIS) functioning, as described by Gray (Gray, J.A.C. (1982). The Neuropsychology of anxiety: an enquiry into the functions of the Septo-Hippocampal system. Oxford: Oxford University Press), would be a core vulnerability for cluster C personality disorders (PD), that is, if these patients would show a higher anxiety trait (i.e. in Gray's terms) than patients with other PD or without Axis II disorders. A total sample of 77 out-patients was assessed with the Eysenck Personality Questionnaire, Sensitivity to Punishment and Sensitivity to Reward Scales, Karolinska Scales of Personality, and the Structured-Interview for DSM-III-R Personality Disorders (SCID-II). Analyses were conducted considering the following groups: presence of cluster C personality disorder/s, presence of clusters A/B personality disorder/s, absence of personality disorder (non-PD). As a second step, cluster C and non-PD groups were also subdivided according to the presence/absence of anxiety or affective Axis I symptoms. Overall, results showed higher scores on anxiety trait-related scales in the cluster C group. However, only Somatic Anxiety, Psychasthenia and Sensitivity to Punishment scales (SP) clearly distinguished cluster C from each one of the other two groups. After a second analysis, only the Sensitivity to Punishment scale showed independence from Axis I status while discriminating between cluster C and non-PD patients. Results were similar when only behavioural items from the SP scale were considered. From these results we can conclude that a higher BIS functioning would differentiate cluster C personality disorders from patients with other PD or without PD, and that considering only the behavioural anxiety component in their assessment, a low Axis I influence is obtained.

Several studies have reported an association between anxiety-related personality traits and a promoter polymorphism in the human serotonin transporter (5-HTT) gene (5-HTT gene-linked polymorphic region, 5-HTTLPR). In the present study, a population of 251 subjects was assessed with the Karolinska Scales of Personality (KSP) and genotyped both for the 5-HTTLPR and for a variable number of tandem repeats polymorphism in the second intron of the same gene. The interpretation of previous studies has to some extent been confounded by the studied subjects differing with respect to ethnicity, sex, and age. To circumvent this problem, all included subjects were Caucasians, women, and born in the same year (1956). Associations were found between the 5-HTTLPR and four of the five anxiety-related KSP scales (psychic anxiety, muscular tension, psychasthenia, and lack of assertiveness), subjects being homozygous for the short allele displaying higher anxiety scores than those of the long/long or long/short genotype. In addition, an association was found between the intron 2 polymorphism and one anxiety-related personality trait (somatic anxiety). © 2001 Wiley-Liss, Inc.

In contrast to other non-psychotic psychiatric populations, subjects with obsessive-compulsive disorder (OCD) are more prone to have personality disorder from cluster A (the odd and eccentric cluster). The present study aims at further investigating the relationship between these and other personality traits in OCD subjects and their relation to high functioning autism (HFA) and Asperger disorder. Sixty-four subjects with OCD were included. Personality traits were assessed with the Karolinska Scales of Personality (KSP), and personality disorders with DSM-adapted questionnaires. In addition, autistic traits were assessed in 29 videotaped subjects, by 3 independent raters. Twenty percent of the subjects with OCD were identified as also having autistic traits. These subjects scored higher on KSP scales measuring muscular tension, psychasthenia, and inhibition of aggression and lower on socialization as compared with OCD subjects without autistic traits. Additionally, subjects with autistic traits fulfilled criteria for anxious personality disorders and paranoid personality disorders significantly more often than subjects without autistic traits. We propose that OCD is often related to HFA and Asperger disorder. Self-report questionnaires may be useful in establishing the diagnosis. However, those with the most obvious autistic features seem to be less able to identify these traits in themselves.

Background; Lately there has been an increasing interest in whether personality traits are associated with criminal behaviour in male and female subjects. Criminality and alcohol abuse are often associated. Delinquent adolescents are impulsive and danger seeking. Childhood aggression may be a precursor of adult criminality. Method Using longitudinal data, adult personality and childhood behaviours were examined for groups of non-criminals and criminals of Finnish (n = 268) and Swedish (n + 169) samples, and crime groups were compared in the two cultures. Karolinska Scales of Personality (KSP) were given at adult age and the participants had been observed and rated by their teachers in respect of behaviour in childhood (at age 8 years and 13 years, respectively). Results Male offenders with alcohol problems (Finnish and Swedish) had significantly higher scores on psychopathy-related personality traits in adulthood than other subgroups, as indicated by higher impulsivity, muscular tension and lower socialization. They also displayed higher scores on teacher-rated aggressiveness in childhood than the non-criminal groups. The female subgroup displaying criminal activity was small. It did not differ significantly from non-offenders in adult personality characteristics. Female offenders, however, showed early indications of lower sociability (in Finland) and higher aggressiveness and disharmony in childhood than non-offenders (in Sweden). Discussion The study suggests that early problem behaviours are precursors of subsequent criminal activity in at least two cultures. The results emphasize the importance of longitudinal research programmes. Copyright © 2000 Whurr Publishers Ltd.

