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2,615 results on '"Ramanathan, S"'

52. Analytical characterization of engineered nanostructures – Techniques and challenges.

Author

Ramanathan, S., Gopinath, S. C. B., Anbu, P., and Selvarajan, R. S.

Subjects
*NANOSTRUCTURES, *NANOSTRUCTURED materials, *NANOPARTICLES
Abstract

Numerous nanostructures with nanoscale dimensions smaller than 100 nm have been developed. These nanostructures, including those with promising uses, have novel physicochemical characteristics that affect the molecular and systemic levels of their physiological interactions. The need for analytical data relevant to manufactured nanomaterials is growing, necessitating the modification of current techniques and methodologies or the creation of new ones. The analytical sciences have faced a hurdle in recognizing nanoparticles as a novel class of analytes that include both chemical and physical information. It is also necessary to provide details on the physiochemical characteristics of nanoparticles and their changes. This article discusses primary available characterizing techniques to deal with engineered nanostructures for evaluating its quality and performances. The principle of each technique is included while indicating the strength and limitations in determining the physiochemical characteristics of engineered nanostructures. [ABSTRACT FROM AUTHOR]

Published
2024
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55. Reachability in Continuous Pushdown VASS

Author

Balasubramanian, A. R., Majumdar, Rupak, Thinniyam, Ramanathan S., Zetzsche, Georg, Balasubramanian, A. R., Majumdar, Rupak, Thinniyam, Ramanathan S., and Zetzsche, Georg

Abstract

Pushdown Vector Addition Systems with States (PVASS) consist of finitely many control states, a pushdown stack, and a set of counters that can be incremented and decremented, but not tested for zero. Whether the reachability problem is decidable for PVASS is a long-standing open problem. We consider continuous PVASS, which are PVASS with a continuous semantics. This means, the counter values are rational numbers and whenever a vector is added to the current counter values, this vector is first scaled with an arbitrarily chosen rational factor between zero and one. We show that reachability in continuous PVASS is NEXPTIME-complete. Our result is unusually robust: Reachability can be decided in NEXPTIME even if all numbers are specified in binary. On the other hand, NEXPTIME-hardness already holds for coverability, in fixed dimension, for bounded stack, and even if all numbers are specified in unary.

Published
2024
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56. The clinical relevance of MOG antibody testing in cerebrospinal fluid

Author

Reynolds, M, Tan, I, Nguyen, K, Merheb, V, Lee, FXZ, Trewin, BP, Lerch, M, Shah, S, Wolfe, N, Buzzard, K, Lechner-Scott, J, Fabis-Pedrini, M, Fok, A, John, N, Kneebone, C, Yiannikas, C, Brown, DA, Kermode, AG, Reddel, S, Dale, RC, Brilot, F, Ramanathan, S, Reynolds, M, Tan, I, Nguyen, K, Merheb, V, Lee, FXZ, Trewin, BP, Lerch, M, Shah, S, Wolfe, N, Buzzard, K, Lechner-Scott, J, Fabis-Pedrini, M, Fok, A, John, N, Kneebone, C, Yiannikas, C, Brown, DA, Kermode, AG, Reddel, S, Dale, RC, Brilot, F, and Ramanathan, S

Abstract

Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) is diagnosed by serum MOG-immunoglobulin G (MOG-IgG) in association with typical demyelination. 111/1127 patients with paired CSF/serum samples were seropositive for MOG-IgG. Only 7/1016 (0.7%) seronegative patients had CSF-restricted MOG-IgG. While 3/7 patients had longitudinally extensive transverse myelitis, four had a confirmed alternate diagnosis (three multiple sclerosis, one CNS vasculitis). In a national referral setting, CSF-restricted MOG-IgG had a low sensitivity (2.63%, 95%CI 0.55-7.50%) and low positive predictive value (1.97%, 95%CI 0.45-8.13%). We strongly recommend serum as the preferred diagnostic biospecimen, and urge caution in the interpretation of CSF-restricted MOG-IgG in patients without clinico-radiological features consistent with MOGAD.

Published
2024

57. Treatment of MOG antibody associated disorders: results of an international survey

Author

Whittam, D. H., Karthikeayan, V., Gibbons, E., Kneen, R., Chandratre, S., Ciccarelli, O., Hacohen, Y., de Seze, J., Deiva, K., Hintzen, R. Q., Wildemann, B., Jarius, S., Kleiter, I., Rostasy, K., Huppke, P., Hemmer, B., Paul, F., Aktas, O., Pröbstel, A. K., Arrambide, G., Tintore, M., Amato, M. P., Nosadini, M., Mancardi, M. M., Capobianco, M., Illes, Z., Siva, A., Altintas, A., Akman-Demir, G., Pandit, L., Apiwattankul, M., Hor, J. Y., Viswanathan, S., Qiu, W., Kim, H. J., Nakashima, I., Fujihara, K., Ramanathan, S., Dale, R. C., Boggild, M., Broadley, S., Lana-Peixoto, M. A., Sato, D. K., Tenembaum, S., Cabre, P., Wingerchuk, D. M., Weinshenker, B. G., Greenberg, B., Matiello, M., Klawiter, E. C., Bennett, J. L., Wallach, A. I., Kister, I., Banwell, B. L., Traboulsee, A., Pohl, D., Palace, J., Leite, M. I., Levy, M., Marignier, R., Solomon, T., Lim, M., Huda, S., and Jacob, A.

Published
2020
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62. Context-Bounded Analysis of Concurrent Programs (Invited Talk)

Author

Pascal Baumann and Moses Ganardi and Rupak Majumdar and Ramanathan S. Thinniyam and Georg Zetzsche, Baumann, Pascal, Ganardi, Moses, Majumdar, Rupak, Thinniyam, Ramanathan S., Zetzsche, Georg, Pascal Baumann and Moses Ganardi and Rupak Majumdar and Ramanathan S. Thinniyam and Georg Zetzsche, Baumann, Pascal, Ganardi, Moses, Majumdar, Rupak, Thinniyam, Ramanathan S., and Zetzsche, Georg

Abstract

Context-bounded analysis of concurrent programs is a technique to compute a sequence of under-approximations of all behaviors of the program. For a fixed bound k, a context bounded analysis considers only those runs in which a single process is interrupted at most k times. As k grows, we capture more and more behaviors of the program. Practically, context-bounding has been very effective as a bug-finding tool: many bugs can be found even with small bounds. Theoretically, context-bounded analysis is decidable for a large number of programming models for which verification problems are undecidable. In this paper, we survey some recent work in context-bounded analysis of multithreaded programs. In particular, we show a general decidability result. We study context-bounded reachability in a language-theoretic setup. We fix a class of languages (satisfying some mild conditions) from which each thread is chosen. We show context-bounded safety and termination verification problems are decidable iff emptiness is decidable for the underlying class of languages and context-bounded boundedness is decidable iff finiteness is decidable for the underlying class.

