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91 results on '"Pameijer, Frank A."'

51. Decreased 3D observer variation with matched CT-MRI, for target delineation in Nasopharynx cancer

Author

Kaanders Johannes HAM, Eisbruch Avraham, Pameijer Frank A, Nowak Peter JCM, Duppen Joop C, Fitton Isabelle, Steenbakkers Roel JHM, Rasch Coen RN, Paulsen Frank, and van Herk Marcel

Subjects
Medical physics. Medical radiology. Nuclear medicine, R895-920, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract

Abstract Purpose To determine the variation in target delineation of nasopharyngeal carcinoma and the impact of measures to minimize this variation. Materials and methods For ten nasopharyngeal cancer patients, ten observers each delineated the Clinical Target Volume (CTV) and the CTV elective. After 3D analysis of the delineated volumes, a second delineation was performed. This implied improved delineation instructions, a combined delineation on CT and co-registered MRI, forced use of sagittal reconstructions, and an on-line anatomical atlas. Results Both for the CTV and the CTV elective delineations, the 3D SD decreased from Phase 1 to Phase 2, from 4.4 to 3.3 mm for the CTV and from 5.9 to 4.9 mm for the elective. There was an increase agreement, where the observers intended to delineate the same structure, from 36 to 64 surface % (p = 0.003) for the CTV and from 17 to 59% (p = 0.004) for the elective. The largest variations were at the caudal border of the delineations but these were smaller when an observer utilized the sagittal window. Hence, the use of sagittal side windows was enforced in the second phase and resulted in a decreased standard deviation for this area from 7.7 to 3.3 mm (p = 0.001) for the CTV and 7.9 to 5.6 mm (p = 0.03) for the CTV elective. Discussion Attempts to decrease the variation need to be tailored to the specific causes of the variation. Use of delineation instructions multimodality imaging, the use of sagittal windows and an on-line atlas result in a higher agreement on the intended target.

Published
2010
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52. The interobserver agreement in the detection of recurrent HNSCC using MRI including diffusion weighted MRI

Author

Peltenburg, Boris, primary, Driessen, Juliette P., additional, Philippens, Marielle E.P., additional, Pameijer, Frank A., additional, Castelijns, Jonas, additional, Dankbaar, Jan Willem, additional, Dorgelo, Bart, additional, Lange, Charlotte A.H., additional, Meijer, Frederick J.A., additional, Palm, Walter M., additional, Roosendaal, Stefan D., additional, Steens, Stefan C.A., additional, Verbist, Berit M., additional, Stegeman, Inge, additional, Janssen, Luuk M., additional, de Bree, Remco, additional, and Terhaard, Chris H.J., additional

Published
2018
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56. Radiology quiz case 2

Author

Lupprino, Floriana S., Pameijer, Frank A., and Balm, Alfons J. M.

Subjects
Laryngeal cancer -- Diagnosis, Health
Published
2005

58. Validated guidelines for tumor delineation on magnetic resonance imaging for laryngeal and hypopharyngeal cancer

Author

Jager, Elise Anne, Ligtenberg, Hans, Caldas-Magalhaes, Joana, Schakel, Tim, Philippens, Marielle E., Pameijer, Frank A., Kasperts, Nicolien, Willems, Stefan M., Terhaard, Christiaan H., and Raaijmakers, Cornelis P.

Abstract

Background: Validation of magnetic resonance imaging (MRI) and development of guidelines for the delineation of the gross tumor volume (GTV) is of utmost importance to benefit from the visibility of anatomical details on MR images and to achieve an accurate GTV delineation. In the ideal situation, the GTV delineation corresponds to the histopathologically determined ‘true tumor volume’. Consequently, we developed guidelines for GTV delineation of laryngeal and hypopharyngeal tumors on MRI and determined the accuracy of the resulting delineation of the tumor outline on histopathology as gold standard. Material and methods: Twenty-seven patients with T3 or T4 laryngeal/hypopharyngeal cancer underwent a MRI scan before laryngectomy. Hematoxylin and eosin sections were obtained from surgical specimens and tumor was delineated by one pathologist. GTV was delineated on MR images by three independent observers in two sessions. The first session (del1) was performed according to clinical practice. In the second session (del2) guidelines were used. The reconstructed specimen was registered to the MR images for comparison of the delineated GTVs to the tumor on histopathology. Volumes and overlap parameters were analyzed. A target margin needed to assure tumor coverage was determined. Results: The median GTVs (del1: 19.4 cm3, del2: 15.8 cm3) were larger than the tumor volume on pathology (10.5 cm3). Comparable target margins were needed for both delineation sessions to assure tumor coverage. By adding these margins to the GTVs, the target volumes for del1 (median: 81.3 cm3) were significantly larger than for del2 (median: 64.2 cm3) (p ≤ 0.0001) with similar tumor coverage. Conclusions: In clinical radiotherapy practice, the delineated GTV on MRI is twice as large as the tumor volume. Validated delineation guidelines lead to a significant decrease in the overestimation of the tumor volume.