Transcription factor AP-2beta is implicated in playing an important role during embryonic development of different parts of the brain, eg, midbrain, hindbrain, spinal cord, dorsal and cranial root ganglia.1,2 The gene encoding AP-2beta contains a polymorphic region which includes a tetranucleotide repeat of [CAAA] four or five times, located in intron 2 between nucleotides 12593 and 12612.3 Since the midbrain contains structures important for variables such as mood and personality, we have investigated if the AP-2beta genotype is associated with personality traits estimated by the Karolinska Scales of Personality (KSP). Identification of transcription factor genes as candidate genes in psychiatric disorders is a novel approach to further elucidate the genetic factors that, together with environmental factors, are involved in the expression of specific psychiatric phenotypes. The AP-2beta genotype and KSP scores were determined for 137 Caucasian volunteers (73 females and 64 males). The personality traits muscular tension, guilt, somatic anxiety, psychastenia and indirect aggression were significantly associated with the specific AP-2beta genotype, albeit with significant difference between genders. Based on this result the human AP-2beta gene seems to be an important candidate gene for personality disorders. Moreover, the present results suggest that the structure of the intron 2 region of the AP-2beta gene is one factor that contributes to development of the constitutional component of specific personality traits.

Background. Comparing stress levels in women entering IVF treatment with those of fertile controls as well as relating these levels to the outcome of IVF. Methods. State anxiety and personality profiles as well as stress hormones were studied in 22 normally menstruating women entering IVF treatment for tubal infertility. Their personality profiles as well as state anxiety scores measured before entering IVF treatment were related to the outcome of treatment. Twenty-two fertile women served as controls. Stress markers were serum prolactin and cortisol. These were estimated by radioimmunoassay. The psychological evaluation included the Karolinska Scales of Personality (KSP) and state anxiety as measured by the STAI questionnaire. Basal FSH on cycle day 3 and E2 and P4 AUC during the luteal phase were evaluated as hormonal predictors for the outcome of IVF treatment. Results. Comparison of the personality profiles of the two groups, showed that infertile women had significantly higher scores of suspicion (p>0.05), guilt (p>0.05), and hostility (p>0.01), but lower somatic anxiety (0.05) and indirect aggression (0.05) than fertile controls. The infertile women also had significantly higher levels of prolactin and cortisol throughout the menstrual cycle. Serum cortisol, prolactin and FSH levels on cycle day 3 did not differ between the women who conceived after IVF treatment and those who did not conceive. However, significant differences were found in E2 and P4 AUC (p>0.01) in the luteal phase between those women who became pregnant and those who failed. There was a trend (p

The study was part of the Jyvaskyla Longitudinal Study of Personality and Social Development, in which children's (196 boys, 173 girls) behavioral characteristics indicating the self-control of emotions were studied at age 8 using teacher ratings. At age 36, 140 men and 128 women filled in several inventories, including the Meta-Regulation Scale [Mayer, J. D., & Stevens, A. A. (1994). An emerging understanding of the reflective (meta-)experience of mood. Journal of Research in Personality , 28 , 351–373] and the Karolinska Scales of Personality [Af Klinteberg, B., Schalling, D., & Magnusson, D. (1986). Childhood behavior and adult personality in male and female subjects. European Journal of Personality , 4 , 57–71]. The study examined the relationships between the adults' emotion regulation strategies (ERS) of Repair, Maintenance and Dampening and concurrent personality characteristics. The question of the heterotypic continuity of the self-control of emotions, and of how the use of ERS might account for this was also examined. Correlational analysis, multivariate analysis of variance and path analysis showed, for men only, that low use of ERS relates to low self-control of emotions, whereas high use relates to high self-control. Moreover, the self-control of emotions showed heterotypic continuity over a period of 28 years, which can partly be explained by the mediating role of ERS. Individuals with low Repair had characteristics indicating low self-control of emotions at both ages. Conversely, individuals with high Repair showed high self-control of emotions at both ages. The somewhat different findings for women are discussed in relation to the literature on gender differences in emotionality and emotion regulation.

SummaryWith the purpose of comparing temperament traits in subjects who have been violent towards others and with subjects who have shown self-directed violence, 34 male suicide attempters and 34 male violent offenders were matched for age and psychiatric diagnosis. Violent offenders with a history of suicide attempts were excluded. Temperament traits were assessed by means of the Karolinska Scales of Personality.The temperament profiles of suicide attempters and violent offenders were very similar, with high trait anxiety and very low socialization. Violent offenders displayed significantly higher social desirability (P < 0.001). Suicide attempters tended to have higher indirect aggression and monotony avoidance. Impulsiveness, verbal aggression, and inhibition of aggression were within the normal range in both groups. There were substantial temperamental similarities between suicide attempters and violent offenders. In order to disentangle the differential mechanisms behind aggression towards self and others, we probably need to consider historical as well as current situation factors in a systematic way.