Published
2023
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63. Checking Refinement of Asynchronous Programs Against Context-Free Specifications

Author

Pascal Baumann and Moses Ganardi and Rupak Majumdar and Ramanathan S. Thinniyam and Georg Zetzsche, Baumann, Pascal, Ganardi, Moses, Majumdar, Rupak, Thinniyam, Ramanathan S., Zetzsche, Georg, Pascal Baumann and Moses Ganardi and Rupak Majumdar and Ramanathan S. Thinniyam and Georg Zetzsche, Baumann, Pascal, Ganardi, Moses, Majumdar, Rupak, Thinniyam, Ramanathan S., and Zetzsche, Georg

Abstract

In the language-theoretic approach to refinement verification, we check that the language of traces of an implementation all belong to the language of a specification. We consider the refinement verification problem for asynchronous programs against specifications given by a Dyck language. We show that this problem is EXPSPACE-complete - the same complexity as that of language emptiness and for refinement verification against a regular specification. Our algorithm uses several technical ingredients. First, we show that checking if the coverability language of a succinctly described vector addition system with states (VASS) is contained in a Dyck language is EXPSPACE-complete. Second, in the more technical part of the proof, we define an ordering on words and show a downward closure construction that allows replacing the (context-free) language of each task in an asynchronous program by a regular language. Unlike downward closure operations usually considered in infinite-state verification, our ordering is not a well-quasi-ordering, and we have to construct the regular language ab initio. Once the tasks can be replaced, we show a reduction to an appropriate VASS and use our first ingredient. In addition to the inherent theoretical interest, refinement verification with Dyck specifications captures common practical resource usage patterns based on reference counting, for which few algorithmic techniques were known.

Published
2023
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67. Observation of a uniform temperature dependence in the electrical resistance across the structural phase transition in thin film vanadium oxide ($VO_{2}$)

Author

Mani, R. G. and Ramanathan, S.

Subjects
Condensed Matter - Mesoscale and Nanoscale Physics, Condensed Matter - Materials Science
Abstract

An electrical study of thin $VO_{2}$ films in the vicinity of the structural phase transition at $68^{0}C$ shows (a) that the electrical resistance $R$ follows $log (R)$ $\propto$ $-T$ over the $T$-range, $20 < T < 80 ^{0}C$ covering both sides of the structural transition, and (b) a history dependent hysteresis loop in $R$ upon thermal cycling. These features are attributed here to transport through a granular network., Comment: 3 pages, 3 color figures

Published
2007
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74. Theranostic applications of nanoparticles in neurodegenerative disorders

Author

Ramanathan S, Archunan G, Sivakumar M, Tamil Selvan S, Fred AL, Kumar S, Gulyás B, and Padmanabhan P

Subjects
theranostics, neurological disease, nanoparticles, imaging., Medicine (General), R5-920
Abstract

Sahana Ramanathan,1 Govindaraju Archunan,2 Muthusamy Sivakumar,3 Subramanian Tamil Selvan,4 A Lenin Fred,5 Sundramurthy Kumar,1 Balázs Gulyás,1 Parasuraman Padmanabhan1 1Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore; 2Department of Animal Science, Centre for Pheromone Technology (CPT), Bharathidasan University, Tiruchirappalli, India; 3Nanoscience and Technology, Anna University – BIT Campus, Tiruchirappalli, India; 4Institute of Materials Research and Engineering, Singapore; 5Mar Ephraem College of Engineering and Technology, Kanyakumari, India Abstract: The preeminent treatments for neurodegenerative disease are often unavailable due to the poor accessibility of therapeutic drugs. Moreover, the blood–brain barrier (BBB) effectively blocks the transfer of cells, particles and large molecules, ie, drugs, across the brain. The most important challenge in the treatment of neurodegenerative diseases is the development of targeted drug delivery system. Theranostic strategies are known to combine therapeutic and diagnostic capabilities together. The aim of this review was to record the response to treatment and thereby improve drug safety. Nanotechnology offers a platform for designing and developing theranostic agents that can be used as an efficient nano-carrier system. This is achieved by the manipulation of some of the properties of nanoparticles (NPs), thereby enabling the attachment of suitable drugs onto their surface. The results provide revolutionary treatments by stimulation and thus interaction with targeted sites to promote physiological response with minimum side effects. This review is a brief discussion of the administration of drugs across the brain and the advantages of using NPs as an effective theranostic platform in the treatment of Alzheimer’s, Parkinson’s, epilepsy and Huntington’s disease. Keywords: theranostics, neurological disease, nanoparticles, imaging

Published
2018

88. Existential Definability over the Subword Ordering

Author

Pascal Baumann and Moses Ganardi and Ramanathan S. Thinniyam and Georg Zetzsche, Baumann, Pascal, Ganardi, Moses, Thinniyam, Ramanathan S., Zetzsche, Georg, Pascal Baumann and Moses Ganardi and Ramanathan S. Thinniyam and Georg Zetzsche, Baumann, Pascal, Ganardi, Moses, Thinniyam, Ramanathan S., and Zetzsche, Georg

Published
2022
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89. Worldwide Disparities in Recovery of Cardiac Testing 1 Year Into COVID-19

