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51. Revisional Surgery After One Anastomosis/Minigastric Bypass: an Italian Multi-institutional Survey

Author

Musella, Mario, Vitiello, Antonio, Susa, Antonio, Greco, Francesco, De Luca, Maurizio, Manno, Emilio, Olmi, Stefano, Raffaelli, Marco, Lucchese, Marcello, Carandina, Sergio, Foletto, Mirto, Pizza, Francesco, Bardi, Ugo, Navarra, Giuseppe, Schettino, Angelo Michele, Gentileschi, Paolo, Sarro, Giuliano, Chiappetta, Sonja, Tirone, Andrea, Berardi, Giovanna, Velotti, Nunzio, Foschi, Diego, Zappa, Marco, and Piazza, Luigi

Published
2022
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52. Management of endocrine surgical disorders during COVID-19 pandemic: expert opinion for non-surgical options

Author

Agcaoglu, Orhan, Sezer, Atakan, Makay, Ozer, Erdogan, Murat Faik, Bayram, Fahri, Guldiken, Sibel, Raffaelli, Marco, Sonmez, Yusuf Alper, Lee, Yong-Sang, Vamvakidis, Kyriakos, Mihai, Radu, Duh, Quan-Yang, Akinci, Baris, Alagol, Faruk, Almquist, Martin, Barczynski, Marcin, Bayraktaroglu, Taner, Berber, Eren, Bukey, Yusuf, Cakmak, Guldeniz Karadeniz, Canturk, Nuh Zafer, Canturk, Zeynep, Celik, Mehmet, Celik, Ozlem, Ceyhan, Banu Ozturk, Cherenko, Sergii, Clerici, Thomas, Coombes, David Scott, Demircan, Orhan, Deyneli, Oguzhan, Dionigi, Gianlorenzo, Emre, Ali Ugur, Erbil, Yesim, Filiz, Ali Ilker, Gozu, Hulya Ilıksu, Gurdal, Sibel Ozkan, Gurleyik, Gunay, Haciyanli, Mehmet, Kebudi, Abut, Kim, Seokmo, Koutelidakis, Giannis, Kuru, Bekir, Mert, Meral, Oruk, Guzide Gonca, Ozbas, Serdar, Palazzo, Fausto, Pandev, Rumen, Riss, Phillip, Sabuncu, Tevfik, Sahin, Ibrahim, Sakman, Gurhan, Saygili, Fusun, Senyurek, Yasemin Giles, Sleptsov, Ilya, Van Slycke, Sam, Teksoz, Serkan, Terzioglu, Tarik, Tezelman, Serdar, Tunca, Fatih, Ugurlu, Mustafa Umit, Uludag, Mehmet, Villar-del-Moral, Jesus, Vriens, Menno, and Yazici, Dilek

Published
2022
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53. Characterization of gut microbiota in patients with metabolic syndrome candidates for bariatric/metabolic surgery: Preliminary findings of a multi-center prospective study

Author

De Maio, Flavio, Boru, Cristian Eugeniu, Avallone, Marcello, Velotti, Nunzio, Bianco, Delia Mercedes, Capoccia, Danila, Greco, Francesco, Guarisco, Gloria, Nogara, Manuela, Sanguinetti, Maurizio, Verrastro, Ornella, Capaldo, Brunella, Musella, Mario, Raffaelli, Marco, Delogu, Giovanni, Silecchia, Gianfranco, and Leonetti, Frida

Published
2021
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54. A simplified primary aldosteronism surgical outcome score is a useful prediction model when target organ damage is unknown – Retrospective cohort study

Author

Zarnegar, Rasa, Fahey, Thomas J., Duh, Quan Y., Shen, Wen T., Drake, Frederick T., McAneny, David B., McManus, Catherine, Lee, James A., Grant, Scott B., Grogan, Raymon H., Romero Arenas, Minerva A., Perrier, Nancy D., Sturgeon, Cord, Castelino, Tanya, Mitmaker, Elliot J., Parente, David N., Pasternak, Jesse D., Sidhu, Stan B., Sywak, Mark, D'Amato, Gerardo, Raffaelli, Marco, Schuermans, Valerie, Bouvy, Nicole D., Eker, Hasan H., Bonjer, H. Jaap, Engelsman, Anton F., van Dijkum, Els J.M. Nieveen, Kerstens, Michiel N., Kruijff, Schelto, Suurd, Diederik P.D., Visscher, Wouter P., Vorselaars, Wessel M.C.M., van Beek, Dirk-Jan, Spiering, Wilko, Borel Rinkes, Inne H.M., Valk, Gerlof D., and Vriens, Menno R.

Published
2021
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58. Machine Learning-Based Algorithm for the Early Prediction of Postoperative Hypocalcemia Risk After Thyroidectomy.

