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52. Software defined environments: An introduction

Author

Li, C.-S., primary, Brech, B. L., additional, Crowder, S., additional, Dias, D. M., additional, Franke, H., additional, Hogstrom, M., additional, Lindquist, D., additional, Pacifici, G., additional, Pappe, S., additional, Rajaraman, B., additional, Rao, J., additional, Ratnaparkhi, R. P., additional, Smith, R. A., additional, and Williams, M. D., additional

Published
2014
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53. Disease Extent ≥4 cm Is a Prognostic Marker of Local Recurrence in T1-2 Breast Cancer

Author

Lindquist, D, Hellberg, Dan, Tot, T, Lindquist, D, Hellberg, Dan, and Tot, T

Abstract

Despite improvements of the therapy for breast cancer, a proportion of the patients still get local recurrence. The status of the surgical margins is the most often used parameter for decision regarding additional treatment. However, a negative margin is not a guarantee that there is not residual cancer left in the breast; additional parameters are needed to better predict the risk of local recurrence. The disease extent was evaluated in the surgical specimen from 313 women after breast-conserving therapy using large-section histology and was correlated to the incidence of local recurrence. A disease extent ≥4 cm was shown to be an independent marker for local recurrence; the cumulative 10-year local relapse rate for the group with a disease extent ≥4 cm was 20.5%, and for the rest 6.7%. We conclude that disease extent ≥4 cm seems to be an important factor when evaluating the risk for local recurrence.

Published
2011
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56. WebExpress: A client/intercept based system for optimizing Web browsing in a wireless environment

Author

Housel, B. C., Samaras, George S., and Lindquist, D. B.

Subjects
World Wide Web, Optimization, Mathematical models, Mobile computing, Wide area networks, HTTP, Network protocols, Wireless wide area networks
Abstract

This paper describes an application model and software technology that makes it possible to run World Wide Web applications in wide area wireless networks. Web technology in conjunction with today's mobile devices (e.g., laptops, notebooks, personal digital assistants) and the emerging wireless technologies (e.g., digital cellular, packet radio, CDPD) offer the potential for unprecedented access to data and applications by mobile workers. Yet, the limited bandwidth, high latency, high cost, and poor reliability of today's wireless wide-area networks greatly inhibits (to the point of infeasibility) supporting such applications over wireless networks. This paper presents the Client/Intercept computational model that makes it possible to run such distributed applications efficiently in wide area wireless networks. Furthermore, it presents WebExpress, a client/intercept based system for optimizing Web browsing, that reduces data volume and latency of wireless communications by intercepting the HTTP data stream and performing various optimizations including: file caching, forms differencing, protocol reduction, and the elimination of redundant HTTP header transmission. This paper describes these optimizations and presents some experimental results. 3 4 419 431 Cited By :34

Published
1998

60. Phase I trial of veliparib, (ABT-888), a poly(ADP-ribose) polymerase (PARP) inhibitor, in combination with doxorubicin and cyclophosphamide in breast cancer and other solid tumors.

Author

Tan, A. R., primary, Toppmeyer, D., additional, Stein, M. N., additional, Moss, R. A., additional, Gounder, M., additional, Lindquist, D. C., additional, Ji, J. J., additional, Chen, A. P., additional, Egorin, M. J., additional, Kiesel, B., additional, Beumer, J. H., additional, and DiPaola, R. S., additional

Published
2011
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61. Randomized, phase III study of adjuvant doxorubicin plus cyclophosphamide (AC) → docetaxel (T) with or without capecitabine (X) in high-risk early breast cancer: Exploratory Ki-67 analyses.

Author

Pippen, J. E., primary, Paul, D., additional, Stokoe, C. T., additional, Blum, J. L., additional, Krekow, L., additional, Holmes, F. A., additional, Lindquist, D. L., additional, Sedlacek, S. M., additional, Rivera, R. R., additional, Brooks, R. J., additional, Vukelja, S. J., additional, McIntyre, K., additional, Lopez-Diaz, C., additional, and O'Shaughnessy, J., additional

Published
2011
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62. Abstract S4-2: First Efficacy Results of a Randomized, Open-Label, Phase III Study of Adjuvant Doxorubicin Plus Cyclophosphamide, Followed by Docetaxel with or without Capecitabine, in High-Risk Early Breast Cancer

Author

O'Shaughnessy, J, primary, Paul, D, additional, Stokoe, C, additional, Pippen Jr, J, additional, Blum, JL, additional, Krekow, L, additional, Holmes, FA, additional, Vukelja, S, additional, Lindquist, D, additional, Sedlacek, S, additional, Rivera, R, additional, Brooks, R, additional, McIntyre, K, additional, Pluenneke, R, additional, Schwartz, J, additional, Jones, S, additional, Brownstein, C, additional, and Gilberg, F., additional

Published
2010
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69. Identification and characterization of Serpulina pilosicoli isolates recovered from the blood of critically ill patients

Author

Trott, D.J., Jensen, N.S., Saint Girons, I., Oxberry, S.L., Stanton, T.B., Lindquist, D., Hampson, D.J., Trott, D.J., Jensen, N.S., Saint Girons, I., Oxberry, S.L., Stanton, T.B., Lindquist, D., and Hampson, D.J.