Human family and twin studies have established considerable heritable components in personality traits as assessed by self-report questionnaires. Recently, an association between a functional polymorphism in the upstream regulatory region of the serotonin transporter gene and neuroticism-related personality traits was reported. Two different serotonin transporter polymorphisms including the previously associated variant were genotyped in two samples of healthy Swedish subjects (n = 127 and n = 178, respectively) assessed with the Karolinska Scales of Personality (KSP) inventory. No statistically significant association between serotonin transporter polymorphisms and any of the eight neuroticism-related KSP scales was found. Thus, the previously reported association between serotonin transporter alleles and neuroticism-related personality traits could not be replicated in the present study.

BACKGROUND: Very few studies have compared the temperament traits in matched suicidal and non-suicidal patients with major depression. METHODS: We compared the temperament traits in two matched groups of patients with major depressive disorder (MDD), MDD with seasonal subtype (SAD) without any suicide attempt (n = 23) and MDD without seasonal variation who attempted suicide (non-SAD SA), and compared the patients to matched healthy controls by using the Karolinska Scales of Personality (KSP) and the Marke-Nyman Temperament (MNT) questionnaires. RESULTS: Both the SAD and non-SAD SA groups showed significantly higher Somatic Anxiety, Muscular Tension, Psychasthenia, Irritability, Suspicion, and lower Socialization and Validity than the controls. The non-SAD SA group also showed significantly higher Psychic Anxiety, Detachment and Guilt as compared to controls. When the SAD and the non-SAD SA were compared, we found significantly higher Somatic Anxiety, Psychic Anxiety and Muscular Tension for the non-SAD SA group. CONCLUSIONS: Both SAD and non-SAD SA patients display different temperament profiles compared to controls and in comparison with each other and the suicide attempters show especially high trait anxiety and hostility. CLINICAL RELEVANCE: The results suggest that trait anxiety and hostility, but not impulsivity, are associated with suicidal behavior in major depression. Language: en

The crux when contemplating neurosurgery for otherwise intractable mental illness is whether there is a price which the patient may have to pay, in terms of adverse personality changes, for symptom relief. In the present study of 19 patients undergoing thermo-capsulotomy for intractable obsessional illness, personality characteristics were studied pre-operatively, and at 1-year and 8-year follow-up, using the Karolinska Scales of Personality (KSP). Small mean score changes toward normalization were apparent on all 15 KSP scales at the 1-year follow-up, and significant improvements in anxiety proneness were noted at the 8-year follow-up. One patient who sustained a surgical complication showed deviant postoperative scores on scales related to psychopathic traits. There were no such deviant scores for the remaining subjects. The incidence of adverse personality changes following capsulotomy is low and does not increase with time. This conclusion, based on groups of patients, does not of course preclude the possibility that adverse personality changes may occur in individual patients.

Many genes have been identified that may play a role in increasing individual susceptibility to obesity. Reduced dopamine function appears to play a role in dysfunctional eating patterns and may predispose some individuals to obesity. The long version of the D4 dopamine receptor gene (D4DR) has been shown to alter receptor function and reduce intracellular response to dopamine. It also has been associated with novelty-seeking-related personality traits that are found with greater frequency in obese individuals. We examined the association between the long alleles of the D4DR and obesity in a sample of 115 obese patients participating in a weight management program. No direct relationship was found between the D4DR and body mass or novelty-seeking-related personality traits. We constructed four models of increased obesity risk that included combinations of traditional risk factors (i.e., long-term history of obesity, parental obesity, a body mass index > 40) and elevations on the novelty-seeking-related scales of the Karolinska Scales of Personality. There was a significant increase in the frequency of the D4DR long alleles in individuals defined as high risk using the combination of novelty-seeking-related personality traits, severe obesity (i.e., BMI > 40), and any other traditional risk factor, but not with the traditional risk factors alone. These preliminary data suggest a potential role for the D4DR gene in increasing obesity susceptibility.

Background: Decreased plasma levels of plasma-neuropeptide Y (NPY) and plasma-corticotropin releasing hormone (CRH), and increased levels of plasma delta-sleep inducing peptide (DSIP) in suicide attempters with mood disorders have previously been observed. This study was performed in order to further understand the clinical relevance of these findings. Methods: Examination of correlates between temperament dimensions (Karolinska Scales of Personality (KSP), the Eysenck Personality Questionnaire together with the IVE- impulsiveness scale (EPQI), and the Marke-Nyman Temperament (MNT)) and NPY, CRH and DSIP and serum-cortisol in the dexamethasone suppression test (DST) in 38 suicidal patients and matched controls. Results: NPY correlated significantly and positively with psychasthenia, irritability, and stability and significantly and negatively with validity in patients, but significantly and negatively with muscular tension, psychasthenia, verbal aggression and irritability in controls. DSIP correlated significantly and positively with impulsiveness (EPQI) in controls. CRH correlated negatively with lie in controls. Cortisol correlated significantly and positively with validity, extraversion and verbal aggression and significantly and negatively with inhibition of aggression in controls. Conclusion: NPY may be related to stress tolerance. DSIP seems to be associated with impulsivity/antisocial traits. Limitations: Non-suicidal patients were not included in the examination. Clinical Relevance: The state of depression or stress seems to influence the correlations studied.

