720,267 results on '"Murphy A"'
Search Results
52. Chemodynamic evolution of Sun-like stars in nearby moving groups
- Author
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Lehmann, Christian, Murphy, Michael T., Liu, Fan, and Flynn, Chris
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Astrophysics - Solar and Stellar Astrophysics ,Astrophysics - Astrophysics of Galaxies - Abstract
Sun-like stars are well represented in the solar neighbourhood but are currently under-utilised, with many studies of chemical and kinematic evolution focusing on red giants (which can be observed further away) or turn-off stars (which have well measured ages). Recent surveys (e.g. GALAH) provide spectra for large numbers of nearby Sun-like stars, which provides an opportunity to apply our newly developed method for measuring metallicities, temperatures, and surface gravities - the EPIC algorithm - which yields improved ages via isochrone fitting. We test this on moving groups, by applying it to the large GALAH DR3 sample. This defines a sample of 72,288 solar analogue targets for which the stellar parameter measurements are most precise and reliable. These stars are used to estimate, and test the accuracy and precision of, age measurements derived with the SAMD isochrone fitting algorithm. Using these ages, we recover the age-metallicity relationships for nearby (<= 1 kpc) moving groups, traced by solar analogues, and analyse them with respect to the stellar kinematics. In particular, we found that the age-metallicity relationships of all moving groups follows a particular trend of young (age < 6 Gyr) stars having constant metallicity and older (age >= 6 Gyr) stars decreasing in metallicity with increasing age. The Hercules stream carries the highest fraction of metal-rich young stars (~ 0.1 dex) in our sample, which is consistent with a migrating population of stars from the inner Galaxy, and we discuss the possible causes of this migration in the context of our results., Comment: 13 pages, 10 figures, accepted to MNRAS
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- 2024
- Full Text
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53. Gaussian Process with dissolution spline kernel
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Murphy, Fiona, Bachiller, Marina Navas, D'Arcy, Deirdre M., and Benavoli, Alessio
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Statistics - Methodology ,Statistics - Applications - Abstract
In-vitro dissolution testing is a critical component in the quality control of manufactured drug products. The $\mathrm{f}_2$ statistic is the standard for assessing similarity between two dissolution profiles. However, the $\mathrm{f}_2$ statistic has known limitations: it lacks an uncertainty estimate, is a discrete-time metric, and is a biased measure, calculating the differences between profiles at discrete time points. To address these limitations, we propose a Gaussian Process (GP) with a dissolution spline kernel for dissolution profile comparison. The dissolution spline kernel is a new spline kernel using logistic functions as its basis functions, enabling the GP to capture the expected monotonic increase in dissolution curves. This results in better predictions of dissolution curves. This new GP model reduces bias in the $\mathrm{f}_2$ calculation by allowing predictions to be interpolated in time between observed values, and provides uncertainty quantification. We assess the model's performance through simulations and real datasets, demonstrating its improvement over a previous GP-based model introduced for dissolution testing. We also show that the new model can be adapted to include dissolution-specific covariates. Applying the model to real ibuprofen dissolution data under various conditions, we demonstrate its ability to extrapolate curve shapes across different experimental settings., Comment: 27 pages, 10 figures
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- 2024
54. Reinforcement Learning: An Overview
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Murphy, Kevin
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Computer Science - Artificial Intelligence ,Computer Science - Machine Learning - Abstract
This manuscript gives a big-picture, up-to-date overview of the field of (deep) reinforcement learning and sequential decision making, covering value-based RL, policy-gradient methods, model-based methods, and various other topics (including a very brief discussion of RL+LLMs).
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- 2024
55. Observation of Cosmic-Ray Anisotropy in the Southern Hemisphere with Twelve Years of Data Collected by the IceCube Neutrino Observatory
- Author
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Abbasi, R., Ackermann, M., Adams, J., Agarwalla, S. K., Aguado, T., Aguilar, J. A., Ahlers, M., Alameddine, J. M., Amin, N. M., Andeen, K., Argüelles, C., Ashida, Y., Athanasiadou, S., Axani, S. N., Babu, R., Bai, X., V., A. Balagopal, Baricevic, M., Barwick, S. W., Bash, S., Basu, V., Bay, R., Beatty, J. J., Tjus, J. Becker, Beise, J., Bellenghi, C., BenZvi, S., Berley, D., Bernardini, E., Besson, D. Z., Blaufuss, E., Bloom, L., Blot, S., Bontempo, F., Motzkin, J. Y. Book, Meneguolo, C. Boscolo, Böser, S., Botner, O., Böttcher, J., Braun, J., Brinson, B., Brisson-Tsavoussis, Z., Brostean-Kaiser, J., Brusa, L., Burley, R. T., Butterfield, D., Campana, M. A., Caracas, I., Carloni, K., Carpio, J., Chattopadhyay, S., Chau, N., Chen, Z., Chirkin, D., Choi, S., Clark, B. A., Cochling, C., Coleman, A., Coleman, P., Collin, G. H., Connolly, A., Conrad, J. M., Corley, R., Cowen, D. F., De Clercq, C., DeLaunay, J. J., Delgado, D., Deng, S., Desai, A., Desiati, P., de Vries, K. D., de Wasseige, G., DeYoung, T., Diaz, A., Díaz-Vélez, J. C., Dierichs, P., Dittmer, M., Domi, A., Draper, L., Dujmovic, H., Durnford, D., Dutta, K., DuVernois, M. A., Ehrhardt, T., Eidenschink, L., Eimer, A., Eller, P., Ellinger, E., Mentawi, S. El, Elsässer, D., Engel, R., Erpenbeck, H., Esmail, W., Evans, J., Evenson, P. A., Fan, K. L., Fang, K., Farrag, K., Fazely, A. R., Fedynitch, A., Feigl, N., Fiedlschuster, S., Finley, C., Fischer, L., Fox, D., Franckowiak, A., Fukami, S., Fürst, P., Gallagher, J., Ganster, E., Garcia, A., Garcia, M., Garg, G., Genton, E., Gerhardt, L., Ghadimi, A., Girard-Carillo, C., Glaser, C., Glüsenkamp, T., Gonzalez, J. G., Goswami, S., Granados, A., Grant, D., Gray, S. J., Griffin, S., Griswold, S., Groth, K. M., Guevel, D., Günther, C., Gutjahr, P., Gruchot, K., Ha, C., Haack, C., Hallgren, A., Halve, L., Halzen, F., Hamacher, L., Hamdaoui, H., Minh, M. Ha, Handt, M., Hanson, K., Hardin, J., Harnisch, A. A., Hatch, P., Haungs, A., Häußler, J., Hardy, A., Hayes, W., Helbing, K., Hellrung, J., Hermannsgabner, J., Heuermann, L., Heyer, N., Hickford, S., Hidvegi, A., Hill, C., Hill, G. C., Hmaid, R., Hoffman, K. D., Hori, S., Hoshina, K., Hostert, M., Hou, W., Huber, T., Hultqvist, K., Hünnefeld, M., Hussain, R., Hymon, K., Ishihara, A., Iwakiri, W., Jacquart, M., Jain, S., Janik, O., Jansson, M., Jeong, M., Jin, M., Jones, B. J. P., Kamp, N., Kang, D., Kang, W., Kang, X., Kappes, A., Kappesser, D., Kardum, L., Karg, T., Karl, M., Karle, A., Katil, A., Katz, U., Kauer, M., Kelley, J. L., Khanal, M., Zathul, A. Khatee, Kheirandish, A., Kiryluk, J., Klein, S. R., Kobayashi, Y., Kochocki, A., Koirala, R., Kolanoski, H., Kontrimas, T., Köpke, L., Kopper, C., Koskinen, D. J., Koundal, P., Kowalski, M., Kozynets, T., Krieger, N., Krishnamoorthi, J., Kruiswijk, K., Krupczak, E., Kumar, A., Kun, E., Kurahashi, N., Lad, N., Gualda, C. Lagunas, Lamoureux, M., Larson, M. J., Lauber, F., Lazar, J. P., Lee, J. W., DeHolton, K. Leonard, Leszczyńska, A., Liao, J., Lincetto, M., Liu, Y. T., Liubarska, M., Love, C., Lu, L., Lucarelli, F., Luszczak, W., Lyu, Y., Madsen, J., Magnus, E., Mahn, K. B. M., Makino, Y., Manao, E., Mancina, S., Mand, A., Sainte, W. Marie, Mariş, I. C., Marka, S., Marka, Z., Marsee, M., Martinez-Soler, I., Maruyama, R., Mayhew, F., McNally, F., Mead, J. V., Meagher, K., Mechbal, S., Medina, A., Meier, M., Merckx, Y., Merten, L., Mitchell, J., Montaruli, T., Moore, R. W., Morii, Y., Morse, R., Moulai, M., Moy, A., Mukherjee, T., Naab, R., Nakos, M., Naumann, U., Necker, J., Negi, A., Neste, L., Neumann, M., Niederhausen, H., Nisa, M. U., Noda, K., Noell, A., Novikov, A., Pollmann, A. Obertacke, O'Dell, V., Olivas, A., Orsoe, R., Osborn, J., O'Sullivan, E., Palusova, V., Pandya, H., Park, N., Parker, G. K., Parrish, V., Paudel, E. N., Paul, L., Heros, C. Pérez de los, Pernice, T., Peterson, J., Pizzuto, A., Plum, M., Pontén, A., Popovych, Y., Rodriguez, M. Prado, Pries, B., Procter-Murphy, R., Przybylski, G. T., Pyras, L., Raab, C., Rack-Helleis, J., Rad, N., Ravn, M., Rawlins, K., Rechav, Z., Rehman, A., Resconi, E., Reusch, S., Rhode, W., Riedel, B., Rifaie, A., Roberts, E. J., Robertson, S., Rodan, S., Roellinghoff, G., Rongen, M., Rosted, A., Rott, C., Ruhe, T., Ruohan, L., Ryckbosch, D., Safa, I., Saffer, J., Salazar-Gallegos, D., Sampathkumar, P., Sandrock, A., Santander, M., Sarkar, S., Savelberg, J., Savina, P., Schaile, P., Schaufel, M., Schieler, H., Schindler, S., Schlickmann, L., Schlüter, B., Schlüter, F., Schmeisser, N., Schmidt, E., Schmidt, T., Schneider, J., Schröder, F. G., Schumacher, L., Schwirn, S., Sclafani, S., Seckel, D., Seen, L., Seikh, M., Seo, M., Seunarine, S., Myhr, P. Sevle, Shah, R., Shefali, S., Shimizu, N., Silva, M., Simmons, A., Skrzypek, B., Smithers, B., Snihur, R., Soedingrekso, J., Søgaard, A., Soldin, D., Soldin, P., Sommani, G., Spannfellner, C., Spiczak, G. M., Spiering, C., Stachurska, J., Stamatikos, M., Stanev, T., Stezelberger, T., Stürwald, T., Stuttard, T., Sullivan, G. W., Taboada, I., Ter-Antonyan, S., Terliuk, A., Thiesmeyer, M., Thompson, W. G., Thorpe, A., Thwaites, J., Tilav, S., Tollefson, K., Tönnis, C., Toscano, S., Tosi, D., Trettin, A., Turcotte, R., Elorrieta, M. A. Unland, Upadhyay, A. K., Upshaw, K., Vaidyanathan, A., Valtonen-Mattila, N., Vandenbroucke, J., van Eijndhoven, N., Vannerom, D., van Santen, J., Vara, J., Varsi, F., Veitch-Michaelis, J., Venugopal, M., Vereecken, M., Carrasco, S. Vergara, Verpoest, S., Veske, D., Vijai, A., Walck, C., Wang, A., Weaver, C., Weigel, P., Weindl, A., Weldert, J., Wen, A. Y., Wendt, C., Werthebach, J., Weyrauch, M., Whitehorn, N., Wiebusch, C. H., Williams, D. R., Witthaus, L., Wolf, M., Woodward, H., Wrede, G., Xu, X. W., Yanez, J. P., Yildizci, E., Yoshida, S., Young, R., Yu, S., Yuan, T., Zegarelli, A., Zhang, S., Zhang, Z., Zhelnin, P., Zilberman, P., and Zimmerman, M.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
We analyzed the 7.92$\times 10^{11}$ cosmic-ray-induced muon events collected by the IceCube Neutrino Observatory from May 13, 2011, when the fully constructed experiment started to take data, to May 12, 2023. This dataset provides an up-to-date cosmic-ray arrival direction distribution in the Southern Hemisphere with unprecedented statistical accuracy covering more than a full period length of a solar cycle. Improvements in Monte Carlo event simulation and better handling of year-to-year differences in data processing significantly reduce systematic uncertainties below the level of statistical fluctuations compared to the previously published results. We confirm the observation of a change in the angular structure of the cosmic-ray anisotropy between 10 TeV and 1 PeV, more specifically in the 100-300 TeV energy range.
