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Kompjuterizovana tomografija (CT) je jedan od najznačajnijh dijagnostičkih modaliteta, čija upotreba raste iz decenije u deceniju. U ukupnom broju radioloških pregleda CT je zastupljena sa 5-10%, ali je njen doprinos ukupnoj dozi za populaciju veći od 50%. Osnovni pokazatelji kvaliteta slike i doza, kao i prateći radijacioni rizik zavise od primenjene radiografske tehnike odnosno CT pregleda. U smislu dobre radiološke prakse i u skladu sa osnovnim principima zaštite od zračenja, poželjna je primena najniže moguće doze za pacijenta uz održavanje kvaliteta slike i dijagnostičke informacije. Cilj istraživanja jeste definisanje optimalnog protokola pregleda višeslojnom CT za dijagnozu pojedinih regija tela, kao i da se utvrde doze i radijacioni rizik za pacijente pre i nakon optimizacije protokola. Analizom je obuhvaćeno ukupno 437 pacijenata, koji su podeljeni u grupe prema regijama tela koje su snimane: I–nekontrastni CT glave, II-CT glave sa i.v. kontrastom, III-CT grudnog koša, IV-CT abdomena i karlice i V-CT angio (CT angiografija aortoilijačnog segmenta i donjih ekstremiteta). Studija je izvedena u 2 faze: u I fazi je korišćen standardni protokol za regiju tela koja se snimala, a u II fazi CT pregledi su izvedeni po modifikovanom protokolu (promenom parametra vrednosti mAs), uz minimalne zahteve u pogledu kvaliteta slike.Na osnovu dozimetrijskih pokazatelja procenjena je efektivna doza i radijacioni rizik za pacijente u obe faze. U studiji su korišćene smernice iz Vodiča EUR 16262 EN, u kojima su definisani parametri za procenu kvaliteta slike da bi se analizirali različiti anatomski preseci određenih regija tela koji su se snimali. Kvalitet slike za svakog pacijenta je ocenjen pomoću trostepene skale vizualizacije za svaki parametar anatomske regije: 0-detalji su vidljivi, 1-detalji se prikazuju, 2-detalji se jasno prikazuju. Korišćena je subjektivna metoda gde su dva iskusna radiologa vršili interpretaciju slike. Konačna ocena kvaliteta slike svakog pregleda odgovara zbiru svih parametara procenjenih po trostepenoj skali vizualizacije. Zatim je za potrebe izračunavanja veličine FOM (figure of merit) izračunata vrednost indeksa ocene kvaliteta slike (zbir svih ocena parametra/brojem parametara). Vrednost FOM je izračunata kao količnik indeksa ocene kvaliteta slike i efektivne doza po pacijentu. Prosečna vrednost FOM za svaku grupu ispitanika nam je poslužila kao relativni pokazatelj za upoređivanje između neoptimizovane i optimizovane grupe ispitanika za isti tip pregleda. Poređenjem vrednosti efektivne doze u prvoj i drugoj fazi istraživanja kvantifikovano je smanjenje radijacionog opterećenja za pacijente nakon optimizacije protokola. Rezultati su pokazali da je optimalnim izborom protokola u smislu parametara ekspozicije (smanjenjem vrednosti mAs) moguće značajno smanjiti dozu zračenja kod pregleda glave za 7,5%, kod pregleda glave sa angiografijom za 7%, kod pregleda grudnog koša za 40%, kod pregleda abdomena i karlice za 25%. Grupa CT angio nije mogla da bude optimizovana, jer aparat nije prihvatao promenu kvaliteta slike kod zadatih parametara optimizacije. Primenom standardnih protokola postiže se kvalitet slike bolji nego što je neophodno, a samim tim i veća doza zračenja nego što je potrebno. Optimalnim izborom protokola u smislu parametara ekspozicije moguće je značajno smanjiti dozu zračenja, uz održavanje kvaliteta slike koji je dovoljan za adekvatnu radiološku interpretaciju slike. Computed tomography (CT) is one of the most significant diagnostic methods whose application has been increasing from decade to decade. Among the total number of radiological examinations CT accounts for 5-10%, however, its contribution in the whole dosage for the population is greater than 50%. Main indicator of the quality of images and dosages as well as the accompanying irradiation risk depend on applied radiographic technique that is CT examination. In the sense of good radiological practice and in accordance with basic principles of protection from irradiation, the application of the lowest possible dosage for a patient together with preserving the quality of image and diagnostic information are