The aim of the present study was to clarify the relationships between testosterone and alcohol abuse, alcohol dependence and specific personality characteristics and behaviors in a forensic psychiatric population. Serum levels of total testosterone (TT), free testosterone (FT-DPC) and sex hormone-binding globulin (SHBG) were determined in 61 male subjects undergoing forensic psychiatric examinations. All subjects had been detoxified from drugs and alcohol during previous incarceration in jail or hospital. TT and FT-DPC were found to be highly correlated (r=0.63, P < 0.0001). High concentrations of TT and SHBG were consistently related to type II alcoholism, but not pure alcohol dependence. TT and SHBG were also related to antisocial personality disorder. Furthermore, TT and SHBG were related to socially deviant behavior, reflected in factor 2 in the Psychopathy Checklist (PCL-R). In a multiple regression, FT-DPC was also clearly associated with the psychopathy-related scales of the Karolinska Scales of Personality (KSP) when age and signs of hepatic damage were kept under control.

Objective: To investigate stable personality traits in 73 patients with fibromyalgia [FMS] and compare the results with healthy controls, and patients with rheumatoid arthritis [RA].Methods: Personality traits were assessed by means of the Karolinska Scales of Personality.Results: Fibromyalgia patients had significantly higher scores on the scales for somatic anxiety, muscular tension, and psychasthenia compared to patients with RA and healthy controls. Scores for psychic anxiety was in the same range in both patient groups, and was significantly lower in FMS patients compared to normals. Despite the considerable variation, as concerns duration of illness in the FMS patients, only the psychasthenia scale correlated significantly with duration of illness.Conclusion: Fibromyalgia patients are characterized by high anxiety proneness associated with autonomic symptoms, difficulties in relaxing and easily fatigued. High scores in somatic anxiety and low psychic anxiety might indicate difficulties in relaxing a...

The study concerned possible mediators and moderators in the relationship between unemployment and psychological distress. The sample consisted of 58 unemployed and 177 employed 36-year-old Finnish people drawn from the ongoing Jyvaskyla Longitudinal Study of Personality and Social Development. Data were gathered by means of a mailed questionnaire, a semistructured interview, and personality inventories. The results showed that poor economic situation, and poor self-esteem as measured by Rosenberg's Self-Esteem Scale, mediated the relationship between unemployment and psychological distress even after controlling for the prior level of self-esteem. Psychological distress was defined as psychological ill-health (the General Health Questionnaire), depressive symptoms (the General Behavior Inventory), and anxiety (the Karolinska Scales of Personality). However, support was also found for an alternative model, in which depressive symptoms functioned as a mediator between long unemployment and poor self-esteem, suggesting that individuals may react to unemployment in different ways.

The aim of this study was to map the psychological/psychiatric, odontological and medical aspects of patients with symptoms allegedly related to the side-effects of mercury in dental fillings. A total of 67 consecutive patients and 64 controls matched for age, sex and residential area were included in the study. The most striking result was the high prevalence of psychiatric disorders in the patients (89%) compared to the controls (6%), predominantly somatoform disorders. The personality traits differentiating the patients according to the Karolinska Scales of Personality (KSP) were somatic anxiety, muscular tension, psychasthenia and low socialization. More patients than controls showed alexithymic traits. The prevalence of diagnosed somatic diseases was higher, but not sufficiently so to explain the large difference in perceived health. The multiple symptoms and signs of distress displayed by the patients could not be explained either by the odontological data or by the medical examination. Our data indicate that the patients show sociodemographic and clinical patterns similar to those of somatizing patients. The medicalization of the suffering of these patients and the neglect of psychiatric problems prevent the use of appropriate psychotherapeutic approaches.

Exciting and demanding biomedical experiments may attract a specific subgroup of people as volunteers. In the present study of selection bias, subjects volunteering in a psychobiological study that included a potentially painful procedure (lumbar puncture) were compared with those who declined to participate, with regard to scores on personality scales administered during a previous investigation of the same subjects. Significant differences were found on the Eysenck Personality Questionnaire and Karolinska Scales of Personality Impulsiveness scale, suggesting an over-representation of impulsive individuals among the volunteers. If the specific subject of investigation has implications for the type of individual who will participate as a healthy volunteer in biomedical research, variation will be introduced, affecting the independent variable, and the conclusions that can be drawn from such research may be questionable.

In the present study, personality traits, as assessed by the Karolinska Scales of Personality (KSP) were found to be stable after 9 years, both with regard to mean level stability (absolute stability) and rank-order stability (relative or differential stability). Moreover, outcome scales were applied measuring either perceptions of satisfaction or scales measuring functioning. Personality scales (from the Eysenck Personality Questionnaire and the KSP) completed in 1986/1987 were associated with measures (completed in 1995/1996) of satisfaction and functioning of family life, emotional and physical health, and work. Specifically, neuroticism-related personality traits predicted a lack of satisfaction with health, but not functional problems due to health. In contrast, neuroticism-related personality traits predicted poor functioning but not satisfaction with family life and work.

