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1,151 results on '"Lee, Kyung-Hun"'

52. PP048 Replication stress contributes to activation of the DNA damage response and lapatinib resistance in HER2-amplified SK-BR-3 cells

Author

Kim, So Hyeon, primary, Min, Ahrum, additional, Kim, Seongyeong, additional, Kim, Yu-Jin, additional, Ham, Sujin, additional, Lee, Minyoung, additional, Hwang, Hae Min, additional, Lee, Changyun, additional, Kim, Jinyong, additional, Lee, Dae-Won, additional, Lee, Kyung-Hun, additional, and Im, Seock-Ah, additional

Published
2023
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53. OP02-1 Safety and efficacy of eribulin in patients with advanced or metastatic breast cancer previously treated with anthracycline and taxane in real-world clinical practice: Data from post-marketing surveillance in Korea

Author

Chae, Yee Soo, primary, Kwon, Kyung A., additional, Lee, Moon Hee, additional, Ahn, Mi Sun, additional, Lee, Kyung-Hun, additional, Koh, Su-Jin, additional, Sohn, Joohyuk, additional, Park, Keon Uk, additional, Kim, Min Young, additional, Pyo, Youngji, additional, Kim, Bo Young, additional, and Jung, Kyung Hae, additional

Published
2023
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57. Survival with nal-IRI (liposomal irinotecan) plus 5-fluorouracil and leucovorin versus 5-fluorouracil and leucovorin in per-protocol and non-per-protocol populations of NAPOLI-1: Expanded analysis of a global phase 3 trial

Author

Chen, Li-Tzong, Siveke, Jens T., Wang-Gillam, Andrea, Li, Chung-Pin, Bodoky, György, Dean, Andrew P., Shan, Yan-Shen, Jameson, Gayle S., Macarulla, Teresa, Lee, Kyung-Hun, Cunningham, David, Blanc, Jean-Frédéric, Chiu, Chang-Fang, Schwartsmann, Gilberto, Braiteh, Fadi S., Mamlouk, Khalid, Belanger, Bruce, de Jong, Floris A., and Hubner, Richard A.

Published
2018
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58. Fulvestrant plus goserelin versus anastrozole plus goserelin versus goserelin alone for hormone receptor-positive, HER2-negative tamoxifen-pretreated premenopausal women with recurrent or metastatic breast cancer (KCSG BR10-04): a multicentre, open-label, three-arm, randomised phase II trial (FLAG study)

Author

Kim, Ji-Yeon, Im, Seock-Ah, Jung, Kyung Hae, Ro, Jungsil, Sohn, Joohyuk, Kim, Jee Hyun, Park, Yeon Hee, Kim, Tae-Yong, Kim, Sung-Bae, Lee, Keun Seok, Kim, Gun Min, Kim, Se Hyun, Kim, Seonwoo, Ahn, Jin Seok, Lee, Kyung-Hun, Ahn, Jin-Hee, Park, In Hae, and Im, Young-Hyuck

Published
2018
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68. Differences in severity of chemotherapy-induced nausea and vomiting between neoadjuvant and adjuvant chemotherapy in patients with breast cancer: Analysis of data from two prospective observational studies

Author

Son, Kyung-Lak, primary, Shin, Joon Sung, additional, Lee, Sun Hyung, additional, Lee, Sungwon, additional, Jung, Saim, additional, Kim, Won-Hyoung, additional, Jung, Dooyoung, additional, Kim, Tae-Yong, additional, Im, Seock-Ah, additional, Lee, Kyung-Hun, additional, Hahm, Bong-Jin, additional, and Yeom, Chan-Woo, additional

Published
2023
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70. Circulating Tumor DNA Dynamics and Treatment Outcome of Regorafenib in Metastatic Colorectal Cancer

Author

Lee, Dae-Won, primary, Lim, Yoojoo, additional, Kim, Hwang-Phill, additional, Kim, Su Yeon, additional, Roh, Hanseong, additional, Kang, Jun-Kyu, additional, Lee, Kyung‑Hun, additional, Kim, Min Jung, additional, Ryoo, Seung-Bum, additional, Park, Ji Won, additional, Jeong, Seung-Yong, additional, Park, Kyu Joo, additional, Kang, Gyeong Hoon, additional, Han, Sae-Won, additional, and Kim, Tae-You, additional