mostly welcomed. The goal of the research is to define the optimum examination protocol by multislice CT in diagnostics of certain body regions as well as to determine dosages and irradiation risk for patients both before and after protocol optimization. The analysis has included 437 patients divided into groups according to body regions which have been scanned: I-unenhanced head CT, II contrast enhanced head CT, III–chest CT, IV–abdomen and pelvis CT and V–angio CT (CT angiography of aortoiliac segment and lower extremities). The study has been conducted in 2 phases: in the first phase standard protocol for the scanned body region has been applied, and in the second phase CT examinations have been carried out according to the modified protocol (by change of parameters of values mAs) with minimum requirements regarding the image quality. On the basis of dosimetric indicators the efficient dosage and irradiation risk for the patients in both phases have been assessed. In the study the guidelines form the Guide EUR 16262 EN have been observed where parameters for the assessment of image quality have been defined in order to analyze different anatomic cross sections of certain body regions. Image quality for each patient was assessed by three-level visualization scale for each parameter of anatomic region: 0–details are visible, 1–details are presented, 2–details are clearly presented. A subjective method was applied where two experienced radiologists performed the image interpretation. Final assessment of image quality of every examination corresponds to the sum of all parameters according to three-level visualization scale. Further, for the need of calculation of the size of FOM (figure of merit) the value of the index of assessment of the image quality (sum of all assessments of parameters/number of parameters) has been calculated. The value of FOM has been calculated as a quotient of the image quality assessment index and effective dosage per patient. The average value of FOM for every group of patients has offered us a relative indicator for comparison of non-optimum and optimum group of patients for the same type of examinations. By comparison of values of effective dosage in the first and second phase of the research a decrease in irradiation load for patients after protocol optimization was quantified. The results have shown that by optimum protocol selection in the sense of exposition parameters (by reduction of values of mAs) it is possible to reduce significantly the irradiation dosage at unenhanced head CT examination for 7,5%, at contrast enhanced head CT examination for 7%, at chest CT examination for 40%, at abdomen and pelvis CT examination for 25%. The group CT angio could not be optimized since the device did not accept the change in image quality at set optimization parameters. By application of standard protocols the image quality better than required was achieved and along with this, a higher irradiation dosage occurred than required. By selection of protocol in the sense of exposition parameters it is possible to reduce irradiation dosage significantly along with preserving image quality which is sufficient for adequate radiological image interpretation.

Uvod: Termin - temporomandibularne disfunkcije (TMD) obuhvata veći broj oboljenja TMZ, mastikatorne muskulature i okolnih struktura. Epidemiološke studije pokazuju da 50-75% osoba u toku života ima neki znak poremećaja funkcije mastikatornog sistema. TMD se najčešće javljaju između 20-40 godine života. Najznačajniji znaci i simptomi TMD su bol u predelu maseteričnog mišića, TMZ, regiona temporalnog mišića, ograničeno otvaranje usta i zvučne pojave (kliktaji i krepitacije). Bol u predelu TMZ je najčešći razlog javljanja pacijenta lekaru. Cilj Utvrđivanje validnosti kliničkog nalaza TMD dobijenog korišćenjem RDC/TMD (engl. Research Diagnostic Criteria/ Temporomandibular Disorders) i nalaza na MR pregledu radi utvrđivanja prisustva disfunkcije u cilju blagovremenog i adekvatnog kliničkog zbrinjavanja. Istraživanje je sprovedeno kao prospektivna studija u Centru za Imidžing dijagnostiku, Institutu za Onkologiju Vojvodine u Sremskoj Kamenici, u periodu od januara 2011. do maja 