Author

Einstein, A, Hirschfeld, C, Williams, M, Vitola, J, Better, N, Villines, T, Cerci, R, Shaw, L, Choi, A, Dorbala, S, Karthikeyan, G, Lu, B, Sinitsyn, V, Ansheles, A, Kudo, T, Bucciarelli-Ducci, C, Norgaard, B, Maurovich-Horvat, P, Campisi, R, Milan, E, Louw, L, Allam, A, Bhatia, M, Sewanan, L, Malkovskiy, E, Cohen, Y, Randazzo, M, Narula, J, Morozova, O, Pascual, T, Pynda, Y, Dondi, M, Paez, D, Hinterleitner, G, Lu, Y, Xu, Z, Erinne, I, Shetty, M, Lopez-Mattei, J, Parwani, P, Goda, A, Shirka, E, Bouyoucef, S, Chelghoum, L, Mansouri, F, Medjahedi, A, Naili, Q, Ridouh, M, Alasia, D, Alberghina, L, Aramayo, N, Buchara, D, Busso, F, Bustos Rivadero, J, Camilletti, J, Campanelli, H, Castro, R, Daicz, M, del Riego, H, Dragonetti, L, Echazarreta, D, Erriest, J, Faccio, F, Facello, A, Gallegos, H, Geronazzo, R, Glait, H, Hasbani, V, Jager, V, Lewkowicz, J, Lotti, J, Maciel, N, Masoli, O, Mastrovito, E, Medus, M, Merani, M, Molteni, S, Montecinos, M, Parisi, G, Sueldo, C, Perez de Arenaza, D, Quintana, L, Radzinschi, A, Redruello, M, Rodriguez, M, Rojas, H, Acuna, A, Schere, D, Traverso, S, Vazquez, G, Zeffiro, S, Sakanyan, M, Beuzeville, S, Boktor, R, Crowley, M, Downie, D, Dwivedi, G, Elison, B, Farouque, O, Jasper, K, Joshi, S, Lee, J, Lee, K, Lui, E, Mcconachie, P, Meaker, J, Nandurkar, D, Neill, J, O'Rourke, E, O'Sullivan, P, Pandos, G, Premaratne, M, Prior, D, Rutherford, N, Saunders, C, Taubman, K, Tauro, A, Taylor, A, Theuerle, J, Thomas, P, Tow, J, Upton, A, Vamadevan, S, Wayne, V, Wegner, E, Wong, D, Younger, J, Beitzke, D, Feuchtner, G, Sommer, O, Weiss, K, Maroz-Vadalazhskaya, N, Tserakhau, U, Homans, F, Van De Heyning, C, Araujo, R, Soldat-Stankovic, V, Stankovic, S, Almeida, A, Anselmi, C, Azevedo, G, Bittencourt, M, Pianta, D, Cabeda, E, Carreira, L, Coelho, I, de Amorim Fernandes, F, de Lorenzo, A, Delgado, R, Erthal, F, Fernandes, F, Fernandes, J, Ferreira de Souza, T, Foppa, M, Matos Alves, W, Gontijo, C, Gottlieb, I, Grossman, G, Albernaz Siqueira, M, Nomura, C, Koga, K, Lima, R, Lopes, R, Marcal Filho, H, Masiero, P, Mastrocola, L, Menezes de Siqueira, M, Mesquita, C, Naves, D, Penna, F, Pinto, I, Rocha, T, Rocha, J, Rodrigues, A, Salioni, L, Sanches, A, Santos, M, Da Silva, L, Schvartzman, P, Matushita, C, Senra, T, Silva, M, Soares, C, Spiro, B, Suaide Silva, C, Torres, R, Monte, G, Vilela, A, Villa, A, Voss, T, Waltrick, R, Zapparoli, M, Naseer, H, Garcheva-Tsacheva, M, Ouattara, T, Thou, S, Varoeun, S, Abikhzer, G, Beanlands, R, Chetrit, M, Dabreo, D, Dennie, C, Friedrich, M, Hafez, M, Hanneman, K, Miller, R, Oikonomou, A, Roifman, I, Small, G, Tandon, V, Trivedi, A, White, J, Zukotynski, K, Alay, R, Concha, C, Massardo, T, Abad, P, Anzola, K, Arturo, H, Benitez, L, Cadena, A, Zamudio, C, Calderon, A, Gutierrez Villamil, C, Jaimes, C, Londono, J, Lopez, N, Merlano-Gaitan, S, Murgieitio-Cabrera, R, Valencia, M, Vergel, D, Santamaria, A, Solis, F, Batinic, T, Franceschi, M, Paar, M, Prpic, M, Felipe Batista, C, Cabrera, L, Peix, A, Pena, Y, Rochela Vazquez, L, Ntalas, I, Kaminek, M, Kincl, V, Lang, O, Abdulla, J, Bottcher, M, Busk, M, Geisler, U, Gormsen, L, Hansson, N, Hess, S, Hove, J, Jensen, L, Jensen, M, Kragholm, K, Ovrehus, K, Rasmussen, J, Ronnow Sand, N, Sondergaard, H, Zaremba, T, Speckter, H, Amores, N, Velez, M, Alrahman, T, Elsamad, S, Abdelfattah, A, Elkaffas, S, Hassan, M, Hussein, E, Ibrahim, A, Kandeel, A, Ali, M, Shaaban, M, Flores, C, Gomez Leiva, V, Liiver, A, Larikka, M, Uusitalo, V, Agostini, D, Berger, C, Dietz, M, Hyafil, F, Ohana, M, Prigent, K, Regaieg, H, Sarda-Mantel, L, H-Ici, D, Ayetey, H, Angelidis, G, Fragkaki, C, Fragkiadaki, C, Georgoulias, P, Koutelou, M, Kyrozi, E, Lama, N, Prassopoulos, V, Spartalis, M, Zaglavara, T, Gonzalez, C, Gutierrez, G, Maldonado, A, Martinez, Y, Kovacs, A, Szilveszter, B, Banthia, N, Bhat, V, Choudhury, P, Chowdekar, V, Christopher, J, Garg, T, Goyal, N, Gupta, R, Gupta, A, Hephzibah, J, Jain, S, Krupa, J, Kumar, P, Kumar, S, Lalchandani, A, Mishra, A, Mishra, V, Mohan, P, Ozair, A, Pandey, S, Parameswaran, R, Patel, C, Patel, T, Patel, S, Vimala, L, Kumar Sarangi, D, Sengupta, S, Sethi, A, Sharma, A, Sharma, P, Shrigiriwar, A, Singh, S, Singh, H, Sood, A, Verma, A, Vyas, A, Soeriadi, E, Bun, E, Hutomo, F, Syawaluddin, H, Yudistiro, R, Albadr, A, Assadi, M, Emami, F, Emami-Ardekani, A, Farzanehfar, S, Jafari, R, Manafi-Farid, R, Tajik, M, Arnson, Y, Fuchs, S, Goldkorn, R, Kennedy, J, Leitman, M, Shalev, A, Acampa, W, Albano, D, Alongi, P, Arnone, G, Assante, R, Baritussio, A, Bauckneht, M, Bianco, F, Bonfiglioli, R, Bovenzi, F, Bruno, I, Bruno, A, Busnardo, E, Califaretti, E, Casoni, R, Censullo, V, Chierichetti, F, Chiocchi, M, Cittanti, C, Clemente, A, Cuocolo, A, De Rimini, M, De Vincentis, G, Della Tommasina, V, Dellegrottaglie, S, Erba, P, Evangelista, L, Faggi, L, Faragasso, E, Florimonte, L, Frantellizzi, V, Gatti, M, Gaudiano, A, Gelardi, F, Gerali, A, Gimelli, A, Guglielmo, M, Leccisotti, L, Liga, R, Liguori, C, Longo, G, Maffione, M, Marcassa, C, Matassa, G, Mele, D, Mircoli, L, Paccagnella, A, Pacella, S, Padovano, F, Pellegrini, D, Pergola, V, Pugliese, L, Quartuccio, N, Rampin, L, Ricci, F, Rubini, G, Russo, V, Sambuceti, G, Scatteia, A, Sciagra, R, Spidalieri, G, Stefanelli, A, Tedeschi, C, Ventroni, G, Baugh, D, Madu, E, Aikawa, T, Asano, H, Fujimoto, S, Fujise, K, Fukushima, Y, Fukuyama, K, Ichikawa, Y, Ideguchi, R, Iguchi, N, Imai, M, Ishimura, H, Isobe, S, Ito, K, Izawa, Y, Kadokami, T, Kasai, T, Kato, T, Kawamoto, T, Kiryu, S, Kumita, S, Manabe, O, Maruno, H, Matsumoto, N, Miyagawa, M, Moroi, M, Nagamachi, S, Nakajima, K, Nakazato, R, Nanasato, M, Naya, M, Norikane, T, Ohta, Y, Otomi, Y, Otsuka, H, Oyama-Manabe, N, Saito, M, Sarai, M, Sato, J, Sato, D, Shiraishi, S, Takanami, K, Takehana, K, Taniguchi, Y, Teragawa, H, Tomizawa, N, Umeji, K, Wakabayashi, Y, Yamada, S, Yamazaki, S, Yoneyama, T, Rawashdeh, M, Dautov, T, Makhdomi, K, Abass, M, Garashi, M, Siraj, Q, Kalnina, M, Haidar, M, Komiagiene, R, Kviecinskiene, G, Vajauskas, D, Karim, N, Doucoure, M, Reichmuth, L, Samuel, A, Dieng, M, Naojee, A, Hernandez, E, Alducin Tellez, C, Alexanderson-Rosas, E, Barragan, E, Cabada, M, Calderon, D, Carvajal-Juarez, I, Esparza, J, Gama-Moreno, M, Quinto, V, Gonzalez, N, Herrera-Zarza, M, Meave, A, Medina Verdugo, J, Melendez, G, Morales Murguia, R, Navarro Quiroz, C, Ornelas, M, Preciado-Anaya, A, Preciado-Gutierrez, O, Puente, A, Salazar, A, Rosales Uvera, S, Rosales-Uvera, S, Serna Macias, J, Sierra-Galan, L, Tirado Alderete, J, Vallejo, E, Faraggi, M, Sereegotov, E, Ben Rais, N, Alaoui, N, Kyiphyu, T, Oo, S, Win, S, Zar, H, Ghimire, R, Neupane, M, Glaudemans, A, Slart, R, Verschure, D, Allen, B, Edmond, J, Mckenzie, C, Tie, S, Van Pelt, N, Worthington, K, Young, C, Soli, I, Kana, S, Onubogu, U, Sani, M, Braten, A, Jorgensen, A, Vassbotn, H, Al