A population of 304 consecutive fire-setting offenders who had undergone a pre-trial forensic psychiatric evaluation in 1978–91 was traced in 1993 and asked to respond to a questionnaire concerning psychosocial outcome and receiving help. Of these, 264 were alive and a sample of 127 (48.1%) was reached. Of the 127 responders, 57 (44.9%) underwent an interview based on the Michigan Alcohol Screening Test (MAST) and 76 (59.8%) completed the Karolinska Scales of Personality (KSP). The criminal registry of Finland was searched for lifetime criminal offences at the end of 1993. Death certificates were examined to determine causes of death (N = 40). The distribution of psychiatric diagnoses among the responders, the deceased and the whole sample was similar. Recidivist fire-setters and violent offenders more often reported disappointment over not receiving psychosocial and medical help than once-only fire-setters. Recidivist offenders had lower socialization on the KSP than non-recidivist fire-setters....

Assessment of personality traits by means of the Karolinska Scales of Personality (KSP) was made in connection with a forensic psychiatric investigation and at follow-up after 2 years. For some subjects, major life events had occurred between the assessments - in some cases positive events such as marriage, having children, starting regular studies or employment, or receiving psychotherapeutic treatment. In many cases. however, the events or circumstances during the 2-year interval were negative, such as relapse in criminality, incarceration in prison for the whole period between the ratings, or development of a schizophrenic disorder. Moreover, the second assessments were performed in various settings. No significant differences between the two ratings were found in the traits Impulsiveness, Monotony avoidance, or Socialization. Measures of Indirect and Verbal aggression and Irritability also remained stable, as did measures of Guilt and Social desirability. Thus. KSP personality traits related to psycho...

In this study a behavior-genetic approach was used to identify sources of individual differences in Aggression-, Hostility- and Anger-related (AHA) personality traits (as measured with Spielberger's anger scales and scales from the Karolinska Scales of Personality), based on a sample (N = 140 individuals) that comprised of monozygotic twin pairs reared together (Npairs = 26) or reared apart (Npairs = 15), and dizygotic twin pairs reared together (Npairs = 29). In general, the results suggest that environmental factors account for sibling similarity in hostility, whereas genetic factors account for sibling similarity in angry aggression and irritability (trait anger).

As several studies have associated various temperament dimensions with suicidality when comparing suicide attempters with non-attempters, the purpose of the present study was to focus on the temperamental heterogeneity, and to identify sub-groups of suicide attempters with specific temperament profiles. The Karolinska Scales of Personality (KSP) and the Eysenck Personality Questionnaire together with the IVE-Impulsiveness scale (EPQ-I) were administered in a sample of 215 attempters aged 18–81 years, and cluster analysis procedures were performed with the KSP scales as clustering variables. The subjects were allocated into six mutually exclusive clusters with different temperament profiles. The EPQ-I was used in the attempts to validate and to further describe the cluster solution. Most of the clusters showed low Socialization scores and high scores on scales measuring trait Anxiety. We identified a sub-group with an extreme temperament profile scoring high on scales measuring trait Anxiety, Impulsiveness, Aggressivity, and on scales related to Psychoticism. We also identified an introverted and detached sub-group with high scores on Detachment (low Extraversion) and high trait Anxiety. A large sub-group showed no personality pathology in the sense that they had normal scores on all scales. Our results clearly indicate that suicide attempters are temperamentally heterogenous group, and that there are several different suicidal personalities. The temperamental heterogeneity of clinical importance and is worth further study.

Background: Although treatment failure after Vertical Banded Gastroplasty (VBG) is not uncommon, the safety of the procedure makes it the most widely used form of bariatric surgery. The reasons for failure may be either technical, such as staple-line dehiscence, or psychological inability on the part of the patient to adjust to the small stomach pouch and to its consequences. Methods: We carried out prospective testing of a cohort of consecutive VBG candidates, using a battery of psychological tests consisting of the ‘Three Factor Eating Questionnaire’, ‘Hopkins Symptom Check List (HSCL)’, ‘Mood Adjective Check List (MACL)’, ‘Karolinska Scales of Personality (KSP)’, and two projective tests, the ‘Meta-Contrast Technique (MCT)’ and the ‘Perceptgenetic Object Relation Test (PORT)’. The patients had been scheduled for surgery on clinical considerations only, and the results of the psychological testing were not disclosed to the surgeons until after the follow-up. Results: Mean preoperative Body Mass Index (BMI) was 42.0 (sd 9.9). Patients were extensively tested during the 3 weeks prior to surgery. There were no operative complications. Patients were tested psychologically again after 3 years. Their mean BMI then was 32.3 (sd 5.6). Thirteen patients had lost more than 50% of their overweight (BMI mean 29.6; sd 1.1), seven patients had lost less than 50% (BMI mean 37.0; sd 1.6; p = 0.0043). These two groups were compared. The single factor that correlated consistently with an unsatisfactory weight loss was preoperative signs of depression (p = 0.04). Stepwise discriminant analysis using three preoperative factors(Hunger, Verbal aggression and Socialization) correctly classified 90% of the patients who had lost

The relationships between, on the one hand, burnout, empathy and sense of cohoerence (SOC) and, on the other, personality traits were investigated, together with the effects of systematic clinical supervision on these phenomena among Swedish district nurses. The results in the supervisory group (n = 21) were compared with those of a comparison group (n = 12) in a quasi-experimental design. Personality traits were assessed by means of the Karolinska Scales of Personality. The results indicated some correlations between personality traits and burnout, empathy, and SOC, as well as correlations between the latter three phenomena. There were no significant effects of clinical supervision on burnout, empathy, or SOC. More research is needed regarding the effects of clinical nursing supervision.