2013. godine. Istraživanjem je obuhvaćeno 200 ispitanica (400TMZ) koje su došle na zakazani MR pregled endokranijuma nevezano za eventualnu patologiju TMZ tj. zbog neurološke simptomatologije. Ispitanicama je prvo snimljen MR endokranijuma zbog osnovnog oboljenja a zatim je pregled nastavljen snimanjem oba TMZ. Snimanje je izvedeno na aparatu Siemens (Erlangen, SR Nemačka) jačine magnetnog polja 3Tesla – Siemens AVANTO 3T, istog dana, nakon obavljenog kliničkog pregleda. Svakoj ispitanici urađen je parasagitalni (Slika 8) i koronalni presek TMZ kroz oba kondila sa sledećim parametrima snimanja: proton density sekvenca, vreme repeticije (TR) 1850 ms, vreme ehoa (TE) 15 ms, vidno polje (FOV) 13 cm, kao i matrica 128 x 256. Debljina preseka prilikom snimanja MR bila je manja od 2 mm. Prilikom snimanja svakoj ispitanici je bio stavljen osmokanalni zapreminski kalem (engl. head matrix coil) da bi signal u antero-posteriornom pravcu na dobijenim snimcima bio ujednačen. Ukupno vreme snimanja oba TMZ iznosilo je 4 minuta. Na osnovu MR pregleda, najveći broj TMZ je bio bez patoloških promena, njih 198 (49,5%). Prednja dislokacija diska sa redukcijom je ustanovljena kod 46 TMZ (11,5%), sledili su prednja dislokacija diska bez redukcije (18 TMZ (4,5%)), zadnja dislokacija 4 TMZ (1%) I osteoartritis kod 100 TMZ (25%)). Kombinacija poremećaja dislokacije diska sa redukcijom i osteoartritisa ustanovljena je kod 20 TMZ (5%), dislokacije diska bez redukcije i osteoartritisa kod 6 TMZ (1,5%), dok je kombinacija zadnje dislokacije i osteoartritisa detektovana kod 8 TMZ (2%). Rezultati Najčešći oblik diska bio je bikonkavan i identifikovan je kod 278 (69,5%) TMZ, slede biplanaran kod 76 (19%), hemikonveksan kod 20 (5%) i bikonveksan kod 14 TMZ (3,5%). Zaključak Na osnovu MR pregleda 51 % TMZ je imalo patološki nalaz. Korelacija dijagnoza postavljenih na osnovu RDC/TMD i MR pregleda pokazala je umereno dobro slaganje dijagnoza. MR pregled je detektovao dislokaciju diska kod 18% ispitanica koje nisu imale tegobe. Korelacija dijagnoza dislokacije diska postavljenih na osnovu RDC/TMD i MR pregleda je pokazala umereno dobro slaganje. Dijagnoza dislokacije diska sa i bez redukcije, na RDC/TMD ima visoku specifičnost i nisku senzitivnost u poređenju sa dijagnozom postavljenom na MR pregledu. Primenom RDC/TMD, postoji mala verovatnoća za postavljanje lažno pozitivne dijagnoza dislokacije diska sa i bez redukcije. Korelacija dijagnoza degenerativnih promena postavljenih na osnovu RDC/TMD i MR pregleda pokazala je slabo slaganje dijagnoza. RDC/TMD nije optimalna metoda za dijagnostiku degenerativnih promena temporomandibularnih zglobova. Introduction The term temporomandibular disorders (TMD) encompasses a large number of diseases of TMJ, masticatory musculature and surrounding structures. Epidemiological studies show that 50-75% of people have some type of impaired function of the masticatory system in the course of their lives. TMJ most commonly occurs between the ages of 20 to 40. The most important signs and symptoms of TMD are the pains in the area of masseter muscle; TMJ; temporal muscle; with limited mouth opening and sound phenomena (clicking and crepitus). Pain in the TMJ is the most common reason for a patient’s visit to a doctor. The aim To determine the validity of the clinical findings of TMD obtained by using RDC / TMD (Research Diagnostic Criteria / Temporomandibular Disorders) and MRI examination findings which could determine the presence of a disorder and therefore provide prompt and adequate clinical care. Materials and Methods The research was conducted as a prospective study at the Diagnostic Imaging Center, Oncology Institute of Vojvodina in Sremska Kamenica in the period from January 2011 to May 2013. The study included 200 subjects (400 TMJs) who came for a scheduled MRI of endocranium not related to potential TMJ pathology i.e. having neurological symptoms. Firstly, the subjects underwent the MRI of the endocranium due to their underlying diseases and then the examination continued with MRI of both TMJs. The imaging was performed using Siemens device (Erlangen, Germany) with the magnetic field strength 3Tesla - Siemens Avanto 3T the same day after their