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Your search keyword '"Kengo Tokunaga"' showing total 66 results
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66 results on '"Kengo Tokunaga"'

51. A rare case of esophageal submucosal dissection thought to be caused by spontaneous intramural hematoma of the esophagus

Author

Shin'ichi Takahashi, Yasuharu Yamaguchi, Hirotaka Ohta, Kouichi Tabei, Yoko Jinbo, Tomohiko Hasue, Isamu Kurata, Mari Hayashida, Yasuo Ohkura, Kazunari Ochiai, Akiko Ohno, Masao Toki, Kazuhiko Hirano, Kengo Tokunaga, Hideyuki Hata, and Mitsunori Kusuhara

Subjects
medicine.medical_specialty, medicine.anatomical_structure, business.industry, Intramural hematoma, Mechanical Engineering, Rare case, medicine, Energy Engineering and Power Technology, Management Science and Operations Research, Esophagus, Submucosal dissection, business, Surgery
Published
2013
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52. [The antimicrobial susceptibility test of Helicobacter pylori]

Author

Shin'ichi, Takahashi, Kengo, Tokunaga, Akemi, Kai, Masao, Shingaki, and Takeshi, Itoh

Subjects
Helicobacter pylori, Drug Resistance, Bacterial, Microbial Sensitivity Tests
Abstract

Now that treatment of H. pylori associated disease is becoming common in Japan, drug resistant--H. pylori has emerged as a problem to be solved. There is no standard method of H. pylori drug susceptibility test in Japan yet. There are several methods available: Disk test, E-test, microplate method and agar plate dilution method. The E-test is being the standard method in European countries and USA. However the microplate method has been reported as a same accuracy as the agar dilution method, and thought as being a new standard method in Japan. In 2000, The Japanese Society of Chemotherapy proposed that drug susceptibility test be standardized and listed the break point of MIC of amoxicillin(AMPC) and clarithromycin(CAM).

Published
2003

53. Helicobacter pylori and acetylsalicylic acid synergistically accelerate apoptosis via Fas antigen pathway in rabbit gastric epithelial cells

Author

Kazuhiro, Watanabe, Satoshi, Hoshiya, Kengo, Tokunaga, Akifumi, Tanaka, Hidehiro, Watanabe, Shinya, Nagamatsu, Hitoshi, Ishida, and Shinichi, Takahashi

Subjects
Antigens, Bacterial, Aspirin, Helicobacter pylori, L-Lactate Dehydrogenase, Anti-Inflammatory Agents, Non-Steroidal, Immunoblotting, Apoptosis, DNA Fragmentation, Cell Line, Helicobacter Infections, Bacterial Proteins, Gastric Mucosa, Animals, Rabbits, fas Receptor
Abstract

The mechanism for gastric epithelial cellular apoptosis by both H. pylori and NSAIDs remains unknown. Normal gastric epithelial cells, collected from rabbit stomach, were cultured with viable H. pylori and/or an acetylsalicylic acid for 24 hr as an in vitro model of gastric epithelial cell injury. The Fas antigen expression rate in the gastric epithelial cells was measured using a FACScan. In group E, in which H. pylori inoculation of epithelial cells was followed by treatment with an NSAID, the rate of Fas antigen expression was significantly higher than the rate observed after treatment with either H. pylori or NSAID alone. Despite the fact that drug treatment alone did not significantly increase the Fas expression rate vs control cells. The results suggest that H. pylori and NSAID induce gastric cell injury as apoptosis via the Fas antigen pathway in a synergistic manner and that this effect is particularly strong when NSAID treatment follows H. pylori infection.