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- 2024
56. First search for atmospheric millicharged particles with the LUX-ZEPLIN experiment
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Aalbers, J., Akerib, D. S., Musalhi, A. K. Al, Alder, F., Amarasinghe, C. S., Ames, A., Anderson, T. J., Angelides, N., Araújo, H. M., Armstrong, J. E., Arthurs, M., Baker, A., Balashov, S., Bang, J., Bargemann, J. W., Barillier, E. E., Bauer, D., Beattie, K., Benson, T., Bhatti, A., Biekert, A., Biesiadzinski, T. P., Birch, H. J., Bishop, E., Blockinger, G. M., Boxer, B., Brew, C. A. J., Brás, P., Burdin, S., Buuck, M., Carmona-Benitez, M. C., Carter, M., Chawla, A., Chen, H., Cherwinka, J. J., Chin, Y. T., Chott, N. I., Converse, M. V., Coronel, R., Cottle, A., Cox, G., Curran, D., Dahl, C. E., Darlington, I., Dave, S., David, A., Delgaudio, J., Dey, S., de Viveiros, L., Di Felice, L., Ding, C., Dobson, J. E. Y., Druszkiewicz, E., Dubey, S., Eriksen, S. R., Fan, A., Fayer, S., Fearon, N. M., Fieldhouse, N., Fiorucci, S., Flaecher, H., Fraser, E. D., Fruth, T. M. A., Gaitskell, R. J., Geffre, A., Genovesi, J., Ghag, C., Ghosh, A., Gibbons, R., Gokhale, S., Green, J., van der Grinten, M. G. D., Haiston, J. J., Hall, C. R., Hall, T. J., Han, S., Hartigan-O'Connor, E., Haselschwardt, S. J., Hernandez, M. A., Hertel, S. A., Heuermann, G., Homenides, G. J., Horn, M., Huang, D. Q., Hunt, D., Jacquet, E., James, R. S., Johnson, J., Kaboth, A. C., Kamaha, A. C., K., Meghna K., Khaitan, D., Khazov, A., Khurana, I., Kim, J., Kim, Y. D., Kingston, J., Kirk, R., Kodroff, D., Korley, L., Korolkova, E. V., Kraus, H., Kravitz, S., Kreczko, L., Kudryavtsev, V. A., Lawes, C., Leonard, D. S., Lesko, K. T., Levy, C., Lin, J., Lindote, A., Lippincott, W. H., Lopes, M. I., Lorenzon, W., Lu, C., Luitz, S., Majewski, P. A., Manalaysay, A., Mannino, R. L., Maupin, C., McCarthy, M. E., McDowell, G., McKinsey, D. N., McLaughlin, J., McLaughlin, J. B., McMonigle, R., Mizrachi, E., Monte, A., Monzani, M. E., Mendoza, J. D. Morales, Morrison, E., Mount, B. J., Murdy, M., Murphy, A. St. J., Naylor, A., Nelson, H. N., Neves, F., Nguyen, A., O'Brien, C. L., Olcina, I., Oliver-Mallory, K. C., Orpwood, J., Oyulmaz, K. Y, Palladino, K. J., Palmer, J., Pannifer, N. J., Parveen, N., Patton, S. J., Penning, B., Pereira, G., Perry, E., Pershing, T., Piepke, A., Qie, Y., Reichenbacher, J., Rhyne, C. A., Richards, A., Riffard, Q., Rischbieter, G. R. C., Ritchey, E., Riyat, H. S., Rosero, R., Rushton, T., Rynders, D., Santone, D., Sazzad, A. B. M. R., Schnee, R. W., Sehr, G., Shafer, B., Shaw, S., Shutt, T., Silk, J. J., Silva, C., Sinev, G., Siniscalco, J., Smith, R., Solovov, V. N., Sorensen, P., Soria, J., Stancu, I., Stevens, A., Stifter, K., Suerfu, B., Sumner, T. J., Szydagis, M., Tiedt, D. R., Timalsina, M., Tong, Z., Tovey, D. R., Tranter, J., Trask, M., Tripathi, M., Usón, A., Vacheret, A., Vaitkus, A. C., Valentino, O., Velan, V., Wang, A., Wang, J. J., Wang, Y., Watson, J. R., Weeldreyer, L., Whitis, T. J., Wild, K., Williams, M., Wisniewski, W. J., Wolf, L., Wolfs, F. L. H., Woodford, S., Woodward, D., Wright, C. J., Xia, Q., Xu, J., Xu, Y., Yeh, M., Yeum, D., Zha, W., and Zweig, E. A.
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High Energy Physics - Experiment - Abstract
We report on a search for millicharged particles (mCPs) produced in cosmic ray proton atmospheric interactions using data collected during the first science run of the LUX-ZEPLIN experiment. The mCPs produced by two processes -- meson decay and proton bremsstrahlung -- are considered in this study. This search utilized a novel signature unique to liquid xenon (LXe) time projection chambers (TPCs), allowing sensitivity to mCPs with masses ranging from 10 to 1000 MeV/c$^2$ and fractional charges between 0.001 and 0.02 of the electron charge e. With an exposure of 60 live days and a 5.5 tonne fiducial mass, we observed no significant excess over background. This represents the first experimental search for atmospheric mCPs and the first search for mCPs using an underground LXe experiment.
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- 2024
57. HD 60435: The star that stopped pulsating
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Kurtz, Donald W., Handler, Gerald, Holdsworth, Daniel L., Cunha, Margarida S., Saio, Hideyuki, Medupe, Thebe, Murphy, Simon J., Krüger, Joachim, Brunsden, E., Antoci, Victoria, Hey, Daniel R., Shitrit, Noi, and Matthews, Jaymie M.
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Astrophysics - Solar and Stellar Astrophysics - Abstract
HD 60435 is a well-known rapidly oscillating (roAp) Ap star with a series of alternating even and odd degree modes, making it a prime asteroseismic target. It is also an oblique pulsator with rotational inclination, $i$, and magnetic/pulsation obliquity, $\beta$, such that both magnetic/pulsation poles are viewed over the rotation period, $P_{\rm rot} = 7.679696$ d, determined from rotational light variations. While some roAp stars have stable pulsation mode amplitudes over decades, HD 60435 is known to have amplitude variations on time scales as short as 1 d. We show from 5 yr of {\it TESS} observations that there is strong amplitude modulation on this short time scale with possible mode interactions. Most remarkably, HD 60435 stopped pulsating during the time span of the {\it TESS} observations. This is the first time that any pulsating star has been observed to cease pulsating entirely. That has implications for mode interaction, excitation and damping, and is relevant to the problem of why only some stars in many pulsation instability strips pulsate, while others do not. During a 24.45-d time span of the {\it TESS} data when there was mode stability for a dipole mode and a quadrupole mode, the oblique pulsator model constrained $i$ and $\beta$, which we used to model those modes with a magnetic pulsation model from which we determined a polar field strength of 4 kG, in good agreement with a known magnetic measurement. We modelled the frequency separations showing that they can constrain the global metallicity, something that is not possible from spectroscopy of the highly peculiar Ap atmosphere., Comment: 19 pages plus an appendix. 13 figures. Accepted for publication in MNRAS
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- 2024
58. The radio properties of the JWST-discovered AGN
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Mazzolari, G., Gilli, R., Maiolino, R., Prandoni, I., Delvecchio, I., Norman, C., Jimenez-Andrade, E. F., Belladitta, S., Vito, F., Momjian, E., Chiaberge, M., Trefoloni, B., Signorini, M., Ji, X., D'Amato, Q., Risaliti, G., Baldi, R. D., Fabian, A., Übler, H., D'Eugenio, F., Scholtz, J., Juodžbalis, I., Mignoli, M., Brusa, M., Murphy, E., and Muxlow, T. W. B.
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Astrophysics - Astrophysics of Galaxies ,Astrophysics - Cosmology and Nongalactic Astrophysics - Abstract
We explore the radio emission of spectroscopically confirmed, X-ray weak, Broad Line AGN (BLAGN, or type 1) selected with JWST in the GOODS-N field, one of the fields with the best combination of deep radio observations and statistics of JWST-selected BLAGN. We use deep radio data at different frequencies (144\,MHz, 1.5\,GHz, 3\,GHz, 5.5\,GHz, 10\,GHz), and we find that none of the 22 sources investigated is detected at any of the aforementioned frequencies. Similarly, the radio stacking analysis does not reveal any detection down to an rms of $\sim 0.2\mu$Jy beam$^{-1}$, corresponding to a $3\sigma$ upper limit at rest frame 5 GHz of $L_{5GHz}=2\times10^{39}$ erg s$^{-1}$ at the mean redshift of the sample $z\sim 5.2$. We compared this and individual sources upper limits with expected radio luminosities estimated assuming different AGN scaling relations. For most of the sources the radio luminosity upper limits are still compatible with expectations for radio-quiet (RQ) AGN; nevertheless, the more stringent stacking upper limits and the fact that no detection is found would suggest that JWST-selected BLAGN are weaker than standard AGN even at radio frequencies. We discuss some scenarios that could explain the possible radio weakness, such as free-free absorption from a dense medium, or the lack of either magnetic field or a corona, possibly as a consequence of super-Eddington accretion. These scenarios would also explain the observed X-ray weakness. We also conclude that $\sim$1 dex more sensitive radio observations are needed to better constrain the level of radio emission (or lack thereof) for the bulk of these sources. The Square Kilometer Array Observatory (SKAO) will likely play a crucial role in assessing the properties of this AGN population., Comment: Submitted to A&A, comments are welcome
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- 2024
59. Spectral theory of effective transport for discrete uniaxial polycrystalline materials
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Murphy, N. Benjamin, Hallman, Daniel, Cherkaev, Elena, and Golden, Kenneth M.
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Mathematical Physics ,Condensed Matter - Materials Science ,Mathematics - Functional Analysis ,Mathematics - Numerical Analysis ,Physics - Applied Physics - Abstract
We previously demonstrated that the bulk transport coefficients of uniaxial polycrystalline materials, including electrical and thermal conductivity, diffusivity, complex permittivity, and magnetic permeability, have Stieltjes integral representations involving spectral measures of self-adjoint random operators. The integral representations follow from resolvent representations of physical fields involving these self-adjoint operators, such as the electric field $\boldsymbol{E}$ and current density $\boldsymbol{J}$ associated with conductive media with local conductivity $\boldsymbol{\sigma}$ and resistivity $\boldsymbol{\rho}$ matrices. In this article, we provide a discrete matrix analysis of this mathematical framework which parallels the continuum theory. We show that discretizations of the operators yield real-symmetric random matrices which are composed of projection matrices. We derive discrete resolvent representations for $\boldsymbol{E}$ and $\boldsymbol{J}$ involving the matrices which lead to eigenvector expansions of $\boldsymbol{E}$ and $\boldsymbol{J}$. We derive discrete Stieltjes integral representations for the components of the effective conductivity and resistivity matrices, $\boldsymbol{\sigma}^*$ and $\boldsymbol{\rho}^*$, involving spectral measures for the real-symmetric random matrices, which are given explicitly in terms of their real eigenvalues and orthonormal eigenvectors. We provide a projection method that uses properties of the projection matrices to show that the spectral measure can be computed by much smaller matrices, which leads to a more efficient and stable numerical algorithm for the computation of bulk transport coefficients and physical fields. We demonstrate this algorithm by numerically computing the spectral measure and current density for model 2D and 3D isotropic polycrystalline media with checkerboard microgeometry.
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- 2024
60. Shadow of the (Hierarchical) Tree: Reconciling Symbolic and Predictive Components of the Neural Code for Syntax
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Murphy, Elliot
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Computer Science - Computation and Language - Abstract
Natural language syntax can serve as a major test for how to integrate two infamously distinct frameworks: symbolic representations and connectionist neural networks. Building on a recent neurocomputational architecture for syntax (ROSE), I discuss the prospects of reconciling the neural code for hierarchical 'vertical' syntax with linear and predictive 'horizontal' processes via a hybrid neurosymbolic model. I argue that the former can be accounted for via the higher levels of ROSE in terms of vertical phrase structure representations, while the latter can explain horizontal forms of linguistic information via the tuning of the lower levels to statistical and perceptual inferences. One prediction of this is that artificial language models will contribute to the cognitive neuroscience of horizontal morphosyntax, but much less so to hierarchically compositional structures. I claim that this perspective helps resolve many current tensions in the literature. Options for integrating these two neural codes are discussed, with particular emphasis on how predictive coding mechanisms can serve as interfaces between symbolic oscillatory phase codes and population codes for the statistics of linearized aspects of syntax. Lastly, I provide a neurosymbolic mathematical model for how to inject symbolic representations into a neural regime encoding lexico-semantic statistical features.