Dhuhli, H, Jawa, Z, Tag, N, Fatima, S, Imran, M, Younis, M, Saadullah, M, Malo, Y, Lenturut-Katal, D, Castillo, M, Ortellado, J, Akhter, A, Cader, F, Hussain, R, Khan, S, Mandal, T, Nasreen, F, An, Y, Cao, D, Gong, L, Hou, Y, Jia, C, Li, T, Li, C, Liu, H, Liu, W, Liu, J, Ng, M, Shi, H, Tang, C, Wang, X, Wang, Z, Wang, Y, Wu, J, Yi, Y, Yuan, L, Zhang, T, Zhang, L, Chavez, E, Cruz, C, Llontop, C, Morales, R, Abrihan, P, Bustos-Barroso, A, Duldulao-Ogbac, M, Eduarte, C, Obaldo, J, Quinon, A, San Juan, B, San Juan, C, Sauler-Gomez, M, Uy, M, Kostkiewicz, M, Kunikowska, J, Teresinska, A, Urbanik, T, Bettencourt, N, Fontes-Carvalho, R, Gavina, C, Goncalves, L, Macedo, F, Moreno, N, Sousa, C, Timoteo, A, Vidigal, M, Al Heidous, M, Ramanathan, S, Arnous, S, Aytani, S, Byrne, A, Gleeson, T, Kerins, D, O'Brien, J, Bang, J, Bom, H, Cheon, M, Cheon, G, Cho, S, Hong, C, Jeong, Y, Kang, W, Kang, Y, Kim, J, Oh, S, So, Y, Song, H, Won, K, Yoo, S, Mitevska, I, Vavlukis, M, Salobir, B, Stalc, M, Benedek, T, Pop, M, Stan, C, Dariy, O, Gagarina, N, Itskovich, I, Karalkin, A, Kokov, A, Marina, G, Migunova, E, Pospelov, V, Ryzhkova, D, Sayfullina, G, Sergienko, V, Shurupova, I, Vakhromeeva, M, Valiullina, N, Zavadovsky, K, Zhuravlev, K, Abazid, R, Al Garni, T, Alasnag, M, Aljizeeri, A, Amer, H, Amro, A, Hamdy, H, Smettei, O, Saranovic, D, Vlajkovic, M, Keng, F, See, J, Berecova, Z, Mistinova, J, Evbuomwan, O, Govender, N, Hack, J, Hadebe, B, Hlongwa, K, Kaplan, M, Lakhi, H, Milos, K, Modiselle, M, More, S, Muambadzi, N, Scholtz, L, Barreiro-Perez, M, Blanco, I, Broncano, J, Camarero, A, Casans-Tormo, I, De Haro, J, Flotats, A, Garcia, E, Mendiguchia, C, Jimenez-Heffernan, A, Leta, R, Diaz, J, Vega, L, Manovel-Sanchez, A, Monzonis, A, Patrut, B, Pubul, V, Perez, R, Zeidan, N, Nanayakkara, D, Suliman, A, Engblom, H, Murtadha, M, Ostenfeld, E, Simonsson, M, Alkadhi, H, Buechel, R, Burger, P, Grani, C, Kamani, C, Kawel-Bohm, N, Klaeser, B, Manka, R, Prior, J, Kaewchur, T, Khiewvan, B, Kositwattanarerk, A, Namwongprom, S, Thientunyakit, T, Sayman, H, Yuksel, M, Sebikali, M, Okello, E, Korol, P, Noverko, I, Satyr, M, Ahmad, T, Alfakih, K, Andrade, I, Buckingham, S, Bularga, A, Carpenter, J, Cole, G, Cusack, D, David, S, Davis, P, Fairbairn, T, Ghosh, A, Ramkumar, P, Hamilton, M, Haque, F, Hudson, B, Johnstone, A, Karthikeyan, V, Kay, M, Khan, M, Kitt, J, Low, C, Mcalindon, E, Mccreavy, D, Morrissey, B, Motwani, M, Na, D, Nicol, E, Patel, D, Rodrigues, J, Rofe, C, Schofield, R, Semple, T, Sheikh, A, Sinha, A, Subedi, D, Topping, W, Tweed, K, Underwood, S, Weir-Mccall, J, Zuhairy, H, Abbasi, T, Abohashem, S, Abramson, S, Al-Mallah, M, Kumar, M, Balmer-Swain, M, Berman, D, Bernheim, A, Bhatti, S, Biederman, R, Bieging, E, Bingham, S, Bloom, S, Blue, S, Borges, A, Branch, K, Bravo, P, Buddhe, S, Budoff, M, Bullock-Palmer, R, Cahill, M, Candela, C, Cao, J, Chatterjee, S, Chatzizisis, Y, Chaudhuri, N, Cheezum, M, Chelliah, A, Chen, T, Chen, M, Chen, L, Chokshi, A, Chung, J, Danciu, S, Desisto, W, Dilorenzo, M, Doukky, R, Duvall, W, Ferencik, M, Foster, C, Fuisz, A, Gannon, M, German, D, Gerson, M, Geske, 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H., Lenturut-Katal D., Castillo M., Ortellado J., Akhter A., Cader F. A., Hussain R., Khan S. R., Mandal T., Nasreen F., An Y., Cao D., Gong L., Hou Y., Jia C., Li T., Li C., Liu H., Liu W., Liu J., Ng M. -Y., Shi H., Tang C., Wang X., Wang Z., Wang Y., Wu J., Yi Y., Yuan L., Zhang T., Zhang L., Chavez E., Cruz C., Llontop C., Morales R., Abrihan P., Bustos-Barroso A., Duldulao-Ogbac M., Eduarte C., Obaldo J., Quinon A., San Juan B., San Juan C. J., Sauler-Gomez M. R., Uy M., Kostkiewicz M., Kunikowska J., Teresinska A., Urbanik T., Bettencourt N., Fontes-Carvalho R., Gavina C., Goncalves L., Macedo F., Moreno N., Sousa C., Timoteo A. T., Vidigal M. J., Al Heidous M., Ramanathan S., Arnous S., Aytani S., Byrne A., Gleeson T., Kerins D., O'Brien J., Bang J. -I., Bom H., Cheon M., Cheon G. J., Cho S. -G., Hong C. M., Jeong Y. H., Kang W. J., Kang Y. -K., Kim J. -Y., Oh S. W., So Y., Song H. -C., Won K. S., Yoo S. W., Mitevska I., Vavlukis M., Salobir B. G., Stalc M., Benedek T., Pop M., Stan C., Ansheles A., Dariy O., Gagarina N., Itskovich I., Karalkin A., Kokov A., Marina G., Migunova E., Pospelov V., Ryzhkova D., Sayfullina G., Sergienko V., Shurupova I., Vakhromeeva M., Valiullina N., Zavadovsky K., Zhuravlev K., Abazid R., Al Garni T., Alasnag M., Aljizeeri A., Amer H., Amro A., Hamdy H., Smettei O., Saranovic D. S., Vlajkovic M., Keng F., See J., Berecova Z., Mistinova J. P., Evbuomwan O., Govender N., Hack J., Hadebe B., Hlongwa K., Kaplan M., Lakhi H., Milos K., Modiselle M., More S., Muambadzi N., Scholtz L., Barreiro-Perez M., Blanco I., Broncano J., Camarero A., Casans-Tormo I., De Haro J., Flotats A., Garcia E., Mendiguchia C. G., Jimenez-Heffernan A., Leta R., Diaz J. L., Vega L. L., Manovel-Sanchez A., Monzonis A. M., Patrut B., Pubul V., Perez R. R., Zeidan N., Nanayakkara D., Suliman A., Engblom H., Murtadha M., Ostenfeld E., Simonsson M., Alkadhi H., Buechel R. R., Burger P., Grani C., Kamani C., Kawel-Bohm N., Klaeser B., Manka R., Prior J., Kaewchur T., Khiewvan B., Kositwattanarerk A., Namwongprom S., Thientunyakit T., Sayman H. B., Yuksel M., Sebikali M. J., Okello E., Korol P., Noverko I., Satyr M., Ahmad T., Alfakih K., Andrade I., Buckingham S., Bularga A., Carpenter J. -P., Cole G., Cusack D., David S., Davis P., Fairbairn T., Ghosh A., Ramkumar P. G., Hamilton M., Haque F., Hudson B., Johnstone A., Karthikeyan V. J., Kay M., Khan M. A., Kitt J., Low C. S., Mcalindon E., Mccreavy D., Morrissey B., Motwani M., Na D., Nicol E., Patel D., Rodrigues J., Rofe C., Schofield R., Semple T., Sheikh A., Sinha A., Subedi D., Topping W., Tweed K., Underwood S. R., Weir-Mccall J., Zuhairy H., Abbasi T., Abohashem S., Abramson S., Al-Mallah M., Kumar M. A., Balmer-Swain M., Berman D., Bernheim A., Bhatti S., Biederman R., Bieging E., Bingham S., Bloom S., Blue S., Borges A., Branch K., Bravo P., Buddhe S., Budoff M., Bullock-Palmer R., Cahill M., Candela C., Cao J., Chatterjee S., Chatzizisis Y., Chaudhuri N. R., Cheezum M., Chelliah A., Chen T., Chen M., Chen L., Chokshi A., Chung J., Danciu S., DeSisto W., Dilorenzo M., Doukky R., Duvall W., Ferencik M., Foster C., Fuisz A., Gannon M., German D., Gerson M., Geske J., Hage F., Haider A., Haider S., Hamirani Y., Hassen K., Hendel R., Henkel J., Horgan S., Hyun M., Janardhanan R., Jerome S., Kalra D., Kassop D., Kinkhabwala M., Kinzfogl G., Koch B., Koweek L., Krepp J., Kwon Y., Layer J., Lesser J., Leung S., Lisske B., Magurany K., Markowitz J., Mccullough B., Moalemi A., Moffitt C., Montanez J., Moore W., Morayati S., Mossa-Basha M., Mrsic Z., Murthy V., Nagpal P., Nelson K., Nijjar P., O'Quinn R., Passen E., Patil P., Pursnani A., Quachang N., Rabbat M., Ranjan P., Lozano P. R., Schemmer M., Seifried R., Shah N., Shah A., Shanbhag S., Sharma G., Skotnicki R., Sobczak M., Soman P., Sorrell V., Srichai M., Streeter J., Strickland L., Suliman S., Tebyanian N., Thomas D., Thompson R., Uretsky S., Vallurupalli S., Vandyck-Acquah M., Verma V., Villines T., Weinstein J., Wolinsky D., Zareba K., Zgaljardic M., Beretta M., Ferrando R., Kapitan M., Mut F., Djuraev O., Rozikhodjaeva G., Vera L., Duc B. D., Nguyen X. C., and Hiep Nguyen P. M.