Author

Muller, Olivier, Bauvin, Pierre, Bacoeur, Ophélie, Michailos, Théo, Bertoni, Maria-Vittoria, Demory, Charles, Marciniak, Camille, Chetboun, Mikael, Baud, Grégory, Raffaelli, Marco, Caiazzo, Robert, and Pattou, Francois

Abstract

Objective: We used machine learning to develop and validate a multivariable algorithm allowing the accurate and early prediction of postoperative hypocalcemia risk. Background: Postoperative hypocalcemia is frequent after total thyroidectomy. An early and accurate individualized prediction of the risk of hypocalcemia could guide the selective prescription of calcium supplementation only to patients most likely to present with hypocalcemia after total thyroidectomy. Methods: This retrospective study enrolled all patients undergoing total thyroidectomy in a single referral center between November 2019 and March 2022 (derivation cohort) and April 2022 and September 2022 (validation cohort). The primary study outcome was postoperative hypocalcemia (serum calcium under 80 mg/L). Exposures were multiple clinical and biological variables prospectively collected and analyzed with various machine learning methods to develop and validate a multivariable prediction algorithm. Results: Among 610/118 participants in the derivation/validation cohorts, 100 (16.4%)/26 (22%) presented postoperative hypocalcemia. The most accurate prediction algorithm was obtained with random forest and combined intraoperative parathyroid hormone measurements with 3 clinical variables (age, sex, and body mass index) to calculate a postoperative hypocalcemia risk for each patient. After multiple cross-validation, the area under the receiver operative characteristic curve was 0.902 (0.829--0.970) in the derivation cohort, and 0.928 (95% CI: 0.86; 0.97) in the validation cohort. Postoperative hypocalcemia risk values of 7% (low threshold) and 20% (high threshold) had, respectively, a sensitivity of 92%, a negative likelihood ratio of 0.11, a specificity of 90%, and a positive of 7.6 for the prediction of postoperative hypocalcemia. Conclusions: Using machine learning, we developed and validated a simple multivariable model that allowed the accurate prediction of postoperative hypocalcemia. The resulting algorithm could be used at the point of care to guide clinical management after total thyroidectomy. [ABSTRACT FROM AUTHOR]

Published
2024
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60. Locoregional vs. General Anaesthesia for Minimally Invasive Video-Assisted Parathyroidectomy (MIVAP) Using Propensity Score Matching Analysis: A Feasibility Study

Author

Pennestrì, Francesco, primary, Procopio, Priscilla Francesca, additional, Prioli, Francesca, additional, Gallucci, Pierpaolo, additional, Sessa, Luca, additional, Martullo, Annamaria, additional, Laurino, Antonio, additional, Revelli, Luca, additional, Modesti, Cristina, additional, De Crea, Carmela, additional, and Raffaelli, Marco, additional

Published
2024
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61. Consensus statement of the European Society of Endocrine Surgeons (ESES) on advanced parathyroid cancer: definitions and management

Author

Makay, Özer, primary, Agcaoglu, Orhan, additional, Nominé-Criqui, Claire, additional, Van Den Heede, Klaas, additional, Staubitz-Vernazza, Julia I, additional, Pennestrì, Francesco, additional, Brunaud, Laurent, additional, Raffaelli, Marco, additional, Iacobone, Maurizio, additional, Van Slycke, Sam, additional, Musholt, Thomas J, additional, and Villar-del-Moral, Jesús, additional

Published
2024
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62. Obesity Surgery Mortality Risk Score as a Predictor for Intensive Care Unit Admission in Patients Undergoing Laparoscopic Bariatric Surgery

Author

Aceto, Paola, primary, De Cicco, Roberto, additional, Calabrese, Claudia, additional, Marusco, Irene, additional, Del Tedesco, Filippo, additional, Luca, Ersilia, additional, Modesti, Cristina, additional, Sacco, Teresa, additional, Sollazzi, Liliana, additional, Ciccoritti, Luigi, additional, Greco, Francesco, additional, Giustacchini, Piero, additional, Pennestrì, Francesco, additional, Gallucci, Pierpaolo, additional, and Raffaelli, Marco, additional

Published
2024
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63. Complications and mortality in a cohort of patients undergoing emergency and elective surgery with perioperative SARS-CoV-2 infection: an Italian multicenter study. Teachings of Phase 1 to be brought in Phase 2 pandemic

Author

De Luca, Maurizio, Sartori, Alberto, Vitiello, Antonio, Piatto, Giacomo, Noaro, Giulia, Olmi, Stefano, Foschi, Diego, De Re, Luca, Zappa, Marco, Sarro, Giuliano, Rivolta, Umberto, Giraudo, Giorgio, Borghi, Felice, Pozzo, Gabriele, Sorisio, Vincenzo, Pignata, Giusto, Greco, Paola Antonella, Sisti, Valerio, Campagnaro, Tommaso, Guglielmi, Alfredo, Andreuccetti, Jacopo, Di Leo, Alberto, Lauro, Enrico, Ricci, Francesco, Musella, Mario, Zizzo, Maurizio, Bonacini, Stefano, Podda, Mauro, Pisanu, Adolfo, Coletta, Pietro, Guerrieri, Mario, Caracino, Valerio, Basti, Massimo, Pilone, Vincenzo, Raffaelli, Marco, and Oragano, Luigi

Published
2021
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65. Correction: Advice of General Practitioner, of Surgeon, of Endocrinologist, and Self-Determination: the Italian Road to Bariatric Surgery

