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51. Racial and Ethnic Bias in Letters of Recommendation and Personal Statements for Application to Otolaryngology Residency

Author

Stack, Taylor J., primary, Berk, Garrett A., additional, Ho, Tiffany D., additional, Zeatoun, Abdullah, additional, Kong, Keonho A., additional, Chaskes, Mark B., additional, Thorp, Brian D., additional, Ebert Jr., Charles S., additional, DeMason, Christine E., additional, Senior, Brent A., additional, and Kimple, Adam J., additional

Published
2023
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55. The next step: Replacing step 1 as a metric for residency application

Author

Berk, Garrett A., primary, Ho, Tiffany D., additional, Stack‐Pyle, Taylor J., additional, Zeatoun, Abdullah, additional, Kong, Keonho A., additional, Chaskes, Mark B., additional, Thorp, Brian D., additional, Ebert, Charles S., additional, DeMason, Christine E., additional, Kimple, Adam J., additional, and Senior, Brent A., additional

Published
2022
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58. The management of cystic fibrosis chronic rhinosinusitis:An evidenced-based review with recommendations

Author

Spielman, Daniel B., Beswick, Daniel M., Kimple, Adam J., Senior, Brent A., Aanaes, Kasper, Woodworth, Bradford A., Schlosser, Rodney J., Lee, Stella, Cho, Do Yeon, Adappa, Nithin D., DiMango, Emily, Gudis, David A., Spielman, Daniel B., Beswick, Daniel M., Kimple, Adam J., Senior, Brent A., Aanaes, Kasper, Woodworth, Bradford A., Schlosser, Rodney J., Lee, Stella, Cho, Do Yeon, Adappa, Nithin D., DiMango, Emily, and Gudis, David A.

Abstract

Background: Cystic fibrosis (CF) chronic rhinosinusitis (CRS) has emerged as a distinct diagnostic entity, unique from other endotypes of CRS in its presentation, pathophysiology, diagnosis, treatment, and outcomes. As the sinonasal health of this patient population may have broad effects on pulmonary health and quality of life, a comprehensive understanding of the diagnostic and therapeutic approach to CF CRS is essential. In recognizing recent scientific advances and unique treatment modalities specific to this challenging patient population, in this review we systematically evaluate the scientific literature and provide an evidenced-based review with recommendations (EBRR) for fundamental management principles of CF CRS. Methods: A systematic review of the literature was performed. Studies evaluating interventions for the management of CF CRS were included. An iterative review process was implemented in accordance with EBRR guidelines. A treatment recommendation was generated based on an assessment of the benefits, harms, and the overall grade of evidence. Results: We evaluated the published literature on 5 unique topics. Each of the following therapeutic categories was investigated explicitly for treatment outcomes in patients with CF CRS: (1) nasal saline; (2) intranasal corticosteroids (INCS); (3) topical antibiotics; (4) cystic fibrosis transmembrane conductance regulator (CFTR) modulator therapy; and (5) endoscopic sinus surgery (ESS). Conclusion: Based on the currently available evidence, nasal saline, ESS, and CFTR modulators are recommended in the management of CF CRS when appropriate. INCS and topical antibiotics are options. Clinical judgment and experience are essential in caring for patients with this uniquely challenging disorder.

Published
2022

61. A longitudinal study of olfactory dysfunction and parosmia in mild COVID-19 cases

Author

Ebert, Charles S., Wohl, David, Onuorah, Princess, Kimple, Adam J., Murr, Alexander, Bacon, Daniel R., Thorp, Brian D., Monk, Aurelia S., Senior, Brent A., Oakes, Jonathan, and Wiesen, Christopher A.

Subjects
Article
Abstract

Background: COVID-19-related olfactory dysfunction (OD) can persist long after patients recover from acute infection, yet few studies have investigated the long-term progression of this complication. Moreover, existing studies are focused on hyposmia/anosmia but parosmia is becoming an increasingly recognized long-term symptom. Methods: We completed a longitudinal study about OD in individuals with mild cases of COVID-19. Participants completed a questionnaire and Brief Smell Identification Test (BSIT) one week, one month and one year after diagnosis. At one-year, participants completed an additional survey about parosmia. Results: We obtained questionnaires and psychophysical olfactory testing information from participants at one week (n=45), one month (n=38), and one year (n=33) post COVID-19 diagnosis. At one-year, 15.2% of participants had persistent OD and 66.7% of participants reported experiencing parosmia at some point following COVID-19 diagnosis. The mean onset of parosmia was 1.3 weeks (SD: 1.9 weeks) after diagnosis, although two patients reported delayed onset (>4 weeks after diagnosis). Eight patients (24.2%) reported ongoing parosmia one year after diagnosis. Of the patients whose parosmia resolved, the mean duration of symptoms was 7.2 weeks (SD: 7.3 weeks). Conclusion: Decreased sense of smell associated with COVID-19 infection has received significant recognition in both the media and in the medical literature. Symptoms of OD and parosmia were common in our patients with COVID-19. Hyposmia, anosmia, and parosmia, all decrease quality of life, necessitating continued research to understand the pathogenesis, course of symptoms, and possible treatment for these complications.