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- 2024
61. Spin Qubit Performance at the Error Correction Threshold: Advancing Quantum Information Processing Above 700 mK
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Amitonov, S., Aprà, A., Asker, M., Bals, R., Barry, B., Bashir, I., Blokhina, E., Giounanlis, P., Harkin, M., Hanos-Puskai, P., Kriekouki, I., Leipold, D., Moras, M., Murphy, N., Petropoulos, N., Power, C., Sammak, A., Samkharadze, N., Semenov, A., Sokolov, A., Redmond, D., Rohrbacher, C., and Wu, X.
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Quantum Physics - Abstract
This paper presents a characterization of a two-qubit processor in a 6-quantum dot array in SiGe, from the perspective of its quantum information processing capabilities. The analysis includes randomized benchmarking of single- and two-qubit gates, SPAM characterization, and Bell's state tomography; all basic functionality required for universal quantum computation. In light of our efforts to combine spin qubits with integrated cryogenic electronics, we evaluate the qubits' performance metrics at 300mK and 740mK. The latter temperature lies within the realistic thermal budget for integrated cryogenic electronics, making it particularly relevant for assessing qubit performance in practical scenarios., Comment: 13 pages, 7 figures, 4 tables
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- 2024
62. Bounds on the complex viscoelasticity for surface waves on ice-covered seas
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Sampson, C., Hallman, D., Murphy, N. B., Cherkaev, E., and Golden, K. M.
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Physics - Geophysics - Abstract
Oceanic wave propagation through Earth's sea ice covers is a critical component of accurate ice and climate modeling. Continuum models of the polar ocean surface layer are characterized rheologically by the effective complex viscoelasticity of the composite of ice floes and sea water. Here we present the first rigorous theory of this parameter, and distill its dependence on mixture geometry into the spectral properties of a self-adjoint operator analogous to the Hamiltonian in quantum physics. Bounds for the complex viscoelasticity are obtained from the sea ice concentration and the contrast between the elastic and viscous properties of the ice and water/slush constituents. We find that several published wave attenuation datasets in both laboratory and field settings fall well within the bounds for specific contrast values of the ice/ocean composite., Comment: 10 pages, 1 figure
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- 2024
63. Spectral theory of effective transport for continuous uniaxial polycrystalline materials
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Murphy, N. Benjamin, Hallman, Daniel, Cherkaev, Elena, and Golden, Kenneth M.
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Mathematical Physics ,Condensed Matter - Materials Science ,Mathematics - Analysis of PDEs ,Mathematics - Functional Analysis ,Physics - Applied Physics - Abstract
Following seminal work in the early 1980s that established the existence and representations of the homogenized transport coefficients for two phase random media, we develop a mathematical framework that provides Stieltjes integral representations for the bulk transport coefficients for uniaxial polycrystalline materials, involving spectral measures of self-adjoint random operators, which are compositions of non-random and random projection operators. We demonstrate the same mathematical framework also describes two-component composites, with a simple substitution of the random projection operator, making the mathematical descriptions of these two distinct physical systems directly analogous to one another. A detailed analysis establishes the operators arising in each setting are indeed self-adjoint on an $L^2$-type Hilbert space, providing a rigorous foundation to the formal spectral theoretic framework established by Golden and Papanicolaou in 1983. An abstract extension of the Helmholtz theorem also leads to integral representations for the inverses of effective parameters, e.g., effective conductivity and resistivity. An alternate formulation of the effective parameter problem in terms of a Sobolev-type Hilbert space provides a rigorous foundation for an approach first established by Bergman and Milton. We show that the correspondence between the two formulations is a one-to-one isometry. Rigorous bounds that follow from such Stieltjes integrals and partial knowledge about the material geometry are reviewed and validated by numerical calculations of the effective parameters for polycrystalline media.
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- 2024
64. The track-length extension fitting algorithm for energy measurement of interacting particles in liquid argon TPCs and its performance with ProtoDUNE-SP data
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DUNE Collaboration, Abud, A. Abed, Abi, B., Acciarri, R., Acero, M. A., Adames, M. R., Adamov, G., Adamowski, M., Adams, D., Adinolfi, M., Adriano, C., Aduszkiewicz, A., Aguilar, J., Akbar, F., Alex, N. S., Allison, K., Monsalve, S. Alonso, Alrashed, M., Alton, A., Alvarez, R., Alves, T., Amar, H., Amedo, P., Anderson, J., Andreopoulos, C., Andreotti, M., Andrews, M. P., Andrianala, F., Andringa, S., Anfimov, N., Ankowski, A., Antic, D., Antoniassi, M., Antonova, M., Antoshkin, A., Aranda-Fernandez, A., Arellano, L., Diaz, E. Arrieta, Arroyave, M. A., Asaadi, J., Ashkenazi, A., Asner, D., Asquith, L., Atkin, E., Auguste, D., Aurisano, A., Aushev, V., Autiero, D., Azam, M. B., Azfar, F., Back, A., Back, H., Back, J. J., Bagaturia, I., Bagby, L., Balashov, N., Balasubramanian, S., Baldi, P., Baldini, W., Baldonedo, J., Baller, B., Bambah, B., Banerjee, R., Barao, F., Barbu, D., Barenboim, G., Alzás, P. Barham, Barker, G. J., Barkhouse, W., Barr, G., Monarca, J. Barranco, Barros, A., Barros, N., Barrow, D., Barrow, J. L., Basharina-Freshville, A., Bashyal, A., Basque, V., Batchelor, C., Bathe-Peters, L., Battat, J. B. R., Battisti, F., Bay, F., Bazetto, M. C. Q., Alba, J. L. L. Bazo, Beacom, J. F., Bechetoille, E., Behera, B., Belchior, E., Bell, G., Bellantoni, L., Bellettini, G., Bellini, V., Beltramello, O., Benekos, N., Montiel, C. Benitez, Benjamin, D., Neves, F. Bento, Berger, J., Berkman, S., Bernal, J., Bernardini, P., Bersani, A., Bertolucci, S., Betancourt, M., Rodríguez, A. Betancur, Bevan, A., Bezawada, Y., Bezerra, A. T., Bezerra, T. J., Bhat, A., Bhatnagar, V., Bhatt, J., Bhattacharjee, M., Bhattacharya, M., Bhuller, S., Bhuyan, B., Biagi, S., Bian, J., Biery, K., Bilki, B., Bishai, M., Bitadze, A., Blake, A., Blaszczyk, F. D., Blazey, G. C., Blucher, E., Bodek, A., Bogenschuetz, J., Boissevain, J., Bolognesi, S., Bolton, T., Bomben, L., Bonesini, M., Bonilla-Diaz, C., Bonini, F., Booth, A., Boran, F., Bordoni, S., Merlo, R. Borges, Borkum, A., Bostan, N., Bouet, R., Boza, J., Bracinik, J., Brahma, B., Brailsford, D., Bramati, F., Branca, A., Brandt, A., Bremer, J., Brew, C., Brice, S. J., Brio, V., Brizzolari, C., Bromberg, C., Brooke, J., Bross, A., Brunetti, G., Brunetti, M., Buchanan, N., Budd, H., Buergi, J., Bundock, A., Burgardt, D., Butchart, S., V., G. Caceres, Cagnoli, I., Cai, T., Calabrese, R., Calcutt, J., Calivers, L., Calvo, E., Caminata, A., Camino, A. F., Campanelli, W., Campani, A., Benitez, A. Campos, Canci, N., Capó, J., Caracas, I., Caratelli, D., Carber, D., Carceller, J. M., Carini, G., Carlus, B., Carneiro, M. F., Carniti, P., Terrazas, I. Caro, Carranza, H., Carrara, N., Carroll, L., Carroll, T., Carter, A., Casarejos, E., Casazza, D., Forero, J. F. Castaño, Castaño, F. A., Castillo, A., Castromonte, C., Catano-Mur, E., Cattadori, C., Cavalier, F., Cavanna, F., Centro, S., Cerati, G., Cerna, C., Cervelli, A., Villanueva, A. Cervera, Chakraborty, K., Chalifour, M., Chappell, A., Charitonidis, N., Chatterjee, A., Chen, H., Chen, M., Chen, W. C., Chen, Y., Chen-Wishart, Z., Cherdack, D., Chi, C., Chiapponi, F., Chirco, R., Chitirasreemadam, N., Cho, K., Choate, S., Choi, G., Chokheli, D., Chong, P. S., Chowdhury, B., Christian, D., Chukanov, A., Chung, M., Church, E., Cicala, M. F., Cicerchia, M., Cicero, V., Ciolini, R., Clarke, P., Cline, G., Coan, T. E., Cocco, A. G., Coelho, J. A. B., Cohen, A., Collazo, J., Collot, J., Conley, E., Conrad, J. M., Convery, M., Copello, S., Cova, P., Cox, C., Cremaldi, L., Cremonesi, L., Crespo-Anadón, J. I., Crisler, M., Cristaldo, E., Crnkovic, J., Crone, G., Cross, R., Cudd, A., Cuesta, C., Cui, Y., Curciarello, F., Cussans, D., Dai, J., Dalager, O., Dallavalle, R., Dallaway, W., D'Amico, R., da Motta, H., Dar, Z. A., Darby, R., Peres, L. Da Silva, David, Q., Davies, G. S., Davini, S., Dawson, J., De Aguiar, R., De Almeida, P., Debbins, P., De Bonis, I., Decowski, M. P., de Gouvêa, A., De Holanda, P. C., Astiz, I. L. De Icaza, De Jong, P., Sanchez, P. Del Amo, De la Torre, A., De Lauretis, G., Delbart, A., Delepine, D., Delgado, M., Dell'Acqua, A., Monache, G. Delle, Delmonte, N., De Lurgio, P., Demario, R., De Matteis, G., Neto, J. R. T. de Mello, DeMuth, D. M., Dennis, S., Densham, C., Denton, P., Deptuch, G. W., De Roeck, A., De Romeri, V., Detje, J. P., Devine, J., Dharmapalan, R., Dias, M., Diaz, A., Díaz, J. S., Díaz, F., Di Capua, F., Di Domenico, A., Di Domizio, S., Di Falco, S., Di Giulio, L., Ding, P., Di Noto, L., Diociaiuti, E., Distefano, C., Diurba, R., Diwan, M., Djurcic, Z., Doering, D., Dolan, S., Dolek, F., Dolinski, M. J., Domenici, D., Domine, L., Donati, S., Donon, Y., Doran, S., Douglas, D., Doyle, T. A., Dragone, A., Drielsma, F., Duarte, L., Duchesneau, D., Duffy, K., Dugas, K., Dunne, P., Dutta, B., Duyang, H., Dwyer, D. A., Dyshkant, A. S., Dytman, S., Eads, M., Earle, A., Edayath, S., Edmunds, D., Eisch, J., Englezos, P., Ereditato, A., Erjavec, T., Escobar, C. O., Evans, J. J., Ewart, E., Ezeribe, A. C., Fahey, K., Fajt, L., Falcone, A., Fani', M., Farnese, C., Farrell, S., Farzan, Y., Fedoseev, D., Felix, J., Feng, Y., Fernandez-Martinez, E., Ferry, G., Fialova, E., Fields, L., Filip, P., Filkins, A., Filthaut, F., Fine, R., Fiorillo, G., Fiorini, M., Fogarty, S., Foreman, W., Fowler, J., Franc, J., Francis, K., Franco, D., Franklin, J., Freeman, J., Fried, J., Friedland, A., Fuess, S., Furic, I. K., Furman, K., Furmanski, A. P., Gaba, R., Gabrielli, A., Gago, A. M., Galizzi, F., Gallagher, H., Gallice, N., Galymov, V., Gamberini, E., Gamble, T., Ganacim, F., Gandhi, R., Ganguly, S., Gao, F., Gao, S., Garcia-Gamez, D., García-Peris, M. 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M., Gwon, S., Habig, A., Hadavand, H., Haegel, L., Haenni, R., Hagaman, L., Hahn, A., Haiston, J., Hakenmüller, J., Hamernik, T., Hamilton, P., Hancock, J., Happacher, F., Harris, D. A., Hart, A. L., Hartnell, J., Hartnett, T., Harton, J., Hasegawa, T., Hasnip, C. M., Hatcher, R., Hayrapetyan, K., Hays, J., Hazen, E., He, M., Heavey, A., Heeger, K. M., Heise, J., Hellmuth, P., Henry, S., Herner, K., Hewes, V., Higuera, A., Hilgenberg, C., Hillier, S. J., Himmel, A., Hinkle, E., Hirsch, L. R., Ho, J., Hoff, J., Holin, A., Holvey, T., Hoppe, E., Horiuchi, S., Horton-Smith, G. A., Houdy, T., Howard, B., Howell, R., Hristova, I., Hronek, M. S., Huang, J., Huang, R. G., Hulcher, Z., Ibrahim, M., Iles, G., Ilic, N., Iliescu, A. M., Illingworth, R., Ingratta, G., Ioannisian, A., Irwin, B., Isenhower, L., Oliveira, M. Ismerio, Itay, R., Jackson, C. M., Jain, V., James, E., Jang, W., Jargowsky, B., Jena, D., Jentz, I., Ji, X., Jiang, C., Jiang, J., Jiang, L., Jipa, A., Jo, J. H., Joaquim, F. R., Johnson, W., Jollet, C., Jones, B., Jones, R., Jovancevic, N., Judah, M., Jung, C. K., Jung, K. Y., Junk, T., Jwa, Y., Kabirnezhad, M., Kaboth, A. C., Kadenko, I., Kakorin, I., Kalitkina, A., Kalra, D., Kandemir, M., Kaplan, D. M., Karagiorgi, G., Karaman, G., Karcher, A., Karyotakis, Y., Kasai, S., Kasetti, S. P., Kashur, L., Katsioulas, I., Kauther, A., Kazaryan, N., Ke, L., Kearns, E., Keener, P. T., Kelly, K. J., Kemp, E., Kemularia, O., Kermaidic, Y., Ketchum, W., Kettell, S. H., Khabibullin, M., Khan, N., Khvedelidze, A., Kim, D., Kim, J., Kim, M. J., King, B., Kirby, B., Kirby, M., Kish, A., Klein, J., Kleykamp, J., Klustova, A., Kobilarcik, T., Koch, L., Koehler, K., Koerner, L. W., Koh, D. H., Kolupaeva, L., Korablev, D., Kordosky, M., Kosc, T., Kose, U., Kostelecký, V. A., Kothekar, K., Kotler, I., Kovalcuk, M., Kozhukalov, V., Krah, W., Kralik, R., Kramer, M., Kreczko, L., Krennrich, F., Kreslo, I., Kroupova, T., Kubota, S., Kubu, M., Kudenko, Y., Kudryavtsev, V. 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V., Vannozzi, A., Van Nuland-Troost, M., Varanini, F., Oliva, D. Vargas, Vasina, S., Vaughan, N., Vaziri, K., Vázquez-Ramos, A., Vega, J., Ventura, S., Verdugo, A., Vergani, S., Verzocchi, M., Vetter, K., Vicenzi, M., de Souza, H. Vieira, Vignoli, C., Vilela, C., Villa, E., Viola, S., Viren, B., Vizarreta, R., Hernandez, A. P. Vizcaya, Vuong, Q., Waldron, A. V., Wallbank, M., Walsh, J., Walton, T., Wang, H., Wang, J., Wang, L., Wang, M. H. L. S., Wang, X., Wang, Y., Warburton, K., Warner, D., Warsame, L., Wascko, M. O., Waters, D., Watson, A., Wawrowska, K., Weber, A., Weber, C. M., Weber, M., Wei, H., Weinstein, A., Westerdale, S., Wetstein, M., Whalen, K., White, A., Whitehead, L. H., Whittington, D., Wilhlemi, J., Wilking, M. J., Wilkinson, A., Wilkinson, C., Wilson, F., Wilson, R. J., Winter, P., Wisniewski, W., Wolcott, J., Wolfs, J., Wongjirad, T., Wood, A., Wood, K., Worcester, E., Worcester, M., Wospakrik, M., Wresilo, K., Wret, C., Wu, S., Wu, W., Wurm, M., Wyenberg, J., Xiao, Y., Xiotidis, I., Yaeggy, B., Yahlali, N., Yandel, E., Yang, J., Yang, K., Yang, T., Yankelevich, A., Yershov, N., Yonehara, K., Young, T., Yu, B., Yu, H., Yu, J., Yu, Y., Yuan, W., Zaki, R., Zalesak, J., Zambelli, L., Zamorano, B., Zani, A., Zapata, O., Zazueta, L., Zeller, G. P., Zennamo, J., Zeug, K., Zhang, C., Zhang, S., Zhao, M., Zhivun, E., Zimmerman, E. D., Zucchelli, S., Zuklin, J., Zutshi, V., and Zwaska, R.