Author

Pontiroli, Antonio E., Mingrone, Geltrude, Colao, Annamaria, Barrea, Luigi, Cannavale, Giulia, Pinna, Ferdinando, Ceriani, Valerio, De Carli, Stefano Maria, Cesana, Giovanni, Olmi, Stefano, Scolari, Gloria, Sarro, Simonetta, Sarro, Giuliano, Procopio, Claudia, Giovanelli, Alessandro, Morricone, Lelio, Micheletto, Giancarlo, Malavazos, Alexis, Panizzo, Valerio, Plebani, Laura, Zappa, Marco Antonio, Tubazio, Igor, Foschi, Diego, Capogrossi, Silvia, Conte, Caterina, Saibene, Alessandro, Socci, Carlo, Gozza, Martina, Testa, Sara, Marinari, Giuseppe, Maccatrozzo, Stefano, Croci, Marina, Mozzi, Enrico, Verrastro, Ornella, Capristo, Esmeralda, Raffaelli, Marco, Bruni, Vincenzo, Soare, Andrea, Spagnolo, Giuseppe, Manfrini, Silvia, Gallo, Ida, Casella, Giovanni, Gissey, Lidia Castagneto, Watanabe, Mikiko, Frontoni, Simona, Di Paola, Massimiliano, Russo, Benedetta, Bigarelli, Patrizia, Mariolo, James R. Casella, Filippi, Franca, Leonetti, Frida, Di Biasio, Alberto, Silecchia, Gianfranco, Guglielmi, Valeria, Arcudi, Claudio, Gentileschi, Paolo, Sbraccia, Paolo, Vitiello, Antonio, Musella, Mario, Schiano, Rita, Giardiello, Cristiano, Iovino, Michele Giuseppe, De Palma, Maurizio, Tolone, Salvatore, Docimo, Ludovico, Renzulli, Michele, Pilone, Vincenzo, Police, Maria, Angrisani, Luigi, and Tagliabue, Elena

Published
2022
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67. European Society of Endocrine Surgeons (ESES) consensus statement on advanced thyroid cancer: Definitions and management

Author

Heelkunde Opleiding, MS CGO, Cancer, Raffaelli, Marco, Voloudakis, Nikolaos, Barczynski, Marcin, Brauckhoff, Katrin, Durante, Cosimo, Gomez-Ramirez, Joaquin, Koutelidakis, Ioannis, Lorenz, Kerstin, Makay, Ozer, Materazzi, Gabriele, Pandev, Rumen, Randolph, Gregory W., Tolley, Neil, Vriens, Menno, Musholt, Thomas, Heelkunde Opleiding, MS CGO, Cancer, Raffaelli, Marco, Voloudakis, Nikolaos, Barczynski, Marcin, Brauckhoff, Katrin, Durante, Cosimo, Gomez-Ramirez, Joaquin, Koutelidakis, Ioannis, Lorenz, Kerstin, Makay, Ozer, Materazzi, Gabriele, Pandev, Rumen, Randolph, Gregory W., Tolley, Neil, Vriens, Menno, and Musholt, Thomas

Published
2024

68. Neuromonitoraggio continuo in chirurgia tiroidea

Author

Dionigi, Gianlorenzo, Calò, Pier Giorgio, Materazzi, Gabriele, Iacobone, Maurizio, Innaro, Nadia, De Palma, Maurizio, Pezzullo, Luciano, Chiofalo, Maria Grazia, Zaccaroni, Alberto, Pino, Antonella, Carcoforo, Paolo, D’Amore, Annamaria, De Crea, Carmela, Avenia, Nicola, Raffaelli, Marco, Conzo, Giovanni, Del Rio, Paolo, Docimo, Giovanni, Testini, Mario, and Lombardi, Celestino Pio

Published
2020
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71. Neuromonitoraggio intraoperatorio in chirurgia tiroidea: considerazioni nell’ambito della Società Italiana Unitaria Endocrinochirurgia (SIUEC)

Author

Dionigi, Gianlorenzo, Calò, Pier Giorgio, Materazzi, Gabriele, Iacobone, Maurizio, Innaro, Nadia, De Palma, Maurizio, Pezzullo, Luciano, Chiofalo, Maria Grazia, Zaccaroni, Alberto, Pino, Antonella, Carcoforo, Paolo, D’Amore, Annamaria, De Crea, Carmela, Avenia, Nicola, Raffaelli, Marco, Conzo, Giovanni, Del Rio, Paolo, Docimo, Giovanni, Testini, Mario, and Lombardi, Celestino Pio

Published
2020
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72. Bariatric surgery and the COVID-19 pandemic: SICOB recommendations on how to perform surgery during the outbreak and when to resume the activities in phase 2 of lockdown

Author

Navarra, Giuseppe, Komaei, Iman, Currò, Giuseppe, Angrisani, Luigi, Bellini, Rosario, Cerbone, Maria Rosaria, Di Lorenzo, Nicola, De Luca, Maurizio, Foletto, Mirto, Gentileschi, Paolo, Musella, Mario, Nannipieri, Monica, Piazza, Luigi, Olmi, Stefano, Pilone, Vincenzo, Raffaelli, Marco, Sarro, Giuliano, Vitiello, Antonio, Zappa, Marco Antonio, and Foschi, Diego

Published
2020
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76. Clinical outcomes after surgery for primary aldosteronism: Evaluation of the PASO-investigators’ consensus criteria within a worldwide cohort of patients

Author

Zarnegar, Rasa, Drake, Frederick T., Duh, Quan Y., Talutis, Stephanie D., McAneny, David B., McManus, Catherine, Lee, James A., Grant, Scott B., Grogan, Raymon H., Romero Arenas, Minerva A., Perrier, Nancy D., Peipert, Benjamin J., Mongelli, Michael N., Castelino, Tanya, Mitmaker, Elliot J., Parente, David N., Pasternak, Jesse D., Engelsman, Anton F., Sywak, Mark, D’Amato, Gerardo, Raffaelli, Marco, Schuermans, Valerie, Bouvy, Nicole D., Eker, Hasan H., Bonjer, H. Jaap, Vaarzon Morel, Nina M., Nieveen van Dijkum, Els J.M., Metman, Madelon J.H., Kruijff, Schelto, Vorselaars, Wessel M.C.M., van Beek, Dirk-Jan, Postma, Emily L., Spiering, Wilko, Borel Rinkes, Inne H.M., Valk, Gerlof D., and Vriens, Menno R.