clinical examination. Each subject underwent a parasagital and coronal cross section of TMJ through both condyles with the following imaging parameters: proton density sequence, repetition time (TR) 1850 ms, echo time (TE) 15 ms, field of view (FOV) 13 cm and a matrix of 128 x 256. The section thickness during MRI was less than 2 mm. During imaging, 8-channel head matrix coil was placed on each subject so that the signal in antero-posterior direction at the obtained images was uniform. Total imaging time for both TMJs was 4 minutes. Results Based on the MRI examination, the largest number of TMJs had no pathological changes - 198 of them (49.5%). Anterior disc displacement with reduction was found in 46 TMJs (11.5%), followed by the anterior disc displacement without reduction (18 TMJs (4.5%)), posterior displacement of TMJ 4 (1%) and osteoarthritis in 100 TMJs (25 %)). The combination of disorders of disc displacement with reduction and osteoarthritis was found in 20 TMJs (5%), disc displacement without reduction and osteoarthritis in 6 TMJs (1.5%), while the combination of the posterior displacement and osteoarthritis was found in 8 TMJs (2%). The most common shape of a disc was biconcave and was identified in 278 (69.5%) TMJs, followed by biplanar in 76 (19%), hemiconvex 20 (5%) and biconvex in 14 TMJs (3.5%). Conclusion Based on the MRI examination, 51% of TMJs had pathological findings. Correlation of diagnoses which was determined based on RDC / TMD and MRI examination was moderately present. MRI examination detected disc displacement in 18% of subjects who did not have any problems. Correlation of diagnoses of disc displacement which was determined based on RDC / TMD and MRI examination showed moderately good results. The diagnosis of disc displacement with and without reduction on the RDC / TMD has a high specificity and low sensitivity compared with the diagnosis from the MRI examination. When applying the RDC / TMD there is little chance of setting a false positive diagnosis of disc displacement with and without reduction. The correlation of the degenerative changes diagnoses which were set based on the RDC / TMD and MRI examination showed poor results. RDC / TMD is not an optimal method for the diagnosing the degenerative changes of temporomandibular joints.

Uvod: Termin - temporomandibularne disfunkcije (TMD) obuhvata veći broj oboljenja TMZ, mastikatorne muskulature i okolnih struktura. Epidemiološke studije pokazuju da 50-75% osoba u toku života ima neki znak poremećaja funkcije mastikatornog sistema. TMD se najčešće javljaju između 20-40 godine života. Najznačajniji znaci i simptomi TMD su bol u predelu maseteričnog mišića, TMZ, regiona temporalnog mišića, ograničeno otvaranje usta i zvučne pojave (kliktaji i krepitacije). Bol u predelu TMZ je najčešći razlog javljanja pacijenta lekaru. Cilj Utvrđivanje validnosti kliničkog nalaza TMD dobijenog korišćenjem RDC/TMD (engl. Research Diagnostic Criteria/ Temporomandibular Disorders) i nalaza na MR pregledu radi utvrđivanja prisustva disfunkcije u cilju blagovremenog i adekvatnog kliničkog zbrinjavanja. Istraživanje je sprovedeno kao prospektivna studija u Centru za Imidžing dijagnostiku, Institutu za Onkologiju Vojvodine u Sremskoj Kamenici, u periodu od januara 2011. do maja 2013. godine. Istraživanjem je obuhvaćeno 200 ispitanica (400TMZ) koje su došle na zakazani MR pregled endokranijuma nevezano za eventualnu patologiju TMZ tj. zbog neurološke simptomatologije. Ispitanicama je prvo snimljen MR endokranijuma zbog osnovnog oboljenja a zatim je pregled nastavljen snimanjem oba TMZ. Snimanje je izvedeno na aparatu Siemens (Erlangen, SR Nemačka) jačine magnetnog polja 3Tesla – Siemens AVANTO 3T, istog dana, nakon obavljenog kliničkog pregleda. Svakoj ispitanici urađen je parasagitalni (Slika 8) i koronalni presek TMZ kroz oba kondila sa sledećim parametrima snimanja: proton density sekvenca, vreme repeticije (TR) 1850 ms, vreme ehoa (TE) 15 ms, vidno polje (FOV) 13 cm, kao i matrica 128 x 256. Debljina preseka prilikom snimanja MR bila je manja od 2 mm. Prilikom snimanja svakoj ispitanici je bio stavljen osmokanalni zapreminski kalem (engl. head matrix coil) da bi signal u