Published
2022

62. Pharmacokinetic-based failure of a detergent virucidal for severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) nasal infections: A preclinical study and randomized controlled trial

Author

Esther, Charles R., Huang, Li Ching, Edwards, Caitlin E., Pickles, Raymond J., Baric, Ralph S., Kimple, Adam J., Kimura, Kyle S., Randell, Scott H., Freeman, Michael H., Wessinger, Bronson C., Von Wahlde, Kate, Strickland, Britton A., Turner, Justin H., Mikami, Yu, Boucher, Richard C., Kato, Takafumi, Bacon, Daniel R., Gupta, Veerain C., Sheng, Quanhu, Das, Suman R., Ceppe, Agathe S., and Brown, Hunter M.

Abstract

BACKGROUND: The nose is the portal for severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) infection, suggesting the nose as a target for topical antiviral therapies. The purpose of this study was to assess both the in vivo and in vitro efficacy of a detergent-based virucidal agent, Johnson and Johnson's Baby Shampoo (J&J), in SARS-CoV-2-infected subjects. METHODS: Subjects were randomized into three treatment groups: (1) twice daily nasal irrigation with J&J in hypertonic saline, (2) hypertonic saline alone, and (3) no intervention. Complementary in vitro experiments were performed in cultured human nasal epithelia. The primary outcome measure in the clinical trial was change in SARS-CoV-2 viral load over 21 days. Secondary outcomes included symptom scores and change in daily temperature. Outcome measures for in vitro studies included change in viral titers. RESULTS: Seventy-two subjects completed the clinical study (n = 24 per group). Despite demonstrated safety and robust efficacy in in vitro virucidal assays, J&J irrigations had no impact on viral titers or symptom scores in treated subjects relative to controls. Similar findings were observed administering J&J to infected cultured human airway epithelia using protocols mimicking the clinical trial regimen. Additional studies of cultured human nasal epithelia demonstrated that lack of efficacy reflected pharmacokinetic failure, with the most virucidal J&J detergent components rapidly absorbed from nasal surfaces. CONCLUSION: In this randomized clinical trial of subjects with SARS-CoV-2 infection, a topical detergent-based virucidal agent had no effect on viral load or symptom scores. Complementary in vitro studies confirmed a lack of efficacy, reflective of pharmacokinetic failure and rapid absorption from nasal surfaces.

Published
2022
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66. Cystic Fibrosis Foundation otolaryngology care multidisciplinary consensus recommendations

Author

Kimple, Adam J., primary, Senior, Brent A., additional, Naureckas, Edward T., additional, Gudis, David A., additional, Meyer, Ted, additional, Hempstead, Sarah E., additional, Resnick, Helaine E., additional, Albon, Dana, additional, Barfield, Wayne, additional, Benoit, Margo McKenna, additional, Beswick, Daniel M., additional, Callard, Eliza, additional, Cofer, Shelagh, additional, Downer, Veronica, additional, Elson, E. Claire, additional, Garinis, Angela, additional, Halderman, Ashleigh, additional, Hamburger, Lisa, additional, Helmick, Meagan, additional, McCown, Michael, additional, McKinzie, Cameron J., additional, Phan, Hanna, additional, Rodriguez, Kenneth, additional, Rubenstein, Ronald C., additional, Severin, Ashley, additional, Shah, Gopi, additional, Shenoy, Ambika, additional, Sprouse, Brittney, additional, Virgin, Frank, additional, Woodworth, Bradford A., additional, and Lee, Stella E., additional

Published
2022
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68. A Review of Popular Nasal Irrigation Systems

Author

Berk, Garrett A., additional, Zeatoun, Abdullah, additional, Kong, Keonho A., additional, Chaskes, Mark B., additional, Senior, Brent A., additional, Ebert, Charles S., additional, and Kimple, Adam J., additional

Published
2022
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72. Pharmacokinetic‐based failure of a detergent virucidal for severe acute respiratory syndrome–coronavirus‐2 (SARS‐CoV‐2) nasal infections: A preclinical study and randomized controlled trial

Author

Esther, Charles R., primary, Kimura, Kyle S., additional, Mikami, Yu, additional, Edwards, Caitlin E., additional, Das, Suman R., additional, Freeman, Michael H., additional, Strickland, Britton A., additional, Brown, Hunter M., additional, Wessinger, Bronson C., additional, Gupta, Veerain C., additional, Von Wahlde, Kate, additional, Sheng, Quanhu, additional, Huang, Li Ching, additional, Bacon, Daniel R., additional, Kimple, Adam J., additional, Ceppe, Agathe S., additional, Kato, Takafumi, additional, Pickles, Raymond J., additional, Randell, Scott H., additional, Baric, Ralph S., additional, Turner, Justin H., additional, and Boucher, Richard C., additional

