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The number of peripheral eosinophils was counted in female Swiss albino mice on 1, 4, 9, 16 and 30 days after infection with various single (500, 1000 and 2000) and weekly repeated (500 + + 500 + 1000, 1000 + 1000 and 1000 + 1000 + 2000) doses of filariform Ancylostoma caninum larvae. The eosinophil response was significantly higher in infected than in uninfected mice and reached a peak on day 16 in naive and day 4 and 9 in immunized mice. Immunized mice were significantly more eosinophilic than the naive mice. An attempt has been made to correlate eosinophilia with immunity of mice to A. caninum larvae.