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301 results on '"Rollnik, Jens D."'

56. An unusual manifestation of Wilson disease presenting with burning feet syndrome

Author

Rollnik, Jens D., Rost, Imma, Marschall, Christoph, and Wetzel, Petra

Subjects
Foot diseases -- Risk factors, Foot diseases -- Genetic aspects, Foot diseases -- Case studies, Gene mutations -- Health aspects, Polyneuropathies -- Risk factors, Polyneuropathies -- Diagnosis, Polyneuropathies -- Case studies, Wilson's disease -- Diagnosis, Wilson's disease -- Complications and side effects, Wilson's disease -- Case studies, Health
Abstract

Background: Wilson disease is rarely associated with peripheral neuropathy. Case Report: We report on a 50 y old male with an unusual manifestation of Wilson disease. The patient presented with burning feet syndrome. Nerve conduction studies revealed a mild axonal and myelin damage. In genetic testing, a homozygous point mutation (c.3207C>A) on the ATP7B gene was found. Conclusions: Physicians should be aware that patients suffering from Wilson disease may present with a broad spectre of symptoms, including signs of polyneuropathy. Keywords: Wilson disease | burning feet syndrome | polyneuropathy, Introduction Wilson disease is known to cause a variety of neurological and multisystemic manifestations. It may affect liver function, cognition, behaviour, motor and osseomuscular system [1]. Among symptoms of central [...]

Published
2010

58. Criterion validity and sensitivity to change of the Early Rehabilitation Index (ERI): results from a German multi-center study

Author

Rollnik, Jens D., primary, Bertram, M., additional, Bucka, C., additional, Hartwich, M., additional, Jöbges, M., additional, Ketter, G., additional, Leineweber, B., additional, Mertl-Rötzer, M., additional, Nowak, D. A., additional, Platz, T., additional, Scheidtmann, K., additional, Thomas, R., additional, von Rosen, F., additional, Wallesch, C. W., additional, Woldag, H., additional, Peschel, P., additional, Mehrholz, J., additional, and Pohl, M., additional

Published
2016
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62. Comparison of fall prediction by the Hessisch Oldendorf Fall Risk Scale and the Fall Risk Scale by Huhn in neurological rehabilitation: an observational study.

Author

Hermann, Olena, Schmidt, Simone B., Boltzmann, Melanie, and Rollnik, Jens D.

Subjects
RISK factors of falling down, SCIENTIFIC observation, SENSITIVITY & specificity (Statistics), ACTIVITIES of daily living, REHABILITATION, NEUROSURGERY, CONFIDENCE intervals, ACCIDENTAL falls, RANGE of motion of joints, LONGITUDINAL method, NEUROLOGICAL disorders, REHABILITATION centers, RISK assessment, PREDICTIVE tests, RESEARCH methodology evaluation, ODDS ratio, MANN Whitney U Test, BARTHEL Index
Abstract

Objective: To calculate scale performance of the newly developed Hessisch Oldendorf Fall Risk Scale (HOSS) for classifying fallers and non-fallers in comparison with the Risk of Falling Scale by Huhn (FSH), a frequently used assessment tool. Design: A prospective observational trail was conducted. Setting: The study was performed in a large specialized neurological rehabilitation facility. Subjects: The study population (n = 690) included neurological and neurosurgery patients during neurological rehabilitation with varying levels of disability. Around the half of the study patients were independent and dependent in the activities of daily living (ADL), respectively. Interventions: Fall risk of each patient was assessed by HOSS and FSH within the first seven days after admission. Main measures: Event of fall during rehabilitation was compared with HOSS and FSH scores as well as the according fall risk. Scale performance including sensitivity and specificity was calculated for both scales. Results: A total of 107 (15.5%) patients experienced at least one fall. In general, fallers were characterized by an older age, a prolonged length of stay, and a lower Barthel Index (higher dependence in the ADL) on admission than non-fallers. The verification of fall prediction for both scales showed a sensitivity of 83% and a specificity of 64% for the HOSS scale, and a sensitivity of 98% with a specificity of 12% for the FSH scale, respectively. Conclusion: The HOSS shows an adequate sensitivity, a higher specificity and therefore a better scale performance than the FSH. Thus, the HOSS might be superior to existing assessments. [ABSTRACT FROM AUTHOR]

Published
2018
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67. Vibration-Induced Kinesthetic Illusions and Corticospinal Excitability Changes.

Author

Mancheva, Kapka, Rollnik, Jens D., Wolf, Werner, Dengler, Reinhard, and Kossev, Andon

Subjects
*ILLUSION (Philosophy), *TRANSCRANIAL magnetic stimulation, *MOTOR ability, *VIBRATION (Mechanics), *FLEXOR muscles
Abstract

The authors' aim was to investigate the changes of corticospinal excitability during kinesthetic illusions induced by tendon vibration. Motor-evoked potentials in response to transcranial magnetic stimulation were recorded from the vibrated flexor carpi radialis and its antagonist, extensor carpi radialis. The illusions were evoked under vision conditions without feedback for the position of the wrist (open or closed eyes). In these two conditions motor-evoked potential changes during vibration in the antagonist were not identical. This discrepancy may be a result of 2 simultaneously acting, different and opposite influences and the balance between them depends on visual conditions. Thus, the illusion was accompanied by the facilitation of corticospinal excitability in both vibrated muscle and its antagonist. [ABSTRACT FROM PUBLISHER]

Published
2017
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100. Effects of acute alcohol withdrawal on memory performance in alcohol-dependent patients: a pilot study.

Author

Seifert, J&uouml;rgen, Seeland, Irina, Borsutzky, Mathias, Passie, Torsten, Rollnik, Jens D., Weise, Birgitt, Emrich, Hinderk M., and Schneider, Udo

Subjects
DETOXIFICATION (Substance abuse treatment), PATIENTS, MEMORY, DRUG withdrawal symptoms
Abstract

Studies on the neuropsychological performance in detoxified alcoholic patients often begin by acknowledging that there is a cognitive impairment to be found. Only little attention has been paid to date to the question as to how acute alcohol withdrawal might affect cognitive functions. Twenty-nine alcohol-dependent inpatients, nine in moderate alcohol withdrawal, treated with carbamazepine (group 1), 10 in mild alcohol withdrawal without pharmacological treatment (group 2), 10 in mild alcohol withdrawal with carbamazepine treatment (group 3) and 31 healthy subjects as controls (group 4) underwent repeated investigations using memory tests. The tests were performed on the first, third, seventh and fourteenth days of withdrawal. Immediate free recall of a word-list was impaired in the three patient groups in comparison with the control group on the 1st day. Thereafter no significant differences could be revealed between patients and controls. In a word-list recognition test the memory functions were not impaired in group 1 and group 2 in comparison with the control subjects. However, patients in group 3 showed impairment in this recognition test in comparison with the healthy subjects on the first and third days. The present study suggests that acute alcohol withdrawal impairs memory functions, especially free recall. This should be considered in treatment interventions in the early days of withdrawal. [ABSTRACT FROM AUTHOR]

Published
2003
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