antero-posteriornom pravcu na dobijenim snimcima bio ujednačen. Ukupno vreme snimanja oba TMZ iznosilo je 4 minuta. Na osnovu MR pregleda, najveći broj TMZ je bio bez patoloških promena, njih 198 (49,5%). Prednja dislokacija diska sa redukcijom je ustanovljena kod 46 TMZ (11,5%), sledili su prednja dislokacija diska bez redukcije (18 TMZ (4,5%)), zadnja dislokacija 4 TMZ (1%) I osteoartritis kod 100 TMZ (25%)). Kombinacija poremećaja dislokacije diska sa redukcijom i osteoartritisa ustanovljena je kod 20 TMZ (5%), dislokacije diska bez redukcije i osteoartritisa kod 6 TMZ (1,5%), dok je kombinacija zadnje dislokacije i osteoartritisa detektovana kod 8 TMZ (2%). Rezultati Najčešći oblik diska bio je bikonkavan i identifikovan je kod 278 (69,5%) TMZ, slede biplanaran kod 76 (19%), hemikonveksan kod 20 (5%) i bikonveksan kod 14 TMZ (3,5%). Zaključak Na osnovu MR pregleda 51 % TMZ je imalo patološki nalaz. Korelacija dijagnoza postavljenih na osnovu RDC/TMD i MR pregleda pokazala je umereno dobro slaganje dijagnoza. MR pregled je detektovao dislokaciju diska kod 18% ispitanica koje nisu imale tegobe. Korelacija dijagnoza dislokacije diska postavljenih na osnovu RDC/TMD i MR pregleda je pokazala umereno dobro slaganje. Dijagnoza dislokacije diska sa i bez redukcije, na RDC/TMD ima visoku specifičnost i nisku senzitivnost u poređenju sa dijagnozom postavljenom na MR pregledu. Primenom RDC/TMD, postoji mala verovatnoća za postavljanje lažno pozitivne dijagnoza dislokacije diska sa i bez redukcije. Korelacija dijagnoza degenerativnih promena postavljenih na osnovu RDC/TMD i MR pregleda pokazala je slabo slaganje dijagnoza. RDC/TMD nije optimalna metoda za dijagnostiku degenerativnih promena temporomandibularnih zglobova., Introduction The term temporomandibular disorders (TMD) encompasses a large number of diseases of TMJ, masticatory musculature and surrounding structures. Epidemiological studies show that 50-75% of people have some type of impaired function of the masticatory system in the course of their lives. TMJ most commonly occurs between the ages of 20 to 40. The most important signs and symptoms of TMD are the pains in the area of masseter muscle; TMJ; temporal muscle; with limited mouth opening and sound phenomena (clicking and crepitus). Pain in the TMJ is the most common reason for a patient’s visit to a doctor.The aim To determine the validity of the clinical findings of TMD obtained by using RDC / TMD (Research Diagnostic Criteria / Temporomandibular Disorders) and MRI examination findings which could determine the presence of a disorder and therefore provide prompt and adequate clinical care.Materials and Methods The research was conducted as a prospective study at the Diagnostic Imaging Center, Oncology Institute of Vojvodina in Sremska Kamenica in the period from January 2011 to May 2013. The study included 200 subjects (400 TMJs) who came for a scheduled MRI of endocranium not related to potential TMJ pathology i.e. having neurological symptoms. Firstly, the subjects underwent the MRI of the endocranium due to their underlying diseases and then the examination continued with MRI of both TMJs. The imaging was performed using Siemens device (Erlangen, Germany) with the magnetic field strength 3Tesla - Siemens Avanto 3T the same day after theirclinical examination. Each subject underwent a parasagital and coronal cross section of TMJ through both condyles with the following imaging parameters: proton density sequence, repetition time (TR) 1850 ms, echo time (TE) 15 ms, field of view (FOV) 13 cm and a matrix of 128 x 256. The section thickness during MRI was less than 2 mm. During imaging, 8-channel head matrix coil was placed on each subject so that the signal in antero-posterior direction at the obtained images was uniform. Total imaging time for both TMJs was 4 minutes.Results Based on the MRI examination, the largest number of TMJs had no pathological changes - 198 of them (49.5%). Anterior disc displacement with reduction was found in 46 TMJs (11.5%), followed by the anterior disc displacement without reduction (18 TMJs (4.5%)), posterior displacement of TMJ 4 (1%) and osteoarthritis in 100 TMJs (25 %)). The combination of disorders of disc