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Physics - Instrumentation and Detectors ,High Energy Physics - Experiment - Abstract
This paper introduces a novel track-length extension fitting algorithm for measuring the kinetic energies of inelastically interacting particles in liquid argon time projection chambers (LArTPCs). The algorithm finds the most probable offset in track length for a track-like object by comparing the measured ionization density as a function of position with a theoretical prediction of the energy loss as a function of the energy, including models of electron recombination and detector response. The algorithm can be used to measure the energies of particles that interact before they stop, such as charged pions that are absorbed by argon nuclei. The algorithm's energy measurement resolutions and fractional biases are presented as functions of particle kinetic energy and number of track hits using samples of stopping secondary charged pions in data collected by the ProtoDUNE-SP detector, and also in a detailed simulation. Additional studies describe the impact of the dE/dx model on energy measurement performance. The method described in this paper to characterize the energy measurement performance can be repeated in any LArTPC experiment using stopping secondary charged pions.
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- 2024
65. Beyond Writing a Summary: Utilizing AI Tools to Enhance Writing Skills
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Hyunsook Youn, Nancy Park, and Ryan Michael Murphy
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Courses: This activity can be used in writing-based (communication) courses across various disciplines including, but not limited to, introduction to writing and rhetoric, business communication, and communication research methods. Objectives: On completion of this activity, students will develop critical reading, thinking, and writing skills as they both write their own summary and then compare it to AI-generated summaries on the same reading. Students will practice making decisions about the practical and ethical use of AI tools for communication, especially regarding inclusion in an academic research project and citation.
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- 2025
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66. Learning with Place as a Catalyst for Action
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Catherine Hamm, Jeanne Marie Iorio, Jayson Cooper, Kylie Smith, Peter Crowcroft, Angela Molloy Murphy, Will Parnell, and Nicola Yelland
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In response to dominant discourses of quality and an over-reliance on humancentric practice, the "Learning with Place" framework emerges as an innovative way to rethink practices, structures, and policies within education and beyond. 'Learning with Place' views the local Place as agentic, recognising Place as inclusive of local First Nations knowledges and stories, histories and the more-than-human (for example, landforms, waterways, animals, insects, flora, and fauna). Through 'Learning with Place', deep relationships with the local Place are generated and these relationships become the catalyst for actions and decision-making regarding caring for/with local Place. This article offers an example of 'Learning with Place' in action through an early childhood teacher education program and shares ways in which the framework can be utilised in multiple contexts and disciplines.
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- 2025
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67. Split-Site Course Design: A Pilot Study on Integrating Traditional and Active Learning Classrooms
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Michael P. A. Murphy, Andrea Phillipson, and Andrew Leger
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Recent years have witnessed the spread of purpose-built active learning classrooms throughout the higher education sector. While these innovative learning spaces are well-suited for a variety of active learning strategies, their lack of a single focal point means they are inconvenient spaces for lecturing. While educational developers often encourage instructors to implement active learning strategies in these classrooms, lectures persist. This article reports the results of a pilot study where course meetings were split between two sites each week: some of the course time took place in a lecture hall and some of the course time took place in an active learning classroom. We suggest that this split-site design offers at least two promising indicators, from the perspectives of both students and instructors: 1) an easier transition compared to a full-active learning classroom course; and 2) availability of active learning classroom time to a larger number of courses. Responding to existing literature on the relationship between lecturing and active learning (classrooms), this article presents the results of student surveys and instructor interviews, and outlines future directions for research in split-site course design.
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- 2025
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68. Language and Mathematics Learning: A Comparative Study of Digital Learning Platforms
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Digital Promise, Empirical Education Inc., Xin Wei, Amanda Wortman, Li Cheng, Neil Heffernan, Cristina Heffernan, April Murphy, Cristina Zepeda, Ben Motz, Harmony Jankowski, and Jeremy Roschelle
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This paper presents a conceptual exploration of how Digital Learning Platforms (DLPs) can be utilized to investigate the impact of language clarity, precision, engagement, and contextual relevance on mathematics learning from word problems. Focusing on three distinct DLPs--ASSISTments/E-TRIALS, MATHia/UpGrade, and Canvas/Terracotta--we propose hypothetical studies aimed at uncovering how nuanced language modifications can enhance mathematical understanding and engagement. While these studies are illustrative in nature, they provide a blueprint for researchers interested in leveraging DLPs for empirical investigation so that future investigators gain a better understanding of the emerging infrastructure for research in DLPs and the opportunities provided by them. In highlighting three distinct implementations of the same core research question, we reveal both commonalities as well as differences in how different educational technologies might build evidence, offering a unique opportunity to advance the field of math education and other education research fields.
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- 2024
69. Obstetric outcomes among rural parturients across US urban and rural hospitals
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Strickland, Courtney L, Tumin, Dmitry, Harris, Alyssa, Murphy, Hannah, and Whiteside, James L
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- 2024
70. The Experience of Teaching in an Active Learning Classroom: A Positive/Negative Perception Study
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Michael P. A. Murphy, Andrea Phillipson, Karalyn E. McRae, and Andrew B. Leger
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"Active learning classrooms" are purpose-built learning spaces designed to facilitate active learning strategies. While sometimes constructed as new rooms, active learning classrooms may also be retrofit from existing learning spaces. The ongoing evaluation of active learning classrooms helps to generate new research insights, pedagogical practices, and refinements for teacher training. While perception studies are well-established as research methods within the evaluation of ALCs, this article provides a novel methodological contribution by applying a positive/negative study framework to an instructor survey distributed in an institution with an established history of evaluating ALCs. We find that this approach enabled new insights into expected findings: that ALCs are best used when expectations are matched to the specifications of the built environment, that low-tech ALCs foster social interaction, and that "shadow zones" in retrofitted rooms may introduce physical barriers to teaching and learning.
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- 2024
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71. The Speaking Proficiency Outcomes of Face-to-Face and Online Intensive Summer LCTL Programs
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Dianna Murphy and Sonya K. Sedivy
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This article is the first large-scale study to document the speaking proficiency outcomes of intensive programs in less commonly taught languages in US higher education. Speaking proficiency was measured by pre- and postprogram ACTFL Oral Proficiency Interviews (N = 484) in 14 languages: Arabic, Bengali, Brazilian Portuguese, Hindi, Indonesian, Kazakh, Persian, Tamil, Thai, Tibetan, Turkish, Urdu, Uyghur, and Uzbek. The intensive programs are usually taught face-to-face but were offered fully online during the COVID-19 pandemic. No significant difference in speaking proficiency outcomes, as measured by the ACTFL OPI, was found between the face-to-face and online formats. Students at all levels of instruction made significant gains in speaking proficiency, with greater gains made by students in Level 1 than at Levels 2-3, and with wide variation within instructional levels. The average speaking proficiency outcomes were Advanced Low (Level 3), Intermediate High (Level 2), and between Intermediate Low and Intermediate Mid (Level 1).
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- 2024
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72. How Important Is Studying Languages for Undergraduate Students and Why (Not) Study Languages?
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Koen Van Gorp, Emily Heidrich Uebel, Felix A. Kronenberg, and Dianna Murphy
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This study examines the value undergraduate students (n = 4458) place on proficiency in languages other than English (LOTEs) in terms of their personal interests, major(s), and career plans. Combining quantitative and qualitative analyses of large-scale survey data, the study further explores the reasons students outline for (not) enrolling in LOTE courses and what would motivate them to enroll in language courses in the future. Results indicate that students attached most value in relation to personal interests, followed by career plans and major. In addition, students' demographics and prior experience with language can also impact their future enrollment decisions. The results suggest that not only should institutions lead the way by emphasizing the importance of learning languages, but also that language programs need to listen to students' voices and help them establish clear links between their academic majors, their future career and study plans as well as their personal interests.
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- 2024
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73. Instructor Mindset Beliefs and Behaviors: How Do Students and Instructors Perceive Them?
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Katherine Muenks, Kathryn M. Kroeper, Elizabeth A. Canning, and Mary C. Murphy
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Advances in growth mindset scholarship now recognize the role of instructors' mindsets in shaping classroom mindset culture. In the present paper, we synthesize the newly developing instructor mindset literature and report on a dataset that includes student (N = 765) and instructor (N = 44) reports of instructor mindset beliefs and behaviors. We organize our paper around four key questions: (1) What teaching behaviors signal instructors' mindset beliefs to students? (2) What teaching behaviors are associated with instructors' mindset beliefs? (3) Do students and instructors in the same classroom agree about instructors' beliefs and behaviors? (4) Where should researchers target interventions aimed at promoting growth mindset cultures? We then discuss three problems that instructors might encounter when trying to create growth mindset cultures--when instructors inconsistently engage in growth mindset behaviors, when instructors unwittingly communicate a fixed mindset to students, and when students fail to notice instructors' growth mindset behaviors--and potential solutions to these problems. We end with implications for instructor-focused interventions, which include both encouraging instructors to engage in growth-focused behaviors and to state clearly why their behaviors communicate a belief in student growth.