Published
2019
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77. Feasibility of Roux-en-Y Gastric Bypass with the novel robotic platform HUGOTM RAS

Author

Raffaelli, Marco, Voloudakis, Nikolao, Pennestri', Francesco, Gallucci, Pierpaolo, Modesti, Cristina, Salvi, Giulia, Greco, Francesco, Ciccoritti, Luigi, Raffaelli, Marco (ORCID:0000-0002-1259-2491), Pennestri, Francesco (ORCID:0000-0003-0865-700X), Modesti, Cristina (ORCID:0000-0002-5858-3136), Raffaelli, Marco, Voloudakis, Nikolao, Pennestri', Francesco, Gallucci, Pierpaolo, Modesti, Cristina, Salvi, Giulia, Greco, Francesco, Ciccoritti, Luigi, Raffaelli, Marco (ORCID:0000-0002-1259-2491), Pennestri, Francesco (ORCID:0000-0003-0865-700X), and Modesti, Cristina (ORCID:0000-0002-5858-3136)

Abstract

Introduction: Robotic assisted surgery is a rapidly developing field of minimally invasive bariatric surgery in the last 20 years. Its wide diffusion has led to the development and standardization of robotic assisted approaches for bariatric operations. In this study, we present the first four Roux-en-Y Gastric Bypass (RYGB) operations performed with the new Hugo (TM) RAS system (Medtronic, Minneapolis, MN, USA).Methods: In January and February 2023, 4 consecutive patients scheduled for minimal invasive Roux-en-Y-Bypass were selected and underwent the procedure robotic-assisted with the new platform. No exclusion criteria were applied.Results: Four patients, two females and two males, underwent RYGB with a median BMI of 40 Kg/m(2) (range: 36-46) and diabetes mellitus in two cases. The median docking time was 8 min (range: 7-8.5) and the median console time was 127.5 min (range: 95-150). A description of the operating theatre, robotic arms and docking setup is provided. Procedures were performed without intraoperative complications and no conversion to laparoscopy or open surgery was noted. No additional ports were needed to be placed. System's function and docking were uneventful. No early post-operative complications were observed.Conclusions: Based on our initial experience, RYGB with the Hugo (TM) RAS system is feasible. This study provides the configurations necessary to perform RYGB with the Hugo (TM) RAS system as well as general information and insights from our preliminary experience.

Published
2023

78. Is There Any Reliable Predictor of Functional Recovery Following Vocal Fold Paralysis?

Author

Revelli, Luca, Gallucci, Pierpaolo, Marchese, Maria Raffaella, Voloudakis, Nikolao, Di Lorenzo, Sofia, Montuori, Claudio, D'Alatri, Lucia, Pennestri', Francesco, De Crea, Carmela, Raffaelli, Marco, Revelli, Luca (ORCID:0000-0003-1907-773X), Marchese, Maria Raffaella (ORCID:0000-0003-0751-0882), D'Alatri, Lucia (ORCID:0000-0003-3104-958X), Pennestri, Francesco (ORCID:0000-0003-0865-700X), De Crea, Carmela (ORCID:0000-0002-7303-9657), Raffaelli, Marco (ORCID:0000-0002-1259-2491), Revelli, Luca, Gallucci, Pierpaolo, Marchese, Maria Raffaella, Voloudakis, Nikolao, Di Lorenzo, Sofia, Montuori, Claudio, D'Alatri, Lucia, Pennestri', Francesco, De Crea, Carmela, Raffaelli, Marco, Revelli, Luca (ORCID:0000-0003-1907-773X), Marchese, Maria Raffaella (ORCID:0000-0003-0751-0882), D'Alatri, Lucia (ORCID:0000-0003-3104-958X), Pennestri, Francesco (ORCID:0000-0003-0865-700X), De Crea, Carmela (ORCID:0000-0002-7303-9657), and Raffaelli, Marco (ORCID:0000-0002-1259-2491)