Published
2022
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73. The management of cystic fibrosis chronic rhinosinusitis: An evidenced‐based review with recommendations

Author

Spielman, Daniel B., primary, Beswick, Daniel M., additional, Kimple, Adam J., additional, Senior, Brent A., additional, Aanaes, Kasper, additional, Woodworth, Bradford A., additional, Schlosser, Rodney J., additional, Lee, Stella, additional, Cho, Do‐Yeon, additional, Adappa, Nithin D., additional, DiMango, Emily, additional, and Gudis, David A., additional

Published
2022
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76. Outcomes in Pediatric Endoscopic Skull Base Surgery: A Systematic Review.

Author

Lopez, Erin M., Farzal, Zainab, Dean, Kelly M., Miller, Craig, Morse, Justin C., Ebert Jr., Charles S., Kimple, Adam J., Thorp, Brian D., and Zanation, Adam M.

Subjects
SKULL base, SKULL surgery, CEREBROSPINAL fluid leak, PEDIATRIC surgery, TERTIARY care, CHILD patients
Abstract

Objectives The frequency of endoscopic skull base surgery in pediatric patients is increasing. This study aims to systematically review the literature for endoscopic skull base surgery outcomes in children/adolescents aged 0 to 18 years. Design A systematic review of the literature was performed in PubMed and SCOPUS databases querying studies from 2000 to 2020 using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Final inclusion criteria included: case series with more than 10 patients with pediatric patients aged ≤18 years, endoscopic or endoscopic-assisted skull base surgery, and outcomes reported. Setting This study was conducted at a tertiary care medical center. Participants Children/adolescents aged 0 to 18 years who underwent endoscopic skull base surgery were participated in this study. Main Outcome Measures Patient demographics, pathology, reconstructive technique, intraoperative findings, intraoperative, and postoperative surgical complications were measured through this study. Results Systematic literature search yielded 287 publications. Of these, 12 studies discussing a total of 399 patients aged 0 to 18 years met inclusion criteria for final analysis. Seven of the 12 studies discussed a single pathology. The most common pathology was a skull base defect causing cerebrospinal fluid (CSF) leak. The majority of skull base repairs were made with free tissue grafts. The most common postoperative complication was CSF leak (n = 40). Twelve cases of meningitis occurred postoperatively with two of these episodes resulting in death. Conclusion Endoscopic skull base surgery has been performed recently in the pediatric population in a variety of disease states. Inconsistent individual-level data and reporting standards are present in existing studies posing challenges for comparative analysis. Standardized reporting will aid future reviews and meta-analysis for rare skull base pathology. [ABSTRACT FROM AUTHOR]

Published
2023
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79. Robust W1282X-CFTR rescue by a small molecule GSPT1 degrader

Author

Lee, Rhianna E., primary, Lewis, Catherine A., additional, He, Lihua, additional, Gallant, Samuel C., additional, Mascenik, Teresa M., additional, Dang, Hong, additional, Morton, Lisa C., additional, Minges, John T., additional, Theile, Jonathan W., additional, Castle, Neil A., additional, Knowles, Michael R., additional, Kimple, Adam J., additional, and Randell, Scott H., additional

Published
2021
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85. Pharmacokinetic-based failure of a detergent virucidal for SARS-COV-2 nasal infections

Author

Esther, Charles R., primary, Kimura, Kyle S., additional, Mikami, Yu, additional, Edwards, Caitlin E., additional, Das, Suman R., additional, Freeman, Michael H., additional, Strickland, Britton A., additional, Brown, Hunter M., additional, Wessinger, Bronson C., additional, Gupta, Veerain C., additional, Von Wahlde, Kate, additional, Sheng, Quanhu, additional, Huang, Li Ching, additional, Bacon, Daniel R., additional, Kimple, Adam J., additional, Ceppe, Agathe S., additional, Kato, Takafumi, additional, Pickles, Raymond J., additional, Randell, Scott H., additional, Baric, Ralph S., additional, Turner, Justin H., additional, and Boucher, Richard C., additional

Published
2021
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87. Postoperative Pain Management and Perceived Patient Outcomes following Endoscopic Pituitary Surgery.

Author

Hoke, Austin T.K., Malfitano, Madison, Zanation, Adam M., Ebert Jr., Charles S., Senior, Brent A., Kimple, Adam J., and Thorp, Brian D.

