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51. Regulatory T Cells as an Escape Mechanism to the Immune Response in Taenia crassiceps Infection

Author

Adalid-Peralta, Laura, primary, Lopez-Roblero, Alexander, additional, Camacho-Vázquez, Cynthia, additional, Nájera-Ocampo, Marisol, additional, Guevara-Salinas, Adrián, additional, Ruiz-Monroy, Nataly, additional, Melo-Salas, Marlene, additional, Morales-Ruiz, Valeria, additional, López-Recinos, Dina, additional, Ortiz-Hernández, Edgar, additional, Demengeot, Jocelyne, additional, Vazquez-Perez, Joel A., additional, Arce-Sillas, Asiel, additional, Gomez-Fuentes, Sandra, additional, Parkhouse, Robert Michael Evans, additional, Fragoso, Gladis, additional, Sciutto, Edda, additional, and Sevilla-Reyes, Edgar E., additional

Published
2021
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59. Amino acid changes in HA and determinants of pathogenicity associated with influenza virus A H1N1pdm09 during the winter seasons 2015-2016 and 2016-2017 in Mexico

Author

Vázquez-Pérez, Joel Armando, De La Rosa-Zamboni, Daniela, Vega-Sánchez, Ángel Emmanuel, Gutiérrez-González, Luis Horacio, Téllez-Navarrete, Norma Angélica, Campos, Fernando, Guadarrama-Pérez, Cristóbal, Sandoval, José Luis, Castillejos-López, Manuel, Jiménez-Juárez, Rodolfo Norberto, Sánchez-Huerta, José Luis, Pérez-Méndez, Brenda Berenice, and Pérez-Padilla, Rogelio

Published
2019
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60. Genomic Analysis of Early SARS-CoV-2 Variants Introduced in Mexico

Author

Taboada, Blanca, primary, Vazquez-Perez, Joel Armando, additional, Muñoz-Medina, José Esteban, additional, Ramos-Cervantes, Pilar, additional, Escalera-Zamudio, Marina, additional, Boukadida, Celia, additional, Sanchez-Flores, Alejandro, additional, Isa, Pavel, additional, Mendieta-Condado, Edgar, additional, Martínez-Orozco, José A., additional, Becerril-Vargas, Eduardo, additional, Salas-Hernández, Jorge, additional, Grande, Ricardo, additional, González-Torres, Carolina, additional, Gaytán-Cervantes, Francisco Javier, additional, Vazquez, Gloria, additional, Pulido, Francisco, additional, Araiza-Rodríguez, Adnan, additional, Garcés-Ayala, Fabiola, additional, González-Bonilla, Cesar Raúl, additional, Grajales-Muñiz, Concepción, additional, Borja-Aburto, Víctor Hugo, additional, Barrera-Badillo, Gisela, additional, López, Susana, additional, Hernández-Rivas, Lucía, additional, Perez-Padilla, Rogelio, additional, López-Martínez, Irma, additional, Ávila-Ríos, Santiago, additional, Ruiz-Palacios, Guillermo, additional, Ramírez-González, José Ernesto, additional, and Arias, Carlos F., additional

Published
2020
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61. Genomic analysis of early SARS-CoV-2 strains introduced in Mexico

Author

Taboada, Blanca, primary, Vazquez-Perez, Joel Armando, additional, Muñoz Medina, José Esteban, additional, Cervantes, Pilar Ramos, additional, Escalera-Zamudio, Marina, additional, Boukadida, Celia, additional, Sanchez-Flores, Alejandro, additional, Isa, Pavel, additional, Condado, Edgar Mendieta, additional, Martínez-Orozco, José Arturo, additional, Becerril-Vargas, Eduardo, additional, Salas-Hernández, Jorge, additional, Grande, Ricardo, additional, González-Torres, Carolina, additional, Gaytán-Cervantes, Francisco Javier, additional, Vazquez, Gloria, additional, Pulido, Francisco, additional, Rodríguez, Adnan Araiza, additional, Garcés Ayala, Fabiola, additional, González Bonilla, Cesar Raúl, additional, Muñiz, Concepción Grajales, additional, Borja Aburto, Víctor Hugo, additional, Badillo, Gisela Barrera, additional, López, Susana, additional, Rivas, Lucía Hernández, additional, Perez-Padilla, Rogelio, additional, Martínez, Irma López, additional, Ávila-Ríos, Santiago, additional, Ruiz-Palacios, Guillermo, additional, Ramírez-González, José Ernesto, additional, and Arias, Carlos F., additional