This study analyses the relationships between scales from different personality questionnaires. Fifty normal young men answered a short form of The Minnesota Multiphasic Personality Inventory (MiniMult), the Karolinska Scales of Personality (KSP), the Eysenck Personality Inventory (EPI), and the Tridimensional Personality Questionnaire (TPQ). Relationships between these questionnaires were analyzed by Pearson bivariate correlations. These correlations pointed out several common aspects of basic personality dimensions as measured by the EPI or TPQ and confirmed that reliable relationships between similar scales from different personality questionnaires are found even in 50 normal subjects. Canonical correlations with anxiety and aggression factors extracted from the KSP and dimensions from the EPI and the TPQ showed that two basic dimensions, anxiety-neuroticism and aggression-extraversion, were found in all three questionnaires and that they remained independent. These results are in line with the theories considering personality as a paucidimensional process. With few exceptions, the dimensional approaches to personality (EPI, TPQ, KSP) and the clinically oriented categorical one (MiniMult) did not measure common aspects of the normal subjects' personality.

We previously reported that violent offenders with paranoid symptoms or whose violent actions had been directed against family members had higher urinary levels of bufotenin than other violent offenders. In the present study, patients were evaluated with the Karolinska Scales of Personality (KSP), and urinary levels of bufotenin were determined by mass spectrometry. In drug-free patients, suspiciousness was positively correlated, and socialization was negatively correlated, with urinary bufotenin excretion. These two personality variables were strongly interdependent. In drug users, bufotenin excretion was correlated positively with social desirability and negatively with irritability, but not with suspiciousness. Bufotenin excretion was not found to be associated with violence toward family members in the present study. The results are in keeping with the earlier finding that violent offenders with paranoid personality traits have higher urinary levels of bufotenin than other violent offenders.

The aim of this study was to explore and describe features of suicidal temperament and to describe the psychological domains of vulnerability in attempted suicide. Thirty-two suicide attempters were compared with 32 sex- and age-matched convalescent surgical controls on self-report personality inventories; the Eysenck Personality Questionnaire, the Chapman Scales, the Beck Hopelessnes Scale and the Karolinska Scales of Personality. Suicide attempters showed higher scale scores on neuroticism, psychoticism, interpersonal aversiveness, perceptual aberration, nonconformity, hopelessness, somatic anxiety, muscular tension, indirect aggression, suspicion and lower socialization. The features of suicidal temperament include hopelessness and anhedonia, anxiety, hostility and undirected anger expression, psychosis proneness, antisocial traits and interpersonal difficulties. These temperamental features might render the suicidal individual particularly vulnerable to suicidal behavior.

A consecutive series of 233 patients with persistent insomnia was studied with regard to personality traits by means of the Karolinska Scales of Personality (KSP). The group as a whole was found to have elevated scores on Psychasthenia, Muscular Tension, Somatic Anxiety, Psychic Anxiety, and Monotony Avoidance, and reduced scores on Socialization, Detachment, and Social Desirability. Patients with the subdiagnosis “psychophysiological insomnia” showed a relatively normal personality profile. Women over 50 years showed a special pattern with their most elevated score on Monotony Avoidance, and normal scores on Psychic and Somatic Anxiety. Analysis at the item level showed that, although Psychasthenia was the KSP scale that discriminated most strongly between insomniacs and controls, this does not indicate the presence of a genuinely psychasthenic personality; the insomniacs' elevated score on Psychasthenia was largely due to items that refer to typical symptoms of insomnia, like difficulty to regain lost sleep, fatigue, and concentration difficulties. The analysis suggested a number of possible factors that may be involved in the development of insomnia: self-imposed strain, excessive sensitivity, slow recuperation after stress, worrying, an overly serious attitude to life, negative family experiences, emotional over-involvement in others, dependence on others, and understimulation.