Subjects
POSTOPERATIVE pain treatment, ENDOSCOPIC surgery, MEDICAL prescriptions, RHINORRHEA, OPIOID epidemic, ELECTRONIC health records, OPIOID analgesics
Abstract

Objectives  Pain management remains a point of emphasis given the ongoing opioid crisis. There are no studies in the literature interrogating opioid prescribing and use following endoscopic pituitary surgery. This study investigates provider prescribing tendency, patient utilization of analgesics, and patient outcomes regarding pain management after endoscopic pituitary surgery. Methods  We identified 100 patients undergoing endoscopic pituitary surgery at one institution from 2016 to 2018 in the electronic medical record (EMR) and state narcotic database to determine postoperative analgesic regimens. A telephone survey was used to characterize postoperative analgesic use and satisfaction with prescribed regimen. Results  Fifty-two different pain control regimens were prescribed to the study patients. Also, 93% of study patients were prescribed an opioid postoperatively. The average quantity of opioids prescribed per patient in morphine milligram equivalents (MMEs) was 625 (equivalent 83 oxycodone 5-mg tablets) with an average MME/day of 59 (equivalent 8 oxycodone 5-mg tablets). A total of 71% survey respondents who used opioids reported using <25% of their prescription. The majority of prescription narcotic users consumed >50% of their postoperative opioid intake in the first 24 to 48 hours after discharge. There were no significant differences in pain outcome between opioid users and nonopioid users. Conclusion  Vast heterogeneity exists in narcotic prescribing by providers at our institution following endoscopic pituitary surgery. Narcotic prescribing patterns exceeded most patients' analgesic needs. Opioid analgesics were not superior to nonopioids regimens in patient-reported pain outcomes in this study population. [ABSTRACT FROM AUTHOR]

Published
2022
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88. Structural diversity in the RGS domain and its interaction with heterotrimeric G protein [alpha]-subunits

Author

Soundararajan, Meera, Willard, Francis S., Kimple, Adam J., Turnbull, Andrew P., Ball, Linda J., Schoch, Guillaume A., Gileadi, Carina, Fedorov, Oleg Y., Dowler, Elizabeth F., Higman, Victoria A., Hutsell, Stephanie Q., Sundstrom, Michael, Doyle, Declan A., and Siderovski, David P.

Subjects
G proteins -- Properties, G proteins -- Control, G proteins -- Structure, Guanosine triphosphatase -- Properties, Nuclear magnetic resonance -- Methods, X-ray crystallography -- Methods, Science and technology
Abstract

Regulator of G protein signaling (RGS) proteins accelerate GTP hydrolysis by G[alpha] subunits and thus facilitate termination of signaling initiated by G protein-coupled receptors (GPCRs). RGS proteins hold great promise as disease intervention points, given their signature role as negative regulators of GPCRs--receptors to which the largest fraction of approved medications are currently directed. RGS proteins share a hallmark RGS domain that interacts most avidly with G[alpha] when in its transition state for GTP hydrolysis; by binding and stabilizing switch regions I and II of G[alpha], RGS domain binding consequently accelerates G[alpha]-mediated GTP hydrolysis. The human genome encodes more than three dozen RGS domain-containing proteins with varied G[alpha] substrate specificities. To facilitate their exploitation as drug-discovery targets, we have taken a systematic structural biology approach toward cataloging the structural diversity present among RGS domains and identifying molecular determinants of their differential G[alpha] selectivities. Here, we determined 14 structures derived from NMR and x-ray crystallography of members of the R4, R7, R12, and RZ subfamilies of RGS proteins, including 10 uncomplexed RGS domains and 4 RGS domain/G[alpha] complexes. Heterogeneity observed in the structural architecture of the RGS domain, as well as in engagement of switch Ill and the all-helical domain of the G[alpha] substrate, suggests that unique structural determinants specific to particular RGS protein/G[alpha] pairings exist and could be used to achieve selective inhibition by small molecules. GTPase-accelerating proteins | NMR structure | RGS proteins | x-ray crystallography

Published
2008

89. Understood? Evaluating the readability and understandability of intranasal corticosteroid delivery instructions Intranasal Steroid Readability/Understandability

Author

Lee, Saangyoung E., Brown, William C., Gelpi, Mark W., Kimple, Adam J., Senior, Brent A., Zanation, Adam M., Thorp, Brian D., and Ebert, Charles S.

Subjects
Adrenal Cortex Hormones, Humans, Comprehension, Article, Administration, Intranasal, Drug Labeling, Health Literacy
Abstract

