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Supplemental material, sj-pdf-1-ajs-10.1177_03635465211030295 for Use of Platelet-Rich Plasma Plus Suramin, an Antifibrotic Agent, to Improve Muscle Healing After Injuries by Wen-Chung Tsai, Tung-Yang Yu, Gwo-Jyh Chang, Hsiang-Ning Chang, Li-Ping Lin, Miao-Sui Lin and Jong-Hwei S. Pang in The American Journal of Sports Medicine

Polyketide–polyketide hybrids are unique natural products with promising bioactivity, but the hybridization processes remain poorly understood., Polyketide–polyketide hybrids are unique natural products with promising bioactivity, but the hybridization processes remain poorly understood. Herein, we present that the biosynthetic pathways of two immunosuppressants, dalmanol A and acetodalmanol A, result from an unspecific monooxygenase triggered hybridization of two distinct polyketide (naphthalene and chromane) biosynthetic gene clusters. The orchestration of the functional dimorphism of the polyketide synthase (ChrA) ketoreductase (KR) domain (shortened as ChrA KR) with that of the KR partner (ChrB) in the bioassembly line increases the polyketide diversity and allows the fungal generation of plant chromanes (e.g., noreugenin) and phloroglucinols (e.g., 2,4,6-trihydroxyacetophenone). The simultaneous fungal biosynthesis of 1,3,6,8- and 2-acetyl-1,3,6,8-tetrahydroxynaphthalenes was addressed as well. Collectively, the work may symbolize a movement in understanding the multiple-gene-cluster involved natural product biosynthesis, and highlights the possible fungal generations of some chromane- and phloroglucinol-based phytochemicals.

Background: Tea is derived from the leaf of Camellia sinensis, a natural beverage widely consumed around the world. Geological and botanical evidence suggests that the tea plant originated from China. Varying methods of processing tea leaves lead to green tea, black tea, or Oolong tea, which differ in their concentrations of polyphenols. Green tea polyphenols appear to have anti-tumorigenic properties, and form 30-40% of the dry weight of green tea compared with only 3-10% of black tea. Numerous studies in multiple animal models and different cancer cell lines have demonstrated the anti-tumorigenesis by green tea polyphenols. Despite the consistency of laboratory results, evidence of this effect occuring in humans has been inconclusive to date.Objective: To investigate if green tea consumption was associated with longer survival rates in ovarian cancer patients, and a lower risk of ovarian, breast, and colorectal cancer, in addition toadult leukemiaMethods: We have conducted one prospective cohort study in ovarian cancer patients, and fivecase-control studies in ovarian, breast, and colorectal cancers, and leukemia over the past decade. Tea consumption was measured using a structured questionnaire by face-to-face interviews. The validity and reliability of the questionnaire was assessed in a preliminary study, and then evaluated by a test–retest. Cox proportional hazards regression models were used to obtain hazard ratios(HRs), 95% confidence intervals(95% CIs), and were adjusted for age at diagnosis, locality, body mass index(BMI), parity, International Federation of Gynecology and Obstetrics(IFGO) stage, histologic grade of differentiation, cytology of ascites, residual tumour, and chemotherapeutic status. Odds ratios(ORs) and 95% CIs were obtained using logistic regression analyses, which accounted for demographic, lifestyle, hormonal and family cancer factors, and potential confounders.Functional Foods in Health and Disease 2012, 2(10):339-350 Results: Higher green tea consumption was consistently observed as being associated with a lower risk of mortality due to ovarian cancer, and a decreased risk of ovarian, breast, and colorectal cancers, and adult leukemia occurrences in our observational studies. The adjusted HRand 95% CI for case mortality from ovarian cancer was 0.40(0.18-0.90) in the patients who consumed green tea at the highest level compared with non-tea drinkers. Compared with never or seldom tea drinkers, the adjusted ORs ranged from 0.07 to 0.61 for ovarian, breast, and colorectal cancers, and adult leukemia in those who consumed green tea at the highest level. Significant inverse dose-response relationships were also observed for quantity, duration, and frequency of green tea consumed.Conclusion: We concluded that regular consumption of green tea enhanced survival of ovarian cancer, and decreased risks of ovarian, breast, and colorectal cancers, and adult leukemia. Evidence from our observational studies supported the protective effect of green tea against cancers, and this evidence will provide a knowledge platform from which to launch interventional studies for cancer prevention in the next stage.

With China's rapid economic development, people's living standard has been improved quickly, China's luxury market is showing great vitality. In the luxury market, China's domestic brands have only a very small market share. This papers answered what a luxury is., the basic characteristics of luxury goods, the local luxury goods' status and developments. Analysis China's luxury market, find its major problems, propose some strategies. And prospect the tendency of the development of the luxury market.

Modern society, is the information explosion society. More and more people intensely long for knowledge, lifelong learning is no longer unfamiliar. It seems that supply and demand is a very balanced relations. In other words, knowledge has a large demand, and also have a large crowd provide education resource institutions. We can describe this phenomenon very well, image the crowd which seek knowledge as buyers and the provision enterprises as seller, so a new kind of Internet education model can be established, is the education network marketing platform. Education resources become open and it is more convenient for learners to get relevant knowledge.