51. Paediatric new-onset seizure clinic in Australia: Experience and lessons learnt
- Author
-
Snehal, Shah, Lakshmi, Nagarajan, Linda, Palumbo, Peter, Walsh, Jonathan, Silberstein, Patricia, Cannell, and Soumya, Ghosh
- Subjects
Male ,Databases, Factual ,Incidence ,Australia ,Electroencephalography ,Neuroimaging ,Hospitals, Pediatric ,Risk Assessment ,Severity of Illness Index ,Cohort Studies ,Tertiary Care Centers ,Age Distribution ,Seizures ,Child, Preschool ,Humans ,Female ,Age of Onset ,Sex Distribution ,Child ,Retrospective Studies - Abstract
A new-onset seizure clinic (NOSC) was established at our hospital in 2011, with the aim to provide accurate diagnosis and appropriate management to children with new-onset seizures or seizure mimics.We report on the data analysis of the first 200 children seen in NOSC. A paediatric neurologist or paediatric/neurology trainee under supervision of a neurologist reviewed all the children. A detailed history and clinical examination were undertaken. Electroencephalogram (EEGs) were undertaken prior to clinic review in most emergency departments. Children were classified as 'epilepsy positive' (EP+) or 'epilepsy negative' (EP-) after the first consultation.Of 200 patients, 109 were classified as EP+: generalised epilepsy in 57 of 109, focal in 36, childhood seizure susceptibility syndrome in 26 and epileptic encephalopathy in 5. EEG was available in 192: in 117, it was abnormal - 23 with background abnormalities and 109 with epileptiform activity. Of the 109 patients, 80 were commenced on anti-epileptic drugs (AEDs): 12 were able to come off medication after seizure-free period, 61 were controlled on AEDs and 7 were refractory. Children were followed up for 12-48 months. None of the children had diagnosis revised on follow-up.This is the first Australian study to report on a large cohort of children from a NOSC. An EEG and a paediatric neurologist assessment is a good combination to enable diagnostic accuracy: In the first 200 patients seen, there were no revisions of the initial diagnosis on follow-up.
- Published
- 2017