BACKGROUND: Allergic rhinitis is a widespread disease that has significant quality-of-life ramifications. Symptoms include rhinorrhea, nasal obstruction, cough, and post-nasal drip. Intranasal corticosteroids are a hallmark of treatment of allergic rhinitis. However, the benefits of treatment are dependent on correct nasal spray technique of which many patients are not aware. Patient instructions are included with the purchase of these medications. The readability and understandability for these educational materials has been minimally assessed in the medical literature. The aim of this study is to evaluate the readability and understandability of commonly used intranasal steroids. METHODS: Three readability measures (Gunning Fog, Simple Measure of Gobbledygook (SMOG), and FORCAST) and an understandability assessment (Patient Education Materials Assessment Tool for Printable Materials (PEMAT-P)) were used to evaluate the instructions for use of commonly prescribed intranasal steroids. Instructions with 6(th) grade readability level or lower were considered to meet health literacy experts’ recommendations. Higher understandability values correlate to easier understandability. RESULTS: Instructions for ten intranasal corticosteroid brands were reviewed. Gunning Fog consistently estimated easiest readability, whereas FORCAST most difficult. 20% of analyzed instructions met National Institutes of Health and health literacy experts’ recommended reading levels. Understandability of instructions ranged from 33% to 90%, with an average of 66%. CONCLUSION: The benefit of intranasal corticosteroids is contingent on correct use by patients. However, the pre-packaged instructions provided are most often above recommended reading levels and are difficult to understand. Future development of intranasal steroid instructions should meet recommended readability levels and be understandable to maximize their utility.

Published
2020

93. Rab7a in Endocytosis and Signaling

Author

Martemyanov, Kirill A., primary, Parameswaran, Pooja, additional, Aligianis, Irene, additional, Handley, Mark, additional, Gual-Soler, Marga, additional, Taguchi, Tomohiko, additional, Stow, Jennifer L., additional, Wicking, Carol, additional, BasuRay, Soumik, additional, Agola, Jacob O., additional, Jim, Patricia A., additional, Seaman, Matthew N., additional, Wandinger-Ness, Angela, additional, Ward, Heather H., additional, Konstantinidis, Diamantis, additional, Kalfa, Theodosia A., additional, Varga, Andrea, additional, Baccarini, Manuela, additional, Hay, Debbie L., additional, Sexton, Patrick M., additional, Poyner, David R., additional, Petosa, Carlo, additional, Nakashima, Tomoki, additional, Takayanagi, Hiroshi, additional, Nguyen, Hoa B., additional, Quilliam, Lawrence A., additional, Samuel, Michael S., additional, Lapinski, Philip E., additional, King, Philip D., additional, Santos, Eugenio, additional, Fernández-Medarde, Alberto, additional, Priatel, John J., additional, Tsai, Kevin, additional, Harder, Kenneth W., additional, González de Aguilar, Jose-Luis, additional, Philippov, Pavel P., additional, Zernii, Evgeni Yu, additional, Fujiwara, Masakazu, additional, Ghazizadeh, Mohammad, additional, Summers, Roger J., additional, Halls, Michelle L., additional, Westhuizen, Emma T., additional, Busby, Scott A., additional, Burris, Thomas P., additional, Siderovski, David P., additional, Kimple, Adam J., additional, Xie, Zhihui, additional, Druey, Kirk M., additional, Reymond, Nicolas, additional, Vega, Francisco M., additional, Ridley, Anne J., additional, Tall, Gregory G., additional, Cai, Weikang, additional, Rudolph, Jennifer L., additional, Andres, Douglas A., additional, Colicelli, John, additional, Ting, Pamela Y., additional, Janson, Christine, additional, Olson, Michael F., additional, Brody, James P., additional, Maupin-Furlow, Julie A., additional, Miranda, Hugo V., additional, Roux, Philippe P., additional, Van Petegem, Filip, additional, and Lau, Kelvin, additional

Published
2012
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94. Ras Associated with Diabetes

Author

Martemyanov, Kirill A., primary, Parameswaran, Pooja, additional, Aligianis, Irene, additional, Handley, Mark, additional, Gual-Soler, Marga, additional, Taguchi, Tomohiko, additional, Stow, Jennifer L., additional, Wicking, Carol, additional, BasuRay, Soumik, additional, Agola, Jacob O., additional, Jim, Patricia A., additional, Seaman, Matthew N., additional, Wandinger-Ness, Angela, additional, Ward, Heather H., additional, Konstantinidis, Diamantis, additional, Kalfa, Theodosia A., additional, Varga, Andrea, additional, Baccarini, Manuela, additional, Hay, Debbie L., additional, Sexton, Patrick M., additional, Poyner, David R., additional, Petosa, Carlo, additional, Nakashima, Tomoki, additional, Takayanagi, Hiroshi, additional, Nguyen, Hoa B., additional, Quilliam, Lawrence A., additional, Samuel, Michael S., additional, Lapinski, Philip E., additional, King, Philip D., additional, Santos, Eugenio, additional, Fernández-Medarde, Alberto, additional, Priatel, John J., additional, Tsai, Kevin, additional, Harder, Kenneth W., additional, González de Aguilar, Jose-Luis, additional, Philippov, Pavel P., additional, Zernii, Evgeni Yu, additional, Fujiwara, Masakazu, additional, Ghazizadeh, Mohammad, additional, Summers, Roger J., additional, Halls, Michelle L., additional, Westhuizen, Emma T., additional, Busby, Scott A., additional, Burris, Thomas P., additional, Siderovski, David P., additional, Kimple, Adam J., additional, Xie, Zhihui, additional, Druey, Kirk M., additional, Reymond, Nicolas, additional, Vega, Francisco M., additional, Ridley, Anne J., additional, Tall, Gregory G., additional, Cai, Weikang, additional, Rudolph, Jennifer L., additional, Andres, Douglas A., additional, Colicelli, John, additional, Ting, Pamela Y., additional, Janson, Christine, additional, Olson, Michael F., additional, Brody, James P., additional, Maupin-Furlow, Julie A., additional, Miranda, Hugo V., additional, Roux, Philippe P., additional, Van Petegem, Filip, additional, and Lau, Kelvin, additional