Abstract

The phenotypic and genetic characteristics of spirochetes isolated from the blood of one U.S. and six French patients with severe clinical disease or impaired immunity were examined. All spirochetes were anaerobic, weakly beta-hemolytic, positive for hippurate hydrolysis, and negative for beta-glucosidase activity. Cell lengths ranged from 4 to 8 microm, and each isolate had between 8 and 12 periplasmic flagella per cell. These features were consistent with the spirochetes' being Serpulina pilosicoli, the agent of intestinal spirochetosis. All isolates were positive in a PCR assay amplifying a portion of the S. pilosicoli 16S rRNA gene, and they all grouped with fecal isolates of S. pilosicoli in multilocus enzyme electrophoresis (MLEE). The blood isolates could be differentiated from each other by MLEE, although the U.S. and two French isolates were closely related. Apparently S. pilosicoli may translocate from the large intestine to establish spirochetemia. The clinical significance of this finding remains uncertain and requires further investigation.

Published
1997

72. Human papillomavirus, p16INK4A, and Ki-67 in relation to clinicopathological variables and survival in primary carcinoma of the vagina.

Author

Hellman, K, Lindquist, D, Ranhem, C, Wilander, E, and Andersson, S

Subjects
VAGINAL cancer, PAPILLOMAVIRUSES, P16 gene, CANCER genetics, PRIMARY care, GENE expression, IMMUNOHISTOCHEMISTRY
Abstract

Background:This study aimed to determine human papillomavirus (HPV) status and to investigate p16INK4A and Ki-67 expression and their correlation with clinical parameters and survival in women with primary carcinoma of the vagina (PCV).Methods:The presence of HPV DNA was evaluated by PCR. Genotyping was performed by Luminex in 68 short-term (2 years) and long-term (8 years) PCV survivors. p16INK4A and Ki-67 expression was evaluated by immunohistochemistry.Results:Human papillomavirus DNA was detected in 43% of patients, the majority (63%) of whom were HPV16 positive. High p16INK4A expression was significantly correlated with low histopathological grade (P=0.004), HPV positivity (P=0.032), and long-term survival (P=0.045). High Ki-67 expression was negatively correlated with histopathological grade (P<0.001) and tumour size (P=0.047). There was an association between HPV positivity and low histopathological grade, but not between HPV positivity and survival.Conclusion:High p16INK4A expression was associated with long-term survival, but the only independent predictors for survival were tumour size and histopathological grade. Our results indicate that p16INK4A and Ki-67 expression might be useful in tumour grading, and that it might be possible to use p16INK4A expression as a marker for HPV positivity, but this has to be further elucidated. [ABSTRACT FROM AUTHOR]

Published
2014
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74. Multicenter evaluation of the MicroScan Rapid Gram-Negative Identification Type 3 Panel

Author

Bascomb, S, primary, Abbott, S L, additional, Bobolis, J D, additional, Bruckner, D A, additional, Connell, S J, additional, Cullen, S K, additional, Daugherty, M, additional, Glenn, D, additional, Janda, J M, additional, Lentsch, S J, additional, Lindquist, D, additional, Mayhew, P B, additional, Nothaft, D M, additional, Skinner, J R, additional, Williams, G B, additional, Wong, J, additional, and Zimmer, B L, additional

Published
1997
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89. Outbreak of Pontiac fever due to Legionella anisa

Author

Fenstersheib, M.D., primary, Miller, M., additional, Diggins, C., additional, Liska, S., additional, Detwiler, L., additional, Werner, S.B., additional, Lindquist, D., additional, Thacker, W.L., additional, and Benson, R.F., additional

Published
1990
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91. Porous Alumina Prepared from Diethylaluminum Amide, Acetone, and Water

Author

Wilcox, L., Burnside, G., Kiranga, B., Shekhawat, R., Mazumder, M. K., Hawk, R. M., Lindquist, D. A., and Burton, S. D.