Abstract

Background: The extent to which health care systems have adapted to the COVID-19 pandemic to provide necessary cardiac diagnostic services is unknown. Objectives: The aim of this study was to determine the impact of the pandemic on cardiac testing practices, volumes and types of diagnostic services, and perceived psychological stress to health care providers worldwide. Methods: The International Atomic Energy Agency conducted a worldwide survey assessing alterations from baseline in cardiovascular diagnostic care at the pandemic's onset and 1 year later. Multivariable regression was used to determine factors associated with procedure volume recovery. Results: Surveys were submitted from 669 centers in 107 countries. Worldwide reduction in cardiac procedure volumes of 64% from March 2019 to April 2020 recovered by April 2021 in high- and upper middle-income countries (recovery rates of 108% and 99%) but remained depressed in lower middle- and low-income countries (46% and 30% recovery). Although stress testing was used 12% less frequently in 2021 than in 2019, coronary computed tomographic angiography was used 14% more, a trend also seen for other advanced cardiac imaging modalities (positron emission tomography and magnetic resonance; 22%-25% increases). Pandemic-related psychological stress was estimated to have affected nearly 40% of staff, impacting patient care at 78% of sites. In multivariable regression, only lower-income status and physicians’ psychological stress were significant in predicting recovery of cardiac testing. Conclusions: Cardiac diagnostic testing has yet to recover to prepandemic levels in lower-income countries. Worldwide, the decrease in standard stress testing is offset by greater use of advanced cardiac imaging modalities. Pandemic-related psychological stress among providers is widespread and associated with poor recovery of cardiac testing.