Published
2020
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64. Trajectory Tracking Using Adaptive Fractional PID Control of Biped Robots with Time-Delay Feedback

Author

Perez, Joel, Perez, Jose P., Mendez-Barrios, C.F., and Ramírez-Rivera, V.

Subjects
Technology & Engineering / Robotics
Abstract

This paper presents the application of fractional order time-delay adaptive neural networks to the trajectory tracking for chaos synchronization between Fractional Order delayed plant, reference and fractional order time-delay adaptive neural networks. For this purpose, we obtained two control laws and laws of adaptive weights online, obtained using the fractional order Lyapunov-Krasovskii stability analysis methodology. The main methodologies, on which the approach is based, are fractional order PID the fractional order Lyapunov-Krasovskii functions methodology, although the results we obtain are applied to a wide class of non-linear systems, we will apply it in this chapter to a bipedal robot. The structure of the biped robot is designed with two degrees of freedom per leg, corresponding to the knee and hip joints. Since torso and ankle are not considered, it is obtained a 4-DOF system, and each leg, we try to force this biped robot to track a reference signal given by undamped Duffing equation. To verify the analytical results, an example of dynamical network is simulated, and two theorems are proposed to ensure the tracking of the nonlinear system. The tracking error is globally asymptotically stabilized by two control laws derived based on a Lyapunov-Krasovskii functional.

Published
2019

65. A (H1N1) pdm09 HA D222 variants associated with severity and mortality in patients during a second wave in Mexico

Author

Vazquez-Perez Joel A, Isa Pavel, Kobasa Darwyn, Ormsby Christopher E, Ramírez-Gonzalez Jose E, Romero-Rodríguez Damaris P, Ranadheera Charlene, Li Yan, Bastien Nathalie, Embury-Hyatt Carissa, González-Duran Elizabeth, Barrera-Badillo Gisela, Ablanedo-Terrazas Yuria, Sevilla-Reyes Edgar E, Escalera-Zamudio Marina, Cobián-Güemes Ana G, Lopez Irma, Ortiz-Alcántara Joanna, Alpuche-Aranda Celia, Perez-Padilla Jose R, and Reyes-Terán Gustavo

Subjects
Infectious and parasitic diseases, RC109-216
Abstract

Abstract Background Pandemic type A (H1N1) influenza arose in early 2009, probably in Mexico and the United States, and reappeared in North America in September for seven more months. An amino acid substitution in the hemagglutinin (HA), D222G, has been reported in a significant proportion of patients with a severe and fatal outcome. We studied the prevalence of HA222 substitutions in patients in Mexico during the second wave and its association with clinical outcome and pathogenicity in a mouse model. Methods The nucleotide sequences of hemagglutinin (HA) from viruses collected from 77 patients were determined including 50 severe and fatal cases and 27 ambulatory cases. Deep sequencing was done on 5 samples from severe or fatal cases in order to determine the quasispecies proportion. Weight loss and mortality due to infection with cultured influenza viruses were analyzed in a mouse model. Results Viruses from 14 out of 50 hospitalized patients (28%) had a non aspartic acid residue at the HA 222 position (nD222), while all 27 ambulatory patients had D222 (p = 0.0014). G222 was detected as sole species or in coexistence with N222 and D222 in 12 patients with severe disease including 8 who died. N222 in coexistence with D222 was detected in 1 patient who died and co-occurrence of A222 and V222, together with D222, was detected in another patient who died. The patients with a nD222 residue had higher mortality (71.4%), compared to the group with only D222 (22.2%, p = 0.0008). Four of the 14 viruses from hospitalized patients were cultured and intranasally infected into mice. Two viruses with G222 were lethal while a third virus, with G222, caused only mild illness in mice similar to the fourth virus that contained D222. Conclusions We confirm the elevated incidence of HA222 (H1N1)pdm09 variants in severe disease and mortality. Both clinical and mouse infection data support the idea that nD222 mutations contribute to increased severity of disease but additional determinants in disease outcome may be present.