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- 2024
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74. Refracting Lecturers' Digital Identity through the Lens of Policy Reform of Technological Universities in Ireland
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Clare Finnegan and Regina Murphy
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The Irish higher education sector is undergoing transformation as many Institutes of Technology (IoTs) become Technology Universities (TUs). This paper aims to explore lecturer identity in higher education in the context of recent contract structure recommendations by the Organisation for Economic Co-operation and Development (OECD) for lecturers in the emerging TU sector. This study is of significant relevance as the OECD recommendations are being used to inform future lecturer contracts. First, theoretical perspectives on identity development are explored, focussing on teacher identity, professionality, professionalism and ideal online teacher identity. Using this theoretical framework, lecturer identity as presented by TU lecturers of education in their public, online biographies is deconstructed. Qualitative, desk-based analysis of these biographies explores (i) lecturers' imagined audience for their online identity; (ii) projected, ideal lecturer identity, including representations of professionality; and (iii) teaching and research values. By aligning lecturer identity portraits to proposed OECD contract structures, the discussion considers how well-positioned TU lecturers are to changes across the IoT/TU sector nationally and implications for the sector.
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- 2024
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75. Exploring the Application of Dialogic Reading Strategies and Mixed Reality Simulations in Supporting Social-Emotional Learning among Young Students in an After-School Setting
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Amy L. Cook, Kristin M. Murphy, Lindsay M. Fallon, Alexis Ervin, Anastasiia Iun, and Anna Whitehouse
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Research supports the use of engaging young students in shared reading opportunities beyond the school setting to scaffold children's social emotional and academic development. This article describes an exploratory mixed-methods case study examining the application of the Storybooks and Social Hooks (SASH) curriculum, which uses dialogic reading strategies and extension/role-play activities to develop SEL among early elementary students in an after-school setting in the USA. Mixed reality (MR) simulation was also used in curriculum delivery to provide participants with additional and more authentic practice of SEL skills. A pre-post mixed-methods longitudinal case study design was employed to explore preliminary outcomes of SASH program delivery with MR simulation on social-emotional development. Direct behavior rating (DBR) was collected across all sessions and phases of study implementation. In addition, interviews with students and caretakers were conducted to explore perceived benefits of the intervention and service outcomes. Findings suggest that dialogic reading with extension/role-play activities is a helpful strategy to develop SEL, and the added use of MR simulation may further aid with scaffolding SEL development in young students. Implications for educational research and practice that involves combining dialogic reading with MR simulation among elementary-aged children to promote SEL are discussed.
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- 2024
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76. Soft Expulsion: What Happens When School-Based Supports Aren't Enough
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Diana Hoffstein-Rahmey, Keri Giordano, Kayla M. Murphy, Rashel Reizin-Friedman, and Amanda Coyne
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Very limited research exists regarding the beliefs and practices of student support teams (SSTs), sometimes called child study teams or IEP teams, in settings with non-expulsion policies for young children with severely challenging behaviors. Previous research examined teacher and administrator beliefs and practices and found that they engage in practices related to soft expulsion (Murphy et al. in Child Youth Serv Rev 158:107441, 2024). Some school psychologists and SST members may also resort to soft expulsion, subtly pushing children out of their schools due to challenging behaviors (Zinsser et al. in Rev Educ Res 92(5):743-785, 2022). This study utilized an anonymous, online, self-report measure to investigate the practices and beliefs of SST members in early childhood education settings with non-expulsion policies. Participants included 108 school-based service providers in one state. The majority identified as school psychologists, held a Master's degree, had between 1 and 5 years of experience, and worked 36-40 h per week. Results showed that most participants said they had the supports to meet the needs of children with severely challenging behaviors, yet most had worked with a child whose behaviors they were unable to manage. Our examination also uncovered indications of soft expulsion practices and a general lack of knowledge about existing non-expulsion policies. The implications arising from these beliefs and practices are examined and discussed.
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- 2024
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77. Multilevel Factors of School-Based Mental Health Service Utilization among Middle and High School Students
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Jennifer Murphy, Youngmi Kim, and Kristen Kerr
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Evidence suggests that youth progressively experience mental health needs and discover mental health symptoms for the first time in adolescence. Schools have come to the forefront of providing mental health services, as adolescents spend most of their day in the academic setting. The current study aimed to examine individual and school-level factors related to school-based mental health service use. This study employed data from the National Longitudinal Study of Adolescent to Adult Health, sampling students between 12 and 17 years old across 172 schools (N = 14,464). The dependent variable was use of school-based mental health services (SMHS) in the past year. Individual-level predictors included sociodemographic characteristics, enabling factors, and need. School-level factors were then included. We conducted a multilevel logistic regression model clustering at the school level. The study found that approximately 11% of variation in SMHS utilization is explained at the school-level. The odds of SMHS use was significantly associated with anxiety, depressive symptoms, and risk-taking behaviors. The odds of SMHS was higher for females, Black compared to White students, and public assistance recipients. SMHS use was negatively associated with school connectedness. The racial breakdown of student enrollment and location of services were significant factors that predicted service use. This study is among the first empirical studies providing important evidence regarding individual and school-level predictors of SMHS utilization. The study has implications for the continued need for school-based mental health professionals and school institutions' efforts to meet students' mental health needs and increase their access to services.
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- 2024
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78. Access to Senior Secondary Science and Mathematics: Examining the Evidence for Stratification in an Australian School System
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Jenny Dean, Philip Roberts, and Steve Murphy
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This research investigates access to senior school science and mathematics subjects offered in the final year of secondary schooling. Using data from the most populous Australian state of New South Wales, we examine whether stratification occurs in access to science and mathematics curricula. We find that the opportunity to study these subjects differs by key school characteristics, including location, socioeconomic composition and school sector. We find that while some science subjects and entry level mathematics are offered in most schools, substantial inequalities exist in access to the most advanced level of mathematics and chemistry. School location, socioeconomic composition, enrolment size and the availability of teachers predict the probability of whether a school offers the least and most advanced science and mathematics subjects. The findings highlight that stratification in curricula offerings occurs systemically and may intensify educational inequalities.
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- 2024
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79. Age-Related Differences in Metacognitive Reactivity in Younger and Older Adults
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Dillon H. Murphy, Matthew G. Rhodes, and Alan D. Castel
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When we monitor our learning, often measured via judgments of learning (JOLs), this metacognitive process can change what is remembered. For example, prior work has demonstrated that making JOLs enhances memory for related, but not unrelated, word pairs in younger adults. In the current study, we examined potential age-related differences in metacognitive reactivity. Younger and older adults studied lists of related and unrelated word pairs to remember for a later cued recall test where they would be presented with one of the words from the pair and be asked to recall its associate. Additionally, participants either made a JOL for each pair or had an inter-stimulus interval of equal duration as the JOL period. Results revealed that while making metacognitive judgments did not significantly affect memory in younger adults (i.e., no reactivity), this procedure impaired memory in older adults (i.e., negative reactivity), particularly for unrelated word pairs. Specifically, older adults demonstrated better cued recall when each word was followed by an inter-stimulus interval than when asked to predict the likelihood of remembering each word during the study phase. This may be a consequence of JOLs increasing task demands/cognitive load, which could reduce the elaborative encoding of associations between word pairs in older adults, but older adults' preserved or even enhanced semantic memory may mask negative reactivity for related word pairs. Future work is needed to better understand the mechanisms contributing to the reactivity effects in younger and older adults for different types of to-be-remembered information.
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- 2024
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80. Feeling Uprooted? Examining the Relevance of Homesickness and Fear of Missing Out for Adolescents in a Residential Program
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Joshua J. Underwood, Mackenzie B. Murphy, Christopher T. Barry, and Samantha L. Radcliffe
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Background: Fear of missing out (FoMO) and homesickness have been associated with a variety of negative psychosocial outcomes; however, they have rarely been studied together or with adolescents in residential settings. Objective: This study examined the potential associations of FoMO and homesickness with program outcomes in a sample of adolescents attending a military-style residential program. The residential treatment context inherently involves removal and isolation from an individual's typical living arrangements. Methods: Data were collected from 185 participants (aged 16-18) at three time points (i.e., 2 weeks after entry into the 19-week program; 9 weeks into the program; at week 18 of the program). RESULTS: Overall, FoMO and homesickness declined from initial assessment to midway through the program but rebounded just prior to exit from the program. FoMO and homesickness showed no direct correlations with participant outcomes, although both showed patterns of correlation demonstrating poor adjustment (e.g., low emotion regulation, high loneliness). Decreases in FoMO and homesickness during the program were positively correlated with distress tolerance. Conclusions: Given the negative implications of experiencing FoMO and homesickness, adolescents at risk for emotional distress tolerance may need additional support when initiating participation in residential programs.
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- 2024
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81. Reducing radiation exposure in pediatric cervical spine imaging for trauma: a multi-disciplinary quality improvement initiative.
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Yu, Nina, Kohler, Jonathan, Grether-Jones, Kendra, Murphy, Maureen, and Zwienenberg, Marike
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Imaging ,Pediatric ,Quality improvement ,Trauma ,Humans ,Female ,Male ,Child ,Child ,Preschool ,Tomography ,X-Ray Computed ,Quality Improvement ,Cervical Vertebrae ,Retrospective Studies ,Infant ,Adolescent ,Radiation Exposure ,Spinal Injuries ,Guideline Adherence ,Infant ,Newborn ,Trauma Centers - Abstract
PURPOSE: Pediatric cervical spine injury (PCSI) can result in devastating neurologic disability. While computed tomography (CT) imaging is both sensitive and specific in detecting clinically significant injuries, indiscriminate utilization can lead to excessive ionizing radiation exposure. A routine institutional audit revealed CTs were inappropriately obtained 54% of the time. This study evaluates the effects of an updated protocol to reduce radiation exposure in pediatric trauma patients. METHODS: Data were retrospectively analyzed from a pediatric level 1 trauma center from 2021 to 2022. The data were divided into two cohorts, pre-implementation (2021) and post-implementation (2022). Inclusion criteria were patients 0-14 years old with a Glasgow Coma Scale (GCS) ranging 9-15. Outside-hospital transfers were excluded. The primary study endpoints were guideline compliance and CT utilization. RESULTS: A total of 82 subjects were enrolled in this study. In 2021, there were 38 subjects (female/male 15/23, mean age 5.9 years old) with an average GCS of 13.6. In 2022, there were 44 subjects (female/male 19/25, mean age 5.2 years old) with an average GCS of 14.0. In 2021, the overall protocol adherence rate was 81.6%, and post-implementation in 2022, compliance was 93.2% (p = 0.109). Following implementation, the rate of inappropriate (protocol non-adherent CT) use decreased from 58.6 to 6.8% (p
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- 2025
82. Caregiver Global Impression Observations from EMBARK: A Phase 3 Study Evaluating Delandistrogene Moxeparvovec in Ambulatory Patients with Duchenne Muscular Dystrophy.
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Mcdonald, Craig, Elkins, Jacob, Dharmarajan, Sai, Gooch, Katherine, Ciobanu, Teofil, Lansdall, Claire, Murphy, Alexander, McDougall, Fiona, Mercuri, Eugenio, and Audhya, Ivana
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Caregiver ,Delandistrogene moxeparvovec ,Duchenne muscular dystrophy ,Gene therapy ,Global Impressions scale - Abstract
INTRODUCTION: Duchenne muscular dystrophy (DMD) is a rare, progressive, debilitating neuromuscular disease. The early childhood onset and debilitating nature of the disease necessitate decades of caretaking for most patients. Caregivers have a critical role in evaluating patients physical functioning and/or response to treatment. Using DMD-specific caregiver-reported scales, the impact of delandistrogene moxeparvovec gene therapy on caregivers perceived change in patient disease status or severity was evaluated using the Caregiver Global Impression of Change and Severity (CaGI-C and CaGI-S, respectively). METHODS: In the Phase 3 randomized, double-blind, placebo-controlled trial (EMBARK; NCT05096221), the CaGI-C at week 52 and change from baseline to week 52 in CaGI-S were evaluated in a post hoc analysis. The CaGI-C assesses caregivers impressions of change in DMD symptoms, physical ability, ability to perform daily activities, and overall health. The CaGI-S evaluates current severity of DMD symptoms, physical ability, ability to perform activities of daily living, and overall health. Data were evaluated using multi-domain responder index (MDRI) and ordinal regression analyses. RESULTS: MDRI analyses across all four CaGI-C items yielded a treatment difference of 1.7 (95% confidence interval [CI]: 0.90-2.5) favoring delandistrogene moxeparvovec; a treatment difference of 1.1 (95% CI 0.30-1.9) was observed for the CaGI-S favoring delandistrogene moxeparvovec. After adjusting for age, ordinal regression analysis showed a nominally significant increase in the odds of achieving a better rating for delandistrogene moxeparvovec-treated patients on all four CaGI-C items (≥ 3.8-fold increase). After adjusting for baseline severity and age, ordinal regression analysis showed a nominally significant increase in the odds of improvement on all four CaGI-S items (≥ 2.2-fold increase). CONCLUSION: These exploratory findings captured by caregiver-reported outcomes add to the totality of evidence that supports the clinical benefits of delandistrogene moxeparvovec for patients with DMD. TRIAL REGISTRATION NUMBER: ClinicalTrials.gov identifier, NCT05096221.