displacement with reduction and osteoarthritis was found in 20 TMJs (5%), disc displacement without reduction and osteoarthritis in 6 TMJs (1.5%), while the combination of the posterior displacement and osteoarthritis was found in 8 TMJs (2%). The most common shape of a disc was biconcave and was identified in 278 (69.5%) TMJs, followed by biplanar in 76 (19%), hemiconvex 20 (5%) and biconvex in 14 TMJs (3.5%).Conclusion Based on the MRI examination, 51% of TMJs had pathological findings. Correlation of diagnoses which was determined based on RDC / TMD and MRI examination was moderately present. MRI examination detected disc displacement in 18% of subjects who did not have any problems. Correlation of diagnoses of disc displacement which was determined based on RDC / TMD and MRI examination showed moderately good results. The diagnosis of disc displacement with andwithout reduction on the RDC / TMD has a high specificity and low sensitivity compared with the diagnosis from the MRI examination. When applying the RDC / TMD there is little chance of setting a false positive diagnosis of disc displacement with and without reduction. The correlation of the degenerative changes diagnoses which were set based on the RDC / TMD and MRI examination showed poor results. RDC / TMD is not an optimal method for the diagnosing the degenerative changes of temporomandibular joints.

Uvod: Hronični subduralni hematom (HSDH) je učestala i nezanemarljiva traumatska/netraumatska intrakranijalna lezija, naročito kod pacijenata starije životne dobi. Simptomi pacijenata sa HSDH su raznovrsni i često pogrešno protumačeni i lečeni. Zbog navedenih činjenica, HSDH predstavlja veliki izazov u dijagnostici i terapiji. Različiti autori ističu značaj radioloških parametara tokom dijagnostike ovog oboljenja i povezanost sa kliničkom slikom I neurološkim statusom pacijenta, pa je ovo istraživanje bilo usmereno u preciznoj evaluaciji pomenutih parametara, njihovoj prediktivnoj vrednosti i uticaju na prognozu ishoda lečenja. Cilj: Generalni cilj istraživanja je bio da se ispita učestalost pacijenata sa hroničnim subduralnim hematomom na teritoriji Vojvodine u periodu od tri godine; da se analizira starosna dob pacijenata, polna distribucija oboljenja, uticaj komorbiditeta ili faktora rizika na nastanak HSDH; prisustvo ili odsustvo traume koja je doprinela nastanku HSDH, vremenski interval od traume do pojave simpotoma ili znakova bolesti i da se omogući praćenje efekta terapije pacijenata sa ovim oboljenjem. Specifični ciljevi su obuhvatili: 1. Da se utvrde parametri kompjuterizovane tomografije koji imaju prediktivni značaj u pozitivnom ishodu lečenja pacijenata sa hroničnim subduralnim hematomom. 2. Da se utvrde klinički parametri koji imaju prediktivni značaj u pozitivnom ishodu lečenja pacijenata sa hroničnim subduralnim hematomom. 3. Da se dobije model sa najvećom specifičnošću i senzitivnošću za predikciju ishoda lečenja, kombinacijom kliničkih i parametrara kompjuterizovane tomografije kod pacijenata sa hroničnim subduralnim hematomom. Materijal i metode: Istraživanje je obavljeno kao prospektivna trogodišnja studija u periodu od aprila 2010. do aprila 2013. godine u Kliničkom Centru Vojvodine- Centru za radiologiju i Klinici za neurohirurgiju i obuvatila je 83 pacijenata sa dijagnozom hroničnog subduralnog hematoma. Svi ispitanici su dijagnostikovani upotrebom kompjuterizovane tomografije glave (CT) i lečeni na Klinici za neurohirurgiju KCV. Izvori podataka su celokupna medicinska dokumentacija svakog pacijenta od perioda prve hospitalizacije do njihovog otpusta, a uključuje i podatke vezane za subjektivni osećaj o zdravstvenom stanju koje su pacijenti usmeno izneli šest meseci nakon hospitalnog otpusta. Rezultati: Rezultati istraživanja pokazuju da je Glasgow Coma Scala (GCS) tj. nivo svesti pacijenta na hospitalnom prijemu jedini parametar sa visokom prediktivnom vrednošću za klinički ishod lečenja pacijenata sa HSDH procenjen preko Glasgow Outcome Scale (GOS). Preostali radiološki i klinički parametri (širina hematoma, pomeraj mediosagitalne linije, denzitet hematoma, starost pacijenta) nemaju visoku prediktivnu vrednost za klinički ishod pacijenata sa hroničnim subduralnim