Published
2013
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75. Retrospective study of the relationship of Torque teno sus virus 1a and Torque teno sus virus 1b with porcine circovirus associated disease

Author

Vargas-Ruiz, Alejandro, Ramírez-Álvarez, Hugo, Sánchez-Betancourt, José I., Quintero-Ramírez, Víctor, Rangel-Rodríguez, Ignacio C., Vázquez-Perez, Joel A., and García-Camacho, Lucia A.

Subjects
Circovirus, Swine Diseases, Torque teno virus, Swine, animal diseases, Animals, Mexico, Article, DNA Virus Infections, Phylogeny
Abstract

Genus Iotatorquevirus consists of 2 species, Torque teno sus virus 1a and Torque teno sus virus 1b, which are ubiquitous in swine populations, and are widely reported in association with porcine circovirus associated disease (PCVAD). To evaluate the relationship with PCVAD, 100 formalin-fixed paraffin-embedded tissue samples were used to detect both Iotatorquevirus species by nested PCR and sequencing. Sixty-eight PCVAD cases were selected as well as 32 porcine circovirus type 2 (PCV2) non-affected cases. Overall, 33 of the 100 cases were positive for Torque teno sus virus 1a and 8 of 100 were positive for Torque teno sus virus 1b. Only 24 of 68 (35%) PCVAD cases were positive for Torque teno sus virus 1a; 39% (9/23) of post-weaning multisystemic wasting syndrome, and 33% (15/45) of PCV2-associated reproductive failure cases. Among PCV2 non-affected cases, 28% were positive for Torque teno sus virus 1a and 6% were positive for Torque teno sus virus 1b. Torque teno sus virus 1b was not detected in PCV2-associated reproductive failure cases. Regardless of the PCV2-status, a lower frequency of both Iotatorquevirus species was found than depicted in other reports and there was no statistical relationship with PCVAD (χ2 < 0.01). Given the worldwide genomic variability of Iotatorquevirus species, it is feasible that species prevalent in Mexico share a lower nucleotide sequence identity, leading to different pathogenic potential.

Published
2017

76. Virome and bacteriome characterization of children with pneumonia and asthma in Mexico City during winter seasons 2014 and 2015

Author

Romero-Espinoza, Jose A., primary, Moreno-Valencia, Yazmin, additional, Coronel-Tellez, Rodrigo H., additional, Castillejos-Lopez, Manuel, additional, Hernandez, Andres, additional, Dominguez, Aaron, additional, Miliar-Garcia, Angel, additional, Barbachano-Guerrero, Arturo, additional, Perez-Padilla, Rogelio, additional, Alejandre-Garcia, Alejandro, additional, and Vazquez-Perez, Joel A., additional

Published
2018
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79. Remedios de mi tierra: An Oral History Project on the Changes and Continuity of the Traditional Healing Knowledge and Practices of a Mexican Immigrant Mother from Guanajuato, Mexico

Author

Saldana Perez, Joel Angel and Saldana Perez, Joel Angel

Abstract

This thesis looks at the impact of migration and place on the traditional healing knowledge and practices of a Mexican immigrant mother from Guanajuato, Mexico: Sofia Perez. Through the use of oral history methodology and the application of the Traditional Ecological Knowledge and Wisdom (TEKW) model and the Social Ecological Model (SEM) to analyze the narratives, this study looks at the origin of Sofia's healing knowledge and practices and at how she has managed to keep these traditions alive despite migrating to the United States and living in a society that may not believe in the efficacy of these healing traditions. The application of the Traditional Ecological Knowledge and Wisdom (TEKW) model provided insight into the healing traditions of Sofia's home community and the ways in which these were learned, practiced, and preserved and proved useful in looking at how this was done by Sofia before and after migrating. Next, the Social Ecological Model (SEM) proved useful in looking at how place and its various social, cultural, and ecological aspects have influenced Sofia's use of traditional medicine since she migrated. Overall, Sofia's knowledge and practices have been impacted by migration and place; however, she continues to practice these traditions as best as she can.

