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47,067 results on '"Pneumonia, Viral"'

58. Simple, Safe, Same: Lung Ultrasound for COVID-19 (LUSCOVID19)

Author

Valle del Serchio General Hospital, Lucca, Italy, Università degli Studi di Trento, Fondazione IRCCS Policlinico San Matteo, University of Pavia, Pavia, Italy, Bresciamed, Brescia, Italy, 118 USL Nordovest Toscana, Lucca, Italy, General Hospital, Voghera, Italy, Lodi General Hospital, Lodi, Italy, and Riccardo Inchingolo, Principal Investigator

Published
2022

71. Predictors of prolonged ventilator weaning and mortality in critically ill patients with COVID-19

Author

Marcella M Musumeci, Bruno Valle Pinheiro, Luciana Dias Chiavegato, Danielle Silva Almeida Phillip, Flavia R Machado, Fabrício Freires, Osvaldo Shigueomi Beppu, Jaquelina Sonoe Ota Arakaki, and Roberta Pulcheri Ramos

Subjects
COVID-19, Pneumonia, viral, Respiratory distress syndrome, Respiration, artificial, Ventilator weaning, Cohort studies, Hospital mortality, Patient outcome assessment, Diseases of the respiratory system, RC705-779
Abstract

ABSTRACT Objective: To identify factors associated with prolonged weaning and mortality in critically ill COVID-19 patients admitted to ICUs and under invasive mechanical ventilation. Methods: Between March of 2020 and July of 2021, we retrospectively recorded clinical and ventilatory characteristics of critically ill COVID-19 patients from the day of intubation to the outcome. We classified the patients regarding the weaning period in accordance with established criteria. A logistic regression analysis was performed to identify variables associated with prolonged weaning and mortality. Results: The study involved 303 patients, 100 of whom (33.0%) had a prolonged weaning period. Most of the patients were male (69.6%), 136 (44.8%) had more than 50% of pulmonary involvement on chest CT, and 93 (30.6%) had severe ARDS. Within the prolonged weaning group, 62% died within 60 days. Multivariate analysis revealed that lung involvement greater than 50% on CT and delay from intubation to the first separation attempt from mechanical ventilation were significantly associated with prolonged weaning, whereas age and prolonged weaning were significantly associated with mortality. Conclusions: Prolonged weaning can be used as a milestone in predicting mortality in critically ill COVID-19 patients. Lung involvement greater than 50% on CT and delay from intubation to the first separation attempt from mechanical ventilation were identified as significant predictors of prolonged weaning. These results might provide valuable information for healthcare professionals when making clinical decisions regarding the management of critically ill COVID-19 patients who are on mechanical ventilation.

Published
2023
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72. Escala pronóstica para mortalidad intrahospitalaria en pacientes con neumonía viral COVID-19.

Author

José Molina-Pérez, Carlos, Guadalupe Berumen-Lechuga, María, Leaños-Miranda, Alfredo, Rafael SánchezMejía, Eduardo, Gasca-Martínez, Víctor, and Fernández-Méndez, Jacqueline

Abstract

Background: The COVID-19 pandemic represented a challenge in medical care. A tool would be very useful to establish the prognosis of in-hospital death that is reliable and can be applied to the Mexican population entitled to the IMSS. Objective: To propose a prognostic scale to stratify patients with viral pneumonia COVID-19 in the emergency services. Material and methods: A nested case-control study was conducted in a cohort of patients who were consecutively admitted to the emergency department with viral pneumonia COVID-19. The cases were those patients who died, and the controls were those who were discharged due to health improvement. An association analysis was performed between the variables with significant differences between groups. Subsequently, the association was adjusted using a multivariate logistic regression model, from which the prognostic scale was developed. Results: A total of 70 subjects with COVID-19 were included, 34 cases and 36 controls. Chronic diseases, smoking, severe pulmonary involvement diagnosed by tomography, leukocytosis, and pulse oximetry less than 80% with were associated with in-hospital mortality; Odds Ratio (OR) of >1.1. Vaccination was a protective factor (OR = 0.04, CI95%: 0.01-0.16). A score greater than 3 points on the prognostic scale predicts in-hospital mortality with a specificity of 0.86 and a sensitivity of 0.73. Conclusions: The proposed prognostic scale can be a useful tool in the classification of patients with COVID-19 viral pneumonia in the emergency room services of secondary care level Hospitals. [ABSTRACT FROM AUTHOR]

Published
2023
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77. Nitazoxanide Therapy for Patients With COVID-19 Pneumonia

Author

Ministry of Science and Technology, Brazil, National Research Council, Brazil, Financiadora de Estudos e Projetos, ATCGen, Hospital Central da Aeronáutica, Rio de Janeiro, Hospital da Força Aérea do Galeão, Hospital Naval Marcilio Dias, Hospital Universitario Pedro Ernesto, Hospital de Força Aérea de São Paulo, Hospital das Clínicas Luzia de Pinho Melo, Complexo Hospitalar Municipal de São Caetano do Sul, Hospital Municipal de Barueri Dr Francisco Moran, Hospital Regional de Sorocaba Dr Adib Domingos Jatene, Hospital Geral de São Mateus Dr Manoel Bifulco, Santa Casa de Misericórdia de Belo Horizonte, Mater Dei Hospital, Brazil, Hospital Eduardo de Menezes, Hospital das Clínicas da Universidade Federal de Pernambuco, Hospital das Forças Armadas, Brazil, Hospital Regional da Asa Norte, Brazil, Complexo Hospitalar do Trabalhador de Curitiba, Hospital Estadual de Doenças Tropicais Dr Anuar Auad, Hospital Geral de Fortaleza, and Jose Roberto Lapa e Silva, Clinical Investigator

Published
2021

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