Abstract

Background Predicting definitive outcomes of post-thyroidectomy vocal fold paralysis (VFP) is challenging. We aimed to identify reliable predictors based on intraoperative neuromonitoring (IONM) and flexible fiberoptic laryngostroboscopy (FFL) findings. Methods Among 1172 thyroid operations performed from April to December 2021, all patients who exhibited vocal fold paralysis (VFP) at post-operative laryngoscopy were included. IONM data, including type of loss of signal (LOS), were collected. Patients underwent FFL, with arytenoid motility assessment, at 15, 45 and 120 days post-operatively. Patients were divided into two groups: those who recovered vocal fold motility (VFM) by the 120th post-operative day (recovery group) and those who did not (non-recovery group). Results Fifty-nine VFP cases (5.0% of total patients) met the inclusion criteria. Eight patients were lost at follow-up and were excluded. Overall, 9 patients were included in the non-recovery group (0.8% of total patients) and 42 in the recovery group. Among various predictive factors, only arytenoid fixation (AF) at the 15th post-operative day and Type I LOS were significant predictors for no VFM recovery (p = 0.007, RR = 9.739, CI:1.3-72.3 and p = 0.001, RR = 9.25, CI:2.2-39.3 for AF and Type I injury, respectively). The combination of type of LOS and arytenoid motility at the 15th post-op day yielded satisfactory predictive values for the progression of transient VFP to permanent. Conclusions Arytenoid motility at the 15th post-op day and type II LOS are associated with recovery of VFM. Type of LOS and FFL could be included in the follow-up protocols of patients with VFP to reliably predict clinical outcomes.

Published
2023

79. p53 expression in cytology samples may represent a marker of early-stage cancer

Author

Policardo, Federica, Tralongo, Pietro, Arciuolo, Damiano, Fiorentino, Vincenzo, Cardasciani, Lina, Pierconti, Francesco, Carlino, Angela, Curatolo, Mariangela, Pontecorvi, Alfredo, Fadda, Guido, De Crea, Carmela, Lombardi, Celestino Pio, Raffaelli, Marco, Larocca, Luigi Maria, Pantanowitz, Liron, Rossi, Esther, Pierconti, Francesco (ORCID:0000-0003-0951-4131), Pontecorvi, Alfredo (ORCID:0000-0003-0570-6865), Fadda, Guido (ORCID:0000-0003-2013-7293), De Crea, Carmela (ORCID:0000-0002-7303-9657), Lombardi, Celestino Pio (ORCID:0000-0001-8910-6693), Raffaelli, Marco (ORCID:0000-0002-1259-2491), Larocca, Luigi Maria (ORCID:0000-0003-1739-4758), Rossi, Esther (ORCID:0000-0003-3819-4229), Policardo, Federica, Tralongo, Pietro, Arciuolo, Damiano, Fiorentino, Vincenzo, Cardasciani, Lina, Pierconti, Francesco, Carlino, Angela, Curatolo, Mariangela, Pontecorvi, Alfredo, Fadda, Guido, De Crea, Carmela, Lombardi, Celestino Pio, Raffaelli, Marco, Larocca, Luigi Maria, Pantanowitz, Liron, Rossi, Esther, Pierconti, Francesco (ORCID:0000-0003-0951-4131), Pontecorvi, Alfredo (ORCID:0000-0003-0570-6865), Fadda, Guido (ORCID:0000-0003-2013-7293), De Crea, Carmela (ORCID:0000-0002-7303-9657), Lombardi, Celestino Pio (ORCID:0000-0001-8910-6693), Raffaelli, Marco (ORCID:0000-0002-1259-2491), Larocca, Luigi Maria (ORCID:0000-0003-1739-4758), and Rossi, Esther (ORCID:0000-0003-3819-4229)

Abstract

BackgroundTP53 gene plays a major role in the negative control of cell proliferation and in the regulation of signaling cascades. TP53 mutation may have a relevant role in the malignant transformation of thyroid cells as well as thyroid tumor progression. TP53 mutation has been detected only in few well differentiated thyroid carcinomas and is absent in benign conditions. MethodsA total of 162 prospective thyroid cytology and corresponding histological samples diagnosed from atypia of indeterminate significance (AUS) to malignant, were studied via immunocytochemistry for p53. Hence, 50 benign lesions (B) were used as negative control. Molecular analysis for p53 only was performed. ResultsThe cytology resulted in 50 B, 48 AUS, 40 follicular neoplasms (FNs), 23 suspicious for malignancy (SFM), and 1 malignant (M) case. The authors reported 102 negative and 60 positive p53 cases. The 60 positive cases included 27 cases with weak and/or focal cytoplasmic positivity (+1) and 33 with cases moderate (2+) to strong (3+) cytoplasmic and/or nuclear expression. Overall, 71 cases had histology (2 B, 11 AUS, 37 FN, 20 SFM, and 1 M) including 61.7% benign and 38.2% malignant diagnoses. Only 16 of 71 (5 FN, 10 SFM, and 1 M) were p53-positive. Furthermore, 100% AUS and 86.5% FN cases were p53-negative, none of which had malignant histology. All p53-positive cases were associated with a larger nodule size, tall-cell variant subtype, multifocality, extra thyroidal infiltration, and nodal metastases. Noninvasive follicular thyroid neoplasm with papillary like nuclear features were negative for p53. Few discrepancies in p53 intensity were observed on histology; there were no differences with the molecular testing. Conclusionsp53 might be useful in discriminating thyroid follicular lesions. p53 is likely to be a useful diagnostic marker in recognizing indeterminate lesions that are well-differentiated thyroid cancers.

Published
2023

80. Multifocality in thyroid lobectomy and completion thyroidectomy – a single tertiary center retrospective study

Author

Policardo, Federica, primary, Bruno, Carmine, additional, Tralongo, Pietro, additional, Vegni, Federica, additional, Feraco, Angela, additional, Zhang, Qianqian, additional, Padial-Urtueta, Belen, additional, Carlino, Angela, additional, Pontecorvi, Alfredo, additional, Fadda, Guido, additional, Raffaelli, Marco, additional, Larocca, Luigi Maria, additional, Pantanowitz, Liron, additional, and Rossi, Esther Diana, additional

Published
2024
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82. Comparison between DaVinci® and Hugo™-RAS Roux-en-Y Gastric Bypass in bariatric surgery.