Published
2023
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71. Phase II, multicentre, randomised trial of eribulin plus gemcitabine versus paclitaxel plus gemcitabine as first-line chemotherapy in patients with HER2-negative metastatic breast cancer

Author

Park, Yeon Hee, Im, Seock-Ah, Kim, Sung-Bae, Sohn, Joo Hyuk, Lee, Keun Seok, Chae, Yee Soo, Lee, Ki Hyeong, Kim, Jee Hyun, Im, Young-Hyuck, Kim, Ji-Yeon, Kim, Tae-Yong, Lee, Kyung-Hun, Ahn, Jin-Hee, Kim, Gun Min, Park, In Hae, Lee, Soo Jung, Han, Hye Sook, Kim, Se Hyun, and Jung, Kyung Hae

Published
2017
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75. Integrated Design of Hydraulic Coupling Bolts for Large Shaft Systems.

Author

Park, Sung-Cheol, Lee, In-Kyu, Lee, Sang-Kon, and Lee, Kyung-Hun

Subjects
HYDRAULIC couplings, FINITE element method, STRUCTURAL reliability, STRESS concentration, STRENGTH of materials, BOLTED joints
Abstract

Hydraulic coupling bolts are used in a wide range of industrial sectors, where ensuring the structural integrity and reliability of shaft systems is of paramount importance. However, research on systematic design methods for these specialized bolts is still lacking. In this study, an integrated design was used on hydraulic coupling bolts with M72 specification, considering both the tightening and untightening processes. First, the second tightening load was determined based on material strength, stress concentration and safety factors. Subsequently, the upper and lower limits of the first tightening loads were calculated using the thick-walled cylinder theory. An appropriate first tightening load maintaining the tightening force in both the axial and radial directions was obtained using finite element analysis. Design variables for the adapter configuration and oil passage shape were selected, and their impact on structural integrity was assessed using finite element analysis. The optimal combination of these design variables was derived. Finally, operational experiments for hydraulic coupling bolts were conducted according to the design results. The test results demonstrated a successful tightening and untightening process, confirming the effectiveness of the proposed design method. [ABSTRACT FROM AUTHOR]

Published
2024
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79. Mutational evolution after chemotherapy‐progression in metastatic colorectal cancer revealed by circulating tumor DNA analysis

Author

Kim, Sheehyun, primary, Cha, Yongjun, additional, Lim, Yoojoo, additional, Roh, Hanseong, additional, Kang, Jun‐Kyu, additional, Lee, Kyung‐Hun, additional, Kim, Min Jung, additional, Park, Ji Won, additional, Ryoo, Seung‐Bum, additional, Kim, Hwang‐Phill, additional, Jeong, Seung‐Yong, additional, Park, Kyu Joo, additional, Han, Sae‐Won, additional, and Kim, Tae‐You, additional

Published
2023
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80. Changes in the severity of chemotherapy-induced nausea and vomiting according to the menopausal stage of breast cancer patients during adjuvant chemotherapy: A prospective observational study

Author

Yeom, Chan-Woo, primary, Lee, Sangil, additional, Lee, Seonmi, additional, Son, Kyung-Lak, additional, Lee, Kwang-Min, additional, Kim, Won-Hyoung, additional, Kim, Tae-Yong, additional, Im, Seock-Ah, additional, Lee, Kyung-Hun, additional, Hahm, Bong-Jin, additional, and Jung, Dooyoung, additional

Published
2023
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82. Abstract LB228: Replication stress activates the DNA damage response and contributes to lapatinib resistance in HER2-positive SK-BR-3 cells

Author

Kim, So Hyeon, primary, Min, Ahrum, additional, Kim, Seongyeong, additional, Kim, Yu Jin, additional, Ham, Sujin, additional, Hwang, Hae Min, additional, Lee, Minyoung, additional, Lee, Changyun, additional, Kim, Jinyong, additional, Lee, Dae-Won, additional, Lee, Kyung-Hun, additional, and Im, Seock-Ah, additional

Published
2023
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84. Supplementary Figure S4 from AZD6738, A Novel Oral Inhibitor of ATR, Induces Synthetic Lethality with ATM Deficiency in Gastric Cancer Cells