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- 2025
83. Ethnic and racial differences in children and young people with respiratory and neurological post-acute sequelae of SARS-CoV-2: an electronic health record-based cohort study from the RECOVER Initiative.
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Rao, Suchitra, Azuero-Dajud, Rodrigo, Lorman, Vitaly, Landeo-Gutierrez, Jeremy, Rhee, Kyung, Ryu, Julie, Kim, C, Carmilani, Megan, Gross, Rachel, Mohandas, Sindhu, Suresh, Srinivasan, Bailey, L, Castro, Victor, Senathirajah, Yalini, Esquenazi-Karonika, Shari, Murphy, Shawn, Caddle, Steve, Kleinman, Lawrence, Castro-Baucom, Leah, Oliveira, Carlos, Klein, Jonathan, Chung, Alicia, Cowell, Lindsay, Madlock-Brown, Charisse, Geary, Carol, Sills, Marion, Thorpe, Lorna, Szmuszkovicz, Jacqueline, and Tantisira, Kelan
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Chronic COVID-19 syndrome ,Ethnicity ,Late sequelae of COVID-19 ,Long COVID ,Long-haul COVID ,Long-term COVID-19 ,PCORnet ,PEDSnet ,Post-COVID condition ,Post-COVID syndrome ,Post-acute COVID-19 ,Post-acute sequelae of SARS-CoV-2 infection ,Race ,Social determinants of health - Abstract
BACKGROUND: Children from racial and ethnic minority groups are at greater risk for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, but it is unclear whether they have increased risk for post-acute sequelae of SARS-CoV-2 (PASC). Our objectives were to assess whether the risk of respiratory and neurologic PASC differs by race/ethnicity and social drivers of health. METHODS: We conducted a retrospective cohort study of individuals
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- 2025
84. Whats in a name? Memory NK cells for cancer immunotherapy.
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Judge, Sean, Purl, Megan, Murphy, William, and Canter, Robert
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Adaptive ,Adoptive cell therapy - ACT ,Immunotherapy ,Memory ,Natural killer - NK ,Humans ,Killer Cells ,Natural ,Neoplasms ,Immunologic Memory ,Immunotherapy ,Animals - Abstract
The discovery that natural killer (NK) cells can retain features of memory from previous stimulation and pathogen exposure was a landmark advance highlighting one of many ways in which NK cells of the innate immune system resemble T cells of the adaptive immune system. This ability to remember prior stimulation to bring about enhanced protection of the host sparked significant excitement regarding potential therapeutic applications. Yet, how closely the features of naïve and memory NK cells recapitulate those of T cells remains unclear. Nonetheless, despite unresolved questions about the immunobiology of naïve and memory NK cells, the application of memory NK cells to the clinic for cancer and other indications has gathered steam to meet the unmet need for novel immunotherapies. Recent work from Arellano-Ballestero et al highlights this evolving field and the current state of the art with memory NK cells. Application of these cells to the clinic is progressing with promising results, but important questions remain about the essential molecular, phenotypic, and functional characteristics that define a memory NK cell.
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- 2025
85. An Enigmatic Wild Passerine Mortality Event in the Eastern United States.
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Greening, Sabrina, Ellis, Julie, Lewis, Nicole, Needle, David, Tato, Cristina, Knowles, Susan, Shearn-Bochsler, Valerie, Miller, Jaimie, Grear, Daniel, Lorch, Jeffrey, Blehert, David, Burrell, Caitlin, Murphy, Lisa, Miller, Erica, Ogbunugafor, C, Ayala, Andrea, Thomas, W, Sevigny, Joseph, Gordon, Lawrence, Baillargeon, Tessa, Mwakibete, Lusajo, Kirchgessner, Megan, Casey, Christine, Barton, Ethan, Yabsley, Michael, Anis, Eman, Gagne, Roderick, Klein, Patrice, Driscoll, Cindy, Sykes, Chelsea, Poppenga, Robert, and Nemeth, Nicole
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conjunctivitis ,diagnostic evaluation ,mass mortality ,passerines ,songbird ,wildlife investigation - Abstract
The ability to rapidly respond to wildlife health events is essential. However, such events are often unpredictable, especially with anthropogenic disturbances and climate-related environmental changes driving unforeseen threats. Many events also are short-lived and go undocumented, making it difficult to draw on lessons learned from past investigations. We report on the response to a mortality event observed predominantly in wild passerines in the eastern United States. The event began in May 2021 when wildlife rehabilitators and private citizens reported large numbers of sick and dead juvenile birds, mostly presenting as single cases with neurologic signs and/or ocular and periocular lesions. Early efforts by rehabilitators, veterinarians, state and federal wildlife agencies, and universities helped gather public reports and fuel rapid responses by government agencies. Collective efforts included live bird and carcass collections; submission to diagnostic laboratories and evaluation; information sharing; and coordinated messaging to stakeholders and interested parties. Extensive diagnostic evaluations failed to identify a causative pathogen or other etiology, although congruent results across laboratories have helped drive further investigation into alternative causes, such as nutritional deficiencies. This report highlights the strengths of a multi-agency, interdisciplinary investigation while exposing the need for an operational framework with approaches and resources dedicated to wildlife health.
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- 2025
86. Bridging the Gap on Data and Analysis for Distribution System Planning: Information That Utilities Can Provide Regulators, State Energy Offices and Other Stakeholders
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Murphy, Sean, Schwartz, Lisa C, Pereira, Guillermo, and Davis, Cody
- Abstract
Electric utilities conduct planning annually to ensure their distribution system meets technical standards, policies, and regulations; addresses forecasted grid conditions; satisfies customer needs; and advances utility priorities. The plan identifies grid deficiencies, analyzes potential solutions, and prioritizes capital investments and other expenditures. About 20 U.S. states and jurisdictions require regulated utilities to file some type of distribution system plan with the public utility commission for review. Requirements for sharing distribution system data and analyses vary widely, from few specific requirements to a detailed list of information that must be provided.While utilities conduct extensive analysis to develop distribution system plans, in most jurisdictions regulators and stakeholders do not know what data are available and how the utility uses the data in planning and investing. This report aims to bridge the gap by increasing understanding of the types of data and analyses utilities employ to develop distribution system plans and how the information affects their decision-making. The report describes information that states and stakeholders can ask for related to 11 data categories:-Forecasting loads and distributed energy resources (DERs)-Scenario analysis-Worst-performing circuits-Asset management strategy-Hosting capacity analysis-Value of DERs-Grid needs assessment-Cost-effectiveness framework for investments-Distribution system investment strategy and implementation-Geotargeted programs-Non-wires alternatives procurement
- Published
- 2025
87. Predictive equation derived from 6,497 doubly labelled water measurements enables the detection of erroneous self-reported energy intake.
- Author
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Bajunaid, Rania, Niu, Chaoqun, Hambly, Catherine, Liu, Zongfang, Yamada, Yosuke, Aleman-Mateo, Heliodoro, Anderson, Liam, Arab, Lenore, Baddou, Issad, Bandini, Linda, Bedu-Addo, Kweku, Blaak, Ellen, Bouten, Carlijn, Brage, Soren, Buchowski, Maciej, Butte, Nancy, Camps, Stefan, Casper, Regina, Close, Graeme, Cooper, Jamie, Cooper, Richard, Das, Sai, Davies, Peter, Dabare, Prasangi, Dugas, Lara, Eaton, Simon, Ekelund, Ulf, Entringer, Sonja, Forrester, Terrence, Fudge, Barry, Gillingham, Melanie, Goris, Annelies, Gurven, Michael, El Hamdouchi, Asmaa, Haisma, Hinke, Hoffman, Daniel, Hoos, Marije, Hu, Sumei, Joonas, Noorjehan, Joosen, Annemiek, Katzmarzyk, Peter, Kimura, Misaka, Kraus, William, Kriengsinyos, Wantanee, Kuriyan, Rebecca, Kushner, Robert, Lambert, Estelle, Lanerolle, Pulani, Larsson, Christel, Leonard, William, Lessan, Nader, Löf, Marie, Martin, Corby, Matsiko, Eric, Medin, Anine, Morehen, James, Morton, James, Must, Aviva, Neuhouser, Marian, Nicklas, Theresa, Nyström, Christine, Ojiambo, Robert, Pietiläinen, Kirsi, Pitsiladis, Yannis, Plange-Rhule, Jacob, Plasqui, Guy, Prentice, Ross, Racette, Susan, Raichlen, David, Ravussin, Eric, Redman, Leanne, Reilly, John, Reynolds, Rebecca, Roberts, Susan, Samaranayakem, Dulani, Sardinha, Luis, Silva, Analiza, Sjödin, Anders, Stamatiou, Marina, Stice, Eric, Urlacher, Samuel, Van Etten, Ludo, van Mil, Edgar, Wilson, George, Yanovski, Jack, Yoshida, Tsukasa, Zhang, Xueying, Murphy-Alford, Alexia, Sinha, Srishti, Loechl, Cornelia, Luke, Amy, Pontzer, Herman, Rood, Jennifer, Sagayama, Hiroyuki, Schoeller, Dale, Westerterp, Klaas, Wong, William, and Speakman, John
- Subjects
Humans ,Energy Intake ,Aged ,Adolescent ,Adult ,Female ,Child ,Middle Aged ,Male ,Child ,Preschool ,Aged ,80 and over ,Young Adult ,Self Report ,Nutrition Surveys ,Energy Metabolism ,Diet ,Body Mass Index ,Water - Abstract
Nutritional epidemiology aims to link dietary exposures to chronic disease, but the instruments for evaluating dietary intake are inaccurate. One way to identify unreliable data and the sources of errors is to compare estimated intakes with the total energy expenditure (TEE). In this study, we used the International Atomic Energy Agency Doubly Labeled Water Database to derive a predictive equation for TEE using 6,497 measures of TEE in individuals aged 4 to 96 years. The resultant regression equation predicts expected TEE from easily acquired variables, such as body weight, age and sex, with 95% predictive limits that can be used to screen for misreporting by participants in dietary studies. We applied the equation to two large datasets (National Diet and Nutrition Survey and National Health and Nutrition Examination Survey) and found that the level of misreporting was >50%. The macronutrient composition from dietary reports in these studies was systematically biased as the level of misreporting increased, leading to potentially spurious associations between diet components and body mass index.
- Published
- 2025
88. Advanced Restriction Imaging and Reconstruction Technology for Prostate Magnetic Resonance Imaging (ART-Pro): A Study Protocol for a Multicenter, Multinational Trial Evaluating Biparametric Magnetic Resonance Imaging and Advanced, Quantitative Diffusion Magnetic Resonance Imaging for the Detection of Prostate Cancer.
- Author
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Baxter, Madison, Conlin, Christopher, Bagrodia, Aditya, Barrett, Tristan, Bartsch, Hauke, Brau, Anja, Cooperberg, Matthew, Dale, Anders, Guidon, Arnaud, Hahn, Michael, Harisinghani, Mukesh, Javier-DesLoges, Juan, Kamran, Sophia, Kane, Christopher, Kuperman, Joshua, Margolis, Daniel, Murphy, Paul, Nakrour, Nabih, Ohliger, Michael, Rakow-Penner, Rebecca, Shabaik, Ahmed, Simko, Jeffry, Tempany, Clare, Wehrli, Natasha, Woolen, Sean, Zou, Jingjing, and Seibert, Tyler
- Subjects
Biparametric magnetic resonance imaging ,Clinical trial ,Multiparametric magnetic resonance imaging ,Prostate cancer ,Restriction Spectrum Imaging ,Restriction Spectrum Imaging restriction score - Abstract
Multiparametric magnetic resonance imaging (mpMRI) is strongly recommended by current clinical guidelines for improved detection of clinically significant prostate cancer (csPCa). However, the major limitations are the need for intravenous (IV) contrast and dependence on reader expertise. Efforts to address these issues include use of biparametric magnetic resonance imaging (bpMRI) and advanced, quantitative magnetic resonance imaging (MRI) techniques. One such advanced technique is the Restriction Spectrum Imaging restriction score (RSIrs), an imaging biomarker that has been shown to improve quantitative accuracy of patient-level csPCa detection. Advanced Restriction imaging and reconstruction Technology for Prostate MRI (ART-Pro) is a multisite, multinational trial that aims to evaluate whether IV contrast can be avoided in the setting of standardized, state-of-the-art image acquisition, with or without addition of RSIrs. Additionally, RSIrs will be evaluated as a stand-alone, quantitative, objective biomarker. ART-Pro will be conducted in two stages and will include a total of 500 patients referred for multiparametric prostate MRI with a clinical suspicion of prostate cancer at the participating sites. ART-Pro-1 will evaluate bpMRI, mpMRI, and RSIrs on the accuracy of expert radiologists detection of csPCa and will evaluate RSIrs as a stand-alone, quantitative, objective biomarker. ART-Pro-2 will evaluate the same MRI techniques on the accuracy of nonexpert radiologists detection of csPCa, and findings will be evaluated against the expertly created dataset from ART-Pro-1. The primary endpoint is to evaluate whether bpMRI is noninferior to mpMRI among expert (ART-Pro-1) and nonexpert (ART-Pro-2) radiologists for the detection of grade group ≥2 csPCa. This trial is registered in the US National Library of Medicine Trial Registry (NCT number: NCT06579417) at ClinicalTrials.gov. Patient accrual at the first site (UC San Diego) began in December 2023. Initial results are anticipated by the end of 2026.