Published
2017

83. Performance analysis of the MEDA's Thermal InfraRed Sensor (TIRS) on board the Mars 2020

Author

Sebastian, Eduardo, primary, Perez, Joel, additional, Bravo, Andres, additional, Ferrandiz, Ricardo, additional, Fernandez, Maite, additional, Manfredi, J.A. Rodriguez, additional, Martinez, German, additional, Pena, Antonio, additional, Gonzalez, David, additional, Moreno, Jose, additional, de Lucas, Javier, additional, Hernandez, Pedro, additional, Perez-Grande, Isabel, additional, Chamorro, Adrian, additional, and Ramos, Miguel, additional

Published
2017
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87. Split-family SUSY, <math><mrow><mi>U</mi><msup><mrow><mo>(</mo><mn>2</mn><mo>)</mo></mrow><mn>5</mn></msup></mrow></math> flavour symmetry and neutrino physics

Author

Jones-Perez, Joel

Subjects
High Energy Physics - Phenomenology, High Energy Physics - Phenomenology (hep-ph), High Energy Physics::Phenomenology, FOS: Physical sciences, High Energy Physics::Experiment, Particle Physics - Phenomenology
Abstract

In split-family SUSY, one can use a U(2)^3 symmetry to protect flavour observables in the quark sector from SUSY contributions. However, attempts to extend this procedure to the lepton sector by using an analogous U(2)^5 symmetry fail to reproduce the neutrino data without introducing some form of fine-tuning. In this work, we solve this problem by shifting the U(2)^2 symmetry acting on leptons towards the second and third generations. This allows neutrino data to be reproduced without much difficulties, as well as protecting the leptonic flavour observables from SUSY. Key signatures are a $\mu\to e\gamma$ branching ratio possibly observable in the near future, as well as having selectrons as the lightest sleptons., Comment: 9 pages, 3 figures; v2: improved discussion of LFV processes, results unchanged; v3: Minor changes, version accepted for publication in EPJ C

Published
2014

88. EV‐D68 infection in children with asthma exacerbation and pneumonia in Mexico City during 2014 autumn

Author

Vazquez‐Perez, Joel A., primary, Ramirez‐Gonzalez, Jose E., additional, Moreno‐Valencia, Yazmin, additional, Hernandez‐Hernandez, Victor A., additional, Romero‐Espinoza, Jose A. I., additional, Castillejos‐Lopez, Manuel, additional, Hernandez, Andres, additional, Perez‐Padilla, Rogelio, additional, Oropeza‐Lopez, Lizbeth E., additional, Escobar‐Escamilla, Noe, additional, Gonzalez‐Villa, Maribel, additional, Alejandre‐Garcia, Alejandro, additional, Regalado‐Pineda, Justino, additional, Santillan‐Doherty, Patricio, additional, Lopez‐Martínez, Irma, additional, Diaz‐Quiñonez, Alberto, additional, and Salas‐Hernandez, Jorge, additional

Published
2016
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89. A High-Resolution Modeling Strategy to Assess Impacts of Climate Change for Mesoamerica and the Caribbean

Author

Oglesby, Robert, primary, Rowe, Clinton, additional, Grunwaldt, Alfred, additional, Ferreira, Ines, additional, Ruiz, Franklyn, additional, Campbell, Jayaka, additional, Alvarado, Luis, additional, Argenal, Francisco, additional, Olmedo, Berta, additional, del Castillo, Alejandro, additional, Lopez, Pilar, additional, Matos, Edwards, additional, Nava, Yosef, additional, Perez, Carlos, additional, and Perez, Joel, additional

Published
2016
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90. Inflammation plays a critical role in 2,8-dihydroxyadenine nephropathy