Published
2022

90. Enhancing the solar panels efficiency by reducing thermal radiation.

Author

Sivakumar, S., Ramanathan, S., Kumar, U. Mahesh, Deena, R., Hemanathan, C., and Babu, A. R.

Subjects
*SOLAR panels, *HEAT radiation & absorption, *ENERGY harvesting, *ENERGY consumption, *CLEAN energy, *SOLAR energy
Abstract

The conventional methods of power generation are not convenient for the modern world. Modern world needs modern technology to harvest energy to meet the energy demand. We are supposed to meet the energy demand by producing energy with zero pollutant's released to the surroundings. One of the most suitable ways of producing the energy without polluting the environment is harvesting the solar energy and converting it into electrical energy through Solar panels. The solar energy is the most natural and clean energy source. It is essential to enhance the efficiency of the solar panels in every feasible way to maximize their output. The excessive solar radiation heats the photovoltaic cells and affects the panel's ambient temperature. As a result, the panel's efficiency is affected. To rectify this problem a low thermal conductivity glass plate is installed over the panel to retard the thermal radiation. An air gap width of 12mm is provided between the photovoltaic cells and the low thermal conductivity glass plate. Due to the series of variation in the thermal conductivity of the default glass plate in the solar panel, air medium, and the glass plate we installed over the solar panel the thermal radiations are filtered and retarded in each layer. As a result, the temperature of the solar panel never rises too high, and the efficiency can be improved. It is experimentally conducted, and the results and conclusions are detailed in this paper. [ABSTRACT FROM AUTHOR]

Published
2023
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91. Sorafenib plus intensive chemotherapy in newly diagnosed FLT3-ITD AML:a randomized, placebo-controlled study by the ALLG.

Author

Loo, S, Roberts, AW, Anstee, NS, Kennedy, GA, He, SZ-X, Schwarer, AP, Enjeti, AK, D'Rozario, J, Marlton, P, Bilmon, I, Taper, JM, Cull, G, Tiley, C, Verner, E, Hahn, U, Hiwase, DK, Iland, HJ, Murphy, NE, Ramanathan, S, Reynolds, J, Ong, DM, Tiong, IS, Wall, M, Murray, M, Rawling, T, Leadbetter, J, Rowley, L, Latimer, M, Yuen, SLS, Ting, SB, Fong, CY, Morris, KL, Bajel, A, Seymour, JF, Levis, MJ, Wei, AH, Loo, S, Roberts, AW, Anstee, NS, Kennedy, GA, He, SZ-X, Schwarer, AP, Enjeti, AK, D'Rozario, J, Marlton, P, Bilmon, I, Taper, JM, Cull, G, Tiley, C, Verner, E, Hahn, U, Hiwase, DK, Iland, HJ, Murphy, NE, Ramanathan, S, Reynolds, J, Ong, DM, Tiong, IS, Wall, M, Murray, M, Rawling, T, Leadbetter, J, Rowley, L, Latimer, M, Yuen, SLS, Ting, SB, Fong, CY, Morris, KL, Bajel, A, Seymour, JF, Levis, MJ, and Wei, AH

Abstract

Sorafenib maintenance improves outcome after hematopoietic cell transplant (HCT) for patients with FLT3-ITD acute myeloid leukemia (AML). Although promising outcomes have been reported for sorafenib plus intensive chemotherapy, randomized data are limited. This placebo-controlled, phase 2 study (ACTRN12611001112954) randomized 102 patients 18-65 years (2:1) to sorafenib vs placebo (days 4-10) combined with intensive induction; idarubicin 12mg/m2 days 1-3 plus cytarabine 1.5g/m2 twice daily on days 1,3,5,7 (18-55 years) or 100mg/m2 days 1-7 (56-65 years), consolidation therapy, followed by maintenance treatment for 12 months (post-HCT excluded) in newly diagnosed FLT3-ITD AML. Four patients were excluded from modified intention-to-treat final analysis (3 not dosed and 1 later found to be FLT3-ITD negative). Rates of complete remission (CR)/CR with incomplete hematologic recovery (CR/CRi) were high in both arms (sorafenib 78%/9%, placebo 70%/24%). With 49.1 months median follow-up, the primary endpoint of event-free survival (EFS) was not improved by sorafenib (2-year EFS 47.9% vs 45.4%)(hazard ratio [HR] 0.87;95% confidence interval [CI] 0.51-1.51, p=0.61). Two-year overall survival (OS) was 67% in the sorafenib arm and 58% in the placebo arm (HR 0.76; 95% CI 0.42-1.39). For patients transplanted in first remission, 2-year OS was 84% and 67% in the sorafenib and placebo arms, respectively (HR 0.45;95% CI 0.18-1.12, p=0.08). In exploratory analyses, FLT3-ITD measurable residual disease negative status (<0.001%) post-induction was associated with improved 2-year OS (83% vs 60%) (HR 0.4;95% CI 0.17-0.93, p=0.028). In conclusion, routine use of pre-transplant sorafenib plus chemotherapy in unselected patients with FLT3-ITD AML is not supported by this study.

Published
2023

92. Genomic analyses in Cornelia de Lange Syndrome and related diagnoses: Novel candidate genes, genotype-phenotype correlations and common mechanisms.