Published
2016
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64. Correlation of human papillomavirus status with apparent diffusion coefficient of diffusion-weighted MRI in head and neck squamous cell carcinomas

Author

Driessen, Juliette P., primary, van Bemmel, Alexander J. M., additional, van Kempen, Pauline M. W., additional, Janssen, Luuk M., additional, Terhaard, Chris H. J., additional, Pameijer, Frank A., additional, Willems, Stefan M., additional, Stegeman, Inge, additional, Grolman, Wilko, additional, and Philippens, Marielle E.P., additional

Published
2015
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65. Prostate tumor delineation using multiparametric magnetic resonance imaging: Inter-observer variability and pathology validation

Author

Steenbergen, Peter, primary, Haustermans, Karin, additional, Lerut, Evelyne, additional, Oyen, Raymond, additional, De Wever, Liesbeth, additional, Van den Bergh, Laura, additional, Kerkmeijer, Linda G.W., additional, Pameijer, Frank A., additional, Veldhuis, Wouter B., additional, van der Voort van Zyp, Jochem R.N., additional, Pos, Floris J., additional, Heijmink, Stijn W., additional, Kalisvaart, Robin, additional, Teertstra, Hendrik J., additional, Dinh, Cuong V., additional, Ghobadi, Ghazaleh, additional, and van der Heide, Uulke A., additional

Published
2015
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67. The accuracy of target delineation in laryngeal and hypopharyngeal cancer

Author

Caldas-Magalhaes, Joana, primary, Kooij, Nina, additional, Ligtenberg, Hans, additional, Jager, Elise A., additional, Schakel, Tim, additional, Kasperts, Nicolien, additional, Pameijer, Frank A., additional, Terhaard, Chris H. J., additional, Janssen, Luuk M., additional, van Diest, Paul J., additional, Philippens, Marielle E. P., additional, and Raaijmakers, Cornelis P. J., additional

Published
2015
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74. Diagnostic and Treatment-Related Challenges in Sinonasal Teratocarcinosarcoma: A Report of Three Cases

Author

F. Julius Scheurleer, W., W. Braunius, Weibel, M. Tijink, Bernard, M. Janssen, Luuk, A. Pameijer, Frank, E. Breimer, Gerben, J. Smid, Ernst, de Bree, Remco, A. Devriese, Lot, and A. Rijken, Johannes

Abstract

Background. Sinonasal teratocarcinosarcoma is a rare, aggressive malignancy located almost exclusively in the nasal cavity, paranasal sinuses, or anterior skull base. Histopathological diagnosis can be challenging due to the heterogeneous composition. Methods. Retrospective analysis of 3 patients with sinonasal teratocarcinosarcoma diagnosed and treated at the University Medical Center Utrecht was conducted. Results. Patients presented with nasal obstruction, epistaxis, headaches, or behavioral changes. All three patients had locally advanced disease, and one had lymph node metastases. Two patients underwent surgery followed by radiotherapy, and one underwent neoadjuvant chemotherapy followed by surgery. The follow-up duration ranged from 3 to 32 months. All three patients died due to progression of their disease. Conclusion. Sinonasal teratocarcinosarcoma is characterized by rapid, aggressive local expansion. The prognosis is poor due to a high risk of metastases and locally recurrent disease. Multimodality treatment consisting of surgery, followed by (chemo)‐radiotherapy, is essential for optimizing outcomes. Neoadjuvant therapy offers a promising treatment option.

Published
2023
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86. In Vivo Imaging of the Inner Ear at 7T MRI

Author

Egmond, Sylvia L. van, Visser, Fredy, Pameijer, Frank A., and Grolman, Wilko

Abstract

The implementation of 7T magnetic resonance imaging for human use has the potential to further advance spatial resolution beyond that of 3T. This could result in potential advantages in the depiction of the membranous structures of the inner ear. The inner ear is particularly challenging to visualize at 7T because of its anatomic location, which can lead to susceptibility banding artifacts and signal loss.

Published
2015
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87. Clinical Problem Solving: Radiology.

Author

Saint John, Maie A.R., Maghami, Ellie G., Bhuta, Sunita, Lufkin, Robert B., Abemayor, Elliot, Geurts, Tom W., Lohuis, Peter J.F.M., Pameijer, Frank A., van den Brekel, Michiel W.M., Bryan, R. Nick, and Zinreich, S. James

Subjects
RADIOLOGY, SMOOTH muscle tumors, NASOPHARYNX diseases, LARYNGEAL diseases
Abstract

Presents a quiz on clinical problem solving using radiology. Diagnosis of vascular leiomyoma of the larynx; Therapy for nasopharyngeal lipoma.