Abstract

A previously described synthetic method was modified to improve the porosity of the alumina product. The compound (Et2AlNH2)3 was prepared from ammonia and triethylaluminum (Et3Al) in toluene solvent. Addition of acetone to form a solution of ethylaluminoxane (EtAlO) and acetonine (2,2,4,4,6-pentamethyl-2,3,4,5-tetrahydropyrimidine) was followed by addition of two equivalents of water to give an alumina precursor. Alumina precursors also were prepared by the direct hydrolysis of (Et2AlNH2)3. Powder X-ray diffraction, 27Al MAS NMR, and N2 adsorption/desorption isotherms were used to analyze the aluminas after calcination of the precipitates. The aluminas exhibited high pore volume and surface area, and they were amorphous after calcination at 500 °C. One alumina showed a significant fraction of pentacoordinate aluminum after heating to 300 °C in air or 500 °C in steam atmosphere. The products crystallized as α-Al2O3 at the low temperature of 1000 °C, which reduces their applicability for catalysts. Synthesis variables and their effects on alumina properties are discussed.

Published
2003

92. New serogroup of Legionella pneumophila, serogroup 8

Author

Bissett, M L, Lee, J O, and Lindquist, D S

Abstract

A strain of Legionella pneumophila (designated Concord 3) was isolated from a postmortem lung specimen of a patient with pneumonia. Direct fluorescent-antibody and immunoelectrophoresis tests, using absorbed and unabsorbed reagents prepared to this and other strains of legionellae, indicated that the Concord 3 strain represents a new serogroup of L. pneumophila, serogroup 8.

Published
1983
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97. Reports of Special Committees for 1977

Author

Schuder, D. L., primary, Allen, W. W., additional, Arant, F. S., additional, Burke, H. R., additional, Rutschky, C. W., additional, Hill, R. E., additional, Ashlock, P. D., additional, Hodges, R. W., additional, Roberts, R. D., additional, Wellso, S. G., additional, Frank, J. H., additional, Chiang, H. C., additional, Graves, J. B., additional, Haines, R. G., additional, Hoffman, R. A., additional, Kaloostian, G. H., additional, Knapp, F. W., additional, Nettles, W. C., additional, Shockley, C. W., additional, Silbergleid, R. E., additional, Tamashiro, M., additional, Steinhauer, K. L., additional, Knight, K. L., additional, Ezell, W. B., additional, Fisher, R. L., additional, Huddleston, E. W., additional, Kistner, D. H., additional, Minnick, D. R., additional, Nappi, A. J., additional, Shady, J. H., additional, Skeleton, T. E., additional, Turner, W. J., additional, Van Cleave, H. W., additional, Fredrickson, C. J., additional, Lindquist, D. A., additional, Hoogstrall, H., additional, Maxwell, F. G., additional, Pathak, M. D., additional, Witcome, W. H., additional, Tazanakakis, M. E., additional, Koehler, C. S., additional, Williams, R. N., additional, Shoaf, J. V., additional, Bath, J. E., additional, Dewey, J. E., additional, Miner, F. D., additional, Moore, L., additional, Thomas, J. G., additional, Ashdown, D., additional, Craig, G. B., additional, Klostermayer, E. C., additional, Hays, K. L., additional, Smith, E. H., additional, Eden, W. G., additional, Hutton, G. L., additional, Sauer, R. J., additional, Witt, J. W., additional, Opler, R. A., additional, Menzer, R. E., additional, Smith, J. W., additional, Harwood, R. F., additional, cowden, R. L., additional, Harris, M. K., additional, and Mitchell, W. C., additional

Published
1978
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98. Reports of Special Committees for 1978