- Published
- 2025
89. Purple Rain: Temperamental Politics and Budgets in Arizona
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Goshert, Max, Murphy, Janica, Amin, Samira, Abouelenin, Mo, Chisholm, Amber, Khalkhali, Matthew, Miramontes, Jaden, Yslava Molina, Brian, Lee, Wanting, Schneider, Jaden, Vera, Tawanda, and Iben, Cati
- Subjects
State Budgeting ,Arizona - Abstract
Arizona’s evolving political landscape has become a key factor in its fiscal outlook. Once a solid Republican stronghold, the state has shifted to swing status, as seen in President Joe Biden's narrow 0.3% margin win in the 2020 election and a closely divided state legislature. Strong economic growth in prior years led to FY23 General Fund revenues being revised upwards from $15.9 billion to $17.9 billion. Despite this, declining tax revenues and increased spending, particularly on a universal school voucher program, created a projected $1.71 billion deficit for FY25. The state's Republican-led legislature implemented a 2.5% flat income tax and expanded school vouchers, significantly impacting revenue. To address the deficit, the FY25 budget, finalized at $16.8 billion, included cuts to many programs, most notably a $430 million reduction in the Arizona Water Infrastructure and Financing Authority. The political status quo remained consistent after the 2024 election, where Republicans won a marginal gain in both chambers of the state legislature, Democrats kept control of the U.S. Senate seat up for reelection, and the U.S. House seats remained at 6–3 for Republicans and Democrats, respectively. This report examines the fiscal trajectory, proposed tax policy changes, and political state driving Arizona’s FY25 budget negotiations.
- Published
- 2025
90. Polygenic score distribution differences across European ancestry populations: implications for breast cancer risk prediction.
- Author
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Yiangou, Kristia, Mavaddat, Nasim, Dennis, Joe, Zanti, Maria, Wang, Qin, Bolla, Manjeet, Abubakar, Mustapha, Ahearn, Thomas, Andrulis, Irene, Anton-Culver, Hoda, Antonenkova, Natalia, Arndt, Volker, Aronson, Kristan, Augustinsson, Annelie, Baten, Adinda, Behrens, Sabine, Bermisheva, Marina, de Gonzalez, Amy, Białkowska, Katarzyna, Boddicker, Nicholas, Bodelon, Clara, Bogdanova, Natalia, Bojesen, Stig, Brantley, Kristen, Brauch, Hiltrud, Brenner, Hermann, Camp, Nicola, Canzian, Federico, Castelao, Jose, Cessna, Melissa, Chang-Claude, Jenny, Chenevix-Trench, Georgia, Chung, Wendy, Colonna, Sarah, Couch, Fergus, Cox, Angela, Cross, Simon, Czene, Kamila, Daly, Mary, Devilee, Peter, Dörk, Thilo, Dunning, Alison, Eccles, Diana, Eliassen, A, Engel, Christoph, Eriksson, Mikael, Evans, D, Fasching, Peter, Fletcher, Olivia, Flyger, Henrik, Fritschi, Lin, Gago-Dominguez, Manuela, Gentry-Maharaj, Aleksandra, González-Neira, Anna, Guénel, Pascal, Hahnen, Eric, Haiman, Christopher, Hamann, Ute, Hartikainen, Jaana, Ho, Vikki, Hodge, James, Hollestelle, Antoinette, Honisch, Ellen, Hooning, Maartje, Hoppe, Reiner, Hopper, John, Howell, Sacha, Howell, Anthony, Jakovchevska, Simona, Jakubowska, Anna, Jernström, Helena, Johnson, Nichola, Kaaks, Rudolf, Khusnutdinova, Elza, Kitahara, Cari, Koutros, Stella, Kristensen, Vessela, Lacey, James, Lambrechts, Diether, Lejbkowicz, Flavio, Lindblom, Annika, Lush, Michael, Mannermaa, Arto, Mavroudis, Dimitrios, Menon, Usha, Murphy, Rachel, Nevanlinna, Heli, Obi, Nadia, Offit, Kenneth, Park-Simon, Tjoung-Won, Patel, Alpa, Peng, Cheng, Peterlongo, Paolo, Pita, Guillermo, Plaseska-Karanfilska, Dijana, Pylkäs, Katri, Radice, Paolo, Rashid, Muhammad, Rennert, Gad, and Roberts, Eleanor
- Subjects
Breast cancer ,Polygenic risk scores ,Risk calibration ,Risk prediction ,Humans ,Female ,Breast Neoplasms ,Genetic Predisposition to Disease ,Multifactorial Inheritance ,White People ,Risk Assessment ,Risk Factors ,Europe ,Polymorphism ,Single Nucleotide ,Genome-Wide Association Study ,Middle Aged ,Genotype - Abstract
BACKGROUND: The 313-variant polygenic risk score (PRS313) provides a promising tool for clinical breast cancer risk prediction. However, evaluation of the PRS313 across different European populations which could influence risk estimation has not been performed. METHODS: We explored the distribution of PRS313 across European populations using genotype data from 94,072 females without breast cancer diagnosis, of European-ancestry from 21 countries participating in the Breast Cancer Association Consortium (BCAC) and 223,316 females without breast cancer diagnosis from the UK Biobank. The mean PRS was calculated by country in the BCAC dataset and by country of birth in the UK Biobank. We explored different approaches to reduce the observed heterogeneity in the mean PRS across the countries, and investigated the implications of the distribution variability in risk prediction. RESULTS: The mean PRS313 differed markedly across European countries, being highest in individuals from Greece and Italy and lowest in individuals from Ireland. Using the overall European PRS313 distribution to define risk categories, leads to overestimation and underestimation of risk in some individuals from these countries. Adjustment for principal components explained most of the observed heterogeneity in the mean PRS. The mean estimates derived when using an empirical Bayes approach were similar to the predicted means after principal component adjustment. CONCLUSIONS: Our results demonstrate that PRS distribution differs even within European ancestry populations leading to underestimation or overestimation of risk in specific European countries, which could potentially influence clinical management of some individuals if is not appropriately accounted for. Population-specific PRS distributions may be used in breast cancer risk estimation to ensure predicted risks are correctly calibrated across risk categories.
- Published
- 2024
91. State Requirements for Electric Distribution System Planning
- Author
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Schwartz, Lisa C, Frick, Natalie Mims, Murphy, Sean, Pereira, Guillermo, Shipley, Jessica, and Schellenberg, Josh A
- Abstract
Utilities have conducted distribution planning since they first began building and operating electricity systems. But filing these plans for regulatory and stakeholder review is a relatively recent phenomenon. This report summarizes legislative and regulatory requirements for regulated electric utilities to file some type of distribution system plan in 20 U.S. jurisdictions. Some plans focus on expedited cost recovery for certain types of distribution system improvements; other plans focus on investments for grid modernization or distributed energy resources. Increasingly, states are adopting requirements for Integrated Distribution Plans. Such plans provide holistic grid investment strategies that address state and local policies and increasing complexity at the grid edge. The report covers the following topics for distribution system plans, highlighting advanced practices:-State goals and objectives-Procedural requirements-Forecasting loads and distributed energy resources-Hosting capacity analysis-Baseline information requirements-Grid modernization strategy-Grid needs assessment-Non-wires solutions-Reliability and resilience analyses-Stakeholder engagement-Equity-Pilots-Coordination with other planning processes The report includes links to legislation; regulatory requirements, proceedings, and orders; and filed utility plans. The U.S. Department of Energy’s Office of Electricity provided funding support.
- Published
- 2024
92. BOTS: Batch Bayesian Optimization of Extended Thompson Sampling for Severely Episode-Limited RL Settings
- Author
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Karine, Karine, Murphy, Susan A., and Marlin, Benjamin M.
- Subjects
Computer Science - Machine Learning ,Computer Science - Artificial Intelligence ,Statistics - Machine Learning - Abstract
In settings where the application of reinforcement learning (RL) requires running real-world trials, including the optimization of adaptive health interventions, the number of episodes available for learning can be severely limited due to cost or time constraints. In this setting, the bias-variance trade-off of contextual bandit methods can be significantly better than that of more complex full RL methods. However, Thompson sampling bandits are limited to selecting actions based on distributions of immediate rewards. In this paper, we extend the linear Thompson sampling bandit to select actions based on a state-action utility function consisting of the Thompson sampler's estimate of the expected immediate reward combined with an action bias term. We use batch Bayesian optimization over episodes to learn the action bias terms with the goal of maximizing the expected return of the extended Thompson sampler. The proposed approach is able to learn optimal policies for a strictly broader class of Markov decision processes (MDPs) than standard Thompson sampling. Using an adaptive intervention simulation environment that captures key aspects of behavioral dynamics, we show that the proposed method can significantly out-perform standard Thompson sampling in terms of total return, while requiring significantly fewer episodes than standard value function and policy gradient methods., Comment: Accepted at NeurIPS 2024 Workshop on Bayesian Decision-making and Uncertainty
- Published
- 2024
93. WiReSens Toolkit: An Open-source Platform towards Accessible Wireless Tactile Sensing
- Author
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Murphy, Devin, Zhu, Junyi, Liang, Paul Pu, Matusik, Wojciech, and Luo, Yiyue
- Subjects
Computer Science - Human-Computer Interaction - Abstract
Tactile sensors present a powerful means of capturing, analyzing, and augmenting human-environment interactions. Accelerated by advancements in design and manufacturing, resistive matrix-based sensing has emerged as a promising method for developing scalable and robust tactile sensors. However, the development of portable, adaptive, and long lasting resistive tactile sensing systems remains a challenge. To address this, we introduce WiReSens Toolkit. Our platform provides open-source hardware and software libraries to configure multi-sender, power-efficient, and adaptive wireless tactile sensing systems in as fast as ten minutes. We demonstrate our platform's flexibility by using it to prototype several applications such as musical gloves, gait monitoring shoe soles, and IoT-enabled smart home systems.
- Published
- 2024
94. Towards a Mechanistic Explanation of Diffusion Model Generalization
- Author
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Niedoba, Matthew, Zwartsenberg, Berend, Murphy, Kevin, and Wood, Frank
- Subjects
Computer Science - Machine Learning ,Computer Science - Artificial Intelligence ,Computer Science - Computer Vision and Pattern Recognition - Abstract
We propose a mechanism for diffusion generalization based on local denoising operations. Through analysis of network and empirical denoisers, we identify local inductive biases in diffusion models. We demonstrate that local denoising operations can be used to approximate the optimal diffusion denoiser. Using a collection of patch-based, local empirical denoisers, we construct a denoiser which approximates the generalization behaviour of diffusion model denoisers over forward and reverse diffusion processes., Comment: 13 pages, 15 figures. Accepted to NeurIPS 2024 Workshop on Attributing Model Behavior at Scale
- Published
- 2024
95. Surveying the space of descriptions of a composite system with machine learning
- Author
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Murphy, Kieran A., Zhang, Yujing, and Bassett, Dani S.