Psychologic factors were studied in 10 patients with symptoms presumed to be caused by electricity (EG) and in 10 patients with symptoms presumed to be caused by visual display units (VG) and compared with a sex- and age-matched control group (CG). Psychologic differences between the EG and VG were also measured. The symptoms presumed to be caused by electricity or visual display units were registered, and the personality, psychologic functioning, and quality of life were determined by using the Karolinska Scales of Personality (KSP), an additional Personality Scale (PS), a Psychological Functioning Scale (PFS), and a quality of Life Scale (QLS). The results showed that the commonest general symptoms in the EG/VG were skin complaints, fatigue, pain, and dizziness, and the commonest oral symptoms were gustatory disturbance, burning mouth, and temporomandibular joint dysfunction. The patients in the EG described more different types of both general and oral symptoms than those in the VG. The result showed that the VG scored significantly higher only in the KSP Somatic Anxiety and Muscular Tension scales, and the EG scored significantly lower in the KSP Socialization scale and significantly higher in the Somatic Anxiety, Muscular Tension, and Psychasthenia scales. In addition, only the EG differed significantly on the PS, PFS, and QLS. The EG differed significantly in such psychologic aspects as being more fatigued in the PS, in having more difficulty in concentrating, in taking the initiative, and in getting on with people in the PFS and experiencing inactivity and visiting other people rarely in the QLS. The conclusion was that patients with symptoms presumed to be caused by electricity and visual display units differed from each other psychologically and, therefore, should be handled clinically in different ways. The need for an interdisciplinary approach to these patients is emphasized.

Psychologic aspects of 49 patients with oral lichenoid reactions (OLR) in contact with amalgam fillings were studied and compared with an age- and sex-matched control group. Psychologic factors such as personality, psychologic functioning, and quality of life were determined by using the Karolinska Scales of Personality (KSP), an additional Personality Scale (PS), a Psychological Functioning Scale (PFS), and a Quality of Life Scale (QLS). With regard to personality the OLR patients had significantly higher scores on the muscular tension and suspicion scales and significantly lower scores on the indirect aggression scale. In addition, the OLR patients were significantly more worried about their health and more helpful. With regard to psychologic functioning the OLR patients had significantly more sad thoughts, became dizzy more easily, found it harder to imagine themselves free from anxiety, and had more difficulty in concentrating. The results indicated that OLR patients had a tendency to be depressive. The need for a systemic investigation including odontologic, medical, and psychologic aspects was expressed.

Twenty-five patients, 12 men and 13 women, aged 24-50 yr, who had consulted physicians and had received the diagnosis functional dyspepsia after extensive examination 6-8 years prior to this study, and were still suffering from this condition, were compared with community control subjects pair-wise matched for age and sex. Control subjects who had ever consulted a physician for gastrointestinal symptoms were excluded. Questionnaires measuring symptoms, job strain, social support and personality traits were used. Relatively few differences were found between groups. Compared to the community controls, however, the patients reported more gastrointestinal and nervous symptoms, and higher somatization, measured by Symptom Check List-90. The extent of reported overall distress was greater in patients than in control subjects. The detachment score (Karolinska Scales of Personality) was significantly lower in patients than in control subjects; this difference was also significant in separate analysis for men. Female patients had lower socialization and higher suspicion scores than female control subjects. Male patients reported more decision latitude (job control) than male control subjects.

Studies have shown that genetic components to some extent underlie behavioral disorders such as impulsive aggression and violence, and that central serotonergic mechanisms are involved in the development of such behavior. In the present study, we analyzed a polymorphism in the gene encoding the serotonin 2A receptor (5-HT2A -1438 G/A) in a group of Swedish criminals (n=97) and in a group of healthy Swedish blood donors (n=202). The 5-HT2A -1438 GG genotype was lower in the criminal group than in the control group (P=0.034). In accordance with previous results, no associations were found between the 5-HT2A -1438 G/A polymorphism and personality as measured by Karolinska Scales of Personality. Neither were there any associations between the studied polymorphism and the type of crime committed.

Background Previous studies indicate that maternal anxiety is associated with asthma in the adolescent child, but mechanisms are unclear. Objective To investigate the association between maternal anxiety and maternal, self- and register-based report of asthma in the adolescent child, and whether the association remains after control of familial confounding (shared environmental and genetic factors). Method From the Twin and Offspring Study of Sweden, 1691 mothers (1058 twins) and their adolescent child were included. The association between maternal self-reported anxiety (Beck Anxiety Inventory (BAI) and Karolinska Scales of Personality (KSP) somatic or psychic anxiety) and asthma based on subjective (maternal or child report) or objective (register-based diagnosis and medication) measures were analysed using logistic regression. The children-of-twins design was used to explore whether genes or environment contribute to the association. Results Maternal BAI anxiety (OR 2.02, CI 1.15–3.55) was significantly associated with adolescent asthma reported by the mother. Maternal KSP somatic anxiety (OR 1.74, CI 1.04–2.91) and psychic anxiety (OR 1.74, CI 1.05–2.86) was significantly associated with breathlessness reported by the adolescent child. In contrast, maternal anxiety was not associated with increased risk for the register-based outcomes of asthma diagnosis or medication. The results remained also after adjusting for covariates and the children-of-twins analyses which indicate that the association was due to familial confounding. Conclusions We found some associations between maternal anxiety and subjectively reported offspring asthma or breathlessness which may be due to familial effects. A likely candidate for explaining this familial confounding is heritable personality traits associated with both anxiety and subjective measures of asthma.