Published
2002

54. [Second line treatment regimen of PPI + AMPC + MNZ for patients with clarithromycin-resistant Helicobacter pylori infection]

Author

Kengo, Tokunaga and Shin-ichi, Takahashi

Subjects
Clinical Trials as Topic, Helicobacter pylori, Amoxicillin, Proton Pump Inhibitors, 2-Pyridinylmethylsulfinylbenzimidazoles, Drug Administration Schedule, Helicobacter Infections, Clarithromycin, Metronidazole, Rabeprazole, Drug Resistance, Bacterial, Humans, Benzimidazoles, Drug Therapy, Combination, Treatment Failure, Enzyme Inhibitors, Omeprazole
Published
2002

55. Relationship Between Endoscopic Findings and H.pylori Infection

Author

Junichi Uematsu, Shin'ichi Takahashi, Takuji Gotoda, Takashi Kawai, Fuminori Moriyasu, Masakatsu Fukuzawa, Kengo Tokunaga, and Masatake Sato

Subjects
medicine.medical_specialty, Hepatology, business.industry, Internal medicine, Gastroenterology, medicine, H pylori infection, business
Published
2014
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60. Lactobacillus reuteri Tablets Can Suppress Helicobacter pylori Infection

Author

Kyoto Imase, Hajime Sugano, Shinʼichi Takahashi, Akifumi Tanaka, and Kengo Tokunaga

Subjects
Cross over, Helicobacter pylori infection, medicine.medical_specialty, Hepatology, biology, business.industry, Gastroenterology, biology.organism_classification, Placebo, Lactobacillus reuteri, Double blind, Clinical study, Internal medicine, Medicine, business
Published
2005
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63. Corrigendum

Author

Tatsuhiro Masaoka, Yo Kawamura, Takeshi Matsuhisa, Takashi Kawai, Shin Ichi Takahashi, Masayoshi Ito, Hidekazu Suzuki, Tetsuya Mine, Nobuhiro Sakaki, Masayuki Suzuki, and Kengo Tokunaga

Subjects
Helicobacter pylori infection, medicine.medical_specialty, biology, business.industry, Gastroenterology, General Medicine, Japanese population, biology.organism_classification, Metropolitan area, Microbiology, Second line drug, Metronidazole, Infectious Diseases, Multicenter study, Internal medicine, medicine, Helicobacter, business, medicine.drug
Published
2006
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64. Urgent evolution of amoxicillin resistant strains of Helicobacter pylori in Japan (1985–2000)

Author

Akifumi Tanaka, Takeshi Itoh, Hitoshi Ishida, Kazuhiro Watanabe, Kiyoto Imase, Shin'ichi Takahashi, Hajime Sugano, Satoshi Hoshiya, Shingaki Akemi Kai, and Kengo Tokunaga

Subjects
Hepatology, biology, business.industry, Gastroenterology, medicine, Amoxicillin, Helicobacter pylori, biology.organism_classification, business, medicine.drug, Microbiology
Published
2001
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65. No correlation between the appearance of mucosal lesions after the cure of Helicobacter pylori infection and the gastrin, pepsinogen, secretin levels. A two-years follow up study in Japan

Author

Kazuhiro Watanabe, Akifumi Tanaka, Kengo Tokunaga, Hitoshi Ishida, Kiyoto Imase, Hajime Sugano, Shin'ichi Takahashi, and Satoshi Hoshiya

Subjects
medicine.medical_specialty, Helicobacter pylori infection, Hepatology, biology, business.industry, Mucosal lesions, Gastroenterology, Follow up studies, Secretin, Pepsin, Internal medicine, biology.protein, Medicine, business, Gastrin
Published
2000
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66. Evolution of Helicobacter pylori antibiotic resistance in Japan (1985–1997)

Author

Satoru Takahashi, Satoshi Hoshiya, Akifumi Tanaka, S. Saito, H. Ninomiya, Kazuhiro Watanabe, N. Nakamura, Kengo Tokunaga, N. Masubuchi, M. Shingaki, and Takeshi Itoh

Subjects
Antibiotic resistance, Hepatology, biology, business.industry, Gastroenterology, Medicine, Helicobacter pylori, business, biology.organism_classification, Microbiology
Published
1998
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