Author

Bouderlique, Elise, Tang, Ellie, Perez, Joëlle, Ea, Hang-Korng, Renaudin, Felix, Coudert, Amélie, Vandermeersch, Sophie, Bazin, Dominique, Haymann, Jean-Philippe, Saint-Jacques, Camille, Frochot, Vincent, Daudon, Michel, and Letavernier, Emmanuel

Subjects
2,8-Dihydroxyadenine, Adenine phosphoribosyl transferase (APRT), Kidney, Inflammation, Interleukin-1 beta, Biochemistry, QD415-436, Physical and theoretical chemistry, QD450-801, Mathematics, QA1-939
Abstract

Adenine phosphoribosyltransferase (APRT) deficiency is a genetic disease characterized by an increased production of 2,8 dihydroxyadenine (2,8-DHA) precipitating in urine, leading to a crystalline nephropathy and end-stage renal disease. Here, we describe the high prevalence of granuloma (88%) in biopsies from patients with APRT deficiency. A murine model of 2,8-DHA nephropathy was generated, showing that anakinra or dexamethasone, combined with allopurinol, improved renal function to a larger extent than allopurinol alone, the standard therapy. Inflammation plays a critical role in the development of 2,8-DHA nephropathy, and therapy based upon drugs targeting innate immunity could improve renal function recovery.

Published
2021
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91. Water disinfection using a batch solar reactor

Author

Solís, José, Perez, Joel, Estrada, Walter, Zanabria, Pedro, López, Alcides, Palomino, Javier, Díaz, José, Rodríguez, Juan, and Carpio, Edward

Subjects
Radiación ultravioleta, Agua, Purificación, Energía solar
Abstract

En este trabajo se muestran los estudios de desinfección y descontaminación solar de agua contenida en envases de plástico diseñados específicamente como un reactor que utiliza el efecto combinado de la banda ultravioleta-A (310 - 400 nm) y la descontaminación basada en la tecnología avanzada de oxidación denominada fotocatálisis heterogénea con óxido de titanio. Los resultados obtenidos en los análisis de propiedades de descontaminación y desinfección solar de agua en este nuevo tipo de reactor han mostrado resultados promisorios para el tratamiento de agua en zonas rurales, lográndose tratar hasta 200 L en un día de tratamiento. Water disinfection was reached by using solar radiation. It uses the effect of the UV-A component of the solar radiation (310 - 400 nm) impinging onto a specific designed reactor and driving two effects for bacteria inactivation, the so called photolysis and photocatalysis. Designed system works under bath conditions, it was optimized under laboratory conditions and tested on site. Preliminary results indicate us that is possible treat volumes of the order of 200 L in just one day.

Published
2006

92. The Cope Rearrangement of 1,5-Dimethylsemibullvalene-2(4)-d1: Experimental Evidence for Heavy-Atom Tunneling.

Author

Schleif, Tim, Mieres ‐ Perez, Joel, Henkel, Stefan, Ertelt, Melanie, Borden, Weston Thatcher, and Sander, Wolfram

Subjects
*ISOMERISM, *THERMODYNAMICS, *CRYOGENICS, *CHEMICAL reactions, *REARRANGEMENTS (Chemistry)
Abstract

As an experimental test of the theoretical prediction that heavy-atom tunneling is involved in the degenerate Cope rearrangement of semibullvalenes at cryogenic temperatures, monodeuterated 1,5-dimethylsemibullvalene isotopomers were prepared and investigated by IR spectroscopy using the matrix isolation technique. As predicted, the less thermodynamically stable isotopomer rearranges at cryogenic temperatures in the dark to the more stable one, while broadband IR irradiation above 2000 cm−1 results in an equilibration of the isotopomeric ratio. Since this reaction proceeds with a rate constant in the order of 10−4 s−1 despite an experimental barrier of Ea=4.8 kcal mol−1 and with only a shallow temperature dependence, the results are interpreted in terms of heavy-atom tunneling. [ABSTRACT FROM AUTHOR]

Published
2017
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98. SUSY Flavour at LHC7

Author

JONES-PEREZ, Joel, primary, Calibbi, Lorenzo, additional, Hodgkinson, R. N., additional, Masiero, Antonio, additional, and Vives, Oscar M., additional

Published
2012
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