Published
2012
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95. RARα

Author

Martemyanov, Kirill A., primary, Parameswaran, Pooja, additional, Aligianis, Irene, additional, Handley, Mark, additional, Gual-Soler, Marga, additional, Taguchi, Tomohiko, additional, Stow, Jennifer L., additional, Wicking, Carol, additional, BasuRay, Soumik, additional, Agola, Jacob O., additional, Jim, Patricia A., additional, Seaman, Matthew N., additional, Wandinger-Ness, Angela, additional, Ward, Heather H., additional, Konstantinidis, Diamantis, additional, Kalfa, Theodosia A., additional, Varga, Andrea, additional, Baccarini, Manuela, additional, Hay, Debbie L., additional, Sexton, Patrick M., additional, Poyner, David R., additional, Petosa, Carlo, additional, Nakashima, Tomoki, additional, Takayanagi, Hiroshi, additional, Nguyen, Hoa B., additional, Quilliam, Lawrence A., additional, Samuel, Michael S., additional, Lapinski, Philip E., additional, King, Philip D., additional, Santos, Eugenio, additional, Fernández-Medarde, Alberto, additional, Priatel, John J., additional, Tsai, Kevin, additional, Harder, Kenneth W., additional, González de Aguilar, Jose-Luis, additional, Philippov, Pavel P., additional, Zernii, Evgeni Yu, additional, Fujiwara, Masakazu, additional, Ghazizadeh, Mohammad, additional, Summers, Roger J., additional, Halls, Michelle L., additional, Westhuizen, Emma T., additional, Busby, Scott A., additional, Burris, Thomas P., additional, Siderovski, David P., additional, Kimple, Adam J., additional, Xie, Zhihui, additional, Druey, Kirk M., additional, Reymond, Nicolas, additional, Vega, Francisco M., additional, Ridley, Anne J., additional, Tall, Gregory G., additional, Cai, Weikang, additional, Rudolph, Jennifer L., additional, Andres, Douglas A., additional, Colicelli, John, additional, Ting, Pamela Y., additional, Janson, Christine, additional, Olson, Michael F., additional, Brody, James P., additional, Maupin-Furlow, Julie A., additional, Miranda, Hugo V., additional, Roux, Philippe P., additional, Van Petegem, Filip, additional, and Lau, Kelvin, additional

Published
2012
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96. Relaxin Family Peptide Receptors (RXFP) 3 and 4

Author

Martemyanov, Kirill A., primary, Parameswaran, Pooja, additional, Aligianis, Irene, additional, Handley, Mark, additional, Gual-Soler, Marga, additional, Taguchi, Tomohiko, additional, Stow, Jennifer L., additional, Wicking, Carol, additional, BasuRay, Soumik, additional, Agola, Jacob O., additional, Jim, Patricia A., additional, Seaman, Matthew N., additional, Wandinger-Ness, Angela, additional, Ward, Heather H., additional, Konstantinidis, Diamantis, additional, Kalfa, Theodosia A., additional, Varga, Andrea, additional, Baccarini, Manuela, additional, Hay, Debbie L., additional, Sexton, Patrick M., additional, Poyner, David R., additional, Petosa, Carlo, additional, Nakashima, Tomoki, additional, Takayanagi, Hiroshi, additional, Nguyen, Hoa B., additional, Quilliam, Lawrence A., additional, Samuel, Michael S., additional, Lapinski, Philip E., additional, King, Philip D., additional, Santos, Eugenio, additional, Fernández-Medarde, Alberto, additional, Priatel, John J., additional, Tsai, Kevin, additional, Harder, Kenneth W., additional, González de Aguilar, Jose-Luis, additional, Philippov, Pavel P., additional, Zernii, Evgeni Yu, additional, Fujiwara, Masakazu, additional, Ghazizadeh, Mohammad, additional, Summers, Roger J., additional, Halls, Michelle L., additional, Westhuizen, Emma T., additional, Busby, Scott A., additional, Burris, Thomas P., additional, Siderovski, David P., additional, Kimple, Adam J., additional, Xie, Zhihui, additional, Druey, Kirk M., additional, Reymond, Nicolas, additional, Vega, Francisco M., additional, Ridley, Anne J., additional, Tall, Gregory G., additional, Cai, Weikang, additional, Rudolph, Jennifer L., additional, Andres, Douglas A., additional, Colicelli, John, additional, Ting, Pamela Y., additional, Janson, Christine, additional, Olson, Michael F., additional, Brody, James P., additional, Maupin-Furlow, Julie A., additional, Miranda, Hugo V., additional, Roux, Philippe P., additional, Van Petegem, Filip, additional, and Lau, Kelvin, additional