Author

Min, Ahrum, primary, Im, Seock-Ah, primary, Jang, Hyemin, primary, Kim, Seongyeong, primary, Lee, Miso, primary, Kim, Debora Keunyoung, primary, Yang, Yaewon, primary, Kim, Hee-Jun, primary, Lee, Kyung-Hun, primary, Kim, Jin Won, primary, Kim, Tae-Yong, primary, Oh, Do-Youn, primary, Brown, Jeff, primary, Lau, Alan, primary, O'Connor, Mark J., primary, and Bang, Yung-Jue, primary

Published
2023
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85. Supplementary Figures 1 - 9, Tables 1 - 2 from RAD51C-Deficient Cancer Cells Are Highly Sensitive to the PARP Inhibitor Olaparib

Author

Min, Ahrum, primary, Im, Seock-Ah, primary, Yoon, Young-Kwang, primary, Song, Sang-Hyun, primary, Nam, Hyun-Jin, primary, Hur, Hyung-Seok, primary, Kim, Hwang-Phill, primary, Lee, Kyung-Hun, primary, Han, Sae-Won, primary, Oh, Do-Youn, primary, Kim, Tae-You, primary, O'Connor, Mark J., primary, Kim, Woo-Ho, primary, and Bang, Yung-Jue, primary

Published
2023
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86. Data from Src as a Therapeutic Target in Biliary Tract Cancer

Author

Nam, Ah-Rong, primary, Kim, Ji-Won, primary, Park, Ji Eun, primary, Bang, Ju-Hee, primary, Jin, Mei Hua, primary, Lee, Kyung-Hun, primary, Kim, Tae-Yong, primary, Han, Sae-Won, primary, Im, Seock-Ah, primary, Kim, Tae-You, primary, Oh, Do-Youn, primary, and Bang, Yung-Jue, primary

Published
2023
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89. Conflict of Interest Form from AZD6738, A Novel Oral Inhibitor of ATR, Induces Synthetic Lethality with ATM Deficiency in Gastric Cancer Cells

Author

Min, Ahrum, primary, Im, Seock-Ah, primary, Jang, Hyemin, primary, Kim, Seongyeong, primary, Lee, Miso, primary, Kim, Debora Keunyoung, primary, Yang, Yaewon, primary, Kim, Hee-Jun, primary, Lee, Kyung-Hun, primary, Kim, Jin Won, primary, Kim, Tae-Yong, primary, Oh, Do-Youn, primary, Brown, Jeff, primary, Lau, Alan, primary, O'Connor, Mark J., primary, and Bang, Yung-Jue, primary

Published
2023
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90. Supplementary Figure Legends from AZD6738, A Novel Oral Inhibitor of ATR, Induces Synthetic Lethality with ATM Deficiency in Gastric Cancer Cells

Author

Min, Ahrum, primary, Im, Seock-Ah, primary, Jang, Hyemin, primary, Kim, Seongyeong, primary, Lee, Miso, primary, Kim, Debora Keunyoung, primary, Yang, Yaewon, primary, Kim, Hee-Jun, primary, Lee, Kyung-Hun, primary, Kim, Jin Won, primary, Kim, Tae-Yong, primary, Oh, Do-Youn, primary, Brown, Jeff, primary, Lau, Alan, primary, O'Connor, Mark J., primary, and Bang, Yung-Jue, primary

Published
2023
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92. Supplementary Figure Legend from RAD51C-Deficient Cancer Cells Are Highly Sensitive to the PARP Inhibitor Olaparib

Author

Min, Ahrum, primary, Im, Seock-Ah, primary, Yoon, Young-Kwang, primary, Song, Sang-Hyun, primary, Nam, Hyun-Jin, primary, Hur, Hyung-Seok, primary, Kim, Hwang-Phill, primary, Lee, Kyung-Hun, primary, Han, Sae-Won, primary, Oh, Do-Youn, primary, Kim, Tae-You, primary, O'Connor, Mark J., primary, Kim, Woo-Ho, primary, and Bang, Yung-Jue, primary

Published
2023
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93. Supplementary Table S1 from AZD6738, A Novel Oral Inhibitor of ATR, Induces Synthetic Lethality with ATM Deficiency in Gastric Cancer Cells