Author

Adkisson, P. L., primary, Duckworth, D. W., additional, Glass, E. H., additional, Grey, H. E., additional, Klassen, W., additional, Knight, K., additional, Kring, J. R., additional, McLean, D. L., additional, Sailor, R. I., additional, Thomas, J. G., additional, Metcalf, R. L., additional, Beck, S. D., additional, Peters, D. C., additional, Robertson, R. L., additional, Washino, R. D., additional, Duckworth, W. D., additional, Greyson, J. M., additional, Ashlock, P. D., additional, Hodges, R. W., additional, Roberts, R. B., additional, Wellso, S. G., additional, Frank, J. H., additional, Eden, W. G., additional, Hutton, G. L., additional, Sauer, R. J., additional, Witt, J. W., additional, Dewey, J. E., additional, Fredrickson, C. J., additional, Hoogstrall, H., additional, Lindquist, D. A., additional, Maxwell, F. G., additional, Pathak, M. D., additional, Smith, R. F., additional, Tzanakakis, M. E., additional, Whitcome, W. H., additional, William, R. N., additional, Koehler, C. S., additional, Bay, D. E., additional, Ezell, W. B., additional, Fischer, R. L., additional, Huddleston, E. W., additional, Kistner, D. H., additional, Minnick, D. R., additional, Nappi, A. J., additional, Pieters, E. P., additional, Shaddy, J. H., additional, Turner, W. J., additional, Skeleton, T. E., additional, Allen, W. W., additional, Arant, F. S., additional, Hill, R. E., additional, Rutschky, C. W., additional, Burke, H. R., additional, Craig, G. B., additional, Hammen, R. E., additional, Neal, J. W., additional, Tipton, V. J., additional, Weekman, G. T., additional, Smith, E. H., additional, Wood, T. K., additional, Vinson, S. B., additional, Nault, L. R., additional, Loomis, E. C., additional, Miller, R. L., additional, and Danielson, E. M., additional

Published
1979
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99. Reports of Special Committees for 1975

Author

Schuder, D. L., primary, Anderson, J. R., additional, Drake, D. C., additional, Feir, D., additional, Foote, R. H., additional, McIntyre, T., additional, Richerson, J. V., additional, Shenefelt, R. D., additional, Libby, J. L., additional, York, A. C., additional, Sorenson, K. A., additional, Fredrickson, C. J., additional, Lindquist, D. A., additional, Hoogstrall, H., additional, Pathak, M. D., additional, Whitcomb, W. H., additional, Tzanakakis, M. E., additional, Smith, R. F., additional, Williams, R. N., additional, Anderson, J. F., additional, Dewey, J. E., additional, Gunther, F. A., additional, Hamman, P. J., additional, Hutton, G. L., additional, Newsom, L. D., additional, Pitts, C. W., additional, Thomas, J. G., additional, Glass, E. H., additional, Ambrose, J. T., additional, Knight, K. L., additional, Burke, H. R., additional, Ferguson, G. R., additional, Hill, R. E., additional, Tippins, S. H., additional, Berg, C. O., additional, Eden, W. G., additional, McLean, M. D., additional, Smith, E. H., additional, Peters, D. C., additional, Grayson, J. M., additional, Koehler, C. S., additional, Miner, F. D., additional, Randolph, N. M., additional, Ortman, E. E., additional, Rainwater, H. I., additional, Georghiou, G. P., additional, Shaddy, J. H., additional, Skeleton, T. E., additional, Von Cleave, H. W., additional, Tipton, V. J., additional, Silbergleid, R. E., additional, Nettles, W. C., additional, Tamashiro, M., additional, Knapp, F. W., additional, Shockley, C. W., additional, Musick, G. J., additional, Hodson, A. C., additional, O'Brein, C. W., additional, Peterson, D. N., additional, Wellso, S. G., additional, Woodruff, R. E., additional, Young, F. N., additional, Frank, J. H., additional, Canerday, T. D., additional, Hodgson, E., additional, McEvan, F. L., additional, Reynolds, H. T., additional, Dietrick, E. J., additional, Newton, W. H., additional, Osmun, J. V., additional, and Haines, R. G., additional

Published
1976
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100. Reports of Special Committees for 1976

Author

Adkissan, P. L., primary, Schuder, D. L., additional, Allen, W. W., additional, Burkey, H. R., additional, Oertel, E., additional, Rutschky, C. W., additional, Hill, R. E., additional, Ashlock, P. D., additional, Hodges, R. W., additional, Roberts, R. B., additional, Wellso, S. G., additional, Frank, J. H., additional, Eden, W. G., additional, Hutton, G. L., additional, Sauer, R. J., additional, Witt, J. W., additional, Dewey, J. E., additional, Davis, R., additional, Ellington, J., additional, Frankie, G. W., additional, Furman, D. W., additional, Halgren, L. A., additional, Kline, D. L., additional, Marshall, J. D., additional, Ode, P. E., additional, Guthrie, F. E., additional, Shenefelt, R. D., additional, Fredrickson, C. J., additional, Lindquist, D. A., additional, Hoogstrall, H., additional, Pathak, M. D., additional, Witcomb, W. H., additional, Tzanakakis, M. E., additional, Koehler, C. S., additional, Williams, R. N., additional, Rentz, D. C., additional, Dorough, H. W., additional, Doane, C. C., additional, Eldridge, B. F., additional, Bergman, P. W., additional, Davis, A. C., additional, and Tynes, J. S., additional

Published
1977
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