- Subjects
Computer Science - Information Theory ,Computer Science - Machine Learning ,Physics - Data Analysis, Statistics and Probability - Abstract
Multivariate information theory provides a general and principled framework for understanding how the components of a complex system are connected. Existing analyses are coarse in nature -- built up from characterizations of discrete subsystems -- and can be computationally prohibitive. In this work, we propose to study the continuous space of possible descriptions of a composite system as a window into its organizational structure. A description consists of specific information conveyed about each of the components, and the space of possible descriptions is equivalent to the space of lossy compression schemes of the components. We introduce a machine learning framework to optimize descriptions that extremize key information theoretic quantities used to characterize organization, such as total correlation and O-information. Through case studies on spin systems, Sudoku boards, and letter sequences from natural language, we identify extremal descriptions that reveal how system-wide variation emerges from individual components. By integrating machine learning into a fine-grained information theoretic analysis of composite random variables, our framework opens a new avenues for probing the structure of real-world complex systems., Comment: Code here: https://github.com/murphyka/description_space
- Published
- 2024
96. OrCAS: Origins, Compositions, and Atmospheres of Sub-neptunes. I. Survey Definition
- Author
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Crossfield, Ian J. M., Polanski, Alex S., Robertson, Paul, Murphy, Joseph Akana, Turtelboom, Emma V., Luque, Rafael, Beatty, Thomas, Daylan, Tansu, Isaacson, Howard, Brande, Jonathan, Kreidberg, Laura, Batalha, Natalie M., Huber, Daniel, Rhem, Maleah, Dressing, Courtney, Kane, Stephen R., Bossett, Malik, Gagnebin, Anna, Kroft, Maxwell A., Premnath, Pranav H., Rogers, Claire J., Collins, Karen A., Latham, David W., Watkins, Cristilyn N., Ciardi, David R., Howell, Steve B., Savel, Arjun B., Berlind, Perry, Calkins, Michael L., Esquerdo, Gilbert A., Mink, Jessica, Clark, Catherine A., Lund, Michael B., Matson, Rachel A., Everett, Mark E., Schlieder, Joshua E., Matthews, Elisabeth C., Giacalone, Steven, Barclay, Thomas, Zambelli, Roberto, Plavchan, Peter, Ellingson, Taylor, Bowen, Michael, Srdoc, Gregor, McLeod, Kim K., Schwarz, Richard P., Barkaoui, Khalid, Kamler, Jacob, Murgas, Felipe, Palle, Enric, Narita, Norio, Fukui, Akihiko, Relles, Howard M., Bieryla, Allyson, Girardin, Eric, Massey, Bob, Stockdale, Chris, Lewin, Pablo, Papini, Riccardo, Guerra, Pere, Conti, Dennis M., Yalcinkaya, Selcuk, Basturk, Ozgur, and Mourad, Ghachoui
- Subjects
Astrophysics - Earth and Planetary Astrophysics - Abstract
Sub-Neptunes - volatile-rich exoplanets smaller than Neptune - are intrinsically the most common type of planet known. However, the formation and nature of these objects, as well as the distinctions between sub-classes (if any), remain unclear. Two powerful tools to tease out the secrets of these worlds are measurements of (i) atmospheric composition and structure revealed by transit and/or eclipse spectroscopy, and (ii) mass, radius, and density revealed by transit photometry and Doppler spectroscopy. Here we present OrCAS, a survey to better elucidate the origins, compositions, and atmospheres of sub-Neptunes. This radial velocity survey uses a repeatable, quantifiable metric to select targets suitable for subsequent transmission spectroscopy and address key science themes about the atmospheric & internal compositions and architectures of these systems. Our survey targets 26 systems with transiting sub-Neptune planet candidates, with the overarching goal of increasing the sample of such planets suitable for subsequent atmospheric characterization. This paper lays out our survey's science goals, defines our target prioritization metric, and performs light-curve fits and statistical validation using existing TESS photometry and ground-based follow-up observations. Our survey serves to continue expanding the sample of small exoplanets with well-measured properties orbiting nearby bright stars, ensuring fruitful studies of these systems for many years to come., Comment: 20 pages, 4 figures, 4 tables, 26 sub-Neptunes, 31 TOIs. Accepted to AJ
- Published
- 2024
97. Detection of X-ray Emission from a Bright Long-Period Radio Transient
- Author
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Wang, Ziteng, Rea, Nanda, Bao, Tong, Kaplan, David L., Lenc, Emil, Wadiasingh, Zorawar, Hare, Jeremy, Zic, Andrew, Anumarlapudi, Akash, Bera, Apurba, Beniamini, Paz, Cooper, A. J., Clarke, Tracy E., Deller, Adam T., Dawson, J. R., Glowacki, Marcin, Hurley-Walker, Natasha, McSweeney, S. J., Polisensky, Emil J., Peters, Wendy M., Younes, George, Bannister, Keith W., Caleb, Manisha, Dage, Kristen C., James, Clancy W., Kasliwal, Mansi M., Karambelkar, Viraj, Lower, Marcus E., Mori, Kaya, Ocker, Stella Koch, Pérez-Torres, Miguel, Qiu, Hao, Rose, Kovi, Shannon, Ryan M., Taub, Rhianna, Wang, Fayin, Wang, Yuanming, Zhao, Zhenyin, Bhat, N. D. R., Dobie, Dougal, Driessen, Laura N., Murphy, Tara, Jaini, Akhil, Deng, Xinping, Jahns-Schindler, Joscha N., Lee, Y. W. J., Pritchard, Joshua, Tuthill, John, and Thyagarajan, Nithyanandan
- Subjects
Astrophysics - High Energy Astrophysical Phenomena - Abstract
Recently, a class of long-period radio transients (LPTs) has been discovered, exhibiting emission on timescales thousands of times longer than radio pulsars. Several models had been proposed implicating either a strong magnetic field neutron star, isolated white dwarf pulsar, or a white dwarf binary system with a low-mass companion. While several models for LPTs also predict X-ray emission, no LPTs have been detected in X-rays despite extensive searches. Here we report the discovery of an extremely bright LPT (10-20 Jy in radio), ASKAP J1832-0911, which has coincident radio and X-ray emission, both with a 44.2-minute period. The X-ray and radio luminosities are correlated and vary by several orders of magnitude. These properties are unique amongst known Galactic objects and require a new explanation. We consider a $\gtrsim0.5$ Myr old magnetar with a $\gtrsim 10^{13}$ G crustal field, or an extremely magnetised white dwarf in a binary system with a dwarf companion, to be plausible explanations for ASKAP J1832-0911, although both explanations pose significant challenges to formation and emission theories. The X-ray detection also establishes a new class of hour-scale periodic X-ray transients of luminosity $\sim10^{33}$ erg/s associated with exceptionally bright coherent radio emission., Comment: 52 pages, 17 figures, 3 tables
- Published
- 2024
98. Comparative study of spectral broadening and few-cycle compression of Yb:KGW laser pulses in gas-filled hollow-core fibers
- Author
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Shalaby, Islam, McDonnell, Michael, Murphy, Colin, Chakraborty, Nisnat, Gray, Kody, Wood, James, Biswas, Dipayan, and Sandhu, Arvinder
- Subjects
Physics - Optics - Abstract
While industrial-grade Yb-based amplifiers have become very prevalent, their limited gain bandwidth has created a large demand for robust spectral broadening techniques that allow for few-cycle pulse compression. In this work, we perform a comparative study between several atomic and molecular gases as media for spectral broadening in a hollow-core fiber geometry. Exploiting nonlinearities such as self-phase modulation, self-steepening, and stimulated Raman scattering, we explore the extent of spectral broadening and its dependence on gas pressure, the critical power for self-focusing, and the optimal regime for few-cycle pulse compression. Using a 3-mJ, 200-fs input laser pulses, we achieve ~ 15 fs, few-cycle pulses with >70% overall energy transmission efficiency. The optimal parameters can be scaled for higher or lower input pulse energies with appropriate gas parameters and fiber geometry., Comment: 9 pages, 3 figures
- Published
- 2024
99. The properties of the interstellar medium in dusty, star-forming galaxies at $z \sim 2-4$: The shape of the CO spectral line energy distributions
- Author
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Taylor, Dominic J., Swinbank, A. M., Smail, Ian, Puglisi, Annagrazia, Birkin, Jack E., Dudzeviciute, Ugne, Chen, Chian-Chou, Ikarashi, S., Castillo, Marta Frias, Weiss, Axel, Li, Zefeng, Chapman, Scott C., Jansen, Jasper, Jimenez-Andrade, E. F., Morabito, Leah K., Murphy, Eric J., Rybak, Matus, and van der Werf, P. P.
- Subjects
Astrophysics - Astrophysics of Galaxies ,Astrophysics - Cosmology and Nongalactic Astrophysics - Abstract
The molecular gas in the interstellar medium (ISM) of star-forming galaxy populations exhibits diverse physical properties. We investigate the $^{12}$CO excitation of twelve dusty, luminous star-forming galaxies at $z \sim 2-4$ by combining observations of the $^{12}$CO from $J_{\rm up} = 1$ to $J_{\rm up} = 8$. The spectral line energy distribution (SLED) has a similar shape to NGC 253, M82, and local ULIRGs, with much stronger excitation than the Milky Way inner disc. By combining with resolved dust continuum sizes from high-resolution $870$-$\mu$m ALMA observations and dust mass measurements determined from multi-wavelength SED fitting, we measure the relationship between the $^{12}$CO SLED and probable physical drivers of excitation: star-formation efficiency, the average intensity of the radiation field $\langle U\rangle$, and the star-formation rate surface density. The primary driver of high-$J_{\rm up}$ $^{12}$CO excitation in star-forming galaxies is star-formation rate surface density. We use the ratio of the CO($3-2$) and CO($6-5$) line fluxes to infer the CO excitation in each source and find that the average ratios for our sample are elevated compared to observations of low-redshift, less actively star-forming galaxies and agree well with predictions from numerical models that relate the ISM excitation to the star-formation rate surface density. The significant scatter in the line ratios of a factor $\approx 3$ within our sample likely reflects intrinsic variations in the ISM properties which may be caused by other effects on the excitation of the molecular gas, such as cosmic ray ionization rates and mechanical heating through turbulence dissipation., Comment: Accepted for publication in MNRAS; 17 pages, 7 figures
- Published
- 2024
100. WEAVE First Light Observations: Origin and Dynamics of the Shock Front in Stephan's Quintet
- Author
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Arnaudova, M. I., Das, S., Smith, D. J. B., Hardcastle, M. J., Hatch, N., Trager, S. C., Smith, R. J., Drake, A. B., McGarry, J. C., Shenoy, S., Stott, J. P., Knapen, J. H., Hess, K. M., Duncan, K. J., Gloudemans, A., Best, P. N., García-Benito, R., Kondapally, R., Balcells, M., Couto, G. S., Abrams, D. C., Aguado, D., Aguerri, J. A. L., Barrena, R., Benn, C. R., Bensby, T., Berlanas, S. R., Bettoni, D., Cano-Infantes, D., Carrera, R., Concepción, P. J., Dalton, G. B., D'Ago, G., Dee, K., Domínguez-Palmero, L., Drew, J. E., Escott, E. L., Fariña, C., Fossati, M., Fumagalli, M., Gafton, E., Gribbin, F. J., Hughes, S., Iovino, A., Jin, S., Lewis, I. J., Longhetti, M., Méndez-Abreu, J., Mercurio, A., Molaeinezhad, A., Molinari, E., Monguió, M., Murphy, D. N. A., Picó, S., Pieri, M. M., Ridings, A. W., Romero-Gómez, M., Schallig, E., Shimwell, T. W., Skvarĉ, R., Stuik, R., Vallenari, A., van der Hulst, J. M., Walton, N. A., and Worley, C. C.
- Subjects
Astrophysics - Astrophysics of Galaxies - Abstract
We present a detailed study of the large-scale shock front in Stephan's Quintet, a byproduct of past and ongoing interactions. Using integral-field spectroscopy from the new William Herschel Telescope Enhanced Area Velocity Explorer (WEAVE), recent 144 MHz observations from the LOFAR Two-metre Sky Survey (LoTSS), and archival data from the Very Large Array and James Webb Space Telescope (JWST), we obtain new measurements of key shock properties and determine its impact on the system. Harnessing the WEAVE large integral field unit's (LIFU) field of view (90 $\times$ 78 arcsec$^{2}$), spectral resolution ($R\sim2500$) and continuous wavelength coverage across the optical band, we perform robust emission line modeling and dynamically locate the shock within the multi-phase intergalactic medium (IGM) with higher precision than previously possible. The shocking of the cold gas phase is hypersonic, and comparisons with shock models show that it can readily account for the observed emission line ratios. In contrast, we demonstrate that the shock is relatively weak in the hot plasma visible in X-rays (with Mach number of $\mathcal{M} \sim 2 - 4$), making it inefficient at producing the relativistic particles needed to explain the observed synchrotron emission. Instead, we propose that it has led to an adiabatic compression of the medium, which has increased the radio luminosity ten-fold. Comparison of the Balmer line-derived extinction map with the molecular gas and hot dust observed with JWST suggests that pre-existing dust may have survived the collision, allowing the condensation of H$_{2}$ - a key channel for dissipating the shock energy., Comment: 23 pages, 15 figures, accepted for publication in MNRAS
- Published
- 2024
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