Author

Min, Ahrum, primary, Im, Seock-Ah, primary, Jang, Hyemin, primary, Kim, Seongyeong, primary, Lee, Miso, primary, Kim, Debora Keunyoung, primary, Yang, Yaewon, primary, Kim, Hee-Jun, primary, Lee, Kyung-Hun, primary, Kim, Jin Won, primary, Kim, Tae-Yong, primary, Oh, Do-Youn, primary, Brown, Jeff, primary, Lau, Alan, primary, O'Connor, Mark J., primary, and Bang, Yung-Jue, primary

Published
2023
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95. Nanoliposomal irinotecan with fluorouracil and folinic acid in metastatic pancreatic cancer after previous gemcitabine-based therapy (NAPOLI-1): a global, randomised, open-label, phase 3 trial

Author

Adoo, Clarence, Anderson, Thomas, Asselah, Jamil, Azambuja, Alan, Bampton, Carolyn, Barrios, Carlos Henrique, Bekaii-Saab, Tanios, Bohuslav, Melichar, Chang, David, Chen, Jen-Shi, Chen, Yeu-Chin, Choi, Hye Jin, Chung, Ik Joo, Chung, Vincent, Csoszi, Tibor, Cubillo, Antonio, DeMarco, Linda, de Wit, Maike, Dragovich, Tomislav, Edenfield, William, Fein, Luis Enrique, Franke, Fábio, Fuchs, Martin, Gonzales-Cruz, Vega, Gozza, Alberto, Fernando, Rivera Herrero, Iaffaioli, Rosario, Jakesova, Jitka, Kahan, Zsuzsanna, Karimi, Misagh, Kim, Jun Suk, Korbenfeld, Ernesto, Lang, Istvan, Lee, Fa-Chyi, Lee, Kuan-Der, Lipton, Lara, Ma, Wen Wee, Mangel, Laszlo, Mena, Raul, Palmer, Daniel, Pant, Shubham, Park, Joon Oh, Piacentini, Paolo, Pelzer, Uwe, Plazas, Javier Gallego, Prasad, Cooray, Rau, Kun-Ming, Raoul, Jean-Luc, Richards, Donald, Ross, Paul, Schlittler, Luis, Smakal, Martin, Stahalova, Vladimira, Sternberg, Cora, Seufferlein, Thomas, Tebbutt, Niall, Vinholes, Jeferson Jose, Wadlow, Raymond, Wenczl, Milkos, Wong, Mark, Wang-Gillam, Andrea, Li, Chung-Pin, Bodoky, György, Dean, Andrew, Shan, Yan-Shen, Jameson, Gayle, Macarulla, Teresa, Lee, Kyung-Hun, Cunningham, David, Blanc, Jean F, Hubner, Richard A, Chiu, Chang-Fang, Schwartsmann, Gilberto, Siveke, Jens T, Braiteh, Fadi, Moyo, Victor, Belanger, Bruce, Dhindsa, Navreet, Bayever, Eliel, Von Hoff, Daniel D, and Chen, Li-Tzong

Published
2016
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96. Quality of life outcomes including neuropathy-associated scale from a phase II, multicenter, randomized trial of eribulin plus gemcitabine versus paclitaxel plus gemcitabine as first-line chemotherapy for HER2-negative metastatic breast cancer: Korean Cancer Study Group Trial (KCSG BR13-11)

Author

Kim, Ji-Yeon, Park, Seri, Im, Seock-Ah, Kim, Sung-Bae, Sohn, Joohyuk, Lee, Keun Seok, Chae, Yee Soo, Lee, Ki Hyeong, Kim, Jee Hyun, Im, Young-Hyuck, Kim, Tae-Yong, Lee, Kyung-Hun, Ahn, Jin-Hee, Kim, Gun Min, Park, In Hae, Lee, Soo Jung, Han, Hye Sook, Kim, Se Hyun, Jung, Kyung Hae, Park, Yeon Hee, and Korean Cancer Study Group

Published
2019
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97. A Survey of Practice Patterns for Clinical Nodal Staging Prior to Neoadjuvant Chemotherapy in Breast Cancer.