Author

Kaur, M, Blair, J, Devkota, B, Fortunato, S, Clark, D, Lawrence, A, Kim, J, Do, W, Semeo, B, Katz, O, Mehta, D, Yamamoto, N, Schindler, E, Al Rawi, Z, Wallace, N, Wilde, JJ, McCallum, J, Liu, J, Xu, D, Jackson, M, Rentas, S, Tayoun, AA, Zhe, Z, Abdul-Rahman, O, Allen, B, Angula, MA, Anyane-Yeboa, K, Argente, J, Arn, PH, Armstrong, L, Basel-Salmon, L, Baynam, G, Bird, LM, Bruegger, D, Ch'ng, G-S, Chitayat, D, Clark, R, Cox, GF, Dave, U, DeBaere, E, Field, M, Graham, JM, Gripp, KW, Greenstein, R, Gupta, N, Heidenreich, R, Hoffman, J, Hopkin, RJ, Jones, KL, Jones, MC, Kariminejad, A, Kogan, J, Lace, B, Leroy, J, Lynch, SA, McDonald, M, Meagher, K, Mendelsohn, N, Micule, I, Moeschler, J, Nampoothiri, S, Ohashi, K, Powell, CM, Ramanathan, S, Raskin, S, Roeder, E, Rio, M, Rope, AF, Sangha, K, Scheuerle, AE, Schneider, A, Shalev, S, Siu, V, Smith, R, Stevens, C, Tkemaladze, T, Toimie, J, Toriello, H, Turner, A, Wheeler, PG, White, SM, Young, T, Loomes, KM, Pipan, M, Harrington, AT, Zackai, E, Rajagopalan, R, Conlin, L, Deardorff, MA, McEldrew, D, Pie, J, Ramos, F, Musio, A, Kline, AD, Izumi, K, Raible, SE, Krantz, ID, Kaur, M, Blair, J, Devkota, B, Fortunato, S, Clark, D, Lawrence, A, Kim, J, Do, W, Semeo, B, Katz, O, Mehta, D, Yamamoto, N, Schindler, E, Al Rawi, Z, Wallace, N, Wilde, JJ, McCallum, J, Liu, J, Xu, D, Jackson, M, Rentas, S, Tayoun, AA, Zhe, Z, Abdul-Rahman, O, Allen, B, Angula, MA, Anyane-Yeboa, K, Argente, J, Arn, PH, Armstrong, L, Basel-Salmon, L, Baynam, G, Bird, LM, Bruegger, D, Ch'ng, G-S, Chitayat, D, Clark, R, Cox, GF, Dave, U, DeBaere, E, Field, M, Graham, JM, Gripp, KW, Greenstein, R, Gupta, N, Heidenreich, R, Hoffman, J, Hopkin, RJ, Jones, KL, Jones, MC, Kariminejad, A, Kogan, J, Lace, B, Leroy, J, Lynch, SA, McDonald, M, Meagher, K, Mendelsohn, N, Micule, I, Moeschler, J, Nampoothiri, S, Ohashi, K, Powell, CM, Ramanathan, S, Raskin, S, Roeder, E, Rio, M, Rope, AF, Sangha, K, Scheuerle, AE, Schneider, A, Shalev, S, Siu, V, Smith, R, Stevens, C, Tkemaladze, T, Toimie, J, Toriello, H, Turner, A, Wheeler, PG, White, SM, Young, T, Loomes, KM, Pipan, M, Harrington, AT, Zackai, E, Rajagopalan, R, Conlin, L, Deardorff, MA, McEldrew, D, Pie, J, Ramos, F, Musio, A, Kline, AD, Izumi, K, Raible, SE, and Krantz, ID

Abstract

Cornelia de Lange Syndrome (CdLS) is a rare, dominantly inherited multisystem developmental disorder characterized by highly variable manifestations of growth and developmental delays, upper limb involvement, hypertrichosis, cardiac, gastrointestinal, craniofacial, and other systemic features. Pathogenic variants in genes encoding cohesin complex structural subunits and regulatory proteins (NIPBL, SMC1A, SMC3, HDAC8, and RAD21) are the major pathogenic contributors to CdLS. Heterozygous or hemizygous variants in the genes encoding these five proteins have been found to be contributory to CdLS, with variants in NIPBL accounting for the majority (>60%) of cases, and the only gene identified to date that results in the severe or classic form of CdLS when mutated. Pathogenic variants in cohesin genes other than NIPBL tend to result in a less severe phenotype. Causative variants in additional genes, such as ANKRD11, EP300, AFF4, TAF1, and BRD4, can cause a CdLS-like phenotype. The common role that these genes, and others, play as critical regulators of developmental transcriptional control has led to the conditions they cause being referred to as disorders of transcriptional regulation (or "DTRs"). Here, we report the results of a comprehensive molecular analysis in a cohort of 716 probands with typical and atypical CdLS in order to delineate the genetic contribution of causative variants in cohesin complex genes as well as novel candidate genes, genotype-phenotype correlations, and the utility of genome sequencing in understanding the mutational landscape in this population.

Published
2023

93. A Network of Sites and Upskilled Therapists to Deliver Best-Practice Stroke Rehabilitation of the Arm: Protocol for a Knowledge Translation Study

Author

Carey, LM, Cahill, LS, Blennerhassett, JM, Nilsson, M, Lannin, NA, Thijs, V, Hillier, S, Cadilhac, DA, Donnan, GA, Morris, ME, Churilov, L, Walker, M, Ramanathan, S, Pollack, M, May, E, Cloud, GC, McGowan, S, Wijeratne, T, Budge, M, McKinnon, F, Olver, J, Hogg, T, Murray, M, Haslam, B, Koukoulas, I, Nielsen, B, Mak-Yuen, Y, Turville, M, Neilson, C, Butler, A, Kim, J, Matyas, TA, Carey, LM, Cahill, LS, Blennerhassett, JM, Nilsson, M, Lannin, NA, Thijs, V, Hillier, S, Cadilhac, DA, Donnan, GA, Morris, ME, Churilov, L, Walker, M, Ramanathan, S, Pollack, M, May, E, Cloud, GC, McGowan, S, Wijeratne, T, Budge, M, McKinnon, F, Olver, J, Hogg, T, Murray, M, Haslam, B, Koukoulas, I, Nielsen, B, Mak-Yuen, Y, Turville, M, Neilson, C, Butler, A, Kim, J, and Matyas, TA

Abstract

Implementation of evidence-informed rehabilitation of the upper limb is variable, and outcomes for stroke survivors are often suboptimal. We established a national partnership of clinicians, survivors of stroke, researchers, healthcare organizations, and policy makers to facilitate change. The objectives of this study are to increase access to best-evidence rehabilitation of the upper limb and improve outcomes for stroke survivors. This prospective pragmatic, knowledge translation study involves four new specialist therapy centers to deliver best-evidence upper-limb sensory rehabilitation (known as SENSe therapy) for survivors of stroke in the community. A knowledge-transfer intervention will be used to upskill therapists and guide implementation. Specialist centers will deliver SENSe therapy, an effective and recommended therapy, to stroke survivors in the community. Outcomes include number of successful deliveries of SENSe therapy by credentialled therapists; improved somatosensory function for stroke survivors; improved performance in self-selected activities, arm use, and quality of life; treatment fidelity and confidence to deliver therapy; and for future implementation, expert therapist effect and cost-effectiveness. In summary, we will determine the effect of a national partnership to increase access to evidence-based upper-limb sensory rehabilitation following stroke. If effective, this knowledge-transfer intervention could be used to optimize the delivery of other complex, evidence-based rehabilitation interventions.

Published
2023

94. Impact assessment of the Centre for Research Excellence in Stroke Rehabilitation and Brain Recovery.

Author

Ramanathan, S, Lynch, E, Bernhardt, J, Nilsson, M, Cadilhac, DA, Carey, L, Middleton, S, Chamberlain, J, Walker, FR, Reeves, P, Searles, A, Ramanathan, S, Lynch, E, Bernhardt, J, Nilsson, M, Cadilhac, DA, Carey, L, Middleton, S, Chamberlain, J, Walker, FR, Reeves, P, and Searles, A