Author

Pennestrì, Francesco, Marincola, Giuseppe, Procopio, Priscilla Francesca, Gallucci, Pierpaolo, Salvi, Giulia, Ciccoritti, Luigi, Greco, Francesco, and Raffaelli, Marco

Abstract

The application of a robotic platform in the bariatric surgical field is intended to enhance the already established advantages of minimally invasive surgery in terms of both technical and clinical outcomes. These advantages are especially relevant for technically challenging multiquadrant operations such as Roux-en-Y Gastric Bypass (RYGB). Consequently, robotic-assisted surgery has emerged as a possible application for bariatric surgeries. The study attempts to assess feasibility and safety of the Hugo™-Robotic-Assisted Surgery System (Hugo™-RAS) platform compared to the DaVinci® Surgical System (DaVinci®-SS) with a focus on complication rates and operative times. We retrospectively reviewed bariatric procedures performed from January 2013 until December 2023. We included all robotic RYGBs performed using Hugo™-RAS and DaVinci®-SS platforms. The study utilized Propensity Score Matching (PSM) analysis to address bias in selection, matching patients based on age, gender, body mass index, comorbidities and past abdominal operations. One hundred thirty-five patients were identified: 90 DaVinci®-SS and 45 Hugo™-RAS procedures. After PSM, each group consisted of 45 patients. There was no discernible disparity observed in relation to early (≤ 30 days) postoperative complications rate (p = 1), mean operative time (for docking time, console time and total operative time: p = 0.176, p = 0.678, p = 0.229, respectively) and postoperative hospital stay (p = 0.052) between DaVinci®-RSS and Hugo™-RAS procedures. Our results suggest that application of both Hugo™-RAS and DaVinci®-SS robotic platforms to RYGB is related to comparable safety profiles. Although DaVinci®-SS remains the most widely adopted platform in clinical practice, this study underscores the potential role of the Hugo™-RAS to provide effective solutions in robotic bariatric procedures. [ABSTRACT FROM AUTHOR]

Published
2024
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83. The European Thyroid Imaging and Reporting Data System as a Remedy for the Overdiagnosis and Overtreatment of Thyroid Cancer: Results from the EUROCRINE Surgical Registry.

Author

Hellmann, Andrzej Rafał, Wiśniewski, Piotr, Śledziński, Maciej, Raffaelli, Marco, Kobiela, Jarosław, and Barczyński, Marcin

Subjects
MEDICAL information storage & retrieval systems, PREDICTIVE tests, LYMPH nodes, THYROID gland tumors, OVERDIAGNOSIS, RECEIVER operating characteristic curves, REPORTING of diseases, DESCRIPTIVE statistics, OVERTREATMENT, MEDICAL radiology, NEEDLE biopsy, DATA analysis software, SENSITIVITY & specificity (Statistics)
Abstract

Simple Summary: The European Thyroid Imaging and Reporting Data System (EU-TIRADS) aids clinicians in determining the necessity of fine-needle aspiration biopsy (FNAB) for thyroid nodules suspected of malignancy. This study evaluated the effectiveness of EU-TIRADS criteria in real-world surgical settings. Results indicated that the EU-TIRADS demonstrates reliable diagnostic accuracy in identifying thyroid cancer, facilitating improved clinical decision-making regarding patient management. Enhanced adherence to EU-TIRADS guidelines can mitigate the risk of an overdiagnosis and overtreatment, particularly for low-risk thyroid cancer cases, thereby optimizing patient care. Background: The European Thyroid Imaging and Reporting Data System (EU-TIRADS) aims to reduce the overdiagnosis of thyroid cancer (TC) by guiding the selection of nodules for fine-needle aspiration biopsy (FNAB). This study sought to validate EU-TIRADS nodule selection criteria using data from EUROCRINE, an extensive international endocrine surgery registry. Method: We reviewed indications for FNAB among patients with TC compared to those with benign disease who underwent surgery between March 2020 and March 2022, considering preoperative EU-TIRADS scores and dominant nodule size (FNAB is recommended in Category 5 (˃10 mm or ˂10 mm with suspicious lymph nodes), 4 (˃15 mm), and 3 (˃20 mm)). Patients were categorized into three risk groups: minimal risk (patients with papillary microcarcinoma), high risk (patients with pT3b stage or higher, pN1b, or pM1), and low–moderate risk (all other patients). We conducted a Receiver Operating Characteristic (ROC) analysis to assess the diagnostic accuracy of the EU-TIRADS. Results: We analyzed 32,008 operations. Approximately 68% of the surgical records included EU-TIRADS classifications. The EU-TIRADS exhibited diagnostic accuracy across high-volume sites, with a median ROC Area Under the ROC Curve (AUC) of 0.752, indicating its effectiveness in identifying malignancy. Among the cases, 7907 patients had TC. Notably, 55% of patients with TC underwent FNAB despite not initially meeting the EU-TIRADS criteria. These patients were distributed across the minimal- (58%), low–moderate- (36%), and high-risk (5.8%) categories. Of the patients with TC recommended for FNAB, 78% were deemed low–moderate risk, 21% high risk, and only 0.7% minimal risk. Conclusion: The EU-TIRADS offers effective preoperative malignancy risk stratification. Promoting the proper use of the EU-TIRADS in clinical practice is essential to mitigate the overdiagnosis and overtreatment of low-risk TC. [ABSTRACT FROM AUTHOR]