Continuity in individual differences from socioemotional behavior in middle childhood to personality characteristics in middle adulthood was examined on the assumption that they share certain temperament-related elements. Socioemotional characteristics were measured using teacher ratings at ages 8 (N = 369; 53% males) and 14 (95% of the initial sample). Personality was assessed at age 42 (63% of the initial sample; 50% males) using a shortened version of the NEO Personality Inventory (NEO-PI); the Karolinska Scales of Personality (KSP); and the Adult Temperament Questionnaire (ATQ). Three models were tested using structural equation modeling. The results confirmed paths (a) from behavioral activity to adult Extraversion and Openness (NEO-PI), sociability (KSP), and surgency (ATQ); (b) from well-controlled behavior to adult conformity (KSP) and Conscientiousness (NEO-PI); and (c) from negative emotionality to adult aggression (KSP). The paths were significant only for one gender, and more frequently for males than for females. The significant male paths from behavioral activity to all indicators of adult activity and from well-controlled behavior to adult conformity started at age 8, whereas significant female paths from behavioral activity to adult sociability and from well-controlled behavior to adult Conscientiousness started at age 14. peerReviewed

In earlier studies, the personality disorders in DSM-III-R have been demonstrated to be continous variables, thus describing personality traits with a range from normality to severe personality pathology instead of separate disorders with defined cut-off points. Thus, it seemed of interest to relate the personality disorders in the DSM-III-R to personality traits as determined by means of the Karolinska Scales of Personality (KSP). 144 patients with somatoform pain disorders orinsomia completed the study. In general the KSP scales Somatic anxiety, Psychic anxiety, Psychasthenia, Indirect aggression, Verbal aggression, Irritability and Suspicion gave significant positive correlations with all the personality disorders and the Clusters in the DSM-III-R. The scales Social desirability and Socialization gave significant negative correlations. In a stepwise regression the scales Socialization and Suspicion turned out to be of importance as concerns all three personality disorder Clusters.

Scores in 2 self-report personality questionnaires for 13 aggressive and 13 non-aggressive schizophrenic patients (AS and NAS) were compared to 13 healthy controls (HC), matched for age, and with similar educational background. The Eysenck Personality Questionnaire (EPQ, with 20 extra impulsiveness items yielding 114 items, 5 scales) and the Karolinska Scales of Personality (135 items, 15 subscales) were given. Premorbidly, the AS group had psychopathic as well as aggressive traits. The AS group perceived themselves as very similar to the HC group, in contrast to the NAS patients who seemed to be more aware of their problems. The most note-worthy finding was that the extremely aggressive and dangerous AS patients did not differ from the non-aggressive groups in terms of ratings of aggressiveness. The findings were interpreted as a lack of self-monitoring competency of the AS group, possibly related to other signs of frontal lobe dysfunction.

The object of the present survey was to examine whether the health conditions, social contacts, and personality traits of depressed patients were stable or had altered 12 months after their first admittance for depression. A cohort consisting of 31 first-admittance depressed patients from the catchment area of the Psychiatric Hospital in Aarhus were examined at admittance and 12 months later. The diagnostic assessment was carried out with the Present State Examination, 10th version; the social conditions were examined with a questionnaire on social class affiliation and selected living conditions, and the personality assessment was carried out using the questionnaire Karolinska Scales of Personality. The follow-up was carried out by mailing a letter with the two questionnaires exactly 12 months after admission. The examination yielded the following results: The presence of simultaneous anxiety appears to be quite constant. The patient group as such has become less isolated, but the total number of people ...

The NEO-PI–R has been one of the standard tools for measuring the Five Factor Model. Validity tests of the Swedish version of the NEO-PI-R have previously been limited to factor analyses and to testing the inventory's congruent validity using Hogan's Personality Inventory and the Karolinska Scales of Personality. The aim of the present study was to further investigate the validity of the NEO-PI–R. 53 pairs of volunteer college students who were peers (77 women, 29 men; M age = 27.3 yr., SD = 7) from the Department of Psychology at Stockholm University rated themselves both on the NEO-PI–R and on single statements taken from the NEO-PI–R Summary feedback sheet as well as rating their respective peers on a short version of the NEO-PI–R and on single statements taken from the NEO-PI–R Summary feedback sheet. The pattern of correlations indicated some support for the convergent and discriminant validity of the Swedish version of the NEO-PI–R.

The Karolinska Scales of Personality (KSP) is a self-rated personality inventory. The validity of an observer-rated version of the KSP in unknown.The aim of the study was to investigate how self-rated and observer-rated KSP scores related in a sample of severe obsessive-compulsive disorder (OCD) patients who had undergone neurosurgical treatment.The KSP was adapted for relatives by revising each item content where "I" was replaced by "NN", where "NN" was representing the relative's name. Eighteen patients and relatives completed the different versions of the KSP at a long-term visit following capsulotomy for OCD. Correlations and congruence between ratings and between KSP scores and symptom and adverse effect-ratings were calculated.There was no significant difference between the patient's own ratings and those of their relative's in 13 of the 15 KSP scales. The correlations ranged from 0.14 to 0.86 and were significant in 11 scales.The self-rated KSP can be used in an observer-rated version and is a relatively reliable instrument when compared with the self-rated version even in a sample of severely ill patients.