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456 results on '"Kozobolis, Vassilios"'

76. Corneal melting after collagen cross-linking for keratoconus: a case report

Author

Zissimopoulos Athanassios, Koukoula Stavrenia, Kaloghianni Eleni, Labiris Georgios, and Kozobolis Vassilios P

Subjects
Medicine
Abstract

Abstract Introduction Corneal collagen cross-linking is a rather new technique that uses riboflavin and ultraviolet A light for collagen fiber stabilization in keratoconus corneas. Other than reversible side effects, the preliminary results of corneal collagen cross-linking studies suggest that it is a rather safe technique. In this report, we demonstrate a case of corneal melting after corneal collagen cross-linking for keratoconus corneas associated with an acute inflammatory response. Case presentation A 23-year-old Caucasian man with keratoconus cornea stage 1 to 2 underwent uneventful corneal collagen cross-linking treatment according to the Dresden protocol. The next day the patient had intense photophobia, watering and redness of the eye, and his visual acuity was limited to counting fingers. Slit lamp biomicroscopy revealed severe corneal haze accompanied by non-specific endothelial precipitates following an acute inflammatory response. Mild inflammation could be detected in the anterior chamber. Moreover, the re-epithelialization process could barely be detected. His corneal state gradually deteriorated, resulting in descemetocele and finally perforation. Conclusion In this report, we present a case of a patient with corneal melting after standard corneal collagen cross-linking treatment for keratoconus corneas following an acute inflammatory response. Despite modifying postoperative treatment, elaboration of all apparent associated causes by the treating physicians and undergoing extensive laboratory testing, the patient developed descemetocele, which led to perforation. Our report suggests that further research is necessary regarding the safety of corneal collagen cross-linking in keratoconus corneas.

Published
2011
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78. Additional file 1: of Impact of polyethylene glycol 400/propylene glycol/hydroxypropyl-guar and 0.1% sodium hyaluronate on postoperative discomfort following cataract extraction surgery: a comparative study

Author

Labiris, Georgios, Ntonti, Panagiota, Sideroudi, Haris, and Kozobolis, Vassilios

Subjects
body regions, genetic structures, nervous system, fungi, eye diseases
Abstract

Post-Cataract subjective discomfort index questionnaire (Cat-SDI-Q) ver.1.1. (PDF 75.2 kb)

Published
2017
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79. The Effect of Corneal Refractive Surgery on Glaucoma

Author

Kozobolis, Vassilios, Konstantinidis, Aristeidis, Sideroudi, Haris, and Labiris, G.

Subjects
genetic structures, Article Subject, sense organs, eye diseases
Abstract

Laser-assisted refractive procedures have become very popular in the last two decades. As a result, a “generation” of patients with altered corneal properties is emerging. These patients will require both cataract extraction and glaucoma follow-up in the future. Since the glaucoma examination largely depends on the corneal properties, the reshaped postrefractive surgery cornea poses a challenge in the diagnosis, follow-up, and management of the glaucomatous patient. In order to overcome this problem, every patient who is planned to undergo corneal refractive surgery must have a thorough glaucoma examination in order for the ophthalmologist to be able to monitor their patients for possible glaucoma development and/or progression. Some examinations such as tonometry are largely affected by the corneal properties, while others such as the evaluation of the structures of the posterior pole remain unaffected. However, the new imaging modalities of the anterior segment in combination with the most recent advances in tonometry can accurately assess the risk for glaucoma and the need for treatment.

Published
2017
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88. Ranibizumab for the treatment of degenerative ocular conditions

Author

Panos, George, Triantafylla,Magdalini, Massa,Horace F., Dardabounis,Doukas, Gatzioufas,Zisis, Kozobolis,Vassilios, Ioannakis,Konstantinos, and Perente,Ä°rfan

Subjects
genetic structures, Clinical Ophthalmology
Abstract

Magdalini Triantafylla,1 Horace F Massa,2 Doukas Dardabounis,1 Zisis Gatzioufas,2 Vassilios Kozobolis,1 Konstantinos Ioannakis,1 Irfan Perente,1,3 Georgios D Panos1,21Department of Ophthalmology, University General Hospital of Alexandroupolis, School of Medicine, University of Thrace, Alexandroupolis, Greece; 2Department of Ophthalmology, Geneva University Hospitals, Faculty of Medicine, University of Geneva, Switzerland; 3Beyoglou Eye Research and Teaching Hospital, Istanbul University, Istanbul, TurkeyAbstract: Degenerative ocular conditions, such as age-related macular degeneration, diabetic retinopathy, retinal vein occlusions, and myopic degeneration, have become a major public health problem and a leading cause of blindness in developed countries. Anti-vascular endothelial growth factor (VEGF) drugs seem to be an effective and safe treatment for these conditions. Ranibizumab, a humanized monoclonal antibody antigen-binding fragment, which inhibits all biologically active isoforms of VEGF-A, is still the gold standard treatment for the majority of these pathological entities. In this review, we present the results of the most important clinical trials concerning the efficacy and safety of ranibizumab for the treatment of degenerative ocular conditions.Keywords: age-related macular degeneration, diabetic macular edema, retinal vein occlusion, anti-VEGF, safety, efficacy, quality of life

Published
2014

91. Effect of Riboflavin/UVA Collagen Cross-linking on Central Cornea, Limbus and Intraocular Pressure. Experimental Study in Rabbit Eyes

Author

Kozobolis, Vassilios, primary, Gkika, Maria, additional, Sideroudi, Haris, additional, Tsaragli, Efthymia, additional, Lydataki, Stylliani, additional, Naoumidi, Irini, additional, Giatromanolaki, Alexandra, additional, Mikropoulos, Dimitrios, additional, Teus, Miguel, additional, and Labiris, Georgios, additional

Published
2016
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