Published
2024
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84. Contributors

Author

Abraham, Devaprabu, primary, Abraham, Nikita R., additional, Agarwal, Amit, additional, Ahadi, Mahsa S., additional, Alameer, Ehab, additional, Alobuia, Wilson, additional, Alon, Eran E., additional, Angkoon, Anuwong, additional, Al-Qurayshi, Zaid, additional, Angell, Trevor E., additional, Angelos, Peter, additional, Baek, Jung Hwan, additional, Baloch, Zubair W., additional, Barczyński, Marcin, additional, Bauer, Andrew J., additional, Bellantone, Rocco, additional, Berdelou, Amandine, additional, Bergenfeltz, Anders, additional, Bernet, Victor J., additional, Bible, Keith C., additional, Bilezikian, John Paul, additional, Bonilla-Velez, Juliana, additional, Boucai, Laura, additional, Brent, Gregory A., additional, Breuskin, Ingrid, additional, Brierley, James Duncan, additional, Brisebois, Simon, additional, Brooks, Jennifer, additional, Brumund, Kevin T., additional, Bura, Mijenko, additional, Alvarez, Jean Gabriel Bustamante, additional, Carneiro-Pla, Denise, additional, Cernea, Claudio R., additional, Chang, Rita Yuk-kwan, additional, Chen, Amy, additional, Chiang, Feng-Yu, additional, Chintakuntlawar, Ashish V., additional, Cho, Nancy L., additional, Chung, Woong Youn, additional, Cibas, Edmund S., additional, Dacey, Carolyn, additional, Davies, Louise, additional, De Crea, Carmela, additional, Delbridge, Leigh, additional, Diercks, Gillian, additional, Doherty, Gerard M., additional, Dralle, Henning, additional, Duh, Quan-Yang, additional, Dunlap, Quinn Alexander, additional, Durante, Cosmio, additional, Eltelety, Ahmad Mohamed, additional, Evans, Douglas B., additional, Fadda, Guido, additional, Faquin, William C., additional, Felger, Erin, additional, Ferris, Robert L., additional, Filetti, Sebastiano, additional, Freeman, Jeremy L., additional, Fundakowski, Christopher, additional, Ganly, Ian, additional, Gigliotti, Benjamin Joseph, additional, Gill, Anthony J., additional, Giordano, Thomas J., additional, Giuliani, Meredith E., additional, Gooi, Zhen, additional, Gopal, Raj K., additional, Guerlain, Joanne, additional, Hadoux, Julien, additional, Hales, Nathan, additional, Hartl, Dana, additional, Haugen, Bryan R., additional, Haymart, Megan R., additional, Inabnet, William B., additional, Irish, Jonathan, additional, Iwata, Ayaka, additional, Kamani, Dipti, additional, Kandil, Emad, additional, Kaplan, Edwin L., additional, Kazahaya, Ken, additional, Kebebew, Electron, additional, Kim, Matthew I., additional, Kovatch, Kevin J., additional, Lang, Brian H.H., additional, Leboulleux, Sophie, additional, Leung, Angela M., additional, Levine, Robert A., additional, Liddy, Whitney, additional, LiVolsi, Virginia A., additional, Lombardi, Celestino Pio, additional, Lubitz, Carrie C., additional, Machens, Andreas, additional, Maghami, Ellie, additional, Mandel, Susan J., additional, Maniakas, Anastasios, additional, Mathisen, Douglas J., additional, Mathur, Aarti, additional, Merati, Albert, additional, Milas, Mira, additional, Miyauchi, Akira, additional, Monteiro, Eric, additional, Netterville, James L., additional, Nikiforov, Yuri E., additional, Orloff, Lisa A., additional, Pandian, T.K., additional, Parangi, Sareh, additional, Parikh, Sanjay, additional, Park, Auh Whan, additional, Pearce, Elizabeth N., additional, Pellitteri, Phillip K., additional, Pennestrì, Francesco, additional, Pradhan, Roma, additional, Prichard, Ruth, additional, Raffaelli, Marco, additional, Randolph, Gregory W., additional, Rastatter, Jeff, additional, Reid, Lisa M., additional, Richer, Sara L., additional, Richmon, Jeremy D., additional, Ringel, Matthew D., additional, Roman, Benjamin R., additional, Romanchishen, Anatoly F., additional, Ross, Douglas S., additional, Russell, Jonathon O., additional, Russell, Marika D., additional, Ryder, Mabel, additional, Sabra, Mona M., additional, Sachdeva, Uma M., additional, Sadow, Peter M., additional, Scharpf, Joseph, additional, Schlumberger, Martin, additional, Schneider, Rick, additional, Scott-Coombes, David, additional, Sewell, Andrew B., additional, Shah, Jatin, additional, Shah, Manisha H., additional, Shindo, Maisie, additional, Shonka, David, additional, Silverberg, Shonni Joy, additional, Sims, John Randall, additional, Sinclair, Catherine F., additional, Singer, Michael C., additional, Siperstein, Allan E., additional, Sipos, Jennifer A., additional, Slough, Cristian Martin, additional, Sosa, Julie A., additional, Soylu, Selen, additional, Stack, Brendan C., additional, Stathatos, Nikolaos, additional, Stechman, Michael James, additional, Stephen, Antonia E., additional, Steward, David L., additional, Suh, Hyun, additional, Sywak, Mark, additional, Tang, Alice, additional, Terris, David J., additional, Thompson, Geoffrey Bruce, additional, Tolley, Neil, additional, Tominaga, Yoshihiro, additional, Triponez, Frédéric, additional, Tsang, Richard W., additional, Tuttle, R. Michael, additional, Urken, Mark L., additional, Vabalayte, Kristina V., additional, Vahabzadeh-Hagh, Andrew M., additional, Volpi, Erivelto Martinho, additional, Wang, Tracy S., additional, Wu, Che-Wei, additional, Wirth, Lori J., additional, Witterick, Ian, additional, Wong, Richard J., additional, Woodson, Gayle E., additional, Wright, Cameron D., additional, Zafereo, Mark E., additional, and Zubiaur, Fermin M., additional