Published
2012
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97. RAB23, Member RAS Oncogene Family

Author

Martemyanov, Kirill A., primary, Parameswaran, Pooja, additional, Aligianis, Irene, additional, Handley, Mark, additional, Gual-Soler, Marga, additional, Taguchi, Tomohiko, additional, Stow, Jennifer L., additional, Wicking, Carol, additional, BasuRay, Soumik, additional, Agola, Jacob O., additional, Jim, Patricia A., additional, Seaman, Matthew N., additional, Wandinger-Ness, Angela, additional, Ward, Heather H., additional, Konstantinidis, Diamantis, additional, Kalfa, Theodosia A., additional, Varga, Andrea, additional, Baccarini, Manuela, additional, Hay, Debbie L., additional, Sexton, Patrick M., additional, Poyner, David R., additional, Petosa, Carlo, additional, Nakashima, Tomoki, additional, Takayanagi, Hiroshi, additional, Nguyen, Hoa B., additional, Quilliam, Lawrence A., additional, Samuel, Michael S., additional, Lapinski, Philip E., additional, King, Philip D., additional, Santos, Eugenio, additional, Fernández-Medarde, Alberto, additional, Priatel, John J., additional, Tsai, Kevin, additional, Harder, Kenneth W., additional, González de Aguilar, Jose-Luis, additional, Philippov, Pavel P., additional, Zernii, Evgeni Yu, additional, Fujiwara, Masakazu, additional, Ghazizadeh, Mohammad, additional, Summers, Roger J., additional, Halls, Michelle L., additional, Westhuizen, Emma T., additional, Busby, Scott A., additional, Burris, Thomas P., additional, Siderovski, David P., additional, Kimple, Adam J., additional, Xie, Zhihui, additional, Druey, Kirk M., additional, Reymond, Nicolas, additional, Vega, Francisco M., additional, Ridley, Anne J., additional, Tall, Gregory G., additional, Cai, Weikang, additional, Rudolph, Jennifer L., additional, Andres, Douglas A., additional, Colicelli, John, additional, Ting, Pamela Y., additional, Janson, Christine, additional, Olson, Michael F., additional, Brody, James P., additional, Maupin-Furlow, Julie A., additional, Miranda, Hugo V., additional, Roux, Philippe P., additional, Van Petegem, Filip, additional, and Lau, Kelvin, additional

Published
2012
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98. Ras-Associated Protein RAB8

Author

Martemyanov, Kirill A., primary, Parameswaran, Pooja, additional, Aligianis, Irene, additional, Handley, Mark, additional, Gual-Soler, Marga, additional, Taguchi, Tomohiko, additional, Stow, Jennifer L., additional, Wicking, Carol, additional, BasuRay, Soumik, additional, Agola, Jacob O., additional, Jim, Patricia A., additional, Seaman, Matthew N., additional, Wandinger-Ness, Angela, additional, Ward, Heather H., additional, Konstantinidis, Diamantis, additional, Kalfa, Theodosia A., additional, Varga, Andrea, additional, Baccarini, Manuela, additional, Hay, Debbie L., additional, Sexton, Patrick M., additional, Poyner, David R., additional, Petosa, Carlo, additional, Nakashima, Tomoki, additional, Takayanagi, Hiroshi, additional, Nguyen, Hoa B., additional, Quilliam, Lawrence A., additional, Samuel, Michael S., additional, Lapinski, Philip E., additional, King, Philip D., additional, Santos, Eugenio, additional, Fernández-Medarde, Alberto, additional, Priatel, John J., additional, Tsai, Kevin, additional, Harder, Kenneth W., additional, González de Aguilar, Jose-Luis, additional, Philippov, Pavel P., additional, Zernii, Evgeni Yu, additional, Fujiwara, Masakazu, additional, Ghazizadeh, Mohammad, additional, Summers, Roger J., additional, Halls, Michelle L., additional, Westhuizen, Emma T., additional, Busby, Scott A., additional, Burris, Thomas P., additional, Siderovski, David P., additional, Kimple, Adam J., additional, Xie, Zhihui, additional, Druey, Kirk M., additional, Reymond, Nicolas, additional, Vega, Francisco M., additional, Ridley, Anne J., additional, Tall, Gregory G., additional, Cai, Weikang, additional, Rudolph, Jennifer L., additional, Andres, Douglas A., additional, Colicelli, John, additional, Ting, Pamela Y., additional, Janson, Christine, additional, Olson, Michael F., additional, Brody, James P., additional, Maupin-Furlow, Julie A., additional, Miranda, Hugo V., additional, Roux, Philippe P., additional, Van Petegem, Filip, additional, and Lau, Kelvin, additional