Abstract

BACKGROUND: Research impact is an emerging measure of research achievement alongside traditional academic outputs such as publications. We present the results of applying the Framework to Assess the Impact from Translational health research (FAIT) to the Centre for Research Excellence (CRE) in Stroke Rehabilitation and Brain Recovery (CRE-Stroke, 2014-2019) and report on the feasibility and lessons from the application of FAIT to a CRE rather than a discrete research project. METHODS: Data were gathered via online surveys, in-depth interviews, document analysis and review of relevant websites/databases to report on the three major FAIT methods: the modified Payback Framework, an assessment of costs against monetized consequences, and a narrative account of the impact generated from CRE-Stroke activities. FAIT was applied during the last 4 years of CRE-Stroke operation. RESULTS: With an economic investment of AU$ 3.9 million over 5 years, CRE-Stroke delivered a return on investment that included AU$ 18.8 million in leveraged grants, fellowships and consultancies. Collectively, CRE-Stroke members produced 354 publications that were accessed 470,000 times and cited over 7220 times. CRE-Stroke supported 26 PhDs, 39 postdocs and seven novice clinician researchers. There were 59 capacity-building events benefiting 744 individuals including policy-makers and consumers. CRE-Stroke created research infrastructure (including a research register of stroke survivors and a brain biobank), and its global leadership produced international consensus recommendations to influence the stroke research landscape worldwide. Members contributed to the Australian Living Stroke Guidelines: four researchers' outputs were directly referenced. Based only on the consequences that could be monetized, CRE-Stroke returned AU$ 4.82 for every dollar invested in the CRE. CONCLUSION: This case example in the developing field of impact assessment illustrates how researchers can use evidence to demonstr

Published
2023

95. Light interception and radiation use efficiency (RUE) in maize (Zea mays. L) intercropping with greengram (Vigna radiata L.)

Author

T, Govindaraj, Maragatham, N., Ramanathan , S P., Geethalakshmi, V., Kalarani, M. K., T, Govindaraj, Maragatham, N., Ramanathan , S P., Geethalakshmi, V., and Kalarani, M. K.

Abstract

Intercropping is growing two or more crop species simultaneously, different canopy architectures by row configuration, changing light interception, radiation utilisation, and increased yield. The present study aimed to evaluate different intercropping systems affected light interception per cent and radiation use efficiency in maize (Zea mays L.) intercropping with greengram (Vigna radiata L.) different ratios. Field experiments were conducted for Kharif 2022 and Rabi 2022-2023 seasons, which were laid out in a split-plot design and replicated three times. Three Nitrogen levels viz., N1 - 75 % RDN (Recommended dose of Nitrogen), N2 – 100% RDN, N3-125% RDN had taken as the main plot and three intercropping treatments were taken as subplot viz., M2G2- replacement series (two row of maize and two row of Greengram), M4G2- replacement series (four rows of maize and two row of Greengram), M2G3-paired row system (two rows of maize and three rows of Greengram), and sole maize. Both light interception and radiation use efficiency were significantly affected by intercropping systems. Light interception per cent of the main crop (maize) was significantly higher (69.0, 75.5 and 71.0 % during Kharif and 60.1, 78.1 and 76.6 during rabi) at vegetative, flowering and maturity phases, respectively. The Kharif 2022 and Rabi 2022-2023 maximum Radiation Use Efficiency (RUE) of Maize intercropping with green gram (maize + greengram) was higher in T12 (M2G3 paired row with 125 % Recommended Dose of Nitrogen) recorded as 2.46 (Kharif) and 1.43 (rabi). The outcome might be utilised to optimise the row configuration of intercropping design, explain the mechanism of intercropping on light utilisation, and improve radiation use efficiency.

Published
2023

96. Culturally Informed Australian Aboriginal and Torres Strait Islander Evaluations: A Scoping Review.

Author

Vine, K, Benveniste, T, Ramanathan, S, Longman, J, Williams, M, Laycock, A, Matthews, V, Vine, K, Benveniste, T, Ramanathan, S, Longman, J, Williams, M, Laycock, A, and Matthews, V

Abstract

Rigorous and effective evaluations inform policy and service delivery and create evidence of program impacts and outcomes for the communities they are designed to support. Genuine engagement of communities is a key feature of effective evaluation, building trust and enhancing relevancy for communities and providing meaningful outcomes and culturally relevant findings. This applies to Indigenous peoples' leadership and perspectives when undertaking evaluations on programs that involve Indigenous communities. This systematic scoping review sought to explore the characteristics of culturally informed evaluations and the extent of their application in Australia, including the use of specific evaluation tools and types of community engagement. Academic and grey literature were searched between 2003 and 2023, with 57 studies meeting the inclusion criteria. Over time, there was an increase in the number of culturally informed evaluations undertaken, predominantly in the health and wellbeing sector. Around a quarter used a tool specifically developed for Indigenous evaluations. Half of the publications included Indigenous authorship; however, most studies lacked detail on how evaluations engaged with communities. This review highlights the need for further development of evaluation tools and standardised reporting to allow for shared learnings and improvement in culturally safe evaluation practices for Aboriginal and Torres Strait Islander communities.

Published
2023

98. Effect of High Minimum Temperature and Enriched Night CO2 on Yield and Seed Quality of Black Gram (Vigna mungo) under Soil Plant Atmospheric Research (SPAR).

Author

Guna, M., Ramanathan, S. P., Geethalakshmi, V., Chandrakumar, K., Kokilavani, S., and Djanaguiraman, M.

Subjects
*BLACK gram, *SEED quality, *SEED yield, *PLANT-soil relationships, *HIGH temperatures, *SEED proteins, *CROP rotation, *SEED treatment
Abstract

Background: Black gram is a leguminous plant species. This pulse crop has been grown on the Indian subcontinent for a long time. Black gram a drought-resistant crop that grown both in the summer and the winter, usually in rotation with rice but occasionally in mixed farming. The objective of this research was to (i) quantify the short-term effects of high minimum temperature and enriched night CO2 (HMT and enCO2) on yield contribution factors and (ii) quantify seed quality parameters employing biochemical analysis. Methods: An investigation was carried out during summer 2021 and 2022 to evaluate the effect of high minimum temperature (ambient+3°C) and enriched night CO2 (600 ppm) (HMT and enCO2) on yield and seed quality parameters of black gram (Vigna mungo) under soil plant atmospheric research (SPAR) and ambient condition at Agro Climate Research Centre, Tamil Nadu Agricultural University, Coimbatore, Tamil Nadu with ten treatments which were replicated thrice. Result: Black gram yield and quality parameters were significantly (p=0.05) reduced under HMT and enCO2. Pooled data from two successive summer seasons revealed that stress from (i) 50 to 56 DAS (Days after sowing), the number of flowers dropped per plant significantly increased by 24% and pod setting percent decreased by 19.9% (ii) 43 to 49 DAS, grain yield and biomass/plant decreased by 25.4% and 16.2%, respectively. Seed quality parameters revealed that stress during 50 to 56 DAS, seed protein, total sugar content, polyphenols, calcium and iron decreased by 19.4%, 23.7%, 16.2%, 29.6% and 30.2%, respectively. The proline and phytic acid were statistically reduced by 53.9% and 59.1%, respectively stress during 50 to 56 DAS. Stress from 64 to 70 DAS, seed moisture content was significantly decreased by 32.1%. Overall, black gram yield and seed quality was negatively affected on two treatments: stress imposed from 43 to 49 DAS (T7) and stress imposed from 50 to 56 DAS (T8) (50% flowering to pod filling stage). [ABSTRACT FROM AUTHOR]

Published
2024
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