Published
2021
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87. Volume-Outcome Relationship in Endocrine Surgery

Author

Bellantone, Rocco, primary, Pennestrì, Francesco, additional, De Crea, Carmela, additional, Lombardi, Celestino Pio, additional, Testini, Mario, additional, De Toma, Giorgio, additional, and Raffaelli, Marco, additional

Published
2020
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92. Giotto : il restauro e gli studi sul "Frammento Vaticano", proveniente dall'antica basilica di San Pietro a Roma

Author

Frosinini, Cecilia, Romano, Serena, Felici, Alberto, Brogi, Francesca, Dimuccio, Alberto, Innocenti, Federica, Lalli, Carlo Galliano, Lanterna, Giancarlo, Cartechini, Laura, Miliani, Costanza, Rosi, Francesca, Moioli, Pietro, Seccaroni, Claudio, Coli, Massimo, Innocenti, Lorenzo, Giannino, Fabio, Papeschi, Paolo, Barucci, Marco, Dal Fovo, Alice, Fontana, Raffaella, Pampaloni, Enrico, Raffaelli, Marco, and Striova, Jana

Published
2018

94. Barbed vs. Conventional Sutures in Bariatric Surgery: Early and Late Outcomes

Author

Pennestrì, Francesco, primary, Sessa, Luca, additional, Prioli, Francesca, additional, Gallucci, Pierpaolo, additional, Salvi, Giulia, additional, Procopio, Priscilla Francesca, additional, Martullo, Annamaria, additional, Petrazzuolo, Eleonora, additional, Di Lorenzo, Sofia, additional, Ciccoritti, Luigi, additional, Giustacchini, Piero, additional, Greco, Francesco, additional, Revelli, Luca, additional, Marincola, Giuseppe, additional, Laurino, Antonio, additional, De Crea, Carmela, additional, and Raffaelli, Marco, additional

Published
2023
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96. List of Contributors

Author

Asare, Elliot A., primary, Bai, Harrison X., additional, Bancos, Irina, additional, Bauer, Andrew J., additional, Carmela, De Crea, additional, Chen, Yufei, additional, Delivanis, Danae, additional, Dralle, Henning, additional, Duh, Quan-Yang, additional, Fahey, Thomas J., additional, Fernandez Ranvier, Gustavo G., additional, Finnerty, Brendan M., additional, Fisher, Sarah B., additional, Francesco, Pennestrì, additional, Habra, Mouhammed Amir, additional, Hallman, Joan, additional, Halsey, Jordan N., additional, Hamidi, Oksana, additional, Inabnet, William B., additional, Ito, Yasuhiro, additional, Kebebew, Electron, additional, Krasnova, Svetlana L., additional, Kruijff, Schelto, additional, Laird, Amanda M., additional, Lee, James A., additional, Libutti, Steven K., additional, Lou, Irene, additional, Machens, Andreas, additional, Maggio, William W., additional, Marcadis, Andrea R., additional, Raffaelli, Marco, additional, Mazeh, Haggi, additional, McCartney-Anderson, Maureen, additional, Mekel, Michal, additional, Meknat, Aryan, additional, Miyauchi, Akira, additional, Nobecourt, Priscilla, additional, Patel, Tushar R., additional, Pearlstein, Sarah S., additional, Perrier, Nancy D., additional, Pio, Lombardi Celestino, additional, Rocco, Bellantone, additional, Schmid, Kurt Werner, additional, Shah, Meera, additional, Shaha, Ashok R., additional, Shargorodsky, Josef, additional, Sharma, Anu, additional, Shifrin, Alexander L., additional, Silva-Figueroa, Angelica M., additional, Sinclair, Tiffany J., additional, Stratakis, Constantine A., additional, Suzuki, Mari, additional, Trerotola, Scott O., additional, van der Plas, Willemijn Y., additional, Vogt, Liffert, additional, and Yalon, Tal, additional

Published
2020
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99. Surgical Technique in Reoperations

Author

Bellantone, Rocco, Traini, Emanuela, Raffaelli, Marco, Lombardi, Celestino P., Gasparri, Guido, editor, Palestini, Nicola, editor, Camandona, Michele, editor, and Corcione, Francesco

Published
2016
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