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O presente artigo analisa as hipóteses de provisão de garantias ao parceiro-privado, contratos de parcerias público-privadas, por meio de empresas estatais e de fundos garantidores. O trabalho avalia a natureza jurídica e o regime jurídico dos fundos garantidores e das empresas estatais garantidoras de parcerias público-privadas, bem como analisa as características e o grau de segurança das garantidas prestadas por tais figuras.

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El efecto insulinotrópico de la hormona incretina GLP-1 (péptido relacionado con el glucagón de tipo 1) así como su capacidad de mantener la homeostasis de la glucosa ha suscitado gran interés como agente terapéutico en el tratamiento de la diabetes tipo 2. En la última década, las investigaciones se han enfocado en el desarrollo de análogos de GLP-1 con una mayor estabilidad en la circulación que el péptido endógeno como son la Exendina-4 y el Liraglutide. Además, tanto GLP-1 como sus análogos ejercen otros efectos extra-pancreáticos e independientes del control de la glucemia como en el sistema cardiovascular y en la fisiología pulmonar, entre otros. El propósito de este trabajo fue estudiar los efectos de los análogos de GLP-1 en la función pulmonar durante la etapa fetal, neonatal y adulta. Haciendo hincapié en la síntesis de los componente del surfactante pulmonar como sistema clave de la estabilidad alveolar. Sus acciones como agentes moduladores de la función pulmonar durante la organogénesis sugieren aplicaciones terapéuticas potenciales de estos péptidos en patologías respiratorias asociadas a inmadurez pulmonar tras el nacimiento. Asimismo, los efectos de Liraglutide descritos en el sistema cardiopulmonar independientes del control de la glucemia en un modelo de diabetes en etapa adulta pueden resultar de gran utilidad para mitigar las deficiencias en la circulación pulmonar asociada a la diabetes. Por tanto nuestras investigaciones aportan nuevos conocimientos sobre los efectos de los análogos de GLP-1 independientes de la homeostasis de la glucosa, los cuales podría tener ciertas aplicaciones terapéuticas.

INTRODUÇÃO: Este artigo relata uma intervenção grupal com ênfase na revisão de vida, que buscou promover evocação de lembranças e reflexão sobre atividades de interesse e projeto de vida de idosos. OBJETIVOS: Descrever e analisar a intervenção grupal realizada. PROCEDIMENTOS METODOLÓGICOS: Pesquisa-intervenção realizada com sete idosos, usuários de um Centro de Convivência na Capital Paulista, no ano de 2006. A pesquisa compreendeu intervenção em nove encontros e análise de comportamentos e opiniões. Os dados foram obtidos através de observação e entrevistas e, analisados em seu conteúdo. RESULTADOS: Os idosos refletiram sobre a possibilidade de terem projetos de vida e demonstraram que o espaço grupal foi propício para ampliação do contato social e identificações mútuas. A intervenção favoreceu a ampliação da rede relacional dos idosos e ressignificação de suas trajetórias de vida e do próprio envelhecimento. CONCLUSÃO: Acredita-se que o trabalho com a revisão de vida configura-se como um potencial e importante recurso a ser utilizado pelo terapeuta ocupacional no atendimento à população idosa. INTRODUCTION: This article reports on a group intervention focused on life review, so that elderly could both evoke their memories and reflect on their activities of interest and life projects. OBJECTIVES: Describe and analyse the performed group intervention. METHODOLOGICAL PROCEDURES: An intervention-research carried out with seven elderly, users of a daycare center in São Paulo, Brazil, in 2006. It included nine encounters and the analysis of behaviors and opinions of elderly about the process that was held. Data were obtained through interviews and observation and analysed in their content. RESULTS: Elderly pondered over the possibility of having life project and presented that the group propitiated an expansion of social contact and their mutual identification. The intervention corroborated to increase aged relational network and to resignify the ederlies life trajectories and their own aging. CONCLUSION: Working with the life review process can be considered as an important resource to be used by occupational therapists in the care of the elderly population.

INTRODUCTION: The main caregiver is the one in charge of tasks, among others, of helping the dependent elderly person with his daily activities and is, in general, a member of his family nucleus. The role of the caregiver falls into his hands, without him being prepared for that. OBJECTIVE: Verify the caregivers preparation regarding the basic care of the elderly inpatients prone to hospital discharge. METHODS: The study was carried out at the Geriatric Ward of Hospital do Servidor Público Estadual Francisco Morato de Oliveira in September and October 2007. It is a descriptive transversal study, with quantitative approach. Identification questionnaires were applied to the caregivers and elderly patients and a semi-structured questionnaire to the caregivers. RESULTS: The study sample was composed of 17 caregivers, being 94% female and 76% daughters. In relation to the preparation to carry out the elderly persons' Daily Living Basic Activities, 65% of the caregivers stated that they feel prepared. It was observed that 59% of the caregivers didn't have doubts before the admission and all the research's participants mentioned they didn't need to receive further orientations. CONCLUSION: It was observed that, in agreement with previous studies, the majority of the caregiver was female and daughters, who did not report doubts with regard to the basic cares before the admission and also affirmed they were prepared for providing care of hospital discharge. This can be a pointer of positive impact of the work of orientation exerted by the interdisciplinary team throughout hospitalization, being objectified one better care of the elderly person in the domicile.

The gut microbiota coexists in partnership with the human host through adaptations to environmental and physiological changes that help maintain dynamic homeostatic healthy states. Break-down of this delicate balance under sustained exposure to stressors (e.g. unhealthy diets) can, however, contribute to the onset of disease. Diet is a key modifiable environmental factor that modulates the gut microbiota and its metabolic capacities that, in turn, could impact human physiology. On this basis, the diet and the gut microbiota could act as synergistic forces that provide resilience against disease or that speed the progress from health to disease states. Associations between unhealthy dietary patterns, non-communicable diseases and intestinal dysbiosis can be explained by this hypothesis. Translational studies showing that dietary-induced alterations in microbial communities recapitulate some of the pathological features of the original host further support this notion. In this introductory paper by the European project MyNewGut, we briefly summarize the investigations conducted to better understand the role of dietary patterns and food components in metabolic and mental health and the specificities of the microbiome-mediating mechanisms. We also discuss how advances in the understanding of the microbiome's role in dietary health effects can help to provide acceptable scientific grounds on which to base dietary advice for promoting healthy living., The MyNewGut project is financially supported by a grant within the EU 7th Framework Programme under Grant Agreement 613979. The EU is not liable for the content presented in this publication. MO is a beneficiary of a >MOVE-IN Louvain> (incoming Post-Doctoral Fellowship co-funded by the Marie Curie Actions of the European).