Author

Lee, Han-Byoel, Lee, Kyung-Hun, Song, Seok Hyun, Kim, Kyubo, Kim, Hong Kyu, Moon, Hyeong-Gon, Han, Wonshik, Lee, Dae-Won, Im, Seock-Ah, Jang, Bum-Sup, Kim, Yong Bae, Yu, Jonghan, Kim, Jee Hyun, Park, Yeon Hee, Shin, Kyung Hwan, and Chang, Ji Hyun

Subjects
ADJUVANT chemotherapy, MAGNETIC resonance imaging, TUMOR classification, HEALTH insurance reimbursement, CASE studies, DESCRIPTIVE statistics, COMBINED modality therapy, PHYSICIAN practice patterns, DECISION making in clinical medicine, COMPUTED tomography, BREAST tumors
Abstract

Background: The importance of clinical staging in breast cancer has increased owing to the wide use of neoadjuvant systemic therapy (NST). This study aimed to investigate the current practice patterns regarding clinical nodal staging in breast cancer in real-world settings. Materials and Methods: A web-based survey was administered to board-certified oncologists in Korea, including breast surgical, medical, and radiation oncologists, from January to April 2022. The survey included 19 general questions and 4 case-based questions. Results: In total, 122 oncologists (45 radiation, 44 surgical, and 33 medical oncologists) completed the survey. Among them, 108 (88%) responded that clinical staging before NST was primarily performed by breast surgeons. All the respondents referred to imaging studies during nodal staging. Overall, 64 (52.5%) responders determined the stage strictly based on the radiology reports, whereas 58 (47.5%) made their own decision while noting radiology reports. Of those who made their own decisions, 88% referred to the number or size of the suspicious node. Of the 75 respondents involved in prescribing regimens for neoadjuvant chemotherapy, 58 (77.3%) responded that the reimbursement regulations in the selection of NST regimens affected nodal staging in clinical practice. In the case-based questions, high variability was observed among the clinicians in the same cases. Conclusions: Diverse assessments by specialists owing to the lack of a clear, harmonized staging system for the clinical nodal staging of breast cancer can lead to diverse practice patterns. Thus, practical, harmonized, and objective methods for clinical nodal staging and for the outcomes of post-NST response are warranted for appropriate treatment decisions and accurate outcome evaluation. Nodal stage serves a pivotal role in making treatment decisions in breast cancer patients. This study investigated current practice patterns regarding clinical nodal staging in breast cancer in a real-world setting. [ABSTRACT FROM AUTHOR]

Published
2023
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98. Data from Determinants of Response to Talazoparib in Patients with HER2-Negative, Germline BRCA1/2-Mutated Breast Cancer

Author

Blum, Joanne L., primary, Laird, A. Douglas, primary, Litton, Jennifer K., primary, Rugo, Hope S., primary, Ettl, Johannes, primary, Hurvitz, Sara A., primary, Martin, Miguel, primary, Roché, Henri H., primary, Lee, Kyung-Hun, primary, Goodwin, Annabel, primary, Chen, Ying, primary, Lanzalone, Silvana, primary, Chelliserry, Jijumon, primary, Czibere, Akos, primary, Hopkins, Julia F., primary, Albacker, Lee A., primary, and Mina, Lida A., primary

Published
2023
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99. Supplementary Data from Determinants of Response to Talazoparib in Patients with HER2-Negative, Germline BRCA1/2-Mutated Breast Cancer

Author

Blum, Joanne L., primary, Laird, A. Douglas, primary, Litton, Jennifer K., primary, Rugo, Hope S., primary, Ettl, Johannes, primary, Hurvitz, Sara A., primary, Martin, Miguel, primary, Roché, Henri H., primary, Lee, Kyung-Hun, primary, Goodwin, Annabel, primary, Chen, Ying, primary, Lanzalone, Silvana, primary, Chelliserry, Jijumon, primary, Czibere, Akos, primary, Hopkins, Julia F., primary, Albacker, Lee A., primary, and Mina, Lida A., primary

Published
2023
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100. Supplementary Figure from Determinants of Response to Talazoparib in Patients with HER2-Negative, Germline BRCA1/2-Mutated Breast Cancer

Author

Blum, Joanne L., primary, Laird, A. Douglas, primary, Litton, Jennifer K., primary, Rugo, Hope S., primary, Ettl, Johannes, primary, Hurvitz, Sara A., primary, Martin, Miguel, primary, Roché, Henri H., primary, Lee, Kyung-Hun, primary, Goodwin, Annabel, primary, Chen, Ying, primary, Lanzalone, Silvana, primary, Chelliserry, Jijumon, primary, Czibere, Akos, primary, Hopkins, Julia F., primary, Albacker, Lee A., primary, and Mina, Lida A., primary

Published
2023
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