Published
2012
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99. ROCK: ROK kinase

Author

Martemyanov, Kirill A., primary, Parameswaran, Pooja, additional, Aligianis, Irene, additional, Handley, Mark, additional, Gual-Soler, Marga, additional, Taguchi, Tomohiko, additional, Stow, Jennifer L., additional, Wicking, Carol, additional, BasuRay, Soumik, additional, Agola, Jacob O., additional, Jim, Patricia A., additional, Seaman, Matthew N., additional, Wandinger-Ness, Angela, additional, Ward, Heather H., additional, Konstantinidis, Diamantis, additional, Kalfa, Theodosia A., additional, Varga, Andrea, additional, Baccarini, Manuela, additional, Hay, Debbie L., additional, Sexton, Patrick M., additional, Poyner, David R., additional, Petosa, Carlo, additional, Nakashima, Tomoki, additional, Takayanagi, Hiroshi, additional, Nguyen, Hoa B., additional, Quilliam, Lawrence A., additional, Samuel, Michael S., additional, Lapinski, Philip E., additional, King, Philip D., additional, Santos, Eugenio, additional, Fernández-Medarde, Alberto, additional, Priatel, John J., additional, Tsai, Kevin, additional, Harder, Kenneth W., additional, González de Aguilar, Jose-Luis, additional, Philippov, Pavel P., additional, Zernii, Evgeni Yu, additional, Fujiwara, Masakazu, additional, Ghazizadeh, Mohammad, additional, Summers, Roger J., additional, Halls, Michelle L., additional, Westhuizen, Emma T., additional, Busby, Scott A., additional, Burris, Thomas P., additional, Siderovski, David P., additional, Kimple, Adam J., additional, Xie, Zhihui, additional, Druey, Kirk M., additional, Reymond, Nicolas, additional, Vega, Francisco M., additional, Ridley, Anne J., additional, Tall, Gregory G., additional, Cai, Weikang, additional, Rudolph, Jennifer L., additional, Andres, Douglas A., additional, Colicelli, John, additional, Ting, Pamela Y., additional, Janson, Christine, additional, Olson, Michael F., additional, Brody, James P., additional, Maupin-Furlow, Julie A., additional, Miranda, Hugo V., additional, Roux, Philippe P., additional, Van Petegem, Filip, additional, and Lau, Kelvin, additional

Published
2012
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100. Rho-Associated Kinase

Author

Martemyanov, Kirill A., primary, Parameswaran, Pooja, additional, Aligianis, Irene, additional, Handley, Mark, additional, Gual-Soler, Marga, additional, Taguchi, Tomohiko, additional, Stow, Jennifer L., additional, Wicking, Carol, additional, BasuRay, Soumik, additional, Agola, Jacob O., additional, Jim, Patricia A., additional, Seaman, Matthew N., additional, Wandinger-Ness, Angela, additional, Ward, Heather H., additional, Konstantinidis, Diamantis, additional, Kalfa, Theodosia A., additional, Varga, Andrea, additional, Baccarini, Manuela, additional, Hay, Debbie L., additional, Sexton, Patrick M., additional, Poyner, David R., additional, Petosa, Carlo, additional, Nakashima, Tomoki, additional, Takayanagi, Hiroshi, additional, Nguyen, Hoa B., additional, Quilliam, Lawrence A., additional, Samuel, Michael S., additional, Lapinski, Philip E., additional, King, Philip D., additional, Santos, Eugenio, additional, Fernández-Medarde, Alberto, additional, Priatel, John J., additional, Tsai, Kevin, additional, Harder, Kenneth W., additional, González de Aguilar, Jose-Luis, additional, Philippov, Pavel P., additional, Zernii, Evgeni Yu, additional, Fujiwara, Masakazu, additional, Ghazizadeh, Mohammad, additional, Summers, Roger J., additional, Halls, Michelle L., additional, Westhuizen, Emma T., additional, Busby, Scott A., additional, Burris, Thomas P., additional, Siderovski, David P., additional, Kimple, Adam J., additional, Xie, Zhihui, additional, Druey, Kirk M., additional, Reymond, Nicolas, additional, Vega, Francisco M., additional, Ridley, Anne J., additional, Tall, Gregory G., additional, Cai, Weikang, additional, Rudolph, Jennifer L., additional, Andres, Douglas A., additional, Colicelli, John, additional, Ting, Pamela Y., additional, Janson, Christine, additional, Olson, Michael F., additional, Brody, James P., additional, Maupin-Furlow, Julie A., additional, Miranda, Hugo V., additional, Roux, Philippe P., additional, Van Petegem, Filip, additional, and Lau, Kelvin, additional

Published
2012
Full Text
View/download PDF

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