hematomom. Zaključak: Na osnovu grupe analiziranih pacijenata sa HSDH nije bilo moguće napraviti optimalan model za predikciju ishoda lečenja kombinujući radiološke i kliničke parametre. Pojedinačno posmatrani radiološki parametri nisu imali visoku prediktivnu vrednost za ishod lečenja pacijenata sa HSDH. Izolovan klinički parametar- GCS- je jedini visoko prediktivni faktor za ishod lečenja pacijenata sa HSDH. Kombinacija kliničkih i radioloških parametara daje visoku vrednost predviđanja kliničkog ishoda lečenja, ali samo zahvaljujući izrazito visokoj prediktivnoj vrednosti GCS. Iz svega navedenog, kompjuterizovana tomografija (CT) ima veliki značaj u ranoj dijagnostici i praćenju terapije pacijenata sa HSDH, ali CT parametri ponaosob nemaju značaj u predviđanju ishoda lečenja., Introduction: Chronic subdural hematoma (CSDH) is common traumatic/no traumatic intracranial lesion, especially in older patients. Symptomatology of this disease is variable and often is misdiagnosed and treated with specially challenges in diagnostic and therapy. Different authors pointed on importance of radiological parameters during diagnostic of this disease and connections with clinic and neurological status in patients with chronic subdural hematoma (CSDH), so this thesis was directed to evaluate radiological and clinical parameters of CSDHs and to show their predictive values and their significance on patient’s outcome. Aim: General aim of this thesis was to examine frequency of patients with chronic subdural hematoma in Vojvodina, during the period of three years, to analyze the age of population with CSDHs, the gender distribution, an impact of comorbidity or risk factors for patients with CSDHs, the presence or absence of trauma which has contributed to CSDH, to determine time interval from trauma to appearance of symptoms and signs of disease, monitoring the effect of therapy. Specific aims were: 1. To determine clinical parameters with a positive predictive significance on patients outcome 2. To determine radiological parameters with a positive predictive significance on patients outcome 3. To determine optimal prognostic model with high specificity and sensitivity, using combination of radiological and clinical parameters for positive prediction outcome. Material and methods: The study was performed as three-year prospective study from April 2010 to April 2013 in Clinical Centre of Vojvodina, Centre for Radiology and Clinic of Neurosurgery and includes 83 patients with chronic subdural hematoma. All patients were diagnosed using computed tomography of the brain (CT scan) and all were treated in Clinic of Neurosurgery (KCV). Data sources included the medical records of each patient from the time of first hospitalization to period of their discharge and included data related to the subjective feeling of the health that patients verbally present six months after hospital discharge. Results: The results showed that the Glasgow Coma Scale (GCS) - a level of consciousness of the patient on the hospital admission was the only parameter with a high predictive value for clinical outcome of patients with CSDH assessed through Glasgow Outcome Scale (GOS). Other evaluated radiological and clinical parameters (width of the CSDH, mediosagital line displacement, a density of the CSDH, the age of the patient) did not have high predictive values for the clinical outcome in patients with chronic subdural hematoma. Conclusion: Based on the analyzed group of patients with CSDH it was not possible to make optimal predictive model for outcome by combining radiological and clinical parameters. Radiographic parameters did not have high predictive values for treatment outcome in patients with CSDH. Glasgow Coma Scale (GCS) is the only highly predictive factor for treatment outcome in patients with CSDH. The combination of clinical and radiological parameters gives high predictive value for clinical outcome, but only because of extremely high predictive value of GCS. Therefore, computed tomography (CT) is of great importance in early diagnosis and therapy monitoring of patients with CSDH, but CT parameters did not have the high predictive values for the patient’s clinical outcome.