51. Degeneration of leiomyoma in patients referred for uterine fibroid embolization: incidence, imaging features and clinical characteristics
- Author
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Mu Sook Lee, Kwang Hun Lee, Myung Su Lee, Do Yun Lee, Dae Chul Jung, Jong Yun Won, Seung Chul Han, Man Deuk Kim, and Sung Il Park
- Subjects
Adult ,medicine.medical_specialty ,Abdominal pain ,medicine.medical_treatment ,degeneration ,Uterine artery embolization ,Pregnancy ,medicine ,Humans ,In patient ,Menorrhagia ,Retrospective Studies ,Leiomyoma ,uterus ,business.industry ,Incidence (epidemiology) ,Incidence ,Obstetrics and Gynecology ,Retrospective cohort study ,General Medicine ,Middle Aged ,medicine.disease ,Magnetic Resonance Imaging ,female genital diseases and pregnancy complications ,Abdominal Pain ,Treatment Outcome ,Uterine fibroid embolization ,Radiological weapon ,Female ,Original Article ,Radiology ,medicine.symptom ,business ,Follow-Up Studies - Abstract
Purpose Imaging features and clinical characteristics of degenerated leiomyoma in patients referred for uterine fibroid embolization (UFE) were analyzed to assess the incidence of degenerated leiomyoma. Materials and Methods Patients referred for UFE between 2008 and 2009 were retrospectively analyzed (n=276). Patients ranged in age from 27 to 51 years (mean 38.0 years). All patients underwent screening MRI with contrast enhancement. Medical histories and clinical symptoms were evaluated. Results Among the 276 patients who underwent MRI, 14 (5.1%) showed degenerated leiomyomas. Symptoms were abdominal pain (n=4, 26.7%), menorrhagia (n=5, 35.7%) and bulk-related symptoms (n=5, 35.7%) and no symptoms (n=5, 35.7%). Of the 14 patients with degenerated leiomyomas, 5 (42.9%) had a history of pregnancy in the past two years. For T1-weighted imaging (T1WI), a high signal intensity (SI) of the leiomyoma was the most common finding (n=9, 64.3%) and a hyperintense rim (n=4, 28.6%) was the second most common. On T2-weighted imaging (T2WI), a low SI of the leiomyoma was found in six patients (42.9%), a high SI in four (28.6%) and a heterogeneous SI in four (28.6%) patients. Conservative management was performed in 11 (78.6%) patients, surgery in 3 (21.4%) and uterine artery embolization in one (7.1%) patient. Conclusion The incidence of degeneration of leiomyoma in patients referred for UFE was 5.1%. Patients presented with variable clinical symptoms with or without a history of pregnancy. MR imaging showed a high SI on T1WI and various SIs on T2WI without contrast enhancement. An understanding of the degeneration of leiomyomata is essential when considering UFE.
- Published
- 2012