Published
2002
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88. Ex Vivo and In Vivo Imaging of the Inner Ear at 7 Tesla MRI

Author

Egmond, Sylvia L. van, Visser, Fredy, Pameijer, Frank A., and Grolman, Wilko

Abstract

The implementation of 7.0 Tesla magnetic resonance imaging (MRI) for human use has the potential to further advance spatial resolution beyond that of 1.5T and 3T. This could result in potential advantages in the depiction of the membranous structures of the inner ear.

Published
2014
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89. Iodine-131 Therapy in Sporadic Nontoxic Goiter.

Author

de Klerk, John M. H., van Isselt, Johannes W., van Dijk, Aalt, Hakman, Marc E., Pameijer, Frank A., Koppeschaar, Hans P. F., Zelissen, Pierre M. J., van Schaik, Jan P. J., and van Rijk, Peter P.

Published
1997

90. [Atypical pain and a unilateral swelling of the neck: a patient with TIPIC-syndrome].

Author

de Jong MA, Pameijer FA, van der Veen EL, de Ru JA, and Stokroos RJ

Subjects
Humans, Inflammation, Middle Aged, Neck, Syndrome, Chest Pain, Edema diagnosis, Edema etiology
Abstract

Background: TIPIC-syndrome (Transient Perivascular Inflammation of the Carotid Artery) as a cause of a painful lump in the neck is not often described in the literature. This self-limiting perivascular inflammation of the carotid bifurcation is relatively unknown., Case: We describe a 50-year old patient, in whom a CT-scan that was performed because of unilateral pain in the neck and paranasal sinuses revealed the unexpected diagnosis of TIPIC-syndrome., Conclusion: Knowledge of the symptoms at presentation and the following clinical course of TIPIC-syndrome can prevent unnecessary use of additional tests.

Published
2022

91. Diffusion-weighted MR imaging in laryngeal and hypopharyngeal carcinoma: association between apparent diffusion coefficient and histologic findings.

Author

Driessen JP, Caldas-Magalhaes J, Janssen LM, Pameijer FA, Kooij N, Terhaard CH, Grolman W, and Philippens ME

Subjects
Aged, Carcinoma, Squamous Cell surgery, Female, Humans, Hypopharyngeal Neoplasms surgery, Laryngeal Neoplasms surgery, Laryngectomy, Male, Middle Aged, Neoplasm Staging, Pharyngectomy, Retrospective Studies, Carcinoma, Squamous Cell pathology, Diffusion Magnetic Resonance Imaging methods, Hypopharyngeal Neoplasms pathology, Laryngeal Neoplasms pathology
Abstract

Purpose: To investigate the relationship between the histologic characteristics of head and neck squamous cell carcinoma and apparent diffusion coefficient (ADC) at diffusion-weighted magnetic resonance (MR) imaging., Materials and Methods: The institutional ethics committee approved this study and waived informed consent. In head and neck squamous cell carcinoma, local failure after chemotherapy and/or radiation therapy correlates with pretreatment ADC. However, the histopathologic basis of this correlation remains unclear. In this study, 16 patients with head and neck squamous cell carcinoma were enrolled (median age, 60 years; range, 49-78 years). Before undergoing total laryngectomy, patients underwent 1.5-T diffusion-weighted MR imaging. After resection, whole-mount hematoxylin-eosin-stained sections were registered to the MR images. Cellular density; nuclear, cytoplasmic, and stromal area; and nuclear-cytoplasmic ratio within the tumor were calculated by using image-based segmentation on four consecutive slices. Mean ADC of the corresponding tumor region was calculated. Spearman correlations between ADC and histologic characteristics were calculated., Results: ADC was significantly and inversely correlated with cell density (n = 16, r = -0.57, P = .02), nuclear area (n = 12, r = -0.64, P = .03), and nuclear-cytoplasmic ratio (n = 12, r = -0.77, P ≤ .01). ADC was significantly and positively correlated with percentage area of stroma (n = 12, r = 0.69, P = .01). Additionally, the percentage area of stroma was strongly interdependent with the percentage area of nuclei (n = 12, r = -0.97, P ≤ .01)., Conclusion: ADC was significantly correlated with cellularity, stromal component, and nuclear-cytoplasmic ratio. The positive correlation of ADC and stromal component suggests that the poor prognostic value of high pretreatment ADC might partly be attributed to the tumor-stroma component, a known predictor of local failure.

Published
2014
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